publication list 2015, part 1 - helmholtz zentrum münchen filepublication list 2015, part 1...

Publication List 2015, Part 1

2015-05-18

# joint first authors° corresponding authors

HMGU authors are given in bold lettersComprehensive Pneumology Center

page 1 of 108

Bousquet, J.°, Antò, J.M., Berkouk, K., Gergen, P.J., Pinto Antunes, J., Augé, P., Camuzat, T., Bringer, J., Mercier, J., Best, N., Bourret, R., Akdis, M., Arshad, S.H., Bedbrook, A., Berr, C., Bush, A., Cavalli, G., Charles, M.A., Clavel-Chapelon, F., Gillman, M., Gold, D.R., Goldberg, M., Holloway, J.W., Iozzo, P., Jacquemin, S., Jeandel, C., Kauffmann, F., Keil, T., Koppelman, G.H., Krauss-Etschmann, S. , Kuh, D., Lehmann, S., Lodrup Carlsen, K.C., Maier, D., Méchali, M., Melén, E., Moatti, J.P., Momas, I., Nérin, P., Postma, D.S., Ritchie, K., Robine, J.M., Samolinski, B., Siroux, V., Slagboom, P.E., Smit, H.A., Sunyer, J., Valenta, R., van de Perre, P., Verdier, J.M., Vrijheid, M., Wickman, M., Yiallouros, P.K., Zins, M.: Developmental determinants in non-communicable chronic diseases and ageing. Thorax, DOI: 10.1136/thoraxjnl-2014-206304 (2015)

Chillappagari, S., Venkatesan, S., Garapati, V., Mahavadi, P., Munder, A., Seubert, A., Sarode, G., Guenther, A., Schmeck, B.T., Tuemmler, B., Henke, M.O.°: Impaired TLR4 and HIF expression in cystic fibrosis bronchial epithelial cells downregulates hemeoxygenase-1 and alters iron homeostasis in vitro. Am. J. Physiol. Lung Cell Mol. Physiol. 307, L791-L799 (2014)

Dau, T., Sarker, R.S. , Yildirim, A.Ö. , Eickelberg, O. , Jenne, D. °: Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors. Nat. Commun. 6:6722 (2015)

Fernandez, I.E. , Heinzelmann, K. , Verleden, S., Eickelberg, O. °: Characteristic patterns in the fibrotic lung. Comparing idiopathic pulmonary fibrosis with chronic lung allograft dysfunction. Ann. Am. Thorac. Soc. 12, S34-S41 (2015)

Hellbach, K., Yaroshenko, A., Meinel, F.G., Yildirim, A.Ö. , Conlon, T.M. , Bech, M., Mueller, M., Velroyen, A., Notohamiprodjo, M., Bamberg, F., Auweter, S., Reiser, M., Eickelberg, O. , Pfeiffer, F.°: In vivo dark-field radiography for early diagnosis and staging of pulmonary emphysema. Invest. Radiol., DOI: 10.1097/RLI.0000000000000147 (2015)

Hinkofer, L.C. , Hummel, A.M., Stone, J.H., Hoffman, G.S., Merkel, P.A., Spiera, E.R., St. Clair, W., McCune, J.W., Davis, J.C., Specks, U., Jenne, D. °: Allosteric modulation of proteinase 3 activity by anti-neutrophil cytoplasmic antibodies in granulomatosis with polyangiitis. J. Autoimmun. 59, 43-52 (2015)

Loss, G.°, Depner, M., Ulfman, L.H., van Neerven, R.J., Hose, A.J., Genuneit, J., Karvonen, A.M., Hyvärinen, A., Kaulek, V., Roduit, C., Weber, J., Lauener, R., Pfefferle, P.I., Pekkanen, J., Vaarala, O., Dalphin, J.C., Riedler, J., Braun-Fahrländer, C., von Mutius, E.R.M. , Ege, M.J. : Consumption of unprocessed cow's milk protects infants from common respiratory infections. J. Allergy Clin. Immunol. 135, 56-62 (2015)

MacKenzie, B., Henneke, I., Hezel, S., Al Alam, D., El Agha, E., Chao, C.M., Quantius, J., Wilhelm, J., Jones, M., Goth, K., Li, X., Seeger, W., Königshoff, M. , Herold, S., Rizvanov, A.A., Günther, A., Bellusci, S.°: Attenuating endogenous Fgfr2b ligands during bleomycin-induced lung fibrosis does not compromise murine lung repair. Am. J. Physiol. Lung Cell Mol. Physiol., DOI: 10.1152/ajplung.00291.2014 (2015)


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HMGU authors are given in bold lettersComprehensive Pneumology Center

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Marcos, V., Zhou-Suckow, Z., Yildirim, A.Ö. , Bohla, A. , Hector, A., Vitkov, L., Krautgartner, W.D., Stoiber, W., Griese, M., Eickelberg, O. , Mall, M.A., Hartl, D.°: Free DNA in cystic fibrosis airway fluids correlates with airflow obstruction. Mediators Inflamm. 2015:408935 (2015)

Meiners, S. °, Eickelberg, O. , Königshoff, M. : Hallmarks of the ageing lung. Eur. Respir. J. 45, 807-827 (2015)

Sarker, R.S. , John-Schuster, G. , Bohla, A. , Mutze, K. , Burgstaller, G. , Bedford, M.T., Königshoff, M. , Eickelberg, O. , Yildirim, A.Ö. °: CARM1 regulates alveolar epithelial senescence and elastase-induced emphysema susceptibility. Am. J. Respir. Cell Mol. Biol., DOI: 10.1165/rcmb.2014-0216OC (2015)

Schamberger, A.C. , Staab-Weijnitz, C.A. , Mise-Racek, N. , Eickelberg, O. °: Cigarette smoke alters primary human bronchial epithelial cell differentiation at the air-liquid interface. Sci. Rep. 5:8163 (2015)

Schloter, M. °, Kostric, M. , Schöler, A. , Treichel, N. , Krauss-Etschmann, S. , Berg, G.: Die Bedeutung des humanen Mikrobioms für die menschliche Gesundheit. BIOspektrum 21, 39-40 (2015)

Thannickal, V.J., Murthy, M., Balch, W.E., Chandel, N.S., Meiners, S. , Eickelberg, O. , Selman, M., Pardo, A., White, E.S., Levy, B.D., Busse, P.J., Tuder, R.M., Antony, V.B., Sznajder, J.I., Budinger, G.R.°: Blue journal conference : Aging and susceptibility to lung disease. Am. J. Respir. Crit. Care Med. 191, 261-269 (2015)

Uhl, F. , Vierkotten, S. , Wagner, D. , Burgstaller, G. , Costa, R. , Koch, I., Lindner, M., Meiners, S. , Eickelberg, O. , Königshoff, M. °: Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures. Eur. Respir. J., DOI: 10.1183/09031936.00183214 (2015)

van Rijt, S.H. °, Bölükbas, D.A., Argyo, C., Datz, S., Lindner, M. , Eickelberg, O. , Königshoff, M. , Bein, T., Meiners, S. : Protease-mediated release of chemotherapeutics from mesoporous silica nanoparticles to ex vivo human and mouse lung tumors. ACS Nano 9, 2377-2389 (2015)


2015-05-20


HMGU authors are given in bold lettersCooperation Group Comprehensive Molecular Analytics

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Breuer, D.#°, Dragan, G.C. #, Friedrich, C., Möhlmann, C., Zimmermann, R. : Development and field testing of a miniaturized sampling system for simultaneous sampling of vapours and droplets. Environ. Sci. Process Impacts 17, 278-287 (2015)

Bruns, E.A., Krapf, M., Orasche, J. , Huang, Y. , Zimmermann, R. , Drinovec, L., Močnik, G., El Haddad, I., Slowik, J.G., Dommen, J., Baltensperger, U.R.S., Prevot, A.S.H.°: Characterization of primary and secondary wood combustion products generated under different burner loads. Atmos. Chem. Phys. 15, 2825-2841 (2015)

He, X., Hartlieb, E., Rothmund, L., Waschke, J., Wu, X., van Landuyt, K.L., Milz, S., Michalke, B. , Hickel, R., Reichl, F.X., Högg, C.H.°: Intracellular uptake and toxicity of three different Titanium particles. Dent. Mater. 31, 734-744 (2015) [published online 2014]

Hertz-Schünemann, R. , Ehlert, S. , Streibel, T. , Liu, C., McAdam, K., Baker, R.R., Zimmermann, R. °: High-resolution time and spatial imaging of tobacco and its pyrolysis products during a cigarette puff by microprobe sampling photoionisation mass spectrometry. Anal. Bioanal. Chem. 407, 2293-2299 (2015)

Kanashova, T.#, Popp, O.#, Orasche, J. , Karg, E.W., Harndorf, H., Stengel, B., Sklorz, M., Streibel, T., Zimmermann, R. , Dittmar, G.A.G.°: Differential proteomic analysis of mouse macrophages exposed to adsorbate-loaded heavy fuel oil derived combustion particles using an automated sample-preparation workflow. Anal. Bioanal. Chem., DOI: 10.1007/s00216-015-8595-4 (2015)

Kleeblatt, J. , Stengel, B., Radischat, C. , Passig, J. , Streibel, T. , Sippula, O., Rabe, R., Harndorf, H., Zimmermann, R. °: Needle trap sampling thermal-desorption resonance enhanced multiphoton ionization time-of-flight mass spectrometry for analysis of marine diesel engine exhaust. Anal. Methods 7, 3608-3617 (2015)

Kleeblatt, J. , Schubert, J.K., Zimmermann, R. °: Rapid detection of gaseous compounds by needle trap sampling and direct thermal-desorption photoionization mass spectrometry: Concept and demonstrative application to breath gas analysis. Anal. Chem. 87, 1773–1781 (2015)

Leuchner, M.°, Gubo, S., Schunk, C., Wastl, C., Kirchner, M. , Menzel, A., Plaß-Dülmer, C.: Can positive matrix factorization help to understand patterns of organic trace gases at the continental Global Atmosphere Watch site Hohenpeissenberg? Atmos. Chem. Phys. 15, 1221-1236 (2015)

Müller, L. , Jakobi, G. , Orasche, J. , Karg, E.W. , Sklorz, M., Abbaszade, G. , Weggler, B.A. , Jing, L., Schnelle-Kreis, J. °, Zimmermann, R. : Online determination of polycyclic aromatic hydrocarbon formation from a flame soot generator. Anal. Bioanal. Chem., DOI: 10.1007/s00216-015-8549-x (2015)

Nozière, B.°, Kalberer, M.°, Claeys, M.°, Allan, J., D'Anna, B., Decesari, S., Finessi, E., Glasius, M., Grgić, I., Hamilton, J.F., Hoffmann, T., Iinuma, Y., Jaoui, M., Kahnt, A., Kampf, C.J., Kourtchev, I., Maenhaut, W., Marsden, N., Saarikoski, S., Schnelle-Kreis, J. , Surratt, J.D., Szidat, S., Szmigielski, R., Wisthaler, A.: The molecular identification of organic compounds in the atmosphere: State of the art and challenges. Chem. Rev., DOI: 10.1021/cr5003485 (2015)


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HMGU authors are given in bold lettersCooperation Group Comprehensive Molecular Analytics

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Otto, S., Streibel, T. °, Erdmann, S., Sklorz, M. , Schulz-Bull, D., Zimmermann, R. : Application of pyrolysis-mass spectrometry and pyrolysis-gas chromatography-mass spectrometry with electron-ionization or resonance-enhanced-multi-photon ionization for characterization of crude oils. Anal. Chim. Acta 855, 60-69 (2015)

Radischat, C., Sippula, O., Stengel, B., Klingbeil, S., Sklorz, M. , Rabe, R., Streibel, T. °, Harndorf, H., Zimmermann, R. : Real-time analysis of organic compounds in ship engine aerosol emissions using resonance-enhanced multiphoton ionisation and proton transfer mass spectrometry. Anal. Bioanal. Chem., DOI: 10.1007/s00216-015-8465-0 (2015)

Reda, A. , Schnelle-Kreis, J. °, Orasche, J. , Abbaszade, G. , Lintelmann, J. , Arteaga-Salas, J.M. , Stengel, B., Rabe, R., Harndorf, H., Sippula, O., Streibel, T. , Zimmermann, R. : Gas phase carbonyl compounds in ship emissions: Differences between diesel fuel and heavy fuel oil operation. Atmos. Environ., DOI: 10.1016/j.atmosenv.2015.03.057 (2015)

Rüger, C.P., Sklorz, M. °, Schwemer, T., Zimmermann, R. : Characterisation of ship diesel primary particulate matter at the molecular level by means of ultra-high-resolution mass spectrometry coupled to laser desorption ionisation - comparison of feed fuel, filter extracts and direct particle measurements. Anal. Bioanal. Chem., DOI: 10.1007/s00216-014-8408-1 (2015)

Yang, J.Z., Röwer, C., Koy, C., Ruß, M., Rüger, C.P. , Zimmermann, R. , Fritschen, U.V., Bredell, M., Finke, J.C., Glocker, M.O.°: Mass spectrometric characterization of limited proteolysis activity in human plasma samples under mild acidic conditions. Methods, DOI: 10.1016/j.ymeth.2015.02.013 (2015)

Yttri, K.E.°, Schnelle-Kreis, J. , Maenhaut, W., Abbaszade, G. , Alves, C.A., Bjerke, A., Bonnier, N., Bossi, R., Claeys, M., Dye, C., Evtyugina, M.G., García Gacio, D., Hillamo, R.E.J., Hoffer, A.G., Hyder, M., Iinuma, Y., Jaffrezo, J.L., Kasper-Giebl, A., Kiss, G., López-Mahía, P.L., Pio, C., Piot, C., Ramirez-Santa-Cruz, C., Sciare, J., Teinilä, K., Vermeylen, R., Vicente, A.M., Zimmermann, R. : An intercomparison study of analytical methods used for quantification of levoglucosan in ambient aerosol filter samples. Atmos. Meas. Tech. 8, 125-147 (2015)

Zhang, Y.°, Huang, R.J., El Haddad, I., Ho, K.F., Cao, J., Han, Y., Zotter, P., Bozzetti, C., Daellenbach, K.R., Canonaco, F., Slowik, J.G., Salazar, G.A., Schwikowski, M., Schnelle-Kreis, J. , Abbaszade, G. , Zimmermann, R. , Baltensperger, U.R.S., Prevot, A.S.H., Szidat, S.°: Fossil vs. non-fossil sources of fine carbonaceous aerosols in four Chinese cities during the extreme winter haze episode of 2013. Atmos. Chem. Phys. 15, 1299-1312 (2015)

Zimmermann, R. °, Hertz-Schünemann, R., Ehlert, S., Liu, C., McAdam, K., Baker, R., Streibel, T. : Highly time-resolved imaging of combustion and pyrolysis product concentrations in solid fuel combustion: NO formation in a burning cigarette. Anal. Chem. 87, 1711-1717 (2015)


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HMGU authors are given in bold lettersGerman Center for Diabetes Reseach

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Auer, M., Tao, X., Roepke, Y., Stalla, G.K., Stieg, M., van Caenegem, E., Prehn, C. , Wang-Sattler, R. , Adamski, J. , T'sjoen, G.: Pilot study on the effects of cross-sex hormone treatment in transsexual persons on metabolism by means of metabolomics profiling. Poster: Exp. Clin. Endocrinol. Diabet. 123 (2015)

Berti, L. , Irmler, M. , Zdichavsky, M., Meile, T., Böhm, A. , Stefan, N. , Fritsche, A. , Beckers, J. , Königsrainer, A., Häring, H.-U. , Hrabě de Angelis, M. , Staiger, H. °: Fibroblast growth factor 21 is elevated in metabolically unhealthy obesity and affects lipid deposition, adipogensis, and adipokine secretion of human abdominal subcutaneous adipocytes. Mol. Metab., DOI: 10.1016/j.momet.2015.04.002 (2015)

Bonifacio, E., Ziegler, A.-G. , Klingensmith, G., Schober, E., Bingley, P.J., Rottenkolber, M., Theil, A., Eugster, A., Puff, R. , Peplow, C. , Buettner, F. , Lange, K., Hasford, J., Achenbach, P. °: Effects of high-dose oral insulin on immune responses in children at high risk for type 1 diabetes: The Pre-POINT randomized clinical trial. JAMA 313, 1541-1549 (2015)

Clemmensen, C. , Müller, T.D. , Finan, B. , Tschöp, M.H. °, DiMarchi, R.: Current and emerging treatment options in diabetes care. Handb. Exp. Pharmacol., DOI: 10.1007/164_2015_7 (2015)

Clemmensen, C. , Finan, B. , Fischer, K. , Tom, R.Z. , Legutko, B. , Sehrer, L. , Heine, D. , Grassl, N. , Meyer, C.W. , Henderson, B., Hofmann, S.M. , Tschöp, M.H. , van der Ploeg, L.H.T., Müller, T.D. °: Dual melanocortin-4 receptor and GLP-1 receptor agonism amplifies metabolic benefits in diet-induced obese mice. EMBO Mol. Med. 7, 288-298 (2015)

Diakopoulos, K.N., Lesina, M., Wörmann, S., Song, L., Aichler, M. , Schild, L., Artati, A. , Römisch-Margl, W., Wartmann, T., Fischer, R., Kabiri, Y. , Zischka, H. , Halangk, W., Demir, I.E., Pilsak, C., Walch, A.K. , Mantzoros, C.S., Steiner, J.M., Erkan, M., Schmid, R.M., Witt, H., Adamski, J. , Algül, H.°: Impaired autophagy induces chronic atrophic pancreatitis in mice via sex- and nutrition-dependent processes. Gastroenterology 148, 626-638 (2015) [published online 2014]

Dinter, J.#, Mühlhaus, J.#, Wienchol, C.L., Yi, C.-X., Nürnberg, D., Morin, S. , Grüters, A., Köhrle, J., Schöneberg, T., Tschöp, M.H., Krude, H., Kleinau, G., Biebermann, H.°: Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5. PLoS ONE 10:e0117774 (2015)

Ferrari, U. , Künzel, H.E.°, Tröndle, K. , Rottenkolber, M., Kohn, D., Fugmann, M. , Banning, F. , Weise, M. , Sacco, V. , Hasbargen, U., Hutter, S., Parhofer, K.G. , Kloiber, S., Ising, M., Seissler, J. , Lechner, A. : Poor sleep quality is associated with impaired glucose tolerance in women after gestational diabetes. J. Psychiatr. Res., DOI: 10.1016/j.jpsychires.2015.02.012 (2015)

Herder, C.°, Ouwens, D.M., Carstensen, M., Kowall, B., Huth, C. , Meisinger, C. , Rathmann, W., Roden, M., Thorand, B. : Adiponectin may mediate the association between omentin, circulating lipids and insulin sensitivity: Results from the KORA F4 study. Eur. J. Endocrinol. 172, 423-432 (2015)


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Huan, T.#, Esko, T.#, Peters, M.J.#, Pilling, L.C.#, Schramm, K. #, Schurmann, C.#, Chen, B.H., Liu, C., Joehanes, R., Johnson, A.D., Yao, C., Ying, S.X., Courchesne, P., Milani, L., Raghavachari, N., Wang, R., Liu, P., Reinmaa, E., Dehghan, A., Hofman, A., Uitterlinden, A.G., Hernandez, D.G., Bandinelli, S., Singleton, A., Melzer, D., Metspalu, A., Carstensen, M., Grallert, H. , Herder, C., Meitinger, T. , Peters, A. , Roden, M., Waldenberger, M. , Dörr, M., Felix, S.B., Zeller, T., ICBP Consortium (Levy, D.°), Vasan, R.S., O'Donnell, C.J., Munson, P.J., Yang, X.°, Prokisch, H. °, Völker, U.°, van Meurs, J.B.°, Ferrucci, L.°: A meta-analysis of gene expression signatures of blood pressure and hypertension. PLoS Genet. 11:e1005035 (2015)

Kälin, S. , Heppner, F.L., Bechmann, I., Prinz, M., Tschöp, M.H. °, Yi, C.X.: Hypothalamic innate immune reaction in obesity. Nat. Rev. Endocrinol., DOI: 10.1038/nrendo.2015.48 (2015)

Karbiener, M. , Scheideler, M. °: Microarray analysis of small non-coding RNAs. Methods Mol. Biol. 1296, 161-171 (2015)

Kluth, O. , Matzke, D. , Schulze, G. , Schwenk, R.W. , Joost, H.-G. , Schürmann, A.: Differential transcriptome analysis of diabetes-resistant and -sensitive mouse islets reveals significant overlap with human diabetes susceptibility genes. Diabetes 63, 4230-4238 (2014)

Koch, M., Baurecht, H., Ried, J.S. , Rodriguez, E., Schlesinger, S., Volks, N., Gieger, C. , Rückert, I.-M. , Heinrich, L., Willenborg, C., Smith, C., Peters, A. , Thorand, B. , Koenig, W., Lamina, C., Jansen, H., Kronenberg, F., Seissler, J., Thiery, J., Rathmann, W., Schunkert, H., Erdmann, J., Barker, J., Nair, R.P., Tsoi, L.C., Elder, J.T., Mrowietz, U., Weichenthal, M., Mucha, S., Schreiber, S., Franke, A., Schmitt, J., Lieb, W., Weidinger, S.°: Psoriasis and cardiometabolic traits: Modest association but distinct genetic architectures. J. Invest. Dermatol. 135, 1283-1293 (2015)

Kong, B., Wu, W., Cheng, T., Schlitter, A.M., Qian, C., Bruns, P. , Jian, Z., Jager, C., Regel, I., Raulefs, S., Behler, N., Irmler, M. , Beckers, J. , Friess, H., Erkan, M., Siveke, J.T., Tannapfel, A., Hahn, S.A., Theis, F.J., Esposito, I., Kleeff, J., Michalski, C.W.°: A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling. Gut, DOI: 10.1136/gutjnl-2014-307616 (2015)


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Mahajan, A.#, Sim, X.#, Ng, H.J.#, Manning, A., Rivas, M.A., Highland, H.M., Locke, A.E., Grarup, N., Im, H.K., Cingolani, P., Flannick, J., Fontanillas, P., Fuchsberger, C., Gaulton, K.J., Teslovich, T.M., Rayner, N.W., Robertson, N.R., Beer, N.L., Rundle, J.K., Bork-Jensen, J., Ladenvall, C., Blancher, C., Buck, D., Buck, G., Burtt, N.P., Gabriel, S., Gjesing, A.P., Groves, C.J., Hollensted, M., Huyghe, J.R., Jackson, A.U., Jun, G., Justesen, J.M., Mangino, M., Murphy, J., Neville, M., Onofrio, R., Small, K.S., Stringham, H.M., Syvanen, A.C., Trakalo, J., Abecasis, G., Bell, G.I., Blangero, J., Cox, N.J., Duggirala, R., Hanis, C.L., Seielstad, M., Wilson, J.G., Christensen, C., Brandslund, I., Rauramaa, R., Surdulescu, G.L., Doney, A.S., Lannfelt, L., Linneberg, A., Isomaa, B., Tuomi, T., Jørgensen, M.E., Jørgensen, T., Kuusisto, J., Uusitupa, M., Salomaa, V., Spector, T.D., Morris, A.D., Palmer, C.N., Collins, F.S., Mohlke, K.L., Bergman, R.N., Ingelsson, E., Lind, L., Tuomilehto, J., Hansen, T., Watanabe, R.M., Prokopenko, I., Dupuis, J., Karpe, F., Groop, L., Laakso, M., Pedersen, O., Florez, J.C., Morris, A.P., Altshuler, D., Meigs, J.B., Boehnke, M., McCarthy, M.I., Lindgren, C.M.°, Gloyn, A.L.°, T2D-GENES Consortium, GoT2D Consortium (Hrabě de Angelis, M. , Gieger, C. , Grallert, H. , Huth, C. , Kriebel, J. , Meisinger, C. , Meitinger, T. , Peters, A. , Ried, J.S., Strauch, K. , Strom, T.-M. ), GoT2D Consortium (Müller-Nurasyid, M. ): Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus. PLoS Genet. 11:e1004876 (2015)

Medrikova, D., Sijmonsma, T.P., Sowodniok, K., Richards, D.M., Delacher, M., Sticht, C., Gretz, N., Schafmeier, T. , Feuerer, M., Herzig, S. °: Brown adipose tissue harbors a distinct sub-population of regulatory T cells. PLoS ONE 10:e0118534 (2015)

Moutsianas, L.#°, Agarwala, V.#, Fuchsberger, C., Flannick, J., Rivas, M.A., Gaulton, K.J., Albers, P.K., GoT2D Consortium (McCarthy, M.I.°, Gieger, C. ), GoT2D Consortium (Grallert, H. , Huth, C. , Kriebel, J. , Meisinger, C. , Meitinger, T. , Müller-Nurasyid, M. , Peters, A. , Ried, J.S. , Strauch, K. , Strom, T.-M. ), McVean, G., Boehnke, M., Altshuler, D.: The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease. PLoS Genet. 11:e1005165 (2015)

Müller, T.D. , Nogueiras, R.A., Andermann, M.L., Andrews, Z.B., Anker, S.D., Argente, J., Batterham, R., Benoit, S.C., Bowers, C.Y., Broglio, F., Casanueva, F.F.F., D'Alessio, D., Depoortere, I., Geliebter, A.A., Ghigo, E., Cole, P.A., Cowley, M.A., Cummings, D.E., Dagher, A., Diano, S., Dickson, S.L., Dieguez, C., Granata, R., Grill, H.J., Grove, K.L., Habegger, K.M., Heppner, K.M., Heiman, M.L., Holsen, L., Holst, B., Inui, A., Jansson, J.O., Kirchner, H., Korbonits, M., Laferrère, B., LeRoux, C.W., López, M.D., Morin, S. , Nakazato, M., Nass, R., Perez-Tilve, D., Pfluger, P.T. , Schwartz, T.W., Seeley, R.J., Sleeman, M.W., Sun, Y., Sussel, L., Tong, J., Thorner, M.O., van der Lely, A.J., van der Ploeg, L.H.T., Zigman, J.M., Kojima, M., Kangawa, K., Smith, R.G., Horvath, T., Tschöp, M.H. °: Ghrelin. Mol. Metab., DOI: 10.1016/j.molmet.2015.03.005 (2015)

Müller, T.D. °: The potential of glucagon-like peptide 1 to reverse high-fat, high-sugar diet-related metabolic damage. Expert Rev. Endocrinol. Metab. 9, 293-295 (2014)


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Pfeiffer, L. , Wahl, S. , Pilling, L.C., Reischl, E. , Sandling, J.K., Kunze, S. , Holdt, L.M., Kretschmer, A. , Schramm, K. , Adamski, J. , Klopp, N., Illig, T., Hedman, A.K., Roden, M., Hernandez, D.G., Singleton, A.B., Thasler, W.E., Grallert, H. , Gieger, C. , Herder, C., Teupser, D., Meisinger, C. , Spector, T.D., Kronenberg, F., Prokisch, H. , Melzer, D., Peters, A. , Deloukas, P., Ferrucci, L., Waldenberger, M. °: DNA methylation of lipid-related genes affects blood lipid levels. Circ. Cardiovasc. Genet. 8, 334-342 (2015)

Reis, W.L. , Yi, C.-X., Gao, Y., Tschöp, M.H. , Stern, J.E.°: Brain innate immunity regulates hypothalamic arcuate neuronal activity and feeding behavior. Endocrinology 156, 1303-1315 (2015)

Rottenkolber, M.#, Ferrari, U. #, Holland, L. , Aertsen, S. , Kammer, N.N., Hetterich, H., Fugmann, M. , Banning, F. , Weise, M. , Sacco, V. , Kohn, D., Freibothe, I. , Hutter, S., Hasbargen, U., Lehmann, R., Grallert, H. , Parhofer, K.G., Seissler, J. , Lechner, A. °: The diabetes risk phenotype of young women with recent gestational diabetes. J. Clin. Endocrinol. Metab., DOI: 10.1210/jc.2014-3898 (2015)

Sartorius, T. °, Drescher, A., Panse, M., Lastovicka, P., Peter, A., Weigert, C. , Kostenis, E., Ullrich, S., Häring, H.-U. : Mice lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are protected against conjugated linoleic acid-induced fatty liver but develop inflammation and insulin resistance in the brain. Cell. Physiol. Biochem. 35, 2272-2284 (2015)

Scheler, M. , Hrabě de Angelis, M. , Al-Hasani, H., Häring, H.-U. , Weigert, C. °, Lehr, S.: Methods for proteomics-based analysis of the human muscle secretome using an in vitro exercise model. Methods Mol. Biol. 1295, 55-64 (2015)

Schunk, M. °, Stark, R.G. , Reitmeir, P. , Meisinger, C. , Holle, R. : Towards patient-oriented diabetes care: Results from two KORA surveys in Southern Germany: J. Diabetes Res. 2015:368570 (2015)

Segrè, A.V., Wei, N., DIAGRAM Consortium (Altshuler, D. , Florez, J.C. °, Klopp, N.B. , Illig, T. , Müller-Nurasyid, M. , Peters, A. ): Pathways targeted by antidiabetes drugs are enriched for multiple genes associated with type 2 diabetes risk. Diabetes 64, 1470-1483 (2015)

Shariful Islam, S.M.°, Lechner, A., Ferrari, U., Seissler, J., Holle, R. , Niessen, L.W.: Mobile phone use and willingness to pay for SMS for diabetes in Bangladesh. J. Public Health, DOI: 10.1093/pubmed/fdv009 (2015)


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Swerdlow, D.I.#, Preiss, D.#, Kuchenbaecker, K.B., Holmes, M.V., Engmann, J.E.L., Shah, T., Sofat, R., Stender, S., Johnson, P.C.D., Scott, R.A., Leusink, M., Verweij, N., Sharp, S.J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J., Howard, P., Cooper, J.A., Drenos, F., Li, Y.R., Lowe, G., Gallacher, J., Stewart, M.C.W., Tzoulaki, I., Buxbaum, S.G., Daphne, L.v.d.A., Forouhi, N.G., Onland-Moret, N.C., van der Schouw, Y.T., Schnabel, R.B., Hubácek, J.A., Kubínová, R., Baceviciene, M., Tamosiunas, A., Pajak, A., Topor-Madry, R., Stepaniak, U., Malyutina, S.A., Baldassarre, D., Sennblad, B., Tremoli, E., de Faire, U., Veglia, F., Ford, I., Jukema, J.W., Westendorp, R.G.J., de Borst, G.J., De Jong, P.A., Algra, A., Spiering, W., Maitland-van der Zee, A.H., Klungel, O.H., de Boer, A., Doevendans, P.A., Eaton, C.B., Robinson, J.G., Duggan, D., Kjekshus, J., Downs, J.R., Gotto, A.M., Keech, A.C., Marchioli, R., Tognoni, G., Sever, P.S., Poulter, N.R., Waters, D.D., Pedersen, T.R., Amarenco, P., Nakamura, H., McMurray, J.J.V., Lewsey, J.D., Chasman, D.I., Ridker, P.M., Maggioni, A.P., Tavazzi, L., Ray, K.K., Seshasai, S.R.K., Manson, J.E., Price, J.F., Whincup, P.H., Morris, R.W., Lawlor, D.A., Smith, G.D., Ben-Shlomo, Y., Schreiner, P.J., Fornage, M., Siscovick, D.S., Cushman, M., Kumari, M., Wareham, N.J., Verschuren, W.M.M., Redline, S., Patel, S.R., Whittaker, J.C., Hamsten, A., Delaney, J.A., Dale, C.E., Gaunt, T.R., Wong, A., Kuh, D., Hardy, R., Kathiresan, S., Castillo, B.A., van der Harst, P., Brunner, E.J., Tybjaerg-Hansen, A., Marmot, M.G., Krauss, R.M., Tsai, M., Coresh, J., Hoogeveen, R.C., Psaty, B.M., Lange, L.A., Hakonarson, H., Dudbridge, F., Humphries, S.E., Talmud, P.J., Kivimaeki, M., Timpson, N.J., Langenberg, C., Asselbergs, F.W., Voevoda, M., Bobak, M., Pikhart, H., Wilson, J.G., Reiner, A.P., Keating, B.J., Hingorani, A.D.°, Sattar, N.°, DIAGRAM Consortium (Grallert, H. , Gieger, C. , Klopp, N.B. , Illig, T. , Müller-Nurasyid, M. , Peters, A. ), MAGIC Consortium (Meisinger, C. , Thorand, B. , Wichmann, H.-E. ), InterAct Consortium: HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials. Lancet 385, 351-361 (2015)

Tönjes, A.#, Scholz, M.#, Breitfeld, J., Marzi, C. , Grallert, H. , Gross, A., Ladenvall, C., Schleinitz, D., Krause, K.P., Kirsten, H., Laurila, E., Kriebel, J. , Thorand, B. , Rathmann, W., Groop, L.C., Prokopenko, I., Isomaa, B., Beutner, F., Kratzsch, J.K., Thiery, J.J., Faßhauer, M., Klöting, N., Gieger, C. , Blüher, M., Stumvoll, M.W.°, Kovacs, P.°: Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. PLoS Genet. 10:e1004854 (2015)

Wahl, S. #°, Vogt, S.#, Stückler, F. , Krumsiek, J. , Bartel, J. , Kacprowski, T., Schramm, K. , Carstensen, M., Rathmann, W., Roden, M., Jourdan, C. , Kangas, A.J., Soininen, P., Ala-Korpela, M., Nöthlings, U., Boeing, H., Theis, F.J. , Meisinger, C. , Waldenberger, M. , Suhre, K. , Homuth, G., Gieger, C. , Kastenmüller, G. , Illig, T. , Linseisen, J. , Peters, A. , Prokisch, H. , Herder, C. , Thorand, B. °, Grallert, H. °: Multi-omic signature of body weight change: Results from a population-based cohort study. BMC Med. 13:48 (2015)

Walter, M.C. #, Öhrman, C.#, Myrtennäs, K., Sjödin, A., Byström, M., Larsson, P., Macellaro, A., Forsman, M.#, Frangoulidis, D.#°: Genome sequence of Coxiella burnetii strain Namibia. Stand. Genomic Sci. 9:22 (2014)

Weber, S. , Salabei, J.K., Möller, G. , Kremmer, E. , Bhatnagar, A., Adamski, J. °, Barski, O.A.°: Aldo-Keto Reductase 1B15 (AKR1B15): A mitochondrial human aldo-keto reductase with activity toward steroids and 3-keto-acyl-CoA conjugates. J. Biol. Chem. 290, 6531-6545 (2015)


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Westra, H.J.#, Arends, D.#, Esko, T., Peters, M.J., Schurmann, C., Schramm, K. , Kettunen, J., Yaghootkar, H., Fairfax, B.P., Andiappan, A.K., Li, Y., Fu, J., Karjalainen, J., Platteel, M., Visschedijk, M., Weersma, R.K., Kasela, S., Milani, L., Tserel, L., Peterson, P., Reinmaa, E., Hofman, A., Uitterlinden, A.G., Rivadeneira, F., Homuth, G., Petersmann, A., Lorbeer, R., Prokisch, H. , Meitinger, T. , Herder, C., Roden, M., Grallert, H. , Ripatti, S., Perola, M., Wood, A.R., Melzer, D., Ferrucci, L., Singleton, A.B., Hernandez, D.G., Knight, J.C., Melchiotti, R., Lee, B., Poidinger, M., Zolezzi, F., Larbi, A., Wang, Y., van den Berg, L.H., Veldink, J.H., Rotzschke, O., Makino, S., Salomaa, V., Strauch, K. , Völker, U., van Meurs, J.B., Metspalu, A., Wijmenga, C., Jansen, R.C., Franke, L.°: Cell specific eQTL analysis without sorting cells. PLoS Genet. 11:e1005223 (2015)

Wittenbecher, C., Mühlenbruch, K., Kröger, J., Jacobs, S., Kuxhaus, O., Floegel, A., Fritsche, A., Pischon, T., Prehn, C. , Adamski, J. , Joost, H.-G., Boeing, H., Schulze, M.B.°: Amino acids, lipid metabolites, and ferritin as potential mediators linking red meat consumption to type 2 diabetes. Am. J. Clin. Nutr., DOI: 10.3945/ajcn.114.099150 (2015)

Würtz, P.°, Havulinna, A.S., Soininen, P., Tynkkynen, T., Prieto-Merino, D., Tillin, T., Ghorbani, A., Artati, A. , Wang, Q., Tiainen, M., Kangas, A.J., Kettunen, J., Kaikkonen, J., Mikkilä, V., Jula, A., Kähönen, M., Lehtimäki, T., Lawlor, D.A., Gaunt, T.R., Hughes, A.D., Sattar, N., Illig, T. , Adamski, J. , Wang, T.J., Perola, M., Ripatti, S., Vasan, R.S., Raitakari, O.T., Gerszten, R.E., Casas, J.P., Chaturvedi, N., Ala-Korpela, M., Salomaa, V.: Metabolite profiling and cardiovascular event risk: A prospective study of three population-based cohorts. Circulation 131, 774-785 (2015)


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Huber, M.B. °, Wacker, M. , Vogelmeier, C.F., Leidl, R. : Excess costs of comorbidities in chronic obstructive pulmonary disease: A systematic review. PLoS ONE 10:e0123292 (2015)

Kirsch, F. °: A systematic review of quality and cost-effectiveness derived from Markov models evaluating smoking cessation interventions in patients with chronic obstructive pulmonary disease. Expert Rev. Pharmacoecon. Outcomes Res. 15, 301-316 (2015)


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Boyman, O.°, Kaegi, C., Akdis, M., Bavbek, S., Bossios, A., Chatzipetrou, A., Eiwegger, T., Firinu, D., Harr, T., Knol, E., Matucci, A., Palomares, O., Schmidt-Weber, C.B. , Simon, H.U., Steiner, U.C., Vultaggio, A., Akdis, C.A., Spertini, F.: EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders. Allergy, DOI: 10.1111/all.12616 (2015)

Esser-von Bieren, J. , Volpe, B., Sutherland, D.B., Bürgi, J., Verbeek, J.S., Marsland, B.J., Urban, J.F., Harris, N.L.°: Immune antibodies and helminth products drive CXCR2-dependent macrophage-myofibroblast crosstalk to promote intestinal repair. PLoS Pathog. 11:e1004778 (2015)

Eyerich, K.°, Eyerich, S. : Th22-Zellen bei allergischen Erkrankungen. Allergo J. 24, 17-23 (2015)

Eyerich, S. °: Molekulare Signaturen zur besseren Unterscheidung : Psoriasis und Ekzem - was wir von doppelt betroffenen Patienten lernen können. Haut 26, 24-30 (2015)

Gilles, S.°, Beck, I., Lange, S., Ring, J., Behrendt, H. , Traidl-Hoffmann, C.: Non-allergenic factors from pollen modulate T helper cell instructing notch ligands on dendritic cells. World Allergy Organiz. J. 8:2 (2015)

Krämer, U.°, Schmitz, R., Ring, J., Behrendt, H. °: What can reunification of East and West Germany tell us about the cause of the allergy epidemic? Clin. Exp. Allergy 45, 94-107 (2014)

Möbs, C.#, Müller, J.#, Rudzio, A., Pickert, J., Blank, S. , Jakob, T., Spillner, E., Pfützner, W.°: Decline of Ves v 5-specific blocking capacity in wasp venom-allergic patients after stopping allergen immunotherapy. Allergy, DOI: 10.1111/all.12606 (2015)

Oteros, J. °, Garcia-Mozo, H., Alcázar, P., Belmonte, J., Bermejo, D., Boi, M., Cariñanos, P., Díaz de la Guardia, C., Fernández-González, D., González-Minero, F., Gutiérrez-Bustillo, A.M., Moreno-Grau, S., Pérez-Badía, R., Rodríguez-Rajo, F.J., Ruíz-Valenzuela, L., Suárez-Pérez, J., Trigo, M.M., Domínguez-Vilches, E., Galan, C.: A new method for determining the sources of airborne particles. J. Environ. Manage. 155, 212-218 (2015)

Rosewich, M.°, Zissler, U.M. , Kheiri, T., Voss, S., Eickmeier, O., Schulze, J., Herrmann, E., Dücker, R.P., Schubert, R., Zielen, S.: Airway inflammation in children and adolescents with bronchiolitis obliterans. Cytokine 73, 156-162 (2015)

Wimmer, M. #, Alessandrini, F. #°, Gilles, S., Frank, U. , Oeder, S. , Hauser, M., Ring, J., Ferreira, F., Ernst, D., Winkler, J.B. , Schmitt-Kopplin, P. , Ohnmacht, C., Behrendt, H. , Schmidt-Weber, C.B. , Traidl-Hoffmann, C., Gutermuth, J. : Pollen-derived adenosine is a necessary co-factor for ragweed allergy. Allergy, DOI: 10.1111/all.12642 (2015)


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Dehghany, J.°, Hoboth, P. , Ivanova, A. , Mziaut, H. , Müller, A. , Kalaidzidis, Y., Solimena, M. , Meyer-Hermann, M.: A spatial model of insulin-granule dynamics in pancreatic β-cells. Traffic, DOI: 10.1111/tra.12286 (2015)

Hoboth, P. , Müller, A. , Ivanova, A. , Mziaut, H. , Dehghany, J., Sönmez, A. , Lachnit, M. , Meyer-Hermann, M., Kalaidzidis, Y., Solimena, M. °: Aged insulin granules display reduced microtubule-dependent mobility and are disposed within actin-positive multigranular bodies. Proc. Natl. Acad. Sci. U.S.A. 112, E667-E676 (2015)

Kaszuba, K.#, Grzybek, M. #, Orłowski, A., Danne, R., Róg, T., Simons, K.°, Coskun, Ü. °, Vattulainen, I.°: N-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes. Proc. Natl. Acad. Sci. U.S.A. 112, 4334–4339 (2015)

Lenoir, M., Grzybek, M. , Majkowski, M., Rajesh, S., Kaur, J., Whittaker, S.B., Coskun, Ü. , Overduin, M.°: Structural basis of dynamic membrane recognition by trans-Golgi network specific FAPP proteins. J. Mol. Biol. 427, 966-981 (2015)

Sezgin, E., Gutmann, T. , Buhl, T., Dirkx, R. , Grzybek, M. , Coskun, Ü. , Solimena, M. , Simons, K., Levental, I.°, Schwille, P.°: Adaptive lipid packing and bioactivity in membrane domains. PLoS ONE 10:e0123930 (2015)


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Shungin, D., Winkler, T.W., Croteau-Chonka, D.C., Ferreira, T., Locke, A.E., Mägi, R., Strawbridge, R.J., Pers, T.H., Fischer, K., Justice, A.E., Workalemahu, T., Wu, J.M., Buchkovich, M.L., Heard-Costa, N.L., Roman, T.S., Drong, A.W., Song, C., Gustafsson, S., Day, F.R., Esko, T., Fall, T., Kutalik, Z., Luan, J., Randall, J.C., Scherag, A., Vedantam, S., Wood, A.R., Chen, J., Fehrmann, R.S.N., Karjalainen, J., Kahali, B., Liu, C.T., Schmidt, E.M., Absher, D., Amin, N., Anderson, D., Beekman, M., Bragg-Gresham, J.L., Buyske, S., Demirkan, A., Ehret, G.B., Feitosa, M.F., Goel, A., Jackson, A.U., Johnson, T., Kleber, M.E., Kristiansson, K., Mangino, M., Mateo Leach, I., Medina-Gomez, C., Palmer, C.D., Pasko, D., Pechlivanis, S., Peters, M.J., Prokopenko, I., Stancáková, A., Ju Sung, Y., Tanaka, T., Teumer, A., van Vliet-Ostaptchouk, J.V., Yengo, L., Zhang, W., Albrecht, E. , Ärnlöv, J., Arscott, G.M., Bandinelli, S., Barrett, A., Bellis, C., Bennett, A.J., Berne, C., Blüher, M., Böhringer, S., Bonnet, F., Böttcher, Y., Bruinenberg, M., Carba, D.B., Caspersen, I.H., Clarke, R., Daw, E.W., Deelen, J., Deelman, E., Delgado, G., Doney, A.S., Eklund, N., Erdos, M.R., Estrada, K., Eury, E., Friedrich, N., Garcia, M.E., Giedraitis, V., Gigante, B., Go, A.S., Golay, A., Grallert, H. , Grammer, T.B., Gräßler, J., Grewal, J., Groves, C.J., Haller, T., Hallmans, G., Hartman, C.A., Hassinen, M., Hayward, C., Heikkilä, K., Herzig, K.H., Helmer, Q., Hillege, H.L., Holmen, O.L., Hunt, S.C., Isaacs, A., Ittermann, T., James, A.L., Johansson, I., Juliusdottir, T., Kalafati, I.P., Kinnunen, L., Koenig, W., Kooner, I.K., Kratzer, W., Lamina, C., Leander, K., Lee, N.R., Lichtner, P. , Lind, L., Lindstrom, J., Lobbens, S., Lorentzon, M., Mach, F., Magnusson, P.K., Mahajan, A., McArdle, W.L., Menni, C., Merger, S., Mihailov, E., Milani, L., Mills, R., Moayyeri, A., Monda, K.L., Mooijaart, S.P., Mühleisen, T.W., Mulas, A., Müller, G., Müller-Nurasyid, M. , Nagaraja, R., Nalls, M.A., Narisu, N., Glorioso, N., Nolte, I.M., Olden, M., Rayner, N.W., Renström, F., Ried, J.S. , Robertson, N.R., Rose, L.M., Sanna, S., Scharnagl, H., Scholtens, S., Sennblad, B., Seufferlein, T., Sitlani, C.M., Smith, A.V., Stirrups, K., Stringham, H.M., Sundström, J., Swertz, M.A., Swift, A.J., Syvanen, A.C., Tayo, B.O., Thorand, B. , Thorleifsson, G., Tomaschitz, A., Troffa, C., van Oort, F.V., Verweij, N., Vonk, J.M., Waite, L.L., Wennauer, R., Wilsgaard, T., Wojczynski, M.K., Wong, A., Zhang, Q., Hua Zhao, J., Brennan, E.P., Choi, M., Eriksson, P., Folkersen, L., Franco-Cereceda, A., Gharavi, A.G., Hedman, A.K., Hivert, M.F., Huang, J., Kanoni, S., Karpe, F., Keildson, S., Kiryluk, K., Liang, L., Lifton, R.P., Ma, B., McKnight, A.J., McPherson, R., Metspalu, A., Min, J.L., Moffatt, M.F., Montgomery, G.W., Murabito, J.M., Nicholson, G., Nyholt, D.R., Olsson, C., Perry, J.R., Reinmaa, E., Salem, R.M., Sandholm, N., Schadt, E.E., Scott, R.A., Stolk, L., Vallejo, E.E., Westra, H.J., Zondervan, K.T., Amouyel, P., Arveiler, D., Bakker, S.J., Beilby, J., Bergman, R.N., Blangero, J., Brown, M.J., Burnier, M., Campbell, H., Chakravarti, A., Chines, P.S., Claudi-Boehm, S., Collins, F.S., Crawford, D.C., Danesh, J., de Faire, U., de Geus, E.J., Dörr, M., Erbel, R., Eriksson, J.G., Farrall, M., Ferrannini, E., Ferrieres, J., Forouhi, N.G., Forrester, T., Franco, O.H., Gansevoort, R.T., Gieger, C. , Gudnason, V., Haiman, C.A., Harris, T.B., Hattersley, A.T., Heliövaara, M., Hicks, A.A., Hingorani, A.D., Hoffmann, W., Hofman, A., Homuth, G., Humphries, S.E., Hyppönen, E., Illig, T. , Jarvelin, M.R., Johansen, B., Jousilahti, P., Jula, A.M., Kaprio, J., Kee, F., Keinanen-Kiukaanniemi, S.M., Kooner, J.S., Kooperberg, C., Kovacs, P., Kraja, A.T., Kumari, M., Kuulasmaa, K., Kuusisto, J., Lakka, T.A., Langenberg, C., Le Marchand, L., Lehtimäki, T., Lyssenko, V., Männisto, S., Marette, A., Matise, T.C., McKenzie, C.A., McKnight, B., Musk, A.W., Möhlenkamp, S., Morris, A.D., Nelis, M., Ohlsson, C., Oldehinkel, A.J., Ong, K.K., Palmer, L.J., Penninx, B.W., Peters, A. , Pramstaller, P.P., Raitakari, O.T., Rankinen, T., Rao, D.C., Rice, T.K., Ridker, P.M., Ritchie, M.D., Rudan, I., Salomaa, V., Samani, N.J., Saramies, J., Sarzynski, M.A., Schwarz, P.E., Shuldiner, A.R., Staessen, J.A., Steinthorsdottir, V., Stolk, R.P., Strauch, K., Tönjes, A., Tremblay, A., Tremoli, E., Vohl, M.C., Völker, U., Vollenweider, P., Wilson, J.F., Witteman, J.C., Adair, L.S., Bochud, M., Boehm, B.O., Bornstein, S.R., Bouchard, C., Cauchi, S., Caulfield, M.J.,


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Chambers, J.C., Chasman, D.I., Cooper, R.S., Dedoussis, G., Ferrucci, L., Froguel, P., Grabe, H.J., Hamsten, A., Hui, J., Hveem, K., Jockel, K.H., Kivimaki, M., Kuh, D., Laakso, M., Liu, Y., Marz, W., Munroe, P.B., Njølstad, I., Oostra, B.A., Palmer, C.N., Pedersen, N.L., Perola, M., Perusse, L., Peters, U., Power, C., Quertermous, T., Rauramaa, R., Rivadeneira, F., Saaristo, T.E., Saleheen, D., Sinisalo, J., Slagboom, P.E., Snieder, H., Spector, T.D., Thorsteinsdottir, U., Stumvoll, M., Tuomilehto, J., Uitterlinden, A.G., Uusitupa, M., van der Harst, P., Veronesi, G., Walker, M., Wareham, N.J., Watkins, H., Wichmann, H.-E. , Abecasis, G.R., Assimes, T.L., Berndt, S.I., Boehnke, M., Borecki, I.B., Deloukas, P., Franke, L., Frayling, T.M., Groop, L.C., Hunter, D.J., Kaplan, R.C., O'Connell, J.R., Qi, L., Schlessinger, D., Strachan, D.P., Stefansson, K., van Duijn, C.M., Willer, C.J., Visscher, P.M., Yang, J., Hirschhorn, J.N., Zillikens, M.C., McCarthy, M.I., Speliotes, E.K., North, K.E., Fox, C.S., Barroso, I., Franks, P.W., Ingelsson, E., Heid, I.M. , Loos, R.J., Cupples, L.A., Morris, A.P., Lindgren, C.M.°, Mohlke, K.L.°: New genetic loci link adipose and insulin biology to body fat distribution. Nature 518, 187-196 (2015)

Steck, A.K.°, Vehik, K., Bonifacio, E. , Lernmark, A., Ziegler, A.-G. , Hagopian, W.A., She, J., Simell, O., Akolkar, B., Krischer, J., Schatz, D., Rewers, M.J., TEDDY Study Group (Beyerlein, A. , Hummel, M. , Hummel, S. , Foterek, K. , Kersting, M. , Knopff, A. , Koletzko, S. , Peplow, C. , Roth, R. , Stock, J. , Strauss, E., Warncke, K. , Winkler, C. ): Predictors of progression from the appearance of islet autoantibodies to early childhood diabetes: The Environmental Determinants of Diabetes in the Young (TEDDY). Diabetes Care 38, 808-813 (2015)


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Scheler, C. , Weitbrecht, K., Pearce, S.P., Hampstead, A., Büttner-Mainik, A., Lee, K.J.D., Voegele, A., Oracz, K., Dekkers, B.J.W., Wang, X., Wood, A.T.A., Bentsink, L., King, J.R., Knox, J.P., Holdsworth, M.J., Müller, K.B., Leubner-Metzger, G.°: Promotion of testa rupture during garden cress germination involves seed compartment-specific expression and activity of pectin methylesterases. Plant Physiol. 167, 200-215 (2015)

Velikova, V.B. , Müller, C. , Ghirardo, A. , Rock, T. , Aichler, M. , Walch, A.K. , Schmitt-Kopplin, P. , Schnitzler, J.-P. °: Knocking down of isoprene emission modifies the lipid matrix of thylakoid membranes and influences the chloroplast ultrastructure in poplar. Plant Physiol., DOI: 10.1104/pp.15.00612 (2015)

Wimmer, M. #, Alessandrini, F. #°, Gilles, S., Frank, U. , Oeder, S. , Hauser, M., Ring, J., Ferreira, F., Ernst, D., Winkler, J.B. , Schmitt-Kopplin, P. , Ohnmacht, C., Behrendt, H. , Schmidt-Weber, C.B. , Traidl-Hoffmann, C., Gutermuth, J. : Pollen-derived adenosine is a necessary co-factor for ragweed allergy. Allergy, DOI: 10.1111/all.12642 (2015)


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Anton, G. °, Wilson, R.K. , Yu, Z., Prehn, C. , Zukunft, S. , Adamski, J. , Heier, M. , Meisinger, M. , Römisch-Margl, W. , Wang-Sattler, R. , Hveem, K., Wolfenbuttel, B.H.R., Peters, A. , Kastenmüller, G. , Waldenberger, M. : Pre-analytical sample quality: Metabolite ratios as an intrinsic marker for prolonged room temperature exposure of serum samples. PLoS ONE 10:e0121495 (2015)


Haase, K., Raffegerst, S.H. , Schendel, D.J. , Frishman, D. °: Expitope: A web server for epitope expression. Bioinformatics, DOI: 10.1093/bioinformatics/btv068 (2015)

Kolder, I.C., Tanck, M.W., Postema, P.G., Barc, J., Sinner, M.F., Zumhagen, S., Husemann, A., Stallmeyer, B., Koopmann, T.T., Hofman, N., Pfeufer, A. , Lichtner, P. , Meitinger, T. , Beckmann, B.M., Myerburg, R.J., Bishopric, N.H., Roden, D.M., Kääb, S., Wilde, A.A., Schott, J.J., Schulze-Bahr, E., Bezzina, C.R.°: Analysis for genetic modifiers of disease severity in patients with long QT syndrome type 2. Circ. Cardiovasc. Genet., DOI: 10.1161/CIRCGENETICS.114.000785 (2015)

Kong, B., Bruns, P. , Raulefs, S., Rieder, S., Paul, L., da Costa, O.P., Buch, T., Theis, F.J. , Michalski, C.W., Kleeff, J.: Metabolism gene signatures and surgical site infections in abdominal surgery. Int. J. Surg. 14, 67-74 (2015)

Livshits, G., Macgregor, A.J., Gieger, C. , Malkin, I., Moayyeri, A., Grallert, H. , Emeny, R.T. , Spector, T., Kastenmüller, G. , Williams, F.M.: An omics investigation into chronic widespread musculoskeletal pain reveals epiandrosterone sulfate as a potential biomarker. Pain, DOI: 10.1097/j.pain.0000000000000200 (2015)

Mook-Kanamori, M.J., El-Din Selim, M.M., Takiddin, A.H., Al-Mahmoud, K.A.S., Al-Homsi, H., McKeon, C., Al Muftah, W.A., Kader, S.A., Mook-Kanamori, D.O., Suhre, K. °: Elevated HbA1c levels in individuals not diagnosed with type 2 diabetes in Qatar: A pilot study. Qatar Med. J. 2014:17 (2014)

Pfannmüller, A., Wagner, D., Sieber, C.M.K. , Schönig, B., Boeckstaens, M., Marini, A.M., Tudzynski, B.°: The general amino acid permease FfGap1 of Fusarium fujikuroi Is sorted to the vacuole in a nitrogen-dependent, but Npr1 kinase-independent manner. PLoS ONE 10:e0125487 (2015)

Schuler, D., Wahl, R., Wippel, K., Vranes, M., Münsterkötter, M. , Sauer, N., Kämper, J.T.°: Hxt1, a monosaccharide transporter and sensor required for virulence of the maize pathogen Ustilago maydis. New Phytol. 206, 1086-1100 (2015)

Schwab, S. , Zierer, A. , Schneider, A.E. , Heier, M. , Koenig, W., Kastenmüller, G. , Waldenberger, M. , Peters, A. , Thorand, B. °: Vitamin E supplementation is associated with lower levels of C-reactive protein only in higher dosages and combined with other antioxidants: The Cooperative Health Research in the Region of Augsburg (KORA) F4 study. Br. J. Nutr., DOI: 10.1017/S0007114515000902 (2015)


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Widmann, P., Reverter, A., Weikard, R., Suhre, K. , Hammon, H.M., Albrecht, E., Kuehn, C.°: Systems biology analysis merging phenotype, metabolomic and genomic data identifies Non-SMC Condensin I Complex, Subunit G (NCAPG) and cellular maintenance processes as major contributors to genetic variability in bovine feed efficiency. PLoS ONE 10:e0124574 (2015)

Zach, N.°, Ennist, D.L., Taylor, A.A., Alon, H., Sherman, A.V., Küffner, R. , Walker, J., Sinani, E., Katsovskiy, I., Cudkowicz, M.E., Leitner, M.L.: Being PRO-ACTive: What can a clinical trial database reveal about ALS? Neurotherapeutics 12, 417-423 (2015)

Zaghlool, S.B., Al-Shafai, M., Al Muftah, W.A., Kumar, P., Falchi, M., Suhre, K. °: Association of DNA methylation with age, gender, and smoking in an Arab population. Clin. Epigenet. 7:6 (2015)


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Assmann, W.°, Kellnberger, S. , Reinhardt, S., Lehrack, S., Edlich, A., Thirolf, P.G., Moser, M., Dollinger, G., Omar, M. , Ntziachristos, V. , Parodi, K.: Ionoacoustic characterization of the proton Bragg peak with submillimeter accuracy. Med. Phys. 42, 567-574 (2015)

Attia, A.B.E., Balasundaram, G., Driessen, W.H.P. , Ntziachristos, V. , Olivo, M.°: Phthalocyanine photosensitizers as contrast agents for in vivo photoacoustic tumor imaging. Biomed. Opt. Express 6, 591-598 (2015)

Azimzadeh, O. °, Sievert, W. , Sarioglu, H. , Merl-Pham, J. , Yentrapalli, R. , Bakshi, M.V. , Janik, D. , Ueffing, M. , Atkinson, M.J. , Multhoff, G. , Tapio, S. : Integrative proteomics and targeted transcriptomics analyses in cardiac endothelial cells unravel mechanisms of long-term radiation-induced vascular dysfunction. J. Proteome Res. 14, 1203-1219 (2015)

Balasundaram, G.#, Ho, C.J.H.#, Li, K., Driessen, W.H.P. , Dinish, U.S., Wong, C.L., Ntziachristos, V. , Liu, B., Olivo, M.C.D.°: Molecular photoacoustic imaging of breast cancer using an actively targeted conjugated polymer. Int. J. Nanomed. 10, 387-397 (2015)

Bézière, N. °, Ntziachristos, V. : Optoacoustic imaging of naphthalocyanine: Potential for contrast enhancement and therapy monitoring. J. Nucl. Med. 56, 323-328 (2015)

de Boer, E., Harlaar, N.J., Taruttis, A., Nagengast, W.B., Rosenthal, E.L., Ntziachristos, V. , van Dam, G.M.°: Optical innovations in surgery. Br. J. Surg. 102, e56-e72 (2015)

Dean-Ben, X.L. #, Estrada, H. #, Razansky, D. °: Shaping volumetric light distribution through turbid media using real-time three-dimensional opto-acoustic feedback. Opt. Lett. 40, 443-446 (2015)

Diot, G. , Dima, A. , Ntziachristos, V. °: Multispectral opto-acoustic tomography of exercised muscle oxygenation. Opt. Lett. 40, 1496-1499 (2015)

Fehm, T. , Dean-Ben, X.L. , Razansky, D. °: Hybrid optoacoustic and ultrasound imaging in three dimensions and real time by optical excitation of a passive element. Proc. SPIE 9323:93232X (2015)

Gottschalk, S. , Fehm, T. , Dean-Ben, X.L. , Razansky, D. °: Noninvasive real-time visualization of multiple cerebral hemodynamic parameters in whole mouse brains using five-dimensional optoacoustic tomography. J. Cereb. Blood Flow Metab. 35, 531-535 (2015)

Kneipp, M. , Turner, J.E. , Estrada, H. , Rebling, J. , Shoham, S. , Razansky, D. °: Effects of the murine skull in optoacoustic brain microscopy. J. Biophotonics, DOI: 10.1002/jbio.201400152 (2015)

Knowlton, S.M., Sadasivam, M. , Tasoglu, S.°: Microfluidics for sperm research. Trends Biotechnol. 33, 221-229 (2015)

Kopanitsa, G.°, Veseli, H. , Yampolsky, V.: Development, implementation and evaluation of an information model for archetype based user responsive medical data visualization. J. Biomed. Inform., DOI: 10.1016/j.jbi.2015.04.009 (2015)


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Mandal, S. , Nasonova, E., Dean-Ben, X.L. , Razansky, D. °: Fast calibration of speed-of-sound using temperature prior in whole-body small animal optoacoustic imaging. Proc. SPIE 9323:93232Q (2015)

Midha, N., Mandal, S. : Making health care universally accessible : The emergence of telemedicine as a core necessity. IEEE Pulse 5, 4-7 (2014)

Mohajerani, P. , Tzoumas, S. , Rosenthal, A. , Ntziachristos, V. °: Optical and optoacoustic based tomography : Theory and current challenges for deep tissue imaging of optical contrast. IEEE Signal Process. Lett. 32, 88-100 (2015)

Multhoff, G. °, Pockley, A.G., Schmid, T.E., Schilling, D.: The role of Heat shock protein 70 (Hsp70) in radiation-induced immunomodulation. Cancer Lett., DOI: 10.1016/j.canlet.2015.02.013 (2015)

Nahrendorf, M.°, Frantz, S., Swirski, F.K., Mulder, W.J., Randolph, G.J., Ertl, G., Ntziachristos, V. , Piek, J.J., Stroes, E.S., Schwaiger, M., Mann, D.L., Fayad, Z.A.: Imaging systemic inflammatory networks in ischemic heart disease. J. Am. Coll. Cardiol. 65, 1583-1591 (2015)

Omar, M. , Schwarz, M. , Soliman, D. , Symvoulidis, P. , Ntziachristos, V. °: Pushing the optical Imaging limits of cancer with multi-frequency-band Raster-Scan Optoacoustic Mesoscopy (RSOM). Neoplasia 17, 208-214 (2015)

Pang, G.A. , Bay, E. , Dean-Ben, X.L. , Razansky, D. °: Optoacoustic monitoring of real-time lesion formation during radiofrequency catheter ablation. Proc. SPIE 9323:932308 (2015)

Radrich, K. , Ntziachristos, V. °: Quantitative multi-spectral oxygen saturation measurements independent of tissue optical properties. J. Biophotonics, DOI: 10.1002/jbio.201400092 (2015)

Schilling, D. , Kühnel, A., Konrad, S., Tetzlaff, F., Bayer, C., Yaglom, J., Multhoff, G. °: Sensitizing tumor cells to radiation by targeting the heat shock response. Cancer Lett. 360, 294-301 (2015)

Stiel, A.C., Dean-Ben, X.L. , Jiang, Y. , Ntziachristos, V. , Razansky, D. , Westmeyer, G.G. °: High-contrast imaging of reversibly switchable fluorescent proteins via temporally unmixed multispectral optoacoustic tomography. Opt. Lett. 40, 367-370 (2015)

Taruttis, A., Ntziachristos, V. °: Advances in real-time multispectral optoacoustic imaging and its applications. Nat. Photonics 9, 219-227 (2015)

Taruttis, A. , van Dam, G.M., Ntziachristos, V. °: Mesoscopic and macroscopic optoacoustic imaging of cancer. Cancer Res. 75, 1548-1559 (2015)

Voss, A.°, Schroeder, R., Heitmann, A., Peters, A. , Perz, S.: Short-term heart rate variability-influence of gender and age in healthy subjects. PLoS ONE 10:e0118308 (2015)


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Ziegler, D., Voss, A., Rathmann, W., Strom, A., Perz, S., Roden, M., Peters, A. , Meisinger, C. , KORA Study Group (Heinrich, J. , Gieger, C. , Grallert, H. , Holle, R. , Leidl, R. , Strauch, K. ): Increased prevalence of cardiac autonomic dysfunction at different degrees of glucose intolerance in the general population: The KORA S4 survey. Diabetologia 58, 1118-1128 (2015)


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de Bin, R.°, Herold, T. , Boulesteix, A.-L.: Added predictive value of omics data: specific issues related to validation illustrated by two case studies. BMC Med. Res. Methodol. 14:117 (2014)

God, J.M., Cameron, C., Figueroa, J., Amria, S., Hossain, A., Kempkes, B. , Bornkamm, G.W. , Stuart, R.K., Blum, J.S., Haque, A.°: Elevation of c-MYC disrupts HLA class II-mediated immune recognition of human B cell tumors. J. Immunol. 194, 1434-1445 (2015)

Guenova, E.#°, Skabytska, Y.#, Hoetzenecker, W.#, Weindl, G., Sauer, K., Tham, M., Kim, K.W., Park, J.H., Seo, J.H., Ignatova, D., Cozzio, A., Levesque, M.P., Volz, T., Köberle, M., Kaesler, S., Thomas, P., Mailhammer, R. , Ghoreschi, K., Schäkel, K., Amarov, B., Eichner, M., Schaller, M., Clark, R.A., Röcken, M.°, Biedermann, T.°: IL-4 abrogates TH17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells. Proc. Natl. Acad. Sci. U.S.A. 112, 2163-2168 (2015)

Kellner, M. , Rohrmoser, M. , Forne, I., Voss, K. , Burger, K. , Mühl, B. , Gruber-Eber, A. , Kremmer, E. , Imhof, A., Eick, D. °: DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex. Exp. Cell Res., DOI: 10.1016/j.yexcr.2015.03.017 (2015)

Matsushita, M., Freigang, S., Schneider, C., Conrad, M. , Bornkamm, G.W. , Kopf, M.°: T cell lipid peroxidation induces ferroptosis and prevents immunity to infection. J. Exp. Med. 212, 555-568 (2015)

Neumann, M., Vosberg, S. , Schlee, C., Heesch, S., Schwartz, S., Gökbuget, N., Hoelzer, D., Graf, A., Krebs, S., Bartram, I., Blum, H., Brüggemann, M., Hecht, J., Bohlander, S.K. , Greif, P.A. , Baldus, C.D.°: Mutational spectrum of adult T-ALL. Oncotarget 6, 2754-2766 (2014)

Vick, B. , Rothenberg, M., Sandhöfer, N. , Carlet, M. , Finkenzeller, C. , Krupka, C. , Grunert, M. , Trumpp, A., Corbacioglu, S., Ebinger, M., Andre, M.C., Hiddemann, W. , Schneider, S., Subklewe, M. , Metzeler, K.H., Spiekermann, K. , Jeremias, I. °: An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging. PLoS ONE 10:e0120925 (2015)

Zacarias-Cabeza, J.#, Belhocine, M.#, Vanhille, L., Cauchy, P., Koch, F., Pekowska, A., Fenouil, R., Bergon, A., Gut, M., Gut, I., Eick, D. , Imbert, J., Ferrier, P.°, Andrau, J.C.°, Spicuglia, S.°: Transcription-dependent generation of a specialized chromatin structure at the TCRβ locus. J. Immunol. 194, 3432-3443 (2015)


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Barnsley, M.F.°, Massopust, P. °: Bilinear fractal interpolation and box dimension. J. Approx. Theory 192, 362-378 (2015)


Buettner, F. #, Natarajan, K.N.#, Casale, F.P., Proserpio, V., Scialdone, A., Theis, F.J. , Teichmann, S.A., Marioni, J.C.°, Stegle, O.°: Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells. Nat. Biotechnol. 33, 155-160 (2015)

Calzolari, F. , Michel, J. , Baumgart, E.V. , Theis, F.J. , Götz, M.°, Ninkovic, J. °: Fast clonal expansion and limited neural stem cell self-renewal in the adult subependymal zone. Nat. Neurosci. 18, 490-492 (2015)

Demaret, L. °, Iske, A.°: Optimal N-term approximation by linear splines over anisotropic Delaunay triangulations. Math. Comput. 84, 1241-1264 (2015)

Frikel, J. , Quinto, E.T.: Artifacts in incomplete data tomography with applications to photoacoustic tomography and sonar. SIAM J. Appl. Math. 75, 703-725 (2015)

Griese, M.#°, Kirmeier, H.G.#, Liebisch, G. , Rauch, D., Stückler, F. , Schmitz, G., Zarbock, R.: Surfactant lipidomics in healthy children and childhood interstitial lung disease. PLoS ONE 10:e0117985 (2015)

Helmbrecht, M.S. #, Soellner, H. #, Castiblanco-Urbina, M.A. , Winzeck, S. , Sundermeier, J. , Theis, F.J. , Fouad, K., Huber, A.B. °: A critical period for postnatal adaptive plasticity in a model of motor axon miswiring. PLoS ONE 10:e0123643 (2015)

Hense, B.A. °, Schuster, M.°: Core principles of bacterial autoinducer systems. Microbiol. Mol. Biol. Rev. 79, 153-169 (2015)

Hug, S.°, Schwarzfischer, M. , Hasenauer, J. , Marr, C. , Theis, F.J. °: An adaptive scheduling scheme for calculating Bayes factors with thermodynamic integration using Simpson’s rule. Stat. Comp., DOI: 10.1007/s11222-015-9550-0 (2015)

Illner, K. , Miettinen, J., Fuchs, C. , Taskinen, S., Nordhausen, K., Oja, H., Theis, F.J. °: Model selection using limiting distributions of second-order blind source separation algorithms. Signal Process. 113, 95-103 (2015)

Kondofersky, I. , Fuchs, C. , Theis, F.J. °: Identifying latent dynamic components in biological systems. IET Syst. Biol., DOI: 10.1049/iet-syb.2014.0013 (2015)


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Kong, B., Bruns, P. , Raulefs, S., Rieder, S., Paul, L., da Costa, O.P., Buch, T., Theis, F.J. , Michalski, C.W., Kleeff, J.: Metabolism gene signatures and surgical site infections in abdominal surgery. Int. J. Surg. 14, 67-74 (2015)

Mai, S.T.°, He, X., Feng, J., Plant, C. , Böhm, C.: Anytime density-based clustering of complex data. Knowl. Inf. Syst., DOI: 10.1007/s10115-014-0797-0 (2015)

Moignard, V., Woodhouse, S., Haghverdi, L. , Lilly, A.J., Tanaka, Y., Wilkinson, A.C., Buettner, F. , Macaulay, I.C., Jawaid, W., Diamanti, E., Nishikawa, S.I., Piterman, N., Kouskoff, V., Theis, F.J. , Fisher, J.°, Gottgens, B.°: Decoding the regulatory network of early blood development from single-cell gene expression measurements. Nat. Biotechnol. 33, 269-276 (2015)

Morath, V., Truong, D.J.J., Albrecht, F., Polte, I., Ciccone, R.A., Funke, L.F., Reichart, L., Wolf, C.G., Brunner, A.D., Fischer, K., Schneider, P.C., Brüggenthies, J.B., Fröhlich, F. , Wiedemann, G., Reski, R., Skerra, A.°: Design and characterization of a modular membrane protein anchor to functionalize the moss Physcomitrella patens with extracellular catalytic and/or binding activities. ACS Synth. Biol. 3, 990-994 (2014)

Müller, J. °, Jiang, H.: Graphical limit sets for general cellular automata. Theor. Comput. Sci. 580, 14-27 (2015)

Müller, S., Raulefs, S., Bruns, P., Afonso-Grunz, F., Plötner, A., Thermann, R., Jager, C., Schlitter, A.M., Kong, B., Regel, I., Roth, W.K., Rotter, B., Hoffmeier, K., Kahl, G.F., Koch, I., Theis, F.J. , Kleeff, J., Winter, P., Michalski, C.W.°: Next-generation sequencing reveals novel differentially regulated mRNAs, lncRNAs, miRNAs, sdRNAs and a piRNA in pancreatic cancer. Mol. Cancer 14:94 (2015)

Obermaier, J. , Stavropoulou, F. : Generalized polynomial chaos expansions with weights. J. Comput. Anal. Appl. 18, 30-45 (2015)

Pérez-Velázquez, J. °, Quinones, P.A.°, Hense, B.A. °, Kuttler, C.°: A mathematical model to investigate quorum sensing regulation and its heterogeneity in Pseudomonas syringae on leaves. Ecol. Complex. 21, 128-141 (2015)

Popovic, N.°, Marr, C. , Swain, P.S.: A geometric analysis of fast-slow models for stochastic gene expression. J. Math. Biol., DOI: 10.1007/s00285-015-0876-1 (2015)


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Schmidt, J. , Panzilius, E. , Bartsch, H.S., Irmler, M. , Beckers, J. , Kari, V., Linnemann, J. , Dragoi, D. , Hirschi, B. , Kloos, U. , Sass, S. , Theis, F.J. , Kahlert, S., Johnsen, S.A., Sotlar, K., Scheel, C. °: Stem-cell-like properties and epithelial plasticity arise as stable traits after transient Twist1 activation. Cell Rep. 10, 131-139 (2015)

Theis, F.J. °, Ugelvig, L.V.°, Marr, C.°, Cremer, S.°: Opposing effects of allogrooming on disease transmission in ant societies. Philos. Trans. R. Soc. B - Biol. Sci. 370, DOI: 10.1098/rstb.2014.0108 (2015)


Weinmann, A. °, Storath, M.: Iterative Potts and Blake-Zisserman minimization for the recovery of functions with discontinuities from indirect measurements. Proc. R. Soc. London A 471:20140638 (2015)

Weinmann, A. °, Storath, M. °, Demaret, L. °: The L1-Potts functional for robust jump-sparse reconstruction. SIAM J. Numer. Anal. 53, 644-673 (2015)

Wieczorek, M.°, Frikel, J. , Vogel, J., Eggl, E., Kopp, F., Noel, P.B., Pfeiffer, F., Demaret, L. , Lasser, T.: X-ray computed tomography using curvelet sparse regularization. Med. Phys. 42, 1555-1565 (2015)

Yang, Q., Boehm, C., Scholz, M., Plant, C. , Shao, J.°: Predicting multiple functions of sustainable flood retention basins under uncertainty via multi-instance multi-label learning. Water 7, 1359-1377 (2015)


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Andjeli, S.#, Lumi, X.#, Yan, X., Graw, J. , Moe, M.C., Facskó, A., Hawlina, M., Petrovski, G.°: Characterization of ex vivo cultured neuronal- and glial- like cells from human idiopathic epiretinal membranes. BMC Ophthalmol. 14:165 (2014)

Andjelić, S., Drašlar, K., Lumi, X., Yan, X., Graw, J. , Facskó, A., Hawlina, M., Petrovski, G.°: Morphological and proliferative studies on ex vivo cultured human anterior lens epithelial cells - relevance to capsular opacification. Acta Ophthalmol., DOI: 10.1111/aos.12655 (2015)

Becker, L. #, Kling, E. #, Schiller, E. , Zeh, R., Schrewe, A. , Hölter, S.M. , Mossbrugger, I. , Calzada-Wack, J., Strecker, V., Wittig, I., Dumitru, I., Wenz, T., Bender, A., Aichler, M. , Janik, D. , Neff, F. , Walch, A.K. , Quintanilla-Fend, L., Floss, T. , Bekeredjian, R. , Gailus-Durner, V. , Fuchs, H. , Wurst, W. , Meitinger, T. , Prokisch, H. , Hrabě de Angelis, M. , Klopstock, T. °: MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy. PLoS ONE 9:e114918 (2014)

Brandl, C. , Ortiz, O. , Röttig, B. , Wefers, B. , Wurst, W. °, Kühn, R. °: Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos. FEBS Open Bio 5, 26-35 (2015)

Chu, V.T., Weber, T., Wefers, B. , Wurst, W. , Sander, S., Rajewsky, K.°, Kühn, R. °: Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells. Nat. Biotechnol., DOI: 10.1038/nbt.3198 (2015)

Hellfritsch, J., Kirsch, J., Schneider, M., Perisic, T. , Wortmann, M., Frijhoff, J., Dagnell, M., Fey, T., Esposito, I. , Kölle, P., Pogoda, K., Ingold, I., Angeli, J.P., Kuhlencordt, P., Östman, A., Pohl, U., Beck, H.°, Conrad, M. °: Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis. Antioxid. Redox Signal. 22, 938-950 (2015)

Helmbrecht, M.S. #, Soellner, H. #, Castiblanco-Urbina, M.A. , Winzeck, S. , Sundermeier, J. , Theis, F.J. , Fouad, K., Huber, A.B. °: A critical period for postnatal adaptive plasticity in a model of motor axon miswiring. PLoS ONE 10:e0123643 (2015)

Helmbrecht, M.S. °, Söllner, H. , Truckenbrodt, A.M. , Sundermeier, J. , Cohrs, C. , Hans, W. , Hrabě de Angelis, M. , Feuchtinger, A. , Aichler, M. , Fouad, K., Huber, A.B. °: Loss of Npn1 from motor neurons causes postnatal deficits independent from Sema3A signaling. Dev. Biol. 399, 2-14 (2015) [published online 2014]

Hüttl, R.E. #, Luxenhofer, G. #, Bianchi, E. #, Haupt, C. , Joshi, R., Prochiantz, A., Huber, A.B. °: Engrailed 1 mediates correct formation of limb innervation through two distinct mechanisms. PLoS ONE 10:e0118505 (2015)

Ingold, I. , Aichler, M. , Yefremova, E. , Roveri, A., Buday, K. , Doll, S. , Tasdemir, A. , Hoffard, N. , Wurst, W., Walch, A.K. , Ursini, F., Friedmann Angeli, J.P. , Conrad, M. °: Expression of a catalytically inactive mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility. J. Biol. Chem., DOI: 10.1074/jbc.M115.656363 (2015)


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Kagan, V.E.°, Tyurina, Y.Y., Tyurin, V.A., Mohammadyani, D., Friedmann Angeli, J.P. , Baranov, S.V., Klein-Seetharaman, J., Friedlander, R.M., Mallampalli, R.K., Conrad, M. , Bayir, H.: Cardiolipin signaling mechanisms: Collapse of asymmetry and oxidation. Antioxid. Redox Signal., DOI: 10.1089/ars.2014.6219 (2015)

Kessler, T.#, Zhang, L.#, Liu, Z., Yin, X., Huang, Y., Wang, Y., Fu, Y., Mayr, M., Ge, Q., Xu, Q., Zhu, Y., Wang, X., Schmidt, K.J., de Wit, C., Erdmann, J., Schunkert, H., Aherrahrou, Z.#°, Kong, W.#°, German Mouse Clinic Consortium (Adamski, J. , Adler, T. , Aguilar-Pimentel, J.A. , Amarie, O.V. , Becker, L. , Beckers, J. , Brachthäuser, L. , Busch, D.H. , Calzada-Wack, J. , Eickelberg. O. , Fuchs, H. , Gailus-Durner, V. , Garrett, L. , Gegenfurtner, M , Graw, J. , Hans, W. , Hölter, S.M. , Horsch, M. , Hrabě de Angelis, M. , Janik, D. , Klein-Rodewald, T. , Klingenspor, M. , Klopstock, T. , Lengger, C. , Leuchtenberger, S. , Maier, H. , Moreth, K. , Neff, F. , Ollert, M. , Prehn, C. , Puk, O. , Rathkolb, B. , Rozman, J., Steinkamp, R. , Stöger, C. , Stöger, T. , Vernaleken, A.M. , Yildirim, A.Ö. , Wurst, W. , Zimprich, A. ): ADAMTS-7 inhibits re-endothelialization of injured arteries and promotes vascular remodleing via cleavage of thrombospondin-1 Circulation 131, 1191-1201 (2015)

Kobayashi, S. , Sato, M., Kasakoshi, T., Tsutsui, T., Sugimoto, M., Osaki, M., Okada, F., Igarashi, K., Hiratake, J., Homma, T., Conrad, M. , Fujii, J., Soga, T., Bannai, S., Sato, H.°: Cystathionine is a novel substrate of cystine/glutamate transporter: Implications for immune function. J. Biol. Chem. 290, 8778-8788 (2015)

Kunze, S. , Dalke, C. , Fuchs, H. , Klaften, M. , Rössler, U., Hornhardt, S., Gomolka, M., Puk, O. , Sabrautzki, S., Kulka, U., Hrabě de Angelis, M. , Graw, J. °: New mutation in the mouse Xpd/Ercc2 gene leads to recessive cataracts. PLoS ONE 10:e0125304 (2015)

Labazi, M., McNeil, A.K., Kurtz, T., Lee, T.C., Pegg, R.B., Friedmann Angeli, J.P. , Conrad, M. , McNeil, P.L.°: The antioxidant requirement for plasma membrane repair in skeletal muscle. Free Radic. Biol. Med. 84, 246-253 (2015)

Matsui, H.°, Namikawa, K. , Köster, R.W.: Identification of the zebrafish red nucleus using wheat germ agglutinin transneuronal tracing. Commun. Integr. Biol. 7:e994383 (2014)

Matsushita, M., Freigang, S., Schneider, C., Conrad, M. , Bornkamm, G.W. , Kopf, M.°: T cell lipid peroxidation induces ferroptosis and prevents immunity to infection. J. Exp. Med. 212, 555-568 (2015)

Mellett, M., Atzei, P., Bergin, R., Horgan, A., Floss, T. , Wurst, W. , Callanan, J.J., Moynagh, P.N.°: Orphan receptor IL-17RD regulates toll-like receptor signalling via SEFIR/TIR interactions. Nat. Commun. 6:6669 (2015)

Riemer, J.°, Schwarzländer, M., Conrad, M. , Herrmann, J.M.: Thiol switches in mitochondria: Operation and physiological relevance. Biol. Chem. 396, 465-482 (2015)

Song, H., Lee, B., Pyun, D., Guimera, J. , Son, Y., Yoon, J., Baek, K., Wurst, W. , Jeong, Y.°: Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev. Biol. 398, 280-291 (2015)


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Stiel, A.C., Dean-Ben, X.L. , Jiang, Y. , Ntziachristos, V. , Razansky, D. , Westmeyer, G.G. °: High-contrast imaging of reversibly switchable fluorescent proteins via temporally unmixed multispectral optoacoustic tomography. Opt. Lett. 40, 367-370 (2015)

Tischner, C.#, Hofer, A.#, Wulff, V., Stepek, J., Dumitru, I., Becker, L. , Haack, T.B. , Kremer, L. , Datta, A.N., Sperl, W., Floss, T. , Wurst, W. , Chrzanowska-Lightowlers, Z.M., Hrabě de Angelis, M. , Klopstock, T. , Prokisch, H. , Wenz, T.°: MTO1 mediates tissue-specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention. Hum. Mol. Genet. 24, 2247-2266 (2015)

Vogl, A.M.#, Brockmann, M.M.#, Giusti, S.A., Maccarrone, G., Vercelli, C.A., Bauder, C.A., Richter, J.S., Roselli, F., Hafner, A.S., Dedic, N. , Wotjak, C.T., Vogt Weisenhorn, D.M. , Choquet, D., Turck, C.W., Stein, V., Deussing, J.M., Refojo, D.°: Neddylation inhibition impairs spine development, destabilizes synapses and deteriorates cognition. Nat. Neurosci. 18, 239-251 (2015)

Washkowitz, A.J., Schall, C., Zhang, K.L., Wurst, W. , Floss, T. , Mager, J., Papaioannou, V.E.°: Mga is essential for the survival of pluripotent cells during peri-implantation development. Development 142, 31-40 (2015)


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Clemmensen, C. , Müller, T.D. , Finan, B. , Tschöp, M.H. °, DiMarchi, R.: Current and emerging treatment options in diabetes care. Handb. Exp. Pharmacol., DOI: 10.1007/164_2015_7 (2015)


Dinter, J.#, Mühlhaus, J.#, Wienchol, C.L., Yi, C.-X., Nürnberg, D., Morin, S. , Grüters, A., Köhrle, J., Schöneberg, T., Tschöp, M.H., Krude, H., Kleinau, G., Biebermann, H.°: Inverse agonistic action of 3-iodothyronamine at the human trace amine-associated receptor 5. PLoS ONE 10:e0117774 (2015)

Eugster, A.°, Lindner, A., Catani, M., Heninger, A.K., Dahl, A., Klemroth, S., Kühn, D., Dietz, S., Bickle, M., Ziegler, A.-G. , Bonifacio, E. : High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells. J. Immunol. 194, 2531-2538 (2015)

Fuchs, Y.F., Jainta, G.W., Kühn, D., Wilhelm, C., Weigelt, M., Karasinsky, A., Upadhyaya, B., Ziegler, A.-G. , Bonifacio, E. °: Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires purified CD8+ T cells and MHC class I expressing antigen presenting cell lines. Clin. Immunol. 157, 216-225 (2015)

Jastroch, M. °, Andersson, L.B.: When pigs fly, UCP1 makes heat. Mol. Metab. 4, 359-362 (2015)

Kälin, S. , Heppner, F.L., Bechmann, I., Prinz, M., Tschöp, M.H. °, Yi, C.X.: Hypothalamic innate immune reaction in obesity. Nat. Rev. Endocrinol., DOI: 10.1038/nrendo.2015.48 (2015)

Müller, T.D. , Nogueiras, R.A., Andermann, M.L., Andrews, Z.B., Anker, S.D., Argente, J., Batterham, R., Benoit, S.C., Bowers, C.Y., Broglio, F., Casanueva, F.F.F., D'Alessio, D., Depoortere, I., Geliebter, A.A., Ghigo, E., Cole, P.A., Cowley, M.A., Cummings, D.E., Dagher, A., Diano, S., Dickson, S.L., Dieguez, C., Granata, R., Grill, H.J., Grove, K.L., Habegger, K.M., Heppner, K.M., Heiman, M.L., Holsen, L., Holst, B., Inui, A., Jansson, J.O., Kirchner, H., Korbonits, M., Laferrère, B., LeRoux, C.W., López, M.D., Morin, S. , Nakazato, M., Nass, R., Perez-Tilve, D., Pfluger, P.T. , Schwartz, T.W., Seeley, R.J., Sleeman, M.W., Sun, Y., Sussel, L., Tong, J., Thorner, M.O., van der Lely, A.J., van der Ploeg, L.H.T., Zigman, J.M., Kojima, M., Kangawa, K., Smith, R.G., Horvath, T., Tschöp, M.H. °: Ghrelin. Mol. Metab., DOI: 10.1016/j.molmet.2015.03.005 (2015)

Reis, W.L. , Yi, C.-X., Gao, Y., Tschöp, M.H. , Stern, J.E.°: Brain innate immunity regulates hypothalamic arcuate neuronal activity and feeding behavior. Endocrinology 156, 1303-1315 (2015)



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Roscioni, S. , Heerspink, H.J.°: New nonabsorbable potassium-exchange resins in hyperkalaemia. Nat. Rev. Nephrol. 11, 205-206 (2015)


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Bongers, M.N.°, Stefan, N. , Fritsche, A. , Häring, H.-U. , Nikolaou, K., Schick, F., Machann, J. : Lebervolumen, Leberfettanteil und Körpergewicht im Verlauf einer Lebensstilinterventionsstudie : Eine Analyse mit quantitativen MR-basierten Methoden. Radiologe 55, 323-328 (2015)

Dai, W., Yin, P., Zeng, Z., Kong, H., Tong, H., Xu, Z.L., Lu, X., Lehmann, R. °, Xu, G.W.°: Nontargeted modification-specific metabolomics study based on liquid chromatography high-resolution mass spectrometry. Anal. Chem. 86, 9146-9153 (2014)

Dimitrov, S.°, Besedovsky, L., Born, J. , Lange, T.: Differential acute effects of sleep on spontaneous and stimulated production of tumor necrosis factor in men. Brain Behav. Immun., DOI: 10.1016/j.bbi.2014.11.017 (2015)

Eckel, N., Mühlenbruch, K., Meidtner, K., Boeing, H., Stefan, N. , Schulze, M.B.°: Characterization of metabolically unhealthy normal-weight individuals: Risk factors and their associations with type 2 diabetes. Metab.-Clin. Exp., DOI: 10.1016/j.metabol.2015.03.009 (2015)

Gancheva, S., Koliaki, C., Bierwagen, A., Nowotny, P., Heni, M. , Fritsche, A. , Häring, H.-U. , Szendrödi, J., Roden, M.°: Effects of intranasal insulin on hepatic fat accumulation and energy metabolism in humans. Diabetes, DOI: 10.2337/db14-0892 (2015)

Kröger, J.°, Jacobs, S., Jansen, E.H.J.M., Fritsche, A. , Boeing, H., Schulze, M.B.: Erythrocyte membrane fatty acid fluidity and risk of type 2 diabetes in the EPIC-Potsdam study. Diabetologia 58, 282-289 (2015)

Kullmann, S. °, Schweizer, F., Veit, R., Fritsche, A. , Preissl, H. : Compromised white matter integrity in obesity. Obes. Rev. 16, 273-281 (2015)

Kullmann, S. °, Heni, M. , Fritsche, A. , Preissl, H. : Insulin action in the human brain: Evidence from neuroimaging studies. J. Neuroendocrinol., DOI: 10.1111/jne.12254 (2015)

Kullmann, S. °, Heni, M. , Veit, R. , Scheffler, K., Machann, J. , Häring, H.-U. , Fritsche, A. , Preissl, H. : Selective insulin resistance in homeostatic and cognitive control brain areas in overweight and obese adults. Diabetes Care, DOI: 10.2337/dc14-2319 (2015)

Nettersheim, A., Hallschmid, M. , Born, J. , Diekelmann, S.°: The role of sleep in motor sequence consolidation: Stabilization rather than enhancement. J. Neurosci. 35, 6696-6702 (2015)

Nowotny, B., Zahiragic, L., Bierwagen, A., Kabisch, S., Groener, J.B., Nowotny, P.J., Fleitmann, A.K., Herder, C., Pacini, G., Erlund, I., Landberg, R., Häring, H.-U. , Pfeiffer, A.F., Nawroth, P.P., Roden, M.°: Low-energy diets differing in fibre, red meat and coffee intake equally improve insulin sensitivity in type 2 diabetes: A randomised feasibility trial. Diabetologia 58, 255-264 (2015)


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Panse, M., Gerst, F. , Kaiser, G. , Teutsch, C.A., Dölker, R., Wagner, R. , Häring, H.-U. , Ullrich, S. °: Activation of Extracellular signal-Regulated protein Kinases 1 and 2 (ERK1/2) by Free Fatty Acid Receptor 1 (FFAR1/GPR40) protects from palmitate-induced beta cell death, but plays no role in insulin secretion. Cell. Physiol. Biochem. 35, 1537-1545 (2015)

Rimmele, U.°, Besedovsky, L., Lange, T., Born, J. : Emotional memory can be persistently weakened by suppressing cortisol during retrieval. Neurobiol. Learn. Mem. 119, 102-107 (2015)

Sartorius, T. °, Drescher, A., Panse, M., Lastovicka, P., Peter, A., Weigert, C. , Kostenis, E., Ullrich, S., Häring, H.-U. : Mice lacking Free Fatty Acid Receptor 1 (GPR40/FFAR1) are protected against conjugated linoleic acid-induced fatty liver but develop inflammation and insulin resistance in the brain. Cell. Physiol. Biochem. 35, 2272-2284 (2015)


Schmidt, E.#, Linz, B.#, Diekelmann, S., Besedovsky, L., Lange, T., Born, J. °: Effects of an interleukin-1 receptor antagonist on human sleep, sleep-associated memory consolidation, and blood monocytes. Brain Behav. Immun., DOI: 10.1016/j.bbi.2014.11.012 (2015)


Wolf, M., Riedlinger, I., Lehmann, R. , Häring, H.-U. , Schleicher, E. , Peter, A. °: Comparison of the automated KRYPTOR chromogranin A assay with the DAKO ELISA. Clin. Lab. 60, 2103-2106 (2014)


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Agardh, D.°, Lee, H.S., Kurppa, K., Simell, V., Aronsson, C.A., Jörneus, O., Hummel, M. , Liu, E., Koletzko, S., TEDDY Study Group (Ziegler, A.-G. , Beyerlein, A. , Bonifacio, E. , Hummel, S. , Foterek, K. , Kersting, M., Knopff, A. , Peplow, C. , Roth, R. , Stock, J. , Strauss, E. , Warncke, K. , Winkler, C. ): Clinical features of celiac disease: A prospective birth cohort. Pediatrics 135, 627-634 (2015)

Aronsson, C.A.°, Lee, H.S., Liu, E., Uusitalo, U., Hummel, S. , Yang, J., Hummel, M. , Rewers, M., She, J.X., Simell, O., Toppari, J., Ziegler, A.-G. , Krischer, J., Virtanen, S.M., Norris, J.M., Agardh, D., TEDDY Study Group: Age at gluten introduction and risk of celiac disease. Pediatrics 135, 239 -245 (2015)

Beyerlein, A. , Krasmann, M. , Thiering, E. , Kusian, D. , Markevych, I. , D'Orlando, O. , Warncke, K., Jochner, S., Heinrich, J. , Ziegler, A.-G. °: Ambient air pollution and early manifestation of type 1 diabetes. Epidemiology 26, e31-e32 (2015)


Dopico, X.C., Evangelou, M., Ferreira, R.C., Guo, H., Pekalski, M.L., Smyth, D.J., Cooper, N., Burren, O.S., Fulford, A.J., Hennig, B.J., Prentice, A.M., Ziegler, A.-G. , Bonifacio, E., Wallace, C., Todd, J.A.°: Widespread seasonal gene expression reveals annual differences in human immunity and physiology. Nat. Commun. 6:7000 (2015)

Eugster, A.°, Lindner, A., Catani, M., Heninger, A.K., Dahl, A., Klemroth, S., Kühn, D., Dietz, S., Bickle, M., Ziegler, A.-G. , Bonifacio, E. : High diversity in the TCR repertoire of GAD65 autoantigen-specific human CD4+ T cells. J. Immunol. 194, 2531-2538 (2015)

Fuchs, Y.F., Jainta, G.W., Kühn, D., Wilhelm, C., Weigelt, M., Karasinsky, A., Upadhyaya, B., Ziegler, A.-G. , Bonifacio, E. °: Vagaries of the ELISpot assay: Specific detection of antigen responsive cells requires purified CD8+ T cells and MHC class I expressing antigen presenting cell lines. Clin. Immunol. 157, 216-225 (2015)

Krischer, J.P.°, Lynch, K.F., Schatz, D.A., Ilonen, J., Lernmark, A., Hagopian, W.A., Rewers, M.J., She, J.X., Simell, O.G., Toppari, J., Ziegler, A.-G. , Akolkar, B., Bonifacio, E., TEDDY Study Group (Beyerlein, A. , Hummel, M. , Hummel, S. , Foterek, K. , Kersting, M. , Knopff, A. , Koletzko, S. , Peplow, C. , Roth, R. , Stock, J. , Strauss, E. , Warncke, K. , Winkler, C. ): The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: The TEDDY study. Diabetologia 58, 980-987 (2015)

Lönnrot, M.°, Lynch, K., Larsson, H.E., Lernmark, A., Rewers, M., Hagopian, W., She, J., Simell, O., Ziegler, A.-G., Akolkar, B., Krischer, J., Hyoty, H., TEDDY Study Group: A method for reporting and classifying acute infectious diseases in a prospective study of young children: TEDDY. BMC Pediatr. 15:24 (2015)


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Raz, I.°, Ziegler, A.-G. , Linn, T., Schernthaner, G., Bonnici, F., Distiller, L.A., Giordano, C., Giorgino, F., de Vries, L., Mauricio, D., Procházka, V., Wainstein, J., Elias, D., Avron, A., Tamir, M., Eren, R., Peled, D., Dagan, S., Cohen, I.R., Pozzilli, P.: Treatment of recent-onset type 1 diabetic patients with DiaPep277: Results of a double-blind, placebo-controlled, randomized phase 3 trial. Diabetes Care 37, 1392-1400 (2014)


Warncke, K. °, Liptay, S., Fröhlich-Reiterer, E., Scheuing, N., Schebek, M., Wolf, J., Rohrer, T.R., Meissner, T., Holl, R.W.: Vascular risk factors in children, adolescents, and young adults with type 1 diabetes complicated by celiac disease: Results from the DPV initiative. Pediatr. Diabetes, DOI: 10.1111/pedi.12261 (2015)


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Amaral, A.F.°, Minelli, C., Guerra, S., Wjst, M. , Probst-Hensch, N., Pin, I., Svanes, C., Janson, C., Heinrich, J., Jarvis, D.L.: The locus C11orf30 increases susceptibility to poly-sensitization. Allergy 70, 328–333 (2015) [published online 2014]

Asl, H.F., Talukdar, H.A., Kindt, A.S.D., Jain, R.K., Ermel, R., Ruusalepp, A., Nguyen, K.H., Dobrin, R., Reilly, D.F., Schunkert, H., Samani, N.J., Braenne, I., Erdmann, J., Melander, O., Qi, J., Ivert, T., Skogsberg, J., Schadt, E.E., Michoel, T., Bjorkegren, J.L.M.°, CARDIoGRAM Consortium (Döring, A. , Meisinger, C. , Meitinger, T. , Peters, A. , Wichmann, H.-E. ): Expression quantitative trait loci acting across multiple tissues are enriched in inherited risk for coronary artery disease. Circ. Cardiovasc. Genet. 8, 305-315 (2015)

Beelen, R.°, Hoek, G., Raaschou-Nielsen, O., Stafoggia, M., Andersen, Z.J., Weinmayr, G., Hoffmann, B., Wolf, K. , Samoli, E., Fischer, P.H., Nieuwenhuijsen, M.J., Xun, W.W., Katsouyanni, K., Dimakopoulou, K., Marcon, A., Vartiainen, E., Lanki, T., Yli-Tuomi, T., Oftedal, B., Schwarze, P.E., Nafstad, P., de Faire, U., Pedersen, N.L., Ostenson, C.G., Fratiglioni, L., Penell, J., Korek, M., Pershagen, G., Eriksen, K.T., Overvad, K., Sørensen, M., Eeftens, M., Peeters, P.H., Meliefste, K., Wang, M., Bueno-de-Mesquita, H.B., Sugiri, D., Krämer, U., Heinrich, J. , de Hoogh, K., Key, T., Peters, A. , Hampel, R. , Concin, H., Nagel, G., Jaensch, A., Ineichen, A., Tsai, M.Y., Schaffner, E., Probst-Hensch, N.M., Schindler, C., Ragettli, M.S., Vilier, A., Clavel-Chapelon, F., Declercq, C., Ricceri, F., Sacerdote, C., Galassi, C., Migliore, E., Ranzi, A., Cesaroni, G., Badaloni, C., Forastiere, F., Katsoulis, M., Trichopoulou, A., Keuken, M., Jedynska, A., Kooter, I.M., Kukkonen, J.V.K., Sokhi, R.S., Vineis, P., Brunekreef, B.: Natural cause mortality and long-term exposure to particle components: An analysis of 19 European cohorts within the multi-center ESCAPE project. Environ. Health Perspect., DOI: 10.1289/ehp.1408095 (2015)

Beyerlein, A. , Krasmann, M. , Thiering, E. , Kusian, D. , Markevych, I. , D'Orlando, O. , Warncke, K., Jochner, S., Heinrich, J. , Ziegler, A.-G. °: Ambient air pollution and early manifestation of type 1 diabetes. Epidemiology 26, e31-e32 (2015)

Bigert, C., Gustavsson, P., Straif, K., Pesch, B., Brüning, T., Kendzia, B., Schüz, J., Stücker, I., Guida, F., Brüske, I. , Wichmann, H.-E. , Pesatori, A.C., Landi, M.T., Caporaso, N., Tse, L.A., Yu, I.T., Siemiatycki, J., Pintos, J., Merletti, F., Mirabelli, D., Simonato, L., Jockel, K.H., Ahrens, W., Pohlabeln, H., Tardón, A., Zaridze, D., Field, J., 't Mannetje, A., Pearce, N., McLaughlin, J., Demers, P., Szeszenia-Dabrowska, N., Lissowska, J., Rudnai, P., Fabianova, E., Stanescu Dumitru, R., Bencko, V., Foretova, L., Janout, V., Boffetta, P., Forastiere, F., Bueno-de-Mesquita, B., Peters, S., Vermeulen, R., Kromhout, H., Olsson, A.C.°: Lung cancer risk among cooks when accounting for tobacco smoking: S pooled analysis of case-control studies from europe, Canada, new zealand, and china. J. Occup. Environ. Med. 57, 202-209 (2015)


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Casas, L.°, Sunyer, J., Tischer, C.G. , Gehring, U., Wickman, M., García-Esteban, R., Lehmann, I., Kull, I., Reich, A., Lau, S., Wijga, A.H., Antò, J.M., Nawrot, T.S., Heinrich, J. , Keil, T.O., Torrent, M.: Early-life house dust mite allergens, childhood mite sensitization, and respiratory outcomes. Allergy, DOI: 10.1111/all.12626 (2015)

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Deckert, A.°, Winkler, V.°, Meisinger, C. °, Heier, M.°, Becher, H.°: Suicide and external mortality pattern in a cohort of migrants from the former Soviet Union to Germany. J. Psychiatr. Res. 63, 36-42 (2015)

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Pirovano, A.°, Brandmaier, S. , Huijbregts, M.A., Ragas, A.M., Veltman, K., Hendriks, A.J.: The utilisation of structural descriptors to predict metabolic constants of xenobiotics in mammals. Environ. Toxicol. Pharmacol. 39, 247-258 (2015)

Quinones, P.A. °, Kirchberger, I. °, Amann, U. °, Heier, M.°, Kuch, B.°, von Scheidt, W.°, Meisinger, C. °: Does marital status contribute to the explanation of the hypercholesterolemia paradox in relation to long term mortality in myocardial infarction? Findings from the MONICA/KORA Myocardial Infarction Registry. Prev. Med. 75, 25-31 (2015)

Rahmioglu, N., MacGregor, S., Drong, A.W., Hedman, A.K., Harris, H.R., Randall, J.C., Prokopenko, I., International Endogene Consortium (IEC) (Zondervan, K.T.°), GIANT Consortium (Albrecht, E. , Gieger, C. , Grallert, H. , Heid, I.M. , Illig, T. , Müller-Nurasyid, M. , Peters, A. , Thorand, B. , Wichmann, H.-E. ), Nyholt, D.R., Morris, A.P., Montgomery, G.W., Missmer, S.A., Lindgren, C.M.: Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci. Hum. Mol. Genet. 24, 1185-1199 (2015)


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Rückert, I.-M. , Icks, A., Baechle, C., Meisinger, C. °: Versorgung bei Diabetes - Zielerreichung, regionale, sozioökonomische Unterschiede. Diabetes Stoffwechs. Herz 23, 356-361 (2014)

Schaarschmidt, H., Ellinghaus, D., Rodriguez, E., Kretschmer, A. , Baurecht, H., Lipinski, S., Meyer-Hoffert, U., Harder, J., Lieb, W., Novak, N., Fölster-Holst, R., Esparza-Gordillo, J., Marenholz, I., Ruschendorf, F., Hubner, N., Reischl, E. , Waldenberger, M. , Gieger, C. , Illig, T., Kabesch, M., Zhang, X.J., Xiao, F.L., Lee, Y.A., Franke, A., Weidinger, S.°: A genome-wide association study reveals 2 new susceptibility loci for atopic dermatitis. J. Allergy Clin. Immunol., DOI: 10.1016/j.jaci.2015.01.047 (2015)

Schulte, E.C. , Fukumori, A., Mollenhauer, B., Hor, H., Arzberger, T., Perneczky, R., Kurz, A., Diehl-Schmid, J., Hüll, M., Lichtner, P. , Eckstein, G.N. , Zimprich, A., Haubenberger, D., Pirker, W., Brücke, T., Bereznai, B., Molnar, M.J., Lorenzo-Betancor, O., Pastor, P., Peters, A. , Gieger, C. , Estivill, X., Meitinger, T. , Kretzschmar, H.A., Trenkwalder, C., Haass, C., Winkelmann, J. °: Rare variants in β-Amyloid Precursor Protein (APP) and Parkinson's disease. Eur. J. Hum. Genet., DOI: 10.1038/ejhg.2014.300 (2015)

Schunk, M. , Reitmeir, P. , Schipf, S., Völzke, H., Meisinger, C. , Ladwig, K.-H. , Kluttig, A., Greiser, K.H., Berger, K.U., Müller, G., Ellert, U., Neuhauser, H., Tamayo, T., Rathmann, W., Holle, R. °: Health-related quality of life in women and men with type 2 diabetes: A comparison across treatment groups. J. Diab. Complic. 29, 203-211 (2015)


Schwab, S. , Zierer, A. , Schneider, A.E. , Heier, M. , Koenig, W., Kastenmüller, G. , Waldenberger, M. , Peters, A. , Thorand, B. °: Vitamin E supplementation is associated with lower levels of C-reactive protein only in higher dosages and combined with other antioxidants: The Cooperative Health Research in the Region of Augsburg (KORA) F4 study. Br. J. Nutr., DOI: 10.1017/S0007114515000902 (2015)



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Tapper, W.#, Jones, A.V.#, Kralovics, R., Harutyunyan, A.S., Zoi, K., Leung, W., Godfrey, A.L., Guglielmelli, P., Callaway, A., Ward, D., Aranaz, P., White, H.E., Waghorn, K., Lin, F., Chase, A.J., Baxter, E., Maclean, C., Nangalia, J., Chen, E., Evans, P., Short, M., Jack, A., Wallis, L., Oscier, D., Duncombe, A.S., Schuh, A., Mead, A.J., Griffiths, M., Ewing, J., Gale, R.E., Schnittger, S., Haferlach, T., Stegelmann, F., Döhner, K., Grallert, H. , Strauch, K. , Tanaka, T., Bandinelli, S., Giannopoulos, A., Pieri, L., Mannarelli, C., Gisslinger, H., Barosi, G., Cazzola, M., Reiter, A., Harrison, C.N., Campbell, P.J., Green, A.R., Vannucchi, A.M., Cross, N.C.P.°: Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms. Nat. Commun. 6:6691 (2015)

Thaler-Kall, K. °, Peters, A. , Thorand, B. , Grill, E., Autenrieth, C.S. , Horsch, A.D., Meisinger, C. : Description of spatio-temporal gait parameters in elderly people and their association with history of falls: Results of the population-based cross-sectional KORA-Age study. BMC Geriatr. 15:32 (2015)

Tönjes, A.#, Scholz, M.#, Breitfeld, J., Marzi, C. , Grallert, H. , Gross, A., Ladenvall, C., Schleinitz, D., Krause, K.P., Kirsten, H., Laurila, E., Kriebel, J. , Thorand, B. , Rathmann, W., Groop, L.C., Prokopenko, I., Isomaa, B., Beutner, F., Kratzsch, J.K., Thiery, J.J., Faßhauer, M., Klöting, N., Gieger, C. , Blüher, M., Stumvoll, M.W.°, Kovacs, P.°: Genome wide meta-analysis highlights the role of genetic variation in RARRES2 in the regulation of circulating serum chemerin. PLoS Genet. 10:e1004854 (2015)

Turpeinen, H.°, Seppälä, I.J.T., Lyytikäinen, L.P., Raitoharju, E., Hutri-Kähönen, N., Levula, M., Oksala, N.K.J., Waldenberger, M. , Klopp, N.B. , Illig, T. , Mononen, N., Laaksonen, R., Raitakari, O.T., Kähönen, M., Lehtimäki, T., Pesu, M.: A genome-wide expression quantitative trait loci analysis of proprotein convertase subtilisin/kexin enzymes identifies a novel regulatory gene variant for FURIN expression and blood pressure. Hum. Genet. 134, 627-636 (2015)

Virtanen, M.°, Jokela, M., Nyberg, S.T., Madsen, I.E., Lallukka, T., Ahola, K., Alfredsson, L., Batty, G.D., Bjorner, J.B., Borritz, M., Burr, H., Casini, A., Clays, E., de Bacquer, D., Dragano, N., Erbel, R., Ferrie, J.E., Fransson, E.I., Hamer, M., Heikkilä, K., Jockel, K.H., Kittel, F., Knutsson, A., Koskenvuo, M., Ladwig, K.-H. , Lunau, T., Nielsen, M.L., Nordin, M., Oksanen, T., Pejtersen, J.H., Pentti, J., Rugulies, R., Salo, P., Schupp, J., Siegrist, J., Singh-Manoux, A., Steptoe, A., Suominen, S.B., Theorell, T., Vahtera, J., Wagner, G.G., Westerholm, P.J., Westerlund, H., Kivimaki, M.: Long working hours and alcohol use: Systematic review and meta-analysis of published studies and unpublished individual participant data. BMJ Open 350:g7772 (2015)

Vogt, S. °, Mielck, A. , Berger, U., Grill, E., Peters, A. , Döring, A. , Holle, R. , Strobl, R., Zimmermann, A.-K. , Linkohr, B. , Wolf, K. , Kneißl, K., Maier, W. : Neighborhood and healthy aging in a German city: Distances to green space and senior service centers and their associations with physical constitution, disability, and health-related quality of life. Eur. J. Ageing, DOI: 10.1007/s10433-015-0345-0 (2015)

Vogt, S. °, Decke, S.°, de Las Heras Gala, T. °, Linkohr, B. °, Koenig, W. °, Ladwig, K.-H. °, Peters, A. °, Thorand, B. °: Prospective association of vitamin D with frailty status and all-cause mortality in older adults: Results from the KORA-Age study. Prev. Med. 73, 40-46 (2015)

Volaklis, K.A.°, Halle, M.R., Meisinger, C. : Muscular strength as a strong predictor of mortality: A narrative review. Eur. J. Integr. Med., DOI: 10.1016/j.ejim.2015.04.013 (2015)


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Volckmar, A.L.#, Song, J.Y.#, Jarick, I., Pütter, C., Göbel, M., Horn, L.C., Struve, C., Haas, K., Knoll, N., Grallert, H. , Illig, T. , Reinehr, T., Wang, H.J., Hebebrand, J., Hinney, A.°: Fine mapping of a GWAS-derived obesity candidate region on chromosome 16p11.2. PLoS ONE 10:e0125660 (2015)

von Eisenhart Rothe, A. #, Hutt, F. #, Baumert, J.J. , Breithardt, G., Goette, A., Kirchhof, P., Ladwig, K.-H. °: Depressed mood amplifies heart-related symptoms in persistent and paroxysmal atrial fibrillation patients: A longitudinal analysis-data from the German competence network on atrial fibrillation. Europace, DOI: 10.1093/europace/euv018 (2015)

Voss, A.°, Schroeder, R., Heitmann, A., Peters, A. , Perz, S.: Short-term heart rate variability-influence of gender and age in healthy subjects. PLoS ONE 10:e0118308 (2015)


Wanner, M., Richard, A., Martin, B.W., Linseisen, J. , Rohrmann, S.°: Associations between objective and self-reported physical activity and vitamin D serum levels in the US population. Cancer Causes Control, DOI: 10.1007/s10552-015-0563-y (2015)


Williams, K.M., Verhoeven, V.J., Cumberland, P.M., Bertelsen, G., Wolfram, C., Buitendijk, G.H., Hofman, A., van Duijn, C.M., Vingerling, J.R., Kuijpers, R.W., Höhn, R., Mirshahi, A., Khawaja, A.P., Luben, R.N., Erke, M.G., von Hanno, T., Mahroo, O., Hogg, R., Gieger, C. , Cougnard-Grégoire, A., Anastasopoulos, E., Bron, A., Dartigues, J.F., Korobelnik, J.F., Creuzot-Garcher, C., Topouzis, F., Delcourt, C., Rahi, J.S., Meitinger, T., Fletcher, A., Foster, P.J., Pfeiffer, N., Klaver, C.C., Hammond, C.J.°: Prevalence of refractive error in Europe: The European Eye Epidemiology (E3) consortium. Eur. J. Epidemiol. 30, 305-315 (2015)


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Zimmermann, E., Ängquist, L.H., Mirza, S.S., Zhao, J.H., Chasman, D.I., Fischer, K., Qi, Q., Smith, A.V., Thinggaard, M., Jarczok, M.N., Nalls, M.A., Trompet, S., Timpson, N.J., Schmidt, B., Jackson, A.U., Lyytikäinen, L.P., Verweij, N., Müller-Nurasyid, M. , Vikström, M., Marques-Vidal, P., Wong, A., Meidtner, K., Middelberg, R.P., Strawbridge, R.J., Christiansen, L., Kyvik, K.O.H.M., Hamsten, A., Jääskeläinen, T., Tjönneland, A.M., Eriksson, J.G., Whitfield, J.B., Boeing, H., Hardy, R., Vollenweider, P., Leander, K., Peters, A. , van der Harst, P., Kumari, M., Lehtimäki, T., Meirhaeghe, A., Tuomilehto, J.O.I., Jockel, K.H., Ben-Shlomo, Y., Sattar, N.A., Baumeister, S.E., Davey Smith, G., Casas, J.P., Houston, D.K., März, W., Christensen, K., Gudnason, V.G., Hu, F.B., Metspalu, A., Ridker, P.M., Wareham, N.J., Loos, R.J.F., Tiemeier, H.M., Sonestedt, E., Sørensen, T.I.A.°: Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults. Obes. Rev. 16, 327-340 (2015)

Zimmermann, H.#°, Hagenfeld, D.#, Diercke, K., El-Sayed, N., Fricke, J., Greiser, K.H., Kuhnisch, J., Linseisen, J. , Meisinger, C. , Pischon, N., Pischon, T., Samietz, S., Schmitter, M., Steinbrecher, A., Kim, T.S., Becher, H.: Pocket depth and bleeding on probing and their associations with dental, lifestyle, socioeconomic and blood variables: A cross-sectional, multicenter feasibility study of the German National Cohort. BMC Oral Health 15:7 (2015)


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Auer, M., Tao, X., Roepke, Y., Stalla, G.K., Stieg, M., van Caenegem, E., Prehn, C. , Wang-Sattler, R. , Adamski, J. , T'sjoen, G.: Pilot study on the effects of cross-sex hormone treatment in transsexual persons on metabolism by means of metabolomics profiling. Poster: Exp. Clin. Endocrinol. Diabet. 123 (2015)



Derdak, S., Sabrautzki, S. , Hrabě de Angelis, M. , Gut, M.O., Gut, I.G., Beltran, S.°: Genomic characterization of mutant laboratory mouse strains by exome sequencing and annotation lift-over. BMC Genomics 16:351 (2015)


Ferrari, U. , Künzel, H.E.°, Tröndle, K. , Rottenkolber, M., Kohn, D., Fugmann, M. , Banning, F. , Weise, M. , Sacco, V. , Hasbargen, U., Hutter, S., Parhofer, K.G. , Kloiber, S., Ising, M., Seissler, J. , Lechner, A. : Poor sleep quality is associated with impaired glucose tolerance in women after gestational diabetes. J. Psychiatr. Res., DOI: 10.1016/j.jpsychires.2015.02.012 (2015)



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Holm, T.A., Wulf-Joansson, H., Hvidtsen, S., Jorgensen, P.T., Schlosser, A., Pilecki, B., Ormhoj, M., Moeller, J.B., Hoannsen, C., Baun, C., Andersen, T., Schneider, J.P., Hegermann, J., Ochs, M., Götz, A.A., Schulz, H., Hrabě de Angelis, M. , Vestbo, J., Holmskov, U., Sorensen, G.L.°: Characterization of spontaneous airspace enlargement in mice lacking microfibrillar-associated protein 4. Am. J. Physiol. Lung Cell Mol. Physiol., DOI: 10.1152/ajplung.00351.2014 (2015)




Kunze, S. , Dalke, C. , Fuchs, H. , Klaften, M. , Rössler, U., Hornhardt, S., Gomolka, M., Puk, O. , Sabrautzki, S., Kulka, U., Hrabě de Angelis, M. , Graw, J. °: New mutation in the mouse Xpd/Ercc2 gene leads to recessive cataracts. PLoS ONE 10:e0125304 (2015)


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Moreth, K. #°, Afonso, L.C. #, Fuchs, H. , Gailus-Durner, V. , Katus, H.A., Bekerdjian, R., Lehmann, L., Hrabě de Angelis, M. : High throughput phenotyping of left and right ventricular cardiomyopathy in calcineurin transgene mice. Int. J. Cardiovasc. Imaging 31, 669-679 (2015)


Perez, L.°, Wolf, K. , Hennig, F., Penell, J., Basagana, X., Aguilera, I., Agis, D., Beelen, R., Brunekreef, B., Cyrys, J., Fuks, K.B., Adam, M., Baldassare, D., Cirach, M., Elosua, R., Dratva, J., Hampel, R. , Koenig, W., Marrugat, J., de Faire, U., Pershagen, G., Probst-Hensch, N.M., de Nazelle, A., Nieuwenhuijsen, M.J., Rathmann, W., Rivera, M., Seissler, J. , Schindler, C., Thierry, J., Hoffmann, B., Peters, A. , Künzli, N.: Air pollution and atherosclerosis: A cross-sectional analysis of four European cohort studies in the ESCAPE study. Environ. Health Perspect., DOI: 10.1289/ehp.1307711 (2015)



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Rathkolb, B. °, Klempt, M., Sabrautzki, S. , Michel, D. , Klaften, M. , Laufs, J., Sedlmeier, R., Hans, W. , Fuchs, H. , Muckenthaler, M.U., Horsch, M. , Campagna, D.R., Fleming, M., Hrabě de Angelis, M. , Wolf, E., Aigner, B.: Screen for alterations of iron related parameters in N-ethyl-N-nitrosurea-treated mice identified mutant lines with increased plasma ferritin levels. Biometals 28, 293-306 (2015)




Schmitt, S. , Eberhagen, C. , Weber, S. , Aichler, M. , Zischka, H. °: Isolation of mitochondria from cultured cells and liver tissue biopsies for molecular and biochemical analyses. Methods Mol. Biol. 1295, 87-97 (2015)


Sinreih, M., Zukunft, S. , Sosič, I., Cesar, J., Gobec, S., Adamski, J. , Lanisnik Rizner, T.: Combined liquid chromatography - tandem mass spectrometry analysis of progesterone metabolites. PLoS ONE 10:e0117984 (2015)





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Baumert, J.J. #, Huang, J.#, McKnight, B.#, Sabater-Lleal, M.#, Steri, M.#, Chu, A.Y., Trompet, S., Lopez, L.M., Fornage, M., Teumer, A., Tang, W., Rudnicka, A.R., Mälarstig, A., Hottenga, J.J., Kavousi, M., Lahti, J., Tanaka, T., Hayward, C., Huffman, J.E., Morange, P.E., Rose, L.M., Basu, S., Rumley, A., Stott, D.J., Buckley, B.M., de Craen, A.J., Sanna, S., Masala, M., Biffar, R., Homuth, G., Silveira, A., Sennblad, B., Goel, A., Watkins, H., Müller-Nurasyid, M. , Rückerl, R. , Taylor, K., Chen, M., de Geus, E.J., Hofman, A., Witteman, J.C., de Maat, M.P.M., Palotie, A., Davies, G., Siscovick, D.S., Kolcic, I., Wild, S.H., Song, J., McArdle, W.L., Ford, I., Sattar, N., Schlessinger, D., Grotevendt, A., Franzosi, M.G., Illig, T. , Waldenberger, M., Lumley, T., Tofler, G.H., Willemsen, G., Uitterlinden, A.G., Rivadeneira, F., Räikkönen, K., Chasman, D.I., Folsom, A.R., Lowe, G.D., Westendorp, R.G., Slagboom, P.E., Cucca, F., Wallaschofski, H., Strawbridge, R.J., Seedorf, U., Koenig, W., Bis, J.C., Mukamal, K.J., van Dongen, J., Widen, E., Franco, O.H., Starr, J.M., Liu, K., Ferrucci, L., Polašek, O., Wilson, J.F., Oudot-Mellakh, T., Campbell, H., Navarro, P., Bandinelli, S., Eriksson, J., Boomsma, D.I., Dehghan, A., Clarke, R., Hamsten, A., Boerwinkle, E., Jukema, J.W., Naitza, S., Ridker, P.M., Völzke, H., Deary, I.J., Reiner, A.P., Tregouet, D., O'Donnell, C.J., Strachan, D.P., Peters, A. °, Smith, N.L.°: No evidence for genome-wide interactions on plasma fibrinogen by smoking, alcohol consumption and body mass index: Results from meta-analyses of 80,607 subjects. PLoS ONE 9:e111156 (2014)

Baurecht, H.#, Hotze, M.#, Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C. , Hubner, N., Illig, T. , Irvine, A.D., Kabesch, M., Lee, Y.A., Lieb, W., Marenholz, I., McLean, W.H., Morris, D.W., Mrowietz, U., Nair, R.P., Nöthen, M.M., Novak, N., O'Regan, G.M., Schreiber, S., Smith, C., Strauch, K. , Stuart, P.E., Trembath, R., Tsoi, L.C., Weichenthal, M., Barker, J., Elder, J.T., Weidinger, S.°, Cordell, H.J., Brown, S.J.°: Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms. Am. J. Hum. Genet. 96, 104-120 (2015)

Brugger, M. , Strauch, K. °: Fast linkage analysis with MOD scores using algebraic calculation. Hum. Hered. 78, 179-194 (2014)



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Interleukin 1 Genetics Consortium, Freitag, D.F., Butterworth, A.S., Willeit, P., Howson, J.M.M., Burgess, S.L., Kaptoge, S.K., Young, R., Ho, W.K., Wood, A.M., Sweeting, M., Spackman, S., Staley, J.R., Ramond, A., Harshfield, E., Nielsen, S.F., Grande, P., Lange, L.A., Bown, M., Jones, G.T., Scott, R.A.H., Bevan, S.N., Porcu, E., Thorleifsson, G., Zeng, L.M., Kessler, T., Nikpay, M., Do, R., Zhang, W., Hopewell, J.C., Kleber, M.E., Delgado, G.E., Nelson, C.P., Goel, A., Bis, J.C.M., Dehghan, A.J., Ligthart, S., Smith, A.V., Qu, L., van 'T Hof, F., de Bakker, P.I.W., Baas, A.F., van Rij, A.M., Tromp, G., Kuivaniemi, H., Ritchie, M.D., Verma, S.S., Crawford, D.C., Malinowski, J., de Andrade, M., Kullo, I.J., Peissig, P.L., McCarty, C.A., Bottinger, E.P., Gottesman, O., Crosslin, D.R., Carrell, D.S., Rasmussen-Torvik, L.J., Pacheco, J.A., Huang, J., Timpson, N.J., Kettunen, J.A., Ala-Korpela, M., Mitchell, G.F., Parsa, A., Wilkinson, I.B., Gorski, M., Li, Y., Franceschini, N.C., Keller, M.F., Ganesh, S.K., Langefeld, C.D., Bruijn, L., Brown, M.A., Evans, D.M.D., Baltic, S., Ferreira, M.A.R., Baurecht, H.J., Weidinger, S., Franke, A., Lubitz, S.A., Müller-Nurasyid, M. , Felix, J.F., Smith, N.L., Sudman, M., Thompson, S.D., Zeggini, E., Panoutsopoulou, K., Nalls, M.A., Singleton, A.B., Polychronakos, C., Bradfield, J.P., Hakonarson, H.H., Easton, D.F., Thompson, D.J., Tomlinson, I.P.M., Dunlop, M.G., Hemminki, K.L., Morgan, G., Eisen, T., Goldschmidt, H.P., Allan, J.M., Henrion, M., Whiffin, N., Wang, Y., Chubb, D., Iles, M.M., Bishop, D.T., Law, M.H., Hayward, N.K., Luo, Y., Nejentsev, S., Barbalic, M., Crossman, D.C., Sanna, S., Soranzo, N., Markus, H.S., Wareham, N.J., Rader, D.J., Reilly, M.P., Assimes, T.L., Harris, T.B., Hofman, A., Franco, O.H., Gudnason, V.G., Tracy, R.P., Psaty, B.M., Farrall, M.J., Watkins, H., Hall, A.S., Samani, N.J., Marz, W., Clarke, R., Collins, R.E., Kooner, J.S., Chambers, J.C., Kathiresan, S., McPherson, R., Erdmann, J., Kastrati, A., Schunkert, H., Stefansson, K., Thorsteinsdottir, U., Walston, J.D., Tybjærg-Hansen, A., Alam, D.S., Al Shafi Majumder, A., Angelantonio, E.D., Chowdhury, R., Nordestgaard, B.G., Saleheen, D., Thompson, S.G., Danesh, J., Houlston, R.S.°: Cardiometabolic effects of genetic upregulation of the interleukin 1 receptor antagonist: A mendelian randomisation analysis. Lancet Diabet. Endocrinol. 3, 243-253 (2015)

Kirsten, H., Scholz, M., Kovacs, P., Grallert, H. , Peters, A. , Strauch, K. , Frank, J., Rietschel, M., Nöthen, M.M., Witt, H., Rosendahl, J.°: Genetic variants of lipase activity in chronic pancreatitis. Gut, DOI: 10.1136/gutjnl-2015-309521 (2015)


Kunz, M.°, König, I.R., Schillert, A., Kruppa, J., Ziegler, A., Grallert, H. , Müller-Nurasyid, M. , Lieb, W., Franke, A., Ranki, A., Panelius, J., Koskenmies, S., Hasan, T., Kere, J., Rönn, A.C., Simon, J.C., Schmidt, E., Wenzel, J., Tüting, T., Landsberg, J., Zeller, T., Blankenberg, S., Gläser, R., Patsinakidis, N., Kuhn, A., Ibrahim, S.M.: Genome-wide association study identifies new susceptibility loci for cutaneous lupus erythematosus. Exp. Dermatol., DOI: 10.1111/exd.12708 (2015)


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Lal, D.#, Ruppert, A.K.#, Trucks, H., Schulz, H., de Kovel, C.G.F., Kasteleijn-Nolst Trenité, D., Sonsma, A.C., Koeleman, B.P., Lindhout, D., Weber, Y.G., Lerche, H., Kapser, C., Schankin, C.J., Kunz, W.S., Surges, R., Elger, C.E., Gaus, V., Schmitz, B., Helbig, I., Muhle, H., Stephani, U., Klein, K.M., Rosenow, F., Neubauer, B.A., Reinthaler, E.M., Zimprich, F., Feucht, M., Møller, R.S., Hjalgrim, H., de Jonghe, P., Suls, A., Lieb, W., Franke, A., Strauch, K. , Gieger, C. , Schurmann, C., Schminke, U., Nürnberg, P., Sander, T.°: Burden analysis of rare microdeletions suggests a strong impact of neurodevelopmental genes in genetic generalised epilepsies. PLoS Genet. 11:e1005226 (2015)



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Nead, K.T., Li, A., Wehner, M.R., Neupane, B., Gustafsson, S., Butterworth, A.S., Engert, J.C., Davis, A.D., Hegele, R.A., Miller, R., den Hoed, M., Khaw, K.T., Kilpeläinen, T.O., Wareham, N., Edwards, T.L., Hallmans, G., Varga, T.V., Kardia, S.L., Smith, J.A., Zhao, W., Faul, J.D., Weir, D.R., Mi, J., Xi, B., Quinteros, S.C., Cooper, C., Sayer, A.A., Jameson, K., Grøntved, A., Fornage, M., Sidney, S., Hanis, C.L., Highland, H.M., Häring, H.-U., Heni, M., Lasky-Su, J., Weiss, S.T., Gerhard, G.S., Still, C., Melka, M.M., Pausova, Z., Paus, T., Grant, S.F.A., Hakonarson, H., Price, R.A., Wang, K., Scherag, A., Hebebrand, J., Hinney, A., BIoBank Japan (Meyre, D.°), AGEN-BMI, GIANT Consortium (Albrecht, E. , Gieger, C. , Grallert, H., Heid, I.M. , Illig, T. , Müller-Nurasyid, M. , Peters, A. , Thorand, B. , Wichmann, H.-E. ), Franks, P.W., Frayling, T.M., McCarthy, M.I., Hirschhorn, J.N., Loos, R.J., Ingelsson, E., Gerstein, H.C., Yusuf, S., Beyene, J., Anand, S.S.: Contribution of common non-synonymous variants in PCSK1 to body mass index variation and risk of obesity: A systematic review and meta-analysis with evidence from up to 331 175 individuals. Hum. Mol. Genet., DOI: 10.1093/hmg/ddv097 (2015)

Pers, T.H., Karjalainen, J.M., Chan, Y., Westra, H.J., Wood, A.R., Yang, J., Lui, J.C., Vedantam, S., Gustafsson, S., Esko, T., Frayling, T., Speliotes, E.K., EUMODIC Consortium (Albrecht, E. , Gieger, C. , Grallert, H. , Heid, I.M. , Illig, T. , Müller-Nurasyid, M. , Peters, A. , Thorand, B. , Wichmann, H.-E. ), Boehnke, M., Raychaudhuri, S., Fehrmann, R.S.N., Hirschhorn, J.N.°, Franke, L.°: Biological interpretation of genome-wide association studies using predicted gene functions. Nat. Commun. 6:5890 (2015)

Quante, A.S. , Whittemore, A.S., Shriver, T., Hopper, J.L., Strauch, K. , Terry, M.B.°: Practical problems with clinical guidelines for breast cancer prevention based on remaining lifetime risk. J. Natl. Cancer Inst. 107:djv124 (2015)

Rahmioglu, N., MacGregor, S., Drong, A.W., Hedman, A.K., Harris, H.R., Randall, J.C., Prokopenko, I., International Endogene Consortium (IEC) (Zondervan, K.T.°), GIANT Consortium (Albrecht, E. , Gieger, C. , Grallert, H. , Heid, I.M. , Illig, T. , Müller-Nurasyid, M. , Peters, A. , Thorand, B. , Wichmann, H.-E. ), Nyholt, D.R., Morris, A.P., Montgomery, G.W., Missmer, S.A., Lindgren, C.M.: Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci. Hum. Mol. Genet. 24, 1185-1199 (2015)



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Tapper, W.#, Jones, A.V.#, Kralovics, R., Harutyunyan, A.S., Zoi, K., Leung, W., Godfrey, A.L., Guglielmelli, P., Callaway, A., Ward, D., Aranaz, P., White, H.E., Waghorn, K., Lin, F., Chase, A.J., Baxter, E., Maclean, C., Nangalia, J., Chen, E., Evans, P., Short, M., Jack, A., Wallis, L., Oscier, D., Duncombe, A.S., Schuh, A., Mead, A.J., Griffiths, M., Ewing, J., Gale, R.E., Schnittger, S., Haferlach, T., Stegelmann, F., Döhner, K., Grallert, H. , Strauch, K. , Tanaka, T., Bandinelli, S., Giannopoulos, A., Pieri, L., Mannarelli, C., Gisslinger, H., Barosi, G., Cazzola, M., Reiter, A., Harrison, C.N., Campbell, P.J., Green, A.R., Vannucchi, A.M., Cross, N.C.P.°: Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms. Nat. Commun. 6:6691 (2015)


Zimmermann, E., Ängquist, L.H., Mirza, S.S., Zhao, J.H., Chasman, D.I., Fischer, K., Qi, Q., Smith, A.V., Thinggaard, M., Jarczok, M.N., Nalls, M.A., Trompet, S., Timpson, N.J., Schmidt, B., Jackson, A.U., Lyytikäinen, L.P., Verweij, N., Müller-Nurasyid, M. , Vikström, M., Marques-Vidal, P., Wong, A., Meidtner, K., Middelberg, R.P., Strawbridge, R.J., Christiansen, L., Kyvik, K.O.H.M., Hamsten, A., Jääskeläinen, T., Tjönneland, A.M., Eriksson, J.G., Whitfield, J.B., Boeing, H., Hardy, R., Vollenweider, P., Leander, K., Peters, A. , van der Harst, P., Kumari, M., Lehtimäki, T., Meirhaeghe, A., Tuomilehto, J.O.I., Jockel, K.H., Ben-Shlomo, Y., Sattar, N.A., Baumeister, S.E., Davey Smith, G., Casas, J.P., Houston, D.K., März, W., Christensen, K., Gudnason, V.G., Hu, F.B., Metspalu, A., Ridker, P.M., Wareham, N.J., Loos, R.J.F., Tiemeier, H.M., Sonestedt, E., Sørensen, T.I.A.°: Is the adiposity-associated FTO gene variant related to all-cause mortality independent of adiposity? Meta-analysis of data from 169,551 Caucasian adults. Obes. Rev. 16, 327-340 (2015)


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Adomako, D., Gibrilla, A.°, Maloszewski, P. , Ganyaglo, S.Y., Rai, S.: Tracing stable isotopes (δ2H and δ18O) from meteoric water to groundwater in the Densu River basin of Ghana. Environ. Monit. Assess. 187:264 (2015)

Down, A., Schreglmann, K. , Plata, D.L., Elsner, M. , Warner, N.R., Vengosh, A., Moore, K., Coleman, D., Jackson, R.B.°: Pre-drilling background groundwater quality in the Deep River Triassic Basin of central North Carolina, USA. Appl. Geochem., DOI: 10.1016/j.apgeochem.2015.01.018 (2015)

Eckert, D., Kürzinger, P. , Bauer, R.D. , Griebler, C. , Cirpka, O.A.°: Fringe-controlled biodegradation under dynamic conditions: Quasi 2-D flow-through experiments and reactive-transport modeling. J. Contam. Hydrol. 172, 100-111 (2015)

Einsiedl, F.°, Pilloni, G. , Ruth-Anneser, B. , Lueders, T. , Griebler, C. : Spatial distributions of sulphur species and sulphate-reducing bacteria provide insights into sulphur redox cycling and biodegradation hot-spots in a hydrocarbon-contaminated aquifer. Geochim. Cosmochim. Acta 156, 207-221 (2015)

Griebler, C. °, Avramov, M. °: Groundwater ecosystem services: A review. Freshw. Sci. 34, 355-367 (2015)

Gründger, F., Jimenez, N., Thielemann, T., Straaten, N., Lüders, T. , Richnow, H.-H., Krüger, M.°: Microbial methane formation in deep aquifers of a coal-bearing sedimentary basin, Germany. Front. Microbiol. 6:200 (2015)

Höss, S.°, Fritzsche, A., Meyer, C. , Bosch, J. , Meckenstock, R.U. , Totsche, K.U.: Size- and composition-dependent toxicity of synthetic and soil-derived Fe oxide colloids for the nematode Caenorhabditis elegans. Environ. Sci. Technol. 49, 544-552 (2015)

Klaus, J.°, Chun, K., Stumpp, C. : Temporal trends in δ18O composition of precipitation in Germany: Insights from time series modelling and trend analysis. Hydrol. Process., DOI: 10.1002/hyp.10395 (2014)

Rühle, F. , von Netzer, F. , Lueders, T. , Stumpp, C. °: Response of transport parameters and sediment microbiota to water table fluctuations in laboratory columns. Vadose Zone J. 14, DOI: 10.2136/vzj2014.09.0116 (2015)

Schürner, H.K.V. , Seffernick, J.L., Grzybkowska, A., Dybała-Defratyka, A., Wackett, L.P., Elsner, M. °: Characteristic isotope fractionation patterns in s-triazine degradation have their origin in multiple protonation options in the s-triazine hydrolase trzn. Environ. Sci. Technol. 49, 3490-3498 (2015)

Stoewer, M., Knöller, K., Stumpp, C. °: Tracing freshwater nitrate sources in pre-alpine groundwater catchments using environmental tracers. J. Hydrol. 524, 753-767 (2015)

Zhang, L. , Jungblut, A.D.°, Hawes, I., Andersen, D.T., Sumner, D.Y., Mackey, T.J.: Cyanobacterial diversity in benthic mats of the McMurdo Dry Valley lakes, Antarctica. Polar Biol., DOI: 10.1007/s00300-015-1669-0 (2015)


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Becker, C. °, Holle, R. , Stollenwerk, B. : The excess health care costs of KardioPro, an integrated care program for coronary heart disease prevention. Health Policy, DOI: 10.1016/j.healthpol.2015.01.012 (2015)

Bozorgmehr, K.°, San Sebastian, M., Brenner, H., Razum, O., Maier, W. , Saum, K.U., Holleczek, B., Miksch, A., Szecsenyi, J.: Analysing horizontal equity in enrolment in Disease Management Programmes for coronary heart disease in Germany 2008–2010. Int. J. Equity Health 14:28 (2015)

de Wit, G.A.°, Over, E.A., Schmid, B.V., van Bergen, J.E., van den Broek, I.V., van der Sande, M.A., Welte, R., Op de Coul, E.L., Kretzschmar, M.E.: Chlamydia screening is not cost-effective at low participation rates: Evidence from a repeated register-based implementation study in the Netherlands. Sex. Transm. Dis., DOI: 10.1136/sextrans-2014-051677 (2015)

Dondorp, W.°, de Wert, G., Bombard, Y., Bianchi, D.W., Bergmann, C., Borry, P., Chitty, L.S., Fellmann, F., Forzano, F., Hall, A., Henneman, L., Howard, H.C., Lucassen, A., Ormond, K., Peterlin, B., Radojkovic, D., Rogowski, W.H. , Soller, M., Tibben, A., Tranebjærg, L., van El, C.G., Cornel, M.C.: Non-invasive prenatal testing for aneuploidy and beyond: Challenges of responsible innovation in prenatal screening. Eur. J. Hum. Genet., DOI: 10.1038/ejhg.2015.57 (2015)

Dondorp, W.°, de Wert, G., Bombard, Y., Bianchi, D.W., Bergmann, C., Borry, P., Chitty, L.S., Fellmann, F., Forzano, F., Hall, A., Henneman, L., Howard, H.C., Lucassen, A., Ormond, K., Peterlin, B., Radojkovic, D., Rogowski, W.H. , Soller, M., Tibben, A., Tranebjærg, L., van El, C.G., Cornel, M.C.: Non-invasive prenatal testing for aneuploidy and beyond: Challenges of responsible innovation in prenatal screening. Summary and recommendations. Eur. J. Hum. Genet., DOI: 10.1038/ejhg.2015.56 (2015)

Hofmeister, C., Maier, W. , Mielck, A. , Stahl, L., Breckenkamp, J.°, Razum, O.: Regionale Deprivation in Deutschland: Bundesweite Analyse des Zusammenhangs mit Mortalität unter Verwendung des ‚German Index of Multiple Deprivation (GIMD)‘. Gesundheitswesen, DOI: 10.1055/s-0034-1390421 (2015)

Huber, M.B. °, Wacker, M. , Vogelmeier, C.F., Leidl, R. : Excess costs of comorbidities in chronic obstructive pulmonary disease: A systematic review. PLoS ONE 10:e0123292 (2015)

Idler, N. , Teuner, C.M. , Hunger, M. , Holle, R. °, Ortlieb, S. , Schulz, H. , Bauer, C.P., Hoffmann, U., Koletzko, S., Lehmann, I., von Berg, A., Berdel, D., Hoffmann, B., Schaaf, B., Heinrich, J. , Wolfenstetter, S.B.: The association between physical activity and healthcare costs in children - results from the GINIplus and LISAplus cohort studies. BMC Public Health 15:437 (2015)

Italia, S. °, Brand, H., Heinrich, J. , Berdel, D., von Berg, A., Wolfenstetter, S.B. : Utilization of Complementary and Alternative Medicine (CAM) among children from a German birth cohort (GINIplus): Patterns, costs, and trends of use. BMC Complement. Altern. Med. 15:569 (2015)

Kirchberger, I. °, Hunger, M. , Stollenwerk, B. , Seidl, H. , Burkhardt, K. , Kuch, B., Meisinger, C. , Holle, R. : Effects of a 3-year nurse-based case management in aged patients with acute myocardial infarction on rehospitalisation, mortality, risk factors, physical functioning and mental health. A secondary analysis of the randomized controlled KORINNA study. PLoS ONE 10:e0116693 (2015)


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Kirsch, F. °: A systematic review of quality and cost-effectiveness derived from Markov models evaluating smoking cessation interventions in patients with chronic obstructive pulmonary disease. Expert Rev. Pharmacoecon. Outcomes Res. 15, 301-316 (2015)

Lotty, E.Y. , Hämmerling, C., Mielck, A. °: Gesundheitszustand von Menschen ohne Krankenversicherung und von Menschen ohne legalen Aufenthaltsstatus: Analyse von Daten der Malteser Migranten Medizin (MMM) in München. Gesundheitswesen, DOI: 10.1055/s-0034-1395646 (2015)

Schott, K. , Hunger, M. , Lampert, T., Spengler, S., Mess, F., Mielck, A. °: Soziale Unterschiede in der körperlich-sportlichen Aktivität bei Jugendlichen: Analyse der MoMo-Daten mithilfe der metabolischen Äquivalente (MET). Gesundheitswesen, DOI: 10.1055/s-0034-1398556 (2015)

Schunk, M. , Reitmeir, P. , Schipf, S., Völzke, H., Meisinger, C. , Ladwig, K.-H. , Kluttig, A., Greiser, K.H., Berger, K.U., Müller, G., Ellert, U., Neuhauser, H., Tamayo, T., Rathmann, W., Holle, R. °: Health-related quality of life in women and men with type 2 diabetes: A comparison across treatment groups. J. Diab. Complic. 29, 203-211 (2015)


Severin, F. °, Stollenwerk, B. , Holinski-Feder, E., Meyer, E. , Heinemann, V., Giessen-Jung, C., Rogowski, W.H.: Economic evaluation of genetic screening for Lynch syndrome in Germany. Genet. Med., DOI: 10.1038/gim.2014.190 (2015)


Stollenwerk, B. °, Bartmus, T. , Klug, F. , Stock, S., Müller, D.: Cost-effectiveness of hip protector use on a geriatric ward in Germany: A Markov model. Osteoporos. Int. 26, 1367-1379 (2015)

Stollenwerk, B. °, Welchowski, T. , Vogl, M. , Stock, S.: Cost-of-illness studies based on massive data: A prevalence-based, top-down regression approach. Eur. J. Health Econ., DOI: 10.1007/s10198-015-0667-z (2015)

Vogt, S. °, Mielck, A. , Berger, U., Grill, E., Peters, A. , Döring, A. , Holle, R. , Strobl, R., Zimmermann, A.-K. , Linkohr, B. , Wolf, K. , Kneißl, K., Maier, W. : Neighborhood and healthy aging in a German city: Distances to green space and senior service centers and their associations with physical constitution, disability, and health-related quality of life. Eur. J. Ageing, DOI: 10.1007/s10433-015-0345-0 (2015)



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Ahting, U., Mayr, J.A., Vanlander, A.V.I., Hardy, S.A., Santra, S., Makowski, C.C., Alston, C.L., Zimmermann, F.A., Abela, L., Plecko, B.R., Rohrbach, M.A., Spranger, S., Seneca, S.H., Rolinski, B., Hagendorff, A., Hempel, M.S., Sperl, W.J.K., Meitinger, T. , Smet, J.E., Taylor, R.W., van Coster, R.N.A., Freisinger, P., Prokisch, H. , Haack, T.B. °: Clinical, biochemical, and genetic spectrum of seven new patients with NFU1 deficiency. Front. Genet. 6:123 (2015)


Baertling, F., Haack, T.B. , Rodenburg, R.J., Schaper, J., Seibt, A., Strom, T.-M. , Meitinger, T. , Mayatepek, E., Hadzik, B., Selcan, G., Prokisch, H. °, Distelmaier, F.°: MRPS22 mutation causes fatal neonatal lactic acidosis with brain and heart abnormalities. Neurogenetics, DOI: 10.1007/s10048-015-0440-6 (2015)


Behr, E.R.°, Savio-Galimberti, E., Barc, J., Holst, A.G., Petropoulou, E., Prins, B.P., Jabbari, J., Torchio, M., Berthet, M., Mizusawa, Y., Yang, T., Nannenberg, E.A., Dagradi, F., Weeke, P., Bastiaenan, R., Ackerman, M.J., Haunso, S., Leenhardt, A., Kääb, S. , Probst, V., Redon, R., Sharma, S., Wilde, A.A., Tfelt-Hansen, J., Schwartz, P., Roden, D.M., Bezzina, C.R., Olesen, M.S., Darbar, D., Guicheney, P., Crotti, L. , Jamshidi, Y.: Role of common and rare variants in SCN10A: Results from the Brugada syndrome QRS locus gene discovery collaborative study. Cardiovasc. Res., DOI: 10.1093/cvr/cvv042 (2015)

Beleggia, F., Li, Y., Fan, J., Elcioğlu, N.H., Toker, E., Wieland, T. , Maumenee, I.H., Akarsu, N.A., Meitinger, T., Strom, T.-M. , Lang, R., Wollnik, B.°: CRIM1 haploinsufficiency causes defects in eye development in human and mouse. Hum. Mol. Genet. 24, 2267-2273 (2015)

Bramswig, N.C.°, Lüdecke, H.J., Alanay, Y., Albrecht, B., Barthelmie, A., Boduroglu, K., Braunholz, D., Caliebe, A., Chrzanowska, K.H., Czeschik, J.C., Endele, S.U., Graf, E. , Guillén-Navarro, E., Kiper, P.O.S., López-González, V., Parenti, I., Pozojevic, J., Ü̈tine, G.E., Wieland, T. , Kaiser, F.J., Wollnik, B., Strom, T.-M., Wieczorek, D.: Exome sequencing unravels unexpected differential diagnoses in individuals with the tentative diagnosis of Coffin–Siris and Nicolaides–Baraitser syndromes. Hum. Genet. 134, 553-568 (2015)

Brea-Calvo, G., Haack, T.B. , Karall, D., Ohtake, A., Invernizzi, F., Carrozzo, R., Kremer, L. , Dusi, S., Fauth, C., Scholl-Bürgi, S., Graf, E. , Ahting, U. , Resta, N., Laforgia, N., Verrigni, D., Okazaki, Y., Kohda, M., Martinelli, D., Freisinger, P., Strom, T.-M. , Meitinger, T. , Lamperti, C., Lacson, A., Navas, P., Mayr, J.A., Bertini, E., Murayama, K., Zeviani, M., Prokisch, H. °, Ghezzi, D.°: COQ4 mutations cause a broad spectrum of mitochondrial disorders associated with CoQ10 deficiency. Am. J. Hum. Genet. 96, 309-317 (2015)


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Distelmaier, F.°, Haack, T.B. , Catarino, C.B., Gallenmüller, C., Rodenburg, R.J.T., Strom, T.-M. , Baertling, F., Meitinger, T. , Mayatepek, E., Prokisch, H. °, Klopstock, T.: MRPL44 mutations cause a slowly progressive multisystem disease with childhood-onset hypertrophic cardiomyopathy. Neurogenetics, DOI: 10.1007/s10048-015-0444-2 (2015)

Escott-Price, V., Nalls, M.A., Morris, H.R., Lubbe, S., Brice, A., Gasser, T., Heutink, P., Wood, N.W., Hardy, J., Singleton, A.B., Williams, N.M.°, International Parkinson's Disease Genomics Consortium (IPDGC) (Illig, T., Lichtner, P. ): Polygenic risk of Parkinson disease is correlated with disease age at onset. Ann. Neurol. 77, 582-591 (2015)

Evangelisti, C.°, de Biase, D., Kurelac, I., Ceccarelli, C., Prokisch, H. , Meitinger, T. , Caria, P., Vanni, R., Romeo, G., Tallini, G., Gasparre, G., Bonora, E.: A mutation screening of oncogenes, tumor suppressor gene TP53 and nuclear encoded mitochondrial complex I genes in oncocytic thyroid tumors. BMC Cancer 15:157 (2015)

Falk, M.J.°, Shen, L., Gonzalez, M., Leipzig, J., Lott, M.T., Stassen, A.P., Diroma, M.A., Navarro-Gomez, D., Yeske, P., Bai, R., Boles, R.G., Brilhante, V., Ralph, D., DaRe, J.T., Shelton, R., Terry, S.F., Zhang, Z., Copeland, W.C., van Oven, M., Prokisch, H. , Wallace, D.C., Attimonelli, M., Krotoski, D., Zuchner, S., Gai, X.°: Mitochondrial Disease Sequence Data Resource (MSeqDR): A global grass-roots consortium to facilitate deposition, curation, annotation, and integrated analysis of genomic data for the mitochondrial disease clinical and research communities. Mol. Genet. Metab. 114, 388-396 (2015) [published online 2014]





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Freischmidt, A., Wieland, T. , Richter, B., Ruf, W., Schäffer, V., Müller, K., Marroquin, N., Nordin, F., Hübers, A., Weydt, P., Pinto, S., Press, R., Millecamps, S., Molko, N., Bernard, E., Desnuelle, C., Soriani, M.H., Dorst, J., Graf, E. , Nordström, U., Feiler, M.S., Putz, S., Böckers, T.M., Meyer, T., Winkler, A.S., Winkelmann, J., de Carvalho, M., Thal, D.R., Otto, M., Brännström, T., Volk, A.E., Kursula, P., Danzer, K.M., Lichtner, P. , Dikic, I., Meitinger, T. , Ludolph, A.C., Strom, T.-M. , Andersen, P.M.°, Weishaupt, J.H.°: Haploinsufficiency of TBK1 causes familial ALS and fronto-temporal dementia. Nat. Neurosci. 18, 631-636 (2015)

Grassmann, F., Friedrich, U., Fauser, S., Schick, T., Milenkovic, A., Schulz, H.L., von Strachwitz, C.N., Bettecken, T., Lichtner, P. , Meitinger, T. , Arend, N., Wolf, A., Haritoglou, C., Rudolph, G., Chakravarthy, U., Silvestri, G., Mckay, G.J., Freitag-Wolf, S., Krawczak, M., Smith, R., Merriam, J.C., Merriam, J.E., Allikmets, R.L., Heid, I.M., Weber, B.H.F.°: A candidate gene association study identifies DAPL1 as a female-specific susceptibility locus for Age-related Macular Degeneration (AMD). Neuromol. Med. 17, 111-120 (2015)

Hadchouel, A.#, Wieland, T. #, Griese, M.E.#, Baruffini, E.#, Lorenz-Depiereux, B. , Enaud, L., Graf, E. , Dubus, J.C., Halioui-Louhaïchi, S., Coulomb, A., Delacourt, C., Eckstein, G.N. , Zarbock, R., Schwarzmayr, T., Cartault, F., Meitinger, T. , Lodi, T., de Blic, J., Strom, T.-M. °: Biallelic mutations of methionyl-tRNA synthetase cause a specific type of pulmonary alveolar proteinosis prevalent on Réunion Island. Am. J. Hum. Genet. 96, 826-831 (2015)

Holzerova, E. , Prokisch, H. °: Mitochondria: Much ado about nothing? How dangerous is reactive oxygen species production? Int. J. Biochem. Cell Biol. 63, 16-20 (2015)


Huemer, M.°, Karall, D., Schossig, A., Abdenur, J.E., Al Jasmi, F., Biagosch, C.A., Distelmaier, F., Freisinger, P., Graham, B.H., Haack, T.B. , Hauser, N., Hertecant, J., Ebrahimi-Fakhari, D., Konstantopoulou, V., Leydiker, K., Lourenco, C.M., Scholl-Bürgi, S., Wilichowski, E., Wolf, N.I., Wortmann, S.B., Taylor, R.W., Mayr, J.A., Bonnen, P.E., Sperl, W., Prokisch, H. , McFarland, R.: Clinical, morphological, biochemical, imaging and outcome parameters in 21 individuals with mitochondrial maintenance defect related to FBXL4 mutations. J. Inherit. Metab. Dis., DOI: 10.1007/s10545-015-9836-6 (2015)



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Koch, J., Freisinger, P., Feichtinger, R.G., Zimmermann, F.A., Rauscher, C., Wagentristl, H.P., Konstantopoulou, V., Seidl, R., Haack, T.B. , Prokisch, H. , Ahting, U., Sperl, W., Mayr, J.A., Maier, E.M.°: Mutations in TTC19: Expanding the molecular, clinical and biochemical phenotype. Orphanet J. Rare Dis. 10:40 (2015)

Kolder, I.C., Tanck, M.W., Postema, P.G., Barc, J., Sinner, M.F., Zumhagen, S., Husemann, A., Stallmeyer, B., Koopmann, T.T., Hofman, N., Pfeufer, A. , Lichtner, P. , Meitinger, T. , Beckmann, B.M., Myerburg, R.J., Bishopric, N.H., Roden, D.M., Kääb, S., Wilde, A.A., Schott, J.J., Schulze-Bahr, E., Bezzina, C.R.°: Analysis for genetic modifiers of disease severity in patients with long QT syndrome type 2. Circ. Cardiovasc. Genet., DOI: 10.1161/CIRCGENETICS.114.000785 (2015)


Lichtenauer, U.D.°, di Dalmazi, G., Slater, E.P., Wieland, T. , Kuebart, A., Schmittfull, A. , Schwarzmayr, T. , Diener, S. , Wiese, D., Thasler, W.E., Reincke, M., Meitinger, T. , Schott, M., Fassnacht, M., Bartsch, D.K., Strom, T.-M. , Beuschlein, F.: Frequency and clinical correlates of somatic Ying Yang 1 mutations in sporadic insulinomas. J. Clin. Endocrinol. Metab., DOI: 10.1210/jc.2015-1100 (2015)


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Mayr, J.A.°, Haack, T.B. , Freisinger, P., Karall, D., Makowski, C.C., Koch, J., Feichtinger, R.G., Zimmermann, F.A., Rolinski, B., Ahting, U., Meitinger, T. , Prokisch, H. , Sperl, W.J.K.: Spectrum of combined respiratory chain defects. J. Inherit. Metab. Dis., DOI: 10.1007/s10545-015-9831-y (2015)


Nalls, M.A.°, Saad, M., Noyce, A.J., Keller, M.F., Schrag, A., Bestwick, J.P., Traynor, B.J., Gibbs, J.R., Hernandez, D.G., Cookson, M.R., Morris, H.R., Williams, N., Gasser, T., Heutink, P., Wood, N., Hardy, J., Martinez, M., Singleton, A.B., International Parkinson's Disease Genomics Consortium (IPDGC) (Illig, T. , Lichtner, P. ), Wellcome Trust Case Control Consortium 2 (WTCCC2), North American Brain Expression Consortium, United Kingdom Brain Expression Consortium (UKBEC): Genetic comorbidities in Parkinson's disease. Hum. Mol. Genet. 23, 831-841 (2014)


Poos, K.#, Smida, J. #, Maugg, D. , Eckstein, G.N. , Baumhoer, D. , Nathrath, M. , Korsching, E.°: Genomic heterogeneity of osteosarcoma - shift from single candidates to functional modules. PLoS ONE 10:e0123082 (2015)

Porta, A.°, Girardengo, G., Bari, V., George, A.L. Jr., Brink, P.A., Goosen, A., Crotti, L. , Schwartz, P.J.: Autonomic control of heart rate and QT interval variability influences arrhythmic risk in long QT syndrome type 1. J. Am. Coll. Cardiol. 65, 367-374 (2015)

Schiff, M.°, Haberberger, B. , Xia, C.P., Mohsen, A.W., Goetzman, E.S., Wang, Y., Uppala, R., Zhang, Y., Karunanidhi, A., Prabhu, D., Alharbi, H., Prochownik, E.V., Haack, T.B. , Häberle, J., Munnich, A., Rotig, A., Taylor, R.W., Nicholls, R.D., Kim, J.J., Prokisch, H. , Vockley, J.°: Complex I assembly function and fatty acid oxidation enzyme activity of ACAD9 both contribute to disease severity in ACAD9 deficiency. Hum. Mol. Genet. 24, 3238-3247 (2015)

Schulte, E.C. , Fukumori, A., Mollenhauer, B., Hor, H., Arzberger, T., Perneczky, R., Kurz, A., Diehl-Schmid, J., Hüll, M., Lichtner, P. , Eckstein, G.N. , Zimprich, A., Haubenberger, D., Pirker, W., Brücke, T., Bereznai, B., Molnar, M.J., Lorenzo-Betancor, O., Pastor, P., Peters, A. , Gieger, C. , Estivill, X., Meitinger, T. , Kretzschmar, H.A., Trenkwalder, C., Haass, C., Winkelmann, J. °: Rare variants in β-Amyloid Precursor Protein (APP) and Parkinson's disease. Eur. J. Hum. Genet., DOI: 10.1038/ejhg.2014.300 (2015)


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Sperl, W.J.K.°, Fleuren, L., Freisinger, P., Haack, T.B. , Ribes, A.A., Feichtinger, R.G., Rodenburg, R.J.T., Zimmermann, F.A., Koch, J., Rivera, I.A., Prokisch, H. , Smeitink, J.A.M., Mayr, J.A.: The spectrum of pyruvate oxidation defects in the diagnosis of mitochondrial disorders. J. Inherit. Metab. Dis., DOI: 10.1007/s10545-014-9787-3 (2015)

Steichen-Gersdorf, E.°, Lorenz-Depiereux, B. , Strom, T.-M. , Shaw, N.J.: Early onset hearing loss in autosomal recessive hypophosphatemic rickets caused by loss of function mutation in ENPP1. J. Pediatr. Endocrinol. Metab., DOI: 10.1515/jpem-2014-0531 (2015)

Stitziel, N.O., Won, H., Morrison, A.C., Peloso, G.M., Do, R., Lange, L.A., Fontanillas, P., Gupta, N., Duga, S., Goel, A.K., Farrall, M.J., Saleheen, D., Ferrario, P., König, I.R., Asselta, R., Merlini, P.A., Marziliano, N., Notarangelo, M.F., Schick, U.M., Auer, P.L., Assimes, T.L., Reilly, M.P., Wilensky, R.L., Rader, D.J., Kees Hovingh, G., Meitinger, T. , Kessler, T., Kastrati, A., Laugwitz, K.L., Siscovick, D.S., Rotter, J.I., Hazen, S.L., Tracy, R.P., Cresci, S.G., Spertus, J.A., Jackson, R.D., Schwartz, S.M., Natarajan, P., Crosby, J.R., Muzny, D.M., Ballantyne, C.M., Rich, S.S., O'Donnell, C.J., Abecasis, G.R., Sunyaev, S.R., Nickerson, D.A., Buring, J.E., Ridker, P.M., Chasman, D.I., Austin, E., Ye, Z., Kullo, I.J., Weeke, P.E., Shaffer, C.M., Bastarache, L.A., Denny, J.C., Roden, D.M.L., Palmer, C.N.A., Deloukas, P., Lin, D., Tang, Z., Erdmann, J., Schunkert, H., Danesh, J., Marrugat, J., Elosua, R., Ardissino, D., McPherson, R.M., Watkins, H., Reiner, A.P., Wilson, J.G., Altshuler, D.M., Gibbs, R.A.L., Lander, E.S., Boerwinkle, E.E., Gabriel, S.B., Kathiresan, S.°: Inactivating mutations in NPC1L1 and protection from coronary heart disease. N. Engl. J. Med. 371, 2072-2082 (2014)



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Weinmaier, T.#, Hoser, J.D.S.#, Eck, S., Kaufhold, I., Shima, K., Strom, T.-M. , Rattei, T., Rupp, J.°: Genomic factors related to tissue tropism in Chlamydia pneumoniae infection. BMC Genomics 16:268 (2015)


Williams, K.M., Verhoeven, V.J., Cumberland, P.M., Bertelsen, G., Wolfram, C., Buitendijk, G.H., Hofman, A., van Duijn, C.M., Vingerling, J.R., Kuijpers, R.W., Höhn, R., Mirshahi, A., Khawaja, A.P., Luben, R.N., Erke, M.G., von Hanno, T., Mahroo, O., Hogg, R., Gieger, C. , Cougnard-Grégoire, A., Anastasopoulos, E., Bron, A., Dartigues, J.F., Korobelnik, J.F., Creuzot-Garcher, C., Topouzis, F., Delcourt, C., Rahi, J.S., Meitinger, T., Fletcher, A., Foster, P.J., Pfeiffer, N., Klaver, C.C., Hammond, C.J.°: Prevalence of refractive error in Europe: The European Eye Epidemiology (E3) consortium. Eur. J. Epidemiol. 30, 305-315 (2015)

Wortmann, S.B.°, Zietkiewicz, S., Kousi, M., Szklarczyk, R., Haack, T.B. , Gersting, S.W., Muntau, A.C., Rakovic, A., Renkema, G.H., Rodenburg, R.J., Strom, T.-M. , Meitinger, T. , Rubio-Gozalbo, M.E., Chrusciel, E., Distelmaier, F., Golzio, C., Jansen, J.H., van Karnebeek, C., Lillquist, Y., Lücke, T., Ounap, K., Zordania, R., Yaplito-Lee, J., van Bokhoven, H., Spelbrink, J.N., Vaz, F.M., Pras-Raves, M., Ploski, R., Pronicka, E., Klein, C., Willemsen, M.A., de Brouwer, A.P., Prokisch, H. , Katsanis, N., Wevers, R.A.: CLPB mutations cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder. Am. J. Hum. Genet. 96, 245-257 (2015)


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Combs, S.E.°, Engelhard, C., Kopp, C., Wiedenmann, N. , Schramm, O. , Prokic, V., Debus, J. , Molls, M., Grosu, A.L.: Long-term outcome after highly advanced single-dose or fractionated radiotherapy in patients with vestibular schwannomas - pooled results from 3 large German centers. Radiother. Oncol. 114, 378-383 (2015)

Schilling, D. , Kühnel, A., Tetzlaff, F., Konrad, S., Multhoff, G. °: NZ28-induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Cancer Immunol. Immunother. 64, 599-608 (2015)

Specht, H.M., Ahrens, N., Blankenstein, C., Duell, T.H.G., Fietkau, R.J., Gaipl, U.S., Günther, C., Gunther, S., Habl, G., Hautmann, H., Hautmann, M.G., Huber, R.M., Molls, M.M., Offner, R., Rödel, C.M., Rödel, F., Schuetz, M., Combs, S.E., Multhoff, G. °: Heat shock protein 70 (Hsp70) peptide activated Natural Killer (NK) cells for the treatment of patients with Non-Small Cell Lung Cancer (NSCLC) after radiochemotherapy (RCTx) - from preclinical studies to a clinical phase II trial. Front. Immunol. 6:162 (2015)


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Amaral, A.F.°, Minelli, C., Guerra, S., Wjst, M. , Probst-Hensch, N., Pin, I., Svanes, C., Janson, C., Heinrich, J., Jarvis, D.L.: The locus C11orf30 increases susceptibility to poly-sensitization. Allergy 70, 328–333 (2015) [published online 2014]

Conde, J.#, Tian, F. #, Hernandez, Y., Bao, C., Baptista, P.V., Cui, D., Stöger, T. °, de la Fuente, J.M.°: RNAi-based glyconanoparticles trigger apoptotic pathways for in vitro and in vivo enhanced cancer-cell killing. Nanoscale 7, 9083-9091 (2015)

Dau, T., Sarker, R.S. , Yildirim, A.Ö. , Eickelberg, O. , Jenne, D. °: Autoprocessing of neutrophil elastase near its active site reduces the efficiency of natural and synthetic elastase inhibitors. Nat. Commun. 6:6722 (2015)


Hellbach, K., Yaroshenko, A., Meinel, F.G., Yildirim, A.Ö. , Conlon, T.M. , Bech, M., Mueller, M., Velroyen, A., Notohamiprodjo, M., Bamberg, F., Auweter, S., Reiser, M., Eickelberg, O. , Pfeiffer, F.°: In vivo dark-field radiography for early diagnosis and staging of pulmonary emphysema. Invest. Radiol., DOI: 10.1097/RLI.0000000000000147 (2015)


Marcos, V., Zhou-Suckow, Z., Yildirim, A.Ö. , Bohla, A. , Hector, A., Vitkov, L., Krautgartner, W.D., Stoiber, W., Griese, M., Eickelberg, O. , Mall, M.A., Hartl, D.°: Free DNA in cystic fibrosis airway fluids correlates with airflow obstruction. Mediators Inflamm. 2015:408935 (2015)

Meiners, S. °, Eickelberg, O. , Königshoff, M. : Hallmarks of the ageing lung. Eur. Respir. J. 45, 807-827 (2015)

Sarker, R.S. , John-Schuster, G. , Bohla, A. , Mutze, K. , Burgstaller, G. , Bedford, M.T., Königshoff, M. , Eickelberg, O. , Yildirim, A.Ö. °: CARM1 regulates alveolar epithelial senescence and elastase-induced emphysema susceptibility. Am. J. Respir. Cell Mol. Biol., DOI: 10.1165/rcmb.2014-0216OC (2015)

Schamberger, A.C. , Staab-Weijnitz, C.A. , Mise-Racek, N. , Eickelberg, O. °: Cigarette smoke alters primary human bronchial epithelial cell differentiation at the air-liquid interface. Sci. Rep. 5:8163 (2015)


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Thannickal, V.J., Murthy, M., Balch, W.E., Chandel, N.S., Meiners, S. , Eickelberg, O. , Selman, M., Pardo, A., White, E.S., Levy, B.D., Busse, P.J., Tuder, R.M., Antony, V.B., Sznajder, J.I., Budinger, G.R.°: Blue journal conference : Aging and susceptibility to lung disease. Am. J. Respir. Crit. Care Med. 191, 261-269 (2015)

Uhl, F. , Vierkotten, S. , Wagner, D. , Burgstaller, G. , Costa, R. , Koch, I., Lindner, M., Meiners, S. , Eickelberg, O. , Königshoff, M. °: Preclinical validation and imaging of Wnt-induced repair in human 3D lung tissue cultures. Eur. Respir. J., DOI: 10.1183/09031936.00183214 (2015)

van Rijt, S.H. °, Bölükbas, D.A., Argyo, C., Datz, S., Lindner, M. , Eickelberg, O. , Königshoff, M. , Bein, T., Meiners, S. : Protease-mediated release of chemotherapeutics from mesoporous silica nanoparticles to ex vivo human and mouse lung tumors. ACS Nano 9, 2377-2389 (2015)

Vock, C., Yildirim, A.Ö. , Wagner, C., Schlick, S., Lunding, L.P., Lee, C.G., Elias, J.A., Fehrenbach, H., Wegmann, M.°: Distal airways are protected from goblet cell metaplasia by diminished expression of IL-13 signaling components. Clin. Exp. Allergy, DOI: 10.1111/cea.12526 (2015)


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Bauer, C., Gobel, K., Nagaraj, N., Colantuoni, C., Wang, M., Müller, U., Kremmer, E. , Rottach, A., Leonhardt, H.°: Phosphorylation of TET proteins is regulated via O-GlcNAcylation by the glycosyltransferase OGT. J. Biol. Chem. 290, 4801-4812 (2015)

Bauer, C.°, Hees, C., Sterzik, A., Bauernfeind, F., Mak'Anyengo, R., Duewell, P., Lehr, H.A., Nößner, E. , Wank, R., Trauzold, A., Endres, S., Dauer, M., Schnurr, M.: Proapoptotic and antiapoptotic proteins of the Bcl-2 family regulate sensitivity of pancreatic cancer cells toward gemcitabine and T-cell-mediated cytotoxicity. J. Immunother. 38, 116-126 (2015)

Beer, A.J.°, Pelisek, J., Heider, P., Saraste, A., Reeps, C., Metz, S., Seidl, S. , Kessler, H., Wester, H.-J., Eckstein, H.H., Schwaiger, M.: PET/CT imaging of integrin αvβ3 expression in human carotid atherosclerosis. JACC-Cardiovasc. Imag. 7, 178-187 (2014)

Dorn, T., Goedel, A., Lam, J.T., Haas, J.A., Tian, Q., Herrmann, F., Bundschu, K., Dobreva, G., Schiemann, M., Dirschinger, R.J., Guo, Y., Kühl, S.J., Sinnecker, D., Lipp, P., Laugwitz, K.L., Kühl, M., Moretti, A.°: Direct Nkx2-5 transcriptional repression of Isl1 controls cardiomyocyte subtype identity. Stem Cells 33, 1113-1129 (2015)

Haase, K., Raffegerst, S.H. , Schendel, D.J. , Frishman, D. °: Expitope: A web server for epitope expression. Bioinformatics, DOI: 10.1093/bioinformatics/btv068 (2015)

Haftmann, C., Stittrich, A.B., Zimmermann, J., Fang, Z., Hradilkova, K., Bardua, M., Westendorf, K., Heinz, G.A., Riedel, R., Siede, J., Lehmann, K., Weinberger, E.E., Zimmel, D., Lauer, U.M., Häupl, T., Sieper, J., Backhaus, M., Neumann, C., Hoffmann, U., Porstner, M., Chen, W., Grün, J.R., Baumgrass, R., Matz, M., Löhning, M., Scheffold, A., Wittmann, J., Chang, H., Rajewsky, N., Jack, H.M., Radbruch, A.H., Mashreghi, M.F.°: MiR-148a is upregulated by Twist1 and T-bet and promotes Th1-cell survival by regulating the proapoptotic gene Bim. Eur. J. Immunol. 45, 1192-1205 (2015)

Kellner, M. , Rohrmoser, M. , Forne, I., Voss, K. , Burger, K. , Mühl, B. , Gruber-Eber, A. , Kremmer, E. , Imhof, A., Eick, D. °: DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex. Exp. Cell Res., DOI: 10.1016/j.yexcr.2015.03.017 (2015)



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Lahm, H.°, Doppler, S.A., Dressen, M., Werner, A., Adamczyk, K., Schrambke, D., Brade, T., Laugwitz, K.L., Deutsch, M.A., Schiemann, M. , Lange, R., Moretti, A., Krane, M.: Live fluorescent RNA-based detection of pluripotency gene expression in embryonic and induced pluripotent stem cells of different species. Stem Cells 33, 392-402 (2015)

Linzen, U., Lilischkis, R., Pandithage, R., Schilling, B., Ullius, A., Luscher-Firzlaff, J., Kremmer, E. , Lüscher, B.°, Vervoorts, J.°: ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53. PLoS ONE 10:e0123736 (2015)

Loffredo-Verde, E., Abdel-Aziz, I.Z., Albrecht, J. , El Guindy, N.M., Yacob, M., Solieman, A.S., Protzer, U. , Busch, D.H. , Layland, L.E., Prazeres da Costa, C.U.: Schistosome infection aggravates HCV-related liver disease and induces changes in the regulatory T-cell phenotype. Parasite Immunol. 37, 97-104 (2015)

Lorenz, F.K., Wilde, S. , Voigt, K., Kieback, E., Mosetter, B. , Schendel, D.J. , Uckert, W.°: Codon optimization of the human papillomavirus E7 oncogene induces a CD8+ T cell response to a cryptic epitope not harbored by wild-type E7. PLoS ONE 10:e0121633 (2015)

Martinez, G.J., Pereira, R.M., Äijö, T., Kim, E.Y., Marangoni, F., Pipkin, M.E., Togher, S., Heissmeyer, V. , Zhang, Y.C., Crotty, S., Lamperti, E.D., Ansel, K.M., Mempel, T.R., Lähdesmäki, H., Hogan, P.G., Rao, A.°: The transcription factor NFAT promotes exhaustion of activated CD8+ T Cells. Immunity 42, 265–278 (2015)

Schuster, F.R.#, Stanglmaier, M.#, Woessmann, W., Winkler, B., Siepermann, M., Meisel, R., Schlegel, P.G., Hess, J., Lindhofer, H.G., Borkhardt, A., Buhmann, R. °: Immunotherapy with the trifunctional anti-CD20 x anti-CD3 antibody FBTA05 (Lymphomun) in paediatric high-risk patients with recurrent CD20-positive B cell malignancies. Br. J. Haematol. 169, 90-102 (2015) [published online 2014]

Seifert, R.#, Flick, M.#, Bönigk, W., Alvarez, L., Trötschel, C., Poetsch, A., Müller, A., Goodwin, N., Pelzer, P., Kashikar, N.D., Kremmer, E. , Jikeli, J., Timmermann, B., Kuhl, H., Fridman, D., Windler, F., Kaupp, U.B.°, Strünker, T.°: The CatSper channel controls chemosensation in sea urchin sperm. EMBO J. 34, 379-392 (2015) [published online 2014]

Serth, K., Schuster-Gossler, K., Kremmer, E. , Hansen, B.T., Marohn-Köhn, B., Gossler, A.°: O-fucosylation of DLL3 is required for its function during somitogenesis. PLoS ONE 10:e0123776 (2015)

Solchenberger, B., Russell, C., Kremmer, E. , Haass, C., Schmid, B.°: Granulin knock out zebrafish lack frontotemporal lobar degeneration and neuronal ceroid lipofuscinosis pathology. PLoS ONE 10:e0118956 (2015)

Srivastava, M., Duan, G., Kershaw, N.J., Athanasopoulos, V., Yeo, J.H., Ose, T., Hu, D., Brown, S.H., Jergic, S., Patel, H.R., Pratama, A., Richards, S., Verma, A., Jones, E.Y., Heissmeyer, V. , Preiss, T., Dixon, N.E., Chong, M.M., Babon, J.J., Vinuesa, C.G.°: Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis. Nat. Commun. 6:6253 (2015)


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Strube, C.°, Haake, C., Sager, H., Schorderet Weber, S., Kaminsky, R., Buschbaum, S., Joekel, D., Schicht, S., Kremmer, E. , Korrell, J., Schnieder, T., von Samson-Himmelstjerna, G.: Vaccination with recombinant paramyosin against the bovine lungworm Dictyocaulus viviparus considerably reduces worm burden and larvae shedding. Parasit. Vectors 8:119 (2015)

Vick, B. , Rothenberg, M., Sandhöfer, N. , Carlet, M. , Finkenzeller, C. , Krupka, C. , Grunert, M. , Trumpp, A., Corbacioglu, S., Ebinger, M., Andre, M.C., Hiddemann, W. , Schneider, S., Subklewe, M. , Metzeler, K.H., Spiekermann, K. , Jeremias, I. °: An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging. PLoS ONE 10:e0120925 (2015)

Warth, S.C. , Höfig, K.P. , Hiekel, A. , Schallenberg, S., Jovanovic, K., Klein, L., Kretschmer, K., Ansel, K.M., Heissmeyer, V. °: Induced miR-99a expression represses Mtor cooperatively with miR-150 to promote regulatory T-cell differentiation. EMBO J. 34, 1195-1213 (2015)


Zhao, Y.°, Zhao, L., Ischenko, I., Bao, Q., Schwarz, B.E., Nieß, H., Wang, Y., Renner, A., Mysliwietz, J. , Jauch, K.-W., Nelson, P.J., Ellwart, J.W. , Bruns, C.J., Camaj, P.°: Antisense inhibition of microRNA-21 and microRNA-221 in tumor-initiating stem-like cells modulates tumorigenesis, metastasis, and chemotherapy resistance in pancreatic cancer. Target. Oncol., DOI: 10.1007/s11523-015-0360-2 (2015)

Zugmaier, G., Klinger, M.°, Schmidt, M., Subklewe, M. : Clinical overview of anti-CD19 BiTE® and ex vivo data from anti-CD33 BiTE® as examples for retargeting T cells in hematologic malignancies. Mol. Immunol., DOI: 10.1016/j.molimm.2015.02.033 (2015)


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Eitelhuber, A.C. , Vosyka, O., Nagel, D. , Bognar, M. , Lenze, D., Lammens, K., Schlauderer, F., Hlahla, D. , Hopfner, K.P., Lenz, G., Hummel, M., Verhelst, S.H., Krappmann, D. °: Activity-based probes for detection of active MALT1 paracaspase in immune cells and lymphomas. Chem. Biol. 22, 129-138 (2014)

Filser, J.G. °, Artati, A. , Li, Q. , Pütz, C. , Semder, B. , Klein, D. , Kessler, W. : Novel and existing data for a future physiological toxicokinetic model of ethylene and its metabolite ethylene oxide in mouse, rat and human. Chem. Biol. Interact., DOI: 10.1016/j.cbi.2015.04.002 (2015)

Nagel, D. , Krappmann, D. °: Detection of recombinant and cellular MALT1 paracaspase activity. Methods Mol. Biol. 1280, 239-246 (2015)


Schulz, S. , Lichtmannegger, J. , Schmitt, S. , Leitzinger, C. , Eberhagen, C. , Einer, C. , Kerth, J. , Aichler, M., Zischka, H. °: A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and brain. Methods Mol. Biol. 1295, 75-86 (2015)

Vincendeau, M. , Krappmann, D. , Hadian, K. °: In vitro detection of NEMO-ubiquitin binding using DELFIA and microscale thermophoresis assays. Methods Mol. Biol. 1280, 311-320 (2015)

Vincendeau, M. , Göttesdorfer, I. , Schreml, J., Wetie, A. , Mayer, J., Greenwood, A.D., Helfer, M. , Kramer, S., Seifarth, W., Hadian, K. , Brack-Werner, R. , Leib-Mösch, C. °: Modulation of Human Endogenous Retrovirus (HERV) transcription during persistent and de novo HIV-1 infection. Retrovirol. 12:27 (2015)

Wiebel, F.J. °: Chemistry and primary toxicity of tobacco and tobacco smoke. Prog. Respir. Res. 42, 37-46 (2015)


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Aichler, M. , Walch, A.K. °: MALDI Imaging mass spectrometry: Current frontiers and perspectives in pathology research and practice. Lab. Invest. 95, 422-431 (2015)

Aichler, M. , Huber, K. , Schilling, F., Lohöfer, F., Kosanke, K., Meier, R., Rummeny, E.J., Walch, A.K. °, Wildgruber, M.: Spatially resolved quantification of Gadolinium(III)-based magnetic resonance agents in tissue by MALDI imaging mass spectrometry after in vivo MRI. Angew. Chem.-Int. Edit. 54, 4279-4283 (2015)

Almstätter, I., Mykhaylyk, O., Settles, M., Altomonte, J., Aichler, M. , Walch, A.K. , Rummeny, E.J., Ebert, O., Plank, C., Braren, R.°: Characterization of magnetic viral complexes for targeted delivery in oncology. Theranostics 5, 667-685 (2015)


Bauer, L., Takacs, A., Slotta-Huspenina, J., Langer, R., Becker, K., Novotny, A., Ott, K., Walch, A.K. , Hapfelmeier, A., Keller, G.°: Clinical significance of NOTCH1 and NOTCH2 expression in gastric carcinomas: An immunohistochemical study. Front. Oncol. 5:94 (2015)


Beckers, A.#°, Lodish, M.#, Giampaolo, T., Rostomyan, L., Lee, M.S., Faucz, F.R., Yuan, B., Choong, C., Caberg, J.H., Verrua, E., Naves, L.A., Cheetham, T., Young, J., Lysy, P., Petrossians, P., Cotterill, A., Shah, N., Metzger, D., Castermans, E., Ambrosio, M.R., Villa, C., Strebkova, N., Mazerkina, N., Gaillard, S., Barcelos Barra, G., Casulari, L.A., Neggers, S., Salvatori, R., Jaffrain-Rea, M.L., Zacharin, M., Lecumberri Santamaria, B., Zacharieva, S., Lim, E.M., Mantovani, G., Zatelli, M.C., Collins, M.T., Bonneville, J.F., Quezado, M.M., Chittiboina, P., Oldfield, E., Bours, V., Liu, P., de Herder, W.W., Pellegata, N.S. , Lupski, J.R., Daly, A.F., Stratakis, C.A.: X-Linked Acrogigantism (X-LAG) syndrome: Clinical profile and therapeutic responses. Endocr.-Relat. Cancer, DOI: 10.1530/ERC-15-0038 (2015)

Buck, A. #, Ly, A. #, Balluff, B., Sun, N. , Gorzolka, K. , Feuchtinger, A. , Janssen, K.P., Kuppen, P.J., van de Velde, C.J., Weirich, G., Erlmeier, F., Langer, R., Aubele, M. , Zitzelsberger, H. , Aichler, M. , Walch, A.K. °: High-resolution MALDI-FT-ICR MS imaging for the analysis of metabolites from formalin-fixed paraffin-embedded clinical tissue samples. J. Pathol., DOI: 10.1002/path.4560 (2015)


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Erlmeier, F., Feuchtinger, A. , Borgmann, D.M. , Rudelius, M., Autenrieth, M., Walch, A.K. , Weirich, G.°: Supremacy of modern morphometry in typing renal oncocytoma and malignant look-alikes. Histochem. Cell Biol., DOI: 10.1007/s00418-015-1324-4 (2015)

Falkenberg, N. °, Anastasov, N. , Schaub, A. , Radulovic, V. , Schmitt, M., Magdolen, V., Aubele, M. : Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221. Oncotarget 6, 8103-8114 (2015)

Genitsch, V., Novotny, A., Seiler, C.A., Kröll, D., Walch, A.K. , Langer, R.°: Epstein-Barr virus in gastro-esophageal adenocarcinomas - single center experiences in the context of current literature. Front. Oncol. 5:73 (2015)


Ingold, I. , Aichler, M. , Yefremova, E. , Roveri, A., Buday, K. , Doll, S. , Tasdemir, A. , Hoffard, N. , Wurst, W., Walch, A.K. , Ursini, F., Friedmann Angeli, J.P. , Conrad, M. °: Expression of a catalytically inactive mutant form of Glutathione peroxidase 4 (Gpx4) confers a dominant-negative effect in male fertility. J. Biol. Chem., DOI: 10.1074/jbc.M115.656363 (2015)


Lee, M.S., Wiedemann, T. , Gross, C., Leinhäuser, I. , Roncaroli, F., Braren, R., Pellegata, N.S. °: Targeting PI3K/mTOR signaling displays potent antitumor efficacy against nonfunctioning pituitary adenomas. Clin. Cancer Res., DOI: 10.1158/1078-0432.CCR-15-0288 (2015)


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Miras, A., Mogford, J.T., Wright, J.E.°, Mendoza, N.N., Xekouki, P., Lakhani, A., Pellegata, N.S. , Stratakis, C.A., Roncaroli, F., Russell-Jones, D.L.: Ovarian hyperstimulation from ectopic hypersecretion of follicle stimulating hormone. Lancet 385, 392 (2015)

Poos, K.#, Smida, J. #, Maugg, D. , Eckstein, G.N. , Baumhoer, D. , Nathrath, M. , Korsching, E.°: Genomic heterogeneity of osteosarcoma - shift from single candidates to functional modules. PLoS ONE 10:e0123082 (2015)

Ribi, S.#, Baumhoer, D. #, Lee, K.#, Edison, Teo, A.S., Madan, B., Zhang, K., Kohlmann, W.K., Yao, F., Lee, W.H., Hoi, Q., Cai, S.W., Woo, X.Y., Tan, P.L., Jundt, G., Smida, J. , Nathrath, M. , Sung, W.K., Schiffman, J.D., Virshup, D.M.°, Hillmer, A.M.°: TP53 intron 1 hotspot rearrangements are specific to sporadic osteosarcoma and can cause Li-Fraumeni syndrome. Oncotarget 6, 7727-7740 (2015)

Sambugaro, S., di Ruvo, M., Ambrosio, M.R., Pellegata, N.S. , Bellio, M., Guerra, A., Buratto, M., Foschini, M.P., Tagliati, F., degli Uberti, E.C., Zatelli, M.C.°: Early onset acromegaly associated with a novel deletion in CDKN1B 5'UTR region. Endocrine 49, 58-64 (2015)


Schulz, S. , Lichtmannegger, J. , Schmitt, S. , Leitzinger, C. , Eberhagen, C. , Einer, C. , Kerth, J. , Aichler, M., Zischka, H. °: A protocol for the parallel isolation of intact mitochondria from rat liver, kidney, heart, and brain. Methods Mol. Biol. 1295, 75-86 (2015)

Singh, S.K., Chen, N.M., Hessmann, E., Siveke, J., Lahmann, M., Singh, G., Voelker, N., Vogt, S., Esposito, I., Schmidt, A., Brendel, C., Stiewe, T., Gaedcke, J., Merenberger, M., Crawford, H.C., Bamlet, W.R., Zhang, J.S., Li, X.K., Smyrk, T.C., Billadeau, D.D., Hebrok, M., Neesse, A., Koenig, A., Ellenrieder, V.°: Antithetical NFATc1-Sox2 and p53-miR200 signaling networks govern pancreatic cancer cell plasticity. EMBO J. 34, 517-530 (2015)

Teiluf, K.#, Seidl, C.#, Blechert, B., Gaertner, F.C., Gilbertz, K.P., Fernandez, V., Bassermann, F., Endell, J., Boxhammer, R., Leclair, S., Vallon, M., Aichler, M. , Feuchtinger, A. , Bruchertseifer, F., Morgenstern, A., Essler, M.°: α-Radioimmunotherapy with 213Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma. Oncotarget 6, 4692-4703 (2015)

van Berkel, A., Upendrao, J., Lenders, J., Pellegata, N.S. , Kusters, B., Piscaer, I., Hermus, A.R., Plantinga, T.S., Langenhuijsen, H., Vriens, D., Janssen, M., Gotthardt, M., Timmers, H.°: Semi-quantitative 123I-metaiodobenzylguanidine scintigraphy to distinguish pheochromocytoma and paraganglioma from physiological adrenal uptake and its correlation with genotype-dependent expression of catecholamine transporters. J. Nucl. Med., DOI: 10.2967/jnumed.115.154815 (2015)

Velikova, V.B. , Müller, C. , Ghirardo, A. , Rock, T. , Aichler, M. , Walch, A.K. , Schmitt-Kopplin, P. , Schnitzler, J.-P. °: Knocking down of isoprene emission modifies the lipid matrix of thylakoid membranes and influences the chloroplast ultrastructure in poplar. Plant Physiol., DOI: 10.1104/pp.15.00612 (2015)


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Vukicevic, V., Rubin de Celis, M.F., Pellegata, N.S. , Bornstein, S.R., Androutsellis-Theotokis, A., Ehrhart-Bornstein, M.°: Adrenomedullary progenitor cells: Isolation and characterization of a multi-potent progenitor cell population. Mol. Cell. Endocrinol. 408, 178-184 (2015)

Wester, H.J.°, Keller, U., Schottelius, M., Beer, A., Philipp-Abbrederis, K., Hoffmann, F., Simecek, J., Gerngross, C., Lassmann, M., Herrmann, K., Pellegata, N.S. , Rudelius, M., Kessler, H., Schwaiger, M.: Disclosing the CXCR4 expression in lymphoproliferative diseases by targeted molecular imaging. Theranostics 5, 618-630 (2015)


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Azimzadeh, O. , Atkinson, M.J. , Tapio, S. °: Qualitative and quantitative proteomic analysis of Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Methods Mol. Biol. 1295, 109-115 (2015)

Barjaktarovic, Z. , Kempf, S.J. , Sriharshan, A. , Merl-Pham, J. , Atkinson, M.J. , Tapio, S. °: Ionizing radiation induces immediate protein acetylation changes in human cardiac microvascular endothelial cells. J. Radiat. Res., DOI: 10.1093/jrr/rrv014 (2015)

Falkenberg, N. °, Anastasov, N. , Schaub, A. , Radulovic, V. , Schmitt, M., Magdolen, V., Aubele, M. : Secreted uPAR isoform 2 (uPAR7b) is a novel direct target of miR-221. Oncotarget 6, 8103-8114 (2015)

Kempf, S.J. , Mörtl, S. , Sepe, S., von Toerne, C. , Hauck, S. , Atkinson, M.J. , Mastroberardino, P.G., Tapio, S.°: Low-dose ionizing radiation rapidly affects mitochondrial and synaptic signaling pathways in murine hippocampus and cortex. J. Proteome Res. 14, 2055-2064 (2015)

Kreuzer, M.°, Auvinen, A., Cardis, E., Hall, J., Jourdain, J.R., Laurier, D., Little, M.P., Peters, A. , Raj, K., Russell, N.S., Tapio, S. , Zhang, W., Gomolka, M.: Low-dose ionising radiation and cardiovascular diseases – strategies for molecular epidemiological studies in Europe. Mutat. Res.- Rev. Mutat. Res., DOI: 10.1016/j.mrrev.2015.03.002 (2015)

O'Leary, V.B. °, Ovsepian, S.V., Carrascosa, L.G., Buske, F.A., Radulovic, V. , Niyazi, M., Mörtl, S. , Trau, M., Atkinson, M.J. , Anastasov, N. : PARTICLE, a triplex-forming long ncRNA, regulates locus-specific methylation in response to low-dose irradiation. Cell Rep. 11, 474-485 (2015)

Ovsepian, S.V.°, Bodeker, M.O., O'Leary, V.B. , Lawrence, G.W., Dolly, J.O.: Internalization and retrograde axonal trafficking of tetanus toxin in motor neurons and trans-synaptic propagation at central synapses exceed those of its C-terminal-binding fragments. Brain Struct. Funct. 220, 1825-1838 (2015)

Salomaa, S.°, Averbeck, D., Ottolenghi, A., Sabatier, L., Bouffler, S., Atkinson, M.J. , Jourdain, J.R.: European low-dose radiation risk research strategy: Future of research on biological effects at low doses. Radiat. Prot. Dosim. 164, 38-41 (2015)

Skiöld, S., Azimzadeh, O. , Merl-Pham, J. , Näslund, I., Wersäll, P.J., Lidbrink, E.K., Tapio, S. , Harms-Ringdahl, M., Haghdoost, S.°: Unique proteomic signature for radiation sensitive patients: A comparative study between normo-sensitive and radiation sensitive breast cancer patients. Mutat. Res. -Fund. Mol. Mech. Mutag., DOI: 10.1016/j.mrfmmm.2014.12.002 (2015)

Summerer, I. , Niyazi, M., Unger, K. , Pitea, A. , Zangen, V. , Hess, J. , Atkinson, M.J. , Belka, C. , Mörtl, S. , Zitzelsberger, H. °: Erratum: Changes in circulating microRNAs after radiochemotherapy in head and neck cancer patients. Radiat. Oncol. 10:102 (2015)


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Aerts, A.M., Impens, N.R.E.N., Baatout, S.°, Benotmane, M.A., Camps, J., Dabin, J.M., Derradji, H., Grosche, B., Horemans, N., Jourdain, J.R., Moreels, M., Perko, T., Quintens, R., Repussard, J., Rühm, W. , Schneider, T., Struelens, L., Hardeman, F.: Joint research towards a better radiation protection : Highlights of the fifth MELODI workshop. J. Radiol. Prot. 34, 931-956 (2014)

Alloni, D.°, Baiocco, G., Babini, G., Friedland, W. , Kundrát, P. , Mariotti, L., Ottolenghi, A.: Energy dependence of the complexity of dna damage induced by carbon ions. Radiat. Prot. Dosim., DOI: 10.1093/rpd/ncv292 (2015)

Chege, M.W.°, Hashim, N.O., Merenga, A.S., Meisenberg, O. , Tschiersch, J. : Estimation of annual effective dose due to radon and thoron concentrations in mud dwellings of Mrima Hill, Kenya. Radiat. Prot. Dosim., DOI: 10.1093/rpd/ncv231 (2015)

Discher, M. °, Hiller, M. , Woda, C. : MCNP simulations of a glass display used in a mobile phone as an accident dosimeter. Radiat. Meas. 75, 21-28 (2015)

Eidemüller, M. °, Holmberg, E., Jacob, P. , Lundell, M., Karlsson, P.: Breast cancer risk and possible mechanisms of radiation-induced genomic instability in the Swedish hemangioma cohort after reanalyzed dosimetry. Mutat. Res. 775, 1-9 (2015)

Friedland, W. , Kundrát, P. °: Chromosome aberration model combining radiation tracks, chromatin structure, DSB repair and chromatin mobility. Radiat. Prot. Dosim., DOI: 10.1093/rpd/ncv174 (2015)

Friedland, W. °, Kundrát, P. , Schmitt, E. : Modelling proton bunches focussed to submicrometre scales: Low-let radiation damage in high-let-like spatial structure. Radiat. Prot. Dosim., DOI: 10.1093/rpd/ncv146 (2015)

Hain, K.°, Faestermann, T., Famulok, N., Fimiani, L., Gómez-Guzmán, J.M., Korschinek, G., Kortmann, F., Lierse, C., Ludwig, P., Shinonaga, T. : Analytical method for the determination of Np and Pu in sea water by AMS with respect to the Fukushima accident. Nucl. Instrum. Methods Phys. Res. Sect. B, DOI: 10.1016/j.nimb.2015.04.018 (2015)

Kundrát, P. °, Friedland, W. : Impact of intercellular induction of apoptosis on low-dose radiation carcinogenesis. Radiat. Prot. Dosim., DOI: 10.1093/rpd/ncv169 (2015)

Kundrát, P. °, Friedland, W. : Mechanistic modelling of radiation-induced bystander effects. Radiat. Prot. Dosim., DOI: 10.1093/rpd/ncv170 (2015)

Li, C.°, Hauck, B., Capello, K., Nogueira, P. , Lopez, M.A., Kramer, G.H.: Counting 241Am in the BfS human skull phantom on contact - evaluation in the human monitoring laboratory. Health Phys. 108, 380-382 (2015)

Meisenberg, O. °, Tschiersch, J. °: Test of methods for retrospective activity size distribution determination from filter samples. Radiat. Meas. 76, 29-35 (2015)


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Rühm, W. °, Fantuzzi, E., Harrison, R.M., Schuhmacher, H., Vanhavere, F., Alves, J., Bottollier Depois, J.F., Fattibene, P., Knezevic, Z., Lopez, M.A., Mayer, S., Miljanić, S., Neumaier, S., Olko, P., Stadtmann, H., Tanner, R., Woda, C. : Eurados strategic research agenda: Vision for dosimetry of ionising radiation. Radiat. Prot. Dosim., DOI: 10.1093/rpd/ncv018 (2015)

Sakoda, S. °, Meisenberg, O. , Tschiersch, J. : Behavior of radon progeny produced in a scintillation cell in the flow-through condition. Radiat. Meas. 77, 41-45 (2015)

Schmitt, E. °, Friedland, W. , Kundrát, P. , Dingfelder, M., Ottolenghi, A.: Cross-section scaling for track structure simulations of low-energy ions in liquid water. Radiat. Prot. Dosim., DOI: 10.1093/rpd/ncv302 (2015)

Simonetto, C. °, Schöllnberger, H. , Azizova, T.V., Grigoryeva, E.S., Pikulina, M.V., Eidemüller, M. : Cerebrovascular diseases in workers at Mayak PA: The difference in radiation risk between incidence and mortality. PLoS ONE 10:e0125904 (2015)

Wittmaack, K. °: Attenuation length in ion-induced kinetic electron emission: A key to an understanding of angular-dependent yields. Phys. Rev. B Condens. Matter 91:115434 (2015)


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Asseng, S.°, Ewert, F., Martre, P., Rötter, R.P., Lobell, D.B., Cammarano, D., Kimball, A., Ottmann, M.J., Wall, G.W., White, J.W., Reynolds, M.P., Aldermann, P.D., Prasad, P.V.V., Aggarwal, P.K., Anothai, J., Basso, B., Biernath, C.J. , Challinor, A.J., de Sanctis, G., Doltra, J., Fereres, E., Garcia-Vila, M., Gayler, S., Hoogenboom, G., Hunt, L.A., Izaurralde, R.C., Jabloun, M., Jones, C.D., Kersebaum, K.C., Koehler, A.-K., Müller, C., Naresh Kumar, S., Nendel, C., O'Leary, G., Olesen, J.E., Palosuo, T., Priesack, E. , Eyshi Rezaei, E., Ruane, A.C., Semenov, M.A., Shcherbak, I., Stöckle, C., Stratonovitch, P., Streck,T., Supit, I., Tao, F., Thorburn, P.J., Waha, K., Wang, E., Wallach, D., Wolf, J., Zhao, Z., Zhu, Y.: Rising temperatures reduce global wheat production. Nat. Clim. Chang. 5, 143-147 (2015)

Eibisch, N. , Schroll, R. °, Fuß, R.: Effect of pyrochar and hydrochar amendments on the mineralization of the herbicide isoproturon in an agricultural soil. Chemosphere, DOI: 10.1016/j.chemosphere.2014.11.074 (2014)

Martre, P.°, Wallach, D., Asseng, S., Ewert, F., Jones, J.W., Rötter, R.P., Boote, K.J., Ruane, A.C., Thorburn, P.J., Cammarano, D., Hatfield, J.L., Rosenzweig, C., Aggarwal, P.K., Angulo, C., Basso, B., Bertuzzi, P., Biernath, C.J. , Brisson, N., Challinor, A.J., Doltra, J., Gayler, S., Goldberg, R., Grant, R.F., Heng, L., Hooker, J., Hunt, L.A., Ingwersen, J., Izaurralde, R.C., Kersebaum, K.C., Müller, C., Kumar, S.N., Nendel, C., O'Leary, G., Olesen, J.E., Osborne, T.M., Palosuo, T., Priesack, E. , Ripoche, D., Semenov, M.A., Shcherbak, I., Steduto, P., Stöckle, C.O., Stratonovitch, P., Streck, T., Supit, I., Tao, F., Travasso, M., Waha, K., White, J.W., Wolf, J.: Multimodel ensembles of wheat growth: Many models are better than one. Glob. Change Biol. 21, 911-925 (2015)

Qu, W.°, Bogena, H.R., Huisman, J.A.H., Vanderborght, J.P., Schuh, M. , Priesack, E. , Vereecken, H.: Predicting subgrid variability of soil water content from basic soil information. Geophys. Res. Lett. 42, 789-796 (2015)

Steinauer, K.°, Tilman, D., Wragg, P.D., Cesarz, S., Cowles, J.M., Pritsch, K. , Reich, P.B., Weisser, W.W., Eisenhauer, N.: Plant diversity effects on soil microbial functions and enzymes are stronger than warming in a grassland experiment. Ecology 96, 99-112 (2015)

Vogel, C.°, Heister, K., Buegger, F. , Tanuwidjaja, I. , Haug, S., Schloter, M. , Kögel-Knabner, I.: Clay mineral composition modifies decomposition and sequestration of organic carbon and nitrogen in fine soil fractions. Biol. Fertil. Soils 51, 427-442 (2015)

Wortmann, S.B.°, Zietkiewicz, S., Kousi, M., Szklarczyk, R., Haack, T.B. , Gersting, S.W., Muntau, A.C., Rakovic, A., Renkema, G.H., Rodenburg, R.J., Strom, T.-M. , Meitinger, T. , Rubio-Gozalbo, M.E., Chrusciel, E., Distelmaier, F., Golzio, C., Jansen, J.H., van Karnebeek, C., Lillquist, Y., Lücke, T., Ounap, K., Zordania, R., Yaplito-Lee, J., van Bokhoven, H., Spelbrink, J.N., Vaz, F.M., Pras-Raves, M., Ploski, R., Pronicka, E., Klein, C., Willemsen, M.A., de Brouwer, A.P., Prokisch, H. , Katsanis, N., Wevers, R.A.: CLPB mutations cause 3-methylglutaconic aciduria, progressive brain atrophy, intellectual disability, congenital neutropenia, cataracts, movement disorder. Am. J. Hum. Genet. 96, 245-257 (2015)


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Bergami, M.°, Masserdotti, G. , Temprana, S.G., Motori, E., Eriksson, T.M., Göbel, J., Yang, S.M., Conzelmann, K.K., Schinder, A.F., Götz, M. , Berninger, B.: A critical period for experience-dependent remodeling of adult-born neuron connectivity. Neuron 85, 710-717 (2015)

Calzolari, F. , Michel, J. , Baumgart, E.V. , Theis, F.J. , Götz, M.°, Ninkovic, J. °: Fast clonal expansion and limited neural stem cell self-renewal in the adult subependymal zone. Nat. Neurosci. 18, 490-492 (2015)

Kovalchuk, Y., Homma, R., Liang, Y., Maslyukov, A., Hermes, M., Thestrup, T., Griesbeck, O., Ninkovic, J. , Cohen, L.B., Garaschuk, O.°: In vivo odourant response properties of migrating adult-born neurons in the mouse olfactory bulb. Nat. Commun. 6:6349 (2015)

Saunders, N.R., Dreifuss, J., Dziegielewska, K.M., Johansson, P.A. , Habgood, M.D., Møllgård, K., Bauer, H.: The rights and wrongs of blood-brain barrier permeability studies: A walk through 100 years of history. Front. Neurosci. 8:404 (2014)


Taverna, E., Götz, M.°, Huttner, A.B.: The cell biology of neurogenesis: Toward an understanding of the development and evolution of the neocortex. Annu. Rev. Cell Dev. Biol. 30, 465-502 (2014)

Uzbas, F. , May, I.D., Parisi, A.M., Thompson, S.K., Kaya, A., Perkins, A.D., Memili, E.°: Molecular physiognomies and applications of adipose-derived stem cells. Stem Cell Rev. Rep. 11, 298-308 (2014)

Zhang, Y. , Lin, S., Karakatsani, A., Rüegg, M.A., Kröger, S.°: Differential regulation of AChR clustering in the polar and equatorial region of murine muscle spindles. Eur. J. Neurosci. 41, 69-78 (2015)

Zhang, Y. , Wesolowski, M., Karakatsani, A., Witzemann, V., Kröger, S.: Formation of cholinergic synapse-like specializations at developing murine muscle spindles. Dev. Biol. 393, 227-235 (2014)


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Anosova, I. , Melnik, S., Tripsianes, K. , Kateb, F. , Grummt, I., Sattler, M. °: A novel RNA binding surface of the TAM domain of TIP5/BAZ2A mediates epigenetic regulation of rRNA genes. Nucleic Acids Res., DOI: 10.1093/nar/gkv365 (2015)

Asami, S., Porter, J.R., Lange, O.F., Reif, B. °: Access to Cα backbone dynamics of biological solids by 13C T1 Relaxation and molecular dynamics simulation. J. Am. Chem. Soc. 137, 1094-1100 (2015)

Chevelkov, V.°, Xiang, S., Giller, K., Becker, S.T., Lange, A.D., Reif, B. : Perspectives for sensitivity enhancement in proton-detected solid-state NMR of highly deuterated proteins by preserving water magnetization. J. Biomol. NMR 61, 151-160 (2015)

Chromikova, V., Mader, A., Hofbauer, S., Göbl, C. , Madl, T. , Gach, J.S., Bauernfried, S., Furtmüller, P.G., Forthal, D.N., Mach, L., Obinger, C.°, Kunert, R.°: Introduction of germline residues improves the stability of anti-HIV mAb 2G12-IgM. Biochim. Biophys. Acta-Proteins Proteom., DOI: 10.1016/j.bbapap.2015.02.018 (2015)

Crevenna, A.H.°, Arciniega, M., Dupont, A., Mizuno, N., Kowalska, K., Lange, O.F. , Wedlich-Soeldner, R., Lamb, D.C.: Side-binding proteins modulate actin filament dynamics. eLife 4, DOI: 10.1101/008128 (2015)

Dames, S.A. °: One short cysteine-rich sequence pattern - two different disulfide-bonded structures - a molecular dynamics simulation study. J. Pept. Sci., DOI: 10.1002/psc.2765 (2015)

Edelmann, F.T. #, Niedner, A. #, Niessing, D. °: ASH1 mRNP-core factors form stable complexes in absence of cargo RNA at physiological conditions. RNA Biol. 12, 233-237 (2015)

Gersch, M., Famulla, K., Dahmen, M., Göbl, C. , Malik, I., Richter, K., Korotkov, V.S., Sass, P., Rübsamen-Schaeff, H., Madl, T. , Brötz-Oesterhelt, H.°, Sieber, S.A.°: AAA+ chaperones and acyldepsipeptides activate the ClpP protease via conformational control. Nat. Commun. 6:6320 (2015)

Hennig, J. , Andrésen, C., Museth, A.K., Lundström, P., Tibell, L.A.E., Jönsson, B.H.°: Local destabilization of the metal-binding region in human copper-zinc superoxide dismutase by remote mutations is a possible determinant for progression of ALS. Biochemistry 54, 323-333 (2015)

Hennig, J. , Warner, L. , Simon, B.H., Geerlof, A. , Mackereth, C.D., Sattler, M. °: Structural analysis of protein-RNA complexes in solution using NMR paramagnetic relaxation enhancements. Methods Enzymol., DOI: 10.1016/bs.mie.2015.02.006 (2015)

Hocking, H.G. , Häse, F., Madl, T. , Zacharias, M., Rief, M., Žoldák, G.°: A compact native 24-residue supersecondary structure derived from the villin headpiece subdomain. Biophys. J. 108, 678-686 (2015)

Pirovano, A.°, Brandmaier, S. , Huijbregts, M.A., Ragas, A.M., Veltman, K., Hendriks, A.J.: The utilisation of structural descriptors to predict metabolic constants of xenobiotics in mammals. Environ. Toxicol. Pharmacol. 39, 247-258 (2015)


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Riebold, M., Kozany, C., Freiburger, L. , Sattler, M. , Buchfelder, M., Hausch, F., Stalla, G.K., Paez-Pereda, M.°: A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing disease. Nat. Med., DOI: 10.1038/nm.3776 (2015)

Röhl, A., Tippel, F., Bender, E., Schmid, A.B., Richter, K., Madl, T. , Buchner, J.°: Hop/Sti1 phosphorylation inhibits its co-chaperone function. EMBO Rep. 16, 240-249 (2014)

Röhl, A., Wengler, D., Madl, T. , Lagleder, S., Tippel, F., Herrmann, M., Hendrix, J., Richter, K., Hack, G., Schmid, A.B., Kessler, H., Lamb, D.C.°, Buchner, J.°: Hsp90 regulates the dynamics of its cochaperone Sti1 and the transfer of Hsp70 between modules. Nat. Commun. 6:6655 (2015)

Sushko, Y.°, Novotarskyi, S., Körner, R., Vogt, J., Abdelaziz, A., Tetko, I.V. : Prediction-driven matched molecular pairs to interpret QSARs and aid the molecular optimization process. J. Cheminformatics 6:48 (2014)

Tharun, I.M., Nieto, L., Haase, C., Scheepstra, M., Balk, M., Möcklinghoff, S., Adriaens, W., Dames, S.A. , Brunsveld, L.°: Subtype-specific modulation of estrogen receptor-coactivator interaction by phosphorylation. ACS Chem. Biol. 10, 475-484 (2015)

Wang, X., Tang, Q., Popowicz, G.M. , Yang, B., Wang, Y.°: A mechanistic study into the epoxidation of carboxylic acid and alkene in a mono, di-acylglycerol lipase. Biochem. Biophys. Res. Commun. 460, 392-396 (2015)

Wittwer, M., Dames, S.A. °: Expression and purification of the natively disordered and redox sensitive metal binding regions of Mycobacterium tuberculosis protein kinase G. Protein Expr. Purif. 111, 68-74 (2015)


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Dembek, C.J. , Protzer, U. °: Mouse models for therapeutic vaccination against hepatitis B virus. Med. Microbiol. Immunol. 204, 95-102 (2015) [published online 2014]

Goldmann, T., Zeller, N., Raasch, J., Kierdorf, K., Frenzel, K., Ketscher, L., Basters, A., Staszewski, O., Brendecke, S.M., Spiess, A., Tay, T.L., Kreutz, C., Timmer, J., Mancini, G.M., Blank, T., Fritz, G., Biber, K., Lang, R., Malo, D., Merkler, D., Heikenwälder, M. , Knobeloch, K.P., Prinz, M.°: USP18 lack in microglia causes destructive interferonopathy of the mouse brain. EMBO J., DOI: 10.15252/embj.201490791 (2015)

Hellfritsch, J., Kirsch, J., Schneider, M., Perisic, T. , Wortmann, M., Frijhoff, J., Dagnell, M., Fey, T., Esposito, I. , Kölle, P., Pogoda, K., Ingold, I., Angeli, J.P., Kuhlencordt, P., Östman, A., Pohl, U., Beck, H.°, Conrad, M. °: Knockout of mitochondrial thioredoxin reductase stabilizes prolyl hydroxylase 2 and inhibits tumor growth and tumor-derived angiogenesis. Antioxid. Redox Signal. 22, 938-950 (2015)

Jacobi, C.°, Ayx, I., Fritsche, K., Piontek, G., Hoffmann, D. , Weirich, G., Knopf, A.: Potential impact of human papilloma virus on survival of basaloid squamous carcinoma of the head and neck. Oncotarget 6, 3462-3470 (2015)

Jors, S., Jeliazkova, P., Ringelhan, M. , Thalhammer, J., Dürl, S., Ferrer, J., Sander, M., Heikenwälder, M. , Schmid, R.M., Siveke, J.T., Geisler, F.°: Lineage fate of ductular reactions in liver injury and carcinogenesis. J. Clin. Invest., DOI: 10.1172/JCI78585 (2015)

Lambelé, M., Koppensteiner, H. , Symeonides, M., Roy, N.H., Chan, J., Schindler, M. , Thali, M.°: Vpu is the main determinant for tetraspanin downregulation in HIV-1 infected cells. J. Virol. 89, 3247-3255 (2015)

Loffredo-Verde, E., Abdel-Aziz, I.Z., Albrecht, J. , El Guindy, N.M., Yacob, M., Solieman, A.S., Protzer, U. , Busch, D.H. , Layland, L.E., Prazeres da Costa, C.U.: Schistosome infection aggravates HCV-related liver disease and induces changes in the regulatory T-cell phenotype. Parasite Immunol. 37, 97-104 (2015)

O'Connor, T. °, Borsig, L., Heikenwälder, M. °: CCL2-CCR2 signaling in disease pathogenesis. Endocr. Metab. Immune Disord. Drug Targets, accepted (2015)

Sautto, G.A., Wisskirchen, K. , Clementi, N., Castelli, M., Diotti, R.A., Graf, J. , Clementi, M., Burioni, R., Protzer, U. , Mancini, N.°: Chimeric Antigen Receptor (CAR)-engineered T cells redirected against Hepatitis C Virus (HCV) E2 glycoprotein. Gut, DOI: 10.1136/gutjnl-2014-308316 (2015)

Thiele, F. , Tao, S., Zhang, Y. , Muschaweckh, A. , Zollmann, T., Protzer, U. , Abele, R., Drexler, I.°: MVA-infected dendritic cells present CD4+ T-cell epitopes by endogenous MHC class II presentation pathways. J. Virol. 98, 2698-2709 (2015) [published online 2014]

Vassena, L., Giuliani, E., Koppensteiner, H. , Bolduan, S. , Schindler, M. , Doria, M.°: Hiv-1 NEF and VPU interfere with L-selectin (CD62L) cell surface expression to inhibit adhesion and signaling in infected CD4+ t lymphocytes. J. Virol. 89, 5687-5700 (2015)


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Vincendeau, M. , Göttesdorfer, I. , Schreml, J., Wetie, A. , Mayer, J., Greenwood, A.D., Helfer, M. , Kramer, S., Seifarth, W., Hadian, K. , Brack-Werner, R. , Leib-Mösch, C. °: Modulation of Human Endogenous Retrovirus (HERV) transcription during persistent and de novo HIV-1 infection. Retrovirol. 12:27 (2015)

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