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RESPIRATORY VIRUS SURVEILLANCE REPORT Wisconsin Department of Health Services | Division of Public Health Bureau of Communicable Diseases | Communicable Diseases Epidemiology Secon www.dhs.wisconsin.gov/dph/bcd.htm | [email protected] Week 52: Ending December 28, 2019 P-02346

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Page 1: RESPIRATORY VIRUS SURVEILLANCE REPORT · 2020-01-03 · AT-A-GLANCE: Weekly Respiratory Report Description ... Respiratory virus Tested Positive (n) Positive (%) RSV 1746 421 24.1%

RESPIRATORY VIRUS SURVEILLANCE REPORT

Wisconsin Department of Health Services | Division of Public Health

Bureau of Communicable Diseases | Communicable Diseases Epidemiology Section

www.dhs.wisconsin.gov/dph/bcd.htm | [email protected]

Week 52: Ending December 28, 2019

P-02346

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Page 2

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

STATE OF WISCONSIN REGION V OF US

(WI, MN, IL, MI, OH, IN)

UNITED STATES

ILI: BELOW BASELINE ILI: HIGH LEVELS ILI: MODERATE LEVELS

INFLUENZA-ASSOCIATED

PEDIATRIC DEATHS REPORTED:

INFLUENZA LIKE ILLNESS (ILI) ACTIVITY

For National US influenza surveillance statistics visit: www.cdc.gov/flu/weekly/

Week 52, 2019

October 1, 2019 to present

Wisconsin 0 0

Nationwide 5 27

ILI: INSUFFICIENT DATA

AT-A-GLANCE:

Weekly Respiratory Report Description

Predominant Viruses of the Week: Influenza B and RSV are the predominant viruses this week.

CURRENT ALERTS:

Influenza B (Victoria lineage) continues to be

the predominant influenza virus in Wisconsin.

Influenza B viruses cause increased morbidity

among the younger population.

155 influenza-associated hospitalizations were

reported last week.

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Page 3

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

Influenza and Pneumonia Deaths, Wisconsin

INFLUENZA AND PNEUMONIA-ASSOCIATED MORTALITY

Influenza- and pneumonia-associated deaths by influenza season year and week, Wisconsin

Influenza season week

Influenza-

associated

deaths (I)

Pneumonia-

associated

deaths (P)

Percent I+P of

all deaths

Baseline I+P

of all deaths

Threshold I+P

of all deaths

50 2 54 5.3% 5.4% 6.1%

51

1 75 8.9% 5.5% 6.2%

52

(Preliminary data) 0 27 6.9% 5.6% 6.3%

Seasonal total 11 798 4.9% NA NA

Data source: DPH, Office of Health Informatics

Influenza- and pneumonia-associated deaths by most recent influenza season week,

Wisconsin, 2019-2020 season

3%

4%

5%

6%

7%

8%

9%

10%

11%

201

6-4

0

201

7-0

2

201

7-1

6

201

7-3

0

201

7-4

4

201

8-0

6

201

8-2

0

201

8-3

4

201

8-4

8

201

9-1

0

201

9-2

4

201

9-3

8

Percent of deaths associated with

influenza and pneumonia

Influenza season year-week

Percent of deaths associated with influenza and pneumonia Baseline Threshold

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Page 4

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

Wisconsin positive influenza results and subtypes by PCR

Cumulative number of positive influenza PCR tests by subtype September 1, 2019 to present

WISCONSIN LABORATORY SURVEILLANCE

FOR RESPIRATORY VIRUSES BY PCR

0%

5%

10%

15%

20%

25%

0

300

600

900

1,200

1,500

8/24 9/21 10/19 11/16 12/14 1/11 2/8 3/7 4/4 5/2

% P

osi

tive

by

PC

R

Nu

mb

er o

f po

siti

ve d

ete

ctio

ns

Week ending

A (unknown subtype) A (H3N2 seasonal) A (H1N1) A (H3N2v)

B (unknown subtype) B (Victoria) B (Yamagata) Influenza % positive

30% 70%

A (2009 H1N1) A (H3N2) A (Unknown) B (Victoria) B (Yamagata) B (Unknown)

Total positive (n) 58 47 813 88 8 2078 3092

% of total positive 2% 2% 26% 3% 0% 67% 100%

Influenza A: Influenza B:Total

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Page 5

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

Trends in respiratory virus activity by PCR

WISCONSIN LABORATORY SURVEILLANCE FOR

RESPIRATORY VIRUSES BY PCR

Respiratory virus Tested Positive

(n)

Positive

(%)

Influenza A Influenza B

H3N2 2009 H1N1 Unknown Victoria Yamagata Unknown

Influenza 5433 1161 21.4% 3 10 335 10 0 794

Respiratory virus Tested

Positive

(n)

Positive

(%) Parainfluenza 1 Parainfluenza 2 Parainfluenza 3 Parainfluenza 4

Parainfluenza 800 29 3.6% 8 1 0 20

Respiratory virus Tested Positive Positive CoV 229E CoV OC43 CoV NL63 CoV HKU1

Coronavirus (CoV) 388 20 5.2% 0 0 1 19

Respiratory virus Tested Positive (n) Positive (%)

RSV 1746 421 24.1%

Human metapneumovirus 821 42 5.1%

Rhino-enterovirus 808 66 8.2%

Adenovirus 388 9 2.3%

Week 52: Ending on December 28, 2019

0%

5%

10%

15%

20%

25%

30%

11/23 11/30 12/7 12/14 12/21 12/28

% P

osi

tive

by

PC

R (3

-we

ek

mo

vin

g av

era

ge)

Week ending

― Influenza― RSV― hMPV- - Rhino-Entero― Adenovirus- - Parainfluenza- - Coronavirus

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Page 6

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

WISCONSIN STATE SUMMARY

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

1181 109 149 258 21.8% 268 71 26.5% 3.9% 2.4% 3.6%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

0%

5%

10%

15%

20%

25%

30%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

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Page 7

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

WISCONSIN STATE SUMMARY

ILI activity trend analysis by influenza season, Wisconsin

Influenza-associated hospitalizations, Wisconsin Electronic Disease Surveillance System

September 1, 2019 to present

Reported cumulative influenza-associated hospitalizations by influenza season, Wisconsin

A (2009

H1N1)

A

(H3N2)

A

(Unknown)B

Not

reported

<1 13 1 0 2 8 2 3 1 0 0

1-4 35 0 0 9 19 7 7 2 0 0

5-17 41 2 0 5 21 13 4 1 0 0

18-49 105 4 1 27 46 27 18 6 8 2

50-64 98 9 4 43 31 11 15 4 0 0

65+ 167 6 12 83 58 8 17 2 0 0

Total 459 22 17 169 183 68 64 16 8 2

Postpartum

(≤6 weeks)

Age group

(years)

Total

reported

(n)

Influenza subtypeAdmitted

to ICU

Required

mechanical

ventilation

Pregnant

0

200

400

600

800

44 45 46 47 48 49 50 51

Infl

ue

nza

-ass

oci

ate

d

ho

spit

aliz

ati

on

s, c

um

ula

tive

(n

)

Influenza season week

2015-2016

2016-2017

2017-2018

2018-2019

2019-2020

0%

1%

2%

3%

4%

5%

6%

40 42 44 46 48 50 52 2 4 6 8 10 12 14 16 18 20

Ave

rage

% I

LI (3

-wee

k m

ovi

ng

ave

rage

)

Influenza season week

― 2015-16- - 2016-17- - 2017-18― 2018-19― 2019-20

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Page 8

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

NORTHEASTERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

339 32 22 54 15.9% 111 30 27.0% 3.2% 2.6% 4.0%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

0%

5%

10%

15%

20%

25%

30%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

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Page 9

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

NORTHWESTERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

505 53 86 139 27.5% 123 32 26.0% 2.7% 1.9% 3.2%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

0%

5%

10%

15%

20%

25%

30%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

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Page 10

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

SOUTHEASTERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

312 18 36 54 17.3% 26 7 26.9% 4.0% 2.9% 4.1%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

0%

5%

10%

15%

20%

25%

30%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

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Page 11

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

SOUTHERN REGION

ILI activity trend analysis

Influenza and RSV trend analysis

Influenza rapid antigen tests RSV rapid antigen tests Influenza-like illness (ILI)

Tested Positive (n)

% Positive Tested Positive (n) % Positive ILI % Baseline Threshold Influenza A Influenza B Total

25 6 5 11 44.0% 26 7 26.9% 5.4% 2.1% 3.2%

0%

1%

2%

3%

4%

5%

6%

7%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

Ave

rage

% I

LI

Week ending

Baseline Threshold 3 per. Mov. Avg. (Average % ILI)

0%

5%

10%

15%

20%

25%

30%

35%

40%

45%

50%

9/1 9/22 10/13 11/3 11/24 12/15 1/5 1/26 2/16 3/8 3/29 4/19 5/10 5/31

% P

osi

tive

by

an

tige

n d

etec

tio

n

Week ending

3 per. Mov. Avg. (RSV) 3 per. Mov. Avg. (Influenza)

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Page 12

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

Influenza vaccine composition 2019-2020:

The trivalent vaccines for use in the 2019-2020 influenza season contain the following:

A/Brisbane/02/2018 (H1N1)pdm09–like virus (updated)

A/Kansas/14/2017 (H3N2)-like virus (updated) B/Colorado/06/2017-like (Victoria lineage) virus

It is recommended that quadrivalent vaccines containing two influenza B viruses contain the above three viruses and:

B/Phuket/3073/2013-like virus (Yamagata lineage)

Cumulative percentage of Wisconsin residents who received 1 or more doses of

influenza vaccine, 2019-2020 influenza season

SEASONAL INFLUENZA VACCINATION

Data source: All influenza vaccination rates presented were calculated using data from the Wisconsin

Immunization Registry (numerator) and Wisconsin population estimates (denominator).

37%

40%

70%

0% 50% 100%

This season so far

2018-19 Total Vaccinated

Healthy People 2020 GoalHealthy People 2020 Goal

2018-2019Total Vaccinated

2019-2020 as of 12/28/2019

During this week, the vaccination rates for the 2019-2020 influenza vaccine season have been above the vaccination rates observed

during the 2018-2019 season.

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Page 13

Division of Public Health Respiratory Virus Surveillance Report Week 52: Ending December 28, 2019

SEASONAL INFLUENZA VACCINATION

Percentage of Wisconsin residents who received one or more doses of influenza

vaccine, by age group and influenza season

Each season includes doses administered during the same time period (August 1 through May 3).

Percentage of Wisconsin residents who received one or more doses of influenza

vaccine, by race and ethnicity and region, 2019-2020 influenza season

Southeastern Western Southern

22%

27%

20%

33%

23%

34%

37%Total

Non-Hispanic

Hispanic

White

Black

Asian

American Indian/

Alaska-Native

All of Wisconsin Northeastern Northern

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

0 years 1 to 4 years 5 to 17 years 18 to 49 years 50 to 64 years 65 years plus All Ages

2015-2016 2016-2017 2017-2018 2018-2019 2019-2020 as of current week

27%

25%

20%

35%

24%

36%

37%

22%

26%

18%

32%

22%

33%

35%

18%

26%

18%

34%

24%

35%

36%

27%

29%

20%

32%

24%

33%

41%

12%

27%

21%

32%

22%

33%

34%