QV Flare Up RangeThe symptoms of eczema can be very • distracting and disturbing for the sufferer.

The QV Flare Up Range of Wash, Cream • and Bath Oil provides for all over, all day therapy for flare ups.

Bath Oil• - Ideal for treating large areas of skin and for treating young children.

Wash• - Ideal for treating smaller areas of skin and when a full bath is not possible or practical.

Cream• - For ongoing care of the skin throughout the day.

Break the itch-scratch cycle

QV Flare Up Bath Oil2% Benzalkonium chloride, 0.7% triclosan, 65.1% light liquid paraffin•

QV Flare Up Bath Oil’s dual action formulation reduces the level of bacteria on the skin and • leaves an emollient film to help restore the skin’s moisture, suppleness and softness.

In accordance with the story patch test results, the combination of benzalkonium • chloride and triclosan in QV Flare Up Bath Oil, reduces S. aureus levels.

Light liquid paraffin is used as an emollient. It leaves a thin film of emollient oil on the • skin which reduces the loss of water from the stratum corneum to the environment.1 It effectively hydrates the skin and enables softening of the outer layer of the stratum corneum through endogenous hydration.1 Liquid paraffin as an emollient promotes rehydration of the skin and skin suppleness.2

QV Flare Up WashGlycerin, cetrimonium bromide, benzalkonium chloride, disodium EDTA, lactic acid•

A gentle cleansing formulation to relieve atopic eczema.•

QV Flare Up Wash works to relieve atopic eczema by gently cleansing the skin and • removing bacteria that can aggravate eczema.

Bacterial levels on the skin, particularly • S. aureus, correlates with the incidence and severity of eczema. By reducing S. aureus levels, a resulting improvement in the condition can be seen.

QV Flare Up Wash works to relieve site specific atopic eczema and flare ups.•

An in vivo study showed that QV Flare Up Wash achieved a log reduction in bacteria of 3.5968 +/- 0.57 that was significantly larger than achieved by the reference soap which had a log reduction of 2.7162 +/- 0.33.

- Tested according to the EN 1499 - Chemical Disinfectants and Antiseptics - Hygenic Handwash.

Data held on file by Ego Pharmaceuticals.

QV Flare Up Cream0.1% Benzalkonium chloride, 10.0% liquid paraffin, 5.0% petroleum jelly, 10% glycerin, 1.0% • povidone, 0.3% parabens and 1.0% phenoxyethanol

QV Flare Up Cream is a highly emollient cream for the topical relief of eczema. The emollient • properties of QV Flare Up Cream improve the symptoms of eczema by providing an emollient action which restores skin hydration and relieves associated itching and irritation.

Contains 1.0% povidone, which is inert, non-sensitizing and non-irritating.• 3 Povidone can form molecular adducts with many other substances and can bind various toxins, viruses, dyes, potent drugs, and other chemicals.4 This complexing ability provides an anti-irritant action.5,6,7 The case of iodine is illustrative as the povidone iodine complex retains the full germicidal properties of elemental iodine while oral toxicity to mammals is drastically reduced.4 Providone also promotes emolliency and lubricity to help relieve inflammation and redness.4

10% glycerin in QV Flare Up Cream helps increase skin hydration, skin elasticity and aids in • barrier recovery, lipid synthesis and cell proliferation. Glycerin is a non volatile hydroscopic liquid and when applied topically draws transepidermal water to the surface of the skin resulting in hydration of the stratum corneum.8, 9 Glycerin has been shown to have a significant effect on skin mechanics and may have an additional function to that of a humectant alone by maintaining the liquid crystalline state of the lipids within the stratum corneum.10

Free from lanolin, propylene glycol and fragrance.•

www.qvskincare.com.au

EGO PHARMACEUTICALS PTY LTD, 21-31 Malcolm Road, Braeside, 3195, Australia phone +61 3 9587 1088 toll free 1800 033 706 dubai +971 4258 8433 singapore +65 6562 7755 malaysia +60 3 7956 8868 new zealand toll free 0800 368 452

‘Ego’ and ‘QV’ are trademarks of Ego Pharmaceuticals Pty Ltd in Australia and other countries. ©2010 Ego.

ask@egopharm.com www.egopharm.com

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References: 1. Blank IH. Emollients. In The Chemistry and Manufacture of Cosmetics 2nd edition. Florida; The Continental Press; 1975. p. 15-24. 2. Hunting ALL. Encyclopedia of Conditioning Rinse Ingredients. London; Micelle Press; 1987. p. 280-281. 3. Robinson BV, Sullivan FM, Borzelleca JF, Schwartz SL. PVP: A critical review of the kinetics and toxicology of polyvinylpyrrolidone (povidone). Michigan; Lewis Publisher; 1990. p. 149 4. PVP Polyvinylpyrrolidone: physical, chemical, physiological and functional properties. GAF Corporation Technical Bulletin 2550-006;12-13. 5. Blecher L, Lorenz DH, Lowd HL, Wood AS, Wyman DP. Polyvinylpyrrolidone. In Handbook of water soluble gums and resins. McGraw-Hill; 1980. p. 13-15. 6. Prescott F J, Hahnel E, Day D. Cosmetic PVP: Part 1, Drug Cos Ind 1963; 93(4):443-541. 7. Goldemberg R L. Use of anti-irritants in cosmetic formulating. J. Soc. Cosmetic Chemists 1965; 16:317-340 8. Wehr RF, Krochmal L. Considerations in Selecting a Moisturizer. Cutis 1987; 39:512-515. 9. Bissett DL, McBride JF. Skin Conditioning with Glycerol. J. Soc. Cosmetic Chemist 1984; 35:345-350. 10. Pedersen JK, Jemec GBE. Plasticising effect of water and glycerin on human skin in vivo. J. Derm Sci 1999; 19:48-52.