proteins talk
TRANSCRIPT
protein molecules
the things that make us live
(what our genes are for)
you’ve heard:a gene is a stored message
about how to build a specific protein.
you’ve heard:a gene is a stored message
about how to build a specific protein.
name some proteins you’ve heard of…
a protein molecule is a simple machine w
with a complex structure
Q. How do you make a simple machinethat does a very specific job?
Q. How do you make a simple machinethat does a very specific job?
A. make it out of many (100-1000) tiny parts(of several different kinds)
Folding an amino acid chain correctly is a challenge
Predicting protein folding is also a challenge
how do we know about proteins’ shapes?
I can’t explain it
protein shape is dynamic
grabflip
tweak
‘allostery’ = flipping between 2 or 3 alternate conformations
allosteric flipping has causes……and effects.
This means a protein can act as a switch -responding (in specific way) to a specific stimulus.