the international centre for genetic engineering and biotechnology
DESCRIPTION
The International Centre for Genetic Engineering and Biotechnology. This course is sponsored by. Welcome. Advanced Bioinformatics:. Computational Systems Biology. Fernando Alvarez, Alberto Ferrarini, Massimiliano Gentile, Attila Kert ész Farkas , Mike Myers, S ándor Pongor. - PowerPoint PPT PresentationTRANSCRIPT
The International Centre for Genetic Engineering and Biotechnology
The International Centre for Genetic Engineering and Biotechnology
Welcome
This course is sponsored byThis course is sponsored by
Computational Systems Biology Computational Systems Biology
Trieste, 3-7 October, 2011
Fernando Alvarez, Alberto Ferrarini, Massimiliano Gentile, Attila Kertész Farkas, Mike Myers, Sándor Pongor
Advanced Bioinformatics:Advanced Bioinformatics:
Secretariat:Elisabetta Lippolis
Chiara Alberti
Computer system manager:Dario PalmisanoDiego Soldano
Course assistant: Mircea Pacurar
Accounts:Giulia Bon, Lisa Sessi
Barbara Leggieri
ICGEB programsICGEB programs
Research Research
Training: Ph.D., Training: Ph.D., postdoctoral and postdoctoral and specialized coursesspecialized courses
Research grantsResearch grants
Services: Bioinformatics, Services: Bioinformatics, Biotech process Biotech process development, Biosafety development, Biosafety consultingconsulting
ICGEB coursesICGEB courses
12-15 courses yearly12-15 courses yearly
Theoretical courses (50 students) Theoretical courses (50 students) and practical courses (up to 30 and practical courses (up to 30 students)students)
Mainly molecular biologyMainly molecular biology
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1988 1989 1990 1996 1998 2002 2003 2004 2005 2006 2007
Participants
Protein Structure and BioinformaticsProtein Structure and Bioinformatics
Established as a resource Established as a resource group for protein chemistry group for protein chemistry and protein engineeringand protein engineering
In charge of bioinformatics In charge of bioinformatics services since 1991services since 1991
Research projects on Research projects on bioinformatics, structural bioinformatics, structural biology, systems modelling, biology, systems modelling, bacterial communicationbacterial communication
Currently includes 12 Currently includes 12 researchers and studentsresearchers and students
ICGEB bioinformaticsICGEB bioinformatics
Biological computing service Biological computing service for 800 users from 35 for 800 users from 35 countriescountries
2-3 training courses per year, 2-3 training courses per year, 1500+ students in 20 years...1500+ students in 20 years...
Methods development Methods development (classification, machine (classification, machine learning)learning)
WWW-services: DNA-tools, WWW-services: DNA-tools, protein domain identificationprotein domain identification
Computational Systems Biology Computational Systems Biology
Trieste, 3-7 October, 2011
Fernando Alvarez, Alberto Ferrarini, Massimiliano Gentile, Attila Kertész Farkas, Mike Myers, Sándor Pongor
Advanced Bioinformatics:Advanced Bioinformatics:
Secretariat:Elisabetta Lippolis
Chiara Alberti
Computer system manager:Dario PalmisanoDiego Soldano
Course assistant: Mircea Pacurar
Accounts:Giulia Bon, Lisa Sessi
Barbara Leggieri
Molecular biologyMolecular biology Systems biology
Traditional wet lab methods
Traditional wet lab methods
High throughput technologies
Approaches based on data collection
Bioinformatics IBioinformatics I
Computer support for traditional molecular biology (cloning, Computer support for traditional molecular biology (cloning, sequencing). sequencing).
Concentrates on singe genes and proteins. Well-defined Concentrates on singe genes and proteins. Well-defined problems, small, validated datasets.problems, small, validated datasets.
Compares single genes, gene groupsCompares single genes, gene groups
““Simple databases”Simple databases”
Annual bioinformatics course „Computer methods in molecular biology”
Bioinformatics IIBioinformatics II
Computer support for high throughput technologies (genomics, Computer support for high throughput technologies (genomics, proteomics). proteomics).
Concentrates on system-wide responses. Vaguely defined Concentrates on system-wide responses. Vaguely defined problems, large raw datasets.problems, large raw datasets.
Compares complex data (genomes, gene expression profiles Compares complex data (genomes, gene expression profiles etc).etc).
Uses Uses both both traditional and complex, integrated databases.traditional and complex, integrated databases.
...This course
The problemsThe problems
Many Many differentdifferent data-collection methods data-collection methods
Method-specific approaches (programs, data-formats etc.)Method-specific approaches (programs, data-formats etc.)
Short life-span of individual methods. Short life-span of individual methods.
No unified teaching perspectiveNo unified teaching perspective
This courseThis course
Next Generation Sequencing Next Generation Sequencing (Mon-Tue) (Mon-Tue)
Fernando Alvarez (Montevideo)Fernando Alvarez (Montevideo)
Alberto Ferrarini (Verona) Alberto Ferrarini (Verona)
Massimiliano Gentile (Helsinki)Massimiliano Gentile (Helsinki)
ProteomicsProteomics (Wed-Thu) (Wed-Thu)
Michael P. MyersMichael P. Myers (ICGEB) (ICGEB)
Attila KertAttila Kertéészsz--FarkasFarkas (ICGEB) (ICGEB)
Genome annotationGenome annotation (Fri) (Fri)
Laurent Falquet (Lausanne)Laurent Falquet (Lausanne)
The International Centre for Genetic Engineering and Biotechnology
The International Centre for Genetic Engineering and Biotechnology
Welcome
This course is sponsored byThis course is sponsored by