puskaramula

8/7/2019 puskaramula

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INTRODUCTION

Controversy on identity of Puskaramoola is as

old as ayurvedic literature.

Introduced by Acharya Charaka

From the word “Pusan” the plant is named.

Inula racemosa Hook.

Asteraceae

4/8/11 22Pushkaramoola



HISTORY

In Agnipurana, puskara is described as verity

of Kusta

Familiar to the country by name Puskara

Desa PUSKARAMOOLA

Puskar of Rajastana (a pilgrimage place)




SYNONYMS

Puskaramula

Padmapatra

Kasmira

Kustabeda

Dhira

Padma4/8/11 44Pushkaramoola



VERNACULAR NAMES

Kannada: Pushkaramoola

English: Elicampane

Hindi: Pushkarmul

Marati: Pushkarmul

Malayalam: Puskkaramulam




CLASSICALCLASSIFICATION

Charaka: Swasahara, Hikkanigrahana

Susruta: Phalavarga

Vagbhata: Hidmanigrahana (A.H)

Svasashamaka (A.S)




Conti…

Bhavaprakasha: Haritakyadi varga

Rajanighantu: Pippali varga

Kaiyadeva Nighantu: Oushadi varga

Dhanvantari Nighantu: Guduchyadi varga

Adarsha Nighantu: Sahadevyadi varga




DISTRIBUTION

At temperate and alpine Western

Himalayas between 5,000-14,000 ft

altitude. Found under cultivation at

Garhwal and other places.




MORPHOLOGY

Tall stout herb

Stem: rough, groved

Leaves: Leathery, Rough

above, densely hairy

beneath, crenate

Basal leaves: long stalked,

elliptic-lance-shaped.

Stem leaves: oblong half 4/8/11 99Pushkaramoola

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Conti…

Flowers: in heads/ racemes,

very, large 3.8-5cm diameter. Outer

bracts broad, tips triangular, bent back,

inner bracts linear, sharp pointed.

Fruits: Achene, 4mm long, slender,

hairless, pappus 8mm. long, reddish.

4/8/11 Pushkaramoola 1010



CHEMICALCOMPOSITION

Alatolactone, isoalatolactone,

inunolide, dihydroisoalatolactone, β-

sitosterol, D-mannitol, dihydroinnolide,

neo-alantolactone, alatodiene, etc




PHARMACODYNAMICS

Rasa: Tikta, Katu

Guna: Laghu, Ruksha

Virya: Usna

Vipaka: katu

Karma: Kaphavatashamaka




PROPERTIES ANDACTION

Swasahara, Kaphahara,

Hikkanigrahana, Hrudya, Mutrajanaka,

Vajikarana, Garbhashayottejaka,

Medohara, Sothahara, Jantughna,

Vedanasthapana, Jantughna.




Rogaghanata

Swasa, Kasa, Hikka, Parsvashoola,

Hrutshoola, Hrutroga, Mutrakruchra,

Rajoroda, Kastarthava, Klaibya, Jvara

(VK), Pratishyaya, Medoroga,

Dourbalya, Pandu, Amavata.

4/8/11 Pushkaramoola 1414



THERAPEUTIC USES

Pushkaramula churna with madhu

Hrutshula, swasa, kasa

Pushkaramula Churna+Dashamula

kwatha swasa, kasa, urahshula,

hrushula




SUBSTITUTES &ADULTRATIONS

30% Adulteration is seen in market samples,

Adulterated with root of Inula royleane .DC

Saussurea lappa & Iris germanica

2 parts of Kusta in place of Pushkaramoola.




CONTRAVERSY

Based on name

– Pushkara

– Puskar– Pusan

Kusta beda

Iris germanica

Inula royleane DC




RESEARCH PROFILE

I. Racemosa extract decreses serumglucose level in dexamethasone

induced hyperglycemic mice

Decreased plasme glucose & insulin

levels in adrenaline hyperglycemic rats

Alcohol extract of root lowered blood

glucose and enhanced liver glycogen4/8/11 1818Pushkaramoola



Conti…In human study, root extract in case of

angina pectoris showed beneficialeffect

Alcoholic extract of root showed

marked protection against thebranchospasm in guinea pigs

Alantolactone isolated from the root

showed anti-inflammatory and hepatoprotective in albino rats

Essential oil of root exhibited anti-

fungal and anti-bacterial activity4/8/11 Pushkaramoola 1919



QUALITY STANDARDS

Foreign matter: not more than 1%

Ash value: Not more than 4.8%

Acid insoluble ash: Not more than 0.57%

Alcohol extract: Not less than 25%

Aqueous extract: Not less than 15%




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