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1 PUBLICATIONS I. JABIN 1- "Michael reaction of functionalized chiral cyclanone imines. Enantioselective synthesis of C 2 - symmetric cis-(1R,6R)-1,6-dimethylbicyclo[4.4.0]decane-3,8-dione" Pfau, M.; Jabin, I.; Revial, G. J. Chem. Soc. Perkin Trans. 1 1993, 17, 1935-1936. 2- "Diastereoselectivity and enantioselectivity in the addition of chiral imines of 2-methylcyclohexanone to crotonic and methacrylic acid esters" Jabin, I.; Revial, G.; Tomas, A.; Lemoine, P.; Pfau, M. Tetrahedron: Asymm. 1995, 6, 1795-1812. 3- "Enantioselective syntheses of (2S,4aS,8aR)-1,1,4a-trimethyldecahydronaphtha- len-2-ol [(–)-TMD], (4aS,8aR)-5,5,8a-trimethyloctahydronaphthalen-2(1H)-one, and (–)-Polywood , through Michael- type reaction of chiral imines" Jabin, I.; Revial, G.; Melloul, K.; Pfau, M. Tetrahedron: Asymm. 1997, 8, 1101-1109. 4- "Reaction of cyclohexanones imines with substituted nitroolefins. New synthesis of tetrahydroindole derivatives" Lim, S.; Jabin, I.; Revial, G. Tetrahedron Lett. 1999, 40, 4177-4180. 5- "Tautomerism of ,-ethylenic imines and their reactivity toward electrophilic olefins" Jabin, I.; Revial, G.; Pfau, M.; Decroix, B.; Netchitaïlo, P. Org. Lett. 1999, 1, 1901-1904. 6- "Synthetic approaches to 3-substituted-5'-(N-pyridiniummethyl)-4',5'-dihydropsoralen" Jabin, I.; Heindel, N.D.; Rapp, R.D.; Laskin, J.D. J. Het. Chem. 2000, 37, 31-39. 7- "Enantioselective synthesis of (+)--vetivone through the Michael reaction of chiral imines" Revial, G.; Jabin, I.; Pfau, M. Tetrahedron: Asymm. 2000, 11, 4975-4983. 8- "Reaction of Cyclohexanone Benzylimines with Ethylidenemalonate Diesters. Diphenyl 2- ethylidenemalonate: a Highly Electrophilic Synthetic Equivalent of Crotonic Esters" Jabin, I.; Revial, G.; Monnier-Benoit, N.; Netchitaïlo, P. J. Org. Chem. 2001, 66, 256-261. 9- "Enantioselective Imine Michael Reaction for the Preparation of the (8'R,8a'S)-8,8a'-Dimethyl- 1',3',4',7',8',8a'-hexahydrospiro[1,3-dioxolane-2,2'(6'H)naphthalen]-6'-one Building Block. A formal synthesis of (+)-Valencenol" Revial, G.; Jabin, I.; Redolfi, M.; Pfau, M. Tetrahedron: Asymm. 2001, 12, 1683-1688. 10- "Synthetic approaches to 4,8-dimethyl-5'-(N-pyridiniummethyl)-4',5'-dihydropsoralens and 4,8- dimethyl-5'-(N-aminomethyl)-4',5'-dihydropsoralensWhittemore, M.S.; Heindel, N.D.; Jabin, I.; Guillon, C.; McNeel, T.E.; Rapp, R.D.; Heck, D.E.; Laskin, J.D. J. Het. Chem. 2001 38, 909-916.

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  • 1

    PUBLICATIONS I. JABIN

    1- "Michael reaction of functionalized chiral cyclanone imines. Enantioselective synthesis of C2-

    symmetric cis-(1R,6R)-1,6-dimethylbicyclo[4.4.0]decane-3,8-dione"

    Pfau, M.; Jabin, I.; Revial, G. J. Chem. Soc. Perkin Trans. 1 1993, 17, 1935-1936.

    2- "Diastereoselectivity and enantioselectivity in the addition of chiral imines of 2-methylcyclohexanone

    to crotonic and methacrylic acid esters"

    Jabin, I.; Revial, G.; Tomas, A.; Lemoine, P.; Pfau, M. Tetrahedron: Asymm. 1995, 6, 1795-1812.

    3- "Enantioselective syntheses of (2S,4aS,8aR)-1,1,4a-trimethyldecahydronaphtha- len-2-ol [()-TMD],

    (4aS,8aR)-5,5,8a-trimethyloctahydronaphthalen-2(1H)-one, and ()-Polywood, through Michael-

    type reaction of chiral imines"

    Jabin, I.; Revial, G.; Melloul, K.; Pfau, M. Tetrahedron: Asymm. 1997, 8, 1101-1109.

    4- "Reaction of cyclohexanones imines with substituted nitroolefins. New synthesis of tetrahydroindole

    derivatives"

    Lim, S.; Jabin, I.; Revial, G. Tetrahedron Lett. 1999, 40, 4177-4180.

    5- "Tautomerism of ,-ethylenic imines and their reactivity toward electrophilic olefins"

    Jabin, I.; Revial, G.; Pfau, M.; Decroix, B.; Netchitalo, P. Org. Lett. 1999, 1, 1901-1904.

    6- "Synthetic approaches to 3-substituted-5'-(N-pyridiniummethyl)-4',5'-dihydropsoralen"

    Jabin, I.; Heindel, N.D.; Rapp, R.D.; Laskin, J.D. J. Het. Chem. 2000, 37, 31-39.

    7- "Enantioselective synthesis of (+)--vetivone through the Michael reaction of chiral imines"

    Revial, G.; Jabin, I.; Pfau, M. Tetrahedron: Asymm. 2000, 11, 4975-4983.

    8- "Reaction of Cyclohexanone Benzylimines with Ethylidenemalonate Diesters. Diphenyl 2-

    ethylidenemalonate: a Highly Electrophilic Synthetic Equivalent of Crotonic Esters"

    Jabin, I.; Revial, G.; Monnier-Benoit, N.; Netchitalo, P. J. Org. Chem. 2001, 66, 256-261.

    9- "Enantioselective Imine Michael Reaction for the Preparation of the (8'R,8a'S)-8,8a'-Dimethyl-

    1',3',4',7',8',8a'-hexahydrospiro[1,3-dioxolane-2,2'(6'H)naphthalen]-6'-one Building Block. A formal

    synthesis of (+)-Valencenol"

    Revial, G.; Jabin, I.; Redolfi, M.; Pfau, M. Tetrahedron: Asymm. 2001, 12, 1683-1688.

    10- "Synthetic approaches to 4,8-dimethyl-5'-(N-pyridiniummethyl)-4',5'-dihydropsoralens and 4,8-

    dimethyl-5'-(N-aminomethyl)-4',5'-dihydropsoralens

    Whittemore, M.S.; Heindel, N.D.; Jabin, I.; Guillon, C.; McNeel, T.E.; Rapp, R.D.; Heck, D.E.; Laskin,

    J.D. J. Het. Chem. 2001 38, 909-916.

  • 2

    11- "A straightforward approach to the galanthan ring system using the imine Michael reaction

    followed by a radical cyclization"

    Jabin, I.; Netchitalo, P. Tetrahedron Lett. 2001, 42, 7823-7827.

    12- "Cell-impermeant pyridinium derivatives of psoralens as inhibitors of keratinocyte growth"

    Mariano, T.M.; Vetrano, A.M.; Gentile, S.L.; Heck, D.E.; Whittemore, M.S.; Guillon, C.D.; Jabin, I.;

    Rapp, R.D.; Heindel, N.D.; Laskin, J.D. Biochemical Pharm. 2002, 63, 3139.

    13- "Use of -aminoesters as chiral auxiliaries in the enantioselective Michael alkylation of chiral

    imines"

    Jabin, I.; Revial, G.; Pfau, M.; Netchitalo, P. Tetrahedron: Asymm. 2002, 13, 563-567.

    14- "Aromatization of 1,6,7,7a-tetrahydro-2H-indol-2-ones by a novel process. Preparation of key-

    intermediate methyl 1-benzyl-5-methoxy-1H-indole-3-acetate and the syntheses of serotonin,

    melatonin, and bufotenin"

    Revial, G.; Jabin, I.; Lim, S.; Pfau, M. J. Org. Chem. 2002, 67, 2252-2256.

    15- "Reaction of vinyl triflates of -keto esters with primary amines: efficient synthesis of aziridine

    carboxylates"

    Tranchant, M. J.; Dalla, V.; Jabin, I.; Decroix, B. Tetrahedron 2002, 58, 8425-8432.

    16- "Stereoselective synthesis of 5,6-disubstituted-3,4-dihydro-1H-pyridin-2-ones, a new class of non-

    biaryl atropisomeric compounds. Part 1"

    Jabin, I.; Monnier-Benoit, N.; Le Gac, S.; Netchitalo, P. Tetrahedron Lett. 2003, 44, 611-614.

    17- "First C3v-symmetrical calix[6](aza)crown"

    Jabin, I.; Reinaud, O. J. Org. Chem. 2003, 68, 3416-3419.

    18- "Michael reaction of unsubstituted aromatic chiral imines with substituted unsaturated acid esters"

    Monnier-Benoit, N.; Jabin, I.; Tomas, A.; Selkti, M.; Revial, G. Tetrahedron: Asymm. 2003, 14, 2747-

    2753.

    19- "Stereoselective synthesis of new classes of atropisomeric compounds through the tandem imine

    Michael reaction-azacyclization process. Part 2" .

    Le Gac, S.; Monnier-Benoit, N.; Doumampouom Metoul, L.; Petit, S.; Jabin, I. Tetrahedron: Asymm.

    2004, 15, 139-145.

    20- Article faisant la couverture du numro du 23 juillet 2004 du J. Org. Chem.:

    "A novel C3v-symmetrical calix[6](aza)cryptand with a remarkably high and selective affinity for small

    ammoniums"

    Darbost, U.; Giorgi, M.; Reinaud, O.; Jabin, I. J. Org. Chem. 2004, 69, 4879-4884.

    21- "A novel receptor based on a C3v-symmetrical PN3-calix[6]cryptand"

    Zeng, X.; Hucher, N.; Reinaud, O.; Jabin, I. J. Org. Chem. 2004, 69, 6886-6889.

  • 3

    22- "X-ray and solution structure of the first Zn funnel complex based on a calix[6]aza-cryptand"

    Darbost, U.; Zeng, X.; Rager, M.-N.; Giorgi, M.; Jabin, I.; Reinaud, O. Eur. J. Inorg. Chem. 2004, 4371-

    4374.

    23- "Synthesis and conformational study of the first triply-bridged calix[6]azatubes"

    Le Gac, S.; Zeng, X.; Reinaud, O.; Jabin, I. J. Org. Chem. 2005, 70, 1204-1210.

    24- "A calix[6]arene receptor rigidified by a self-assembled tri-ammonium cap: X-ray and NMR

    characterization of the binding of polar neutral guests "

    Darbost, U.; Giorgi, M.; Hucher, N.; Jabin, I.; Reinaud, O. Supramol. Chem. 2005, 17, 243-250.

    25- "Calix[6]tren and Copper(II): A new generation of funnel complexes on the way to redox calix-zymes"

    Izzet,G.; Douziech, B.; Prang, T.; Tomas, A.; Jabin, I.; Le Mest, Y.; Reinaud, O. Proc. Nat. Acad. Sci.

    2005, 102, 6831-6836.

    26- "Polarizing a hydrophobic cavity for the efficient binding of organic guests: the case of calix[6]tren, a

    highly efficient and versatile receptor for neutral or cationic species"

    Darbost, U.; Rager, M-.N.; Petit, S.; Jabin, I.; Reinaud, O. J. Am. Chem. Soc. 2005, 127, 8517-8525.

    27- "Optically pure calix[6]tris-ammoniums: syntheses and host-guest properties toward neutral guests"

    Darbost, U.; Zeng, X.; Giorgi, M.; Jabin, I. J. Org. Chem. 2005, 70, 10552-10560.

    28- "First enantiopure calix[6]aza-cryptand: synthesis and chiral recognition properties toward neutral

    molecules"

    Garrier, E.; Le Gac, S.; Jabin, I. Tetrahedron: Asymm. 2005, 16, 3767-3771.

    29- "Allosterically coupled double induced fit for a 1+1+1+1 self-assembly of a calix[6]tris-amine, a

    calix[6]tris-acid and their respective guest "

    Le Gac, S.; Marrot, J.; Reinaud, O.; Jabin, I. Angew. Chem., Int. Ed. Engl. 2006, 45, 3123-3126.

    30- "Efficient synthesis of calix[6]tmpa: a new calix[6]aza-cryptand with unique conformational and

    host-guest properties"

    Zeng, X.; Coquire, D.; Alenda, A.; Garrier, E.; Prang, T.; Li, Y.; Reinaud, O.; Jabin, I. Chem. Eur. J.

    2006, 12, 6393-6402.

    31- "Access to Chiral N-Substituted 1,4-Dihydropyridines Through the One-Pot Domino Michael-

    Azacyclization Process"

    Monnier-Benoit, N.; Jabin, I.; Netchitalo, P. Lett. Org. Chem. 2006, 3, 549-553.

    32- "Efficient Synthesis and Host-guest Properties of a New Class of Calix[6]aza-cryptands"

    Le Gac, S.; Zeng, X.; Girardot, C.; Jabin, I. J. Org. Chem. 2006, 71, 9233-9236.

  • 4

    33- "First insights into the electronic properties of a Cu(II) center embedded in the PN3 cap of a

    calix[6]arene-based ligand"

    Izzet, G.; Zeng, X.; Over, D.; Douziech, B.; Zeitouny, J.; Giorgi, M.; Jabin, I.; Le Mest, Y.; Reinaud, O.

    Inorg. Chem. 2007, 46, 375-377.

    34- "Allosteric Tuning of the Intra-Cavity Binding Properties of a Calix[6]arene through External Binding

    to a ZnII Center Coordinated to Amino Side Chains"

    Darbost, U.; Snque, O.; Li, Y.; Bertho, G.; Marrot, J.; Rager, M.-N.; Reinaud, O.; Jabin, I. Chem. Eur.

    J. 2007, 13, 2078-2088.

    35- "Synthesis of 2,4-dimethyl-cyclohex-3-ene carboxaldehyde derivatives with potential olfactory

    properties"

    Monnier-Benoit P., Jabin I., Jaubert, J.-N.; Netchitalo P.; Goyau B. C. R. Chimie 2007, 10, 259-267.

    36- Article faisant la couverture de Supramol. Chem.:

    "Calix[6]arene Tris-carboxylic Acid Derivatives: X-ray and NMR Characterization of their Remarkable

    Host-guest Properties Toward Ammonium Ions"

    Le Gac, S.; Giorgi, M.; Jabin, I. Supramol. Chem. 2007, 19, 185-197.

    37- Article faisant la couverture de Tetrahedron:

    "Self-assembly via ionic interactions of calix[6]arene based receptors displaying remarkable host-

    guest properties toward neutral guests"

    Le Gac, S.; Luhmer, M.; Reinaud, O.; Jabin, I. Tetrahedron 2007, 63, 10721-10730.

    38- "Syntheses and study of calix[6]cryptamides: a novel class of heteroditopic receptors displaying

    versatile host-guest properties toward neutral species or organic associated ion-pair salts"

    Le Gac, S.; Jabin, I. Chem. Eur. J. 2008, 14, 548-557.

    39- "Highly selective synthesis of a 1,3,5-tris-protected calix[6]arene type molecular platform through

    coordination and host-guest chemistry"

    Le Gac, S.; Marrot, J.; Jabin, I. Chem. Eur. J. 2008, 14, 3316-3322.

    40- "Synthesis and host-guest properties of a calix[6]arene based receptor closed by an internal ion-

    paired cap"

    Richard, J.A.; Pamart, M.; Hucher, N.; Jabin, I. Tetrahedron Lett. 2008, 49, 3848-3852.

    41- "Calix[6]tris-(thio)ureas: heteroditopic receptors for the cooperative binding of organic ion-pairs"

    Hamon, M.; Mnand, M.; Le Gac, S.; Luhmer, M.; Dalla, V.; Jabin, I. J. Org. Chem. 2008, 73, 7067-

    7071.

    42- "Dioxygen Activation at a Mononuclear Cu(I) Center Embedded in the Calix[6]arene-Tren Core"

    Izzet, G.; Zeitouny, J.; Akdas-Killig, H.; Frapart, Y.; Mnage, S.; Douziech, B.; Jabin, I.; Le Mest, Y.;

    Reinaud, O. J. Am. Chem. Soc. 2008, 130, 9514-9523.

  • 5

    43- "C3v-Symmetrical Calix[6]arenes"

    Le Gac, S.; Marrot, J.; Jabin, I. Synfacts 2008, 6, 583.

    44- " Second generation of calix[6]aza-cryptands: synthesis of heteroditopic receptors for organic ion

    pairs"

    Le Gac, S.; Mnand, M.; Jabin, I. Org. Lett. 2008, 10, 5195-5198.

    45- "Synthesis of the First Calix[6]crypturea via a Versatile Tris-azide Precursor"

    Mnand, M.; Jabin, I. Org. Lett. 2009, 11, 673-676.

    46- Article faisant la couverture d'Org. Biomol. Chem.:

    "Biomimetic and self-assembled calix[6]arene-based receptors for neutral molecules"

    Coquire, D.; Le Gac, S.; Darbost, U.; Snque, O.; Jabin, I.; Reinaud, O. Org. Biomol. Chem., 2009,

    7, 24852500.

    47- "Induced fit encapsulation by a 1,3,5-alternate calix[6]arene"

    Mnand, M.; Leroy, A.; Marrot, J.; Luhmer M.; Jabin, I. Angew. Chem., Int. Ed. Engl. 2009, 48,

    5509-5512.

    48- "Dramatic Effect of a Protein-like Cavity on Dissociative vs. Associative Copper Redox Chemistry"

    Le Poul, N.; Douziech, B.; Zeitouny, J.; Thiabaud, G.; Colas, H.; Conan, F.; Cosquer, N.; Jabin, I.;

    Lagrost, C.; Hapiot, P.; Reinaud, O.; Le Mest Y. J. Am. Chem. Soc. 2009, 131, 1780017807.

    49- "Acid-base Controllable Recognition Properties of a Highly Versatile Calix[6]crypturea"

    Mnand, M.; Jabin, I. Chem. Eur. J. 2010, 16, 2159-2169.

    50- "Calix[6]arene Based Cascade Complexes of Organic Ion-Triplets Stable in a Protic Solvent"

    Moerkerke, S; Mnand, M.; Jabin, I. Chem. Eur. J. 2010, 16, 11712-11719.

    51- "An Allosteric Heteroditopic Receptor for Neutral Guests and Contact Ion Pairs with a Remarkable

    Selectivity for Ammonium Fluoride Salts"

    Lascaux, A.; Le Gac, S.; Wouters, J.; Luhmer, M.; Jabin, I. Org. Biomol. Chem. 2010, 8, 4607-4616.

    52- "Auto-catalyzed "electroclick" immobilization of a copper complex onto self-assembled

    monolayers on a gold electrode"

    Gomila, A.; Le Poul, N.; Cosquer, N.; Kerbaol, J.-M.; Nol, J.-M.; Reddy, M. T.; Jabin, I.; Reinaud, O.;

    Conan, F.; Le Mest, Y. Dalton Trans. 2010, 39, 11516-11518.

    53- Article slectionn comme Hot Paper (Fv. 2011) dans Org. Biomol. Chem.

    "Allosterically driven self-assemblies of interlocked calix[6]arene receptors"

    Le Gac, S.; Picron, J.-F.; Reinaud, O.; Jabin, I. Org. Biomol. Chem. 2011, 9, 2387-2396.

    54- "Ru-TAP complexes with btz and pytz ligands: novel candidates as photooxidizing agents"

    Mattiuzzi, A.; Jabin, I.; Moucheron, C.; Kirsch-De Mesmaeker, A. Dalton Trans. 2011, 40, 7395-

    7402.

  • 6

    55- "Structure-Activity Relationship Analyses of Glycyrrhetinic Acid Derivatives as Anticancer Agents"

    Lallemand, B.; Gelbcke, M.; Dubois, J.; Prvost, M.; Jabin, I.; Kiss, R. Mini-Rev. Med. Chem. 2011,

    11, 881-887.

    56- "Second Generation Calix[6]trenamides: Highly Selective Graftable Receptors for Neutral Guests

    and Contact Ion Pairs "

    Lascaux, A.; Delahousse, G.; Ghostin, J.; Bouillon, J.-P.; Jabin, I. Eur. J. Org. Chem. 2011, 5272-5278.

    57- Article slectionn comme Hot Paper (Aot 2011) dans Org. Biomol. Chem.

    "Acid-base modulation of a versatile heteroditopic calix[6]arene based receptor"

    Cornut, C.; Marrot, J.; Wouters, J.; Jabin, I. Org. Biomol. Chem. 2011, 9, 6373-6384.

    58- "New structure activity relationship (SAR) of novel anticancer glycyrrhetinic acid derivatives"

    Lallemand, B.; Gelbcke, M.; Dubois, J.; Jabin, I.; Kiss; R. Ann. Oncol. 2011, 22, 30.

    59- "N-(2-{3-[3,5-bis(trifluoromethyl)phenyl]ureido}ethyl)-glycyrrhetinamide (6b): A Novel Anticancer

    Glycyrrhetinic Acid Derivative that Targets the Proteasome and Displays Anti-Kinase Activity"

    Lallemand, B.; Chaix, F.; Bury, M.; Bruyre, C.; Ghostin, J.; Becker, J.; Delporte, C.; Gelbcke, M.;

    Mathieu, V.; Dubois, J.; Prvost, M.; Jabin, I.; Kiss, R. J. Med. Chem., 2011, 54, 6501-6513.

    60- Ipso-nitration of calix[6]azacryptands: intriguing effect of the small rim capping pattern on the

    large rim substitution selectivity

    Lejeune, M.; Picron, J.-F.; Mattiuzzi, A.; Lascaux, A.; De Cesco, S.; Brugnara, A.; Thiabaud, G.;

    Darbost, U.; Colasson, B.; Reinaud, O.; Jabin, I. J. Org. Chem., 2012, 77, 3838-3845.

    61- DYRK1A Kinase Inhibitors with Emphasis on Cancer

    Ionescu, A.; Dufrasne, F.; Gelbcke, M.; Jabin, I.; Kiss, R.; Lamoral-Theys, D. Mini-Rev. Med. Chem.

    2012, 12, 1315-1329.

    62- Reductive electrografting of calix[4]arenediazonium salts onto surfaces: Anchoring versatile

    platforms for spatially-controlled functionalization

    Mattiuzzi, A.; Jabin, I.; Mangeney, C.; Roux, C.; Reinaud, O.; Santos, L.; Bergamini, J.F.; Hapiot, P.;

    Lagrost C. Nat. Commun. 2012, 3, 1130.

    63- Synthesis and Plasma Pharmacokinetics in CD-1 Mice of a 18-glycyrrhetinic Acid Derivative

    Displaying Anticancer Activity

    Lallemand, B.; Ouedraogo, M.; Wauthoz, N.; Lamkami, T.; Mathieu, V.; Jabin, I.; Amighi, K.; Kiss, R.;

    Dubois, J.; Goole J. J. Pharm. Pharmacol. 2012, DOI: 10.1111/j.2042-7158.2012.01603.x.

  • 7

    PUBLICATIONS G. EVANO

    1- Selective N-Dealkylation of Tertiary Amines Derived from Phenylglycinol or Ephedrine Family

    Agami, C.; Couty, F.; Evano, G. Tetrahedron Lett. 1999, 40, 3709-3712.

    2- Synthesis of -Substituted Allylic Amines via a Modified Bruylants Reaction

    Agami, C.; Couty, F.; Evano, G. Org. Lett. 2000, 2, 2085-2088.

    3- SN2 Regio and Stereoselective Alkylation of Allylic and Propargylic Mesylates Linked to a N-Boc

    Oxazolidine using Organocuprates

    Agami, C.; Couty, F.; Evano, G.; Mathieu, H. Tetrahedron, 2000, 56, 367-376.

    4- Claisen Rearrangement of Allylic Alcohols Prepared through N-Boc-2-acyloxazolidine

    Methodology. Application to the Synthesis of Trisubstituted Cyclopropanes

    Agami, C.; Couty, F.; Evano, G. Tetrahedron Lett. 2000, 41, 8301-8305.

    5- Enantioselective Synthesis of 2-Substituted-N-Boc--4,5-piperidines

    Agami, C.; Couty, F.; Evano, G. Tetrahedron : Asymmetry, 2000, 11, 4639-4643.

    6- Claisen Rearrangement of Allylic and Propargylic Alcohols Prepared through N-Boc-2-

    Acyloxazolidines Methodology. Application to the Synthesis of Original Chiral Building Blocks

    Agami, C.; Couty, F.; Evano, G. Eur. J. Org. Chem. 2002, 29-38.

    7- Some Uses of N-Boc-2-acyloxazolidines in Asymmetric Synthesis

    Couty, F.; Evano, G.; Matthieu, H.; Rabasso, N.; Venier, O. l'Actualit Chimique, 2002, 249, 13-18.

    8- A Straightforward Synthesis of Enantiopure 2-Cyanoazetidines from -Aminoalcohols

    Agami, C.; Couty, F.; Evano, G. Tetrahedron: Asymmetry 2002, 13, 297-302.

    9- Enantioselective Synthesis of Clavepictine analogues and Evaluation of their Cytotoxic Activity

    Agami, C.; Couty, F.; Evano, G.; Darro, F.; Kiss, R. Eur. J. Org. Chem. 2003, 2062-2070.

    10- Synthesis of enantiopure azetidine-2-carboxylic acids and their incorporation into peptides

    Couty, F.; Evano, G.; Rabasso, N. Tetrahedron: Asymmetry 2003, 14, 2407-2412.

    11- A Convergent Synthesis of the Macrocyclic Core of Cytotrienins: Application of RCM for

    Macrocyclization

    Evano, G.; Schaus, J. V.; Panek, J. S. Org. Lett. 2004, 5, 525-528.

    12- Synthesis of Chiral Non Racemic Azetidines

    Couty, F.; Evano, G.; Prim, D. Minireviews in Organic Chemistry 2004, 1, 133-148.

  • 8

    13- Synthesis and Reactivity of Enantiomerically Pure N-Alkyl-2-alkenyl Azetidinium Salts

    Couty, F.; Durrat, F.; Evano, G.; Prim, D. Tetrahedron Lett. 2004, 45, 7525-7528.

    14- General Route to a New Class of Homochiral Azetidine-Derived 1,2-Diamines

    Couty, F.; Evano, G.; Prim, D.; Marrot, J. Eur. J. Org. Chem., 2004, 3893-3897.

    15- N-Cyanomethyl--chloroamines: A Convenient Source of Aziridinium Ions

    Couty, F.; Evano, G.; Prim, D. Tetrahedron Lett. 2005, 46, 2253-2257.

    16- Azetidine motifs as ligand in the Pd(II) complexes series

    Keller, L.; Vargas Sanchez, M.; Prim, D.; Couty, F.; Evano, G.; Marrot, J. J. Organomet. Chem. 2005,

    690, 2306-2311.

    17- Regioselective Nucleophilic Opening of Azetidinium Ions

    Couty, F.; Durrat, F.; Evano, G. Synlett 2005, 1666-1670.

    18- Azetidinic Amino Acids: Stereocontrolled Synthesis and Pharmacological Characterization as

    Ligands for the Glutamate Receptors and Transporters

    Bruner-Osborne, H.; Bunch, L. Chopin, N., Couty, F.; Evano, G.; Jensen, A. A.; Kusk, M.; Nielsen,

    B.; Rabasso, N. Org. Biomol. Chem. 2005, 3926-3936.

    19- Practical Asymmetric Preparation of Azetidine-2-carboxylic Acid

    Couty, F.; Evano, G.; Vargas-Sanchez, M.; Bouzas, G. J. Org. Chem., 2005, 70, 9028-9031.

    20- Total Synthesis of Reblastatin

    Wrona, I.; Gabarda, A.; Evano, G.; Panek, J. S. J. Am. Chem. Soc., 2005, 127, 15026-15027 (repris

    dans Synfacts, 2006, 312).

    21- 3-Aminopyrrolidines via Ring Rearrangement of 2-Aminomethylazetidines. Synthesis of (-)-

    Absouline

    Vargas-Sanchez, M.; Couty, F.; Evano, G.; Prim, D.; Marrot, J. Org. Lett. 2005, 6, 5861-5864.

    22- Stereocontrolled Synthesis of 3-Substituted Azetidinic Amino Acids

    Sivaprakasam, M.; Couty, F.; Evano, G.; Srinivas, B.; Sridhar, R.; Rama Rao, K. Synlett 2006, 781-

    785.

    23- N-Cyanomethyl--chloro amines: chiral building blocks for the synthesis of azacrown ethers

    Couty, F.; Evano, G.; Menguy, L.; Steimetz, V.; Toumi, M. Tetrahedron Lett. 2006, 47, 4817-4821.

    24- Nucleophilic Ring-Opening of Azetidinium Ions: Insights into Regioselectivity

    Couty, F.; David, O.; Durrat, F.; Evano, G.; Lakhdar, S.; Marrot, J.; Vargas-Sanchez, M. Eur. J. Org.

    Chem. 2006, 3479-3490.

    25- Ring Expansions of 2-Alkenylazetidinium Salts a New Route to Pyrrolidines and Azepanes

    Couty, F.; Durrat, F.; Evano, G.; Marrot, J. Eur. J. Org. Chem. 2006, 4214-4223.

  • 9

    26- Azetidine-2-Carboxylic Acid. From Lily of the Valley to Key Pharmaceuticals. A Jubilee Review

    Couty, F.; Evano, G. Org. Prep. Proced. Int. 2006, 38, 427-465.

    27- The Reaction of Azetidines with Chloroformates

    Vargas-Sanchez, M.; Lakhdar, S.; Couty, F.; Evano, G. Org. Lett. 2006, 8, 5501-5504.

    28- Article faisant la couverture dAngew. Chem. Int. Ed. :

    Total Synthesis of Paliurine F

    Toumi, M.; Couty, F.; Evano, G. Angew. Chem. Int. Ed. 2007, 46, 572-575 (repris dans Synfacts,

    2007, 571).

    29- A Straighforward Synthesis of 3-Substituted Azetidinic Amino Acids

    Sivaprakasam, M.; Couty, F.; Evano, G.; Srinivas, B.; Sridhar, R.; Rama Rao, K. Arkivoc, 2007, Part

    (x): Commemorative Issue in Honor of Prof. Alain Krief on the occasion of his 65th Anniversary,

    71-93.

    30- Article faisant la couverture du J. Org. Chem. :

    Total Synthesis of the Cyclopeptide Alkaloid Abyssenine A. Application of Inter- and

    Intramolecular Copper-Mediated Coupling Reactions in Organic Synthesis

    Toumi, M.; Couty, F.; Evano, G. J. Org. Chem., 2007, 72, 9003-9009 (repris dans Synfacts, 2008,

    338).

    31- Eight Steps Total Synthesis of the Cyclopeptide Alkaloid Mucronine E

    Toumi, M.; Couty, F.; Evano, G. Synlett, 2008, 29-32.

    32- A Practical Route to Enantiopure 3-Hydroxy-pyrrolidines: Application to a Straightforward

    Synthesis of (-)-Bulgecinine

    Toumi, M.; Couty, F.; Evano, G. Tetrahedron Lett. 2008, 49, 1175-1179.

    33- Total Synthesis of the Cyclopeptide Alkaloid Paliurine E. Insights into Macrocyclization by Ene-

    enamide RCM

    Toumi, M.; Couty, F.; Evano, G. J. Org. Chem. 2008, 73, 1270-1281.

    34- Rearrangement of 2-Hydroxyalkylazetidines into 3-Fluoropyrrolidines

    Drouillat, B.; Couty, F.; David, O.; Evano, G.; Marrot, J. Synlett 2008, 1345-1348.

    35- Ring Expansion of 2-(-Hydroxyalkyl)azetidines: A Synthetic Route to Functionalized Pyrrolidines

    Durrat, F.; Vargas-Sanchez, M.; Couty, F.; Evano, G.; Marrot, J. Eur. J. Org. Chem. 2008, 3286-

    3297.

    36- Copper-Mediated Coupling Reactions and Their Applications in Natural Products and Designed

    Biomolecules Synthesis

    Evano, G.; Blanchard, N.; Toumi, M. Chem. Rev. 2008, 108, 3054-3131.

  • 10

    37- Des Acides Amins et du Cuivre(I) pour la Synthse dAlcalodes Cyclopeptidiques

    Evano, G. l'Actualit Chimique, 2008, 322, 20-26.

    38- Copper-Catalyzed Cyclization of Iodo-tryptophans: A Straightforward Synthesis of Pyrroloindoles

    Coste, A.; Toumi, M.; Wright, K.; Razafimahalo, V.; Couty, F.; Marrot, J.; Evano, G. Org. Lett.

    2008, 10, 3841-3844.

    39- Total Synthesis of Chaetominine

    Toumi, M.; Couty, F.; Marrot, J.; Evano, G. Org. Lett. 2008, 10, 5027-5030.

    40- TMC-95A-D: Chemistry and Biology

    Coste, A.; Couty, F.; Evano, G. C. R. Chimie 2008, 11, 1544-1573, Numro spcial Natural

    Products with Anticancer Properties.

    41- Copper-Mediated Coupling of 1,1-Dibromo-1-alkenes with Nitrogen Nucleophiles: A General

    Method for the Synthesis of Ynamides

    Coste, A.; Karthikeyan, G.; Couty, F.; Evano, G. Angew. Chem. Int. Ed. 2009, 48, 4381-4385 (repris

    dans Synfacts, 2009, 907).

    42- Copper-Catalyzed Cyclization Reactions for the Synthesis of Alkaloids

    Evano, G.; Toumi, M. Coste, A. Chem. Commun. 2009, 4166-4175.

    43- A General Route to Cyclopeptide Alkaloids: Total Syntheses and Biological Evaluation of

    Paliurines E and F, Ziziphines N and Q, Abyssenine A, Mucronine E, and Analogues

    Toumi, M.; Rincheval, V.; Young, A.; Gergeres, D.; Turos, E.; Couty, F.; Mignotte, B.; Evano, G. Eur.

    J. Org. Chem. 2009, 3368-3386.

    44- Second-Generation, Biomimetic Total Synthesis of Chaetominine

    Coste, A.; Karthikeyan, G.; Couty, F.; Evano, G. Synthesis 2009, 2927-2934, Numro spcial

    Natural Product Synthesis.

    45- Synthesis of Ketene N,N-Acetals by Copper-Catalyzed Double-Amidation of 1,1-Dibromo-1-

    alkenes

    Coste, A.; Couty, F.; Evano, G. Org. Lett. 2009, 11, 4454-4457.

    46- Azetidines: New Tools for the Synthesis of Nitrogen Heterocycles

    Couty, F.; Evano, G. Synlett 2009, 3053-3064.

    47- Ynamides: Versatile Tools in Organic Synthesis

    Evano, G.; Coste, A.; Jouvin, K. Angew. Chem. Int. Ed. 2010, 49, 2840-2859.

    48- Copper-Mediated Homocoupling of Vinyl Dibromides to Symmetrical Diynes

    Coste, A.; Couty, F. Evano, G. Synthesis 2010, 1500-1504.

  • 11

    49- Synthesis of the Azetidinyl-Thiazoline Fragment of Vioprolides A and C

    Chopin, N.; Couty, F.; Evano, G. Lett. Org. Chem. 2010, 7, 353-359.

    50- Synthesis of Ynamides by Copper-Mediated Coupling of 1,1-Dibromo-1-alkenes with Nitrogen

    Nucleophiles. Preparation of N-Benzyl-N-4-toluenesulfonyl-phenylethynylamine

    Coste, A.; Couty, F.; Evano, G. Org. Synth. 2010, 87, 231-244.

    51- Copper-Catalyzed Alkynylation of Amides with Potassium Alkynyltrifluoroborates: A Room-

    Temperature, Base-Free Synthesis of Ynamides

    Jouvin, K.; Couty, F.; Evano, G. Org. Lett. 2010, 12, 3272-3275.

    52- Organic Azides Syntheses and Applications. By S. Brse and K. Banert

    Evano, G. Angew. Chem. Int. Ed. 2010, 49, 6025.

    53- Vinyl Dibromides: Versatile Partners in Cross-Coupling Reactions

    Legrand, F.; Jouvin, K. Evano, G. Isr. J. Chem. 2010, 50, 588-604. Numro spcial Metal-Catalyzed

    Cross-Coupling Reactions.

    54- Copper-Mediated Cross-Coupling of 1,1-Dibromo-1-alkenes with Dialkylphosphites: a Convenient

    Synthesis of 1-Alkenylphosphonates

    Evano, G.; Tadiparthi, K.; Couty, F. Chem. Comm. 2011, 47, 179-181. Numro spcial Emerging

    Investigators.

    55- Highly Regio- and Stereo- selective Nickel-Catalyzed Addition of Dialkylphosphites to Ynamides:

    an Efficient Synthesis of -Amino Vinylphosphonates

    Fadel, A.; Legrand, F.; Evano, G.; Rabasso, N. Adv. Synth. Catal. 2011, 353, 263-267.

    56- Copper-Catalysed N-Alkynylation of Benzimidazoles and Indazoles

    Jouvin, K.; Evano, G. Chimica Oggi-Chemistry Today 2011, 29, 31-33.

    57- Copper-Catalyzed Oxidative Alkynylation of Diaryl Imines with Terminal Alkynes: A Facile

    Synthesis of Ynimines

    Laouiti, A.; Rammah, M. M.; Rammah, M. B.; Marrot, J.; Couty, F.; Evano, G. Org. Lett. 2012, 14,

    6-9.

    58- Click-Alkynylation of N- and P-Nucleophiles by Oxidative Cross-Coupling with Alkynylcopper

    Reagents: a General Synthesis of Ynamides and Alkynylphosphonates

    Jouvin, K.; Heimburger, J.; Evano, G. Chem. Sci. 2012, 3, 756-760.

    59- Copper-Catalyzed Coupling of 1,1-Dibromo-1-alkenes with Phenols: A General, Modular, and

    Efficient Synthesis of Ynol Ethers, Bromo Enol Ethers, and Ketene Acetals

    Jouvin, K.; Bayle, A.; Legrand, F.; Evano, G. Org. Lett. 2012, 14, 1652-1655.

  • 12

    60- Oxidative Alkynylation of Imines with Alkynylcopper Reagents: A Straightforward and Practical

    Entry to Ynimines

    Laouiti, A.; Jouvin, K.; Rammah, M. M.; Rammah, M. B.; Evano, G. Synthesis 2012, 44, 1491-1500.

    Numro spcial Copper in Organic Synthesis.

    61- Stereoselective Hydrofluorination of Ynamides: a Straightforward Synthesis of Novel -

    Fluoroenamides

    Compain, G.; Jouvin, K.; Martin-Mingot, A.; Evano, G.; Marrot, J.; Thibaudeau, S. Chem. Commun.

    2012, 48, 5196-5198.

    62- De Novo Synthesis of 1,4-Dihydropyridines and Pyridines

    Gati, W.; Rammah, M. M.; Rammah, M. B.; Couty, F.; Evano, G. J. Am. Chem. Soc. 2012, 134,

    9078-9081 (repris dans Synfacts, 2012, 8, 900).

    63- Copper-Mediated Selective Cross-Coupling of 1,1-Dibromo-1-alkenes and Heteronucleophiles:

    Development of General Routes to Heterosubtituted Alkynes and Alkenes

    Jouvin, K.; Coste, A.; Bayle, A.; Legrand, F.; Karthikeyan, G.; Tadiparthi, K.; Evano, G.

    Organometallics 2012, 31, 7933-7947. Numro spcial "Copper Organometallic Chemistry".

    64- Intramolecular Carbolithiation of N-Allyl-ynamides: an Efficient Entry to 1,4-Dihydropyridines and

    Pyridines - Application to a Formal Synthesis of Sarizotan

    Gati, W.; Rammah, M. M.; Rammah, M. B.; Evano, G. Beilstein J. Org. Chem. 2012, 8, 2214-2222.

    Srie thmatique "Carbometallation Chemistry".

    65- General Amination Reactions for the Synthesis of Ynamides

    Evano, G.; Jouvin, K.; Coste, A. Synthesis 2013, 45, 17-26.

    66- Expanding the Oxidative Chemistry of Organocopper Reagents: Facile Oxidative Cross-Coupling

    of Copper Acetylides with Arylboronic Acids

    Verna, F.; Guissart, C.; Pous, J.; Evano, G. Monatsh. Chem. 2013, sous presse, DOI :

    10.1007/s00706-012-0896-0. Numro spcial "Young Investigators"