QUALITY OF LIFE THROUGH QUALITY

OF INFORMATION

Studies in Health Technology and

Informatics

This book series was started in 1990 to promote research conducted under the auspices of the EC

programmes’ Advanced Informatics in Medicine (AIM) and Biomedical and Health Research

(BHR) bioengineering branch. A driving aspect of international health informatics is that

telecommunication technology, rehabilitative technology, intelligent home technology and many

other components are moving together and form one integrated world of information and

communication media. The series has been accepted by MEDLINE/PubMed, SciVerse Scopus,

EMCare, Book Citation Index – Science and Thomson Reuters’ Conference Proceedings Citation

Index.

Series Editors:

Dr. O. Bodenreider, Dr. J.P. Christensen, Prof. G. de Moor, Prof. A. Famili, Dr. U. Fors,

Prof. A. Hasman, Prof. E.J.S. Hovenga, Prof. L. Hunter, Dr. I. Iakovidis, Dr. Z. Kolitsi,

Mr. O. Le Dour, Dr. A. Lymberis, Prof. J. Mantas, Prof. M.A. Musen, Prof. P.F. Niederer,

Prof. A. Pedotti, Prof. O. Rienhoff, Prof. F.H. Roger France, Dr. N. Rossing,

Prof. N. Saranummi, Dr. E.R. Siegel, Prof. T. Solomonides and Dr. P. Wilson

Volume 180

Recently published in this series

Vol. 179. M. García-Rojo, B. Blobel and A. Laurinavicius (Eds.), Perspectives on Digital

Pathology – Results of the COST Action IC0604 EURO-TELEPATH

Vol. 178. A.J. Maeder and F.J. Martin-Sanchez (Eds.), Health Informatics: Building a

Healthcare Future Through Trusted Information – Selected Papers from the 20th

Australian National Health Informatics Conference (HIC 2012)

Vol. 177. B. Blobel, P. Pharow and F. Sousa (Eds.), pHealth 2012 – Proceedings of the 9th

International Conference on Wearable Micro and Nano Technologies for Personalized

Health

Vol. 176. T. Kotwicki and T.B. Grivas (Eds.), Research into Spinal Deformities 8

Vol. 175. S. Gesing, T. Glatard, J. Krüger, S.D. Olabarriaga, T. Solomonides, J.C. Silverstein,

J. Montagnat, A. Gaignard and D. Krefting (Eds.), HealthGrid Applications and

Technologies Meet Science Gateways for Life Sciences

Vol. 174. B. Blobel, R. Engelbrecht and M.A. Shifrin (Eds.), Large Scale Projects in eHealth –

Partnership in Modernization – Proceedings of the EFMI Special Topic Conference,

18–20 April 2012, Moscow, Russia

Vol. 173. J.D. Westwood, S.W. Westwood, L. Felländer-Tsai, R.S. Haluck, R.A. Robb,

S. Senger and K.G. Vosburgh (Eds.), Medicine Meets Virtual Reality 19 – NextMed

Vol. 172. Y. Quintana, A. Van Kirk Villalobos and D. May (Eds.), Advancing Cancer

Education and Healthy Living in Our Communities – Putting Visions and Innovations

into Action – Selected Papers from the Cure4Kids® Global Summit 2011

ISSN 0926-9630 (print)

ISSN 1879-8365 (online)

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© 2012 European Federation for Medical Informatics and IOS Press.

All rights reserved. No part of this book may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means, without prior written permission from the publisher.

ISBN 978-1-61499-100-7 (print) ISBN 978-1-61499-101-4 (online) Library of Congress Control Number: 2012945494

Publisher

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PRINTED IN THE NETHERLANDS

Preface

The theme of MIE2012 is ‘Quality of Life through Quality of Information’. The impor-

tance of Information towards Quality of Health Care and Quality of Life is highlighted

across the current proceedings. The 24th Medical Informatics in Europe Conference

(MIE2012) has been organised by the European Federation for Medical Informatics

(EFMI) with the collaboration of the Italian Medical Informatics Association (AIIM)

and the Italian e-health Community, and takes place in the historical city of Pisa, Italy

from 26th to 29th of August, 2012.

EFMI is a federation of national medical informatics associations from 32 Euro-

pean countries, and its purpose is to develop and disseminate knowledge and expertise

in the field of biomedical and health informatics. Besides the national associations, the

working groups, which include experts in specialist fields ranging from electronic pa-

tient records, medical imaging, and evaluation to nursing and rehabilitation, are the

main channel through which new knowledge and ideas are developed and disseminated.

Because EFMI understands the role which application and implementation plays, a

third pillar has been introduced to the federation, that of the Institutional Members,

such as industries, academic institutions and organisations.

The conference is being held in Pisa, a city well known not only for its famous

leaning tower, but also as the birthplace of Galileo Galilei, who some consider to be the

father of modern science. He was responsible for introducing the notion of experimen-

tal proof into scientific research. It is this approach which is, without any doubt, crucial

to our research in medical informatics. We need evidence before we can apply our

knowledge to health care; evidence-based medicine needs quality information in order

to lead to quality of health, and thus to quality of life.

The conference focuses on the role of e-health in pursuing benefits in terms of

quality of life for patients, health-care personnel, citizens and society. The topic can be

analysed from many points of view, and MIE2012 provides a unique platform for the

fruitful exchange of ideas and experiences among the actors and stakeholders of ICT

supported healthcare. Both methodologies and examples of applications form the basis

for the discussion, and all of us will learn, not only from success stories in the field, but

also from failures. The opinion and experiences of the designers and planners, as well

as those of users, are of great importance when the target is the global improvement of

quality of life, at both personal and public level. For this reason we encourage health

professionals, policy makers and also patients and citizens’ associations to take an ac-

tive part in the conference and share their knowledge.

The present volume incorporates contributions related to the latest achievements in

biomedical and health informatics in terms of major challenges such as interoperability,

collaboration, coordination, and increasingly, patient oriented health care at the most

appropriate level of care. The papers also provide new perspectives for the future of

biomedical and health informatics, critical appraisals of strategies for user involvement,

insights for design, deployment, and sustainable use of electronic health records, stan-

dards, social software, citizen centred e-health, and new challenges in rehabilitation

Quality of Life through Quality of InformationJ. Mantas et al. (Eds.)IOS Press, 2012© 2012 European Federation for Medical Informatics and IOS Press. All rights reserved.

v

and social care informatics, where health professionals collaborate in teams with col-

leagues and with their patients.

MIE2012 also introduces the ‘Village of the Future’; a vibrant agora where na-

tional, regional and European projects, as well as other initiatives, present, demonstrate,

discuss and share ideas and innovations in the ‘eLounge’, creating new coalitions for

the future. The village provides an opportunity to get involved in presentations, demon-

strations, and living poster and collaborative sessions. The village is open to all ‘citi-

zens’, with a focus on the younger generation, who can present new initiatives and re-

sults. In particular, presentations will be based on technologies such as the semantic

web, social media and web 2.0/3.0, which contribute to new ways of delivering health-

care and facilitating a higher quality of life for citizens, patients and health profession-

als alike. The presentations form part of the electronic version of the proceedings, and

are not included in the current volume.

The Scientific Programme Committee of MIE2012 received 449 submissions. The

selection process presented a major challenge for the SPC. Almost all submissions

were reviewed by three reviewers. The reviews were accompanied by suggestions and

advice for possible improvements to the contribution. In case of conflicting opinions,

the SPC appointed additional reviewers. We are indebted to the 205 colleagues who

volunteered their time and energy to be involved in this peer review processes, which

necessitated 1,077 individual reviews. The reviewers are listed in the appendix as a

token of our appreciation for their effort and dedication.

The programme for MIE2012 consists of 206 oral presentations of full papers,

48 posters, 25 short communication oral presentations, 26 short communication posters,

11 workshops, 2 EFMI WG workshops, 6 tutorials, and 2 panels. It is encouraging that

so many of the submissions are from young researchers, and we are pleased that

MIE2012 provides an arena where they can begin to exchange their ideas and findings

with their peers. Furthermore, MIE2012 hosts an application oriented track, the ‘Vil-

lage of the Future’, where EFMI institutional members and corporate affiliates can dis-

cuss pressing issues and innovations headed for the market, and where the latter will

also be demonstrated.

Most of the topics presented at MIE2012 are interdisciplinary in nature and of in-

terest to a variety of professionals: physicians, nurses, and allied health providers,

health informaticians, engineers, academics and representatives from industry and con-

sultancy in the various fields. This European conference commands an international

audience, gathering participants from most parts of the world. This is reflected by the

nationalities of the 1,016 contributing authors, originating from 43 countries in Europe,

the Middle East, Asia and Africa, as well as South and North America.

Conference proceedings consist of a printed version and an electronic version, and

are considered to be an integral part of MIE2012. The printed version includes full pa-

pers accepted for presentation as well as posters, and all are indexed in Medline. The

CD version of the proceedings includes the full papers, posters, short communications,

workshops, tutorials, panels, and a synopsis of the ‘Village of the Future’. The CD is an

EFMI publication, which will also be available online at www.EFMI.org after a period

agreed with the publisher.

We are grateful to the colleagues who served as members of the executive SPC,

and to the affiliate, Dr. Dimitrios Zikos. We would also like to express our thanks to

Drs. Jacob Hofdijk and Dr. Christian Lovis for coordinating the ‘Village of the Future’.

vi

Thanks also to Professor Jana Zvarova for chairing the subcommittee for workshop and

panel selection. Finally, we take this opportunity to thank the members of the award

committees for the Peter Reichertz Prize, awarded for the best paper by a young scien-

tist; the Rolf Hansen Prize for the best paper on a clinical information system; and the

poster prize for the best poster.

John Mantas

Stig Kjær Andersen

Maria Cristina Mazzoleni

Bernd Blobel

Silvana Quaglini

Anne Moen

Pisa, 25/06/2012

vii

Reviewers for MIE2012

Abidi, Samina

Abidi, Syed Sibte Raza

Adams, Samantha

Akbasoglu (Kaymakoglu), Beyza

Alpay, Laurence

Alsafadi, Yasser

Anguita, Alberto

Atreja, Ashish

Auma, Kennedy

Balbinot, Alexandre

Bamidis, Panagiotis

Barbosa, Sayonara

Bellika, Johan Gustav

Ben Said, Mohamed

Bernad, Elena

Beuscart, Regis

Beuscart-Zephir, Marie-Catherine

Borycki, Elizabeth

Boye, Niels

Bratan, Tanja

Breil, Bernhard

Bringay, Sandra

Brochhausen, Mathias

Brooks, Ian

Bygholm, Ann

Cabitza, Federico

Ceusters, Werner

Chae, Young Moon

Cheshire, Paul

Chronaki, Catherine

Cimino, James

Costa, Carlos

Courteille, Olivier

Cummings, Elizabeth

Curk, Tomaz

Daskalakis, Stylianos

Day, Karen

de Bruijn, Berry

De Clercq, Etienne

de Keizer, Nicolette

de la Calle, Guillermo

de la Harpe, Retha

Deserno, né Lehmann, Thomas M.

Dexheimer, Judith

Dias, Andre

Donaldson, Paul

Douali, Nassim

Eccher, Claudio

Effken, Judith

Eisenstein, Eric

Elberg, Pia

Epping, Paul

Fagan, Lawrence

Feria, Rommel

Fernandez-Breis, Jesualdo Tomas

Fioriglio, Gianluigi

Focsa, Mircea

Forkert, Nils Daniel

Fox, Scott

Fritz, Fleur

Frize, Monique

Fuchsberger, Christian

Gamberger, Dragan

Garde, Sebastian

Gardner, Reed

Georg, Gersende

Georgiou, Andrew

Giacomini, Mauro

Gibaud, bernard

Grabar, Natalia

Grain, Heather

Grandison, Tyrone

Hackl, Werner O.

Hagglund, Maria

Hains, Isla

Hammond, Ed

Hanmer, Lyn

Hansen, David

Hartvigsen, Gunnar

Haskell, Robert

Haux, Reinhold

Heinzl, Harald

Héja, Gergely

Holzmüller-Laue, Silke

Hristovski, Dimitar

Hsueh, Pei-Yun Sabrina

ix

Huser, Vojtech

Iancu, Miron

Ingenerf, Josef

Iriso, Santiago

James, Andrew

Jao, Chiang

Jaspers, Monique

Jones, Josette

Juhola, Martti

Kaiser, Katharina

Karanikolas, Nikitas

Karopka, Thomas

Katt, Basel

Kindler, Hauke

Klein, Gunnar O.

Knaup, Petra

Koufi, Vassiliki

Koutkias, Vassilis

Kusnierczyk, Waclaw

Lærum, Hallvard

Laforest, Frederique

Lahtela, Antti

Landmark, Andreas D.

Layzell, Brian

Lim Choi Keung, Sarah

Lippert, Søren

Lopez, Diego

Lovis, Christian

Lungeanu, Diana

Magrabi, Farah

Majeed, Raphael W.

Mayer, Miguel Angel

McClay, James

Mohd Yusof, Maryati

Mohyuddin, Mohyuddin

Montani, Stefania

Mueller, Henning

Müller, Marcel

Müller, Thomas

Murray, Peter

Muteba Ayumba, Eustache

Mykkänen, Juha

Niggemann, Joerg

Nøhr, Christian

Oemig, Frank

Oliveira, Jose Luis

Onken, Michael

Orel, Andrej

Otero, Paula

Pape-Haugaard, Louise

Parry, Dave

Pearl, Adrian

Peek, Niels

Pelayo, Sylvia

Peleg, Mor

Petkovic, Milan

Petrovecki, Mladen

Portet, François

Portinale, Luigi

Protti, Denis

Punys, Vytenis

Purnat, Tina D.

Razavi, Amir-Reza

Richards, Janise

Rindflesch, Thomas

Roberts, Jean

Roderer, Nancy

Rognoni, Carla

Röhrig, Rainer

Romacker, Martin

Rosenbeck, Kirstine

Rossing, Niels

Ruotsalainen, Pekka

Saboor, Samrend

Sacchi, Lucia

Saliez, Etienne

Santos, Raquel

Sara, Antony

Schabetsberger, Thomas

Schmidt, Rainer

Sedlmayr, Martin

Seroussi, Brigitte

Shahsavar, Nosrat

Shaw, Nicola (Nikki)

Showell, Chris

Silveira, Denise

Skrøvseth, Stein Olav

Smalheiser, Neil

Staemmler, Martin

Stausberg, Jürgen

Stenzhorn, Holger

Stern, Milton

Stoicu-Tivadar, Lacramioara

Supek, Selma

Talmon, Jan

ten Teije, Annette

Tirmizi, Suha

Toyoda, Shuichi

x

Tsiknakis, Manolis

Tusch, Guenter

van Engen-Verheul, Mariëtte

Vimarlund, Vivian

Vincent, Doug

Wang, Dongwen

Weltner, János

Welzer, Tatjana

Wilbacher, Ingrid

Witte, Herbert

Wolf, Klaus-Hendrik

Woolman, Paul

Zai, Adrian

Zary, Nabil

Zayim, Neşe

Zhang, Songmao

Zikos, Dimitris

xi

Contents

Preface v

John Mantas, Stig Kjær Andersen, Maria Cristina Mazzoleni, Bernd Blobel, Silvana Quaglini and Anne Moen

Reviewers for MIE2012 ix

Keynotes

Challenges of the e-Health Curricular Education in Bio-Medical Engineering

and in Medicine 3

Francesco Pinciroli, Stefano Bonacina, Sara Marceglia, Simona Ferrante and Luca Mazzola

Personal Health Records 9

Finn Kensing Enhancing Service Delivering, Improving Quality of Life, Preserving

Independence Through Assistive Technology 14

Roberta Annicchiarico The Future of Biomedical Informatics: A Perspective from Academia 19

Edward H. Shortliffe Improving Quality of Life Through eHealth – The Patient Perspective 25

Sabine Koch

Methodologies for Information Quality

Conceptual Modeling for Prospective Health Technology Assessment 33

Marion Gantner-Bär, Anatoli Djanatliev, Hans-Ulrich Prokosch and Martin Sedlmayr

Data Definition Ontology for Clinical Data Integration and Querying 38

Ariane Assele Kama, Audi Primadhanty, Rémy Choquet, Douglas Teodoro, Frank Enders, Catherine Duclos and Marie-Christine Jaulent

Migration Path for Structured Documentation Systems Including Standardized

Medical Device Data 43

Ann-Kristin Kock, Josef Ingenerf, Stoyan Halkaliev and Heinz Handels Quality Requirements for EHR Archetypes 48

Dipak Kalra, Archana Tapuria, Tony Austin and Georges De Moor Using Archetypes for Defining CDA Templates 53

David Moner, Alberto Moreno, José A. Maldonado, Montserrat Robles and Carlos Parra

Using Enterprise Ontology for Improving Emergency Management in Hospitals 58

David Galego Dias, Luís Velez Lapão and Miguel Mira da Silva

A ClaML-Based Interface for the Import of Monohierarchical Classifications 63

Sylvie Mn Ngouongo and Jürgen Stausberg

xiii

An Information Artifact Ontology Perspective on Data Collections and

Associated Representational Artifacts 68

Werner Ceusters Automatic Generation of MedDRA Terms Groupings Using an Ontology 73

Gunnar Declerck, Cédric Bousquet and Marie-Christine Jaulent Formal Specification of an Ontology-Based Service for EHR Interoperability 78

Carolina González, Bernd G.M.E. Blobel and Diego M. López Mapping SNOMED CT to ICD-10 83

Kathy Giannangelo and Jane Millar Rare Diseases Knowledge Management: The Contribution of Proximity

Measurements in OntoOrpha and OMIM 88

X. Aimé, J. Charlet, F. Furst, P. Kuntz, F. Trichet and F. Dhombres Design of an Original Interface That Facilitates the Use of Clinical Practice

Guidelines of Infection by Physicians in Primary Care 93

Rosy Tsopra, Jean-Baptiste Lamy, Alain Venot and Catherine Duclos Knowledge Representation for Fuzzy Inference Aided Medical Image

Interpretation 98

Norbert Gal and Vasile Stoicu-Tivadar MRI Image Artifact Ontology: A Proposed Method for Improved Recognition 103

Jeremy Lasbleiz, John Morelli, Nicolas Schnel, Anita Burgun, Régis Duvauferrier and Hervé Saint Jalmes

Ontology Driven Decision Support Systems for Medical Diagnosis 108

Valéry Donfack Guefack, Valérie Bertaud Gounot, Régis Duvauferrier, Annabel Bourde, John Morelli and Jérémy Lasbleiz

The Reproducibility of CLIF, a Method for Clinical Quality Indicator

Formalisation 113

Kathrin Dentler, Ronald Cornet, Annette ten Teije, Kristien Tytgat, Jean Klinkenbijl and Nicolette de Keizer

Virtual Medical Record Implementation for Enhancing Clinical Decision Support 118

Valentin-Sergiu Gomoi, Daniel Dragu and Vasile Stoicu-Tivadar An Application of Symbolic Dynamics for FHRV Assessment 123

Mario Cesarelli, Maria Romano, Paolo Bifulco, Gianni Improta and Gianni D’Addio

Automated Versus Interactive Spectral Analysis of Heart Rate Variability

from 24-Hour Holter Recordings in Heart Failure Patients 128

Roberto Maestri, Maria Teresa La Rovere and Gian Domenico Pinna Probabilistic Graphical Models for Effective Connectivity Extraction in the

Brain Using fMRI Data 133

Mohammad Ali Safari and Majid Mohammadbeigi Scale-Space Methods for Live Processing of Sensor Data 138

Stein Olav Skrøvseth, André Dias, Lukas Gorzelniak, Fred Godtliebsen and Alexander Horsch

Segmentation of Crohn, Lymphangiectasia, Xanthoma, Lymphoid Hyperplasia

and Stenosis Diseases in WCE 143

Omid Haji-Maghsoudi, A. Talebpour, H. Soltanian-Zadeh and N. Haji-Maghsoodi

xiv

Generation of a Probabilistic Arterial Cerebrovascular Atlas Derived from 700

Time-of-Flight MRA Datasets 148

Nils Daniel Forkert, Santiago Suniaga, Jens Fiehler, Heike Wersching, Stefan Knecht and Andre Kemmling

Customization of Biomedical Terminologies 153

Julien Homo, Laëtitia Dupuch, Allel Benbrahim, Natalia Grabar and Marie Dupuch

IRMA Code II: Unique Annotation of Medical Images for Access and Retrieval 159

Tim-Christian Piesch, Henning Müller, Christiane K. Kuhl and Thomas M. Deserno

Method for Mapping the French CCAM Terminology to the UMLS

Metathesaurus 164

Cédric Bousquet, Julien Souvignet, Tayeb Merabti, Eric Sadou, Béatrice Trombert and Jean-Marie Rodrigues

Semantic Relations of Binary Compounds Annotated with SNOMED CT 169

Dimitrios Kokkinakis The Issue of Building Generative Terminologies for Automatic Medical Data

Aggregation 174

Ihssen Belhadj, Jêrome Nobecourt, Sylvie Despres and Christian Jacquelinet

Towards a Bilingual Alzheimer’s Disease Terminology Acquisition Using

a Parallel Corpus 179

Khadim Drame, Gayo Diallo and Fleur Mougin An Ontological Approach to Manage and Harmonize Document Types 184

Frank Oemig and Bernd Blobel Patient Support ICT Tool for Hypertension Monitoring 189

Morten Algy Bonderup, Stine Veje Hangaard, Pernille Heyckendorff Lilholt, Mette Dencker Johansen and Ole K. Hejlesen

RAVEL: Retrieval and Visualization in ELectronic Health Records 194

Frantz Thiessard, Fleur Mougin, Gayo Diallo, Vianney Jouhet, Sébastien Cossin, Nicolas Garcelon, Boris Campillo, Wassim Jouini, Julien Grosjean, Philippe Massari, Nicolas Griffon, Marie Dupuch, Fayssal Tayalati, Edwige Dugas, Antonio Balvet, Natalia Grabar, Suzanne Pereira, Bruno Frandji, Stefan Darmoni and Marc Cuggia

Standard Based Multiclient Medical Data Visualization 199

Georgy Kopanitsa An Advanced Search Engine for Patent Analytics in Medicinal Chemistry 204

Emilie Pasche, Julien Gobeill, Douglas Teodoro, Arnaud Gaudinat, Dina Vishnyakova, Christian Lovis and Patrick Ruch

Classification and Prioritization of Biomedical Literature for the Comparative

Toxicogenomics Database 210

Dina Vishnyakova, Emilie Pasche, Julien Gobeill, Arnaud Gaudinat, Christian Lovis and Patrick Ruch

CliniQA: Highly Reliable Clinical Question Answering System 215

Yuan Ni, Huijia Zhu, Peng Cai, Lei Zhang, Zhaoming Qui and Feng Cao Development and Representation of Health Indicators with Thematic Maps 220

Simona Dalle Carbonare, Carlo Cerra and Riccardo Bellazzi

xv

Efficient Medical Information Retrieval in Encrypted Electronic Health Records 225

Cédric Pruski and François Wisniewski The Use of Linked Registries to Assess Long-Term Mortality of ICU Patients 230

Sylvia Brinkman, Evert de Jonge, Ameen Abu-Hanna, Dylan W. de Lange and Nicolette F. de Keizer

Grouping the Pharmacovigilance Terms with a Hybrid Approach 235

Marie Dupuch, Laëtitia Dupuch, Amandine Perinet, Thierry Hamon and Natalia Grabar

Information Extraction from SMS Text Related to a Reminder Service

for Outpatients 240

Stefania Rubrichi, Stéphanie Eku Ndam, Andrea Battistotti and Silvana Quaglini

Inventory of Tools for Dutch Clinical Language Processing 245

Ronald Cornet, Armand van Eldik and Nicolette de Keizer Linguistic Analysis of Large-Scale Medical Incident Reports for Patient Safety 250

Katsuhide Fujita, Masanori Akiyama, Keunsik Park, Etsuko (Nakagami) Yamaguchi and Hiroyuki Furukawa

Measuring Lexical Similarity Methods for Textual Mapping in Nursing

Diagnoses in Spanish and SNOMED-CT 255

Jorge Cruanes, M. Teresa Romá-Ferri and Elena Lloret A “Meta”-Perspective on “Bit Rot” of Biomedical Research Data 260

Frank Dickmann, Romanus Grütz and Otto Rienhoff A Semantic Approach for Digital Long-Term Preservation of Electronic Health

Documents 265

Stephan Kiefer, Michael Schäfer and Jochen Rauch Automated Realtime Data Import for the i2b2 Clinical Data Warehouse:

Introducing the HL7 ETL Cell 270

Raphael W. Majeed and Rainer Röhrig Coupling K-Nearest Neighbors with Logistic Regression in Case-Based

Reasoning 275

Boris Campillo-Gimenez, Sahar Bayat and Marc Cuggia Flexible Solution for Interoperable Cloud Healthcare Systems 280

Mihaela Marcella Vida, Oana Sorina Lupşe, Lăcrămioara Stoicu-Tivadar and Elena Bernad

TEDIS, Pervasive Developmental Disorder’ Patients Information System,

Preliminary Results 285

Mohamed Ben Said, Laurence Robel, Marie Pellegrin-Touati, Berangere Rousselot-Pailly, Bernard Golse, Jean Philippe Jais and Paul Landais

Characteristics of Patients at Risk for Adverse Drug Events: Designing for

Patient Safety and Decision Support 290

Elizabeth Borycki, Jeff Barnett, Susan Walisser, Paule Bellwood, Melissa Clarke and David Greig

Clinical Diagnosis Support System Based on Case Based Fuzzy Cognitive

Maps and Semantic Web 295

Nassim Douali, Jos De Roo and Marie-Christine Jaulent

xvi

Comparing Drools and Ontology Reasoning Approaches for Telecardiology

Decision Support 300

Pascal Van Hille, Julie Jacques, Julien Taillard, Arnaud Rosier, David Delerue, Anita Burgun and Olivier Dameron

Decision Support in Trauma Management: Predicting Potential Cases of

Ventilator Associated Pneumonia 305

Adrian Pearl and David Bar-Or Knowledge-Based Tacrolimus Therapy for Kidney Transplant Patients 310

Walter Seeling, Max Plischke and Christian Schuh Proposal of Diagnostic Process Model for Computer Based Diagnosis 315

Yasushi Matsumura, Toshihiro Takeda, Shiro Manabe, Hirokazu Saito, Kei Teramoto, Shigeki Kuwata and Naoki Mihara

Quality Through Evaluation

Challenges in Evaluating Telehealth Through RCT-The Problem of

Randomization 323

Urvashi Sharma, Julie Reed, Cathal Doyle and Derek Bell eHealth Indicators: Results of an Expert Workshop 328

Hannele Hyppönen, Elske Ammenwerth, Christian Nohr, Arild Faxvaag and Åke Walldius

eHealth Interoperability Evaluation Using a Maturity Model 333

Wded Guédria, Hanan Bouzid, Guido Bosh, Yannick Naudet and David Chen

Exploring a Methodology for eHealth Indicator Development 338

Hannele Hyppönen, Elske Ammenwerth and Nicolet de Keizer Population-Based Clinical Decision Support: A Clinical and

Economic Evaluation 343

Eric L. Eisenstein, Kevin J. Anstrom, Rex Edwards, Janese M. Willis, Jessica Simo and David F. Lobach

Quality Assurance and Effectiveness of the Medication Process Through

Tablet Computers? 348

Amanda Buus, Louise Nyvang, Sisse Heiden and Louise Pape-Haugaard A Framework for User Involvement and Context in the Design and

Development of Safe e-Health Systems 353

Andre Kushniruk and Paul Turner Analysis of Metrics for the Usability Evaluation of EHR Management Systems 358

Georgy Kopanitsa, Zhanna Tsvetkova and Hasan Veseli Low-Cost Rapid Usability Testing for Health Information Systems: Is It Worth

the Effort? 363

Tristin B. Baylis, Andre W. Kushniruk and Elizabeth M. Borycki Patient Safety-Oriented Usability Testing: A Pilot Study 368

Romaric Marcilly, Stephanie Bernonville, Costanza Riccioli and Marie-Catherine Beuscart-Zephir

The Role of Simulation in Clinical Information Systems Development 373

Sanne Jensen, Karen Marie Lyng and Christian Nøhr Using Video Observation to Gain Insight into Complex Clinical Work Practices 378

Anna Marie Balling Hostgaard and Pernille Bertelsen

xvii

ICU Nurses’ Evaluations of Integrated Information Displays on User

Satisfaction and Perceived Mental Workload 383

Sven H. Koch, Dwayne Westenskow, Charlene Weir, Jim Agutter, Maral Haar, Matthias Görges, David Liu and Nancy Staggers

Proactive Authenticated Notifications for Health Practitioners: Two Way

Human Computer Interaction Through Phone 388

Raphael W. Majeed, Mark R. Stöhr and Rainer Röhrig

Small Cause – Big Effect: Improvement in Interface Design Results in

Improved Data Quality – A Multicenter Crossover Study 393

Janko Ahlbrandt, Michael Henrich, Bernd A. Hartmann, Bettina B. Bundschuh, Julia Schwarz, Joachim Klasen and Rainer Röhrig

The Use and Usability of EPR Systems in Oncology 398

Thomas Poulter and Peter A. Bath Usability Evaluation of a Guideline Implementation System for Cardiac

Rehabilitation: Think Aloud Study 403

Mariëtte van Engen-Verheul, Linda Peute, Ellen Kilsdonk, Niels Peek and Monique Jaspers

Quality of Care Delivery Process

A Semantic Wiki for Editing and Sharing Decision Guidelines in Oncology 411

Thomas Meilender, Jean Lieber, Fabien Palomares, Gilles Herengt and Nicolas Jay

An Engine for Compliance Checking of Clinical Guidelines 416

Jing Mei, Haifeng Liu, Guotong Xie and Geetika T. Lakshmanan Application of the Logical Elements Rule Method for Formalization of

Clinical Rules: Case Study of ACOVE-NLI 421

Stephanie Medlock, Saeid Eslami, Dedan Opondo, Marjan Askari, Sophia de Rooij and Ameen Abu-Hanna

Clinical Guideline Representation in a CDS: A Human Information

Processing Method 427

Ellen Kilsdonk, Rinke Riezebos, Leontien Kremer, Linda Peute and Monique Jaspers

Computerized Clinical Guidelines: Current Status & Principles for Future

Research 432

Haridimos Kondylakis and Manolis Tsiknakis Ontology-Based Computerization of Acute Coronary Syndrome Clinical

Guideline for Decision Support in the Emergency Department 437

Mostafa Omaish, Samina Abidi and Syed Sibte Raza Abidi A Semiotic View on Paper and Mobile Care Data Quality 442

Retha De La Harpe Challenges and Issues of Geolocation in Clinical Environment 447

David-Zacharie Issom, Claire Hagry, Laetitia Wodia Mendo, Henry Seng, Frederic Ehrler and Christian Lovis

Empower the Patients with a Dialogue-Based Web Application 452

Charlotte D. Bjørnes, Elizabeth Cummings and Christian Nøhr From Clinical Requirement to Personalized Wellness Decision Support:

A Data-Driven Framework for Computer-Supported Guideline Refinement 457

Pei-Yun Hsueh, Ci-Wei Lan, Vincent Deng and Xinxin Zhu

xviii

Interoperability Design of Personal Health Information Import Service 462

Mika Tuomainen and Juha Mykkänen Using a Patient-Centered Approach for Health and Social Care Integration 467

Mikaela Poulymenopoulou, Despoina Papakonstantinou, Flora Malamateniou and George Vassilacopoulos

Accuracy of Clinical Data Entry when Using a Computerized Decision

Support System: A Case Study with OncoDoc2 472

Brigitte Séroussi, Brigitte Blaszka-Jaulerry, Laurent Zelek, Jean-Pierre Lefranc, Rosa Conforti, Jean-Philippe Spano, Alexandra Rousseau and Jacques Bouaud

Elicitating Patient Patterns of Physician Non-Compliance with Breast

Cancer Guidelines Using Formal Concept Analysis 477

Jacques Bouaud, Nizar Messai, Cédric Laouénan, France Mentré and Brigitte Séroussi

Evidence Based Electronic System to Ensure Quality of Care in Trauma Patients 482

Vasiliki Mpletsa, Ioannis Kaklamanos, Konstantinos Birbas and John Mantas

OpenEHR-Based Representation of Guideline Compliance Data Through

the Example of Stroke Clinical Practice Guidelines 487

Nadim Anani, Rong Chen, Tiago Prazeres Moreira and Sabine Koch Towards Collaborative Chronic Care Using a Clinical Guideline-Based

Decision Support System 492

Haifeng Liu, Jing Mei and Guotong Xie A Standardized Middleware as the Core of a Telemonitoring European Project 497

Fabio Vergari, Roberta Gazzarata, Francesco Morandi, Viola Parodi, Simone Naso, Alessandra Arezza, Tulio Salmon Cinotti and Mauro Giacomini

Dicoogle Mobile: A Medical Imaging Platform for Android 502

Carlos Viana-Ferreira, Daniel Ferreira, Frederico Valente, Eriksson Monteiro, Carlos Costa and José Luís Oliveira

Does Telecare Reduce the Number of Treatment Days? 507

Yuji Akematsu and Masatsugu Tsuji Establishing End-to-End Security in a Nationwide Network for Telecooperation 512

Martin Staemmler, Michael Walz, Gerald Weisser, Uwe Engelmann, Robert Weininger, Antonio Ernstberger and Johannes Sturm

Quality Through and for Research

A Loosely Coupled Framework for Terminology Controlled Distributed EHR

Search for Patient Cohort Identification in Clinical Research 519

Lei Zhao, Sarah N. Lim Choi Keung, Adel Taweel, Edward Tyler, Ire Ogunsina, James Rossiter, Brendan C. Delaney, Kevin A. Peterson, F.D. Richard Hobbs and Theodoros N. Arvanitis

Key-Linked On-Line Databases for Clinical Research 524

Thomas H. Müller Standardised Representation of Healthcare Information in Secondary Care

Research: A Central England Case Study 529

Sarah N. Lim Choi Keung, Ire Ogunsina, James Rossiter, Gavin Langford, Edward Tyler and Theodoros N. Arvanitis

xix

The Electronic Healthcare Record for Clinical Research (EHR4CR)

Information Model and Terminology 534

David Ouagne, Sajjad Hussain, Eric Sadou, Marie-Christine Jaulent and Christel Daniel

A DICOM Architecture for Clinicians and Researchers 539

Michael Onken Ophiucus: RDF-Based Visualization Tool for Health Simulation Models 544

Andrew Sutcliffe, Anya Okhmatovskaia, Arash Shaban-Nejad and David Buckeridge

Validation and Discovery of Genotype-Phenotype Associations in Chronic

Diseases Using Linked Data 549

Jyotishman Pathak, Richard Kiefer, Robert Freimuth and Christopher Chute

A Web-Based Tool for Patients Cohorts and Clinical Trials Management 554

P. Fraccaro and Mauro Giacomini Designing and Implementing a Biobanking IT Framework for Multiple

Research Scenarios 559

Hans-Ulrich Prokosch, Sebastian Mate, Jan Christoph, Andreas Beck, Felix Köpcke, Stefanie Stephan, Matthias W. Beckmann, Tilman Rau, Arndt Hartmann, Bernd Wullich, Bernhard Breil, Kai-Uwe Eckardt, Stephanie Titze, Jens K. Habermann, Josef Ingenerf, Michael Hackmann, Markus Ries, Thomas Bürkle and Thomas Ganslandt

Interoperability in Clinical Research: From Metadata Registries to

Semantically Annotated CDISC ODM 564

Philipp Bruland, Bernhard Breil, Fleur Fritz and Martin Dugas Requirements for Semantic Biobanks 569

André Q. Andrade, Markus Kreuzthaler, Janna Hastings, Maria Krestyaninova and Stefan Schulz

A Semantic Model for Multimodal Data Mining in Healthcare Information

Systems 574

Dimitris Iakovidis and Christos Smailis Assessing the Clinical Uses of Fuzzy Detection Results in the Automated

Detection of CVC-Related Infections: A Preliminary Report 579

Jeroen S. de Bruin, Alexander Blacky and Klaus-Peter Adlassnig Assessing the Feasibility of Data Mining Techniques for Early Liver

Cancer Detection 584

Mu-Hsing Kuo, Chang-Mao Hung, Jeff Barnett and Fabiola Pinheiro

Automatic Extracting of Patient-Related Attributes: Disease, Age, Gender

and Race 589

Huijia Zhu, Yuan Ni, Peng Cai, Zhaoming Qiu and Feng Cao Estimating Rheumatoid Arthritis Activity with Infrared Image Analysis 594

Monique Frize and Abiola Ogungbemile Fine-Grained Clinical Outcome Extraction and Polarity Classification 599

Peng Cai, Yuan Ni, Huijia Zhu and Feng Cao Evicase: An Evidence-Based Case Structuring Approach for Personalized

Healthcare 604

Boaz Carmeli, Paolo Casali, Anna Goldbraich, Abigail Goldsteen, Carmel Kent, Lisa Licitra, Paolo Locatelli, Nicola Restifo, Ruty Rinott, Elena Sini, Michele Torresani and Zeev Waks

xx

Reusable Data in Public Health Databases – Problems Encountered in Danish

Children’s Database 609

Anna Marie Høstgaard and Louise Pape-Haugaard Secondary Use of Clinical Data in Healthcare Providers – An Overview

on Research, Regulatory and Ethical Requirements 614

Matthias Wiesenauer, Christian Johner and Rainer Röhrig Standardizing Intensive Care Device Data to Enable Secondary Usages 619

Josef Ingenerf, Ann-Kristin Kock, Marcel Poelker, Konrad Seidl, Georg Zeplin, Stefan Mersmann and Heinz Handels

Why Is Clinical Information Not Reused? 624

Gert Galster

Supporting Decisions

Archetype Based Search in an IHE XDS Environment 631

Christoph Rinner, Michael Kohler, Gudrun Hübner-Bloder, Samrend Saboor, Elske Ammenwerth and Georg Duftschmid

Concepts for a Personal Health Record 636

Cândido Santos, Tiago Pedrosa, Carlos Costa and José Luis Oliveira

Enhancing the Many-to-Many Relations Across IHE Document Sharing

Communities 641

Luís S. Ribeiro, Carlos Costa and José Luís Oliveira Standardized EHR Interoperability – Preliminary Results of a German

Pilot Project Using the Archetype Methodology 646

Hasan Veseli, Georgy Kopanitsa and Hans Demski The FBE Development Project: Toward Flexible Electronic Standards-Based

Biopsycho-Social Individual Records 651

Lucilla Frattura, Andrea Simoncello, Giovanni Bassi, Andrea Soranzio, Stefano Terreni and Fulvio Sbroiavacca

An EMR Based Cancer Diary – Utilisation and Initial Usability Evaluation

of a New Cancer Data Visualization Tool 656

Markus Ries, Henriette Golcher, Hans-Ulrich Prokosch, Matthias W. Beckmann and Thomas Bürkle

Automatic Detection of Inconsistencies Between Free Text and Coded

Data in Sarcoma Discharge Letters 661

Ruty Rinott, Michele Torresani, Rossella Bertulli, Abigail Goldsteen, Paolo Casali, Boaz Carmeli and Noam Slonim

Fragmentation of Diabetes Treatment in Austria – An Indicator for the

Need for Shared Electronic Health Record Systems 667

Georg Duftschmid, Wolfgang Dorda, Gottfried Endel, Karl Fröschl, Walter Gall, Wilfried Grossmann and Milan Hronsky

Health Data Collecting and Sharing: Case Studies of Czech e-Health

Applications 672

Jana Zvárová, Lenka Lhotská, Libor Seidl and Karel Zvára Ontology-Based Reusable Clinical Document Template Production System 677

Sejin Nam, Sungin Lee, James G. Boram Kim and Hong-Gee Kim The Distributed Use of Electronic Emergency-Department Whiteboards 683

Morten Hertzum

xxi

A Data-Driven Living Review for Pharmacogenomic Decision Support in

Cancer Treatment 688

Gökhan Karakülah, Aslı Suner, Klaus-Peter Adlassnig and Matthias Samwald

Electronic Medication Ordering with Integrated Drug Database and Clinical

Decision Support System 693

Andreja Čufar, Anže Droljc and Andrej Orel Isolation of Patients with Vancomycin Resistant Enterococci (VRE): Efficacy

of an Electronic Alert System 698

Damian Borbolla, Vanina Taliercio, Bibiana Schachner, Ana Maria Gomez Saldano, Estela Salazar, Daniel Luna and Fernan Gonzalez Bernaldo De Quiros

Knowledge-Analytics Synergy in Clinical Decision Support 703

Noam Slonim, Boaz Carmeli, Abigail Goldsteen, Oliver Keller, Carmel Kent and Ruty Rinott

Quality of Data and Patients’ Safety

Indicators of Data Quality: Revision of a Guideline for Networked

Medical Research 711

Jürgen Stausberg, Ron Pritzkuleit, Carsten O. Schmidt, Thomas Schrader and Michael Nonnemacher

Relevance of Drug-Drug Interaction in the ICU – Perceptions of Intensivists

and Pharmacists 716

Marjan Askari, Saied Eslami, Mathijs Louws, Dave Dongelmans, Peter Wierenga, Rob Kuiper and Ameen Abu-Hanna

Organizing Data Quality Assessment of Shifting Biomedical Data 721

Carlos Sáez, Juan Martínez-Miranda, Montserrat Robles and Juan Miguel García-Gómez

Quality Assessment of Automatically Extracted Data from GPs’ EPR 726

Etienne De Clercq, Sarah Moreels, Viviane Van Casteren, Nathalie Bossuyt, Geert Goderis and Stefaan Bartholomeeusen

Safety of a Web-Based Insulin Titration System for Patients with Type 2

Diabetes Mellitus – Pilot Study 731

A.C.R. Simon, F. Holleman, W.T. Gude, J.B.L. Hoekstra and N. Peek The Role of Electronic Checklists – Case Study on MRI-Safety 736

Andreas Landmark, May-Britt Selnes, Elisabeth Larsen, Astrid Svensli, Linda Solum and Berit Brattheim

EHR and Data Protection Issues in Italy 741

Maria Gabriella Virone

Ontology Based Log Content Extraction Engine for a Posteriori Security

Control 746

Hanieh Azkia, Nora Cuppens-Boulahia, Frédéric Cuppens and Gouenou Coatrieux

Recognition and Privacy Preservation of Paper-Based Health Records 751

Stefan Fenz, Johannes Heurix and Thomas Neubauer

Towards Human-Centric Visual Access Control for Clinical Data

Management 756

Sascha Fahl, Marian Harbach and Matthew Smith

xxii

Watermarking as a Traceability Standard 761

Gouenou Coatrieux, Catherine Quantin and François-André Allaert A Statistics-Based Approach of Contextualization for Adverse Drug Events

Detection and Prevention 766

Emmanuel Chazard, Stéphanie Bernonville, Grégoire Ficheur and Régis Beuscart

Identifying Types and Causes of Errors in Mortality Data in a Clinical

Registry Using Multiple Information Systems 771

Antonie Koetsier, Niels Peek and Nicolette de Keizer Implementation of Computerized Physician Order Entry (CPOE) with Clinical

Decision Support (CDS) Features in Riyadh Hospitals to Improve Quality

of Information 776

Mariam S. Almutairi, Rana M. Alseghayyir, Anwar A. Al-Alshikh, Hayat M. Arafah and Mowafa S. Househ

Information-Based Sequential Selection of Clinical Tests in Risk Assessment 781

Naama Parush, Tal El-Hay, Michal Ozery-Flato, Ligita Ryliskyte, Zydrune Visockiene and Aleksandras Laucevicius

Using EHR Data for Monitoring and Promoting Patient Safety: Reviewing

the Evidence on Trigger Tools 786

Persephone Doupi

Added Value of Web-Based Services

Architectural Approach for Quality and Safety Aware HealthCare

Social Networks 793

Diego M. López, Bernd Blobel and Carolina González Human Rights Monitoring in Virtual Community 798

Christo El Morr Impact of the Social Networking Applications for Health Information

Management for Patients and Physicians 803

Tony Sahama, Jian Liang and Renato Iannella

Mobile Social Networking Health (MSNet-Health): Beyond the mHealth

Frontier 808

Mowafa Househ On the Support of Flexible Patient Privacy Policies in Social-Medical

Discovery 813

Haggai Roitman, Sivan Yogev, Yevgenia Tsimerman and Yardena Peres Technical Requirements of a Social Networking Platform for Senior Citizens 818

Hans Demski, Claudia Hildebrand, José López Bolós, Winfried Tiedge, Stefanie Wengel, Daire Ó. Broin and Ross Palmer

A Real-Time Disease Surveillance Architecture Using Social Networks 823

Mustafa Sofean and Matthew Smith Experiences in the Creation of an Electromyography Database to Help Hand

Amputated Persons 828

Manfredo Atzori, Arjan Gijsberts, Simone Heynen, Anne-Gabrielle Mittaz Hager, Claudio Castellimi, Barbara Caputo and Henning Müller

Exploring the Community Structure of a Diabetes Forum 833

André Dias, Taridzo Chomutare and Taxiarchis Botsis

xxiii

Leveraging Social Media for Preventive Care – A Gamification System

and Insights 838

Raymund J. Lin and Xinxin Zhu Online Health Information Search: What Struggles and Empowers the Users?

Results of an Online Survey 843

Natalia Pletneva, Alejandro Vargas, Konstantina Kalogianni and Célia Boyer

Finding Online Health-Related Information: Usability Issues of Health Portals 848

Nergis A. Gurel Koybasi and Kursat Cagiltay How Medical Doctors and Students Should Use Social Media: A Review

of the Main Guidelines for Proposing Practical Recommendations 853

Miguel Angel Mayer, Angela Leis, Alex Mayer and Alejandro Rodriguez-Gonzalez

Tracking Changes in Search Behaviour at a Health Web Site 858

Ann-Marie Eklund Trustworthiness and Relevance in Web-Based Clinical Question Answering 863

Sarah Cruchet, Célia Boyer and Lonneke van der Plas

Learn from Experiences and Critical Thinking

A Culture and Power Perspective on the Management of Health Information

Technology in Hospitals 871

Lone Stub Petersen and Pernille Bertelsen Economic Impact of a Nationwide Interoperable e-Health System Using

the PENG Evaluation Tool 876

L. Parv, J. Saluse, A. Aaviksoo, M. Tiik, R. Sepper and P. Ross How Should We Define eHealth, and Does the Definition Matter? 881

Chris Showell and Christian Nøhr Medical Device Software: A New Challenge 885

Daniela Luzi and Fabrizio Pecoraro The Intellectual Property Management for Data Sharing in a German Liver

Cancer Research Network 891

Shan He, Matthias Ganzinger and Petra Knaup The Nature of Unintended Benefits in Health Information Systems 896

Craig E. Kuziemsky, Elizabeth Borycki, Christian Nøhr and Elizabeth Cummings

Envisioning Electronic Health Record Systems as Change Management:

The Experience of an English Hospital Joining the National Programme

for Information Technology 901

Amirhossein Takian

Method for Modeling Social Care Processes for National Information

Exchange 906

Aki Miettinen, Juha Mykkänen and Maarit Laaksonen On the Attitudes of GPs Toward Novel Features of Their Next EPRs 911

Federico Cabitza Proposal of an Architecture for the National Integration of Electronic Health

Records: A Semi-Centralized Approach 917

Asma Al Jarullah and Samir El-Masri

xxiv

Uniforming Information Management in Finnish Social Welfare 922

Maarit Laaksonen, Jarmo Kärki and Erja Ailio

Quality Through Education

Assessment in Health Care Education – Modelling and Implementation

of a Computer Supported Scoring Process 929

Jayne Alfredsson, Patrick Plichart and Nabil Zary eHealth Education of Professionals in the Baltic Sea Area 934

Ann Bygholm, Julia Günther, Pernille Bertelsen and Christian Nøhr Is It Worth Investing in Online Continuous Education for Healthcare Staff? 939

M. Cristina Mazzoleni, Chiara Maugeri, Carla Rognoni, Alessio Cantoni and Marcello Imbriani

Nursing Informatics Competences Still Challenging Nurse Educators 944

Elina Rajalahti and Kaija Saranto Teaching Medicine with a Terminology/Ontology Portal 949

Julien Grosjean, Tayeb Merabti, Nicolas Griffon, Badisse Dahamna and Stéfan J. Darmoni

Criteria to Assess the Quality of Virtual Patients 954

Inga Hege, Nabil Zary and Andrzej A. Kononowicz

New Approaches to Linking Clinical Guidelines to Virtual Patients 958

Andrzej A. Kononowicz, Inga Hege, Paweł Krawczyk and Nabil Zary Recommendation of Standardized Health Learning Contents Using Archetypes

and Semantic Web Technologies 963

María del Carmen Legaz-García, Catalina Martínez-Costa, Marcos Menárguez-Tortosa and Jesualdo Tomás Fernández-Breis

SIScaR-GPU: Fast Simulation and Visualization of Intraoperative Scattered

Radiation to Support Radiation Protection Training 968

Markus Wagner, Klaus Dresing, Wolfram Ludwig, Christoph Alexander Ahrens and Oliver J. Bott

Towards a mLearning Training Solution to the Adoption of a CPOE System 973

Despoina Pakonstantinou, Mikaela Poulymenopoulou, Flora Malamateniou and George Vassilacopoulos

Virtual Patient Simulation: A Comparison of Two Approaches for Capacity

Building in Sub-Saharan Africa 978

Georges Bediang, Marc-André Raetzo and Antoine Geissbuhler

Quality Through Support

An Integration of Emergency Department Information and Ambulance

Systems 985

Nada Al-Harbi, Samir El-Masri and Basema Saddik Analyzing Primary Care Data to Characterize Inappropriate Emergency

Room Use 990

Justin St-Maurice and M.H. Kuo COCPIT: A Tool for Integrated Care Pathway Variance Analysis 995

John Ainsworth and Iain Buchan

xxv

Flexible Medical Image Management Using Service-Oriented Architecture 1000

Oded Shaham, Alex Melament, Yuval Barak-Corren, Igor Kostirev, Noam Shmueli and Yardena Peres

Measuring Health Care Process Quality with Software Quality Measures 1005

Özkan Yildiz and Onur Demirörs

Bringing Research to the Point of Care: Hypergenes Project Study 1010

Edward Vitkin, Hani Neuvirth-Telem, Boaz Carmeli, Amnon Shabo and Ariel Farkash

Do Worklists Work? A Quantitative Approach to the Assessment of an

Electronic Patient Record Function 1015

Petter Hurlen Log Analysis to Understand Medical Professionals’ Image Searching

Behaviour 1020

Theodora Tsikrika, Henning Müller and Charles E. Kahn Jr. Ontology-Supported Clinical Profiling for the Evaluation of Obesity and

Related Comorbidities 1025

Paolo L. Scala, Davide Di Pasquale, Daniele Tresoldi, Claudio L. Lafortuna, Giovanna Rizzo and Marco Padula

Texture Analysis Software: Integration with a Radiological Workstation 1030

Régis Duvauferrier, Joan Bezy, Valérie Bertaud, Grégoire Toussaint, John Morelli and Jeremy Lasbleiz

A Smartphone Application for Preventing Exercise-Induced Glycemic

Imbalances in Type 1 Diabetic Patients 1035

Omar Vuattolo, Maria Pia Francescato, Vincenzo Della Mea and Agostino Accardo

An Android-Enabled Mobile Framework for Ensuring Quality of Life

Through Patient-Centric Care 1040

Vassiliki Koufi, Flora Malamateniou and George Vassilacopoulos Model Driven Mobile Care for Patients with Type 1 Diabetes 1045

Stein Olav Skrøvseth, Eirik Årsand, Fred Godtliebsen and Ragnar M. Joakimsen

Personalized Adherence Activity Recognition via Model-Driven Sensor Data

Assessment 1050

Mark Hsiao, Pei-Yun Hsueh and Sreeram Ramakrishnan Achieving IT-Supported Standardized Nursing Documentation Through

Participatory Design 1055

Stine Loft Rasmussen, Karen Marie Lyng and Sanne Jensen Consistency of Nurses’ Daily Predictions of Survival in the Intensive Care 1060

Lilian Minne, Dave A. Dongelmans, E. de Jonge and Ameen Abuhanna Development of Pain Flowsheet Based on Electronic Nursing Record System 1065

JungMin Lee, YoungAh Kim, Hyunsoon Jung and Malsoon Song Electronic Nursing Documentation in a Paediatrics Hospital: Impact on

Quality of Care by Using OpenEHR, IHE and HL7 1070

Majda Oštir, Marinka Purkart, Anita Štih, Biljana Prinčič and Andrej Orel

ICNP Catalogues for Supporting Nursing Content in Electronic Health

Records 1075

Amy Coenen, Tae Youn Kim, Claudia C. Bartz, Kay Jansen and Nicholas Hardiker

xxvi

INCA – Individual Nomad Clinical Assistant – Supporting Nurses with

Mobile Devices 1079

Frederic Ehrler, Magali Walesa, Evelyne Sarrey, Rolf Wipfli and Christian Lovis

Posters

A System-Theoretical, Architecture-Based Approach to Ontology Management 1087

Bernd Blobel, Mathias Brochhausen, Carolina González, Diego M. Lopez and Frank Oemig

Characteristics of Health Interventions: A Systematic Analysis of the Austrian

Procedure Catalogue 1090

Sabrina B. Neururer and Karl-Peter Pfeiffer Describing the Sublanguage of Wound Care in an Adult ICU 1093

Riitta Danielsson-Ojala, Heljä Lundgren-Laine and Sanna Salanterä Developing a Patient Education Method – The e-Knowledge Test with

Feedback 1096

Mervi Siekkinen and Helena Leino-Kilpi Representing Clinical Communication Knowledge Through Database

Management System Integration 1099

Saif Khairat, Catherine Craven and Yang Gong Semantic Enrichment of Medical Forms – Semi-Autding of ODM-Elements

via Web Services 1102

Bernhard Breil, Andreas Watermann, Peter Haas, Philipp Dziuballe and Martin Dugas

Conducting Requirements Analyses for Research Using Routinely

Collected Health Data: A Model Driven Approach 1105

Simon de Lusignan, Josephine Cashman, Norman Poh, Georgios Michalakidis, Aaron Mason, Terry Desombre and Paul Krause

Classification of Ischaemic Episodes with ST/HR Diagrams 1108

Jana Faganeli Pucer, Janez Demšar and Matjaž Kukar Collaborative Development of Knowledge-Based Support Systems: A Case

Study 1111

Helena Lindgren, Patrik J. Winnberg and Chunli Yan Integration of Data Analysis Methods in Syndromic Surveillance Systems 1114

Dimitrios Zikos and Marianna Diomidous Statistical Disclosure Limitation of Health Data Based on Pk-Anonymity 1117

Eizen Kimura, Koji Chida, Dai Ikarashi, Koki Hamada and Ken Ishihara Ultradian Rhythms During Day and Night in Normal and COPD Subjects 1120

Agostino Accardo, Monica Cusenza, Alberto De Felice, Elisa Fornasa and Giovanni D’Addio

A Literature Overview and Comparison of Driving Impairing Condition

Assessment Approaches by Health Enabling Technologies 1123

Nina Reichwaldt, Susanne Maslak, Klaus-Hendrik Wolf and Reinhold Haux

CARDIO-i2b2: Integrating Arrhythmogenic Disease Data in i2b2 1126

Daniele Segagni, Valentina Tibollo, Arianna Dagliati, Carlo Napolitano, Silvia G. Priori and Riccardo Bellazzi

xxvii

Impact of Computerized Order Sets on Practitioner Performance 1129

Leila Ahmadian and Reza Khajouei IT as an Enabler of Sustainable Use of Data from Innovative Technical

Components for Assisted Living 1132

Petra Knaup and Lothar Schöpe IT Behind a Platform for Translational Cancer Research – Concept and

Objectives 1135

Michael Steffens, Gabriele Husmann, Mithat Koca, Martin Lablans, Martina Komor, Sylke Zeissig, Katharina Emrich, Christian Brandts, Hubert Serve, Maria Blettner and Frank Ückert

Psychological Evaluation of 24-Hour Home Nursing Care: Application

of an Analytic Hierarchy Process to Improve Quality of Life 1138

Takeo Shibata, Yoko Shimizu and Hiroko Wada A Clinical Research Analytics Toolkit for Cohort Study 1141

Yiqin Yu, Yu Zhu, Xingzhi Sun, Ying Tao, Shuo Zhang, Linhao Xu and Yue Pan

An Encapsulated R Application for the Guided Analysis of Genomic Data 1144

Matthias Ganzinger, Miriam Kesselmeier, Jasmin Fabian and Petra Knaup

First Experiences in Implementing a Software-Based Support for Patient

Recruitment at Heidelberg University Hospital 1147

Björn Schreiweis, Günter Grüber and Björn Bergh Medical Students and e-Health 1150

Mira Hercigonja-Szekeres, Vesna Ilakovac and Krešimir Šolić Multiple Disciplines Synergy Tools for Ph.D. Students of Biomedical

Informatics at Charles University in Prague 1153

Jana Zvarova, Stepan Svacina, Tatjana Dostalova, Michaela Seydlova and Karel Zvara

Translational Meta-Analysis Tool for Temporal Gene Expression Profiles 1156

Guenter Tusch and Olvi Tole Pluripotent Stem Cells in Mice 1159

Rainer Schmidt, Lena Scheubert, Mitja Lustrek, Dirk Repsilber and Georg Fuellen

Introducing a Composite Index of Information Quality for Medical Web Sites 1162

Federico Cabitza Concise Healthcare-Associated Infection Reporting and Benchmarking with

Minimal Staff Resources 1165

Walter Koller, Jeroen de Bruin, Alexander Blacky, Harald Mandl and Klaus-Peter Adlassnig

Developing an eLearning Tool Formalizing in YAWL the Guidelines Used

in a Transfusion Medicine Service 1168

Paola Russo, Miriam Piazza, Giorgio Leonardi, Layla Roncoroni, Carlo Russo, Salvatore Spadaro and Silvana Quaglini

e-Learning for Neurological Bladder Management 1171

Carla Rognoni, Gabriella Fizzotti, Caterina Pistarini and M. Cristina Mazzoleni

Patient Empowerment in the Process of Sickness Certificates 1174

Gunnar O. Klein and Kjell Andersson

xxviii

Patient Satisfaction in a Context-Aware Hospital Guidance System 1177

Eunhye Kim, Sooyoung Yoo, Hwang Hee, Hyunchul Park, Gunhee Kim and Sungdo Ha

A Special Query Tool in the Hospital Information System to Recognize

Patients and to Increase Patient Numbers for Clinical Trials 1180

Mithat Koca, Gabriele Husmann, Jürgen Jesgarz, Martin Overath, Christian Brandts and Hubert Serve

Design of a Computerized Provider Order Entry System for Ordering

of Chemotherapy 1182

SunHee Lee, KiHyuk Lee, Eun-Young Cho, Hee Hwang, KiDong Kim, Young-Jae Cho, JungEun Kim, Jae Hyuk Lee, Rong Min Baek and YoungSik Jeon

Development and Evaluation of an Expert System for the Diagnosis of Child

Autism 1185

Pashalina Lialiou, Dimitrios Zikos and John Mantas ICF Machine: A Web-Based System for Collection of ICF Data 1188

Vincenzo Della Mea and Valerio Fioresi ‘Onco Alerts’ to Support Acute Oncology Services 1191

Thomas Poulter and Peter A. Bath Promoting Generic Medication Prescribing by Order Interface Redesign:

Small Change, Large Impact 1194

Sameer Malhotra, Jessica S. Ancker, J. Travis Gossey, Curtis L. Cole, Rainu Kaushal and Adam D. Cheriff

Study of Iranian Breast Cancer Registration via Established Online System

During 2011 1197

Mohammad Zare, Abolfazl Rezaee, Sholeh Zakiani and Amir Zare Clinical Decision Support for Monitoring Drug-Drug-Interactions and

Potassium-Increasing Drug Combinations: Need for Specific Alerts 1200

Emmanuel Eschmann, Patrick E. Beeler, Vladimir Kaplan, Markus Schneemann, Gregor Zünd and Jürg Blaser

Decision Support System Based Semantic Web for Personalized Patient Care 1203

Nassim Douali, Jos De Roo and Marie-Christine Jaulent Development of an Electronic Nursing Records System Based on Information

Models and Clinical Practice Guidelines 1206

Hyeoun-Ae Park, Yul Ha Min, Eunjoo Jeon, Younglan Kim and Hyun-Young Km

Formative Usability Evaluation of a Web-Based Insulin Self-Titration System:

Preliminary Results 1209

Wouter T. Gude, Airin C.R. Simon, Linda W.P. Peute, Frits Holleman, Joost B.L. Hoekstra, Niels Peek and Monique W.M. Jaspers

MInD: Moving in the Dark 1212

A. Pepino, G. Sicignano, M. Rovani and G. D’Addio An Example of a Multi-Professional Process-Oriented Structured

Documentation Bound to SNOMED CT 1215

Carina Zetterberg, Karin Ahlzén, Erika Ericsson and Bengt Kron Clinicians’ Experiences with Videoconferencing in Psychiatry 1218

Rolf Wynn, Svein Bergvik, Gunn Pettersen and Sturla Fossum

xxix

Development and Management of Public Health Education System Against

Emerging Infectious Diseases 1221

Myungja Koh, Parvati Dev, Eun-Jung Lee, Byung-Ki Koo, Kyung-Oak Lee, Kukhwa Ha, Heesun Yang, Gilwon Kang and Youngsung Lee

Pharmaceutical Validation of Medication Orders Using an OWL Ontology and

Business Rules 1224

Amina Chniti, Abdelali Boussadi, Patrice Degoulet, Patrick Albert and Jean Charlet

A Way to Motivate Danish GPs to Implement a New National Service 1227

Alice Kristensen and Bente Wengler Trend Analysis and Future Development of Taiwan Electronic Medical Records 1230

Wan-Chi Ke, Yi-Chung Hsieh, Yen-Chen Chen, En-Te Lin and Hung-Wen Chiu

Subject Index 1233

Author Index 1243

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