retension and hiv testing christine khosropour

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Christine Khosropour, MPH Rollins School of Public Health Emory University April 1, 2011 Sex::Tech Conference San Francisco, CA

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“Retention and HIV testing of MSM enrolled in a 12-month online study” was presented at Sex::Tech 2011 by Christine Khosropour, MPH of Rollins School of Public Health Emory University.

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Page 1: Retension and HIV Testing Christine Khosropour

Christine Khosropour, MPHRollins School of Public Health

Emory University

April 1, 2011Sex::Tech Conference

San Francisco, CA

Page 2: Retension and HIV Testing Christine Khosropour

Online HIV prevention intervention study design

Experience with at-home HIV testing as part of an online study

Difference in participant retention by follow-up method

Page 3: Retension and HIV Testing Christine Khosropour

Diagnoses of HIV Infection among Adults and Adolescents, 2005-2008

37 States and 5 US Dependent Areas

Centers for Disease Control and Prevention: http://www.cdc.gov/hiv/topics/surveillance/index.htm

Page 4: Retension and HIV Testing Christine Khosropour

CDC rating of HIV prevention studies rated on scientific evidence of efficacy: 41 classified as ‘best evidence’

9 proven to be efficacious with MSM

Internet-based interventions Difficult to follow same criteria as ‘real-

word’ interventions

Page 5: Retension and HIV Testing Christine Khosropour

CDC ‘best-evidence’ HIV prevention intervention criteria:

Prospective design Biological outcomes Adequate retention (> 70%) Adequate representation of racial/ethnic

minorities

Page 6: Retension and HIV Testing Christine Khosropour

CDC ‘best-evidence’ HIV prevention intervention criteria:

Prospective design Biological outcomes Adequate retention (> 70%) Adequate representation of racial/ethnic

minorities

Page 7: Retension and HIV Testing Christine Khosropour
Page 8: Retension and HIV Testing Christine Khosropour

Click-through banner ad

Screening Questions

Consent

Black

Online FU

SMS FU Bi-monthly FU

Month 12 Online Survey

Baseline Online Survey

Baseline HIV TestBaseline HIV Test

Month 12 HIV Test

Month 12 HIV Test

Bi-monthly FU

White

Online FU

SMS FU Bi-monthly FU

Month 12 Online Survey

Baseline Online Survey

Baseline HIV TestBaseline HIV Test

Month 12 HIV Test

Month 12 HIV Test

Bi-monthly FU

Hispanic

Online FU

SMS FU Bi-monthly FU

Month 12 Online Survey

Baseline Online Survey

Baseline HIV TestBaseline HIV Test

Month 12 HIV Test

Month 12 HIV Test

Bi-monthly FU

INTERVENTION

INTERVENTION

Page 9: Retension and HIV Testing Christine Khosropour
Page 10: Retension and HIV Testing Christine Khosropour

Click-through banner ad

Screening Questions

Consent

Black

Online FU

SMS FU Bi-monthly FU

Month 12 Online Survey

Baseline Online Survey

Baseline HIV TestBaseline HIV Test

Month 12 HIV Test

Month 12 HIV Test

Bi-monthly FU

White

Online FU

SMS FU Bi-monthly FU

Month 12 Online Survey

Baseline Online Survey

Baseline HIV TestBaseline HIV Test

Month 12 HIV Test

Month 12 HIV Test

Bi-monthly FU

Hispanic

Online FU

SMS FU Bi-monthly FU

Month 12 Online Survey

Baseline Online Survey

Baseline HIV TestBaseline HIV Test

Month 12 HIV Test

Month 12 HIV Test

Bi-monthly FU

Page 11: Retension and HIV Testing Christine Khosropour
Page 12: Retension and HIV Testing Christine Khosropour

Black

White

Hispanic

73% Return(115)

85% Return(482)

79% Return(139)

897 Kits

157

564

176

82% Return(736)

3% HIV-Positive(24)

7.8% Positive(9)

2.3% Positive(11)

2.9% Positive(4)

17.5%

62.9%

19.6%

Page 13: Retension and HIV Testing Christine Khosropour
Page 14: Retension and HIV Testing Christine Khosropour

Click-through banner ad

Screening Questions

Consent

Black

Online FU

SMS FU Bi-monthly FU

Month 12 Online Survey

Baseline Online Survey

Baseline HIV TestBaseline HIV Test

Month 12 HIV Test

Month 12 HIV Test

Bi-monthly FU

White

Online FU

SMS FU Bi-monthly FU

Month 12 Online Survey

Baseline Online Survey

Baseline HIV TestBaseline HIV Test

Month 12 HIV Test

Month 12 HIV Test

Bi-monthly FU

Hispanic

Online FU

SMS FU Bi-monthly FU

Month 12 Online Survey

Baseline Online Survey

Baseline HIV TestBaseline HIV Test

Month 12 HIV Test

Month 12 HIV Test

Bi-monthly FU

Page 15: Retension and HIV Testing Christine Khosropour
Page 16: Retension and HIV Testing Christine Khosropour
Page 17: Retension and HIV Testing Christine Khosropour
Page 18: Retension and HIV Testing Christine Khosropour

89%(327/367)

92%(317/345)

Overall Retention

90%(644/712)

SMS

Online

Page 19: Retension and HIV Testing Christine Khosropour

Black

White

Hispanic

84%(89/106)

93%(436/471)

88%(119/135)

75%(45/60)

96%(44/46) 93%

(225/242)

92%(211/229)

88%(57/65)

89%(62/70)

Online

SMS

Overall Retention:90%

Page 20: Retension and HIV Testing Christine Khosropour

Month 4

90%(250/277)

92%(198/215)

94%(192/205)

SMS

Online

Overall Retention

93%(390/420)

Month 6

Overall Retention

Page 21: Retension and HIV Testing Christine Khosropour

Successes: Over 80% of participants returned an at-home

HIV test Biological outcome = estimated HIV

incidence

90% of participants retained at first follow-up High retention (>70%) = can assess

outcomes Difference in retention by race/ethnicity =

different methods for data collection

Next step: Design an Intervention!

Page 22: Retension and HIV Testing Christine Khosropour

Research participants Patrick Sullivan, DVM, PhD Nicole Luisi, MPH Cyclogram Emory Center for AIDS Research

(CFAR) P30 AI050409

NIH, National Center on Minority Health and Health Disparities Grant # 1RC1MD004370-01

Page 23: Retension and HIV Testing Christine Khosropour