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Report of Centre for Biotechnology SIKSHA ‘OANUSANDHAN (A Deemed to be University declared u/s 3 of the UGC Act, 1956) Re-Accredited by NAAC with ‘A’ Grade Bhubaneswar, Odisha

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Page 1: Report of Centre for Biotechnology

Report of Centre for Biotechnology

SIKSHA ‘O’ ANUSANDHAN (A Deemed to be University declared u/s 3 of the UGC Act, 1956)

Re-Accredited by NAAC with ‘A’ Grade Bhubaneswar, Odisha

Page 2: Report of Centre for Biotechnology

Centre for Biotechnology (CBT)

Achievements in Last Five Years ( 2015-20) 1. A BRIEF INTRODUCTION:

The Centre for Biotechnology, located at Bhubaneswar was established under Siksha ‘O’

Anusandhan (Deemed to be University) in 2006 with the aim to impart qualitative education

and carryout research in Biotechnology. Now a day the Centre has evolved as a learning

ambience that is flexible and suitable for dissemination of knowledge in frontier areas of

Biotechnology. The Centre has the objective to promote professional education, research and

development and training in different areas of Biotechnology so as to cater to the need of the

country. The Centre is actively running several degree courses like M.Sc. in Biotechnology,

Integrated MSc in Biotechnology and Ph.D. in Biotechnology. The Centre is involved in

advance research in different fields like plant, animal, microbial and pharmaceutical

biotechnology. The Centre is funded with multiple research projects from different funding

agencies like DBT, DST, SERB, ICMR, Ministry of Mines etc. The Centre has published

more than 300 research articles in peer reviewed national and international journals.

2. OBJECTIVE OF THE CENTRE:

Objective: The Centre for Biotechnology, is a DST-FIST, New Delhi supported center,

operational under the aegis of Siksha O Anusandhan University, Bhubaneswar. It has been

thriving for excellence in academics and research in the arena of Life sciences since its

inception in the year of 2006. The center is growing lips and bounds with three basic

objectives; (i) To build a research-oriented college through specialization in Life Sciences

and Biotechnology, (ii) To employ a future-oriented curriculum in order to meet the need for

bioengineering specialists and (iii) To establish a sustainable research program through

interdisciplinary convergence.

Progress: We unfolded our first post graduate program, M. Sc. in Biotechnology soon after

one year of its inception in 2007 with the help of a handful of faculty members supported

with few basic laboratory facilities and launched few more new post graduate program, M.

Sc. in Molecular Biology and M.Sc. in Aromatic and medicinal plants in consequent years.

We started our research in major areas focusing on plant, microbiological and pharmaceutical

biotechnology. The institute kept growing with added on infrastructure, specialized

laboratory facilities, better trained dynamic faculty members and new technology programs;

graduation (B.Tech in Biotechnology) and post-graduation programs (M. Tech in

Biotechnology) in addition to five years integrated Biotechnology program. The externally

funded research projects from sponsoring agencies like DST, SERB, DBT, UGC, ICMR and

MOM, Government of India further added strength in conducting hi-tech research in

interdisciplinary subject area, development of analytical facilities, and help us in floating

Ph.D and post-doctoral programs. At this point of time, we have nine well-furnished

laboratory with state-of-the art facilities which are available to the students, research scholars

and faculty members of the Centre. The faculty and research scholar together added strength

to the R and D in many different areas of life science research with incredible number of

publications (300) in peer reviewed journals of national and international repute as well as

Page 3: Report of Centre for Biotechnology

book chapters and books published by Springer and Elsevier publishing houses. To our

credit, we have filed seven Indian patents. As social responsibility, the work is going on in

collaboration with CRTD (Centre for Rural and Tribal development) for livelihood

generation of community through production of value added products by Biotechnological

intervention using aromatic and medicinal plants (Turmeric, Ginger, Kampferia, Moringa,

Tulsi etc.). We have developed disease diagnostic kits to detect human diseases (Malaria) and

plant disease (Turmeric rot). To make our research available, the students of other

universities are allowed to undergo training in advance fields of Biotechnology for their

dissertation. The unbound growth of the Centre could attract national and international

research collaborations with reputed laboratories (University of Madison, USA and Institute

of Biological & Biomedical Sciences, United Kingdom).

3. JOURNEY IN BRIEF:

THRUST AREAS

1. PLANT BIOTECHNOLOGY:

• Assessment of drug yielding traits of important medicinal plants from different

geographical regions of India.

• Bioprospecting of some underexplored medicinal plants of Zingiberaceae.

• Development of chemical fingerprint of important medicinal plants for authentic

identification and quality control of drug.

• Development of Artificial Neural Network (ANN) based prediction model for

drug yield optimization in important medicinal plants.

• Improvement of essential oil yield of high valued aromatic plants through

biotechnological approach.

• In vitro conservation of rare, endangered and threatened medicinal plants.

2. MOLECULAR BIOTECHNOLOGY:

• Molecular cloning, characterization and expression analysis of biotic stress

resistance in spice crops.

• Transcriptomic approaches for identification, cloning and characterization of high

value aroma molecules from the unexplored plants.

• Development of resistant variety of Capsicum annum L. against Chilli leaf curl

virus (ChLCV).

3. MICROBIAL BIOTECHNOLOGY:

• Functional genomic based elucidation of molecular mechanism(s) behind Colistin

resistance and in silico repurposing of FDA approved drugs as adjuvants targeting

colistin restoration.

• Functional metagenomics based evaluation of the role of anthropogenic activity

on prevalence and transmission of resistant bacteria and genes in river system.

Page 4: Report of Centre for Biotechnology

• Large scale production of microbial biosurfactant from low cost raw materials and

its application on various biotechnological fields.

4. ANIMAL BIOTECHNOLOGY:

• Screening of novel antimicrobial and immune-modulatory molecules from Indian

medicinal plants and their use in adjunct therapy or immunotherapy of

tuberculosis.

• Investigating the anti- amyloidogenic propensity of nanoparticles – A promising

strategy to develop novel anti- Alzheimer's drugs.

• Understanding the putative role of anthropogenic environmental toxicants in

inducing neurodegenerative diseases and identification of possible therapeutic

intervention.

5. ENVIRONMENTAL BIOTECHNOLOGY:

• Decolorization and detoxification of industrial waste water and its reuse for

sustainable development.

• Environmental quality assessment, bioremediation and biochemical basis of

environmental stress monitoring.

4. PERSONNEL INVOLVED: (At present)

Faculty : 16

Research Scholar : 32

PG Students : 220

5. COLLABORATION OF THE CENTRE:

The collaborative institutes of CBT are listed below

a) Institute of Life Science, Bhubaneswar

b) Sambalpur University, Sambalpur

c) Rama Krishna Mission Centenary College, West Bengal

d) Ramadevi Women’s University, Bhubaneswar

e) Fragrance and Flavour Development Centre, Uttar Pradesh

f) Fragrance and Flavour Development Centre Extension Unit, Berhampur, Odisha

g) Institute of Chemical Technology, ICT Mumbai-IOC Odisha Campus, Bhubaneswar

h) ICFRE- Himalayan Forest Research Institute, Shimla

i) ICMR-Regional Medical Research Centre, Bhubaneswar

j) University of Madison, USA

k) Institute of Biological & Biomedical Sciences, United Kingdom

6. PROJECTS: No of Sanctioned Projects: 47; Ongoing: 22; Completed: 25

7. PUBLICATION: Research & Review article: 226; Book & Book chapter: 21

Page 5: Report of Centre for Biotechnology

PATENTS: 7 (Filed)

Process & Products:

• Development of high oil yielding turmeric genotype through tissue culture.

• Development of ICT kit for early detection of rhizome rot in turmeric.

• Development of kit for rapid diagnosis of malaria from human urine.

• Development of SCAR marker for early detection of rhizome rots disease in turmeric.

• Development of molecular marker for identification of turmeric cultivars (Lakadong and

Suvarna).

GENE SEQUENCE SUBMISSION: 103

8. STUDENTS GRADUATED

Ph.D. : 29

P.G. : 245

9. EQUIPMENT AVAILABLE

Generic Name of Equipment Model, Make & year of purchase

Horizontal & vertical

Electrophoresis

Tarson–7050&7090, 2006 Genei Sub

marine (medium & big, 2007)

HPTLC Camag, 2014

HPLC Shimadzu, 2017

Gel Documentation System BioRad, 2007, 2015

Thermocycler (PCR) Applied Biosystem, 2010

Real Time Thermocycler (PCR) Applied Biosystem (Step One Plus),

2015

GC-MS Perkin Elmer, Clarus 580 with Clarus

SQ 8S MS, 2014

Tissue Culture Room with

Photoperiod Controlled Rack

Vista Biocell-V-0230M, 2005

Deep freezer (-20 º C) Vest Frost – 250lt, 2006

UV Transilluminator Genei/T-20, 2005

Deep freezer (-80 º C) Remi, 2012

Electronic Analytical Balance Denver – APX-200, 2005

Electronic Balance Shimadzu –ELS- 300, 2005

Laminar Air Flow Klenzoids, 2005

Trinocular Microscope B.D-Loboscope-BD-156/2005

pH Meter Systronics-335, 2005

Hot Air Oven B.D. Instruments BD-50, 2006

Magnetic Stirrer B.D. Instruments B.D-42, 2005

High Speed Centrifuge Remi/C-24BL, 2005

Autoclave B. D. Instruments BD-57, 2005

Refrigerator LG-Intello, 2006

Clevenger’s apparatus Borosil, 2008

Soxhlet’s apparatus Borosil, 2008

Water Bath Osworld – JRIC-39, 2006

Digital Camera Nikkon-Coolpix4600, 2006

B.O.D Incubator

Page 6: Report of Centre for Biotechnology

Orbital shaker

IR (Infra-Red Spectroscopy)

Pletismograph

Incubator

Page 7: Report of Centre for Biotechnology

10. ACHIEVEMENTS, AWARDS ACCOLADES:

Sl no Name of faculties/

research scholar

receiving awards

from state level,

national level,

international level

Year of

Award

Designation Name of the award, fellowship,

received from Government or

Government recognised bodies

Name of the Awarding

Agency

Incentives/Type of

the incentive given

by the HEI in

recognition of the

award

1 Dr Ananya Kuanar 2016 Assistant

Professor

NPDF,DST DST NIL

2 Dr Ananya Kuanar 2017 Assistant

Professor

International Travel Award to

Ageri Egypt

ICGEB, New Delhi NIL

3 Geetanjali Rajhans 2019 Research

scholar

Best Poster Award Central University of

Haryana

NIL

4 Dr. Sanghamitra Nayak 2017 Professor &

Head

13th Dr. P.D. Sethi Annual

Award – 2017 for Best Paper,

Kongposh Publications Pvt.Ltd.,

New Delhi

Kongposh Publications

Pvt. Ltd., New Delhi

NIL

5 Dr. Sanghamitra Nayak 2018 Professor &

Head

14th Dr. P.D. Sethi Annual Award

– 2018, Kongposh Publications

Pvt. Ltd., New Delhi

Kongposh Publications

Pvt. Ltd., New Delhi

Rs 10000.00

6 Ambika Sahoo 2018 Research

scholar

Certificate of Merit EOAI International

Congress & EXPO 2018

“Navigating Future of

Essential Oils” held at

Whitefield, Bengaluru,

India

NA

Page 8: Report of Centre for Biotechnology

7 Sudipta Jena 2018 Research

scholar

Best Poster award 2nd International

Conference on

Biotechnology and

Biological Sciences held

at University of

Engineering and

Management, Kolkata

NA

8 Noohi Nasim 2018 Research

scholar

2nd Position in Poster

Presentation

EOAI International

Congress & EXPO 2018

“Navigating Future of

Essential Oils” held at

Whitefield, Bengaluru,

India

NA

9 Asit Ray 2018 Research

scholar

Certificate of merit EOAI International

Congress & EXPO 2018

“Navigating Future of

Essential Oils” held at

Whitefield, Bengaluru,

India

NA

10 Asit Ray 2018 Research

scholar

Young Scientist 49th International

Symposium on Essential

oils (ISEO 2018)

NA

Page 9: Report of Centre for Biotechnology

11 Asit Ray 2018 Research

scholar

Young Scientist An international

Conference on Innovation

and Translational

Dimensions: Food, Health

and Environmental

Biotechnology held at

MNNIT, Allahabad

NA

12 Bhuban Mohan

Padhiari

2020 Research

scholar

Prof. B. K. Nanda memorial

Award

Orissa Botanical Society NA

13 Bibhuti Bhusan

Champati

2020 Research

scholar

2nd Position in Poster

presentation (Ethnobotany-

Biotechnology interface)

Department of Botany and

Biotechnology,

Ravenshaw University,

Cuttack.-753003

NA

14 Dr. Enketeswara

Subudhi

2017 Professor Oral Presenation-First Place S'O'A+Springer NA

15 Suchanda Dey 2019 Research

scholar

Best Poster IIT, Rurkee NA

16 Dr. Basudeba Kar 2017 Assistant

Professor

Best Oral Presentation Award Endling scientific

organization, Philippines

NA

17 Dr. Basudeba Kar 2015 Assistant

Professor

Sarojini G. Panigrahi Young

Scientist Award

Odisha Botanical Society NA

18 Dr. Basudeba Kar 2018 Assistant

Professor

Best Poster Presentation Award EOAI international

congress & expo 2018

"Navigating future of

essential oils"

NA

19 Dr. Debapriya

Bhattacharya

2020 Assistant

Professor

Bill and Melinda Travel Heath

Grant Award for tuberculosis

symposium held on New Mexico,

USA

Bill and Melinda

foundation and Key stone

symposium body

Fully funded

including travel,

registration and

boarding

Page 10: Report of Centre for Biotechnology

11. EVENTS ORGANIZED:

I. 2020

1) PUGLB-II, 2020

Workshop on “Programme for Under graduate leadership in biotechnology –II, 2020”

Theme of the Event: Workshop on Principles and Applications for Analytical Instruments for Bioanalysis

Organized by – Centre For Biotechnology

Date – 8th February 2020

Summary of Activities- 44 participants registered and participated. The workshop was organized on 8th

February 2020at Centre for Biotechnology, School of Pharmaceutical Sciences, Campus-2, Siksha ‘O’

Anusandhan (Deemed to be University), Bhubaneswar. The workshop focused on both the theoretical and

practical knowledge of analytical instruments such as HPLC,GCMS, HPTLC, PCR etc. The session was

followed by quiz and valedictory function.

Significant Outcomes – Participants were able to understand the importance and utility of bio-analytical

tools.

2) PYGLB-X

Workshop on “Programme for Young graduate leadership in biotechnology -X”

• Theme of the Event – Hands- on-training on Bio-analytical tools

• Organized by – Centre For Biotechnology

• Date (From – To) –28th -29th February 2020

Summary of Activities - 50 participants registered and participated. The inaugural session was held on

28.02.2020 at Centre for Biotechnology, School of Pharmaceutical Sciences, Campus-2, Siksha ‘O’

Anusandhan (Deemed to be University), Bhubaneswar, followed by demonstration and hands-on-training

on the analytical equipments and techniques. On 29.02.2020, the hands-on-training was continued in the

first session, followed by quiz and valedictory function.

Significant Outcomes – Participants were able to learn and acquire a brief idea of handling analytical

tools.

II. 2019

1) PUGLB-I, 2019

Workshop on “Programme for Under graduate leadership in biotechnology -2019”

• Theme of the Event – Workshop on Bio-analytical Techniques

• Organized by – Centre For Biotechnology

• Date – 29th January 2019

Summary of Activities- 40 participants registered and participated. The workshop was organized on

29.01.2019 at Centre for Biotechnology, School of Pharmaceutical Sciences, Campus-2, Siksha ‘O’

Anusandhan (Deemed to be University), Bhubaneswar. The workshop focused on both the theoretical and

Page 11: Report of Centre for Biotechnology

practical knowledge of analytical instruments such as HPLC, GCMS, HPTLC, PCR etc. The session was

followed by quiz and valedictory function.

Significant Outcomes – Participants were able to understand the importance and utility of bio-analytical

tools.

2) PYGLB-IX, 2019

Workshop on “Programme for Young graduate leadership in biotechnology –IX, 2019”

• Theme of the Event – Hands- on-training on Bio-analytical tools

• Organized by – Centre For Biotechnology

• Date (From – To) – 22nd – 23rd February 2019

Summary of Activities - 50 participants registered and participated. The inaugural session was held on

22.02.2019 at Centre for Biotechnology, School of Pharmaceutical Sciences, Campus-2, Siksha ‘O’

Anusandhan (Deemed to be University), Bhubaneswar, followed by demonstration and hands-on-training

on the analytical equipments and techniques. On 23.02.2019, the hands-on-training was continued in the

first session, followed by quiz and valedictory function.

Significant Outcomes – Participants were able to learn and acquire a brief idea of handling analytical

tools.

III. 2018

1) PYGLB-VIII, 2018

Workshop on “Programme for Young graduate leadership in biotechnology –VIII, 2018”

• Theme of the Event – Hands- on-training on Bio-analytical tools

• Organized by – Centre For Biotechnology

• Date (From – To) – 23rd to 24th February 2018

Summary of Activities - 53 participants registered and participated. The inaugural session was held on

23.02.2018 at Centre for Biotechnology, School of Pharmaceutical Sciences, Campus-2, Siksha ‘O’

Anusandhan (Deemed to be University), Bhubaneswar, followed by demonstration and hands-on-training

on the analytical equipments and techniques. On 24.02.2018, the hands-on-training was continued in the

first session, followed by quiz and valedictory function.

Significant Outcomes – Participants were able to learn and acquire a brief idea of handling analytical

tools.

IV. 2017

1) PYGLB-VII, 2017

Workshop on “Programme for Young graduate leadership in biotechnology –VII, 2017”

• Theme of the Event – Hands- on-training on Bio-analytical tools

• Organized by – Centre For Biotechnology

• Department – Centre For Biotechnology

Date (From – To) –17.02.2017 to 18.02.2017

Page 12: Report of Centre for Biotechnology

Summary of Activities - 52 participants registered and participated. The inaugural session was held on

17.02.2017 at Centre for Biotechnology, School of Pharmaceutical Sciences, Campus-2, Siksha ‘O’

Anusandhan (Deemed to be University), Bhubaneswar, followed by demonstration and hands-on-training

on the analytical equipments and techniques. On 18.02.2017, the hands-on-training was continued in the

first session, followed by quiz and valedictory function.

Significant Outcomes – Participants were able to learn and acquire a brief idea of handling analytical

tools.

V. 2016

1) PYGLB-VI, 2016

Workshop on “Programme for Young graduate leadership in biotechnology –VI, 2016”

• Theme of the Event – Hands- on-training on Bio-analytical tools

• Organized by – Centre For Biotechnology

• Department – Centre For Biotechnology

Date (From – To) – 17.02.2016 to 18.02.2016

Summary of Activities – 50 participants registered and participated. The inaugural session was held on

17.02.2016 at Centre for Biotechnology, School of Pharmaceutical Sciences, Campus-2, Siksha ‘O’

Anusandhan (Deemed to be University), Bhubaneswar, followed by demonstration and hands-on-training

on the analytical equipments and techniques. On 18.02.2016 the hands-on-training was continued in the

first session, followed by quiz and valedictory function

Significant Outcomes – Participants were able to learn and acquire a brief idea of handling analytical

tools.