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1 RESEED® PRESENTATION INDEPENDENT CLINICAL TRIAL THE ULTIMATE SOLUTION FOR MEN AND WOMEN WITH HAIR LOSS

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Page 1: RESEED® PRESENTATION - AEPC UK Ltd. Clinical Trial Presentation.pdf · R12 TRI PEPTIDE ACTIVE HAIR SERUM: 30ml ... SPQ (Self-Assessment Questioner) Results Over 8 Week Period -Subjects

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RESEED® PRESENTATION

INDEPENDENT CLINICAL TRIAL

THE ULTIMATE SOLUTION FOR MEN AND WOMEN WITH HAIR LOSS

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Contents

1. The Reseed® Products

- For Men

- For Women

2. Introduction To The Reseed® System

3. How To Use The Reseed® System

4. Independent Clinical Trial

- Summary

- Observation

- Conclusion

- Statistical Graphs

- Subjects Completing Questionnaire

- Clinical Test & Approval

- Photos

5. Ingredients List

6. Hair Supplement

- R21 Micro-Nutrients

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1. The Reseed® Products

- For Men R12 TRI PEPTIDE ACTIVE HAIR SERUM: 30ml

SABAL & NEEM FORTIFYING SHAMPOO WITH ESSENTIAL PRO VITAMINS: 250ml

WHEAT BRAN ULTRA VOLUME CONDITIONER WITH HYDROLISED SILK: 250ml

R8 BOTANICAL SOLUTION WITH ROSEMARY & NETTLE: 50ml

R21 MICRO-NUTRIENTS FOOD SUPPLEMENT (Unisex): 30 days supply

- For Women

R12 TRI PEPTIDE ACTIVE HAIR SERUM: 30ml

GINGKO & SABAL FORTIFYING SHAMPOO WITH ESSENTIAL PRO VITAMINS: 250ml

WHEAT BRAN ULTA VOLUME CONDITIONER WITH POMEGRANATE COLOUR PROTECT: 250ml

R8 BOTANICAL SOLUTION WITH NETTLE & HORSETAIL: 50ml

R21 MICRO-NUTRIENTS FOOD SUPPLEMENT (Unisex): 30 days supply

2. Introduction To The Reseed System

We have between 100,000 and 150,000 hairs on our head. The number of strands of hair that is lost can vary,

but on average, we lose between 80-100 strands of hair per day. To maintain normal volume, hair must be

replaced at the same rate at which it is lost.

Changes to the growth cycle can occur due to a number of reasons such as hormonal imbalance, nutritional

deficiency or ageing. Where there is permanent baldness for example, due to hereditary predisposition, the hair

life cannot be prolonged. However, where there is life left in the follicle, the Reseed® system can help by

stimulating the life left in the follicle.

At Reseed we understand the importance of fuller looking, strong and healthy hair; how it affects self -

confidence, pride in appearance and sense of wellbeing. This is why our dedicated team of 35 highly

experienced specialists in the hair care field has created and produced Reseed, using the latest green bio -

technology to create a unique and highly innovative system for men and women – a new ground breaking

benchmark in proven high performance formulas that help to reverse the process of thinning hair.

Such is our commitment to hair excellence; the Reseed® system has taken 15 years to develop. Applying the

latest innovations and technologies, we have continually invested in resources to deliver the most effective

product range you can trust to deliver short and long term results.

Reseed® is dedicated to using the highest grade, naturally active ingredients and we never compromise on

quality as we exclusively farm and cultivate our own herbs and plants globally, so the quality is consistently

controlled in all our products. These powerfully efficacious, natural sources are selected and included for their

fortifying, stimulating and conditioning properties – bringing the results you want whilst caring for your hair and

scalp.

Our experts have accumulated vast amounts of data to create the unique Reseed® system that focuses entirely

on a holistic solution to hair loss - combining the best quality ingredients with functional packaging, to ensure

that all elements of hair loss are addressed efficiently.

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- The Scalp: FORTIFYING SHAMPOO & R8 BOTANICAL SOLUTION

- The Follicles: R12 TRI PEPTIDE ACTIVE HAIR SERUM

- The Diet: R21 MICRO-NUTRIENTS FOOD SUPPLEMENT

- The Hair: FORTIFYING SHAMPOO and ULTRA VOLUME CONDITIONER

The Reseed® System lays out a simple How to Use instruction in order to achieve optimum hair strengthening

and prolong the hair’s life cycle.

3. How To Use The Reseed System

To achieve optimum hair strengthening and prolong the hair’s life cycle, use all of the products in the Reseed®

system.

2 Phase usage SERUM* SOLUTION* SUPPLEMENT SHAMPOO CONDITIONER

Phase 1

usage:

Weeks 1+2

Apply serum

4 x a week N/A

Take

1 supplement

twice a day

Use as

frequently as

you would your

usual shampoo

Use as

frequently as

you would your

usual shampoo

Phase 2

usage:

Weeks 3-12

Apply serum

1 x a week

Apply solution

2 x a week

Take

1 supplement

twice a day

Use as

frequently as

you would your

usual shampoo

Use as

frequently as

you would your

usual shampoo

After the 12 weeks, continue to repeat Phase 2 on an ongoing basis.

*Do not use the SERUM and SOLUTION at the same time – instead alternate usage during the week.

4. Independent Clinical Trial

- Summary

A salon study in 25 healthy male and female subjects to measure the efficacy of a hair enhancing serum versus

a placebo product following a half head design.

Study design: Single-blind, half-head salon study.

Left Side: Placebo

Right Side: Reseed® Serum

Dose regime: 8 weeks daily use, half-head salon study.

Duration of treatment: 8 Weeks.

Number of subjects: Approximately 25

Type of subjects: Healthy volunteers of either sex, aged between 18 and 70 yrs.

Observations: Subjects attended the study salon on Study Days -3, 0, 14, 28, 42 and 56.

Page 5: RESEED® PRESENTATION - AEPC UK Ltd. Clinical Trial Presentation.pdf · R12 TRI PEPTIDE ACTIVE HAIR SERUM: 30ml ... SPQ (Self-Assessment Questioner) Results Over 8 Week Period -Subjects

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Subjects used a shampoo product provided by The Sponsor for 3 days prior to the study start. On Day 0, 14, 28

and 42 they underwent stylist assessments. On Day 56 they underwent final stylist assessme nts, they then

completed a Self-Perception Questionnaire (SPQ) and returned any unused product. Statistical analysis was

completed on Week 8 (Day 56).

Duration of study: Study Starts: w/c 30th September 2013

Study Ends: w/e 29th November 2013

Location: Aspen Clinical Research: United Kingdom

- Observations

For stylist assessments the test product performed statistically significantly better than the placebo product

(p<0.05) for all assessment criteria.

16% increase in growth and volume

20% improvement in general condition

For user self-evaluations the test product performed statistically significantly better than the placebo product

(p<0.05) for attributes of shine, volume, body and general condition.

For questionnaire results users showed a majority preference for the product in all questions and overall

preference.

- Conclusion

- 16% Significant change in the rate of hair growth

- 15% Noticeable improvement in the levels of shine, body and volume to the hair

- Over 91% of users said they would buy the product

For questionnaire results any result of top scores (4+5) showing over 80% of subject agreement validate related

claims.

It can be concluded that claims such as “improved body,” ‘Improved shine’, ‘Increased volume’ and ‘Improved

condition’ are all substantiated.

Improved body

Increase in shine Up to 20% improvement

Increase in volume

Improvement in general condition

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- Statistical Graphs

Stylist Assessment

(Chart 1)

Grading Scale

(Chart 1a is the grading scale for Chart 1)

GREASINESS SHINE VOLUME

0 Very greasy 0 No shine 0 Very limp, flyaway hair

1 Particularly greasy 1 Minimal shine 1 Limp flyaway hair

2 Greater than average grease 2 Reasonable shine 2 Average volume

3 Average levels of grease 3 Average shine 3 Greater than average volume

4 Little grease 4 Greater than average shine 4 Ample volume

5 Minimal to no grease 5 Just washed shine 5 Thick voluminous

Growth BODY GENERAL CONDITION/FEEL OF HAIR

0 No Growth 0 No body 0 Very poor feel/condition

1 Little Growth 1 Minimal body 1 Poor feel/condition

2 Average expected growth 2 Reasonable body 2 Reasonable feel/condition

3 Greater than expected 3 Average body 3 Average feel/condition

4 Large amount of growth 4 Greater than average body 4 Good feel/condition

5 Extreme growth 5 Full bodied 5 Great feel/condition

Page 7: RESEED® PRESENTATION - AEPC UK Ltd. Clinical Trial Presentation.pdf · R12 TRI PEPTIDE ACTIVE HAIR SERUM: 30ml ... SPQ (Self-Assessment Questioner) Results Over 8 Week Period -Subjects

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SPQ (Self-Assessment Questioner) Results Over 8 Week Period - Subjects Completing Questionnaire

Question 1:

Which product do you prefer?

Question 2:

Would you buy this product?

YES 20 (91%)

NO 2 (9%)

Placibo Serum No Preference

0

5

10

15

20

25

Which Product do you prefer?

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Question 3:

Q3a- What did you like most about the product? · “Made my hair grow a bit faster”

· “Think it made my hair grow a bit faster than normal”

· “I would probably buy it from a shop”

· “Nice smell”

· “It had a nice fragrance and well designed bottle”

· “Made it easy to brush hair afterwards”

· “Nice and light”

· “Non greasy”

· “Doesn’t stain when spilt”

· “It had a nice smell”

· “Smelt quite luxurious”

· “The shine it gave my hair”

· “All good, liked that it didn’t smell much”

· “Not too sure”

· “Made hair softer”

· “The condition it gave”

· “The bottle”

· “The fragrance”

· “Had a nice soft fragrance”

· “Smell was very good”

· “Gave good shine”

Q3b- What did you like least about the product?

· “All good”

· “I needed to apply lots”

· “Nothing”

· “Felt a bit oily at first”

· “Hair sometimes felt a little too brittle”

· “Hair wasn’t easy to style afterwards”

· “Nothing”

· “Felt greasy on my fingers”

· “Bit runny”

· “No fragrance”

· “Watery”

· “Didn’t seem to do much for my hair”

· “Made my hair greasy”

· “Nothing”

Question 4:

RIGHT SIDE (Reseed® Serum): Please list any other observations that you may have noticed during or after

Page 9: RESEED® PRESENTATION - AEPC UK Ltd. Clinical Trial Presentation.pdf · R12 TRI PEPTIDE ACTIVE HAIR SERUM: 30ml ... SPQ (Self-Assessment Questioner) Results Over 8 Week Period -Subjects

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use:

· “Hair became surprisingly thick after a few uses”

· “Shampoo excellent. Not sure which serum I preferred”

· “Very good”

· “Did make my hair itch a bit”

· “Ruined usual hair style

· “Pleased with the condition”

· “Softer, greater body, manageable”

· “I think it may have grown longer”

· “Very shine fragrance very good”

· “Good shine after use”

· “More bounce and volume”

· “Soft and manageable”

· “Good feel, easy to brush”

· “Refreshing and cool”

LEFT SIDE (Placebo): Please list any other observations that you may have noticed during or after use:

· “Did make my hair itch a bit”

· “Sticky”

· “Pleased with the condition”

· “Softer, more body”

· “Shampoo excellent. Not sure which serum I preferred”

· “Very shiny, fragrance very good”

· “Smells very nice”

· “Good product, hair felt soft and conditioned”

· “Average”

Question 5:

What aspect of the product would you improve?

· “None, I was very pleased”

· “Make it stay more moist for longer”

· “Maybe have it a different colour”

· “Dropper”

· “Would have a pump dispenser”

· “Not sure”

· “The way its applied, don’t like the dropper”

· “None, its ok as it is”

· “All ok, nothing to improve on”

Page 10: RESEED® PRESENTATION - AEPC UK Ltd. Clinical Trial Presentation.pdf · R12 TRI PEPTIDE ACTIVE HAIR SERUM: 30ml ... SPQ (Self-Assessment Questioner) Results Over 8 Week Period -Subjects

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- Clinical Test & Approval

CLINICALLY TESTED & APPROVED BY DERMATEST www.dermatest.de

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- Photos

Photos from documented results: Subject 24 clinical trials from Sept 2013 to Nov 2014

Sub 24

Day 14 Placebo

Sub 24

Day 14 Serum

Sub 24

Day 0 Left

Sub 24

Day 0 Right

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Sub 24 Day 56 placebo

Sub 24

Day 56 Serum

Sub 24

Day 42 Placebo

Sub 24

Day 42 Serum

Sub 24

Day 28 Placebo

Sub 24

Day 28 Serum

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Extended study of Subject 24 for 4 weeks (Feb 2014) using the Placebo and Serum

Sub 24 after 8 weeks Left Side Profile

Sub 24 after 8 weeks Left Side Profile

Sub 24 after 0 week Frontal Profile

Sub 24: 0 week Birdseye View

Sub 24: 0 week Placebo Side Profile

Sub 24: 0 week Serum Side Profile

Page 14: RESEED® PRESENTATION - AEPC UK Ltd. Clinical Trial Presentation.pdf · R12 TRI PEPTIDE ACTIVE HAIR SERUM: 30ml ... SPQ (Self-Assessment Questioner) Results Over 8 Week Period -Subjects

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Sub 24: after 2 weeks Frontal Profile

Sub 24: 2 weeks Birdseye View

Sub 24: 2 weeks Placebo Side Profile

Sub 24: after 2 weeks Serum Side Profile

Page 15: RESEED® PRESENTATION - AEPC UK Ltd. Clinical Trial Presentation.pdf · R12 TRI PEPTIDE ACTIVE HAIR SERUM: 30ml ... SPQ (Self-Assessment Questioner) Results Over 8 Week Period -Subjects

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Sub 24: after 4 weeks Frontal Profile

Sub 24: 4 weeks Birdseye view

Sub 24: 4 weeks Placebo Side Profile

Sub 24: after 4 weeks Serum Side Profile

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5. Ingredients List

RESEED Active Ingredients Product Surfactants Extract/Oil Preservative Active/Vitamin Rheology

Modifiers Fragrance

Products Name

Surfactant System

Extract/Oil Preservative

Active/Vitamin Rheology Modifiers

Fragrance

R8 Hair Solution (Men)

__________

Saw palmetto Extract

Rosemary Extract

Rommance Chamomile Extract

Fennel Extract

German Chamomile Extract

Nettle Extract

Horsetail Extract

Thyme Extract

Paraben Free PG -Free

________________

_______ Fragrance-

Free

R8 Hair Solution (Women)

_________

Arnica Montana Flower Extract

Rosemary Extract

Rommance Chamomile Extract

Green Tea Extract

German Chamomile Extract

Fennel Extract

Nettle Extract

Horsetail extract

Thyme extract

Paraben Free PG -Free

________________

_______ Fragrance-

Free

Sabal & Neem

Fortifying Shampoo

(Men)

Cocamide MEA

TEA-Lauryl Sulfate

Ammonium Lauryl Sulfate

Ammonium Laureth Sulfate

Neem Extract

Saw Palmetto extract

Paraben Free PG--Free

Vitamin B6

Vitamin F

Vitamin E

Vitamin B5

Zinc gluconate

Polyquaternium 10

Amodimethicone

Sodium chloride

Sabal & Ginkgo

Fortifying Shampoo (Women)

Cocamide MEA

TEA-Lauryl Sulfate

Ammonium

Lauryl Sulfate

Ammonium

Laureth

Sulfate

Ginkgo Biloba Extract

Saw Plametto Extract

Paraben Free PG--Free

Vitamin B6

Vitamin F

Vitamin E

Vitamin B5

Zinc gluconate

Polyquaternium 10

Amodimethicone

Sodium chloride

R12 Hair Serum (Men)

__________

Maca Extract

Mulberry extract

Sawpalmetto extract

Swertia extract

Ginseng extract

Paraben Free PG--Free

Isochrysis Galbana Extract

Zinc Gluconate Apigenin Biotinoyl Tripeptide-1

Niacinamide

Pyridoxine Hydrochloride

Dexpanthenol

__________ Fragrance-

Free

R12 Hair Serum

(Women) __________

Maca Extract

Mulberry extract

Paraben Free PG--Free

Isochrysis Galbana Extract __________

Fragrance-Free

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Sawpalmetto extract

Swertia extract

Ginseng extract

Zinc Gluconate Apigenin Biotinoyl Tripeptide-1

Niacinamide

Pyridoxine Hydrochloride

Dexpanthenol

Wheat Bran Ultra Volume Conditioner

with Pomegranate

(Women)

__________

Punica Granatum (pomegranate) Extract,

Silicone Quaternium-22

Paraben Free PG--Free

Sodium PCA, Sodium L-Pyrrolidone Carboxylate, Sodium Lactate, L-Arginine, L-Aspartic acid, L-Pyrrolidonecarboxylic acid, Glycerin, L-Alanine, L-Serine, L-Valine, L-Proline, L-Threonine, L-Isoleucine, L-Histidine, L-Phenylalanine

Panthenyl Hydroxypropyl Steardimonium Chloride

__________

Wheat Bran Ultra Volume Conditioner

with Hydrolysed Silk (Men)

__________ Extrapon Silk Milk

Wheat germ protein

Paraben Free PG--Free

__________

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6. Hair Supplements

- R21 Micro-Nutrients

R21 Micro-Nutrients

An Effective Hair Support Formula (Unisex)

WITH HAIR ESSENTIALS

SELENIUM, COPPER, ZINC, IRON & BIOTIN

MSM (Methylsulfonylmethane): acts as a natural sulphur source; feeds the hair from the inside out and helps

to support healthy hair.

Paardenstaart (Equisetum arvense): For skin health - improves skin, hair and nail condition, strengthens hair

and promotes growth.

Selenium: contributes to the maintenance of normal hair, EU approved claim 2010;8(10):1727, ID Nr; 281.

Copper: contributes to the maintenance of normal hair pigmentation, EU approved claim 2009;7(9):1211 ID Nr;

268, 1724.

Pantothenic Acid: properties are - energy-yielding metabolism assists in mental performance, synthesis and

metabolism of vitamin D and some neurotransmitters, reduction of tiredness and fatigue, Commission

Regulation (EU) 432/2012 of 16/05/2012.

Biotin: contributes to the maintenance of normal hair, EU approved claim 2009;7(9):1209, 2010;8(10) ID Nr;

1728 118, 121 and 2876.

Folic Acid, Carbonate, Citrate, Manganese & Silicon: important elements in maintaining healthy body

functions.

Iron, Manganese, Vitamins A, B1, B2, B6, B12, C, D, D3 & E: contributes towards maintaining normal healthy

body functions and assists in skin, hair and nail conditions.

Zinc: contributes to the maintenance of normal hair. EU approved claim 2010;8(10):1819 ID Nr; 412.

Para-Aminobenzoic Acid: can help maintain hair, nails and skin in optimum condition.

Choline: may improve hair thickness - helps maintain hair strength, hair elasticity, improve hair volume and

maintain healthy hair.

L-Cysteine: Sulphur-containing amino acids could contribute to the maintenance of healthy hair structure, nails

and skin.

L-Methionine: could increase hair and promote their growth.