research and innovation mr ken lavery, medical director

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RESEARCH AND INNOVATION Mr Ken Lavery, Medical Director

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RESEARCH AND INNOVATIONMr Ken Lavery, Medical Director

PHILOSOPHY

•Holistic approach•Translational•Clinically led•Multidisciplinary•Developing•Expansion

ANNUAL GENERAL MEETING, 29 JULY 2010

PARTNERS I

• QVH

• Blond McIndoe Research Foundation

• Brighton and Sussex Medical School

• University of Brighton

ANNUAL GENERAL MEETING, 29 JULY 2010

PARTNERS II

ANNUAL GENERAL MEETING, 29 JULY 2010

INFRASTRUCTURE I

ANNUAL GENERAL MEETING, 29 JULY 2010

ClinicalClinical Management Management

TranslationalTranslationalResearchResearch

HealthcareHealthcareOutcomesOutcomes

EducationEducationDevelopmentDevelopment

INFRASTRUCTURE II

• Translational research: from the lab to the patient

• Healthcare outcomes: supported by Clinical Audit, P.R.O.M.S. (patient reported outcome measures)

• Educational “give me the boy and I will give you the man” involving the medical students in our work and inspiring them to take it forward to the next step in their turn

ANNUAL GENERAL MEETING, 29 JULY 2010

QVH MODEL

ANNUAL GENERAL MEETING, 29 JULY 2010

• Clinician ledClinician led• Self fundingSelf funding• University/Charity/HospitalUniversity/Charity/Hospital• Clinicians of the futureClinicians of the future• Flexible/ProactiveFlexible/Proactive• Collaborative researchCollaborative research

Clinical Clinical ManagementManagement

TranslationalTranslationalResearchResearch

HealthcareHealthcareOutcomesOutcomes

EducationEducationDevelopmentDevelopment

TRANSLATIONAL RESEARCH

• Wound biology – pH, in vitro• Anti-scarring• Pain control• Skin graft management• Biomaterials – nanofibres, microcarriers carbon• Psychology - back to work• Sepsis - finger print, immunology

ANNUAL GENERAL MEETING, 29 JULY 2010

RESEARCH / EDUCATION

• Clinician involvement• Taught courses• Progression

ANNUAL GENERAL MEETING, 29 JULY 2010

StudentsIRPBSc

Post GraduateMD fellow

MRes

Burns FellowClinical Research

Pre consultant

QVH MODEL

• Healthcare outcomes• Clinical management - surgical, sepsis, commercial, pharmocokinetics • Education and Development

ANNUAL GENERAL MEETING, 29 JULY 2010

STRENGTHS

• Clinical + Science• Personnel• Wide research

programme• Education• Collaborations

• Patient driven• Cycle of research• Multi-faceted/

disciplinary• Facilities• Managerial/SHA buy in

ANNUAL GENERAL MEETING, 29 JULY 2010

CURRENT STATUS• Joint grant applications with BMRF Prof. Lawrence-Watts as

research consultant for QVH and BMRF• Collaborations• Medical student IRP’s• Research Nurse• NIHR links• Military links• Joint appointments• Research links mirror clinical links• Wider research portfolio for each member

ANNUAL GENERAL MEETING, 29 JULY 2010

BENEFITS• Local model with logical development• Enhance vs create• Pump priming - plan to establish Chair• Patient driven• Self sustaining• Develops future clinicians• Efficient use of resources

ANNUAL GENERAL MEETING, 29 JULY 2010

CURRENT ACTIVITY

• 24 Research projects currently funded and on-going including nationally clinically important work in:– Pain Relief; Paracetomol Study; major study on post-operative pain

relief Anaesthetics and Maxillofacial Departments– Patient psychological outcomes after breast surgery reconstruction in

both men and women, in collaboration with the University of West of England

– Long term outcomes for paediatric burn injury; a major study with already 120 patients recruited

– Wound healing and scar management– Limbal Cell Sheets for ocular surface rehabilitation Corneo-plastic

department

ANNUAL GENERAL MEETING, 29 JULY 2010

INNOVATION

• Development of medical devices the QVH has active liaison with NHS Innovations to develop the commercial aspects and ensure the Trust retains the intellectual property and a prototype of a medical device is now ready for clinical trial

• Three other innovations are being actively pursued

ANNUAL GENERAL MEETING, 29 JULY 2010

FUNDING

• The $64,000 question • The Money!• Charitable funds• The Trust is re-organising its charitable funds to

make more money available for Research and Development, recognising that research grants may become more challenging to obtain

• More flexibility should allow more and larger projects to be self-funded

ANNUAL GENERAL MEETING, 29 JULY 2010

SUMMARY

• Research and Development has always been at the core of clinical activity at QVH

• We “punch well above our weight” in terms of the amount and quality of research that we are produce

• Major academic units see us as a very important partner in their research endeavours

• Research keeps our profile high nationally and internationally

• Its not a “nice to do” its for us a “must do”

ANNUAL GENERAL MEETING, 29 JULY 2010