reviewers, volume 10 (1996)

Reviewers, Volume 10" (1996) The editors would like to thank the Editorial Board and the following scientists who were kind enough to review papers and provide advice during 1996.

*From October 18, 1995 to October 17, 1996

Adler, Paul Allshire, Robin Ah, Fred Alwine, James Ammerer, Gustave Anderson, David Anderson, Kathryn Anderson, Phillip Andrews, Brenda Ares, Manuel Amdt, Kim Artavanis-Tsakonas,

Spyridon Artzt, Karen Ashburner, Michael Austin, Stuart Ausubel, Frederick Avery, Leon Avner, Philip Baker, Tania Baldwin, Albert, Jr. Baltimore, David Bannerjee, Utpal Banuett, Flora Barbacid, Mariano Bardwell, James Bargmann, Cori Barlow, Denise Barres, Barbara Bartolomei, Marisa Barton, Mary K. Basler, Konrad Bate, Michael Beach, David Beato, Miguel Becker, Peter Beddington, Rosa Beggs, Jean Behringer, Richard Bell, Steve Benezra, Robert Benson, Spencer Berget, Susan Berk, Arnold Bemards, Rene Bernstein, Alan Berry, Marla Besmer, Peter Beug, Hartmut Bickmore, Wendy Bienz, Marianne Bier, Ethan Bingham, Paul Bird, Adrian

Bishop, Douglas Black, Douglas Blackwell, Keith Blobel, Gunter Blumenthal, Thomas Bock, August Bodmer, Rolf Boeke, Jeff Bohmann, Dirk Bolen, Joseph Botchan, Michael Bothwell, A1 Bouck, Noel Brady, Scott Brandriss, Marjorie Bravo, Rodrigo Brent, Rodger Brewin, Nick Brockdroff, Neil Buckingham, Margaret Buratowski, Stephen Burden, Steven Burgoyne, Paul Burley, Stephen Butler, Mark Cantley, Lewis Capecchi, Mario Carey, Michael Carlson, Marian Carr, Anthony Carroll, Sean Cashmore, Tony Cedar, Howard Chandler, Vicki Chant, John Chater, Keith Chen, Jasmine Cho, Ken Chorey, Joanne Clayton, David Cleary, Michael Coen, Donald Coffin, John Cole, Charles Collins, Kathy Cooley, Lynn Corces, Victor Corey, Suzanne Costantini, Frank Courey, Albert Crabtree, Gerald Craig, Elizabeth Craig, Nancy Cross, Frederick Damsky, Caroline Dangl, Jeff Darnell, James Darnell, Robert Davies, Kay de Lange, Titia Deng, Xiong-W DeRobertis, Eddy Desplan, Claude Dixit, Vishva

Donahue, Thomas Donehower, Lawrence Draetta, Giulio Dreyfuss, Gideon Driever, Wolfgang Drubin, David Duboule, Denis Dunn, Ashley Dunphy, William Dynlacht, Brian Dyson, Nicholas Dzierzak, Elaine Ebright, Richard Eisenman, Robert Elgin, Sally Elion, Elaine Emerson, Beverly Engel, Douglas Ephrussi, Anne Errington, Jeffrey Ewen, Mark Farmer, Stephen Fearon, Eric Felsenfeld, Gary Firtel, Richard Fishman , Mark Flavell, Richard Franke, Werner Frasch, Manfred Freedman, Len Freidberg, Errol Friend, Stephen Fuchs, Elaine Furuya, Masaki Gall, Joseph Galloway, Denise Geiduschek, Peter Gerace, Larry Gibbs, Clarence Gilman, Michael Glass, Christopher Glover, David Gober, James Goff, Stephen Gold, Lawrence Goldfarb, Mitchell Goldstein, Joseph Goodman, Richard Gordon, Colin Gorovsky, Martin Gottschling, Daniel Grabowski, Paula Gralla, Jay Graves, Barbara Green, Michael Greenblatt, Jack Greenwald, Iva Greider, Carol Gridley, Thomas Griep, Anne Groner, Bernard Grossman, Alan Grummt, Ingrid Grunstein, Michael

GENES & DEVELOPMENT 3219

Gruss, Peter Guthrie, Chris Haber, lames Hahn, Steven Hake, Sarah Hall, Alan Hanahan, Doug Hannon, Gregory Hannun, Yosef Hargreaves, lohn Harper, Wade Harrison, Stephen Hartenstein, Volker Haselkorn, Robert Hauschka, Stephen Hawley, Scott Hayday, Adrian Hearing, Patrick Hengartner, Michael Henikoff, Steve Hernandez, Nouria Herskowitz, Ira Higgs, Doug Hill, Robert Hinnebusch, Alan Hinton, Barry Hirano, Tatsuya Hoch, James Hoeijmakers, lan Hoffman, Michael Hogan, Brigid Holder, Nigel Holmgren, Robert Hope, Ian Howley, Peter Hoyt, Andrew Hughes, Steve Hunter, Tony Hurt, Edward Hurwitz, lerard Hyman, Linda Hynes, Richard Ihle, James Ingraham, Holly Ish-Horowicz, David Jacks, Tyler Jackson, Ian Jackson, Stephen lacobson, Alan lackle, Herbert Jaenisch, Rudolph Jentsch, Stefan lessen, Kristijian Johnson, Gary Johnson, Peter Johnson, Reid Johnston, Lee Johnston, Mark Jones, Katherine loyner, Alexandra lurgens, Gerd Kahmann, Regine Kalderon, Dan Kaplan, Jerry Karpen, Gary Kastan, Michael

Kaufman, Paul Keller, Walter Kenyon, Cynthia Kessin, Richard Kidwell-Brown, Margaret Kim, Stuart Kimelman, David Kimmel, Alan Kimmel, Charles Kingsley, David Kingston, Robert Kintner, Christopher Klein, Hannah Kolodner, Richard Konderosi, Adam Konopka, James Koopman, Peter Korsmeyer, Stanley Kowalcykowski, Stephen Krainer, Adrian Krasnow, Mark Krumlauf, Robb Kustu, Sydney Lamond, Angus Landy, Art Lane, Daniel Lane, David Lassar, Andrew Lazenbnik, Yuri Leavitt, Andrew Leder, Phil Lee, David Lees, Jackie Lehmann, Alan Lehner, Christian Lemke, Greg Leptin, Maria Levin, David Levine, Arnold Levy, David Lewis, Susanna Lis, John Losick, Richard Lovell-Badge, Robin Lowe, Scott Lowry, Douglas Luhrmann, Reinhard Lustig, Art Lyon, Mary Maas, Richard MacDonald, Paul MacLeod, K. Maizels, Nancy Mak, Tak Malim, Michael Mangelsdorf, David Maniatis, Tom Mann, Jeffrey Marshall, Chris Martin, David Massague, Joan Mathews, Michael Mattaj, Iain Matthias, Patrick Meinke, David Melton, Doug

Mendenhall, Michael Miller, Lois Mirsky, Rhona Mitchell, Aaron Mizuuchi, Kiyoshi Mlodzik, Marek Model, Peter Modolell, Juan Mohun, Tim Moon, Randall Moore, Melissa Morimoto, Richard Moses, Harold Moses, Kevin Moss, Tom Murray, Andrew Murre, Cornelius Nabel, Gary Nasmyth, Kim Neuberger, Michael Neufeld, Elizabeth Nevins, Joseph Newlon, Carol Newman, Andrew Newport, John Nilsen, Timothy Niswander, Lee Nomura, Masayasu Nurse, Paul Nusse, Roel O'Farrell, Patrick Olson, Eric Oren, Moshe Orkin, Stuart Orr-Weaver, Terry Pabo, Carl Pace, Norman Parker, Malcolm Parker, Peter Parker, Roy Parkinson, Sandy Paro, Renato Parslow, Tristan Pavletich, Nikola Pendergast, Ann Marie Perlman, Philip Perlmann, Thomas Perrimon, Norbert Peterson, Craig Pfahl, Magnus Phillips, Simon Pillus, Lorraine Poellinger, Lorenz Polakis, Paul Posakony, James Priess, James Pringle, John Proudfoot, Nicholas Ptashne, Mark Pugh, B. Franklin Quail, Peter Rabbitts, Terry Raff, Martin Rajewsky, Klaus Ramakrishnan, Venki Reed, Robin

3220 GENES & DEVELOPMENT

Reed, Steve Reeder, Ronald Reik, Wolf Reinberg, Danny Reines, Daniel Reznikoff, William Rice, Andrew Rigby, Peter Rine, Jasper Rio, Donald Roberts, James Robertson, Elizabeth Roeder, Robert Rong, Li Roop, Dennis Rorschneider, Lawrence Rosbash, Michael Rose, Mark Rosenberg, Naomi Rosenfeld, M. Geoff Rossant, Janet Rushlow, Christine Russell, Marjorie Russell, Paul Ruvkun, Gary Rymond, Brian Sachs, Alan Sandmeyer, Suzanne Sanes, Josh Sarnow, Peter Schechter, Alan Schedl, Andreas Schedl, Paul Schedl, Timothy Schlessinger, Joseph Sch6pbach, Trudi Schwab, Martin Schwarz-Sommer,

Zsuzsanna Scott, Matthew Semenza, Gregg Shackleford, Gregory Shilo, Ben-Zion Shimkets, Lawrence Shimura, Yoshiro Shore, David Siebenlist, Ulrich Sigler, Paul Silhavy, Thomas Silver, Pamela Simons, Kai Simpson, Patricia Simpson, Robert Singh, Harinder Sive, Hazel Skene, Barbara Skowronski, Jacek Slack, Jonathan Smale, Steven Smith, Jim Smith, Mitchell Snyder, Michael Sollner-Webb, Barbara Sorger, Peter Speck, Nancy Speigelman, Bruce

Spradling, Allan Sprague, George St. Johnston, Daniel Stadtman, Theresa Stark, Mike Staskawicz, Brian Stellar, Hermann Stenlund, Arne Sternberg, Paul Sternglanz, Rolf Stillman, Bruce Strasser, Andreas Strickland, Sidney Struhl, Gary Struhl, Kevin Studer, Michelle Stunnenberg, Henk Surani, Azim Tessier-Lavignc, Marc Thomas, Christopher Thompson, Craig Thummel, Carl Tollervey, David Tomlinson, Andrew Treisman, Richard Tryggvason, Karl Tye, Bik-Kwoon Ullu, Elizabetta Van Aelst, Linda Van Dyke, Terry van Heyningen, Veronica Varmus, Harold Vennstrom, Bjom Verma, Inder Vogt, Peter Wagner, Erwin Wahl, Geoffrey Walbot, Virginia Wasserman, Steven Weber, Klaus Weigel, Detlef Weinberg, Robert Weinert, Ted Weissman, Charles Weissman, irving Wensink, Peter West, Stephen Westerfield, Monte Weston, Kathleen White, Eileen White, Rob Wickens, Marvin Wieczorck, Helmut Wieschaus, Eric Willison, Keith Winston, Fred Wisniewski, Henryk Witte, Owcn Wolffe, Alan Wong, Winnie Wood, Richard Wormington, Michael Wright, Christopher Yamamoto, Keith Yanagida, Mitsuhiro Yaniv, Moshe

Yanofsky, Martin Young, Richard Yuspa, Stuart Zakian, Virginia Ziff, Edward Zinn, Kai


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Author Index, Volume 10 (1996) Abrams, J.M., 1773 Adams, J.M., 70 Adler, H.8., 1455 Aebersold, R., 1084 Aguilar-Cordova, E., 553 Ahringer, J., 1120 Akimani, H., 528 Alarcon, C.M., 279 Alexandre. C., 2003 Alexandropoulos, K., 1341 Algate, P.A., 1084 Allende, M.L., 3141 Alley, M.R.K., 1532 Alwine, J.C., 325, 1369 Alzhanova-Ericsson, A.T.,

2881 Amano, S., 1724 Amberg, D.C., 1608 Ammerer, G., 129 Amsterdam, A., 3141 Anderson, J.E., 1173 Andresen, J.M., 2903 Andrew, D.J., 103 Apone, L.M., 2368 Arber, S., 289 Ares, M., Jr., 220 Arndt, K.T., 1904 Arroyo, E., 1751 Asano, M., 1422 Ashley, T., 2411, 2423 Assa-Munt, N., 16 Aubry, L., 118 Azpiazu, N., 3183 Badiani, P., 2732 Bagni, C., 1411 Bai, Y., 2025 Baker, J.C., 1880 Baltimore, D., 963, 1341,

2401, 2411 Banerjee, U., 1194 Barberis, A., 2359 Bardwell, L., 2831 Barolo, S., 3195 Barrett, T., 2732 Basson, M., 1953 Baumeister, R., 1395 Beach, D., 1633 Beall, E.L., 921 Beard, C., 1008 Beaulieu, N., 1930 Becker, T., 3141 Behringer, R.R., 2577 Beijersbergen, R.L., 2969 Beiman, M., 2993 Belfort, M., 351, 2158 Bentley, N.J., 2423 Berget, S.M., 208 Bergstrom, D.E., 1260 Berk, A.J., 2491 Bermingham, J.R., Jr., 1751 Bemards, R., 2969 Beug, H., 2462 Biehs, B., 2922 Bier, E., 2922

Birchmeier, C., 1184 Bitgood, M.J., 647 Blackburn, E.H., 1822 Blackman, R.K., 1260 Blakely, G., 762 Blatter, E.E., 16 B6hm, T., 1516 Boeke, J.D., 620 Bogue, M.A., 553 Boise, L.H., 2621 Bommakanti, M., 129 Bonten, E., 3156 Boscheron, C., 1796 Bossard, P., 1670 Bouhidel, K., 1812 Bowman, T., 826 Braincrd, E.E., 2411, 2423 Brass, A.L., 2335 Breitwieser, W., 2179 Brewer, B.J., 1595 Brill, S.J., 2222 Brissette, J.L., 2212 Broach, J.R., 382, 1021 Brodbeck, C., 2707 Brody, M.S., 2265 Bronson, R.T., 1621, 1633,

2055, 2411 Brook, A., 2505 Brown, J.D., 2805 Brown, S.A., 1479 Brun, R.P., 974 Bryant, G.O., 2491 Brzoska, P.M., 2564 Buck, S.W., 1297 Bullrich, F., 1724 Bunker, C.A., 905 Burgeson, R.E., 1724 Burke, T.W., 711 Burley, S.K., 2491 Burson, L.M., 887 Cairns, B.R., 2117, 2131 Camper, S.A., 313 Cannon, K., 37 Cao, J., 1049 Cao, Z., 37 Cardenas, M.E., 279 Carey, M., 2540, 2769 Carlberg, K., 1084 Carlson, M., 3105 Caroni, P., 289 Cart, A.M., 2423 Carthew, R.W., 2167 Castaho, I.B., 2564 Cate, R.L., 2577 Cech, T.R., 2870 Cepek, K.L., 2079 Chambon, P., 80, 2326 Chan, Y.R., 2055 Chang, H.C., 272 Chang, J., 777 Chao, D.T., 2859 Chasman, D.I., 2079 Chen, H., 2564 Chen, J., 974

Chen, J.-Y., 2326 Chen, P., 1773 Chen, P.-L., 2794 Chen, X., 2438 Chen, Y., 2794 Cheng, G., 963 Chi, T., 2540 Chin, W., 80 Chin-Sang, I.D., 2314 Christenson, E.R., 2423 Christiano, A.M., 1724 Christman, M.F., 2564 Chung, D., 3051 Clark, A.M., 118 Clarkin, K.C., 934 Cleghon, V., 566 Clurman, B.E., 1979 Clyman, J., 351 Cobrinik, D., 1633 Cocker, J.H., 1516 Coffer, P., 1455 Cohen, J.B., 338 Cohen, M., 129 Cohen-Fix, O., 3081 Cole, C.N., 1608 Coleman, J.R., 1670 Colot, H.V., 1699 Cook, J.G., 2831 Copeland, T.D., 566 Cornet, F., 1152 Cosgrove, D., 2981 Costantini, F., 154 Coursen, J.D., 1219 Crabtree, G.R., 2117 Craig, N.L., 2145 Crespo, P., 1455 Crompton, T., 948 Cygan, J.A., 1260 Daga, A., 1194 D'Agati, V.; 154 Dahanukar, A., 2610 Dai, P., 528 Damania, B., 1369 Daneholt, B., 2881 Danska, J.S., 2038 Darlington, G.J., 804 Dash, A.B., 1858 Datar, S.A., 1966 Dausman, J., 1008 Davis, R.J., 2732 d'Azzo, A., 3156 De Baere, I., 755 Decimo, D., 80 DeArmond, S.J., 1736 DeBoy, R.T., 2145 Decatur, A.L., 2348 Degenstein, L., 165 Deng, K., 1657 Denis, G.V., 261 Desbarats, L., 447 Devine, S.E., 620 Di Como, C.J., 1904 Di Cunto, F., 3065 Di Leonardo, A., 934

Dierich, A., 80 Diffley, J.F.X., 1516, 2819 Diller, J.D., 1595 Dodd, J.A., 887, 2551 Doe, C.Q., 3003 Doherty, D., 421 Dominski, Z., 3028 Donaldson, T., 2302 Donehower, L.A., 553 Dotto, G.P., 2212, 3065 Doucas, V., 196 Drouin, J., 1284 Du, W., 1206 Duboule, D., 2326 Dudek, H., 816 Dugich-Djordjevic, M.M.,

3129 Dull, M., 1382 Dumstrei, K., 1194 Dunphy, W.G., 1503 Duronio, R.J., 2505 Dyson, N., 1206, 1621, 1633,

2505 Eady, R.A.J., 1724 Eagelson, K., 1049 Ebright, R.H., 16 Eckhaus, M., 836 Eckner, R., 2478 Edgar, B.A., 1966 Edmondson, D.G., 1247 Eichele, G., 176 Eidemiller, J., 185 Eilers, M., 447 Eisenbeis, C.F., 2335 Elledge, S.J., 2632 Ellis, R., 974 Elmore, L., 1219 Endo, S., 1645 Ephrussi, A., 2179 Erdjument-Bromage, H., 1049 Errington, J., 794 Evans, R.M., 196, 974 Fangman, W.L., 1595 Fankhauser, C., 2707 Fantino, E., 887 Farihas, I., 1382 Farrell, S., 2359 Fay, D.S., 395 Feger, G., 421 Feld, R., 244 Ferguson, B.M., 1595 Ferguson, K.C., 1543 Fernandez-Salguero, P., 60 Feucht, A., 794 Field, D.J., 489 Fiering, S., 185 Filosi, N., 407 Finegold, M.J., 2577 Firtel, R.A., 118 Fischer, D., 1143 Fisher-Adams, G., 686 Fitzsimmons, D., 2198 Flaggs, G., 2423 Flesken-Nikitin, A., 1835


Foiani, M., 395 Forman, B.M., 974 Fornerod, M., 3156 Forrester, K., 1219 Fox, C.H., 60 Frampton, J., 2720 Francois, V., 2922 Frasch, M., 3183 Fraser, P., 2894 Fredericks, W.J., 2067 Freedman, L.P., 129 Friedman, J.R., 2067 Friedman, K.L., 1595 Friend, S., 2382 Friesen, J.D., 489 Fritz, A., 2759 Fuchs, E., 165 Gaal, T., 16 Gaget, R.F., 208 Gaiano, N., 3141 Galceran, J., 1382 Gallagher, P.A., 2167 Gallie, B.L., 3051 Gansmuller, A., 80 Garrett, K., 1173 Gaskins, C., 118 Gasser, S.M., 1796 Gaubatz, S., 447 Gauthier, Y., 1284 Gayko, U., 566 G6rard, M., 2326 Geiduschek, E.P., 725 Gibson, M., 1219 Gilson, E., 1297, 1796 Girard, L., 1930 Gish, B., 1773 Gisselbrecht, S., 3003 G6mez-Skarmeta, J.L., 2935 G6decke, S., 1184 Godley, L.A., 836 Gonzalez, F.J., 60 Goodrich, L.V., 301 Gordon, J.I., 985 Gotta, M., 1796 Gourse, R.L., 16 Gozani, O., 244 Graf, T., 2720 Grallert, B., 2644 Grandal, I., 2038 Gray, S., 700 Greco, T.L., 313 Green, M.R., 261, 517, 2368 Gribnau, J., 2894 Grisham, J., 245 Grondona, J.M., 80 Gronemeyer, H., 2326 Gross, C.A., 3170 Grosschedl, R., 1382 Grossman, A.D., 2014 Grosveld, F., 2894 Grosveld, G., 3156 Groudine, M., 185, 1979 Grumbling, G., 2302 Grunkemeyer, J.A., 2981 Grunstein, M., 686, 1327 Gruszynski-DeFeo, E., 672

Gu, C., 2222 Gu, L., 826 Gualdi, R., 1670 Guermah, M., 2389 Guidos, C., 2038 Guo, L., 165 Gutkind, J.S., 1455 Ha, I., 3041 Haag, T.A., 672 Hacohen, N., 2912 Hafen, E., 2759 Haga, T., 1736 Hagman, J., 2198 Hagstrom, K., 3202 Hamada, Y., 1670 Hamer, J.E., 2696 Hammerschmidt, M., 647,

2452 Han, J., 461 Han, Z., 2732 Hanahan, D., 2105 Hanna, Z., 1930 Hannon, G., 1633 Hansen, S.K., 2903 Hara, Y., 60 Harkness, T.A.A., 686 Harland, R.M., 1880 Harlow, E., 1621, 1633 Harper, J.W., 1491 Harris, A.W., 2055 Harris, C.C., 1219 Hartenstein, V., 672 Hartley, L., 70 Harvey, R.P., 70 Hateboer, G., 2969 Hatini, V., 1467 Hawley, R.S., 2383 Hayashi, S., 659 Hayday, A.C., 948 Haynes, M., 220 Hazel, T.G., 3129 He, T.-C., 1945 Heid, p.J., 1543 Heintz, N., 2389 Heitman, J., 279 Henderson, D.W., 1455 Hengge-Aronis, R., 1143 Henry, M., 1233 Hentsch, B., 70 Hermiston, M.L., 985 Herzlinger, D., 1467 Hill, R.E., 435 Hinman, A., 2971 Hogaard, A., 1162 Hodsdon, W., 2198 Hoeijmakers, J.H.J., 1219 Hoekstra, M.F., 2423 Hoemann, C., 1930 Hoffman, E.S., 948 Hoffmann, A., 2389 Hofmann, F., 851, 2949 Hogan, B.L.M., 1580, 1657 Holmes, S.G., 1021 Holtzman, D.A., 2423 Hopkins, N., 3141 Hopper, A.K., 1608


Hoppler, S., 2805 Horstmann, H., 2179 Horvitz, H.R., 578, 1073,

1289, 1953 Hou, D.-X., 528 Hsu, T., 1411 Hu, M.C.-T., 2251 Huang, E., 1433 Huang, M.T.F., 2038 Huang, X.-P., 2067 Huang, Y.-J., 351 Hudson, D.L., 1724 Huh, S.O., 1467 Hunter, W.J., 2981 Hwang, D.-Y., 338 Igel, H., 220 Imbalzano, A.N., 905, 1479 Ingham, P.W., 2003 Ingledue, T.C., III, 3028 Inostroza, J.A., 1049 Ip, Y.T., 2732 Irish, V.F., 1812 Isaac, D.D., 103 Ishii, S., 528 Ishov, A.M., 196 Izaurralde, E., 1683 Jacinto, A., 2003 Jacks, T., 1621, 1633, 2055 Jackson-Grusby, L., 1008 Jaenisch, R., 1008, 1991 Jallepalli, p.v., 541 Jan, L.Y., 421 Jan, Y.N., 421 Jarmolowski, A., 1683 Jayaraman, L., 2438 Jenni, M., 2759 Jensen, D.E., 2067 Jia, X., 16 Jiang, R., 3105 Jiang, Y.W., 604 Jiang, Z., 3051 Joazeiro, C.A.P., 725 Johe, K.K., 3129 Johnson, R.C., 2769 Johnson, R.L., 301 Jolicoeur, P., 1930 Jones, K.A., 37 Jones, N., 2289 Josso, N., 2577 Joyner, A.L., 3077 Juguilon, H., 196 Kablar, B., 1173 Kadonaga, J.T., 37, 711 Kadowaki, T., 3116 Kafatos, F.C., 1411 Kaiser, D., 740 Kalla, K.A., 1751 Kamimura, J., 2212 Kane, M.F., 407 KaneioIshii, C., 528 Kang, C.M., 2265 Karim, F.D., 272 Karlovich, C.A., 1194 Karrim, J., 2105 Kassavetis, G.A., 725 Kassis, J., 1108

Kastner, P., 80 Kataoka, Y., 659 Kauffmann, R.C., 2167 Kaufman, T.C., 176 Kaufmann, J., 873 Kawakami, K., 3141 Ke, N., 634 Keck, J.G., 37 Keegan, K.S., 2423 Kehrli, E., 2335 Kelly, T.J., 541 Kerkhoven, R.M., 2969 Kerr, K., 2600 Keys, D.A., 887, 2551 Kieser, A., 1455 Kim, J.B., 1096 Kim, J.M., 634 Kimelman, D., 1433 Kimsey, H., 740 Kimura, S., 60 Kingston, R.E., 905, 1479,

2782 Kinzler, K., 1945 Kirschner, M.W., 3081 Kiseleva, E., 2881 Kiyokawa, H., 3065 Klein, R., 2849 Klemm, J.D., 27 Klingensmith, J., 3116 Knauf, U., 2782 Knight, S.A.B., 1917 Knowles, G., 2038 Ko, L.J., 1054, 2438 Kobayashi, M., 1783 Koch, C., 129 Koff, A., 948, 3065 Kojima, T., 1645 Kolch, W., 1455 Kolodner, R., 407, 1433 Kondo, K., 1783 Kopp, J.B., 836 Kornak, J.M., 2981 Kornberg, R.D., 2131 Korsmeyer, S.J., 2859 Koshland, D., 3081 Kosman, D.J., 1917 Kowalczykowski, S.C., 1890 Kozak, C.A., 1930 Krall, L., 245 Krasnow, M., 2912 Kratochwil, K., 1382 Kraut, R., 659 Kremmer, E., 1455 Krezel, W., 80 Krishnan, V.V., 16 Kron, S.J., 2831 Kuempel, P., 1162 Kuo, A., 2117 Kwon, L.F., 1917 Kwon, Y.T., 816 Kyriakis, J., 2782 Labb6, S., 1917 Labosky, P.A., 1657 Lagrange, T., 2657 Lai, E., 1467 Laird, P.W., 1008

Lamonerie, T., 1284 Lanct6t, C., 1284 Landsman, D., 1049 Lane, E.B., 1724 Lawrence, P.A., 3183 Lazazzera, B.A., 2014 Lee, B.-S., 887 Lee, D., 2212 Lee, M.-H., 129, 1621, 1633 Lee, M.S., 1233 Lee, T., 2912 Lee, W.-H., 1835, 1870, 2794 Lehmann, R., 3077 Lei, H., 1008 Leid, M., 80 Leigh, I.M., 1724 Leng, X., 1491 Leu, T.M.J., 948 Levin, P.A., 478 Levine, A.J., 2971 Levine, M., 700, 3195 Levinson, R.S., 2131 Levitt, P., 1049 Lewis, J.D., 1683 Li, B., 1310 Li, E., 1008 Li, J., 2212 Li, R., 70 Li, S., 1835 Li, S., 2167 Li, X.-Y., 517 Liaw, L., 1657 Lilly, M.A., 2514 Lim, S.-K., 154 Lin, C.-S., 154 Ling, X., 686 Linke, S.P., 934 Lints, T.J., 70 Lioubin, M.N., 1084 Liu, C.-Y., 1835 Liu, M., 129 Liu, X.-D., 592 Liu, Y., 1395 Livingston, D.M., 851, 2478,

2949 Lobel, L., 2189 Losick, R., 478, 2348 Lou, H., 208 Louarn, J., 1152 Louarn, J.-M., 1152 Lowell, C.A., 1845 Lu, H.-C., 176 Lu, J., 2222 Lu, Q., 1327 Lundblad, V., 3094 Lupold, S.E., 1219 Lustig, A.J., 1310 Lutz, B., 176 Lutz, C.S., 325 Lynch, K.W., 2089 Lyons, I., 70 Ma, X.-J., 1327 Macdonald, P.M., 2600 Madden, K., 777 Magis, W., 185 Magnin, T., 794

Maillet, L., 1796 Maira, S.-M., 2198 Majerus, P.W., 1051 Maniar, H.S., 2222 Maniatis, T., 1356, 2089 Manley, J.L., 325, 862, 1569,

2588 Marcand, S., 1297, 1796 Marini, F., 395 Mark, M., 80 Markussen, F.-H., 2179 Marsischky, G.T., 407 Martel, L.S., 2491 Martelli, F., 2949 Marth, J.D., 3051 Martin, D.I.K., 185 Marzluff, W.F., 3028 Matsui, W., 1271 Mattaj, I.W., 1683 Matzuk, M.M., 2577 Maul, G.G., 196 McEachern, M.J., 1822 McGonigle, B., 1812 McGrath, J.A., 1724 McGuigan, C., 1683 McKay, R.D.G., 3129 McKnight, S.L., 367 McLean, W.H.I., 1724 McMahon, A.P., 313, 647,

2452 McMahon, J.A., 301,313 McMillan, J.R., 1724 Meehan, D.T., 2981 Megeney, L.A., 1173 Mellerick, D.M., 1108 Merli, C., 1260 Mermelstein, F., 1049 Meyer, C.F., 2251 Meyn, M.S., 2411, 2423 Michaud, N.R., 2684 Michelson, A.M., 3003 Milenkovic, L., 301 Millar, J.B.A., 2289 Miller, D., 176 Miller, J.R., 1433, 2527 Milliman, C.L., 2859 Minichiello, L., 2849 Minn, A.J., 2621 Mischak, H., 1455 Mishina, Y, 2577 Missero, C., 3065 Mitchell, P., 502 Miyake, T., 1783 Mlodzik, M., 50 Modha, D., 461 Modolell, J., 2935 Montell, D.J., 2912 Moon, R.T., 1433, 2527, 2805 Moose, S.P., 3018 Moretti, P., 1297 Morris, D.K., 3094 Morrison, D.K., 566, 2684 Moss, S.B., 2423 Mueller, J.E., 351, 2158 Muffler, A., 1143 Mukai, S., 1621

Mullen, J.R., 2222 Muller, M., 3202 Muller, T., 3129 Mulligan, G., 1621, 1633 Murayama, A., 1783 Murphy, M., 2971 Murthy, K.G.K., 325 Mushinski, J.F., 1455 Nacht, M., 2055 Nagappan, O., 1162 Naik, P., 2105 Nakanishi, M., 804 Nasmyth, K., 129, 1516 Navas, T., 2632 Neilson, E.G., 2067 Ness, S.A., 1858 Neville, M., 220 Nevins, J.R., 1422 Newhouse, M.W., 313 Newton, E.M., 2782 Nguyen, T.T., 887 Nickels, J.T., 382 Nielsen, M., 1162 Nikitin, A.Yu, 1870 Nikolic, M., 816 Nogi, Y., 887 Nomura, M., 887, 2551 Nordstrom, W., 1773 Norris, I.L., 862 Nuez, B., 2894 Nurse, P., 2644 Nyland, S.V.M., 1595 O'Connell, S., 1751 O'Connor, J.P., 325 Oda, H., 659 Odenwald, W.F., 1108 O'Farrell, P.H., 2505 Oft, M., 2462 Ohno, M., 997 Olde, B., 1108 Oldread, E., 2478 Oliner, J.D., 2903 Omatyar, L., 672 Oren, M., 826 Orphanides, G., 2657 Orrico, F.C., 1858 Owaribe, K., 1724 Owen, M.J., 948 Owens, J., 836 Pabo, C.O., 27 Paglino, J.J., 836 Panning, B., 1991 Parker, M.M., 351 Parker, S.B., 1491 Passoni, L., 948 Patra, D., 1503 Patte, J., 1152 paull, T.T., 2769 Pazin, M.J., 37 Peli, J., 2462 Perez, D., 461 Perkins, L.A., 566 Perrimon, N., 566, 3116 Peters, J.-M., 3081 Petfalski, E., 502 Philipova, D., 2222

Philipsen, S., 2894 Phillips, R.A., 3051 Piatti, S., 1516 Pineau, T., 60 Plasterk, R.H.A., 755 Plug, A.W., 2423 Polyak, K., 1945 Powell, F.L., 1751 Price, C.W., 2265 Pritchard, D.K., 1131 Prives, C., 1054, 2438 Prusiner, S.B., 1736 Ptashne, M., 2359 Pulkkinen, L., 1724 Qiu, W.R., 2251 Quinn, J.C., 435 Ramos, Y.F.M., 816 Ramqvist, T., 2720 Rao, L., 461 Rauscher, F.J., iii, 2067 Ray, R.P., 1711 Reed, R., 244 Reese, J.C., 2368 Reichmann, E., 2462 Reinberg, D., 1049, 2657 Rey, R., 2577 Riesgo-Escovar, J.R., 2759 Riethmacher, D., 1184 Riley, D.J., 2794 Rio, D.C., 921 Roberts, J.M., 1979 Roeder, R.G., 2389 Roemer, T., 777 Rohrschneider, L.R., 1084 Romo, A., 196 Rosbash, M., 1699 Rosenfeld, M.G., 1751 Ross, W., 16 Roth, D.B., 553 Roth, S.Y., 1247 Rothman, J.H., 1543 Rouvi6re, P., 3170 Rubin, G.M., 272, 2684 Rudaz, C., 2462 Rudnicki, M.A., 1173 Rugg, E.L., 1724 Rusconi, C.P., 2870 Russell, P., 2276 Ruvkun, G., 1395, 3041 Saavedra, C., 1608 Sabbatini, P., 461 Sadoff, B.U., 2564 Sager, B.M., 2237 Saigo, K., 1645 Samuels, M., 2289 Samuelson, G.C., 2981 Sanchez, Y., 2632 Sawa, H., 2189 Sayers, R., 2981 Scalzo, D., 185 Schatz, D.G., 948 Schedl, P., 3202 Schek, N., 325 Scherer, S.S., 1751 Schier, A.F., 3077 Schleiffer, A., 129


Schlissel, M., 2055 Schneider, R.J., 1557 Schnepp, B., 2302 Schiipbach, T., 1711 Schubiger, G., 1131 Schultz, M.C., 686 Schwarz, H., 2462 Scott, M.P., 301 Segall, J.E., 118 Segil, N., 2389 Seicher, D.W., 2067 Seitz, T., 1455 Serbedzija, G.N., 2452 Shaham, S., 578, 1073 Shao, J., 873 Shapiro, L., 1532 Sharp, P.A., 2079 Sheaff, R.J., 1979 Sheridan, P.L., 37 Sherratt, D., 762 Shieh, J.-C., 2289 Shilo, B.-Z., 93, 2993 Shimura, Y., 997 Shiozaki, K., 2276 Shore, D., 1297 Shvarts, A., 2969 Silver, P.A., 1233 Simanis, V., 2707 Simard, C., 1930 Simcox, A., 2302 Simkovich, N., 2359 Singh, H., 2335 Sisco, P.H., 3018 Skeath, J.B., 3003 Slack, F.J., 740 Sluss, H.K., 2732 Smale, S.T., 873 Smibert, C.A., 2600 Smith, D., 2158 Smith, F.J.D., 1724 Smith, J.R., 804 Smith, M.M., 1247 Snyder, M., 777 Sogaard-Andersen, L., 740 Soares, V.C., 1467 Sohrmann, M., 2707 Solomon, J.M., 2014 Solomon, N.M., 272 Sonnenberg-Riethmacher, E.,

1184 Soriano, P., 1845 Spence, A.M., 2314 Spiegelman, B.M., 974, 1096 Spradling, A.C., 2514 St-Arnaud, R., 1763 Starr, D.B., 1271 Steffan, J.S., 2551 Stepanova, L., 1491 Stephens, C., 1532 Stern, D.F., 395 Stillman, D.J., 604 Storb, U., 2335 Strasser, A., 2055 Stutz, F., 1699 Sun, X., 2881 Sun, Z., 395

Sutherland, J.D., 1411 Suzuki, T., 1783 Symington, L.S., 2025 Symonds, H., 826 Szymanski, P., 3195 Tacke, R., 1569 Takada, S., 313 Takagaki, Y., 2588 Takahashi, F., 1645 Takahashi, T., 528 Takahisa, M., 1783 Takeda, T., 2289 Takeichi, M., 659 Talbot, W.S., 3077 Tan, T.-H., 2251 Tanaka, Y., 528 Tang, H., 16 Taylor, D., 2732 Taylor, E.M., 2423 Tecklenburg, M., 1162 Telling, G.C., 1736 Tempst, P., 1049 Tepass, U., 672 Therrien, M., 272, 1284, 2684 Thiele, D.J., 592, 1917 Thomas, J.R., 1271 Thompson, C.B., 2621 Thorner, J., 2831 Thress, K., 1979 Timchenko, N.A., 804 Tjian, R., 50, 2903 T6r6k, T., 672 Toda, T., 2289 Togashi, S., 1783 Tollervey, D., 502 Tontonoz, P., 974 Toone, W.M., 2289 Torchia, M., 1736 Torres, M., 1443 Tracy, R.B., 1890 Tremblay, J.J., 1284 Tremblay, P., 1736 Trimborn, T., 2894 Tsai, L.-H., 816 Tsai, S., 1084 Tsou, A., 934 Tucker, K.L., 1008 Tung, K.-S., 1608 Ueda, R., 1783 Uemura, T., 659 Uitto, J., 1724 van der Spoel, A., 3156 Van Dyke, T., 245, 826 Varmus, H.E., 836 Vermeulen, W., 1219 Verrijzer, C.P., 873 Vidal, M., 1206 Vincent, J.-p., 3183 Virbasius, C.-M.A., 2368 Virta-Pearlman, V., 3094 Visa, N., 2881 Vogelstein, B., 1945 Volk, T., 2993 Vos, J.C., 755 Voytas, D.F., 634 Vu, L., 887

Wade, M., 245 Wahl, G.M., 934 Waldman, T., 1945 Walter, B., 1184 Walters, M.C., 185 Wang, J., 220 Wang, l., 2588 Wang, K., 2859 Wang, W., 2117 Wang, X., 2251 Wang, X.W., 1219 Wang, Z., 2949 Wang, Z-F., 3028 Ward, J.M., 60 Wassarman, D.A., 272 Wasylyk, B., 2198 Weinberg, R.A., 1633 Weitzman, M.D., 196 Weizman, I., 93 Wells, S.E., 220 West, J.D., 435 Weston, K., 2732 Wharton, R.P., 1422, 2610 Wheat, W., 2198 White, E., 1,461 Whitfield, M.L., 3028 Wightman, B., 3041 Wijgerde, M., 2894 Wilde, M., 804 Wilder, E., 3116 Wilk, R., 93 Wilkinson, M.G., 2289 Williams, B.O., 1621 Williams, C.J., 2038 Wilson, J.E., 2600 Wolkow, C.A., 2145 Wong, M.H., 985 Wright, R., 1532 Wu, H., 245 Wu, Y., 2359 Wurtz, T., 2881 Xie, J.-E., 1206 Xiong, Y., 245 Xu, G., 1219 Xu, J.-R., 2696 Xu, Y., 2401, 2411 Xue, D., 1073 Xue, Y., 2117 Yamamoto, K.R., 1271, 2131 Yang, X., 2265 Yao, T.-P., 2478 Yasukawa, T., 528 Yeh, H., 1219 Yeung, K., 1049 Yin, C., 826 Yin, X.-M., 2859 Yokomori, K., 50 Yost, C., 1443 Yotov, W.V., 1763 Younger-Shepherd, S., 421 Yudkin, M.D., 794 Yueh, A., 1557 Zakany, J., 2326 Zachary, K., 3116 Zacksenhaus, E., 3051 Zaret, K.S., 1670

Zeidler, M.P., 50 Zeng, Y., 1835 Zhang, J., 2167 Zhang, S.-D., 1108 Zhao, G.-Q., 1657 Zheng, M., 1670 Zhou, J., 3195 Zhou, S., 2117, 2903 Zhu, C., 553 Zou, S., 634 Zuo, P., 1356 Zweiger, G., 1532

3226 GENES & D E V E L O P M E N T

Subject Index, Volume 10 (1996)

ACT3 gene, epigenetic effects on yeast transcription caused by mutations (Jiang and Stillman), 604- 619

Actin, LIM-mediated binding of MLP to cytoskeleton (Arber and Ca- roni), 289-300

Actin-related protein, epigenetic effects on yeast transcription caused by mutations (Jiang and Stillman), 604-619

Activating transcription factor-2 Spcl regulation of S. pombe homolog

Atfl (Shiozaki and Russell), 2276-2288

role of DNA-binding domain as inhib- itory region (Li and Green), 517- 527

Activation, transcriptional by aCTD-DNA interactions in E. coli

(Gaal et al.), 16-26 CBP as a coactivator of c-Myb (Dai et

al.), 528-540 cell-cycle regulation of SBF binding

(Koch et al.), 129-141 during Drosophila embryogenesis

(Pritchard and Schubiger), 1 1 3 1 - 1 1 4 2

functional TBP epitopes for Pol II activity (Bryant et al.), 2491-2504

inhibition by the ATF-2 DNA-binding domain (Li and Green), 517-527

regulation of transcriptional pausing on nucleosomal templates (Brown et al.), 1479-1490

role of TFIIA-TFIID complex formation in gene activation (Chi and Carey), 2540-2550

specificity of Myc (Desbarats et al.), 447-460

Activators, gene-specific, findings presented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary

Activin, participation of Madr2 in signaling pathway (Baker and Har- land), 1880-1889

Activity, context-dependent, altered intracellular receptor activation (Start et al.), 1271-1283

ADD1, role in adipocyte differentiation (Kim and Spiegelman), 1096- 1107

Adenine DNA methyltransferases, CcrM as target of Lon protease in C. crescentus (Wright et al.), 1532-1542

Adenovirus POD organization and viral DNA rep-

lication (Doucas et al.}, 196- 207

regulation of E2F degradation by trans-

forming proteins (Hateboer et al.), 2960-2970

use of ribosome jumping for translation of late mRNAs (Yueh and Schneider), 1557-1567

Adhesion proteins, role of plx in tracheal function (Zhang et al.), 1108- 1119

Adipogenesis. See also Differentiation, adipocyte

differential activity of multiple PPAR isoforms (Brun et al.), 974-984

role of Rb interaction with C/EBPs in adipocyte terminal differentiation lChen et al.), 2794-2804

Adipose tissue, differential adipogenic activity of multiple PPAR isoforms (Bran et al.), 974-984

AINTEGUMENTA, similarity of maize Gtossyt5 tMoose and Siscol, 3018-3027

Alport syndrome, COL4A3-deficient mice as model (Cosgrove et al.), 2981- 2992

AML1, homologous domains found in Drosophila Lozenge (Daga et al.), 1194-1205

Anaphase, regulation in S. cerevisiae by APC-dependent degradation of Pdslp (Cohen-Fix et al.), 3081- 3093

Anaphase-promoting complex, role in Pdslp degradation in (Cohen- Fix et al.), 3081-3093

Anchoring site, binding by U2 snRNP proteins (Gozani et al.), 233-243

Anti-cancer agents, p53-dependent cell cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947

Anticodon, as signal sequence for tRNA import into mitochondria (Rusconi and Cech), 2870-2880

Antimetabolites, induction of p53-dependent cell-cycle arrest by ribonucleotide depletion [Linke et al.), 934-947

Antisigma factor, interaction of SpoIIAB with ~r in B. subtilis (Decatur and Losick), 2348-2358

APC. See Anaphase-promoting complex APETALA2, similarity of maize Glossyl 5

(Moose and Sisco), 3018-3027 APETALA3, nuclear colocalization with

PISTILLATA (McGonigle et al.), 1812-1821

Apoptosis. See also Programmed cell death

Bcl-xL and p53 in mitotic checkpoint control (Minn et al.), 2621-2631

BID as novel death agonist possessing only a BH3 domain (Wang et al.), 2859-2869

effects of wild-type p53 transgene ex-

pression (Godley et al.), 836- 850

functional interaction of E1B 19K with Bax (Han et al.), 461-477

genetic determinants of p53 induction (Polyak et al.), 1945-1952; Erra- tum, 2818

induction by ectopic E2F expression in Drosophila (Asano et al.1, 1422- 1432

negative regulation of MAP4 expression by p53 (Murphy et al.), 2971-2980

opposing cell-death activities in C. elegans neurons (Shaham and Horvitz), 578-591

p53 levels and extent of tumor cell response (Chen et al.), 2438-2451

in plO7-null mice (Lee et al.), 1621- 1632

in R b ' / mice (Nikitin and Lee), 1870-1879

regulation of skeletal muscle cell proliferation by Rb (Zackenhaus et al.), 3051-3064

regulators and pathways (White), 1-15 Review

rise and fall during multistage tumorigenesis (Naik et al.), 2105-2116

role of grim in Drosophila (Chen et al.),

1773-1782 p53 (Ko and Prives), 1054-1072 Re-

view TrkB and TrkC in promoting neuron

survival (Minichello and Klein), 2849-2858

XPB and XPD in p53-dependent pathway (Wang et al.), 1219- 1232

substrate specificities of CED-3/ICE- like proteases (Xue et al.), 1073- 1083

suppression by E26 v-Myb (Frampton et al.), 2720-2731

tissue-specific inactivation of p53 tumor suppression in mice (Bow- man et al.), 826-835

up-regulation by dominant interfering Myb (Taylor et al.), 2732-2744

Appressorium, formation during rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706

Arabidopsis, nuclear colocalization of APETALA3 and PISTILLATA (McGonigle et al.), 1812-1821

araucan, positive regulation of by Dpp and Ci during wing patterning (G6mez-Skarmeta and Mod- olell), 2935-2945

Arches, branchial, role of pescadillo development in zebrafish (Allende et al.), 3141-3155

ASF. See ASF/SF2


ASF/SF2, role in activation of polyadenylation by in-

tron enhancer (Lou et al.), 208- 219

cell viability (Wang et al.), 2588-2599 in splicing (Manley and Tacke), 1569-

1579 Review Asymmetric cell division. See Cell divi-

sion, asymmetric Asymmetry, coupling of cell lineage

asymmetry with transcription of unc-86 (Baumeister et al.), 1395-1410

Ataxia telangiectasia. See ATM Atf-1, regulation by Spcl in S. pombe

(Shiozaki and Russell), 2276-- 2288

ATF2. See Activating transcription factor-2

ATM association with meiotically pairing

chromosomes (Keegan et al.), 2423-2437

effects of gene inactivation in mice (Xu et al.), 2411-2422

role in cell-cycle regulation (Xu and Balti-

more), 2401-2410 different cell types and functional

links to p53 (Hawley and Friend), 2383-2388 Review

Atr, association with meiotically pairing chromosomes (Keegan et al.), 2423-2437

Attenuator, Fab-7 as boundary element in Drosophila

(Zhou et al.), 3195-3201 as chromatin domain boundary in

Drosophila (Hagstrom et al.), 3202-3215

Axial growth, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777-793

Axis formation, role of ~-catenin and Xgsk-3 in Xenopus (Yost et al.), 1443-1454

AXL2, role in axial growth site selection in yeast (Roemer et al.), 777- 793

B

B cells Pax-5 recruitment of Ets proteins to

mb-I promoter (Fitzsimmons et al.), 2198-2211

proteins, sequence-specific DNA binding of POU domain coactivator OCA-B (Cepek et al.), 2079- 2088

role of p3OO/CBP and bHLH proteins in differentiation (Eckner et al.), 2478-2490

Bacillus subtilis

bifunctionality of SpoIIE in asymmetric cell division and cell-specific transcription (Feucht et al.), 794-803

bipolar localization of FtsZ (Levin and Losick), 478-488

interaction of SpoIIAB with (r F (Deca- tur and Losick), 2348-2358

role of extracellular peptide in different development pathways (So- lomon et al.), 2014-2024

signaling by serine kinases and phosphatases in response to stress (Yang et al.), 2265-2275

BAFs. See BRGl-associated factors bagpipe, role in segmentation and speci-

fication of Drosophila mesoderm (Azpiazu et al.), 3183- 3194

Bar, positive regulation by Drosophila Lozenge (Daga et al.), 1194- 1205

Base pairing, of U2 and U6 snRNAs during splicing (Field and Friesen), 489-501

Basement membrane, effects of collagen COL4A3 gene inactivation in mice (Cosgrove et al.), 2981- 2992

basket, as encoding Drosophila JNK (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759- 2768

Bax interaction with E1B 19K (Han et al.),

461-477 up-regulation by p53 (Ko and Prives),

1054-1072 Review Bcl-2 family


role in apoptosis (White), 1-15 Review cell-death activities in developing C.

elegans neurons (Shaham and Horvitz), 578-591

Bcl-x L BID as novel death agonist possessing

only a BH3 domain (Wang et al.), 2859-2869

regulation of apoptosis during multistage tumori-

genesis (Naik et al.), 2105-2116 bcl-2 by dominant interfering Myb

(Taylor et al.), 2732-2744 role in mitotic checkpoint control

(Minn et al.), 2621-2631 up-regulation of bcl-2 by E26 v-Myb

(Frampton et al.), 2720-2731 Belousov-Zhabotinsky reaction, propa-

gation of traveling waves (Sager), 2237-2250 Review

B-Catenin perturbation of distribution by forced

expression of E-cadherin (Her- miston et al.), 985-996

regulation by Xgsk-3 (Yost et al.), 1443-1454

role in signal transduction during embryogenesis (Miller and Moon), 2527-2539 Review

~-Globin, role of EKLF in human gene competition (Wijgerde et al.), 2894-2902

~-Globin 5'HS2 enhancer, in the study of position-effect variegation (Wai- ters et al.), 185-195

BH3 domain, in novel death agonist BID (Wang et al.), 2859-2869

bHLH proteins. See Helix-loop-helix proteins, basic

bicoid, novel related homeo box factor Ptxl (Lamonerie et al.}, 1284- 1295

BID, novel death agonist possessing only a BH3 domain {Wang et al.), 2859-2869

Bithorax complex, Fab-7 attenuation of enhancer-promoter in-

teractions in Drosophila (Zhou et al.), 3195-3201

chromatin domain boundary in Droso- phila (Hagstrom et al.), 3202- 3215

BMP-4, activation of Lefl expression (Kratochwil et al.), 1382-1394

Bmp4, regulation by zebrafish dino and swirl (Hammerschmidt et al.), 2452-2461

BMPs. See Bone morphogenetic proteins Bone morphogenetic proteins

regulation of Bmp4 by dino and swir/ in zebrafish (Hammerschmidt et al.), 2452-2461

role in embryonic development (Hogan), 1580-1594 Review

role of Bmp8b in spermatogenesis and fertility in mice (Zhao et al.), 1657-1669

Boundary elements, Fab-7 attenuation of enhancer-promoter in-



Branchial arches. See Arches, branchial Branchpoint sequences, binding up-

stream by U2 snRNP proteins and spliceosome assembly (Goz- ani et al.), 233-243

Brcal, effects of gene inactivation in mice (Liu et al.), 1835-1843

Breathless, role in patterning cell migration and branching in Droso- phila (Lee et al.), 2912-2921

BRGl-associated factors, similarity to yeast SWI/SNF factors (Wang et al.), 2117-2130

BSAP, recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211


B u d site inhibition of ATF-2 activation by its

DNA-binding domain (Li and Green), 517-527

role of Axl2p in selection (Roemer et al.), 777-793

bZIP protein. See Leucine zipper protein, basic

C

C-factor. See C-signaling C-signaling

branched pathway in Myxococcus (Sogaard-Andersen et al.), 740- 754

traveling wave propagation in Myxo- coccus morphogenesis tSager}, 2237-2250 Review

c-Jun amino-terminal kinases activation by HPK1 (Hu et al.), 2251-

2264 Drosophila pathway mediating mor-

phogenesis and an immune response (Sluss et al.), 2745-2758

regulation of Atfl by Styl in S. pombe (Wilkinson et al.), 2289-2301

c-Myb, role of EVES motif in regulation (Dash et al.), 1858-1869

c-myc collaboration with NotchI for onco-

genesis (Girard et al.), 1930- 1944

specificity in gene activation by Myc (Desbarats et al.), 447-460

c-ros, role of in epithelial development (Sonnenberg-Riethmacher et al.), 1184-1193

c - s r c

effects of gene disruptions in mice (Lowell and Soriano), 1845- 1857 Review

regulation of eye development by related Drosophila gene Dsrc41 (Takahashi et al.), 1645-1656

C/EBPs. See CCAAT/enhancer-binding proteins

Cadherins colocalization of Drosophila Dsrc41

and DE-cadherin in developing eyes (Takahashi et al.), 1645- 1656

role in intestinal epithelial cell migration (Hermiston et al.), 985-996

Caenorhabditis elegans coupling of cell lineage asymmetry

with unc-86 transcription (Bau- meister et al.), 1395-1410

in vitro transposition of Tcl (Vos et al.), 755-761

opposing cell-death activities in developing neurons (Shaham and Horvitz), 578-591

posterior patterning by vab-7 (Ahr- inger), 1120-1130

role of FEM-2 in sex determination (Chin-

Sang and Spence), 2314-2325 lin-14 3' UTR in down-regulation of

translation (Ha et al.), 3041- 3050

lin-17 in asymmetric cell division in (Sawa et al.), 2189-2197

sere-4 in neuronal and mesodermal development (Basson and Hor- vitz), 1953-1965

SL1 trans-spliced leader RNA in embryogenesis (Ferguson et al.), 1543-1556


Calcitonin alternative splicing of pre-mRNA (Lou

et al.), 208-219 gene-related peptide, generation

through alternative splicing of calcitonin pre-mRNA (Lou et al.), 208-219

cAMP. See Cyclic AMP Cancer. See also Carcinogenesis; Onco-

genesis; Specific oncogenes; Tu- morigenesis

ATM as susceptibility gene (Hawley and Friend), 2383-2388 Re- view

breast, effects of Brcal gene inactivation in mice (Liu et al.), 1835- 1843

p53-dependent cell cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947

rearrangement of Notch l in mouse thymomas in MMTV/myc transgenic mice (Girard et al.), 1930-1944

redundancy of MSH3 and MSH6 in MSH2-dependent mismatch repair (Marsischky et al.), 407- 420


Cap-binding complex, nuclear Mudl3p as yeast homolog of CBP20

(Colot et al.), 1699-1708 role in pre-mRNA recognition and

splicing (Lewis et al.), 1683- 1698

Cap-binding protein, requirement for ribosome jumping in virus-infected and heat-shocked cells (Yueh and Schneider), 1557- 1567

Cap-prevented recombination. See Re- combination, cap-prevented

Carboxy-terminal domain, role in Pol II transcription (Orphanides et al.), 2657-2683 Review

Carcinogenesis, neuroendocrine role of Rb (Nikitin and Lee), 1870-1879

Caulobacter crescentus, role of Lon protease in cell-cycle control of DNA methylation (Wright et al.), 1532-1542

caupolican, positive regulation of by Dpp and Ci during wing patterning (G6mez-Skarmeta and Modolell), 2935-2945

CBC. See Cap-binding complex, nuclear CBP. See CREB-binding protein CBP20, identification of yeast homolog

Mudl3p (Color et al.), 1699- 1708

CCAAT/enhancer-binding proteins, role of

C/EBP-~ in elevation of p21 (Tim- chenko et al.), 804-815

interaction with Rb in adipocyte terminal differentiation (Chen et al.), 2794-2804

CcrM, as target of Lon protease in Cau- lobacter (Wright et al.), 1532- 1542

CD40, role of TANK in CD40L-mediated NF-KB activation (Cheng and Baltimore), 963-973

Cdc2 kinase, inhibition by Ruml (Jalle- palli and Kelly), 541-552

Cdc2/cyclin B complexes, regulation by Xenopus Sucl homolog Xe-p9 (Patra and Dunphy), 1503-151

Cdc6, role in promoting replication during the cell

cylce (Piatti et al), 1516--1531 regulation of eukaryotic DNA replica-

tion (Diffley), 2819-2830 Review Cdc7, role in regulation of eukaryotic

DNA replication (Diffley), 2819-2830 Review

Cdcl0, AXL2 as high copy suppressor in spa2~ cdcl0-10 mutant strains (Roemer et al.), 777-793

Cdc 18, interaction with Rum 1 (Jallepalli and Kelly), 541-552

Cdc25, degradation of maternal mRNAs in maternal/zygotic transition (Edgar and Datar), 1966-1977

Cdc28p, role in regulation of eukaryotic DNA replication (Diffley), 2819-2830 Review

CDC37, encoding of protein kinase-targeting subunit of Hsp90 by mammalian homolog (Stepa- nova et al.), 1491-1502

CDC55, as encoding the regulatory subunit of ceramide-activated protein phosphatase in S. cerevisiae (Nickels and Broach), 382- 394

CDK inhibitors. See Cyclin-dependent kinase inhibitors

cdk2 regulation of cyclin E turnover by the

ubiquitin pathway (Clurman et al.), 1979-1990

role in control of pRB and E2F function


during G 1 exit (Hofmann and Livingston), 851-861

cdk3, dominant-negative inhibition of E2F-1 in Rb-independent man- ner (Hofmann and Livingston), 851-861

cdk5, regulation of neurite outgrowth (Nikolic et al.), 816-825

CDKs. See Cyclin-dependent kinases CED-3, substrate specificities of ICE-like

proteases (Xue et al.), 1073-1083 ced-3, role in cell-death activities in de-

veloping C. elegans neurons (Shaham and Horvitz), 578-591

ced-4, role in cell-death activities in developing C. elegans neurons (Shaham and Horvitz), 578-591

ced-9, role in cell-death activities in developing C. elegans neurons (Shaham and Horvitz), 578-591

Cell adhesion, role of cadherins in intesti-

nal epithelium (Hermiston et al.), 985-996

cycle arrest from p21 overexpression in

transgenic mice (Wu et al.), 245-260

arrest induced by ribonucleotide depletion (Linke et al.), 934-947

Bcl-x L and p53 in mitotic checkpoint control {Minn et al.), 2621-2631

cdk-dependent cyclin E ubiquitination (Clurman et al.), 1979- 1990

cdk2 and cdk3 action in G 1 (Hof- mann and Livingston), 851-861

ceramide-activated protein phosphatase mediates ceramide-induced G 1 arrest in Saccharomy- ces cerevisiae (Nickels and Broach), 382-394

coincident regulation with clonality during T-cell receptor development (Hoffman et al.), 948-962

cyclin E requirement for E2F-induced S phase (Duronio et al.), 2505-2513

determinants of late origin activation in yeast (Friedman et al.), 1595-1607

induction of S phase by ectopic E2F expression in Drosophila {Asano et al.), 1422-1432

influence of p53 levels on arrest (Chen et al.), 2438-2451

modulators of histone function in yeast (Ma et al.), 1327-1340

p53-dependent arrest induced by ribonucleotide depletion (Linke et al.), 934-947

parallel sensory branches for DNA damage signaling in S. cerevisiae (Navas et al.), 2632-2643

protection of E2F-1 from ubiquitin-

proteasome degradation pathway by Rb {Hofmann et al.), 2949-2959

regulation by ATM (Xu and Baltimore),

2401-2410 of E2F degradation by Rb family

proteins and adenovirus transforming proteins (Hateboer et al.), 2960-2970

of S-phase onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654

of SBF binding (Koch et al.), 129- 141

of skeletal muscle cell proliferation by Rb (Zackenhaus et al.), 3051-3064

by Xenopus Sucl homolog Xe-p9 {Patra and Dunphy), 1503-151

requirement for yeast TAFn90 (Apone et al.), 2368-2380

role of Lon protease in control of DNA

methylation (Wright et al.), 1532-1542

p21 in keratinocyte growth and differentiation {Missero et al.), 3065-3075

p53 (Ko and Prives), 1054-1072 Review

rapamycin-sensitive TOR function in yeast (Alarcon et al.), 279-288

Rb interaction with C/EBPs in adipocyte terminal differentiation (Chen et al.), 2794-2804

Rum 1 inhibition of Cdc2 kinase and interaction with Cdcl8 {Jalle- palli and Kelly), 541-552

termination of early program in Drosophila embryogenesis (Ed- gar and Datar), 1966-1977

timing of replication promotion by Cdc6 {Piatti et al.), 1516-1531

truncation of S phase during the Drosophila endocycle (Lilly and Spradling), 2514-2526

division asymmetric

coupling of cell lineage asymmetry with unc-86 transcription (Baumeister et al.), 1395-1410

role of lin-I 7 in C. elegans (Sawa et al.), 2189-2197

role of SpoIIE in Bacillus subtilis (Feucht et al.), 794-803

bipolar localization of FtsZ in Bacil- lus subtilis (Levin and Losick), 478-488

fate cadherins role in intestinal epitheli-

al cell migration (Hermiston et al.), 985-996

signal transduction role through ~-catenin during embryogenesis

(Miller and Moon), 2527-2539 Review

growth defects in ATM-deficient mice (Xu

et al.), 2411-2422 interactions, regulation by Dsrc41

in developing Drosophila eyes (Takahashi et al.), 1645-1656

invasion, regulation of tumor cell plasticity by TGF-[3 and Ha-Ras (Oft et al.), 2462-2477

regulation by ATM (Xu and Balti- more), 2401-2410

migration Breathless role in the Drosophila

tracheal system (Lee et al.), 2912-2921

C-signaling role and traveling wave propagation in Myxococcus (Sager), 2237-2250 Review

cadherins role in intestinal epithelium (Hermiston et al.), 985-996

cAMP role and traveling wave propagation in Dictyostelium (Sager), 2237-2250 Review

Heartless role in Drosophila development (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017

polarity, regulation by lin-I 7 in C. elegans (Sawa et al.), 2189-2197

rearrangement, epithelial E-cadherin role in Drosophila (Ue-

mura et al.), 659-671; (Tepass et al.), 672-685

signaling during Drosophila oogenesis (Ray

and Schfipbach), 1711-1723 Re- view

in hepatic specification of gut endoderm (Gualdi et al.), 1670-1682

role of extracellular peptide in different development pathways in B. subtilis (Solomon et al.), 2014- 2024

specificity conversion of ~NAC to myotube-

specific factor (Yotov and St-Ar- naud), 1763-1772

Pax-5 recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211

role of novel bicoid-related homeo box factor Ptxl (Lamonerie et al.), 1284-1295

sequence-specific DNA binding of B-cell POU domain coactivator OCA-B {Cepek et al.), 2079- 2088

tissue-specific inactivation of p53 tumor suppression in mice (Bow- man et al.), 826--835

Central nervous system. See Nervous system, central

Ceramide-activated protein phos-


phatase. See Protein phosphatase, ceramide-activated

Cerebellum, role of TrkB and TrkC in promoting granule neuron survival (Minichello and Klein), 2849-2858

CF. See Core factor CF2, role in EGF-R-activated dorsoven-

tral patterning (Hsu et al.), 1411-1421

Chaperone proteins, p50 Cdc37 as protein kinase-targeting subunit of Hsp90 (Stepanova et al.), 1491- 1502

Checkpoints activation by V(D)] recombination in

scid mice (Guidos et al.), 2038- 2054

Bcl-x L and p53 in control (Minn et al.), 2621-2631

cooperativity of p53 and SCID genes in tumorigenesis (Nacht et al.), 2055-2066

cyclin E role in truncation of S phase during the Drosophila endocycle (Lilly and Spradling), 2514- 2526


regulation of S-phase onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654

Spk1/Rad53 regulation by Mecl-dependent protein phosphorylation (Sun et al.), 395-406

topoisomerases role in chromosome condensation in S. cerevisiae (Castaflo et al.), 2564-2576

• preferred selection by RecA protein (Tracy and Kowalczykowski), 1890-1903

Cholesterol metabolism, mediation of SREBP transcriptional activity by CBP (Oliner et al.), 2903- 2911

Chromatin activator-dependent regulation of tran-

scriptional pausing on nucleosomal templates (Brown et al.), 1479-1490

findings presented at Cold Spring Har- bor meeting (McKnight), 367- 381 Meeting commentary

function of Swp73 in yeast Swi/Snf complex (Cairns et al.), 2131- 2144

identification of mammalian SWI/ SNF complexes (Wang et al.), 2117-2130

in transcriptional activation and repression (Kingston et al.), 905- 920 Review

interaction of Tupl with histones H3 and H4 (Edmondson et al.), 1247-1259

NF-KB p50 role in nucleosome arrange- ment of HIV-1 enhancer (Pazin et al.), 37-49

role in hepatic specification of gut endoderm (Gualdi et al.), 1670- 1682

silent, preferential integration of Ty5 (Zou et al.), 634-645

Chromosome association of Atr and Atm with mei-

otic pairs (Keegan et al.), 2423- 2437

condensation, role of topoisomerases in S. cerevisiae (Castafio et al.), 2564-2576

fragmentation in ATM-def icient mice (Xu et al.), 2411-2422

localization of TFIID and inhibition of activator-dependent transcription (Segil et al.), 2389-2400

organization dif resolvase site insertions in E. coli

(Kuempcl et al.), 1162-1171; Corrigendum, 1709

restriction of dif site activity in E. coli (Cornet et al.), 1152-1161

walk, to identify determinants con- trolling activation of yeast replication origins (Friedman et al.), 1595-1607

ci. See cubitus interruptus CIF, role in TFIID-dependent initiator

function (Kaufmann et al.), 873- 886

CIP- 1. See p21 CKIs. See Cyclin-dependent kinase in-

hibitors Clb5. See Cyclins Clb6. See Cyclins Cleavage-polyadenylation specificity

factor, interaction with U1 snRNP (Lutz et al.), 325-337

Clnl. See Cyclins Cln2. See Cyclins Cln3. See Cyclins CNS. See Nervous system, central Coactivators, transcriptional


interaction of CBP with (Dai et al.), 528-540

mediation of SREBP transcriptional activity by CBP (Oliner et al.), 2903-2911

role of TFIIA in Ras-mediated photoreceptor determination (Zeidler et al.), 50-59

sequence-specific DNA binding of B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2088

Coconversion, biases accompanying intron homing (Mueller et al.), 2158-2166

Cofactors

role of EVES motif in c-Myb regulation (Dash et al.), 1858-1869

transcriptional findings presented at Cold Spring

Harbor meeting (McKnight), 367-381 Meeting commentary

role of CIF in TFIID-dependent initiator function (Kaufmann et al.), 873-886

COL4A3, effects of gene inactivation in mice (Cosgrove et al.), 2981-2992

Collagen, effects of COL4A3 gene inactivation in mice (Cosgrove et al.), 2981-2992

Competence and sporulation stimulating factor, role of extracellular peptide in different development pathways in B. subtil is (Solomon et al.), 2014-2024

Competence, genetic, role of extracellular peptide in B. subtiIis (So- lomon et al.), 2014-2024

Conjugation Atfl regulation by

Spcl in S. pombe (Shiozaki and Rus- sell), 2276--2288

Styl in S. p o m b e (Wilkinson et al.), 2289-2301

conjugating plasmids as preferred targets for Tn7 (Wolkow et al.), 2145-2157

Copper transport, role of yeast protein Ctr3 (Knight et al.), 1917-1929

Core factor, requirement for TBP in UAF-dependent recruitment (Steffan et al.), 2551-2563

Corepressors, role of KAP-1 for KRAB domain (Friedman et al.), 2067- 2078

Corkscrew, analysis of interaction with Torso (Cleghon et al.), 566--577

Corrigenda Gertler et al., 2234 Kuempel et al., 1709

CPP32, similarity CED-3 substrate specificity (Xue et al.), 1073-1083

CPR. See Recombination, cap-prevented CPSF. See Cleavage-polyadenylation

specificity factor CREB-binding protein

as a coactivator of c-Myb (Dai et al.), 528-540

role in cell differentiation (Eckner et al.),

2478-2490 mediation of SREBP transcriptional

activity (Oliner et al.), 2903- 2911

Crk, phosphorylation of Sin (Alexandro- poulos and Baltimore), 1341- 1355

Crypt-villus, role of cadherins in intestinal epithelial cell migration (Hermiston et al.), 985-996

CSF. See Competence and sporulation stimulating factor


csgA branched C-factor signaling pathway

in Myzococcus (Sogaard-Ander- sen et al.), 740-754

C-signaling and traveling wave propagation in Myzococcus {Sager), 2237-2250 Review

CTD. See RNA polymerase, carboxy-terminal domain

CTR3, role of protein product in copper transport in yeast (Knight et al.), 1917-1929

cubitus interruptus activation of patched in response

Hedgehog signaling (Alexandre et al.), 2003-2013

positive regulation of araucan and caupolican (G6mez-Skarmeta and Modolell), 2935-2945

CUS1, role of gene product in spliceosome assembly (Wells et al.), 220-232

Cyclic AMP regulation of rice blast fungus M.

grisea infection (Xu and Hamer), 2696-2706

traveling wave propagation in Dictyo- stelium (Sager), 2237-2250 Re- view

Cyclin-dependent kinase inhibitors effect of p21 overexpression in trans-

genie mice (Wu et al.), 245-260 role of p21 in keratinocyte growth and

differentiation (Missero et al.), 3065-3075

Ruml inhibition of Cdc2 kinase and interaction with Cdc18 (Jalle- palli and Kelly), 541-552

vitamin D 3 induction of p21 (Liu et al.), 142-153

Cyclin-dependent kinases activation by Cdc6 during the cell

cylce (Piatti et al.), 1516-1531 cdk2 and cdk3 action in G1 (Hofmann

and Livingston), 851-861 Cdk4 as target of Cdc37 in mouse fi-

broblasts (Stepanova et al.), 1491-1502

cell-cycle regulation of SBF binding (Koch et al.), 129-141

regulation of neurite outgrowth by cdk5/p35 kinase (Nikolic et al.), 816-825

role of Xenopus Sucl homolog Xe-p9 in cell cycle control (Patra and Dunphy), 1503-1515

Cyclins cdk-dependent cyclin E ubiquitination

(Clurman et al.), 1979-1990 cell-cycle regulation through SBF

(Koch et al.), 129-141 Clb/Cdc28 in displacing SBF from pro-

moters during G2 (Koch et al.), 129-141

cyclin E requirement for E2F-induced

S phase (Duronio et al.), 2505- 2513

effect of p21 overexpression on cyclin- CDK complex activity (Wu et al.), 245-260

p53-dependent induction of cyclin G (Ko and Prives), 1054-1072 Re- view

role of cyclin E in S phase during the Drosophila endocycle (Lilly and Spradling), 2514-2526

Cyclins, D-type, coexpression of Cdc37 with cyclin D1 in proliferating cells (Stepanova et al.), 1491- 1502

Cysteine proteases role in

apoptosis (White), 1-15 Review cell-death activities in developing C.



Cytokinesis, role of drnfl/midl in positioning of division septum in fission yeast (Sohrmann et al.), 2707-2719

Cytoskeleton, role of plectin in membrane adherence (McLean et al.), 1724-1735

Danio rerio prospects for insertional mutagenesis

(Schier et al.), 3077-3080 Mini- review

role of pescadillo and dead eye in embryonic development (Allende et al.), 3141-3155

dead eye, role in zebrafish development (Allende et al.), 3141-3155

Decapentaplegic positive regulation of araucan and

caupolican (G6mez-Skarmeta and Modolell), 2935-2945

prevention of autoactivation by sog (Biehs et al.), 2922-2934

decapentaplegic, activation by Cubitus interruptus (Alexandre et al.), 2003-2013

Delta, in Drosophila wing development (Doherty et al.), 421-434

Dentate gyrus, role of TrkB and TrkC in promoting neuron survival (Minichello and Klein), 2849- 2858

Development, general cloning of a novel human kinase gene

with homology to Drosophila female sterile homeotic (Denis and Green), 261-271

effects of in vivo mutagenesis of re-

quired HoxD complex regulatory element (Gdrard et al.), 2326-2334

mechanism of hepatic specification of gut endoderm (Gualdi et al.), 1670-1682

Rasl-mediated signaling by PP2A (Wassarman et al.), 272-278

role of Heartless in Drosophila cell migra-

tion and mesodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017

lin-14 3' UTR temporal gradient formation in C. elegans (Ha et al.), 3041-3050

pescadillo and dead eye in zebrafish embryogenesis (Allende et al.), 3141-3155

p53 (Ko and Prives), 1054--1072 Re- view

Development, specific. See also Specific organisms

axial, mouse Wnt-3a gene dosage regulation (Greco et al.), 313-324

bone, role of Src-family kinases (Low- ell and Soriano), 1845-1857 Re- view

cartilage, role of p107 and p130 in mice (Cobrinik et al.), 1633- 1644

embryonic requirement for Hlx during mouse

visceral organogenesis (Hentsch et al.), 70-79

role of BMPs (Hogan), 1580-1594 Review

epithelial, role of c-ros (Sonnenberg- Riethmacher et al.), 1184--1193

eye effects on photoreceptor specifica-

tion through regulation of Lozenge role in Drosophila (Daga et

al.), 1194-1205 mouse Pax6 role (Quinn et al.), 435-

446 Rasl regulation of prospero tran-

scription in Drosophila (Kauff- mann et al.), 2167-2178

regulation by Dsrc41 in Drosophila (Takahashi et al.), 1645-1656

TFIIA role in Ras-mediated photoreceptor determination (Zeidler et al.), 50-59

hair, regulation of inductive tissue interactions by Lefl expression (Kratochwil et al.), 1382-1394

immune system, coincident regulation of cell cycle and clonality during T-cell receptor development (Hoffman et al.), 948-962

kidney abnormalities in wild-type p53

transgenic mice (Godley et al.), 836-850


regulation by Winged Helix protein BF-2 (Hatini et al.), 1467-1478


leaf, role of Glossyl5 in maize (Moose and Sisco), 3018-3027

liver, effect of p21 overexpression in transgenic mice (Wu et al.), 245-260

lymphoid, role of Src-family kinases (Lowell and Soriano), 1845- 1857 Review

male, role of FEM-2 phosphatase in C. elegans (Chin-Sang and Spence), 2314-2325

mesodermal, role of C. elegans sere-4 (Basson and Horvitz), 1953- 1965

nasal, role of mouse Pax6 (Quinn et al.), 435-446

neural opposing cell-death activities in C.



role of BMPs (Hogan), 1580-1594 Review Src-family kinases (Lowell and So-

riano), 1845-1857 Review neuronal

role of C. elegans sere-4 (Basson and Horvitz), 1953-1965

role of TrkB and TrkC in promoting neuron survival (Minichello and Klein), 2849-2858

postimplantation, abnormalities in Brcal-null mice (Liu et al.), 1835-1843

prokaryotic, branched signaling pathway in Myxococcus (Sogaard- Andersen et al.), 740-754

skeletal, role of BMPs (Hogan), 1580- 1594 Review

T-cell, cooperativity of p53 and SCID in lymphomagenesis (Nacht et al.), 2055-2066

tail bud, role of mouse Wnt-3a (Greco et al.), 313-324

tooth regulation of inductive tissue inter-

actions by Lefl expression (Kra- tochwil et al.), 1382-1394


tracheal, role of Breathless in patterning cell migration and branching in Drosophila (Lee et al.), 2912-2921

vertebrate, induction of patched by hedgehog in mice (Goodrich et al.), 301-,312

wing regulation of araucan and caupoli-

can during Drosophila pattern

formation {G6mez-Skarmeta and Modolell), 2935-2945

role of Delta in Drosophila (Doherty et al.), 421-434

Dictyostelium discoideum role of cAMP and traveling wave prop-

agation in morphogenesis (Sager), 2237-2250 Review

signal transduction regulation by ERK2 (Gaskins et al.), 118-128

dif, in Xer site-specific recombination (Blakely and Sherratt), 762-773

dif site restriction of activity in E. coli (Cornet

et al.), 1152-1161 resolvase site insertions in E. coli

(Kuempel et al.), 1162-1171; Corrigendum, 1709

Differentiation adipocyte

role of ADD1/SREBP1 (Kim and Spiegelman), 1096-1107

role of Rb interaction with C/EBPs (Chen et al.), 2794-2804

B-cell, role of p300/CBP and bHLH proteins (Eckner et al.), 2478- 2490

cellular, effects of wild-type p53 transgene expression {Godley et al.), 836-850

central nervous system, role of single factors in stem cell differentiation (Johe et al.), 3129-3140

differential adipogenic activity of multiple PPAR isoforms (Brun et al.), 974-984

effects of erythropoietin receptor gene inactivation on primitive and definitive erythropoiesis (Lin et al.), 154-164

epithelial regulation by nude locus product

Whn (Brissette" et al.), 2212- 2221

role of c-ros (Sonnenberg-Riethma- cher et al.), 1184-1193

keratinocyte, role of Src-farnily kinases (Lowell and Soriano), 1845-1857 Review

muscle, role of p3OO/CBP and bHLH proteins (Eckner et al.), 2478- 2490

of myelomonocytes induced by vitamin D 3 (Liu et al.), 142-153

myoblast, role of NAC proteins (Yotov and St-Arnaud), 1763-1772

neuronal regulation of neurite outgrowth by

cdk5/p35 kinase (Nikolic et al.), 816-.825

role of Lozenge in Drosophila (Daga et al.), 1194-1205


role of cadherins in intestinal epithe-

lium {Hermiston et al.), 985- 996

role of p53 (Ko and Prives), 1054-1072 Review

sexual, role of MIS in mammalians (Mishina et al.), 2577-2587

skeletal muscle, regulation by Rb (Zackenhaus et al.), 3051- 3064

thymocytes, p53 rescue of V(D)J rearrangement in scid mice (Bogue et al.), 553-565

DIG1 and DIG2, novel MAP kinase targets in S. cerevisiae (Cook et al.), 2831-2848

dino, role in zebrafish development IHammerschmidt et al.), 2452- 2461

dmfl/midl , role in positioning of division septum in fission yeast (Sohr- mann et al.), 2707-2719

DNA bending, role in transcriptional stimu-

lation by NHP6A/B (Paull et al.), 2769-2781

binding cooperativity of the Oct-1 POU sub-

domains (Klemm and Pabo), 27- 36

sequence specificity of B-cell coactivator OCA-B (Cepek et al.), 2079-2088

-binding domains activation of patched by Cubitus in-

terruptus in response Hedgehog signaling (Alexandre et al.), 2003-2013

altered intracellular receptor activation (Starr et al.), 1271-1283

inhibition of ATF-2 transcriptional activation (Li and Green), 517- 527

breaks, double-stranded, activation of DNA damage checkpoint by V(D)] recombination (Guidos et al.), 2038-2054

damage in ATM-deficient mice (Xu et al.),

2411-2422 p53 levels and extent of tumor cell

apoptotic response (Chen et al.), 2438-2451

parallel sensory branches for signaling in S. cerevisiae tNavas et al.), 2632-2643

role of p53 in radiation-induced differentiation in scid mice (Bogue et al.), 553-565

and Spkl/Rad53 regulation by Mecl-dependent protein phosphorylation (Sun et al.), 395-406

helicases, role of XPB and XPD in p53- dependent apoptosis (Wang et al.), 1219-1232

methylation, role

GENES & D E V E L O P M E N T 3233

in activation of Xist (Panning and Jaenisch), 1991-2002

in establishing genomic imprinting (Tucker et al.), 1008-1020

of Lon protease in Caulobacter (Wright et al.), 1532-1542

methyltransferase, activity during oogenesis and spermatogenesis (Tucker et al.), 1008-1020

polymerase ~, parallel sensory branches for signaling in S. cerevisiae (Navas et al.), 2632- 2643

protein kinase activation of DNA damage check-

point by V(D)! recombination in scid mice (Guidos et al.), 2038- 2054


repair bypass of scid defect by induction of

p53 DNA damage response pathways (Bogne et al.), 553- 565

effects of ATM gene inactivation (Xu and Baltimore), 2401- 2410

encoding of Ku p70 homolog IRBP by Drosophila mus309 (Beall and Rio), 921-933

p53 role (Ko and Prives), 1054-1072 Review

XPB and XPD roles in p53-dependent apoptosis (Wang et al.), 1219-1232

replication parallel sensory branches for DNA

damage signaling in S. cerevisiae (Navas et al.), 2632-2643

promotion by Cdc6 during the cell cycle (Piatti et al.), 1516-1531

regions of yeast RPA subunits with similarity to E. coli SSB protomer (Philipova et al.), 2222- 2233

regulation and specification of eukaryotic origins (Diffley), 2819- 2830 Review

Spk 1 / Rad53 regulation by Mec 1-dependent protein phosphorylation (Sun et al.), 395-406

ribosomal, role of TBP in expression in S. cerevisiae (Steffan et al.), 2551-2563

topoisomerases, role in mitotic chromosome condensation in S. cerevisiae (Castafio et al.), 2564- 2576

DNA-PK. See DNA protein kinase Domains, chromosomal, determinants

of late origin activation in yeast (Friedman et al.), 1595-1607

Dominant-negative mutants cdk2 and cdk3 cell cycle function

(Hofmann and Livingston), 851- 861

regulation of neurite outgrowth by cdk5/p35 kinase (Nikolic et al.), 816--825

role of ADD1/SREBP1 in adipocyte differentiation (Kim and Spiegelman), 1096-1107

Dorsal, activation by Toll, tube, and pelle (Norris and Manley), 862-872

Dorsal closure, mediation by Drosophila JNK pathway (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759-2768

Dorsal-ventral axis, prevention of Dpp autoactivation by Drosophila sog (Biehs et al.), 2922-2934

Double-strand break repair, role in intron mobility (Mueller et al.), 351-364

doublesex, assembly of specific SR protein complexes at the splicing enhancer (Lynch and Maniatis), 2089-2101

Drl, corepressor requirement (Mermel- stein et al.), 1033-1048

Drl-associated polypeptide 1, requirement for Drl-mediated repression (Mermelstein et al.), 1033- 1048

DRAP1. See Drl-associated polypeptide 1

Drosophila activation of dorsal by Toll, tube, and

pelle (Norris and Manley), 862- 872

assembly of specific SR protein complexes at the doublesex splicing enhancer (Lynch and Maniatis), 2089-2101

binding of TFIID to downstream basal promoter element (Burke and Kadonaga), 711-724

cloning of a novel human kinase gene with homology to female sterile homeotic (Denis and Green), 261-271

compensatory signaling sites on Torso (Cleghon et al.), 566-577

cyclin E requirement for E2F-induced S phase (Duronio et al.), 2505- 2513

degradation of maternal mRNAs in maternal/zygotic transition (Edgar and Datar), 1966-1977

E-cadherin in epithelial cell rearrangement (Uemura et al.), 659-671; (Tepass et al.), 672-685

encoding of bHLH-PAS protein by trachealess

(Wilk et al.), 93-102 Ku p70 homolog IRBP by DNA re-

pair mutant mus309 (Beall and Rio), 921-933

Fab-7 attenuation of enhancer-promoter interactions in (Zhou et

al.), 3195-3201 gradual activation of transcription dur-

ing embryogenesis (Pritchard and Schubiger), 1131-1142

independent regulation of neighboring genes (Merli et al.), 1260--1270

induction of S phase and apoptosis by ectopic E2F expression in Drosophila (Asano et al.), 1422- 1432

intercellular signaling and polarization of body axes during oogenesis (Ray and Sch6pbach), 1711- 1723 Review

JNK pathway mediating morphogenesis and an immune response (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759- 2768


prevention of Dpp autoactivation and suppression of neurogenesis by sog (Biehs et al.), 2922-2934

Rasl regulation of prospero transcription during eye development (Kauffmann et al.), 2167-2178

RB-related gene RBF (Duet al.), 1206-- 1218

regulation of eye development by Dsrc41 (Taka-

hashi et al.), 1645-1656 Rasl-mediated signaling by PP2A

(Wassarman et al.), 272-278 rescue of labial null by chicken or-

tholog Hoxb-1 (Lutz et al.), 176- 184

role of Breathless in patterning cell migra-

tion and branching in the tracheal system (Lee et al.), 2912- 2921

CF2 in EGF-R-activated dorsoventral patterning (Hsu et al.), 1411-1421

grim in cell death (Chen et al.), 1773-1782

Heartless in cell migration and mesodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017

Lozenge in eye development (Daga et al.), 1194-1205

plx in tracheal function (Zhang et al.), 1108-1119

porcupine in Wingless processing (Kadowaki et al.), 3116-3128

short-range repressors in regulation of complex loci (Gray and Levine), 700-710

TFIIA during RAS-mediated photoreceptor determination (Zeidler et al.), 50-59

trachealess in embryonic tube formation (Isaac and Andrew), 103-117


Reviewers, Volume 10" (1996) The editors would like to thank the Editorial Board and the following scientists who were kind enough to review papers and provide advice during 1996.

*From October 18, 1995 to October 17, 1996

Adler, Paul Allshire, Robin Alt, Fred Alwine, James Ammerer, Gustave Anderson, David Anderson, Kathryn Anderson, Phillip Andrews, Brenda Ares, Manuel Arndt, Kim Artavanis-Tsakonas,

Spyridon Artzt, Karen Ashburner, Michael Austin, Stuart Ausubel, Frederick Avery, Leon Avner, Philip Baker, Tania Baldwin, Albert, Jr. Baltimore, David Bannerjee, Utpal Banuett, Flora Barbacid, Mariano Bardwell, James Bargmann, Cori Barlow, Denise Barres, Barbara Bartolomei, Marisa Barton, Mary K. Basler, Konrad Bate, Michael Beach, David Beato, Miguel Becker, Peter Beddington, Rosa Beggs, Jean Behringer, Richard Bell, Steve Benezra, Robert Benson, Spencer Berget, Susan Berk, Arnold Bernards, Rene Bernstein, Alan Berry, Marla Besmer, Peter Beug, Hartmut Bickmore, Wendy Bienz, Marianne Bier, Ethan Bingham, Paul Bird, Adrian

Bishop, Douglas Black, Douglas Blackwell, Keith Blobel, Gunter Blumenthal, Thomas Bock, August Bodmer, Rolf Boeke, Jeff Bohmann, Dirk Bolen, Joseph Botchan, Michael Bothwell, A1 Bouck, Noel Brady, Scott Brandriss, Marjorie Bravo, Rodrigo Brent, Rodger Brewin, Nick Brockdroff, Neil Buckingham, Margaret Buratowski, Stephen Burden, Steven Burgoyne, Paul Burley, Stephen Butler, Mark Cantley, Lewis Capecchi, Mario Carey, Michael Carlson, Marian Carr, Anthony Carroll, Sean Cashmore, Tony Cedar, Howard Chandler, Vicki Chant, John Chater, Keith Chen, Jasmine Cho, Ken Chorey, Joanne Clayton, David Cleary, Michael Coen, Donald Coffin, John Cole, Charles Collins, Kathy Cooley, Lynn Corces, Victor Corey, Suzanne Costantini, Frank Courey, Albert Crabtree, Gerald Craig, Elizabeth Craig, Nancy Cross, Frederick Damsky, Caroline Dangl, Jeff Darnell, James Darnell, Robert Davies, Kay de Lange, Titia Deng, Xiong-W DeRobertis, Eddy Desplan, Claude Dixit, Vishva

Donahue, Thomas Donehower, Lawrence Draetta, Giulio Dreyfuss, Gideon Driever, Wolfgang Drubin, David Duboule, Denis Dunn, Ashley Dunphy, William Dynlacht, Brian Dyson, Nicholas Dzierzak, Elaine Ebright, Richard Eisenman, Robert Elgin, Sally Elion, Elaine Emerson, Beverly Engel, Douglas Ephrussi, Anne Errington, Jeffrey Ewen, Mark Farmer, Stephen Fearon, Eric Felsenfeld, Gary Firtel, Richard Fishman, Mark Flavell, Richard Franke, Werner Frasch, Manfred Freedman, Len Freidberg, Errol Friend, Stephen Fuchs, Elaine Furuya, Masaki Gall, Joseph Galloway, Denise Geiduschek, Peter Gerace, Larry Gibbs, Clarence Gilman, Michael Glass, Christopher Glover, David Gober, James Goff, Stephen Gold, Lawrence Goldfarb, Mitchell Goldstein, Joseph Goodman, Richard Gordon, Colin Gorovsky, Martin Gottschling, Daniel Grabowski, Paula Gralla, Jay Graves, Barbara Green, Michael Greenblatt, Jack Greenwald, Iva Greider, Carol Gridley, Thomas Griep, Anne Groner, Bernard Grossman, Alan Grummt, Ingrid Grunstein, Michael


Gruss, Peter Guthrie, Chris Haber, James Hahn, Steven Hake, Sarah Hall, Alan Hanahan, Doug Hannon, Gregory Hannun, Yosef Hargreaves, John Harper, Wade Harrison, Stephen Hartenstein, Volker Haselkorn, Robert Hauschka, Stephen Hawley, Scott Hayday, Adrian Hearing, Patrick Hengartner, Michael Henikoff, Steve Hernandez, Nouria Herskowitz, Ira Higgs, Doug Hill, Robert Hinnebusch, Alan Hinton, Barry Hirano, Tatsuya Hoch, James Hoeijmakers, Jan Hoffman, Michael Hogan, Brigid Holder, Nigel Holmgren, Robert Hope, Ian Howley, Peter Hoyt, Andrew Hughes, Steve Hunter, Tony Hurt, Edward Hurwitz, Jerard Hyman, Linda Hynes, Richard Ihle, James Ingraham, Holly Ish-Horowicz, David Jacks, Tyler Jackson, Ian Jackson, Stephen Jacobson, Alan Jackle, Herbert Jaenisch, Rudolph Jentsch, Stefan Jessen, Kristijian Johnson, Gary Johnson, Peter Johnson, Reid Johnston, Lee Johnston, Mark Jones, Katherine Joyner, Alexandra Jurgens, Gerd Kahmann, Regine Kalderon, Dan Kaplan, Jerry Karpen, Gary Kastan, Michael

Kaufman, Paul Keller, Walter Kenyon, Cynthia Kessin, Richard Kidwell-Brown, Margaret Kim, Stuart Kimelman, David Kimmel, Alan Kimmel, Charles Kingsley, David Kingston, Robert Kinmer, Christopher Klein, Hannah Kolodner, Richard Konderosi, Adam Konopka, James Koopman, Peter Korsmeyer, Stanley Kowalcykowski, Stephen Krainer, Adrian Krasnow, Mark Krumlauf, Robb Kustu, Sydney Lamond, Angus Landy, Art Lane, Daniel Lane, David Lassar, Andrew Lazenbnik, Yuri Leavitt, Andrew Leder, Phil Lee, David Lees, Jackie Lehmann, Alan Lehner, Christian Lemke, Greg Leptin, Maria Levin, David Levine, Arnold Levy, David Lewis, Susanna Lis, John Losick, Richard Lovell-Badge, Robin Lowe, Scott Lowry, Douglas Luhrmann, Reinhard Lustig, Art Lyon, Mary Maas, Richard MacDonald, Paul MacLeod, K. Maizels, Nancy Mak, Tak Malim, Michael Mangelsdorf, David Maniatis, Tom Mann, Jeffrey Marshall, Chris Martin, David Massague, Joan Mathews, Michael Mattaj, Iain Matthias, Patrick Meinke, David Melton, Doug

Mendenhall, Michael Miller, Lois Mirsky, Rhona Mitchell, Aaron Mizuuchi, Kiyoshi Mlodzik, Marek Model, Peter Modolell, Juan Mohun, Tim Moon, Randall Moore, Melissa Morimoto, Richard Moses, Harold Moses, Kevin Moss, Tom Murray, Andrew Murre, Cornelius Nabel, Gary Nasmyth, Kim Neuberger, Michael Neufeld, Elizabeth Nevins, Joseph Newlon, Carol Newman, Andrew Newport, John Nilsen, Timothy Niswander, Lee Nomura, Masayasu Nurse, Paul Nusse, Roel O'Farrell, Patrick Olson, Eric Oren, Moshe Orkin, Stuart Oft-Weaver, Terry Pabo, Carl Pace, Norman Parker, Malcolm Parker, Peter Parker, Roy Parkinson, Sandy Paro, Renato Parslow, Tristan Pavletich, Nikola Pendergast, Ann Marie Perlman, Philip Perlmann, Thomas Perrimon, Norbert Peterson, Craig Pfahl, Magnus Phillips, Simon Pillus, Lorraine Poellinger, Lorenz Polakis, Paul Posakony, James Priess, James Pringle, John Proudfoot, Nicholas Ptashne, Mark Pugh, B. Franklin Quail, Peter Rabbitts, Terry Raff, Martin Rajewsky, Klaus Ramakrishnan, Venki Reed, Robin


Reed, Steve Reeder, Ronald Reik, Wolf Reinberg, Danny Reines, Daniel Reznikoff, William Rice, Andrew Rigby, Peter Rine, Jasper Rio, Donald Roberts, James Robertson, Elizabeth Roeder, Robert Rong, Li Roop, Dennis Rorschneider, Lawrence Rosbash, Michael Rose, Mark Rosenberg, Naomi Rosenfeld, M. Geoff Rossant, Janet Rushlow, Christine Russell, Marjorie Russell, Paul Ruvkun, Gary Rymond, Brian Sachs, Alan Sandmeyer, Suzanne Sanes, Josh Sarnow, Peter Schechter, Alan Schedl, Andreas Schedl, Paul Schedl, Timothy Schlessinger, Joseph Schfipbach, Trudi Schwab, Martin Schwarz-Sommer,

Zsuzsanna Scott, Matthew Semenza, Gregg Shackleford, Gregory Shilo, Ben-Zion Shimkets, Lawrence Shimura, Yoshiro Shore, David Siebenlist, Ulrich Sigler, Paul Silhavy, Thomas Silver, Pamela Simons, Kai Simpson, Patricia Simpson, Robert Singh, Harinder Sive, Hazel Skene, Barbara Skowronski, Jacek Slack, Jonathan Smale, Steven Smith, Jim Smith, Mitchell Snyder, Michael Sollner-Webb, Barbara Sorger, Peter Speck, Nancy Speigelman, Bruce

Spradling, Allan Sprague, George St. Johnston, Daniel Stadtman, Theresa Stark, Mike Staskawicz, Brian Stellar, Hermann Stenlund, Arne Sternberg, Paul Sternglanz, Rolf Stillman, Bruce Strasser, Andreas Strickland, Sidney Struhl, Gary Struhl, Kevin Studer, Michelle Stunnenberg, Henk Surani, Azim Tessier-Lavigne, Marc Thomas, Christopher Thompson, Craig Thummel, Carl Tollervey, David Tomlinson, Andrew Treisman, Richard Tryggvason, Karl Tye, Bik-Kwoon Ullu, Elizabetta Van Aelst, Linda Van Dyke, Terry van Heyningen, Veronica Varmus, Harold Vennstrom, Bjorn Verma, Inder Vogt, Peter Wagner, Erwin Wahl, Geoffrey Walbot, Virginia Wasserman, Steven Weber, Klaus Weigel, Detlef Weinberg, Robert Weinert, Ted Weissman, Charles Weissman, Irving Wensink, Peter West, Stephen Westerfield, Monte Weston, Kathleen White, Eileen White, Rob Wickens, Marvin Wieczorek, Helmut Wieschaus, Eric Willison, Keith Winston, Fred Wisniewski, Henryk Witte, Owen Wolffe, Alan Wong, Winnie Wood, Richard Wormington, Michael Wright, Christopher Yamamoto, Keith Yanagida, Mitsuhiro Yaniv, Moshe

Yanofsky, Martin Young, Richard Yuspa, Stuart Zakian, Virginia Ziff, Edward Zinn, Kai


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Author Index, Volume 10 (1996) Abrams, J.M., 1773 Adams, J.M., 70 Adler, H.S., 1455 Aebersold, R., 1084 Aguilar-Cordova, E., 553 Ahringer, J., 1120 Akimani, H., 528 Alarcon, C.M., 279 Alexandre. C., 2003 Alexandropoulos, K., 1341 Algate, P.A., 1084 Allende, M.L., 3141 Alley, M.R.K., 1532 Alwine, J.C., 325, 1369 Alzhanova-Ericsson, A.T.,

2881 Amano, S., 1724 Amberg, D.C., 1608 Ammeter, G., 129 Amsterdam, A., 3141 Anderson, J.E., 1173 Andresen, J.M., 2903 Andrew, D.J., 103 Apone, L.M., 2368 Arber, S., 289 Ares, M., Jr., 220 Arndt, K.T., 1904 Arroyo, E., 1751 Asano, M., 1422 Ashley, T., 2411, 2423 Assa-Munt, N., 16 Aubry, L., 118 Azpiazu, N., 3183 Badiani, P., 2732 Bagni, C., 1411 Bai, Y., 2025 Baker, J.C., 1880 Baltimore, D., 963, 1341,

2401, 2411 Banerjee, U., 1194 Barberis, A., 2359 Bardwell, L., 2831 Barolo, S., 3195 Barrett, T., 2732 Basson, M., 1953 Baumeister, R., 1395 Beach, D., 1633 Beall, E.L., 921 Beard, C., 1008 Beaulieu, N., 1930 Becker, T., 3141 Behringer, R.R., 2577 Beijersbergen, R.L., 2969 Beiman, M., 2993 Belfort, M., 351, 2158 Bentley, N.J., 2423 Berget, S.M., 208 Bergstrom, D.E., 1260 Berk, A.J., 2491 Bermingham, J.R., Jr., 1751 Bernards, R., 2969 Beug, H., 2462 Biehs, B., 2922 Bier, E., 2922

Birchmeier, C., 1184 Bitgood, M.J., 647 Blackburn, E.H., 1822 Blackman, R.K., 1260 Blakely, G., 762 Blatter, E.E., 16 B6hm, T., 1516 Boeke, J.D., 620 Bogue, M.A., 553 Boise, L.H., 2621 Bommakanti, M., 129 Bonten, E., 3156 Boscheron, C., 1796 Bossard, P., 1670 Bouhidel, K., 1812 Bowman, T., 826 Brainerd, E.E., 2411, 2423 Brass, A.L., 2335 Breitwieser, W., 2179 Brewer, B.J., 1595 Brill, S.J., 2222 Brissette, J.L., 2212 Broach, J.R., 382, 1021 Brodbeck, C., 2707 Brody, M.S., 2265 Bronson, R.T., 1621, 1633,

2055, 2411 Brook, A., 2505 Brown, J.D., 2805 Brown, S.A., 1479 Brun, R.P., 974 Bryant, G.O., 2491 Brzoska, P.M., 2564 Buck, S.W., 1297 Bullrich, F., 1724 Bunker, C.A., 905 Burgeson, R.E., 1724 Burke, T.W., 711 Burley, S.K., 2491 Burson, L.M., 887 Cairns, B.R., 2117, 2131 Camper, S.A., 313 Cannon, K., 37 Cao, J., 1049 Cao, Z., 37 Cardenas, M.E., 279 Carey, M., 2540, 2769 Carlberg, K., 1084 Carlson, M., 3105 Caroni, P., 289 Cart, A.M., 2423 Carthew, R.W., 2167 Castaflo, I.B., 2564 Cate, R.L., 2577 Cech, T.R., 2870 Cepek, K.L., 2079 Chambon, P., 80, 2326 Chan, Y.R., 2055 Chang, H.C., 272 Chang, J., 777 Chao, D.T., 2859 Chasman, D.I., 2079 Chen, H., 2564 Chen, J., 974

Chen, J.-Y., 2326 Chen, P., 1773 Chen, P.-L., 2794 Chen, X., 2438 Chen, Y., 2794 Cheng, G., 963 Chi, T., 2540 Chin, W., 80 Chin-Sang, I.D., 2314 Christenson, E.R., 2423 Christiano, A.M., 1724 Christman, M.F., 2564 Chung, D., 3051 Clark, A.M., 118 Clarkin, K.C., 934 Cleghon, V., 566 Clurman, B.E., 1979 Clyman, J., 351 Cobrinik, D., 1633 Cocker, J.H., 1516 Coffer, P., 1455 Cohen, J.B., 338 Cohen, M., 129 Cohen-Fix, O., 3081 Cole, C.N., 1608 Coleman, J.R., 1670 Colot, H.V., 1699 Cook, J.G., 2831 Copeland, T.D., 566 Cornet, F., 1152 Cosgrove, D., 2981 Costantini, F., 154 Coursen, J.D., 1219 Crabtree, G.R., 2117 Craig, N.L., 2145 Crespo, P., 1455 Crompton, T., 948 Cygan, J.A., 1260 Daga, A., 1194 D'Agati, V.,- 154 Dahanukar, A., 2610 Dai, P., 528 Damania, B., 1369 Dancholt, B., 2881 Danska, J.S., 2038 Darlington, G.J., 804 Dash, A.B., 1858 Datar, S.A., 1966 Dausman, J., 1008 Davis, R.J., 2732 d'Azzo, A., 3156 De Baere, I., 755 Ddcimo, D., 80 DeArmond, S.J., 1736 DeBoy, R.T., 2145 Decatur, A.L., 2348 Degenstein, L., 165 Deng, K., 1657 Denis, G.V., 261 Desbarats, L., 447 Devine, S.E., 620 1)i Como, C.J., 1904 Di Cunto, F., 3065 Di Leonardo, A., 934

Dierich, A., 80 Diffley, J.F.X., 1516, 2819 Diller, J.D., 1595 Dodd, J.A., 887, 2551 Doe, C.Q., 3003 Doherty, D., 421 Dominski, Z., 3028 Donaldson, T., 2302 Donehower, L.A., 553 Dotto, G.P., 2212, 3065 Doucas, V., 196 Drouin, J., 1284 Du, W., 1206 Duboule, D., 2326 Dudek, H., 816 Dugich-Djordjevic, M.M.,

3129 Dull, M., 1382 Dumstrei, K., 1194 Dunphy, W.G., 1503 Duronio, R.J., 2505 Dyson, N., 1206, 1621, 1633,

2505 Eady, R.A.J., 1724 Eagelson, K., 1049 Ebright, R.H., 16 Eckhaus, M., 836 Eckner, R., 2478 Edgar, B.A., 1966 Edmondson, D.G., 1247 Eichele, G., 176 Eidemiller, J., 185 Eilers, M., 447 Eisenbeis, C.F., 2335 Elledge, S.J., 2632 Ellis, R., 974 Elmore, L., 1219 Endo, S., 1645 Ephrussi, A., 2179 Erdjument-Bromage, H., 1049 Errington, J., 794 Evans, R.M., 196, 974 Fangman, W.L., 1595 Fankhauser, C., 2707 Fantino, E., 887 Farifias, I., 1382 Farrell, S., 2359 Fay, D.S., 395 Feger, G., 421 Feld, R., 244 Ferguson, B.M., 1595 Ferguson, K.C., 1543 Fernandez-Salguero, P., 60 Feucht, A., 794 Field, D.J., 489 Fiering, S., 185 Filosi, N., 407 Finegold, M.J., 2577 Firtel, R.A., 118 Fischer, D., 1143 Fisher-Adams, G., 686 Fitzsimmons, D., 2198 Flaggs, G., 2423 Flesken-Nikitin, A., 1835

GENES & D E V E L O P M E N T 3223

Foiani, M., 395 Forman, B.M., 974 Fomerod, M., 3156 Forrester, K., 1219 Fox, C.H., 60 Frampton, J., 2720 Francois, V., 2922 Frasch, M., 3183 Fraser, P., 2894 Fredericks, W.J., 2067 Freedman, L.P., 129 Friedman, J.R., 2067 Friedman, K.L., 1595 Friend, S., 2382 Friesen, J.D., 489 Fritz, A., 2759 Fuchs, E., 165 Gaal, T., 16 Gagel, R.F., 208 Gaiano, N., 3141 Galceran, J., 1382 Gallagher, P.A., 2167 Gallie, B.L., 3051 Gansmuller, A., 80 Garrett, K., 1173 Gaskins, C., 118 Gasser, S.M., 1796 Gaubatz, S., 447 Gauthier, Y., 1284 Gayko, U., 566 G6rard, M., 2326 Geiduschek, E.P., 725 Gibson, M., 1219 Gilson, E., 1297, 1796 Girard, L., 1930 Gish, B., 1773 Gisselbrecht, S., 3003 G6mez-Skarmeta, J.L., 2935 G6decke, S., 1184 Godley, L.A., 836 Gonzalez, F.J., 60 Goodrich, L.V., 301 Gordon, J.I., 985 Gotta, M., 1796 Gourse, R.L., 16 Gozani, O., 244 Graf, T., 2720 Grallert, B., 2644 Grandal, I., 2038 Gray, S., 700 Greco, T.L., 313 Green, M.R., 261, 517, 2368 Gribnau, J., 2894 Grisham, J., 245 Grondona, J.M., 80 Gronemeyer, H., 2326 Gross, C.A., 3170 Grosschedl, R., 1382 Grossman, A.D., 2014 Grosveld, F., 2894 Grosveld, G., 3156 Groudine, M., 185, 1979 Grumbling, G., 2302 Grunkemeyer, J.A., 2981 Grunstein, M., 686, 1327 Gruszynski-DeFeo, E., 672

Gu, C., 2222 Gu, L., 826 Gualdi, R., 1670 Guermah, M., 2389 Guidos, C., 2038 Guo, L., 165 Gutkind, J.S., 1455 Ha, I., 3041 Haag, T.A., 672 Hacohen, N., 2912 Hafen, E., 2759 Haga, T., 1736 Hagman, J., 2198 Hagstrom, K., 3202 Hamada, Y., 1670 Hamer, J.E., 2696 Hammerschmidt, M., 647,

2452 Han, J., 461 Han, Z., 2732 Hanahan, D., 2105 Hanna, Z., 1930 Hannon, G., 1633 Hansen, S.K., 2903 Hara, Y., 60 Harkness, T.A.A., 686 Harland, R.M., 1880 Harlow, E., 1621, 1633 Harper, J.W., 1491 Harris, A.W., 2055 Harris, C.C., 1219 Hartenstein, V., 672 Hartley, L., 70 Harvey, R.P., 70 Hateboer, G., 2969 Hatini, V., 1467 Hawley, R.S., 2383 Hayashi, S., 659 Hayday, A.C., 948 Haynes, M., 220 Hazel, T.G., 3129 He, T.-C., 1945 Heid, p.J., 1543 Heintz, N., 2389 Heitman, J., 279 Henderson, D.W., 1455 Hengge-Aronis, R., 1143 Henry, M., 1233 Hentsch, B., 70 Hermiston, M.L., 985 Herzlinger, D., 1467 Hill, R.E., 435 Hinman, A., 2971 Hogaard, A., 1162 Hodsdon, W., 2198 Hoeijmakers, J.H.J., 1219 Hoekstra, M.F., 2423 Hoemann, C., 1930 Hoffman, E.S., 948 Hoffmann, A., 2389 Hofmann, F., 851, 2949 Hogan, B.L.M., 1580, 1657 Holmes, S.G., 1021 Holtzman, D.A., 2423 Hopkins, N., 3141 Hopper, A.K., 1608


Hoppler, S., 2805 Horstmann, H., 2179 Horvitz, H.R., 578, 1073,

1289, 1953 Hou, D.-X., 528 Hsu, T., 1411 Hu, M.C.-T., 2251 Huang, E., 1433 Huang, M.T.F., 2038 Huang, X.-P., 2067 Huang, Y.-J., 351 Hudson, D.L., 1724 Huh, S.O., 1467 Hunter, W.J., 2981 Hwang, D.-Y., 338 Igel, H., 220 Imbalzano, A.N., 905, 1479 Ingham, P.W., 2003 Ingledue, T.C., III, 3028 Inostroza, J.A., 1049 Ip, Y.T., 2732 Irish, V.F., 1812 Isaac, D.D., 103 Ishii, S., 528 Ishov, A.M., 196 Izaurralde, E., 1683 Jacinto, A., 2003 Jacks, T., 1621, 1633, 2055 Jackson-Grusby, L., 1008 Jaenisch, R., 1008, 1991 Jallepalli, P.V., 541 Jan, L.Y., 421 Jan, Y.N., 421 Jarmolowski, A., 1683 Jayaraman, L., 2438 Jenni, M., 2759 Jensen, D.E., 2067 Jia, X., 16 Jiang, R., 3105 Jiang, Y.W., 604 Jiang, Z., 3051 Joazeiro, C.A.P., 725 Johe, K.K., 3129 Johnson, R.C., 2769 Johnson, R.L., 301 Jolicoeur, P., 1930 Jones, K.A., 37 Jones, N., 2289 Josso, N., 2577 Joyner, A.L., 3077 Juguilon, H., 196 Kablar, B., 1173 Kadonaga, J.T., 37, 711 Kadowaki, T., 3116 Kafatos, F.C., 1411 Kaiser, D., 740 Kalla, K.A., 1751 Kamimura, J., 2212 Kane, M.F., 407 Kanei-Ishii, C., 528 Kang, C.M., 2265 Karim, F.D., 272 Karlovich, C.A., 1194 Karrim, J., 2105 Kassavetis, G.A., 725 Kassis, J., 1108

Kastner, P., 80 Kataoka, Y., 659 Kauffmann, R.C., 2167 Kaufman, T.C., 176 Kaufmann, J., 873 Kawakami, K., 3141 Ke, N., 634 Keck, J.G., 37 Keegan, K.S., 2423 Kehrli, E., 2335 Kelly, T.J., 541 Kerkhoven, R.M., 2969 Kerr, K., 2600 Keys, D.A., 887, 2551 Kieser, A., 1455 Kim, J.B., 1096 Kim, J.M., 634 Kimelman, D., 1433 Kimsey, H., 740 Kimura, S., 60 Kingston, R.E., 905, 1479,

2782 Kinzler, K., 1945 Kirschner, M.W., 3081 Kiseleva, E., 2881 Kiyokawa, H., 3065 Klein, R., 2849 Klemm, J.D., 27 Klingensmith, J., 3116 Knauf, U., 2782 Knight, S.A.B., 1917 Knowles, G., 2038 Ko, L.J., 1054, 2438 Kobayashi, M., 1783 Koch, C., 129 Koff, A., 948, 3065 Kojima, T., 1645 Kolch, W., 1455 Kolodner, R., 407, 1433 Kondo, K., 1783 Kopp, J.B., 836 Kornak, J.M., 2981 Kornberg, R.D., 2131 Korsmeyer, S.J., 2859 Koshland, D., 3081 Kosman, D.J., 1917 Kowalczykowski, S.C., 1890 Kozak, C.A., 1930 Krall, L., 245 Krasnow, M., 2912 Kratochwil, K., 1382 Kraut, R., 659 Kremmer, E., 1455 Krezel, W., 80 Krishnan, V.V., 16 Kron, S.J., 2831 Kuempel, P., 1162 Kuo, A., 2117 Kwon, L.F., 1917 Kwon, Y.T., 816 Kyriakis, J., 2782 LabbG S., 1917 Labosky, P.A., 1657 Lagrange, T., 2657 Lai, E., 1467 Laird, P.W., 1008

Lamonerie, T., 1284 Lanct6t, C., 1284 Landsman, D., 1049 Lane, E.B., 1724 Lawrence, P.A., 3183 Lazazzera, B.A., 2014 Lee, B.-S., 887 Lee, D., 2212 Lee, M.-H., 129, 1621, 1633 Lee, M.S., 1233 Lee, T., 2912 Lee, W.-H., 1835, 1870, 2794 Lehmann, R., 3077 Lei, H., 1008 Leid, M., 80 Leigh, I.M., 1724 Leng, X., 1491 Leu, T.M.J., 948 Levin, P.A., 478 Levine, A.J., 2971 Levine, M., 700, 3195 Levinson, R.S., 2131 Levitt, P., 1049 Lewis, J.D., 1683 Li, B., 1310 Li, E., 1008 Li, J., 2212 Li, R., 70 Li, S., 1835 Li, S., 2167 Li, X.-Y., 517 Liaw, L., 1657 Lilly, M.A., 2514 Lira, S.-K., 154 Lin, C.-S., 154 Ling, X., 686 Linke, S.P., 934 Lints, T.J., 70 Lioubin, M.N., 1084 Liu, C.-Y., 1835 Liu, M., 129 Liu, X.-D., 592 Liu, Y., 1395 Livingston, D.M., 851, 2478,

2949 Lobel, L., 2189 Losick, R., 478, 2348 Lou, H., 208 Louarn, J., 1152 Louarn, J.-M., 1152 Lowell, C.A., 1845 Lu, H.-C., 176 Lu, J., 2222 Lu, Q., 1327 Lundblad, V., 3094 Lupold, S.E., 1219 Lustig, A.J., 1310 Lutz, B., 176 Lutz, C.S., 325 Lynch, K.W., 2089 Lyons, I., 70 Ma, X.-J., 1327 Macdonald, P.M., 2600 Madden, K., 777 Magis, W., 185 Magnin, T., 794

Maillet, L., 1796 Maira, S.-M., 2198 Majerus, P.W., 1051 Maniar, H.S., 2222 Maniatis, T., 1356, 2089 Manley, I.L., 325, 862, 1569,

2588 Marcand, S., 1297, 1796 Marini, F., 395 Mark, M., 80 Markussen, F.-H., 2179 Marsischky, G.T., 407 Martel, L.S., 2491 Martelli, F., 2949 Marth, J.D., 3051 Martin, D.I.K., 185 Marzluff, W.F., 3028 Matsui, W., 1271 Mattaj, I.W., 1683 Matzuk, M.M., 2577 Maul, G.G., 196 McEachern, M.]., 1822 McGonigle, B., 1812 McGrath, J.A., 1724 McGuigan, C., 1683 McKay, R.D.G., 3129 McKnight, S.L., 367 McLean, W.H.I., 1724 McMahon, A.P., 313, 647,

2452 McMahon, I.A., 301,313 McMillan, J.R., 1724 Meehan, D.T., 2981 Megeney, L.A., 1173 Mellerick, D.M., 1108 Merli, C., 1260 Mermelstein, F., 1049 Meyer, C.F., 2251 Meyn, M.S., 2411, 2423 Michaud, N.R., 2.684 Michelson, A.M., 3003 Milenkovic, L., 301 Millar, J.B.A., 2289 Miller, D., 176 Miller, J.R., 1433, 2527 Milliman, C.L., 2859 Minichiello, L., 2849 Minn, AJ., 2621 Mischak, H., 1455 Mishina, Y, 2577 Missero, C., 3065 Mitchell, P., 502 Miyake, T., 1783 Mlodzik, M., 50 Modha, D., 461 Modolell, J., 2935 Montell, D.J., 2912 Moon, R.T., 1433, 2527, 2805 Moose, S.P., 3018 Moretti, P., 1297 Morris, D.K., 3094 Morrison, D.K., 566, 2684 Moss, S.B., 2423 Mueller, J.E., 351, 2158 Muffler, A., 1143 Mukai, S., 1621

Mullen, J.R., 2222 Muller, M., 3202 Muller, T., 3129 Mulligan, G., 1621, 1633 Murayama, A., 1783 Murphy, M., 2971 Murthy, K.G.K., 325 Mushinski, I.F., 1455 Nacht, M., 2055 Nagappan, O., 1162 Naik, P., 2105 Nakanishi, M., 804 Nasmyth, K., 129, 1516 Navas, T., 2632 Neilson, E.G., 2067 Ness, S.A., 1858 Neville, M., 220 Nevins, J.R., 1422 Newhouse, M.W., 313 Newton, E.M., 2782 Nguyen, T.T., 887 Nickels, J.T., 382 Nielsen, M., 1162 Nikitin, A.Yu, 1870 Nikolic, M., 816 Nogi, Y., 887 Nomura, M., 887, 2551 Nordstrom, W., 1773 Norris, J.L., 862 Nuez, B., 2894 Nurse, P., 2644 Nyland, S.V.M., 1595 O'Connell, S., 1751 O'Connor, J.P., 325 Oda, H., 659 Odenwald, W.F., 1108 O'Farrell, P.H., 2505 Oft, M., 2462 Ohno, M., 997 Olde, B., 1108 Oldread, E., 2478 Oliner, J.D., 2903 Omatyar, L., 672 Oren, M., 826 Orphanides, G., 2657 Orrico, F.C., 1858 Owaribe, K., 1724 Owen, M.J., 948 Owens, J., 836 Pabo, C.O., 27 Paglino, l.J., 836 Panning, B., 1991 Parker, M.M., 351 Parker, S.B., 1491 Passoni, L., 948 Patra, D., 1503 Patte, J., 1152 Paull, T.T., 2769 Pazin, M.J., 37 Peli, l., 2462 Perez, D., 461 Perkins, L.A., 566 Perrimon, N., 566, 3116 Peters, J.-M., 3081 Petfalski, E., 502 Philipova, D., 2222

Philipsen, S., 2894 Phillips, R.A., 3051 Piatti, S., 1516 Pineau, T., 60 Plasterk, R.H.A., 755 Plug, A.W., 2423 Polyak, K., 1945 Powell, F.L., 1751 Price, C.W., 2265 Pritchard, D.K., 1131 Prives, C., 1054, 2438 Prusiner, S.B., 1736 Ptashne, M., 2359 Pulkkinen, L., 1724 Qiu, W.R., 2251 Quinn, J.C., 435 Ramos, Y.F.M., 816 Ramqvist, T., 2720 Rao, L., 461 Rauscher, F.J., III, 2067 Ray, R.P., 1711 Reed, R., 244 Reese, J.C., 2368 Reichmann, E., 2462 Reinberg, D., 1049, 2657 Rey, R., 2577 Riesgo-Escovar, J.R., 2759 Riethmacher, D., 1184 Riley, D.J., 2794 Rio, D.C., 921 Roberts, J.M., 1979 Roeder, R.G., 2389 Roemer, T., 777 Rohrschneider, L.R., 1084 Romo, A., 196 Rosbash, M., 1699 Rosenfeld, M.G., 1751 Ross, W., 16 Roth, D.B., 553 Roth, S.Y., 1247 Rothman, J.H., 1543 Rouvi~re, P., 3170 Rubin, G.M., 272, 2684 Rudaz, C., 2462 Rudnicki, M.A., 1173 Rugg, E.L., 1724 Rusconi, C.P., 2870 Russell, P., 2276 Ruvkun, G., 1395, 3041 Saavedra, C., 1608 Sabbatini, P., 461 Sadoff, B.U., 2564 Sager, B.M., 2237 Saigo, K., 1645 Samuels, M., 2289 Samuelson, G.C., 2981 Sanchez, Y., 2632 Sawa, H., 2189 Sayers, R., 2981 Scalzo, D., 185 Schatz, D.G., 948 Schedl, P., 3202 Schek, N., 325 Scherer, S.S., 1751 Schier, A.F., 3077 Schleiffer, A., 129


Schlissel, M., 2055 Schneider, R.J., 1557 Schnepp, B., 2302 Schfipbach, T., 1711 Schubiger, G., 1131 Schultz, M.C., 686 Schwarz, H., 2462 Scott, M.P., 301 Segall, J.E., 118 Segil, N., 2389 Seicher, D.W., 2067 Seitz, T., 1455 Serbedzija, G.N., 2452 Shaham, S., 578, 1073 Shao, J., 873 Shapiro, L., 1532 Sharp, P.A., 2079 Sheaff, R.J., 1979 Sheridan, P.L., 37 Sherratt, D., 762 Shieh, J.-C., 2289 Shilo, B.-Z., 93, 2993 Shimura, Y., 997 Shiozaki, K., 2276 Shore, D., 1297 Shvarts, A., 2969 Silver, P.A., 1233 Simanis, V., 2707 Simard, C., 1930 Simcox, A., 2302 Simkovich, N., 2359 Singh, H., 2335 Sisco, P.H., 3018 Skeath, J.B., 3003 Slack, F.J., 740 Sluss, H.K., 2732 Smale, S.T., 873 Smibert, C.A., 2600 Smith, D., 2158 Smith, F.J.D., 1724 Smith, J.R., 804 Smith, M.M., 1247 Snyder, M., 777 S~gaard-Andersen, L., 740 Soares, V.C., 1467 Sohrmann, M., 2707 Solomon, J.M., 2014 Solomon, N.M., 272 Sonnenberg-Riethmacher, E.,

1184

Soriano, P., 1845 Spence, A.M., 2314 Spiegelman, B.M., 974, 1096 Spradling, A.C., 2514 St-Arnaud, R., 1763 Starr, D.B., 1271 Steffan, J.S., 2551 Stepanova, L., 1491 Stephens, C., 1532 Stern, D.F., 395 Stillman, D.J., 604 Storb, U., 2335 Strasser, A., 2055 Stutz, F., 1699 Sun, X., 2881 Sun, Z., 395

Sutherland, J.D., 1411 Suzuki, T., 1783 Symington, L.S., 2025 Symonds, H., 826 Szymanski, P., 3195 Tacke, R., 1569 Takada, S., 313 Takagaki, Y., 2588 Takahashi, F., 1645 Takahashi, T., 528 Takahisa, M., 1783 Takeda, T., 2289 Takeichi, M., 659 Talbot, W.S., 3077 Tan, T.-H., 2251 Tanaka, Y., 528 Tang, H., 16 Taylor, D., 2732 Taylor, E.M., 2423 Tecklenburg, M., 1162 Telling, G.C., 1736 Tempst, P., 1049 Tepass, U., 672 Therrien, M., 272, 1284, 2684 Thiele, D.J., 592, 1917 Thomas, J.R., 1271 Thompson, C.B., 2621 Thorner, J., 2831 Thress, K., 1979 Timchenko, N.A., 804 Tjian, R., 50, 2903 T6r6k, T., 672 Toda, T., 2289 Togashi, S., 1783 Tollervey, D., 502 Tontonoz, P., 974 Toone, W.M., 2289 Torchia, M., 1736 Torres, M., 1443 Tracy, R.B., 1890 Tremblay, J.l., 1284 Tremblay, P., 1736 Trimborn, T., 2894 Tsai, L.-H., 816 Tsai, S., 1084 Tsou, A., 934 Tucker, K.L., 1008 Tung, K.-S., 1608 Ueda, R., 1783 Uemura, T., 659 Uitto, J., 1724 van der Spoel, A., 3156 Van Dyke, T., 245, 826 Varmus, H.E., 836 Vermeulen, W., 1219 Verrijzer, C.P., 873 Vidal, M., 1206 Vincent, J.-P., 3183 Virbasius, C.-M.A., 2368 Virta-Pearlman, V., 3094 Visa, N., 2881 Vogelstein, B., 1945 Volk, T., 2993 Vos, J.C., 755 Voytas, D.F., 634 Vu, L., 887

Wade, M., 245 Wahl, G.M., 934 Waldman, T., 1945 Walter, B., 1184 Walters, M.C., 185 Wang, J., 220 Wang, J., 2588 Wang, K., 2859 Wang, W., 2117 Wang, X., 2251 Wang, X.W., 1219 Wang, Z., 2949 Wang, Z-F., 3028 Ward, J.M., 60 Wassarman, D.A., 272 Wasylyk, B., 2198 Weinberg, R.A., 1633 Weitzman, M.D., 196 Weizman, 1., 93 Wells, S.E., 220 West, J.D., 435 Weston, K., 2732 Wharton, R.P., 1422, 2610 Wheat, W., 2198 White, E., 1,461 Whitfield, M.L., 3028 Wightman, B., 3041 Wijgerde, M., 2894 Wilde, M., 804 Wilder, E., 3116 Wilk, R., 93 Wilkinson, M.G., 2289 Williams, B.O., 1621 Williams, C.J., 2038 Wilson, J.E., 2600 Wolkow, C.A., 2145 Wong, M.H., 985 Wright, R., 1532 Wu, H., 245 Wu, Y., 2359 Wurtz, T., 2881 Xie, J.-E., 1206 Xiong, Y., 245 Xu, G., 1219 Xu, J.-R., 2696 Xu, Y., 2401, 2411 Xuc, D., 1073 Xue, Y., 2117 Yamamoto, K.R., 1271, 2131 Yang, X., 2265 Yao, T.-P., 2478 Yasukawa, T., 528 Yeh, H., 1219 Yeung, K., 1049 Yin, C., 826 Yin, X.-M., 2859 Yokomori, K., 50 Yost, C., 1443 Yotov, W.V., 1763 Younger-Shepherd, S., 421 Yudkin, M.D., 794 Yueh, A., 1557 Zakany, J., 2326 Zachary, K., 3116 Zacksenhaus, E., 3051 Zaret, K.S., 1670

Zeidler, M.P., 50 Zeng, Y., 1835 Zhang, J., 2167 Zhang, S.-D., 1108 Zhao, G.-Q., 1657 Zheng, M., 1670 Zhou, J., 3195 Zhou, S., 2117, 2903 Zhu, C., 553 Zou, S., 634 Zuo, P., 1356 Zweiger, G., 1532


Subject Index, Volume 10 (1996)

ACT3 gene, epigenetic effects on yeast transcription caused by mutations (Jiang and Stillman), 604- 619

Actin, LIM-mediated binding of MLP to cytoskeleton (Arber and Ca- roni), 289-300

Actin-related protein, epigenetic effects on yeast transcription caused by mutations (Jiang and Stillman), 604-619

Activating transcription factor-2 Spcl regulation of S. pombe homolog

Atfl (Shiozaki and Russell), 2276-2288

role of DNA-binding domain as inhib- itory region (Li and Green), 517- 527

Activation, transcriptional by c, CTD-DNA interactions in E. coli

(Gaal et al.), 16-26 CBP as a coactivator of c-Myb (Dai et

al.), 528-540 cell-cycle regulation of SBF binding

(Koch et at.), 129-141 during Drosophila embryogenesis

(Pritchard and Schubiger), 1131-1142

functional TBP epitopes for Pol II activity (Bryant et al.), 2491-2504

inhibition by the ATF-2 DNA-binding domain (Li and Green), 517-527

regulation of transcriptional pausing on nucleosomal templates (Brown et al.), 1479-1490

role of TFIIA-TFIID complex formation in gene activation (Chi and Carey), 2540-2550

specificity of Myc (Desbarats et al.), 447-460

Activators, gene-specific, findings presented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary

Activin, participation of Madr2 in signaling pathway (Baker and Har- land), 1880-1889

Activity, context-dependent, altered intracellular receptor activation (Starr et al.), 1271-1283

ADD1, role in adipocyte differentiation (Kim and Spiegelman), 1096- 1107

Adenine DNA methyltransferases, CcrM as target of Lon protease in C. crescentus (Wright et al.), 1532-1542

Adenovirus POD organization and viral DNA rep-

lication (Doucas et al.), 196- 207

regulation of E2F degradation by trans-

forming proteins (Hateboer et al.), 2960-2970

use of ribosome jumping for translation of late mRNAs (Yueh and Schneider), 1557-1567

Adhesion proteins, role of plx in tracheal function (Zhang et al.l, 1108- 1119

Adipogenesis. See also Differentiation, adipocyte

differential activity of multiple PPAR isoforrns (Brun et al.), 974-984

role of Rb interaction with C/EBPs in adipocyte terminal differentiation (Chen et al.), 2794--2804

Adipose tissue, differential adipogenic activity of multiple PPAR isoforrns (Bran et al.), 974-984

AINTEGUMENTA, similarity of maize Glossyl5 (Moose and Sisco), 3018-3027

Alport syndrome, COL4A3-deficient mice as model (Cosgrove et al.), 2981- 2992

AML1, homologous domains found in Drosophila Lozenge (Daga et al.), 1194-1205

Anaphase, regulation in S. cerevisiae by APC-dependent degradation of Pdslp (Cohen-Fix et al.), 3081- 3093

Anaphase-promoting complex, role in Pdslp degradation in {Cohen- Fix et al.), 3081-3093

Anchoring site, binding by U2 snRNP proteins (Gozani et al.), 233-243

Anti-cancer agents, p53-dependent cell cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947

Anticodon, as signal sequence for tRNA import into mitochondria (Rusconi and Cech), 2870-2880

Antimetabolites, induction of p53-dependent cell-cycle arrest by ribonucleotide depletion (Linke et al.), 934-947

Antisigma factor, interaction of SpoIIAB with cr in B. subtilis (Decatur and Losick), 2348-2358

APC. See Anaphase-promoting complex APETALA2, similarity of maize Glossyl 5

(Moose and Sisco), 3018-3027 APETALA3, nuclear colocalization with

PISTILLATA (McGonigle et al.), 1812-1821

Apoptosis. See also Programmed cell death

Bcl-x L and p53 in mitotic checkpoint control (Minn et al.), 2621-2631


effects of wild-type p53 transgene ex-

pression (Godley et al.), 836- 850


genetic determinants of p53 induction (Polyak et al.), 1945-1952; Erra- tum, 2818

induction by ectopic E2F expression in Drosophila (Asano et al.), 1422- 1432



p53 levels and extent of tumor cell response (Chen et al.), 2438-2451

in plO7-null mice (Lee et al.), 1621- 1632

in Rb +/- mice (Nikitin and Lee), 1870-1879

regulation of skeletal muscle cell proliferation by Rb (Zackenhaus et al.}, 3051-3064


rise and fall during multistage tumorigenesis (Naik et al.), 2105-2116

role of grim in Drosophila (Chen et al.),

1773-1782 p53 (Ko and Prives), 1054--1072 Re-

view TrkB and TrkC in promoting neuron

survival (Minichello and Klein), 2849-2858

XPB and XPD in p53-dependent pathway (Wang et al.), 1219- 1232



tissue-specific inactivation of p53 tumor suppression in mice (Bow- man et al.1, 826--835

up-regulation by dominant interfering Myb (Taylor et al.), 2732-2744

Appressorium, formation during rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706

Arabidopsis, nuclear colocalization of APETALA3 and PISTILLATA (McGonigle et al.), 1812-1821

araucan, positive regulation of by Dpp and Ci during wing patterning (G6mez-Skarmeta and Mod- olell), 2935-2945

Arches, branchial, role of pescadillo development in zebrafish (Allende et al.), 3141-3155

ASF. See ASF/SF2


ASF/SF2, role in activation of polyadenylation by in-

tron enhancer (Lou et al.), 208- 219

cell viability (Wang et al.), 2588-2599 in splicing (Manley and Tacke), 1569-

1579 Review Asymmetric cell division. See Cell divi-

sion, asymmetric Asymmetry, coupling of cell lineage

asymmetry with transcription of unc-86 (Baumeister et al.), 1395-1410

Ataxia telangiectasia. See ATM Atf-1, regulation by Spcl in S. pombe

(Shiozaki and Russell), 2276- 2288

ATF2. See Activating transcription factor-2

ATM association with meiotically pairing

chromosomes (Keegan et al.), 2423-2437

effects of gene inactivation in mice (Xu et al.), 2411-2422

role in cell-cycle regulation (Xu and Balti-

more), 2401-2410 different cell types and functional

links to p53 (Hawley and Friend), 2383-2388 Review

Atr, association with meiotically pairing chromosomes (Keegan et al.), 2423-2437

Attenuator, Fab-7 as boundary element in Drosophila

(Zhou et al.), 3195-3201 as chromatin domain boundary in


Axial growth, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777-793

Axis formation, role of [3-catenin and Xgsk-3 in Xenopus (Yost et al.), 1443-1454

AXL2, role in axial growth site selection in yeast (Roemer et al.), 777- 793

B

B cells Pax-5 recruitment of Ets proteins to

mb-1 promoter (Fitzsimmons et al.), 2198-2211

proteins, sequence-specific DNA binding of POU domain coactivator OCA-B (Cepek et al.), 2079- 2088

role of p300/CBP and bHLH proteins in differentiation (Eckner et al.), 2478-2490

Bacillus subtilis

bifunctionality of SpoIIE in asymmetric cell division and cell-specific transcription (Feucht et al.), 794-803

bipolar localization of FtsZ (Levin and Losick), 478-488

interaction of SpoIIAB with (r F (Deca- tur and Losick), 2348-2358

role of extracellular peptide in different development pathways (So- lomon et al.), 2014-2024

signaling by serine kinases and phosphatases in response to stress (Yang et al.), 2265-2275

BAFs. See BRGl-associated factors bagpipe, role in segmentation and speci-

fication of Drosophila mesoderm (Azpiazu et al.), 3183- 3194

Bar, positive regulation by Drosophila Lozenge (Daga et al.), 1194- 1205

Base pairing, of U2 and U6 snRNAs during splicing (Field and Friesen), 489-501

Basement membrane, effects of collagen COL4A3 gene inactivation in mice (Cosgrove et al.), 2981- 2992

basket, as encoding Drosophila JNK (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.1, 2759- 2768

Bax interaction with E1B 19K (Han et al.),

461-477 up-regulation by p53 (Ko and Prives),

1054-1072 Review Bcl-2 family

functional interaction of E1B 19K with Bax (Han et al.I, 461--477

role in apoptosis (White), 1-15 Review cell-death activities in developing C.


BcI-x L BID as novel death agonist possessing

only a BH3 domain (Wang et al.), 2859-2869

regulation of apoptosis during multistage tumori-

genesis [Naik et al.), 2105-2116 bcl-2 by dominant interfering Myb

(Taylor et al.), 2732-2744 role in mitotic checkpoint control

(Minn et al.), 2621-2631 up-regulation of bcl-2 by E26 v-Myb

(Frampton et al.), 2720-2731 Belousov-Zhabotinsky reaction, propa-

gation of traveling waves (Sager), 2237-2250 Review

~-Catenin perturbation of distribution by forced

expression of E-cadherin (Her- miston et al.I, 985-996

regulation by Xgsk-3 (Yost et al.), 1443-1454

role in signal transduction during embryogenesis (Miller and Moon), 2527-2539 Review

B-Globin, role of EKLF in human gene competition (Wijgerde et al.), 2894-2902

[3-Globin 5'HS2 enhancer, in the study of position-effect variegation (Wai- ters et al.), 185-195

BH3 domain, in novel death agonist BID (Wang et al.), 2859-2869

bHLH proteins. See Helix-loop-helix proteins, basic

bicoid, novel related homeo box factor Ptxl (Lamonerie et al.), 1284- 1295

BID, novel death agonist possessing only a BH3 domain (Wang et al.), 2859-2869

Bithorax complex, Fab-7 attenuation of enhancer-promoter in-



BMP-4, activation of Lefl expression (Kratochwil et al.), 1382-1394

Bmp4, regulation by zebrafish dino and swirl (Hammerschmidt et al.), 2452-2461

BMPs. See Bone morphogenetic proteins Bone morphogenetic proteins

regulation of Bmp4 by dino and swirl in zebrafish (Hammerschmidt et al.), 2452-2461

role in embryonic development (Hogan), 1580-1594 Review

role of Bmp8b in spermatogenesis and fertility in mice (Zhao et al.L 1657-1669

Boundary elements, Fab-7 attenuation of enhancer-promoter in-



Branchial arches. See Arches, branchial Branchpoint sequences, binding up-

stream by U2 snRNP proteins and spliceosome assembly (Goz- ani et al.), 233-243

Brcal, effects of gene inactivation in mice (Liu et al.), 1835-1843

Breathless, role in patterning cell migration and branching in Droso- phila (Lee et al.), 2912-2921

BRGl-associated factors, similarity to yeast SWI/SNF factors (Wang et al.), 2117-2130

BSAP, recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211


Bud site inhibition of ATF-2 activation by its

DNA-binding domain (Li and Green), 517-527

role of Axl2p in selection (Roemer et al.), 777-793

bZIP protein. See Leucine zipper protein, basic

C

C-factor. See C-signaling C-signaling

branched pathway in Myxococcus (Sogaard-Andersen et al.), 740- 754

traveling wave propagation in Myxo- coccus morphogenesis (Sager), 2237-2250 Review

c-Jun amino-terminal kinases activation by HPK1 (Hu et al.), 2251-

2264 Drosophila pathway mediating mor-

phogenesis and an immune response (Sluss et al.), 2745-2758


c-Myb, role of EVES motif in regulation (Dash et al.), 1858-1869

c-myc collaboration with Notch l for onco-

genesis (Girard et al.), 1930- 1944

specificity in gene activation by Myc (Desbarats et al.), 447-460

c-ros, role of in epithelial development (Sonnenberg-Riethmacher et al.), 1184-1193

C-SrC

effects of gene disruptions in mice (Lowell and Soriano), 1845- 1857 Review

regulation of eye development by related Drosophila gene Dsrc41 (Takahashi et al.), 1645-1656

C/EBPs. See CCAAT/enhancer-binding proteins

Cadherins colocalization of Drosophila Dsrc41

and DE-cadherin in developing eyes (Takahashi et al.), 1645- 1656

role in intestinal epithelial cell migration (Hermiston et al.), 985-996

Caenorhabditis elegans coupling of cell lineage asymmetry


in vitro transposition of Tel (Vos et al.), 755-761



role of FEM-2 in sex determination (Chin-

Sang and Spence), 2314-2325 lin-14 3' UTR in down-regulation of

translation (Ha et al.), 3041- 3050

lin-17 in asymmetric cell division in (Sawa et al.), 2189-2197

sere-4 in neuronal and mesodermal development (Basson and Hor- vitz), 1953-1965

SL1 trans-spliced leader RNA in embryogenesis (Ferguson et al.), 1543-1556


Calcitonin alternative splicing of pre-mRNA (Lou

et al.), 208-219 gene-related peptide, generation

through alternative splicing of calcitonin pre-mRNA (Lou et al.), 208-219

cAMP. See Cyclic AMP Cancer. See also Carcinogenesis; Onco-

genesis; Specific oncogenes; Tu- morigenesis

ATM as susceptibility gene (Hawley and Friend), 2383-2388 Re- view

breast, effects of Brcal gene inactivation in mice (Liu et al.), 1835- 1843

p53-dependent cell cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947

rearrangement of Notchl in mouse thymomas in MMTV/myc transgenic mice (Girard et al.}, 1930-1944



Cap-binding complex, nuclear Mudl3p as yeast homolog of CBP20

(Colot et al.), 1699-1708 role in pre-mRNA recognition and

splicing (Lewis et al.), 1683- 1698

Cap-binding protein, requirement for ribosome jumping in virus-infected and heat-shocked cells (Yueh and Schneider), 1557- 1567

Cap-prevented recombination. See Re- combination, cap-prevented

Carboxy-terminal domain, role in Pol II transcription (Orphanides et aL), 2657-2683 Review

Carcinogenesis, neuroendocrine role of Rb (Nikitin and Lee), 1870-1879

Caulobacter crescentus, role of Lon protease in cell-cycle control of DNA methylation (Wright et al.), 1532-1542

caupolican, positive regulation of by Dpp and Ci during wing patterning (G6mez-Skarmeta and Modolell), 2935-2945

CBC. See Cap-binding complex, nuclear CBP. See CREB-binding protein CBP20, identification of yeast homolog

Mudl3p (Colot et al.), 1699- 1708

CCAAT/enhancer-binding proteins, role of

C/EBP-c~ in elevation of p21 (Tim- chenko et al.), 804--815

interaction with Rb in adipocyte terminal differentiation (Chen et al.), 2794-2804

CcrM, as target of Lon protease in Caw lobacter (Wright et al.), 1532- 1542

CD40, role of TANK in CD40L-mediated NF-KB activation (Cheng and Baltimore), 963-973

Cdc2 kinase, inhibition by Rum1 (Jalle- palli and Kelly), 541-552

Cdc2/cyclin B complexes, regulation by Xenopus Sucl homolog Xe-p9 (Patra and Dunphy), 1503-151

Cdc6, role in promoting replication during the cell

cylce (Piatti et al), 1516-1531 regulation of eukaryotic DNA replica-

tion (Diffley), 2819-2830 Review Cdc7, role in regulation of eukaryotic

DNA replication (Diffley), 2819-2830 Review

Cdcl0, AXL2 as high copy suppressor in spa2~ cdcl0-10 mutant strains (Roemer et al.), 777-793

Cdc 18, interaction with Rum 1 (Jallepalli and Kelly), 541-552

Cdc25, degradation of maternal mRNAs in maternal/zygotic transition (Edgar and Datar), 1966-1977

Cdc28p, role in regulation of eukaryotic DNA replication (Diffley), 2819-2830 Review

CDC37, encoding of protein kinase-targeting subunit of Hsp90 by mammalian homolog (Stepa- nova et al.), 1491-1502

CDC55, as encoding the regulatory subunit of ceramide-activated protein phosphatase in S. cerevisiae (Nickels and Broach), 382- 394

CDK inhibitors. See Cyclin-dependent kinase inhibitors

cdk2 regulation of cyclin E turnover by the

ubiquitin pathway (Clurman et al.), 1979-1990

role in control of pRB and E2F function


during GI exit (Hofmann and Livingston), 851-861

cdk3, dominant-negative inhibition of E2F-1 in Rb-independent man- ner (Hofmann and Livingston), 851-861

cdk5, regulation of neurite outgrowth (Nikolic et al.), 816-825

CDKs. See Cyclin-dependent kinases CED-3, substrate specificities of ICE-like

proteases (Xue et al.), 1073--1083 ced-3, role in cell-death activities in de-

veloping C. elegans neurons (Shaham and Horvitz), 578-591

cecl-4, role in cell-death activities in developing C. elegans neurons (Shaham and Horvitz), 578-591

cecl-9, role in cell-death activities in developing C. elegans neurons (Shaham and Horvitz), 578-591

Cell adhesion, role of cadherins in intesti-

nal epithelium (Hermiston et al.1, 985-996

cycle arrest from p21 overexpression in

transgenic mice (Wu et al.), 245-260

arrest induced by ribonucleotide depletion (Linke et al.), 934-947

Bcl-x L and p53 in mitotic checkpoint control (Minn et al.), 2621-2631


cdk2 and cdk3 action in G 1 IHof- mann and Livingston), 851-861

ceramide-activated protein phosphatase mediates ceramidedn- duced G L arrest in Saccharomy- ces cerevisiae (Nickels and Broach), 382-394

coincident regulation with clonality during T-cell receptor development (Hoffman et al.I, 948-962

cyclin E requirement for E2F-induced S phase (Duronio et al.), 2505-2513

determinants of late origin activation in yeast (Friedman et al.), 1595-1607

induction of S phase by ectopic E2F expression in Drosophila (Asano et al.), 1422-1432

influence of p53 levels on arrest (Chen et al.), 2438-2451

modulators of histone function in yeast (Ma et al.), 1327-1340

p53-dependent arrest induced by ribonucleotide depletion (Linke et al.), 934-947


protection of E2F-1 from ubiquitin-

proteasome degradation pathway by Rb (Hofmann et al.), 2949-2959

regulation by ATM (Xu and Baltimore),

2401-2410 of E2F degradation by Rb family

proteins and adenovirus transforming proteins (Hateboer et al.), 2960--2970

of S-phase onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654

of SBF binding (Koch et al.), 129- 141

of skeletal muscle cell proliferation by Rb (Zackenhaus et al.), 3051-3064

by Xenopus Sucl homolog Xe-p9 (Patra and Dunphy), 1503-151

requirement for yeast TAFn90 (Apone et al.), 2368-2380

role of Lon protease in control of DNA

methylation (Wright et al.), 1532-1542

p21 in keratinocyte growth and differentiation (Missero et al.), 3065-3075

p53 (Ko and Prives), 1054-1072 Review

rapamycin-sensitive TOR function in yeast (Alarcon et al.), 279-288

Rb interaction with C/EBPs in adipocyte terminal differentiation (Chen et al.), 2794-2804

Rum 1 inhibition of Cdc2 kinase and interaction with Cdcl8 (Jalle- palli and Kelly), 541-552

termination of early program in Drosophila embryogenesis (Ed- gar and Datar), 1966-1977

timing of replication promotion by Cdc6 (Piatti et al.), 1516-1531

truncation of S phase during the Drosophila endocycle (Lilly and Spradling), 251 4-2526

division asymmetric

coupling of cell lineage asymmetry with unc-86 transcription (Baumeister et al.), 1395-1410

role of lin-17 in C. elegans (Sawa et al.), 2189-2197

role of SpoIIE in Bacillus subtilis (Feucht et al.), 794-803

bipolar localization of FtsZ in Bacil- lus subtilis (Levin and Losick), 478-488

fate cadherins role in intestinal epitheli-

al cell migration (Hermiston et al.), 985-996

signal transduction role through ~-catenin during embryogenesis

(Miller and Moon), 2527-2539 Review

growth defects in ATM-deficient mice (Xu

et al.), 2411-2422 interactions, regulation by Dsrc41

in developing Drosophila eyes (Takahashi et al.I, 1645-1656

invasion, regulation of tumor cell plasticity by TGF-~ and Ha-Ras (Oft et al.), 2462-2477

regulation by ATM IXu and Balti- more), 2401-2410

migration Breathless role in the Drosophila

tracheal system (Lee et al.), 2912-2921

C-signaling role and traveling wave propagation in Myxococcus (Sager), 2237-2250 Review

cadherins role in intestinal epithelium (Hermiston et al.), 985-996

cAMP role and traveling wave propagation in Dictyostelium (Sager), 2237-2250 Review

Heartless role in Drosophila development (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017

polarity, regulation by lin-17 in C. e/- egans (Sawa et al.), 2189-2197

rearrangement, epithelial E-cadherin role in Drosophila (Ue-

mura et al.), 659-671; (Tepass et al.), 672-685

signaling during Drosophila oogenesis (Ray

and Sch~ipbach), 1711-1723 Re- view

in hepatic specification of gut endoderm (Gualdi et al.), 1670--1682

role of extracellular peptide in different development pathways in B. subtilis (Solomon et al.), 2014-- 2024

specificity conversion of aNAC to myotube-



role of novel bicoid-related homeo box factor Ptxl (Lamonerie et al.), 1284-1295

sequence-specific DNA binding of B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2088


Central nervous system. See Nervous system, central

Geramide-activated protein phos-


phatase. See Protein phosphatase, ceramide-activated

Cerebellum, role of TrkB and TrkC in promoting granule neuron survival (Minichello and Klein), 2849-2858

CF. See Core factor CF2, role in EGF-R-activated dorsoven-


Chaperone proteins, p50 Cdr as protein kinase-targeting subunit of Hsp90 (Stepanova et al.), 1491- 1502

Checkpoints activation by V(D)J recombination in

scid mice (Guidos et al.), 2038- 2054

Bcl-x L and p53 in control (Minn et al.), 2621-2631


cyclin E role in truncation of S phase during the Drosophila endocycle {Lilly and Spradling), 2514- 2526


regulation of S-phase onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654

Spkl/Rad53 regulation by Mecl-dependent protein phosphorylation (Sun et al.), 395-406

topoisomerases role in chromosome condensation in S. cerevisiae (Castaho et al.), 2564-2576

• preferred selection by RecA protein (Tracy and Kowalczykowski), 1890-1903

Cholesterol metabolism, mediation of SREBP transcriptional activity by CBP (Oliner et al.), 2903- 2911

Chromatin activator-dependent regulation of tran-

scriptional pausing on nucleosomal templates {Brown et al.), 1479-1490



identification of mammal ian SWI/ SNF complexes (Wang et al.), 2117-2130

in transcriptional activation and repression {Kingston et al.), 905- 920 Review

interaction of Tupl wi th histones H3 and H4 (Edmondson et al.), 1247-1259

NF-KB p50 role in nucleosome arrange- ment of HIV-1 enhancer (Pazin et al.), 37-49

role in hepatic specification of gut endoderm (Gualdi et al.), 1670- 1682

silent, preferential integration of Ty5 (Zou et al.), 634-645

Chromosome association of Atr and Atm with mei-

otic pairs (Keegan et al.), 2423- 2437

condensation, role of topoisomerases in S. cerevisiae (Castaho et al.), 2564-2576

fragmentation in A TM-deficient mice (Xu et al.), 2411-2422

localization of TFIID and inhibition of activator-dependent transcription (Segil et al.), 2389-2400

organization dif resolvase site insertions in E. coli

(Kuempel ct al.), 1162-1171; Corrigendum, 1709

:restriction of dif site activity in E. coli (Cornet et al.), 1152-1161

walk, to identify determinants con- trolling activation of yeast replication origins (Friedman et al.), 1595-1607

ci. See cubitus interruptus CIF, role in TFIID-dependent initiator

function (Kaufmann et al.), 873- 886

CIP-1. See p21 CKIs. See Cyclin-dependent kinase in-

hibitors ClbS. See Cyclins Clb6. See Cyclins Cleavage-polyadenylation specificity

factor, interaction with U1 snRNP (Lutz et al.), 325-337

Clnl . See Cyclins Cln2. See Cyclins Cln3. See Cyclins CNS. See Nervous system, central Coactivators, transcriptional


interaction of CBP with (Dai et al.), 528-540


role of TFIIA in Ras-mediated photoreceptor determination (Zeidler et al.), 50-59

sequence-specific DNA binding of B-cell POU domain coactiva- tot OCA-B (Cepek et al.), 2079- 2088

Coconvcrsion, biases accompanying intron homing (Mueller et al.), 2158-2166

Cofactors

role of EVES motif in c-Myb regulation (Dash et al.), 1858-1869

transcriptional findings presented at Cold Spring

Harbor meeting (McKnight), 367-381 Meeting commentary

role of CIF in TFIID-dependent initiator function (Kaufmann et al.), 873-886

COL4A3, effects of gene inactivation in mice {Cosgrove et al.), 2981-2992

Collagen, effects of COL4A3 gene inac- t ivation in mice (Cosgrove et al.), 2981-2992

Competence and sporulation stimulating factor, role of extracellular peptide in different development pathways in B. subtilis {Solomon et al.), 2014-2024

Competence, genetic, role of extracellular peptide in B. subtil is (So- lomon et al.), 2014-2024

Conjugation Atfl regulation by

Spcl in S. pombe (Shiozaki and Rus- sell), 2276-2288

Styl in S. p o m b e {Wilkinson et al.), 2289-2301

conjugating plasmids as preferred targets for Tn7 (Wolkow et al.), 2145-2157

Copper transport, role of yeast protein Ctr3 (Knight et al.), 1917-1929

Core factor, requirement for TBP in UAF-dependent recruitment (Steffan et al.), 2551-2563

Corepressors, role of KAP-1 for KRAB domain {Friedman et al.), 2067- 2078

Corkscrew, analysis of interaction with Torso (Cleghon et al.), 566-577

Corrigenda Gertler et al., 2234 Kuempel et al., 1709

CPP32, similari ty CED-3 substrate specificity (Xue et al.), 1073-1083

CPR. See Recombination, cap-prevented CPSF. See Cleavage-polyadenylation

specificity factor CREB-binding protein

as a coactivator of c-Myb (Dai et al.), 528-540

role in cell differentiation (Eckner et al.),

2478-2490 mediation of SREBP transcriptional

activity (Oliner et al.), 2903- 2911

Crk, phosphorylation of Sin (Alexandro- poulos and Baltimore), 1341- 1355

Crypt-villus, role of cadherins in intestinal epithelial cell migration (Hermiston et al.), 985-996

CSF. See Competence and sporulation st imulat ing factor


csgA branched C-factor signaling pathway

in Myxococcus (Sogaard-Ander- sen et al.), 740-754

C-signaling and traveling wave propagation in Myxococcus {Sager), 2237-2250 Review

CTD. See RNA polymerase, carboxy-terminal domain

CTR3, role of protein product in copper transport in yeast (Knight et al.), 1917-1929

cubitus interruptus activation of patched in response

Hedgehog signaling {Alexandre et al.), 2003-2013

positive regulation of araucan and caupolican (G6mez-Skarmeta and Modolell), 2935-2945

CUS1, role of gene product in spliceosome assembly {Wells et al.), 220-232

Cyclic AMP regulation of rice blast fungus M.

grisea infection (Xu and Hamer), 2696-2706

traveling wave propagation in Dictyo- stelium (Sager), 2237-2250 Re- view

Cyclin-dependent kinase inhibitors effect of p21 overexpression in trans-

genic mice (Wu et al.), 245-260 role of p21 in keratinocyte growth and

differentiation (Missero et al.), 3065-3075

Ruml inhibition of Cdc2 kinase and interaction with Cdcl8 (Jalle- palli and Kelly), 541-552

vitamin D 3 induction of p21 (Liu et al.), 142-153

Cyclin-dependent kinases activation by Cdc6 during the cell

cylce {Piatti et al.), 1516-1531 cdk2 and cdk3 action in G l (Hofmann

and Livingston), 851-861 Cdk4 as target of Cdc37 in mouse fi-

broblasts (Stepanova et al.), 1491-1502

cell-cycle regulation of SBF binding (Koch et al.), 129-141


role of Xenopus Sucl homolog Xe-p9 in cell cycle control (Patra and Dunphy), 1503-1515

Cyclins cdk-dependent cyclin E ubiquitination

{Clurman et al.), 1979-1990 cell-cycle regulation through SBF

{Koch et al.), 129-141 Clb/Cdc28 in displacing SBF from pro-

moters during G2 (Koch et al.), 129-141

cyclin E requirement for E2F-induced

S phase (Duronio et al.), 2505- 2513

effect of p21 overexpression on cyclin- CDK complex activity (Wu et al.), 245-260

p53-dependent induction of cyclin G (Ko and Prives), 1054-1072 Re- view

role of cyclin E in S phase during the Drosophila endocycle (Lilly and Spradling), 2514-2526

Cyclins, D-type, coexpression of Cdc37 with cyclin D1 in proliferating cells (8tepanova et al.), 1491- 1502

Cysteine proteases role in




Cytokinesis, role of dmfl /midl in positioning of division septum in fission yeast {Sohrmann et al.), 2707-2719

Cytoskeleton, role of plectin in membrane adherence (McLean et al.), 1724-1735

Danio rerio prospects for insertional mutagenesis

(Schier et al.), 3077-3080 Mini- review

role of pescadillo and dead eye in embryonic development (Allende et al.), 3141-3155

dead eye, role in zebrafish development (Allende et al.), 3141-3155

Decapentaplegic positive regulation of araucan and

caupolican {G6mez-Skarmeta and Modolell), 2935-2945

prevention of autoactivation by sog (Biehs et al.}, 2922-2934

decapentaplegic, activation by Cubitus interruptus (Alexandre et al.), 2003-2013

Delta, in Drosophila wing development (Doherty et al.), 421-434

Dentate gyms, role of TrkB and TrkC in promoting neuron survival (Minichello and Klein), 2849- 2858

Development, general cloning of a novel human kinase gene

with homology to Drosophila female sterile homeotic (Denis and Green), 261-271

effects of in vivo mutagenesis of re-

quired HoxD complex regulatory element (G6rard et al.), 2326-2334



role of Heartless in Drosophila cell migra-

tion and mesodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017

lin-14 3' UTR temporal gradient formation in C. elegans (Ha et al.), 3041-3050

pescadillo and dead eye in zebrafish embryogenesis (Allende et al.), 3141-3155

p53 (Ko and Prives), 1054-1072 Re- view

Development, specific. See also Specific organisms

axial, mouse Wnt-3a gene dosage regulation (Greco et al.), 313-324

bone, role of Src-family kinases (Low- ell and Soriano), 1845-1857 Re- view

cartilage, role of p107 and p130 in mice (Cobrinik et al.), 1633- 1644

embryonic requirement for Hlx during mouse

visceral organogenesis (Hentsch et al.), 70-79

role of BMPs {Hogan), 1580-1594 Review

epithelial, role of c-ros (Sonnenberg- Riethmacher et al.), 1184-1193

eye effects on photoreceptor specifica-

tion through regulation of Lozenge role in Drosophila (Daga et

al.), 1194-1205 mouse Pax6 role (Quinn et al.), 435-

446 Rasl regulation of prospero tran-

scription in Drosophila (Kauff- mann et al.), 2167-2178

regulation by Dsrc41 in Drosophila (Takahashi et al.), 1645-1656

TFIIA role in Ras-mediated photoreceptor determination (Zeidler et al.), 50-59

hair, regulation of inductive tissue interactions by Lefl expression (Kratochwil et al.), 1382-1394

immune system, coincident regulation of cell cycle and clonality during T-cell receptor development (Hoffman et al.), 948-962

kidney abnormalities in wild-type p53



regulation by Winged Helix protein BF-2 (Hatini et al.), 1467-1478


leaf, role of GlossyI5 in maize {Moose and Sisco), 3018-3027

liver, effect of p21 overexpression in transgenic mice (Wu et al.), 245-260

lymphoid, role of Src-family kinases {Lowell and Soriano), 1845- 1857 Review

male, role of FEM-2 phosphatase in C. elegans (Chin-Sang and Spence), 2314-2325

mesodermal, role of C. elegans sere-4 IBasson and Horvitzl, 1953- 1965

nasal, role of mouse Pax6 (Quinn et al.), 435-446

neural opposing cell-death activities in C.


regulation of neurite outgrowth by cdkS/p35 kinase (Nikolic et al.), 816-825

role of BMPs (Hogan), 1580-1594 Review Src-family kinases {Lowell and So-

riano), 1845-1857 Review neuronal

role of C. elegans sere-4 (Basson and Horvitz), 1953-1965

role of TrkB and TrkC in promoting neuron survival IMinichello and Klein), 2849-2858

postimplantation, abnormalities in BrcaZ-null mice (Liu et al.), 1835-1843


skeletal, role of BMPs {Hogan), 1580- 1594 Review

T-cell, cooperativity of p53 and SCID in lymphomagenesis (Nacht et al.), 2055-2066

tail bud, role of mouse Wnt-3a (Greco et al.), 313-324

tooth regulation of inductive tissue inter-

actions by Lefl expression (Kra- tochwil et al.), 1382-1394


tracheal, role of Breathless in patterning cell migration and branching in Drosophila (Lee et al.), 2912-2921

vertebrate, induction of patched by hedgehog in mice (Goodrich et al.), 301-312

wing regulation of araucan and caupoli-

can during Drosophila pattern

formation (G6mez-Skarmeta and Modolell), 2935-2945

role of Delta in Drosophila (Doherty et al.), 421-434

Dictyostelium discoideum role of cAMP and traveling wave prop-

agation in morphogenesis (Sager), 2237-2250 Review

signal transduction regulation by ERK2 (Gaskins et al.), 118-128

dif, in Xer site-specific recombination (Blakely and Sherratt), 762-773

dif site restriction of activity in E. coli {Cornet

et al.), 1152-1161 resolvase site insertions in E. coli

(Kuempel et al.), 1162-1171; Corrigendum, 1709

Differentiation adipocyte

role of ADD1/SREBP1 (Kim and Spiegelman), 1096-1107

role of Rb interaction with C/EBPs (Chen et al.), 2794-2804

B-cell, role of p300/CBP and bHLH proteins (Eckner et al.), 2478- 2490

cellular, effects of wild-type p53 transgene expression (Godley et al.), 836-850

central nervous system, role of single factors in stem cell differentiation (Johe et al.), 3129-3140

differential adipogenic activity of multiple PPAR isoforms (Brunet al.), 974-984

effects of erythropoietin receptor gene inactivation on primitive and definitive erythropoicsis {Lin et al.), 154-164

epithelial regulation by nude locus product

Whn (Brissette-et al.), 2212- 2221

role of c-ros (Sonnenberg-Riethma- cher et al.), 1184-1193

keratinocyte, role of Src-family kinases (Lowell and Soriano), 1845-1857 Review

muscle, role of p300/CBP and bHLH proteins (Eckner et al.), 2478- 2490

of myelomonocytes induced by vitamin D 3 (Liu et al.), 142-153

myoblast, role of NAC proteins (Yotov and St-Arnaud), 1763-1772

neuronal regulation of neurite outgrowth by

cdk5/p35 kinase (Nikolic et al.), 816-825

role of Lozenge in Drosophila (Daga et al.), 1194-1205

prokaryotic, branched signaling pathway in Myxococcus {Sogaard- Andersen et al.), 740-754

role of cadherins in intestinal epithe-

lium (Hermiston et al.), 985- 996

role of p53 (Ko and Prives), 1054-1072 Review

sexual, role of MIS in mammalians (Mishina et al.), 2577-2587

skeletal muscle, regulation by Rb (Zackenhaus et al.), 3051- 3064

thymocytes, p53 rescue of V(D)J rearrangement in scid mice (Bogue et al.), 553-565

DIG1 and DIG2, novel MAP kinase targets in S. cerevisiae (Cook et al.), 2831-2848

dino, role in zebrafish development {Hammerschmidt et al.}, 2452- 2461

dmfl/midl , role in positioning of division septum in fission yeast {Sohr- mann et al.), 2707-2719

DNA bending, role in transcriptional stimu-

lation by NHP6A/B (Paull et al.), 2769-2781

binding cooperativity of the Oct-1 POU sub-

domains {Klemm and Pabo), 27- 36

sequence specificity of B-cell coactivator OCA-B (Cepek et al.), 2079-2088

-binding domains activation of patched by Cubitus in-


altered intracellular receptor activation (Starr et al.), 1271-1283

inhibition of ATF-2 transcriptional activation (Li and Green), 517- 527

breaks, double-stranded, activation of DNA damage checkpoint by V(D)I recombination (Guidos et al.), 2038-2054

damage in ATM-deficient mice {Xu et al.),

2411-2422 p53 levels and extent of tumor cell

apoptotic response (Chen et al.), 2438-2451

parallel sensory branches for signaling in S. cerevisiae (Navas et al.), 2632-2643

role of p53 in radiation-induced differentiation in scid mice (Bogue et al.), 553-565

and Spkl/Rad53 regulation by Mecl-dependent protein phosphorylation (Sun et al.), 395-406

helicases, role of XPB and XPD in p53- dependent apoptosis (Wang et al.), 1219-1232

methylation, role


in activation of Xist (Panning and Jaenisch), 1991-2002

in establishing genomic imprinting (Tucker et al.), 1008-1020

of Lon protease in Caulobacter (Wright et al.), 1532-1542

methyltransferase, activity during oogenesis and spermatogenesis (Tucker et al.), 1008-1020

polymerase ~, parallel sensory branches for signaling in S. cerevisiae {Navas et al.), 2632- 2643

protein kinase activation of DNA damage check-

point by V(D)J recombination in scid mice (Guidos et al.), 2038- 2054


repair bypass of scid defect by induction of

p53 DNA damage response pathways (Bogue et al.), 553- 565

effects of ATM gene inactivation (Xu and Baltimore), 2401- 2410

encoding of Ku p70 homolog IRBP by Drosophila mus309 (Beall and Rio), 921-933

p53 role (Ko and Prives), 1054-1072 Review

XPB and XPD roles in p53-dependent apoptosis (Wang et al.), 1219-1232

replication parallel sensory branches for DNA

damage signaling in S. cerevisiae (Navas et al.), 2632-2643

promotion by Cdc6 during the cell cycle (Piatti et al.), 1516-1531


regulation and specification of eukaryotic origins (Diffley), 2819- 2830 Review

Spk 1 / Rad53 regulation by Mec 1-dependent protein phosphorylation (Sun et al.), 395406

ribosomal, role of TBP in expression in S. cerevisiae (Steffan et al.), 2551-2563

topoisomerases, role in mitotic chromosome condensation in S. cerevisiae (Castafio et al.), 2564- 2576

DNA-PK. See DNA protein kinase Domains, chromosomal, determinants

of late origin activation in yeast (Friedman et al.), 1595-1607

Dominant-negative mutants cdk2 and cdk3 cell cycle function

(Hofmann and Livingston), 851- 861


role of ADD1/SREBP1 in adipocyte differentiation (Kim and 8piegelman), 1096--1107

Dorsal, activation by Toll, tube, and pelle (Norris and Manley), 862-872

Dorsal closure, mediation by Drosophila JNK pathway (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759-2768

Dorsal-ventral axis, prevention of Dpp autoactivation by Drosophila sog (Biehs et al.), 2922-2934

Double-strand break repair, role in intron mobility (Mueller et al.), 351-364

doublesex, assembly of specific SR protein complexes at the splicing enhancer (Lynch and Maniatis), 2089-2101

Drl, corepressor requirement (Mermel- stein et al.), 1033-1048

Drl-associated polypeptide 1, requirement for Drl-mediated repression (Mermelstein et al.), 1033- 1048

DRAP1. See Drl-associated polypeptide 1

Drosophila activation of dorsal by Toll, tube, and


assembly of specific SR protein complexes at the doublesex splicing enhancer (Lynch and Maniatis), 2089-2101

binding of TFIID to downstream basal promoter element (Burke and Kadonaga), 711-724

cloning of a novel human kinase gene with homology to female sterile homeotic (Denis and Green), 261-271


cyclin E requirement for E2F-induced S phase (Duronio et al.), 2505- 2513

degradation of maternal mRNAs in maternal/zygotic transition (Edgar and Datar), 1966-1977

E-cadherin in epithelial cell rearrangement (Uemura et al.), 659-671; (Tepass et al.), 672-685

encoding of bHLH-PAS protein by trachealess

(Wilk et al.), 93-102 Ku p70 homolog IRBP by DNA re-

pair mutant mus309 (Beall and Rio), 921-933

Fab-7 attenuation of enhancer-promoter interactions in (Zhou et

al.), 3195-3201 gradual activation of transcription dur-

ing embryogenesis (Pritchard and Schubiger), 1131-1142

independent regulation of neighboring genes (Merli et al.), 1260-1270

induction of S phase and apoptosis by ectopic E2F expression in Drosophila (Asano et al.), 1422- 1432

intercellular signaling and polarization of body axes during oogenesis {Ray and Sch6pbach), 1711- 1723 Review

JNK pathway mediating morphogenesis and an immune response (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759- 2768


prevention of Dpp autoactivation and suppression of neurogenesis by sog (Biehs et al.), 2922-2934

Rasl regulation of prospero transcription during eye development (Kauffmann et al.), 2167-2178

RB-related gene RBF (Duet al.), 1206- 1218

regulation of eye development by Dsrc41 (Taka-

hashi et al.), 1645-1656 Rasl-mediated signaling by PP2A

(Wassarman et al.), 272-278 rescue of labial null by chicken or-

tholog Hoxb-1 (Lutz et al.), 176- 184

role of Breathless in patterning cell migra-

tion and branching in the tracheal system (Lee et al.), 2912- 2921


grim in cell death (Chen et al.), 1773-1782

Heartless in cell migration and mesodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017

Lozenge in eye development (Daga et al.), 1194-1205

plx in tracheal function (Zhang et al.), 1108-1119

porcupine in Wingless processing (Kadowaki et al.), 3116-3128

short-range repressors in regulation of complex loci (Gray and Levine), 700-710

TFIIA during RAS-mediated photoreceptor determination (Zeidler et al.), 50-59

trachealess in embryonic tube formation (Isaac and Andrew), 103-117


Vein in EGF pathway (Schnepp et al.), 2302-2313

segmentation and specification of mesoderm (Azpiazu et al.), 3183- 3194

translational regulation of nanos mRNA (Dahanukar and Whar- ton), 2610-2620

translational repression of unlocalized nanos mRNA (Smibert et al.), 2600-2609

truncation of S phase during the endocycle (Lilly and Spradling), 2514-2526

DSBs. See DNA breaks, double-stranded Dsre41, regulation of Drosophila eye

(Takahashi et al.), 1645-1656 Dysplasia, of retinal tissue in p107 null

mice (Lee et al.), 1621-1632

E-box-binding proteins, specificity in gene activation by Myc (Desbar- ats et al.), 447-460

E-cadherin, in Drosophila epithelial cell rearrangement (Uemura et al.), 659-671; (Tepass et al.), 672- 685

E1A, role of p300/CBP and bHLH proteins in cell differentiation (Eckner et al.), 2478-2490

E1B 19K protein, functional interaction with Bax (Han et al.), 461-477

E26 leukemia virus, suppression of apoptosis by v-Myb (Frampton et al.), 2720-2731

E2F -induced S phase and requirement for

cyclin E (Duronio et al.), 2505- 2513

induction of S phase and apoptosis by ectopic expression in Droso- phila (Asano et al.), 1422-1432

protection of E2F-1 from ubiquitin- proteasome degradation pathway by Rb (Hofmann et al.), 2949-2959

regulation of degradation by Rb family proteins

and adenovirus transforming proteins (Hateboer et al.), 2960- 2970

in Drosophila by Rb-related gene (Du et al.), 1206-1218

E2F-1, DNA binding ability in presence of dominant-negative cdk3 (Hof- mann and Livingston), 851-861

Effective concentration, thermodynamic contribution of the linker in Oct-1 POU domain DNA binding (Klemm and Pabo), 27-36

EGF. See Epidermal growth factor EGF receptor. See Epidermal growth fac-

tor receptor egr-1, induction by PKC-~ overexpres-

sion (Kieser et al.), 1455-1466 EKLF. See Erythroid Krfppel-like factor Elk-l, Pax-5 recruitment to a B-cell-spe-

cific promoter (Fitzsimmons et al.), 2198-2211

Embryogenesis abnormalities in Brcal-null mice (Liu

et al.), 1835-1843 degradation of maternal Cdc25

mRNAs in Drosophila maternal/zygotic transition (Edgar and Datar), 1966-1977

effect of dominant-negative Wnt on MyoD induction in Xenopus (Hoppler et al.), 2805-2817

gradual activation of transcription in Drosophila (Pritchard and Schu- biger), 1131-1142

role of BMPs (Hogan), 1580-1594 Review pescadillo and dead eye in zebrafish

(Allende et al.), 3141-3155 signal transduction through ~-cate-

nin (Miller and Moon), 2527- 2539 Review

SL1 RNA in C. elegans (Ferguson et al.), 1543-1556

trachealess in Drosophila (Wilk et al.), 93-102



Endocycle, role of cyclin E in truncation of S phase (Lilly and Spradling), 2514-2526

Endoderm, mechanism of hepatic specification in gut development (Gualdi et al.), 1670-1682

Enhancers Fab-7

attenuation of interactions with promoter in Drosophila (Zhou et al.), 3195-3201

as chromatin domain boundary in Drosophila (Hagstrom et al.), 3202-3215

in the study of position-effect variegation (Wakers et al.), 185-195

Epidermal growth factor, role of Vein in Drosophila signaling pathway (Schnepp et al.), 2302-2313

Epidermal growth factor receptor, role of CF2 in EGF-R-activated dorsoventral patterning (Hsu et al.), 1411-1421

Epidermis, effects of keratinocyte growth factor gene inactivation (Guo et al.), 165-175

Epidermolysis bullosa, plectin mutation

in MD-EBS in humans (McLean et al.), 1724-1735

Epididymis, role of c-ros in epithelial development (Sonnenberg-Rieth- reacher et al.), 1184-1193

Epistasis tests, to confirm branched signaling pathway in Myxococcus (Sogaard-Andersen et al.), 740- 754

Epithelial-mesenchymal interactions, regulation of inductive tissue interactions by Lefl expression (Kratochwil et al.), 1382-1394

Epithelium intestinal, role of cadherins in cell mi-

gration (Hermiston et al.), 985- 996

mammary, regulation of tumor cell plasticity by TGF-~ and Ha-Ras (Oft et al.}, 2462-2477

nasal, role of mouse Pax6 in development (Quinn et al.), 435-446

regulation of growth and differentiation by nude locus product Whn (Brissette et al.), 2212-2221

role of c-ros in development (Sonnenberg-

Riethmacher et al.), 1184-1193 E-cadherin in development in

Drosophila (Uemura et al.}, 659-671; (Tepass et al.), 672-685

seminiferous, degeneration in RXR~- deficient mice {Kastner et al.), 80--92

EpoR. See Erythropoietin receptor Epstein-Barr virus, transcriptional acti-

vation by ZEBRA protein (Chi and Carey), 2540-2550

ERK, stimulation resulting in phosphorylation of HSF1 (Knauf et al.), 2782-2793

ERK2, regulation of developmental pathways in Dictyostelium discoideum (Gaskins et al.), 118-128

Errata Lane et at., 365 Goodrich et al., 904 Kaufmann et al., 1296 McGonigle et al., 2235 Polyak et al., 2818

Erythroid Krfippel-like factor, role in human [3-globin gene competition (Wijgerde et al.), 2894- 2902

Erythropoiesis, effects of erythropoietin receptor gene inactivation (Lin et al.), 154-164

Erythropoietin receptor, effects of gene disruption on primitive and definitive erythropoiesis (Lin et al.), 154-164

Escherichia coli ~CTD DNA-binding determinants of

RNA polymerase (Gaal et al.), 16-26


dif resolvase site insertions (Kuempel et al.), 1162-1171; Corrigen- dum, 1709

HF-1 role in rpoS translation (Muffler et al.), 1143-1151

preferred selection of X recombination hotspot by RecA protein (Tracy a n d Kowalczykowski), 1890- 1903

restriction of dif site activity (Cornet et al.}, 1152-1161

SurA role in outer membrane porin assembly (Rouvihre and Gross), 3170-3182

Estl, single-stranded telomere end-binding protein properties (Virta- Pearlman et al.), 3094-3104

Ets family PU.1 ternary complex formation with

Pip (Brass et al.), 2335-2347 recrui tment by Pax-5 to a B-cell-spe-

cific promoter (Fitzsimmons et al.}, 2198-2211

even-skipped, role in segmentation and specification of Drosophila mesoderm (Azpiazu et al.), 3183- 3194

EVES motif, role in regulation of c-Myb (Dash et al.), 1858-1869

Exons coconversion biases accompanying in-

tron homing (Mueller et al.), 2158-2166

role of hrp45 in binding and nucleocytoplasmic transport of mRNA (Alzhanova-Ericsson et al.), 2881-2893

Exonuclease, 3 ' -~5' , role in 5.85 RNA synthesis {Mitchell et al.), 502- 513

Export, nuclear Npl3p as mediator of RNA export (Lee

et al.), 1233-1246 role of RNA helicase-like protein

HRH1 (Ohno and Shimura), 997-1007

regulation of mRNA export during stress in yeast (Saavedra et al.), 1608-1620

extramacrochaetae, role of Drosophila tamou in activating pathway (Takahisa et al.), 1783-1795

F

Fab-7 at tenuation of enhancer-promoter in-



Fat body, role of serpent in Drosophila (Azpiazu et al.), 3183-3194

FEM-2, role in C. elegans sex determina-

tion (Chin-Sang and Spence), 2314-2325

FEM-3, role of interaction with FEM-2 in C. elegans sex determination (Chin-Sang and Spence}, 2314-- 2325

Fertility effect of Bmp8b inactivation in mice

(Zhao et al.), 1657-1669 male, role of c-ros (Sonnenberg-Rieth-

macher et al.), 1184-1193 FGF receptor. See Fibroblast growth fac-

tor receptor Fibroblast growth factor receptor, role of

Drosophila homolog Heartless in cell migration and mesodermal lineage development (Be- iman et al.), 2993-3002; (Gissel- brecht et al.), 3003-3017

Fibroblasts, human, p53-dependent cell cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947

Fission yeast. See Yeast, fission fkh. See fork head flp recombinase, to delete enhancers in

the study of position-effect variegation (Wakers et al.), 185- 195

Fins, role in p150 ship signal transduction (Lioubin et al.), 1084-1095

Footprinting, genomic, for analysis of cell-cycle regulation of SBF binding (Koch et al.), 129-141

Forebrain, ventral, role of T/EBP in organogenesis (Kimura et al.), 60-69

fork head. control of trachealess expression in the Drosophila salivary duct {Isaac and Andrew), 103- 117

frizzled, similarity of lin- 17 in C. elegans (Sawa et al.), 2189-2197

Fruiting body aggregation, role in C-factor signaling in Myxococcus (Sogaard-Andersen et al.), 740- 754

frz locus, mapping of class I C-factor signaling mutat ions in Myxococ- cus (Sogaard-Andersen et al.), 740-754

FrzCd, C-signaling and traveling wave propagation in Myxococcus {Sager), 2237-2250 Review

FtsZ, bipolar localization in B. subtilis (Levin and Losick), 478-488

Go/G ,, p53-dependent cell-cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947

G2, displacement of SBF from promoters during (Koch et al.), 129-141

GADD45, p53-dependent induction (Ko and Prives}, 1054-1072 Review

GAGA factor, role in altering chromatin structure (Kingston et al.), 905- 920 Review

G a l l l P findings presented at Cold Spring Har-

bor meeting (McKnight), 367- 381 Meeting commentary

gene activation by interaction with GAL4 (Farrell et al.), 2359-2367

GAL4, gene activation by interaction with GALl lP (Farrell et al.), 2359-2367

Galactosialidosis, role of mutan t human neuraminidase gene (Bonten et al.), 3156-3169

Gene disruption. See also Gene inactivation

Bmp8b inactivation in mice (Zhao et al.), 1657-1669

EKLF inactivation on [3-globin transcription in mice {Wijgerde et al.), 2894-2902

p107 inactivation in mice (Lee et al.), 1621-1632

simultaneous inactivation of p107 and p130 in mice (Cobrinik et al.), 1633-1644

expression activator-dependent regulation of

transcriptional pausing on nucleosomal templates (Brown et al.), 1479-1490

differential adipogenic activity of mult iple PPAR isoforms (Brun et al.), 974-984

role of histone amino termini {Ling et al.), 686-699

inactivation. See also Gene disruption ATM disruption in mice {Xu et al.),

2411-2422 Bmp8b disruption in mice (Zhao et

al.), 1657-1669 EKLF disruption on [~-globin tran-

scription in mice (Wijgerde et al.), 2894-2902

erythropoietin receptor (Lin et al.), 154-164

Hlx homeo box gene in mice (Hentsch et al.), 70-79

keratinocyte growth factor (Guo et al.), 165-175

p107 disruption in mice (Lee et al.), 1621-1632

RXR[3 in mice (Kastner et al.), 80-92 simultaneous disruption of p107 and

p130 in mice (Cobrinik et al.), 1633-1644

thyroid-specific enhancer-binding factor in mice (Kimura et al.), 60-69

rearrangement, productive T-cell receptor [3-chain formation (Hoff- man et al.), 948-962

regulation, independent regulation of neighboring genes (Merli et al.), 1260-1270

replacement, targeted, to study inde-


pendent regulation of neighboring genes (Merli et al.), 1260- 1270

Genetic imprinting. See Imprinting, genetic

Genomic footprinting. See Footprinting, genomic

Genomic stability, role of p53 (Ko and Prives), 1054-1072 Review

Germ cell, male, effect of BmpSb inactivation in mice (Zhao et al.), 1657-1669

Germ-line passage, requirement for es- tabl ishment of methylat ion of imprinted genes (Tucker et al.), 1008-1020

GLI family, activation of patched by Cu- bitus interruptus in response Hedgehog signaling (Alexandre et al.), 2003-2013

Globin gene competition, role of EKLF (Wijgerde et al.), 2894-2902

Glossyl5, role in maize leaf development (Moose and Sisco), 3018- 3027

Glucocorticoid receptor mechanism for interpreting signaling

information {Starr et al.), 1271- 1283

role of Swp73 in transcriptional activation (Cairns et al.), 2131-2144

Glucose, regulation of yeast SNF1 interactions (Jiang and Carlson), 3105-3115

Glycogen synthase, regulation of ~-catenin by Xgsk-3 (Yost et al.), 1443-1454

Glycoproteins, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777-793

gpdl, induction by Styl and Atfl in S. pombe (Wilkinson et al.), 2289- 2301

GR. See Glucocorticoid receptor Grb2, role of inositol phosphatases in

signal transduction (Majerus), 1051-1053 Minireview

grim, novel cell death gene in Droso- phila (Chen et al.), 1773-1782

Group I introns, as mobile genetic elements (Mueller et al.), 351-364

Growth arrest, genetic determinants of p53 in-

duction (Polyak et al.), 1945- 1952; Erratum, 2818

cones, regulation of neurite outgrowth by cdkS/p35 kinase (Nikolic et al.), 816--825

factors, role of single factors in CNS stem-cell differentiation {Johe et al.), 3129-3140

inhibition, resulting from p21 elevation by C/EBP~ (Timchenko et al.), 804-815

GT sequences, selection as preferred DNA pairing sequences by E.

coli RecA protein (Tracy and Kowalczykowski), 1890-1903

Gut, hypoplasia in mice deficient for HIx (Hentsch et al.), 70-79

H

HI9, role of DNA methylat ion in regulating expression (Tucker et al.), 1008-1020

Hair, effects of keratinocyte growth factor gene inactivation (Guo et al.), 165-175

Heart role of Heartless in Drosophila devel-

opment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017

specification in Drosophila (Azpiazu et al.), 3183-3194

Heartless, role in Drosophila cell migration and mesodermal lineage development (Beiman et al.), 2993-3002; (Gisselbrecht et al.), 3003-3017

Heat shock effect on subcellular localization of

poly(A) + RNA in yeast (Saave- dra et al.), 1608-1620

factors regulation of HSF1 by phosphoryla-

tion (Knauf et al.), 2782-2793 role in activation of metal lothionein

by oxidative stress (Liu and Thiele), 592-603

use of HSF1 activation domain to readthrough transcriptional pausing (Brown et al.), 1479-1490

genes activator-dependent release of tran-

scriptional pausing on the hsp70 gene {Brown et al.), 1479- 1490

findings presented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary

ribosome jumping in treated cells (Yueh and Schneider), 1557- 1567

hedgehog, role in segmentation and specification of Drosophila mesoderm (Azpiazu et al.), 3183- 3194

Hedgehog family

PKA as a negative regulator (Ham- merschmidt et al.), 647-658

role of signaling in activation of patched by cubitus interruptus (Alexandre et al.), 2003-2013

signaling induction of patched in mice (Goo-

drich et al.}, 301-312 positive regulation of araucan and

caupolican by Ci (G6mez-

Skarmeta and Modolell), 2935- 2945

Helicase, role of RNA helicase-like protein HRH1 in nuclear export (Ohno and Shimura), 997-1007

Hel ix- loop-hel ix proteins, basic bHLH-PAS protein as inducer of

Drosophila tracheal cell fates (Wilk et al.), 93-102

role of ADD1/SREBP1 in adipocyte dif-

ferentiation (Kim and Spiegel- man), 1096-1107

in cell differentiation Eckner et al.), 2478-2490

Helix-loop--helix/leucine zipper proteins, specificity m gene activation by Myc (Desbarats et al.), 447-460

Hematopoeisis, impairment in mice deficient for Hlx (Hentsch et al.), 70-79

Hematopoietic cells, activation of JNK/ SAPK pathway by HPK1 (Hu et al.), 2251-2264

Hematopoietic progenitor kinase 1, activation of JNK/SAPK pathway (Hu et al.), 2251-2264

Hepatocytes, cell-cycle arrest from p21 overexpression in transgenic mice (Wu et al.), 245-260

Heterochromatin, role of silencers in inheritance of repression in yeast (Holmes and Broach), 1021- 1032

High mobil i ty group proteins, transcriptional s t imulat ion by NHP6A/B (Paull et al.), 2769-2781

Hippocampus, role of TrkB and TrkC in promoting neuron survival (Minichello and Klein), 2849- 2858

Histone mRNA, SLBP as novel RNA- binding protein required for processing (Wang et al.), 3028-3040

Histones role of amino termini in nucleosome

assembly (Ling et al.), 686-699 Swel regulator interaction with H3

and H4 amino termini (Ma et al.), 1327-1340

Tupl interaction with H3 and H4 (Ed- mondson et al.), 1247-1259

HIV. See Human immunodeficiency virus

HLH/LZ proteins. See Helix-loop-he- l ix/ leucine zipper proteins

hnRNPs. See Ribonucleoproteins HO, role of Swp73 in expression (Cairns

et al.), 2131-2144 Holoenzyme

gene activation by GAL4--GAL11P interaction (Farrell et al.), 2359- 2367

role in Pol II transcription (Orphanides et al.), 2657-2683 Review


Homeo box genes Hlx is essential for expansion of

mouse embryonic liver and gut (Hentsch et al.), 70-79

novel bicoid-related homeo box factor Ptxl (Lamonerie et al.), 1284-- 1295


regulation of araucan and caupolican during Drosophila wing development (G6mez-Skarmeta and Modolell), 2935-2945

HOM-C genes, rescue of Drosophila labial null by chicken ortholog Hoxb-1 (Lutz et al.), 176--184

Hox genes in vivo mutagenesis of required HoxD

complex regulatory element (G4rard et al.), 2326-2334

rescue of Drosophila labial null by chicken ortholog Hoxb-I (Lutz et al.), 176-184

Hoxb-1, chicken, rescue of Drosophila labial null (Lutz et al.), 176-184

HoxD complex, in vivo mutagenesis of required regulatory element (G4rard et al.), 2326--2334

HPK1. See Hematopoietic progenitor kinase 1

HPR1, role of protein product in yeast telomeric size control (Li and Lustig), 1310-1326

HRH1, role in nuclear export (Ohno and Shimura), 997-1007

HSF. See Heat shock factors HSF1, regulation by phosphorylation

(Knauf et al.), 2782-2793 HSL1, interaction of protein product

with histone amino termini (Ma et al.), 1327-1340

HSL7, interaction of protein product with histone amino termini (Ma et al.), 1327-1340

Hsp70 gene family hsp70 activator-dependent release of

transcriptional pausing (Brown et al.), 1479-1490

nucleocytoplasmic export of SSA4 mRNA during stress in yeast (Saavedra et al.), 1608-1620

Hsp90, p50 Cdr as protein kinase-targeting subunit (Stepanova et al.), 1491-1502

Human immunodeficiency virus, chromatin reconfiguration and transcriptional activation of the HIV-1 enhancer by NF-KB (Pa- zin et al.), 37-49

ICE-related cysteine proteases induction by BID, a novel death ago-

nist possessing only a BH3 do-

main (Wang et al.), 2859-2869 role in



substrate specificities (Xue et al.), 1073-1083

IGF-BP3, as transcriptional target of p53 (Ko and Prives), 1054-1072 Re- view

Igf2, role of DNA methylation in regulating gene expression (Tucker et al.), 1008-1020

Igf2r, role of DNA methylation in regulating gene expression (Tucker et al.), 1008-1020

Immune response, mediation by Drosophila JNK pathway (Sluss et al.), 2745-2758

Immune system coincident regulation of cell cycle and

clonality during T-cell receptor development (Hoffman et al.), 948-962

defects in ATM-deficient mice (Xu et al.), 2411-2422

role of ATM (Hawley and Friend), 2383-2388 Review

Immunofluorescence microscopy, to study localization of FtsZ in B. subtilis (Levin and Losick), 478- 488

Immunoglobulin production, role of Pip ternary complex formation with PU.1 (Brass et al.), 2335-2347

Imprinting, genetic, role of DNA methylation (Tucker et al.), 1008- 1020

Imprinting, genomic, role of DNA methylation (Tucker et al.), 1008-1020

Induction of egr-1 by PKC-~ overexpression

(Kieser et al.), 1455-1466 of junB by PKC-~ overexpression

(Kieser et al.), 1455-1466 of metanephric mesenchyme differen-

tiation by Winged Helix protein BF-2 (Hatini et al.}, 1467-1478

IFN. See Interferon Initiator element, role

binding of Drosophila TFIID to downstream basal promoter element (Burke and Kadonaga), 711-724

CIF as cofactor for TFIID-dependent function [Kaufmann et al.), 873- 886

Inositol polyphosphate 5-phosphatases p150 ship and Fms signal transduction

{Lioubin et al.), 1084-1095 role in signal transduction (Majerus),

1051-1053 Minireview Inositols

inositol polyphosphate 5-phosphatases (Majerus), 1051-1053 Minire- view

p150 ship and Fms signal transduction (Lioubin et al.), 1084-1095

Inr. See Initiator element Insertional mutagenesis. See Mutagene-

sis, insertional Insulators, Fab-7

attenuation of enhancer-promoter interactions in Drosophila (Zhou et al.), 3195-3201


Integration, transposon targeting of retrotransposon Tyl to up-

stream regions of RNA pol II- transcribed genes (Devine and Boeke), 620-633

of Ty5 into regions of silent chromatin (Zou et al.), 634-645

Intercellular signaling, cAMP and traveling wave propagation in Dicty- ostelium (Sager), 2237-2250 Re- view

Interferon effect on expression of PML and POD

reorganization (Doucas et al.), 196-207

regulatory factor family, Pip autoinhibition and ternary complex formation with PU.1 (Brass et al.), 2335-2347

Intestines, role of cadherins in epithelial cell migration (Hermiston et al.), 985-996

Intracellular receptor family, common mechanism for interpreting signaling information at response elements [Starr et al.), 1271- 1283

Intracellular transduction, cAMP and traveling wave propagation in Dictyostelium (Sager), 2237- 2250 Review

Intron enhancer, role in activation of polya-

denylation {Lou et al.), 208-219 exon coconversion biases accompany-

ing homing (Mueller et al.), 2158-2166

homing, pathways in T4 phage (Muel- let et al.), 351-364

Inverted repeat-binding protein, as Drosophila homolog of Ku p70 (Beall and Rio), 921-933

IP5Pases. See Inositol polyphosphate 5-phosphatases

IR family. See Intracellular receptor family

IRBP. See Inverted repeat-binding protein

IRF family. See Interferon regulatory factor family

islet [~ cells, rise and fall of apoptosis during multistage tumorigenesis (Naik et al.), 2105-2116

Isomerase, peptidyl-prolyl, role of SurA


in protein folding in E. coli (Rouvi6re and Gross), 3170- 3182

Isomerase, prolyl, mammalian RAFT1 as target of FKBPl2-rapamycin (Alarcon et al.1, 279-288

JNKs. See c-Jun amino-terminal kinases junB, induction by PKC-~ overexpres-

sion (Kieser et al.), 1455-1466

K

KAP-1, identification as KRAB domain corepressor (Friedman et al.), 2067-2078

Keratinocyte growth factor, effects of gene inactivation (Guo et al.), 165-175

Keratinocytes p21 role in growth and differentiation

(Missero et al.), 3065-3075 regulation of epithelial growth and dif-

ferentiation by nude locus product Whn (Brissette et al.), 2212- 2221

Src-family kinases role in differentiation (Lowell and Soriano), 1845- 1857 Review

KGF. See Keratinocyte growth factor Kidney, COL4A3-deficient mice as

model for Alport syndrome (Cosgrove et al.), 2981-2992

Kinase suppressor of Ras, role in MAPK signaling pathway (Therrien et al.), 2684-2695

Kinases Atr- and Atm-associated activity (Kee-

gan et al.), 2423-2437 characterization of a novel nuclear ki-

nase in human cells (Denis and Green), 261-271

Digl and Dig2 as substrates of Kssl in S. cerevisiae (Cook et al.), 2831- 2848

function of human TOR homolog RAFT1 (Alarcon et al.), 279-288

glucose regulation of yeast SNF1 complex interactions (Jiang and Carlson), 3105-3115

interaction of Swel regulators with histone amino termini (Ma et al.), 1327-1340

regulation of Atfl by Styl in S. pombe (Wilkinson

et al.), 2289-2301 [3-catenin by Xgsk-3 (Yost et al.),

1443-1454 role of Xenopus Sucl homolog Xe-p9

in cell cycle control (Patra and Dunphy), 1503-1515

serine, role in stress response signaling

in B. subtilis (Yang et al.), 2265- 2275


Src-family, effects of gene disruptions in mice (Lowell and Soriano), 1845-1857 Review

tyrosine, regulation of Drosophila eye development by Dsrc41 (Taka- hashi et al.), 1645-1656

Kluyveromyces lactis, role of cap-prevented recombination in telomere maintenance (McEachern and Blackburn), 1822-1834

KRAB domain. See Krfippel-associated box domain

Krfippel, as transcriptional repressor (Gray and Levine), 700-710

Kr/ippel-associated box domain, identification of KAP-1 as corepressor (Friedman et al.), 2067-2078

KSR. See Kinase suppressor of Ras Ku, encoding of p70 homolog IRBP by

Drosophila mus309 Beall and Rio), 921-933

L

labial, rescue of gene inactivation in Drosophila by chicken ortholog Hoxb-1 (Lutz et al.), 176-184

LCR. See Locus control region Lefl, regulation of inductive tissue inter-

actions (Kratochwil et al.), 1382-1394

Lens, role of mouse Pax6 in eye development (Quinn et al.), 435-446

Leucine zipper proteins basic

cloning of Atfl and Atf21 in S. pombe (8hiozaki and Russell), 2276-2288

regulation of Atfl by Styl in S. pombe (Wilkinson et al.), 2289- 2301

role of ADD1/SREBP1 in adipocyte differentiation (Kim and Spiegelman), 1096-1107

Leukemia elevation of a novel nuclear kinase in

acute and chronic lymphocytic (Denis and Green), 261-271

suppression of myeloid cell apoptosis by E26 v-Myb (Frampton et al.), 2720-2731

LIM motifs, two interacting surfaces of (Arber and Caroni), 289-300

LIM proteins, specificity of LIM-based interactions (Arber and Caroni), 289--300

Limb buds, role of BMPs in patterning (Hogan), 1580-1594 Review

lin-4, role of duplex formation with lin- 14 in down-regulation of trans-

lation (Ha et al.), 3041-3050 lin-14, role of 3' UTR in down-regulation

of translation (Ha et al.), 3041- 3050

lin-17, role in asymmetric cell division in C. elegans (Sawa et al.), 2189-2197

LIN-44, LIN-17 as receptor for asymmetric cell division in C. elegans (Sawa et al.), 2189-2197

Lineage analysis, posterior patterning by vab-7 (Ahringer), 1120-1130

Lipid metabolism, in Sertoli cells of RXR[3-deficient mice (Kastner et al.), 80-92

Liver accelerated apoptosis in plO7-null

mice (Lee et al.), 1621-1632 hypoplasia in mice deficient for Hlx

(Hentsch et al.), 70-79 mechanism of hepatic specification of

gut endoderm (Gualdi et al.), 1670-1682

regeneration, effect of p21 overexpression in transgenic mice (Wu et al.), 245-260

Localization nuclear

colocalization of APETALA3 and PISTILLATA (McGonigle et al.), 1812-1821

of Madr2 in response to activin (Baker and Harland), 1880-1889

subcellular anticodon as signal sequence for

tRNA import into mitochondria (Rusconi and Cech), 2870- 2880

of TFIID and inhibition of activator- dependent transcription (Segil et al.), 2389-2400



Locus control region, role of EKLF in human [3-globin gene competition (Wijgerde et al.), 2894-2902

Lon protease, role of in cell-cycle control of DNA methylation (Wright et al.), 1532-1542

Lozenge, role in Drosophila eye development (Daga et al.), 1194-1205

Lung, role of T/EBP in organogenesis (Kimura et al.), 60-69

Lymphocytes activation of DNA damage checkpoint

by V(D)J recombination in scid mice (Guidos et al.), 2038-2054

effects of ATM disruption in mice (Xu et al.), 2411-2422


Lymphoma


in ATM-deficient mice (Xu et al.), 2411-2422


Lymphomagenesis, cooperativity of p53 and SCID genes (Nacht et al.), 2055-2066

Lysosome, identification of human neuraminidase gene and role in sialidosis (Bonten et al.), 3156-3169

M

Madr2, participation in the activin signal transduction pathway (Baker and Harland), 1880-1889

Magnaporthe grisea, MAP kinase and cAMP regulation of infection (Xu and Hamer), 2696-2706

MAGUK proteins. See Membrane-associated guanylate kinase proteins

Maize, role of Glossyl5 in leaf development (Moose and Sisco), 3018- 3027

MAP kinase pathway DIGI and DIG2 as two novel targets

in S. cerevisiae (Cook et al.), 2831-2848

Drosophila JNK pathway mediating morphogenesis and an immune response (Sluss et al.), 2745- 2758; {Riesgo-Escovar et al.), 2759-2768

inhibition of JNK/SAPK activation by HPK1 (Hu et al.), 2251-2264

Rasl regulation of prospero transcription during Drosophila eye development (Kauffmann et al.), 2167-2178

regulation of Atfl by Spcl in S. pombe (Shiozaki

and Russell), 2276-2288 Atfl by Styl in S. pombe (Wilkinson

et al.), 2289-2301 developmental pathways by ERK2

in Dictyostelium discoideum {Gaskins et al.), 118-128

rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706

role of KSR (Therrien et al.), 2684- 2695

stimulation of Raf/ERK resulting in phosphorylation of HSF 1 (Knauf et al.), 2782-2793

MAP4. See Microtubule-associated protein

Maternal/zygotic transition, role of degradation of maternal Cdc25 mRNAs (Edgar and Datar), 1966-1977

Mating-type locus effects of telomere proximity and Sir

protein concentration on silencing {Maillet et al.), 1796-1811

role of

Rapl protein in silencing (Marcand et al.), 1297-1309

silencers in inheritance of repression in yeast (Holmes and Broach), 1021-1032

Max, role in specific gene activation by Myc {Desbarats et al.), 447-460

rob-1 promoter, Pax-5 recruitment of Ets proteins (Fitzsimmons et al.), 2198-2211

MD-EBS. See Muscular dystrophy; see also Epidermolysis bullosa

mdm-2, as transcriptional target of p53 {Ko and Prives), 1054-1072 Re- view

Mdx, and MyoD in muscle regeneration (Megeney et al.), 1173-1183

Mecl, regulation of Spkl/Rad53 (Sun et al.), 395-406

Mec2, regulation by Mecl-dependent protein phosphorylation {Sun et al.), 395-406

Meioisis association with paired chromosomes

(Keegan et al.), 2423-2437 effects of ATM disruption in mice (Xu

et al.), 2411-2422 regulation by Spcl through Atfl tran-

scription in S. pombe {Shiozaki and Russell), 2276-2288

role of ATM in recombination (Haw- ley and Friend), 2383-2388 Re- view

MEK, effects of KSR cooperation with Ras (Therrien et al.), 2684-2695

Membrane-associated guanylate kinase proteins, identification of Drosophila ZO-1 homolog tamou (Takahisa et al.), 1783- 1795

Menadione, strong activation of yeast CUP1 (Liu and Thiele), 592-603

Mesenchyme, stromal, essential role in kidney morphogenesis (Hatini et al.}, 1467-1478

Mesoderm effect of dominant-negative Wnt on

development in Xenopus embryos (Hoppler et al.), 2805- 2817

paraxial, role of mouse Wnt-3a in formation (Greco et al.), 313-324

role of C. elegans sem-4 in development

(Basson and Horvitz), 1953- 1965

Heartless in Drosophila development (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017

Madr2 in induction (Baker and Hat- land), 1880-1889

segmentation and specification in Drosophila (Azpiazu et al.), 3183-3194

Messenger RNA

increase in polyadenylation efficiency (Lutz et al.), 325-337

precursors effects of U1 snRNA on 5' splice site

selection (Hwang and Cohen), 338-350

nuclear cap-binding complex role in recognition and splicing (Lewis et al.), 1683-1698

redundant interactions between U2 and U6 snRNAs during splicing (Field and Friesen), 489-501

SLBP role in processing histone pre- mRNA (Wang et al.), 3028-3040

U2AF 35-kD subunit role in splicing (Zuo and Maniatis), 1356-1368

RNA helicase-like protein HRH1 role in nuclear export (Ohno and Shimura), 997-1007


U2AF 35-kD subunit role in splicing (Zuo and Maniatis), 1356-1368

Metal response elements, use of the metallothionein enhancer to study position-effect variegation (Wai- ters et al.), 185-195

Metal-binding proteins, activation of metallothionein by oxidative stress via HSF (Liu and Thiele), 592-603

Metallothionein activation by oxidative stress via HSF

{Liu and Thiele), 592-603 enhancer, in the study of position-ef-

fect variegation (Walters et al.), 185-195

Metanephros, induction of differentiation by Winged Helix protein BF-2 (Hatini et al.), 1467-1478

Methylation activation of Xist by DNA hypometh-

ylation (Panning and Jaenisch), 1991-2002

role of Lon protease in Caulobacter (Wright et al.), 1532-1542

Methyltransferase activity during oogenesis and sper-

matogenesis (Tucker et al.), 1008-1020

CcrM as target of Lon protease in Cau- lobacter (Wright et al.), 1532- 1542

Microtubule -associated protein, negative regula-

tion of MAP4 expression by p53 (Murphy et al.), 2971-2980


Migration, neuronal, effects of Tst-1/ Oct-6/SCIP deletion in mice {Bermingham et al.), 1751-1762

MIS. See Mfillerian-inhibiting substance Mismatch repair


eukaryotic, biochemistry and genetics (Kolodner), 1433-1442 Review

prokaryotic, similarities of eukaryotic pathways (Kolodner), 1433- 1442 Review

redundancy of MSH3 and MSH6 (Mar- sischky et al.), 407--420

Mitochondria, anticodon as signal sequence for tRNA import (Rusconi and Cech), 2870-2880

Mitosis Bcl-x L and p53 in checkpoint control

(Minn et al.), 2621-2631 inhibit ion of activator-dependent tran-

scription (Segil et al.), 2389- 2400

role of topoisomerases in chromosome condensation in S. cerevisiae (Castaho et al.), 2564-2576

MLP, LIM-mediated interaction with the actin cytoskeleton (Arber and Caroni), 289-300

MMTV. See Mouse mammary tumor virus

Morphogenesis branching, role of Breathless in Droso-

phila (Lee et al.), 2912-2921 C-signaling and traveling wave propa-

gation in Myxococcus (Sager), 2237-2250 Review

cAMP and and traveling wave propagation in Dictyostelium (Sager), 2237-2250 Review

cell, role of Axl2p in bud site selection in yeast (Roemer et al.), 777- 793

egg cylinder, failure in Brcal-null mice (Liu et al.), 1835-1843

epithelial, role of E-cadherin in Droso- phila (Uemura et al.), 659-671; {Tepass et al.), 672-685

mediation by Drosophila JNK pathway (Sluss et al.), 2745-2758; (Riesgo-Escovar et al.), 2759- 2768

prevention of Dpp autoactivation and suppression of neurogenesis by Drosophila sog (Biehs et al.), 2922-2934

Mouse mammary tumor virus, rearrangement of Notchl in mouse thymomas in transgenic mice (Girard et al.), 1930-1944

MREs. See Metal response elements mRNA. See Messenger RNA MSH2, role in mismatch repair and re-

dundancy of MSH3 and MSH6 (Marsischky et al.), 407-420

MSH3, redundancy with MSH6 in MSH2-dependent mismatch repair (Marsischky et al.), 407- 420

MSH6, redundancy with MSH3 in MSH2-dependent mismatch repair (Marsischky et al.), 407- 420

M611erian-inhibiting substance, role in mammalian sexual differentiation (Mishina et al.), 2577-2587

MUD13, identification of protein product as yeast homolog of CBP20 (Color et al.), 1699-1708

Multiprotein complexes, LIM motifs as specific adaptor elements (Arber and Caroni), 289-300

Muscle cells, role of p300/CBP and bHLH pro-

teins in differentiation (Eckner et al.), 2478-2490

effect of dominant-negative Wnt on development in Xenopus embryos (Hoppler et al.), 2805- 2817

regeneration, role of MyoD in myogenic stem cell function (Megeney et al.), 1173-1183

role of Heartless in Drosophila development (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017

skeletal regulation of development by Rb

(Zackenhaus et al.), 3051-3064 role of MyoD in myogenic stem cell

function (Megeney et al.), 1173- 1183

Muscular dystrophy plectin mutat ion in MD-EBS in hu-

mans (McLean et al.), 1724- 1735

role of MyoD in myogenic stem cell function (Megeney et al.), 1173- 1183

Musculature, visceral, role of bagpipe in Drosophila (Azpiazu et al.), 3183-3194

Mutagen sensitivity, encoding of Ku p70 homolog IRBP by Drosophila mus309 (Beall and Rio), 921- 933

Mutagenesis insertional

identification of pescadillo and dead eye in zebrafish (Allende et al.), 3141-3155

prospects for use in zebrafish (Schier et al.), 3077-3080 Minireview


MutHLS, comparison of E. coli and eukaryotic mismatch repair pathways (Kolodner), 1433-1442 Re- view

MutL proteins, eukaryotic homologs (Kolodner), 1433-1442 Review

MutS proteins, eukaryotic homologs (Kolodner), 1433-1442 Review

Myb. See also c-Myb CBP as coactivator (Dai et al.), 528-540 regulation of bcl-2 by dominant inter-

fering form (Taylor et al.), 2732- 2744

suppression of apoptosis by E26 v-Myb (Frampton et al.), 2720-2731

Myc. See also c-myc specificity in gene activation (Desbar-

ats et al.), 447-460 Myelination, peripheral, regulation by

Tst-1/Oct-6/SCIP in mice (Ber- mingham et al.), 1751-1762

Myeloid cells regulation of bcl-2 by dominant inter-

fering Myb (Taylor et al.), 2732- 2744

role of Src-family kinases in development (Lowell and Soriano), 1845-1857 Review

suppression of apoptosis by E26 v-Myb (Frampton et al.), 2720-2731

Myelomonocytes, vi tamin D 3 and induced differentiation of U937 cells (Liu et al.), 142-153

MyoD induction blocked by dominant-nega-

tive Wnt in Xenopus embryos (Hoppler et al.), 2805-2817

role in myogenic stem cell function (Megeney et al.), 1173-1183

Myogenesis Heartless role in Drosophila develop-

ment (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017

p300/CBP and bHLH proteins roles in muscle cell differentiation (Eck- ner et al.), 2478-2490

regulation of skeletal muscle cell differentiation by Rb (Zackenhaus et al.), 3051-3064

Myoglobin, putative skNAC binding sites in promoter (Yotov and St- Arnaud), 1763-1772

Myxococcus xanthus branched C-factor signaling pathway

in (Sogaard-Andersen et al.), 740-754

C-signaling and traveling wave propagation (Sager), 2237-2250 Re- view

MZT. See Maternal /zygotic transition

N

NAC. See Nascent polypeptide-associated complex

nanos, repression of unlocalized mRNA translation by smaug (Smibert et al.), 2600-2609

Nascent polypeptide-associated complex, conversion of ~NAC to myotube-specific factor (Yotov and St-Arnaud), 1763-1772

Nematodes. See also Caenorhabditis elegans

in vitro transposition of Tcl in C. elegans (Vos et al.), 755-761



Nephron, regulation of development by Winged Helix protein BF-2 (Ha- tini et al.), 1467-1478

Nervous system, central accelerated apoptosis in p107 null

mice (Lee et al.), 1621-1632 plx role in tracheal function (Zhang et

al.), 1108-1119 single factors role in stem cell differ-

entiation (Johe et al.), 3129- 3140

Net, Pax-5 recruitment to a B-cell-specific promoter (Fitzsimmons et al.), 2198-2211

Neuraminidase, identification of human gene and role in sialidosis (Bon- ten et al.), 3156-3169

Neuregulin, similarity of Drosophila Vein (Schnepp et al.), 2302-2313

Neurite outgrowth, regulation cdk5/p35 kinase (Nikolic et al.), 816-825

Neurodegeneration, modulation by interactions between wild-type and mutant prion proteins in mice (Telling et al.), 1736-1750

Neuroectoderm role of E-cadherin in development in

Drosophila (Tepass et al.), 672- 685

suppression of neurogenesis by Droso- phila sog (Biehs et al.), 2922- 2934

Neurogenesis coupling of cell lineage asymmetry


suppression by Drosophila sog (Biehs et al.), 2922-2934

Neurons role of C. elegans sere-4 in develop-

ment (Basson and Horvitz), 1953-1965

role of TrkB and TrkC in promoting survival (Minichello and Klein), 2849-2858

Neurotrophins, role of TrkB and TrkC in promoting neuron survival (Mini- chello and Klein), 2849-2858

NF-KB. See also rel/NFKB proteins induction by TANK (Cheng and Balti-

more), 963-973 -mediated chromatin reconfiguration

and transcriptional activation of HIV-1 enhancer (Pazin et al.), 37-49

NHP6A/B. See Nonhistone proteins 6A and 6B

Nodal, asymmetric expression in vertebrate embryo (Hogan), 1580- 1594 Review

Nonhistone proteins 6A and 6B, role in transcriptional stimulation in S. cerevisiae (Paull et al.), 2769-2781

Notch, role of ligand Delta in Drosophila wing development (Doherty et al.), 421-434

Notchl, rearrangement in mouse T-cell lymphoma (Girard et al.), 1930- 1944

NPL3, role of protein product in RNA export in yeast (Lee et al.), 1233-1246

Nuclear division, role of topoisomerases in chromosome condensation in S. cerevisiae (Castaho et al.), 2564-2576

Nuclear export. See Export, nuclear Nuclear hormone receptors, differential

adipogenic activity of multiple PPAR isoforms (Brune t al.), 974-984

Nuclear organization, POD organization and adenoreplication (Doucas et al.), 196-207

Nuclear pore, role of hrp45 in nucleocytoplasmic transport of mRNAs (Alzhanova-Ericsson et al.), 2881-2893

Nuclear receptors. See Receptors, nuclear

Nucleases, competition in coconversion biases accompanying intron homing (Mueller et al.), 2158-2166

Nucleocytoplasmic ratio, role in gradual activation of transcription in Drosophila (Pritchard and Schu- biger), 1131-1142

Nucleocytoplasmic transport, role of hrp45 in accompanying pre- mRNA to nuclear pores (Alzha- nova-Ericsson et al.), 2881-2893

Nucleosomes in chromatin structure (Kingston et

al.), 905-920 Review role

of histone amino termini in assembly (Ling et al), 686-699

in transcriptional pausing (Brown et al.), 1479-1490

Nude mouse, regulation of epithelial growth and differentiation by nude locus product Whn (Bris- sette et al.), 2212-2221

NURF, role in altering chromatin structure (Kingston et al.), 905-920 Review

Nutrients, stimulation of Tap42 association with PP2A (DiComo and Amdt), 1904-1916

O

OCA-B, sequence-specific DNA binding (Cepek et al.), 2079-2088

Oct-1 POU domain-DNA interactions

(Klemm and Pabo), 27-36 sequence-specific DNA binding of

B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2O88

Oct-2, sequence-specific DNA binding of B-cell POU domain coactivator OCA-B (Cepek et al.), 2079- 2088

Oct-6, effects of gene deletion in mice (Bermingham et al.), 1751-1762

Olfactory tract, effects of Tst-1/Oct-6/ SCIP deletion in mice (Berming- ham et al.), 1751-1762

Oncogenesis, collaboration of c-myc with Notchl in MMTV/myc transgenic mice (Girard et al.), 1930-1944

Oocyte determination, role of cyclin E in S phase during the Drosophila endocycle (Lilly and Spradling), 2514--2526

Oogenesis CF2 role in EGF-R-activated dorsoven-


defects in ATM-deficient mice (Xu et al.), 2411-2422

intercellular signaling and polarization of body axes in Drosophila (Ray and Schiipbach), 1711- 1723 Review

Oskar protein-protein interactions in Drosophila pole plasm formation (Breitwieser et al.), 2179- 2188

ORC regulation of S-phase onset by fission yeast ORC1

homolog orpl (Grallert and Nurse), 2644-2654

and specification of eukaryotic replication origins (Diffley), 2819- 2830 Review

Organogenesis BMPs {Hogan), 1580-1594 Review Hlx in mice (Hentsch et al.), 70-79 pescadillo and dead eye in zebrafish

(Allende et al.), 3141-3155 T/EBP in mice (Kimura et al.), 60-69

Organs, sensory regulation of araucan and caupolican

during Drosophila wing patterning (G6mez-Skarmeta and Modolell), 2935-2945

role of Drosophila tamou in formation (Takahisa et al.), 1783-1795

Origins, replication determinants of late activation (Fried-

man et al.), 1595-1607 regulation and specification of eukary-

otic origins (Diffley), 2819-2830 Review

orpl, regulation of S-phase onset in fission yeast (Grallert and Nurse), 2644-2654

orthodenticle, novel related homeo box factor Ptxl (Lamonerie et al.), 1284-1295


Oskar, role of protein-protein interactions in Drosophila pole plasm formation (Breitwieser et al.), 2179-2188

Osmotic regulation, role of HF-I in E. coli (Muffler et al.J, 1143-1151

OSS1, interaction of protein product with histone amino termini (Ma et al.), 1327-1340

Otx-1, novel related homeo box factor Ptxl (Lamonerie et al.), 1284- 1295

Otx-2, novel related homeo box factor Ptxl (Lamonerie et al.), 1284- 1295

Outer membrane porins, role of SurA in assembly in E. coli (Rouvihre and Gross), 3170-3182

Oxidative stress, activation of metallothionein via HSF (Liu and Thiele), 592-603

P

P element disruption of trachealess in Droso-

phila (Isaac and Andrew), 103- 117

severe reduction of excision in mus309 mutants (Beall and Rio), 921-933

p21 elevation by C/EBP~ and inhibition of

cell proliferation (Timchenko et al.), 804-815

overexpression in transgenic mice (Wu et al.), 245-260

as p53 response gene IKo and Prives), 1054-1072 Review

role in ATM function {Xu and Baltimore),

2401-2410 keratinocyte growth and differentia-

tion (Missero et al.), 3065-3075 p53-dependent cell-cycle arrest in-

duced by ribonucleotide depletion (Linke et al.), 934-947

p53-dependent tumor cell apoptotic response {Chen et al.), 2438- 2451

p53-induced growth arrest (Polyak et al.), 1945-1952; Erratum, 2818

vitamin D 3 induction of (Liu et al.), 142-153

p53 abnormal kidney development in


activation of DNA damage checkpoint by V(D)J recombination (Guidos et al.), 2038-2054

cooperativity with SCID defect in tumorigenesis (Nacht et al.), 2055-2066

current advances (Ko and Prives), 1054-1072 Review

-dependent cell-cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947


genetic determinants of growth arrest versus apoptosis (Polyak et al.), 1945-1952; Erratum, 2818

levels and extent of tumor cell apoptotic response (Chen et al.), 2438-2451

negative regulation of MAP4 expression (Murphy et al.), 2971-2980

rise and fall of apoptosis during multistage tumorigenesis (Naik et al.), 2105-2116

role in apoptosis (White), 1-15 Review ATM function (Hawley and Friend),

2383-2388 Review; (Xu and Bal- timore), 2401-2410

mitotic checkpoint control (Minn et al.), 2621-2631

radiation-induced differentiation and rescue of V(D)J rearrangement in scid mice (Bogue et al.), 553-565

role of XPB and XPD in apoptosis (Wang et al.), 1219-1232

tissue-specific inactivation of tumor suppression in mice (Bowman et al.), 826-835

p107 effect of targeted disruption in mice

(Lee et al.), 1621-1632 shared role of protein product with

p130 in limb development in mice tCobrinik et al.), 1633- 1644

p130, shared role of protein product with p107 in limb d~velopment in mice (Cobrinik et al.), 1633- 1644

p130 c~, role of related protein Sin in c-Src activation (Alexandropou- los and Baltimore), 1341-1355

pl50Ship

Fms signal transduction (Lioubin et al.), 1084-1095

role of inositol phosphatases in signal transduction (Majerus), 1051- 1053 Minireview

p300 interaction with SREBP (Oliner et al.),

2903-2911 role in cell differentiation (Eckner et

al.), 2478-2490 p35 kinase. See cdk5 p50 Cdc37, protein kinase-targeting sub-

unit of Hsp90 (Stepanova et al.), 1491-1502

PAS proteins, bHLH-PAS protein as inducer of Drosophila tracheal cell fates (Wilk et al.), 93-102

patched activation by Gubitus interruptus in

response Hedgehog signaling (Alexandre et al.), 2003-2013

induction by hedgehog in mice (Good- rich et al.), 301-312

Pattern formation posterior patterning by vab-7 (Ahr-

inger), 1120-1130 regulation of araucan and caupolican

during Drosophila wing patterning (G6mez-Skarmeta and Modolell), 2935-2945

rescue of Drosophila labial null by chicken ortholog Hoxb-1 (Lutz et al.), 176-184

role of CF2 in EGF-R-activated Drosophila

dorsoventral patterning (Hsu et al.), 1411-1421

Drosophila Lozenge (Daga et al.), 1194-1205

Patterning dorsoventral

CF2 role in EGF-R-activated dorsoventral patterning (Hsu et al.), 1411-1421

dino and swirl roles in zebrafish (Hammerschmidt et al.), 2452- 2461

embryonic, polarization of body axes during Drosophila oogenesis (Ray and Sch~ipbach), 1711- 1723 Review

role of BMPs (Hogan), 1580-1594 Re- view

wing, role of Delta in Drosophila (Doherty et al.), 421--434

Pax genes, role of Pax6 in mouse development (Quinn et al.), 435--446

Pax-5, recruitment of Ets proteins to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211

Pax6, role in mouse development (Quinn et al.), 435--446

Pdslp, control of anaphase initiation in S. cerevisiae by APC-dependent degradation (Cohen-Fix et al.), 3081-3093

pelle kinase, functional interactions with Toll receptor and tube (Norris and Manley), 862-872

Periplasm, role of SurA in protein folding in E. coli {Rouvihre and Gross), 3170-3182

Peroxisome proliferation-activated receptor, differential adipogenic activity of multiple isoforms (Brunet al.), 974-984

pescadillo, role in zebrafish development (Allende et al.), 3141- 3155

PEV. See Position-effect variegation Phage T4, exon coconversion biases ac-

companying intron homing (Mueller et al.), 2158-2166


Phosphatases ceramide-activated mediates G1 arrest

in Saccharomyces cerevisiae (Nickels and Broach), 382-394

FEM-2 role in C. elegans sex determination (Chin-Sang and Spence), 231 4-2325

inositol phosphatases role in signal transduction (Majerus), 1051- 1053 Minireview

nutrient stimulation of Tap42 association with PP2A (DiComo and Arndt), 1904-1916

p 1 $0 ship and Fms signal transduction (Lioubin et al.), 1084-1095

serine, role in stress response signaling in B. subtilis (Yang et al.), 2265- 2275

SpoIIE in Bacillus subtilis (Feucht et al.}, 794-803

Phosphorylation analysis of key residues for Torso sig-

naling (Cleghon et al.), 566- 577

Digl and Dig2 as substrates of Kssl in S. cerevisiae (Cook et al.), 2831- 2848

regulation of B-catenin by Xgsk-3 (Yost et al.),

1443-1454 HSF1 (Knauf et al.}, 2782-2793

role in activation of dorsal by Toll, tube and



role of FEM-2 phosphatase in C. e/e- gans sex determination (Chin- Sang and Spence), 2314-2325

of Spkl/Rad53 as regulated by Mecl (Sun et al.), 395-406

SpoIIE as phosphatase in Bacillus sub- tills (Feucht et al.}, 794-803

of SR proteins (Manley and Tacke), 1569-1579 Review

of TFIID and inhibition of activator- dependent transcription (Segil et al.}, 2389-2400

Photoreceptor cells effects on specification through regu-

lation of Rasl-mediated signaling by PP2A (Wassarman et al.), 272-278

role of Drosophila Lozenge in cell-fate determination (Daga et al.), 1194-1205

Phyllopod, role in upregulation of prospero transcription during Drosophila eye development (Kauffmann et al.), 2167-2178

Pip, autoinhibition and ternary complex formation with PU.1 (Brass et al.), 2335-2347

PISTILLATA, nuclear colocalization

with APETALA3 (McGonigle et al.), 1812-1821

Pituitary abnormalities in Rb +/- mice (Nikitin

and Leel, 1870-1879 expression of bicoid-related homeo

box factor Ptxl (Lamonerie et al.}, 1284--1295

role of T/EBP in organogenesis (Kimura et al.), 60-69

PKA. See Protein kinase A PKI, in Hedgehog signaling as dominant-

negative form of PKA (Hammer- schmidt et al.), 647-658

Plant pathogens, MAP kinase and cAMP regulation of rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706

Plasma membrane proteins, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777- 793

Plasmids, conjugating, as preferred targets for Tn7 (Wolkow et al.), 2145-2157

Plasticity, phenotypic, regulation by TGF-~ and Ha-Ras (Oft et al.), 2462-2477

Plectin, loss and epidermolysis bullosa with muscular dystrophy (McLean et al.), 1724-1735

PMKI, role in rice blast fungus M. grisea infection (Xu and Hamer), 2696-2706

PML. See Promyelocytic leukemia nuclear protein

POD. See Promyelocytic leukemia oncogenic domain

Polar granules, role of Oskar protein- protein interactions in assembly (Breitwieser et al.), 2179- 2188

Polarity, cell, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777-793

Pole plasm, role of Oskar interaction with Vasa in formation (Breitwieser et al.), 2179-2188

pollux, role in tracheal function (Zhang et al.), 1108-1119

Poly(A) + RNA effect of stress on subcellular localiza-

tion in yeast (Saavedra et al.), 1608-1620

nuclear accumulation in Npl3p tem- perature-sensitive mutants (Lee et al.}, 1233-1246

Polyadenylation effects of CPSF interaction with the

U1 snRNP-A protein (Lutz et al.), 325-337

splice-site containing poly(A) enhancer (Lou et al.), 208-219

Polycomb genes, role in transcriptional repression (Kingston et al.), 905-920 Review

Polyomavirus, role of Src-family kinases in tumorigenesis (Lowell and Soriano), 1845-1857 Review

Polypyrimidine tract-binding protein, inhibition of polyadenylation cleavage (Lou et al.), 208-219

POMC gene. See Pro-opiomelanocortin gene

porcupine, encoding of putative transmembrane protein involved in Wingless processing (Kadowaki et al.), 3116-3128

Porins, role of SurA in outer membrane assembly in E. coli (Rouvi6re and Gross), 3170-3182

Position effect, telomeric effect on transcriptional silencing

(Maillet et al.), 1796-1811 role of Rapl protein (Marcand et al.),

1297-1309 Position-effect variegation, suppression

by transcriptional enhancers (Wakers et al.), 185-195

Potentiator, mutation in GALl 1 that al- lows GAL4 interaction (Farrell et al.), 2359-2367

POU domain proteins cooperative binding of Oct-1 POU sub-

domains {Klemm and Pabo), 27- 36

coupling of cell lineage asymmetry with unc-86 transcription (Bau- meister et al.), 1395-1410

effects of Tst-1/Oct-6/SCIP deletion in mice (Bermingham et al.), 1751-1762

sequence-specific DNA binding of B-cell coactivator OCA-B (Ce- pek et al.), 2079-2088

PP2A. See Protein phosphatase type 2A PP2C. See Protein phosphatase type 2C PPAR. See Peroxisome proliferation-ac-

tivated receptor PPCA. See Protective protein/cathepsin A pre-mRNA. See Messenger RNA, precur-

sors Pre-RCs. See Prereplicative complexes Preinitiation complex

NHP6A/B role in assembly in S. cerevisiae (Paull et al.), 2769-2781

UAF role in formation (Keys et al.), 887-903

Prereplicative complexes assembly at eukaryotic replication or-

igins (Diffley), 2819-2830 Re- view

promotion by Cdc6 during the cell cycle (Piatti et al.), 1516-1531

Prions de novo generation of infectivity (Tell-

ing et al.), 1736-1750 role of human Prp homolog HRH1 in

nuclear export (Ohno and Shimura), 997-1007

Programmed cell death. See also Apop- tosis


Bcl-x L and p53 in checkpoint control (Minn et al.), 2621-2631



grim role in Drosophila (Chen et al.}, 1773-1782


p53 levels and extent of tumor cell apoptotic response (Chen et al.), 2438-2451




XPB and XPD role in p53-dependent pathway (Wang et al.), 1219- 1232

Proliferation, cellular effects of erythropoietin receptor gene

inactivation (L ine t al.), 154- 164

inhibition through p21 elevation by C/EBPa (Timchenko et al.), 804-815

role of ATM in regulation (Xu and Bal- timore), 2401-2410

Prolyl isomerases. See Isomerase, prolyl

Promoter binding of Drosophila TFIID to down-

stream basal element (Burke and Kadonaga), 711-724

codirection of TFIIIB binding to tRNA genes by TBP and TFIIIC (Joazeiro et al.), 725-739

RNA polymerase ~ subunit binding in E. coli (Gaal et al.), 16-26

specificity, independent regulation of neighboring genes (Merli et al.), 1260-1270

Promoter/enhancer interaction, independent regulation of neighboring genes (Merli et al.), 1260- 1270

Promyelocytic leukemia nuclear protein, and adenovirus repli-

cation (Doucas et al.), 196-- 207

oncogenic domain, and adenovirus replication Doucas et al.), 196- 207

Pro-opiomelanocortin gene, transcriptional regulation by Ptxl (Lam- onerie et al.), 1284-1295

prospero, Rasl regulation during Droso- phila eye development {Kauff- mann et al.), 2167-2178

Proteases, role of Lon protease in cell-

cycle control of DNA methylation (Wright et al.), 1532- 1542

Proteasome protection of E2F-1 from degradation

pathway by Rb (Hofmann et al.), 2949-2959

regulation of cyclin E turnover by cdk2 (Clurman

et al.), 1979-1990 E2F degradation by Rb family pro-

teins and adenovirus transforming proteins (Hateboer et al.), 2960-2970

Protective protein/cathepsin A, interaction with human neuraminidase (Bonten et al.), 3156- 3169

Protein degradation

APC-dependent proteolysis of Pdslp (Cohen-Fix et al.), 3081-3093

protection of E2F-1 from ubiquitin- proteasome degradation pathway by Rb (Hofmann et al.), 2949-2959

regulation of E2F degradation by Rb family proteins and adenovirus transforming proteins (Hateboer et al.), 2960-2970

folding, role of SurA in E. cob (Rou- vihre and Gross), 3170-3182

import, inhibition following cellular stress in yeast (Saavedra et al.), 1608-1620

Protein kinase A, as a negative regulator of Hedgehog signaling (Ham- merschmidt et al.), 647-658

Protein kinase C, suppression of v-raf transformation by PKC-~ (Kieser et al.), 1455-1466

Protein kinases. See Kinases Protein kinases, stress activated

activation by HPK1 (Hu et al.), 2251- 2264


Protein phosphatase, ceramide-activated mediation of G~ arrest in Saccharomy-

ces cerevisiae (Nickels and Broach), 382-394

Protein phosphatase type 2A nutrient stimulation of Tap42 associ-

ation with PP2A (DiComo and Arndt), 1904-1916

regulation of Rasl-mediated signaling (Wassarman et al.), 272-278

Protein phosphatase type 2C, role of FEM-2 in C. elegans sex determination (Chin-Sang and Spence), 2314-2325

Protein phosphatases. See Phosphatases Protein stabilization, extension of p21

half-life by C/EBPa (Tim- chenko et al.), 804-815

Protein synthesis, ribosome jumping in

virus-infected and heat-shocked cells (Yueh and Schneider), 1557-1567

Protein-DNA interactions, cooperativity of the Oct-1 POU subdo- mains (Klemm and Pabo), 27- 36

Protein-protein interactions Digl and Dig2 as substrates of Kssl in

S. cerevisiae (Cook et al.), 2831- 2848

FEM-2 and FEM-3 in C. elegans sex determination (Chin-Sang and Spence), 2314-2325

function of the U2AF 35-kD subunit (Zuo and Maniatis), 1356-1368

glucose regulation of yeast SNF1 complex interactions (Jiang and Carlson), 3105-3115


with Oskar in Drosophila pole plasm formation (Breitwieser et al.), 2179-2188


PU.1 ternary complex formation with Pip (Brass et al.), 2335-2347

role of EVES motif in c-Myb regulation

(Dash et al.), 1858-1869 Rb interaction with C/EBPs in adi-

pocyte terminal differentiation (Chen et al.), 2794-2804

Sin in c-Src activation (Alexandropou- los and Baltimore), 1341-1355

specificity of LIM-LIM interactions (Arber and Caroni), 289-,300

SpoIIAB with CF in B. subtilis (Decatur and Losick), 2348-2358

stimulation of phosphatase activity in B. subtilis (Yang et al.), 2265- 2275

Proteins, tissue-specific conversion of aNAC to myotube-spe-

cific factor (Yotov and St-Ar- naud), 1763-1772


Prothymosin-a gene, specific activation by Myc (Desbarats et al.), 447-460

PrP genes. See Prions PTB. See Polypyrimidine tract binding

protein Ptxl, novel bicoid-related homeo box

factor (Lamonerie et al.), 1284- 1295

PU.1, ternary complex formation with Pip (Brass et al.), 2335-2347

pyp2, induction by Sty1 and Atfl in S. pombe (Wilkinson et al.), 2289- 2301


r7 photoreceptor. See also Photoreceptor cells

RAD9, parallel sensory branches for DNA damage signaling in S. cerevisiae (Navas et al.), 2632- 2643

RAD52, role of protein product homolog in RAD51-independent recombination in yeast (Bai and Sym- ington), 2025-2037

Rad53, regulation by Mecl-dependent protein phosphorylation (Sun et al.), 395--406

Radiation, ionizing, role of p53 in radiation-induced differentiation in scid mice (Bogue et al.), 553- 565

Raf comparison of KSR (Therrien et al.),

2684-2695 effect of PP2A on signaling (Wassar-

man et al.), 272-278 stimulation resulting in phosphoryla-

tion of HSF1 (Knauf et al.), 2782-2793

RAFT1 kinase domain, rapamycin-sensitive TOR function in yeast (Alarcon et al.), 279-288

RAG proteins. See Recombinase activating gene proteins

Ran/TC4 GTPase system, role in regulation of mRNA during stress in yeast (Saavedra et al.), 1608- 1620

Rap l protein, role in silencing at nontelomeric regions (Marcand et al.), 1297-1309

Rapamycin sensitivity role of Tot signaling in nutrient stim-

ulation of Tap42 association with PP2A (DiComo and Arndt), 1904-1916

TOR function in yeast (Alarcon et al.), 279-288

Rapid deletion, telomeric, novel mechanism for telomere size control in yeast (Li and Lustig), 1310- 1326

Ras aggressive tumorigenic behavior of

p21-deficient keratinocytes af- ter transformation (Missero et al.), 3065-3075

cooperation with TGF-[~ in regulation of tumor cell plasticity (Oft et al.), 2462-2477

cooperativity with KSR (Therrien et al.), 2684-2695

effect of PP2A on signaling (Wassar- man et al.), 272-278

Rasl regulation of prospero transcription during Drosophila eye development (Kauffmann et al.), 2167-2178

role of TFIIA in photoreceptor determination (Zeidler et al.), 50-59

Rasl signaling and transcription during development (Kauffmann et al.), 2167-2178

Ras pathway, Lozenge interaction to de- termine photoreceptor cell (Daga et al.), 1194-1205

Rb dephosphorylation during p53-depen-

dent cell cycle arrest induced by ribonucleotide depletion (Linke et al.), 934-947

differential effects of cdk2 and cdk3 on E2F function during G~ exit (Hofmann and Livingston), 851- 861

functional overlap of p107 in mice (Lee et al.), 1621-1632

protection of E2F-1 from ubiquitin- proteasome degradation pathway (Hofmann et al.), 2949- 2959

regulation of E2F degradation (Hateboer et al.l,

2960-2970 skeletal muscle-cell development in

mice (Zackenhaus et al.), 3051- 3064

related Drosophila gene RBF (Due t al.), 1206-1218

role in apoptosis (White), 1-15 Review of interaction with C/EBPs in adipo-

cyte terminal differentiation (Chen et al.), 2794-2804

Rb family regulation of E2F degradation by p107

and p130 (Hateboer et al.), 2960-2970

shared role of p107 and p130 in limb development in mice (Cobrinik et al.), 1633-1644

RBF, Drosophila Rb-related gene (Duet al.), 1206-1218

rDNA. See DNA, ribosomal RecA protein, preferred DNA pairing se-

quences (Tracy and Kowal- czykowski), 1890-1903

Receptor tyrosine kinases Breathless role in patterning cell mi-

gration and branching in Droso- phila (Lee et al.), 2912-2921

c-ros role in epithelial development (Sonnenberg-Riethmacher et al.), 1184-1193


Heartless role in Drosophila development (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017

regulation of Rasl-mediated signaling by PP2A in Sevenless pathway (Wassarman et al.), 272-278

TrkB and TrkC role in promoting neu-

ton survival (Minichello and Klein), 2849-2858

Vein role in Drosophila EGF pathway (Schnepp et al.), 2302-2313

Receptors, nuclear, in vivo mutagenesis of required HoxD complex regulatory element (G6rard et al.), 2326-2334

Recombinase activating gene proteins

activation of DNA damage checkpoint by V(D)J recombination (Guidos et al.), 2038-2054

role of RAG2 in T-cell receptor [3-chain gene rearrangement (Hoffman et al.), 948-962

in Xer site-specific recombination (Blakely and Sherratt), 762-773

Recombination cap-prevented, role in telomere main-

tenance (McEachern and Black- burn), 1822-1834

exon coconversion biases accompanying intron homing (Mueller et al.), 2158-2166

meiotic effects of ATM disruption in mice

(Xu et al.), 2411-2422 role of ATM (Hawley and Friend),

2383-2388 Review role in telomere maintenance

(McEachern and Blackburn), 1822-1834

role of Rad52 homolog in RAD51-independent process in yeast {Bai and Symington), 2025-2037

selection of preferred DNA pairing sequences by E. coli RecA protein (Tracy and Kowalczykowski), 1890-1903

site-specific determinants of Xer selectivity

(Blakely and Sherratt), 762-773 restriction of dif site activity in E.

coli (Cornet et al.), 1152-1161 V(D)!

activation of p53-dependent DNA damage checkpoint (Guidos et al.), 2038-2054

requirement of p53 for rescue in scid mice (Bogue et al.), 553-565

Regionalization, role of c-ros in epithelial development (Sonnenberg- Riethmacher et al.), 1184-1193

Regulation, negative, role of EVES motif in c-Myb regulation (Dash et al.), 1858-1869

rel/NFKB proteins activation of dorsal by Toll, tube, and


NFKB-mediated chromatin reconfiguration and transcriptional activation of HIV- 1 enhancer (Pazin et al.), 37-49

Replication. See also DNA replication


conjugating plasmids as preferred targets for Tn7 {Wolkow et al.), 2145-2157

determinants of late origin activation {Friedman et al.), 1595-1607

overexpression of Ruml and re-replication in fission yeast (Jallepalli and Kelly), 541-552


POD organization and adenoreplication (Doucas et al.), 196-207

promotion by Cdc6 during the cell cycle (Piatti et al.), 1516-1531

recombination-dependent, as a pathway for intron mobility (Muel- let et al.), 351-364


regulation and specification of eukaryotic origins (Diffley), 2819-2830 Review

Replication protein A, yeast domains with similarity to the E. coli SSB protomer (Philipova et al.), 2222-2233

Replicon model, of eukaryotic replication (Diffley), 2819-2830 Re- view

Repressed state, role of silencers in inheritance (Holmes and Broach), 1021-1032

Repression, transcriptional altered intracellular receptor activa-

tion properties (Start et al.), 1271-1283

CF2 role in EGF-R-activated dorsoventral patterning (Hsu et al.), 1411-1421

corepressor requirement for Drl (Mer- melstein et al.), 1033-1048

effects of telomere proximity and Sir protein concentration on silencing (Maillet et al.), 1796-1811

identification of KAP-1 as KRAB domain corepressor (Friedman et al.), 2067-2078


short-range repressors role in Droso- phila embryos (Gray and Levine), 700-710

silencers role in yeast {Holmes and Broach), 1021-1032

Repressor, maternal, titration of during Drosophila embryogenesis (Pritchard and Schubiger), 1131-1142

Resolvase, dif site insertions in E. coli (Kuempel et al.), 1162-1171; Corrigendum, 1709

Respiration, effects of Tst-1/Oct-6/SCIP

deletion in mice {Bermingham et al.), 1751-1762

Retina, dysplasia in p107-null mice (Lee et al.), 1621-1632

Retrotransposons integration of Ty5 into regions of si-

lent chromatin (Zou et al.), 634- 645

targeting of Tyl to upstream regions of RNA pol III-transcribed genes (Devine and Boeke), 620--633

Retroviruses, frequent provirus insertional mutagenesis in MMTV/ myc transgenic mice {Girard et al.), 1930-1944

Ribonucleoproteins, role of hrp45 in binding to exonic pre-mRNA and nucleocytoplasmic transport {Alzhanova-Ericsson et al.), 2881-2893

Ribosomal DNA. See DNA, ribosomal Ribosomal RNA. See RNA, ribosomal Ribosome jumping, in virus-infected and

heat shocked cells (Yueh and Schneider), 1557-1567

Ribosome shunting. See Ribosome jumping

Rice blast fungus, MAP kinase and cAMP regulation of M. grisea infection (Xu and Hamer), 2696-2706

RING finger proteins, identification of KAP-1 as KRAB domain corepressor (Friedman et al.), 2067- 2078

RING3, a novel nuclear kinase in human cells (Denis and Green), 261-271

RNA -binding proteins

HF-I role in rpoS translation (Muff- ler et al.), 1143-1151

SLBP role in processing histone pre-mRNA (Wang et al.), 3028- 3040

bulged, role in down-regulation of LIN-14 (Ha et al.), 3041-3050

export hrp45 role in accompanying pre-

mRNA to nuclear pores (Alzha- nova-Ericsson et al.), 2881-2893

Npl3p as mediator (Lee et al.), 1233- 1246

regulation during stress in yeast (Saavedra et al.), 1608-1620

RNA helicase-like protein HRH1 role (Ohno and Shimura), 997- 1007

helicase, role of RNA helicase-like protein HRH1 in nuclear export (Ohno and Shimura), 997-1007

import, anticodon as signal sequence for targeting tRNA to mitochondria (Rusconi and Cech), 2870-2880

localization, anticodon as signal se-

quence for tRNA import into mitochondria (Rusconi and Cech), 2870--2880

polymerase carboxy-terminal domain, NMR

analysis of novel DNA-binding domain (Gaal et al.), 16-26

DNA-binding determinants of the {~ subunit in E. coli (Gaal et al.), 16-26

findings presented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary

gene activation by Pol II holoenzyme recruitment (Farrell et al.), 2359-2367

Pol II general transcription factors (Orphanides et al.), 2657-2683 Review

role of TBP in Pol I transcription of rDNA in S. cerevisiae (Steffan et al.), 2551-2563

role of UAF in pol I preinitiation complex formation (Keys et al.), 887-903

targeting of Tyl integration to upstream regions of pol III-transcribed genes (Devine and Boeke), 620-633

processing SL1 RNA role in C. elegans embryo-

genesis (Ferguson et al.), 1543- 1556

3'--~5' exonuclease role in 5.8S RNA synthesis {Mitchell et al.), 502-513

ribosomal SL1 RNA role in C. elegans embryo-


3'---~5' exonuclease role in 5.8S RNA synthesis {Mitchell et al.), 502-513

RNA-protein interactions, role of the U2AF 35-kD subunit (Zuo and Maniatis), 1356-1368

RNPs. See Ribonucleoproteins RPA. See Replication protein A RRN5, role of protein product in RNA

pol I preinitiation complex formation {Keys et al.), 887-903

RRN9, role of protein product in RNA pol I preinitiation complex formation {Keys et al.), 887-903

RRNIO, role of protein product in RNA pol I preinitiation complex formation (Keys et al.), 887-903

rRNA. See RNA, ribosomal RRP4 gene, role of protein product in

5.8S RNA synthesis {Mitchell et al.), 502-513

RS domains, role in splicing (Manley and Tacke), 1569-1579 Review

Ruml, inhibition of Cdc2 kinase and interaction with Cdcl8 (Jallepalli and Kelly), 541-552


Runt, homologous domains found in Lozenge (Daga et al.), 1194- 1205

RXRB, effects of gene inactivation in mice (Kastner et al.), 80-92

S phase determinants of late origin activation

in yeast (Friedman et al.), 1595- 1607

regulation of onset by fission yeast ORC1 homolog orpl (Grallert and Nurse), 2644-2654

role of E2F and cyclin E in Drosophila (Duronio et al.), 2505-2513

timing of replication promotion by Cdc6 during the cell cycle (Pi- atti et al.), 1516-1531

truncation during the Drosophila endocycle (Lilly and Spradling), 2514-2526

Saccharomyces cerevisiae. See also Yeast, budding

activation of CUP1 in strains lacking SOD1 (Liu and Thiele), 592-603

APC-dependent degradation of Pdslp (Cohen-Fix et al.), 3081-3093

ceramide-activated protein phosphatase (Nickels and Broach), 382-394

CUS1 gene product role in spliceosome assembly (Wells et al.), 220-232

determinants of late origin activation (Friedman et al.), 1595-1607

DIG1 and DIG2 as two novel MAP kinase targets (Cook et al.), 2831- 2848

epigenetic effects on transcription caused by mutations in a nuclear actin-related protein (Jiang and Stillman), 604-619


function of Swp73 in Swi/Snf complex (Cairns et al.), 2131-2144

glucose regulation of SNF1 complex interactions (Jiang and Carlson), 3105-3115

histone amino-termini role in nucleosome assembly (Ling et al.), 686-699

identification of Mudl3p as homolog of CBP20 (Color et al.), 1699- 1708

in vivo function of yTAFn90 (Apone et al.), 2368-2380

interaction of Swel regulators with histone amino

termini (Ma et al.), 1327-1340 Tupl with histones H3 and H4 (Ed-

mondson et al.), 1247-1259

masked expression of copper transport gene by Ty2 (Knight et al.), 1917-1929

NHP6A/B role in transcriptional stimulation (Paull et al.), 2769-2781

Npl3p role in RNA export (Lee et al.}, 1233-1246

parallel sensory branches for DNA damage signaling (Navas et al.), 2632-2643

preferential integration of Ty5 into regions of silent chromatin (Zou et al.), 634-645

protein product homolog role in RAD51-independent recombination (Bai and Symington), 2025-2037

Rap l protein role in silencing at nontelomeric regions {Marcand et al.), 1297-1309

redundancy of MSH3 and MSH6 in mismatch repair (Marsischky et al.I, 407-420

regions of RPA subunits with similarity to E. coli SSB protomer (Phil- ipova et al.), 2222-2233

regulation and specification of replication origins (Diffley), 2819- 2830 Review

regulation of mRNA export during stress (Saavedra et al.), 1608- 1620

silencers role in inheritance of repression (Holmes and Broach), 1021-1032

single-stranded telomere end-binding protein properties of Est 1 (Virta- Pearlman et al.), 3094-3104


targeting of retrotransposon Tyl to upstream regions of RNA pol II- transcribed genes (Devine and Boekel, 620-633

TBP role in rDNA transcription (Stef- fan et al.), 2551-2563

3'-+ 5' exonuclease role in 5.8S RNA synthesis (Mitchell et al.), 502- 513

Tor signaling role in nutrient stimulation of Tap42 association with PP2A (DiComo and Arndt), 1904-1916

U2 snRNP proteins role in spliceosome assembly (Gozani et al.), 233-243

UAF role in RNA pol I preinitiation complex formation (Keys et al.), 887-903

Sadl, regulation by Mecl-dependent protein phosphorylation (Sun et al.), 395M06

SAP 145 binding upstream of branchpoint se-

quence (Gozani et al.), 233-243

homology of Saccharomyces cerevisiae CUS1 gene product (Wells et al.), 220-232

SAPIa, inability of Pax-5 to recruit to a B-cell-specific promoter (Fitz- simmons et al.), 2198-2211

SAPKs. See Protein kinases, stress-activated

Satellite cells, role of MyoD in myogenic stem cell function (Megeney et al.), 1173-1183

SBF. See SCB-binding factor SC35, role in splicing (Manley and

Tacke), 1569-1579 Review SCB-binding factor, cell-cycle regulation

(Koch et al.}, 129-141 Schizosaccharomyces pombe. See also

Yeast, fission d m f l / m i d l role in positioning of divi-

sion septum (Sohrmann et al.), 2707-2719

regulation of Atfl by Spcl in response to stress


Atfl by stress-activated kinase Styl (Wilkinson et al.), 2289-2301

S-phase onset by ORC1 homolog orpl (Grallert and Nurse), 2644- 2654

Rum l inhibition of Cdc2 kinase and interaction with Cdcl8 (Jalle- palli and Kelly), 541-552

Schwann cells, effects of Tst-1/Oct-6/ SCIP deletion in mice (Berming- ham et al.), 1751-1762

SCID activation of DNA damage checkpoint

by V(D)J recombination in lym- phocyte precursors (Guidos et al.), 2038-2054

cooperativity with p53 in tumorigenesis (Nacht et al.), 2055-2066

mice (scid}, role of p53 in radiation-induced differentiation and rescue of V(D)J rearrangement (Bogue et al.), 553-565

SCIP, effects of gene deletion in mice (Bermingham et al.), 1751-1762

Scr. See Sex combs reduced Scrapie, de novo generation of prion in-

fectivity in mice (Telling et al.), 1736-1750

SDI- 1. See p21 Secondary structure, mRNA, role of HF-I

in rpoS translation (Muffler et al.), 1143-1151

Segment-polarity genes, role of porcupine in Wingless processing (Ka- dowaki et al.), 3116--3128

Segmentation Fab-7

attenuation of enhancer-promoter interactions in Drosophila (Zhou et al.), 3195-3201

as chromatin domain boundary in



role of bagpipe and serpent in Droso- phila (Azpiazu et al.), 3183- 3194

Selectivity, determinants in Xer site-specific recombination (Blakely and Sherratt), 762-773

sere-4, role in neuronal and mesodermal development (Basson and Hor- vitz), 1953-1965

Sensory organs. See Organs, sensory Septation, role of SpoIIE in asymmetric

cell division (Feucht et al.), 794- 8O3

Septins, role of Axl2p in bud-site selection in yeast (Roemer et al.), 777-793

serpent, role in segmentation and specification of Drosophila mesoderm (Azpiazu et al.), 3183-3194

Serrate, complementarity of Delta in Drosophila wing development (Doherty et at.), 421-434

Sertoli cells, accumulation of lipids in RXR~-deficient mice (Kastner et al.), 80-92

Seven-transmembrane proteins, encoded by lin-I7 in C. elegans (Sawa et al.), 2189-2197

Sevenless regulation of prospero through activa-

tion Rasl/MAP kinase pathway in R7 photoreceptors (Kauff- mann et al.), 2167-2178

role of PP2A in signaling pathway (Wassarman et al.), 272-278

seven-up, negative regulation by Droso- phila Lozenge (Daga et at.), 1194-1205

Sex combs reduced, control of trachealess expression in the Droso- phila salivary duct (Isaac and Andrew), 103-117

Sex determination assembly of specific SR protein com-

plexes at the doublesex splicing enhancer (Lynch and Maniatis), 2089-2101

role of FEM-2 in C. elegans (Chin-Sang and Spence), 2314-2325

Sexual differentiation. See Differentia- tion, sexual

Sey phenotype. See Small eye phenotype SF2. See ASF/SF2 SH2 domain, in novel pl3OC~-related

protein Sin (Alexandropoulos and Baltimore), 1341-1355

SH3 domain, role in interaction of c-Src with Sin (Alexandropoulos and Baltimore), 1341-1355

Shc, role of inositol phosphatases in signal transduction (Majerus), 1051-1053 Minireview

short gastrulation, prevention of Dpp autoactivation and suppression of

neurogenesis (Biehs et al.), 2922-2934

shotgun, as encoding Drosophila E-cadherin (Uemura et al.), 659-671; (Tepass et al.), 672-685

Shuttling, of Npl3p between cytoplasm and nucleus in yeast (Lee et al.), 1233-1246

Sialidosis, role of mutant human neuraminidase gene (Bonten et al.), 3156-,3169

~-factor HF-I role in rpoS translation (Muffler

et al.), 1143-1151 interaction of SpoIIAB with (r F in B.

subtilis (Decatur and Losick), 2348-2358

regulation of sigma B by stress response signaling in B. subtitis (Yang et al.), 2265-2275

release of cr ~ by SpolIE phosphorylation of SpoIAA-P (Feucht et al.), 794-803

Signal sequence, role of anticodon for tRNA import into mitochondria (Rusconi and Cech), 2870- 2880

Signal transduction activation of

dorsal by Toll, tube, and pelle (Nor- ris and Manley), 862-872

JNK/SAPK pathway by HPK1 (Hu et al.), 2251-2264

analysis of residues important for Torso signaling (Cleghon et al.), 566-577

~-catenin role in embryogenesis (Mil- ler and Moon), 2527-2539 Re- view

characterization of a novel nuclear kinase in human cells (Denis and Green), 261-271

conserved signaling through ceramide- activatcd protein phosphatase in Saccharomyces cerevisiae (Nickels and Broach), 382-394

Delta and Serrate as compartment-specific signals in the wing disc (Doherty et al.), 421-434

DIG1 and DIG2 as two novel MAP kinase targets in S. cerevisiae (Cook et al.), 2831-2848

FEM-2 phosphatase role in C. elegans sex determination (Chin-Sang and Spence), 2314-2325

function of human TOR homolog RAFT1 kinase (Alarcon et al.), 279-288

inositol phosphatases role (Majerus), 1051-1053 Minireview

JNK pathway mediating morphogenesis and an immune response in Drosophila (Sluss et al.), 2745- 2758; (Riesgo-Escovar et al.), 2759-2768

MAP kinase and cAMP regulation of

rice blast fungus M. grisea infection (Xu and Hamer), 2696- 2706

MIS pathway role in mammalian sexual differentiation (Mishina et al.), 2577-2587

p150 ship and Fms signal transduction (Lioubin et al.), 1084-1095


participation of Madr2 in the activin pathway (Baker and Harland), 1880-t889

regulation of Atfl by Spcl in S. pombe (Shiozaki

and Russell), 2276-2288 Atfl by Styl in S. pombe (Wilkinson

et al.), 2289-2301 developmental pathways by ERK2

in Dictyostelium discoideum (Gaskins et al.), 118-128


in response to stress in B. subtilis (Yang et al.), 2265-2275

role in MAPK signaling pathway (Therrien et al.), 2684-2695

tamou role in Drosophila development (Takahisa et al.), 1783- 1795

Signaling ~3-catenin and Xgsk-3 role in Xenopus

(Yost et al.), 1443-1454 CF2 role in EGF-R-activated dorsoven-


compartment-specific, role of Delta in Drosophila wing development (Doherty et al.), 421-434

effects of erythropoietin receptor gene inactivation (Lin et al.), 154- 164

Heartless role in Drosophila development (Beiman et al.), 2993- 3002; (Gisselbrecht et al.), 3003-3017

intercellular branched C-factor signaling path-

way in Myxococcus (Sogaard- Andersen et al.), 740-754

induction of patched by hedgehog in mice (Goodrich et al.), 301-312

midline, PKA regulation of Hedgehog signaling in vertebrates (Ham- merschmidt et al.), 647-658

Silencers, transcriptional, preferential integration of Ty5 into regions of silent chromatin (Zou et al.), 634-645

Silencing and chromatin structure (Kingston et

al.), 905-920 Review Rap l protein role at nontelomeric re-

gions (Marcand et al.), 1297- 1309


silencers role in inheritance of repression in yeast (Holmes and Broach), 1021-1032

suppression of position-effect variegation by transcriptional enhancers (Wakers et al.), 185- 195

telomeres role {Maillet et al.}, 1796- 1811

of X-linked genes in response to DNA hypomethylation (Panning and Jaenisch), 1991-2002

Sin protein, role in c-Src activation (A1- exandropoulos and Baltimore), 1341-1355

SIN4, incomplete penetrance of transcriptional defect suppression in mutant yeast strains (Jiang and Stillman), 604-619

Sina, rote in up-regulation of prospero transcription during Drosophila eye development {Kauffmann et al.), 2167-2178

Single-stranded DNA-binding protein properties of Estl (Virta-Pearlman et

al.), 3094-3104 similarity of yeast RPA to E. coli SSB

protomer (Philipova et al.), 2222-2233

Sir proteins and chromatin structure (Kingston et

al.), 905-920 Review effect of protein concentration on si-

lencing (Maillet et al.), 1796- 1811

increased rate of telomeric rapid deletion caused by Sir3p mutations (Li and Lustig), 1310-1326

sequestration at telomeres by Rap 1 protein (Marcand et al.), 1297-1309

SIT4 association of protein product with

Tap42 (DiComo and Amdt), 1904-1916

as encoding the catalytic subunit of ceramide-activated protein phosphatase in S. cerevisiae (Nickels and Broach}, 382-394

Size control, telomeric, novel mechanism in yeast (Li and Lustig), 1310-1326

Skin, absence of plectin in MD-EBS pa- tients (McLean et al.), 1724- 1735

SL RNA. See Spliced leader RNA SL1 RNA, role of in C. elegans embryo-


SL2 RNA, substitution for SL1 RNA in C. elegans embryogenesis (Fer- guson et al.), 1543-1556

SLBP. See Stem-loop binding protein Small eye phenotype, caused by muta-

tions in mouse Pax6 {Quinn et al.), 435--446

Small lung cell carcinoma, in Rb +/-

mice (Nikitin and Lee), 1870- 1879

Small nuclear RNA CUS1 as suppressor of U2 snRNA

cold-sensitive mutations (Wells et al.), 220-232

effects of U I snRNA on 5' splice site selection {Hwang and Cohen), 338-350

redundant interactions between U2 and U6 snRNAs during splicing (Field and Friesen), 489-501

U 1 snRNA role in 5' splice site selection {Hwang and Cohen), 338-350

smaug protein, translational repression of unlocalized nanos mRNA {Smibert et al.l, 2600-2609

Snail, as transcriptional repressor (Gray and Levine), 700-710

SNF1, glucose regulation of protein-protein interactions (Jiang and Carlson), 3105-3115

snRNA. See Small nuclear RNA snRNP protein complexes, role in spli-

ceosome assembly (Gozani et al.), 233-243

snRNPs, and activation of polyadenylation by intron enhancer (Lou et al.), 208-219

Somites, role of BMPs in patterning (Hogan), 1580--1594 Review

Somitogenesis, caudal, role of mouse Wnt-3a (Greco et al.), 313-324

Spa2, AXL2 as high copy suppressor in spa2~ cdclO-lO mutant strains (Roemer et al.), 777-793

Spcl, regulation of Atfl in S. pombe (Shiozaki and Russell), 2276- 2288

Spermatogenesis defects in ATM-deficient mice (Xu et

al. }, 2411-2422 effects of

Bmp8b inactivation in mice (Zhao et al.), 1657-1669

RXR~3 inactivation in mice (Kastner et al.), 80-92

Spkl, regulation by Mecl-dependent protein phosphorylation {Sun et al.), 395-406

Splice site, 5', role of CBC in facilitating UlsnRNP association (Lewis et al.), 1683-1698

Spliced leader RNA, role of SL1 RNA in C. elegans embryogenesis (Fer- guson et al.), 1543-1556

Spliceosomal complex A, role of U2 snRNP proteins in assembly (Gozani et al.), 233-243

Spliceosome CUS1 role gene product in assembly

(Wells et al.), 220-232 RNA helicase-like protein HRH1 role

in facilitating release of spliced mRNA (Ohno and Shimura), 997-1007

U2 snRNP proteins role in assembly(Gozani et al.), 233-243

Splicing ASF/SF2 role in cell viability (Wang et

al.), 2588-2599 assembly of specific SR protein com-

plexes at the doublesex enhancer (Lynch and Maniatis), 2089-2101


differential, conversion of oLNAC to myotube-specific factor by in- clusion of proline-rich exon (Yotov and St-Arnaud), 1763- 1772

effects of U1 snRNA on 5' splice site selection (Hwang and Cohen), 338-350

enhancers, interactions with SR proteins (Manley and Tacke), 1569-1579 Review

function of the U2AF 35-kD subunit (Zuo and Maniatis), 1356-1368

HRH1 role in facilitating release of spliced mRNA from the spliceosome (Ohno and Shimura), 997- 1007

hrp45 role in binding to exonic pre- mRNA and nucleocytoplasmic transport (Alzhanova-Ericsson et al.), 2881-2893

Mudl3p as yeast homolog of CBP20 (Colot et al.), 1699-1708

nuclear cap-binding complex role in pre-mRNA recognition (Lewis et al.), 1683-1698

redundant interactions between U2 and U6 snRNAs (Field and Frie- sen), 489-501

splice-site containing poly[A) enhancer (Lou et al.), 208-219

SR proteins (Manley and Tacke), 1569-1579 Review

U2 snRNP proteins in spliceosome assembly (Gozani et al.), 233- 243

SpoA, dependence of switch to bipolar localization of FtsZ in B. subtilis (Levin and Losick), 478-488

SpoIIAB, interaction of SpoIIAB with O "F

in B. subti l is (Decatur and Losick}, 2348-2358

Sporulation bifunctionality of SpoIIE in asymmet-

ric cell division and cell-specific transcription (Feucht et al.), 794--803

and bipolar localization of FtsZ in B. subti l is (Levin and Losick), 478--488

role of extracellular peptide in B. subtilis (Solomon et al.), 2014-- 2024

SR proteins


ASF/SF2 role in cell viability (Wang et al.), 2588-2599

assembly of specific complexes at the doublesex splicing enhancer (Lynch- and Maniatis), 2089- 2101

hrp45 role in binding to exonic pre- mRNA and nucleocytoplasmic transport (Alzhanova-Ericsson et al.), 2881-2893

role in splicing (Manley and Tacke), 1569-1579 Review

U2AF 35-kD subunit in splicing (Zuo and Maniatis), 1356-1368

SRB proteins, findings presented at Cold Spring Harbor meeting (McKnight), 367-381 Meeting commentary

Src, role of Sin in c-Src activation (Alex- andropoulos and Baltimore), 1341-1355

SREBP 1, role in adipocyte differentiation (Kim and Spiegelman), 1096- 1107

SREBPs. See Sterol regulatory element binding proteins

SSA1, nucleocytoplasmic export of mRNA during stress in yeast (Saavedra et al.}, 1608-1620

SSA4, nucleocytoplasmic export of mRNA during stress in yeast (Saavedra et al.), 1608-1620

SSB. See Single-stranded DNA-binding protein

SSN6/TUP1 and chrornatin structure (Kingston et

al.), 905-920 Review interaction of Tupl with histones H3

and H4 (Edmondson et al.), 1247-1259

Start, activation of bound SBF during (Koch et al.), 129-141

Staufen, role of interaction with Oskar in Drosophila pole plasm formation (Breitwieser et al.}, 2179-2188

Stem-loop binding protein, role in processing histone pre-mRNA (Wang et al.), 3028-3040

Sterility, male, in RXR[~-deficient mice (Kastner et al.), 80-92

Sterol regulatory element binding proteins, mediation of transcriptional activity by CBP (Oliner et al.), 2903-2911

Stress response regulation of Atfl by Spcl in S. pombe



serine kinases and phosphatases in B. subtilis (Yang et al.), 2265-2275

Styl, regulation of Atfl in S. pornbe (Wilkinson et al.), 2289-2301

Substrate specificities, of CED-3/ICE-

like proteases (Xue et al.), 1073- 1083

SucI/Cksl proteins, role of Xenopus homolog Xe-p9 in cell cycle control (Patra and Dunphy), 1503- 1515

Superoxide dismutase, activation of CUP1 in yeast lacking SOD1 (Liu and Thiele), 592-603

SurA, role in outer membrane porin assembly in E. coli (Rouvihre and Gross), 3170-3182

SV40 enhancer, in the study of position-ef-

fect variegation (Wakers et al.), 185-195

large T antigen release of active E2F in presence of

dominant-negative cdk2 (Hof- mann and Livingston), 851-861

TAF-like function (Damania and A1- wine), 1369-1381

Swel kinase, interaction of regulators with histone amino termini (Ma et al.), 1327-1340

SWI/SNF complex function of Swp73 component in yeast

(Cairns et al.), 2131-2144 identification of mammalian counter-

parts (Wang eta!.), 2117-2130 role in activator-dependent release of

transcriptional pausing (Brown et al.}, 1479-1490

role in restructuring chromatin (Kings- ton et al.), 905-920 Review

swirl, role in zebrafish development (Hammerschmidt et al.1, 2452- 2461

Swp73p, function in yeast Swi/Snf complex (Cairns et al.), 2131-2144

Synthesis-dependent strand annealing, role in intron mobility (Mueller et al.), 351-364

Synthetic lethality, for isolating histone amino termini-interacting proteins (Ma et al.), 1327-1340

T

T antigen. See SV40 large T antigen T cells

cooperativity of p53 and SCID in lymphomagenesis (Nacht et al.1, 2055-2066

rearrangement of Notch1 in mouse thymomas (Girard et al.), 1930- 1944

regulation of bcI-2 by domnant interfering Myb (Taylor et al.), 2732- 2744

T-cell receptor, coincident regulation of cell cycle and clonality during development (Hoffman et al.), 948-962

T/EBP. See Thyroid-specific enhancer- binding factor

T4 phage, intron mobility (Mueller et al.), 351-364

TAFs. See TATA-box-binding protein- associated factors

Tail bud, role of mouse Wnt-3a in formation (Greco et al.), 313-324

tamou, Drosophila homolog of ZO-1 (Takahisa et al.), 1783-1795

TANK, induction of NF-KB (Cheng and Baltimore), 963-973

Tap42, nutrient stimulation of Tap42 association with PP2A (DiComo and Arndt), 1904-1916

Target selection, preference of Tn7 for conjugating plasmids {Wolkow et al.), 2145-2157

Targeting, of Tyl integration to upstream regions of RNA pol III- transcribed genes (Devine and Boeke), 620-633

TATA box assembly of the TFIID-TFIIA complex

(Chi and Carey), 2540-2550 role of CIF as cofactor for TFIID-

dependent initiator function {Kaufmann et al.), 873-886

TATA-box-binding protein functional epitopes for Pol II transcrip-

tion (Bryant et al.), 2491-2504 role in

binding of Drosophila TFIID to downstream basai promoter element (Burke and Kadonaga}, 711-724

directing TFIIIB binding to tRNA genes (Joazeiro et al.), 725- 739

Pol II transcription (Orphanides et al.), 2657-2683 Review

rDNA transcription in S. cerevisiae (Steffan et al.1, 2551-2563

TATA-box~ protein-associated factors

in vivo function of yeast TAFn90 (Apone et al.), 2368-2380

role in binding of Drosophila TFIID to down-

stream basal promoter element (Burke and Kadonaga), 711-724

inhibition of activator-dependent transcription (Segil et al.), 2389- 2400

Pol II transcription (Orphanides et al.), 2657-2683 Review

role of CIF as cofactor for TFIID- dependent initiator function (Kaufmann et al.), 873-886

similar function of SV40 large T antigen (Damania and Alwine), 1369-1381

TATA-less genes, codirection of TFIIIB binding to tRNA genes by TBP and TFIIIC (Joazeiro et al.), 725- 739

TBP. See TATA-box-binding protein Tcl /mar iner family, in vitro transposi-


tion of Tcl in C. elegans (Vos et al.), 755-761

Telomeres preferential integration of Ty5 into re-

gions of silent chromatin (Zou et al.), 634-645

role in silencing (Maillet et al.), 1796- 1811

role of cap-prevented recombination in maintenance (McEachern and Blackburn), 1822-1834

single-stranded telomere end-binding protein properties of Est 1 {Virta- Pearlman et al.), 3094-3104

size control in yeast (Li and Lustig), 1310-1326

Telorneric position effect. See Position effect, telomeric

Telomeric rapid deletion. See Rapid deletion, telomeric

TER1, effect of deletion in Kluyveromy- ces lactis (McEachern and Blackburn), 1822-1834

Testis degeneration caused by Bmp8b inacti-

vation in mice (Zhao et al.), 1657-1669

role of MIS in mammalian sexual differentiation (Mishina et al.), 2577-2587

Tetrahymena, anticodon as signal sequence for tRNA import into mitochondria (Rusconi and Cech), 2870-2880

TFC4, and flexible alignments between TFIIIB and TFIIIC (Joazeiro et al.), 725-739

TFE-3, comparison to Myc in gene activation (Desbarats et al.), 447- 460

TFIIA functional TBP epitopes for Pol II tran-

scription (Bryant et al.), 2491- 2504

role in Pol II transcription (Orphanides et

al.), 2657-2683 Review Ras-mediated photoreceptor deter-

mination (Zeidler et al.), 50-59 role of complex formation with TFIID

in gene activation (Chi and Carey), 2540-2550

TFIIB findings presented at Cold Spring Har-

bor meeting (McKnight), 367- 381 Meeting commentary


TFIID binding to downstream basal promoter

element in Drosophila (Burke and Kadonaga), 711-724

CIF role as cofactor for initiator function (Kaufmann et al.), 873- 886

complex formation role with TFIIA in

gene activation (Chi and Carey), 2540--2550


functional TBP epitopes for Pol II transcription (Bryant et al.), 2491- 2504

inhibition of activator-dependent transcription (Segil et al.}, 2389- 2400


TAF-like function for SV40 large T antigen (Damania and Alwine), 1369-1381

TFIIE, role in Pol II transcription (Or- phanides et al.), 2657-2683 Re- view

TFIIH in Pol II transcription (Orphanides et

al.), 2657-2683 Review role of XPB and XPD in p53-dependent

apoptosis (Wang et al.), 1219- 1232

TFIIIB, codirection of binding to tRNA genes by TBP and TFIIIC (Joazeiro et al.), 725-739

TFIIIC, role in directing TFIIIB binding to tRNA genes (Joazeiro et al.), 725-739

TGF-~. See Transforming growth factor

TGF-[3. See Transforming growth factor 13 family

Thymocytes coincident regulation of cell cycle and

clonality during T-cell receptor development (Hoffman et al.), 948-962

p53 rescue of V(D)J rearrangement in scid mice (Bogue et al.), 553- 565

Thyroid-specific enhancer-binding factor, role of in organogenesis (Kimura et al.), 60--69

Tissue specificity conversion of aNAC to myotube-spe-

cific factor (Yotov and St-Ar- naud), 1763-1772

effect of liver-specific p21 overexpression in transgenic mice (Wu et al.), 245-260


PU. 1 ternary complex formation with lymphoid-restricted IRF Pip (Brass et al.), 2335-2347


Tn7, conjugating plasmids as preferred targets (Wolkow et al.), 2145- 2157

TNFR. See Tumor necrosis factor receptor

Toll receptor, functional interactions with pelle kinase and tube (Nor- ris and Manley), 862-872

TOP1, role in mitotic chromosome condensation in S. cerevisiae (Castafio et al.), 2564-2576

Topoisomerases, role in chromosome condensation in S. cerevisiae (Castafio et al.), 2564-2576

Tor proteins rapamycin-sensitive function in yeast

(Alarcon et al.), 279-288 role in stimulation of Tap42 associa-

tion with PP2A {DiComo and Arndt), 1904-1916

torpedo/DER signaling system, role in polarization of body axes during Drosophila oogenesis (Ray and Schtipbach), 1711-1723 Review

Torso, analysis of key residues for signaling (Cleghon et al.), 566-577

TPD3, as encoding the regulatory subunit of ceramide-activated protein phosphatase in S. cerevisiae (Nickels and Broach), 382- 394

Trachea expression of bHLH-PAS protein by

trachealess in Drosophila (Wilk et al.), 93-102

role of Breathless in patterning cell migration and branching in Droso- phila (Lee et al.), 2912-2921

trachealess as encoding bHLH-PAS protein (Wilk

et al.), 93-102 role in embryonic tube formation

(Isaac and Andrew), 103-117 TRAF family, TRAF2 as TANK co-in-

ducer of NF-KB activation (Cheng and Baltimore), 963-973

trans-splicing, role of SL1 RNA in C. elegans embryogenesis (Ferguson et al.), 1543-1556

Transcription activation of

dorsal by Toll, tube, and pelle (Nor- ris and Manley), 862-872

metallothionein by oxidative stress via HSF (Liu and Thiele), 592- 603

activator-dependent release of transcriptional pausing (Brown et al.), 1479-1490

altered intracellular receptor activation (Starret al.), 1271-1283

basal machinery binding of Drosophila TFIID to

downstream basal promoter element (Burke and Kadonaga), 711-724

codirection of TFIIIB binding to tRNA genes by TBP and TFIIIC (Joazeiro et al.), 725-739


corepressor requirement for Drl (Mermelstein et al.), 1033- 1048

functional TBP epitopes for Pol II transcription (Bryant et a].), 2491-2504

inhibit ion of activator-dependent transcription (Segil et al.), 2389- 2400

role in Pol II transcription (Or- phanides et al.), 2657-2683 Re- view

role of CIF as cofactor for TFIID-depen-

dent initiator function (Kauf- mann et al.}, 873-886

TFIIA in Ras-mediated photoreceptor determinat ion (Zeidler et al.), 50--59

TFIIA-TFIID complex formation in gene activation (Chi and Carey), 2540--2550

TAF-like function for SV40 large T antigen (Damania and Alwine), 1369-1381

binding of Drosophila TFIID to downstream basal promoter element (Burke and Kadonaga), 711-724

CBP as a coactivator of c-Myb (Dai et al.), 528-540

cell-specific, role of SpoIIE in regulating ~-factor in B. subtilis (Feucht et al.), 794-803

codirection of TFIIIB binding to tRNA genes by TBP and TFIIIC {Joazeiro et al.), 725-739

conversion of ~NAC to myotube-specific transcription factor (Yotov and St-Arnaud), 1763-1772

corepressor requirement for Drl-mediated repression (Mermelstein et al.), 1033-1048

coupling of cell lineage asymmetry with unc-86 transcription (Baumeister et al.), 1395-1410

effect of enhancers on position-effect variegation (Wakers et al.), 185- 195

epigenetic effects in yeast caused by mutat ions in nuclear actin-related protein (Jiang and Still- man), 604-619

factors activation of dorsal by Toll, tube and


bHLH-PAS protein as inducer of Drosophila tracheal cell fates (Wilk et al.), 93-102

bipolar localization of FtsZ in B. subtilis (Levin and Losick), 478-488

CBP as a coactivator of c-Myb (Dai et al.), 528-540

conversion of RNAC to myotube-



gene activation by GAL4-GALl lP interaction (Farrell et al.), 2359- 2367

identification of mammalian SWI/ SNF complexes (Wang et al.), 2117-2130

inhibition of ATF-2 activation by its DNA-binding domain {Li and Green), 517-527

interaction of SpoIIAB with cr F (De- catur and Losick), 2348-2358

KrGppel and snail as transcriptional repressors (Gray and Levine), 700-710


novel bicoid-related homeo box factor Ptxl (Lamonerie et al.), 1284-1295

nuclear colocalization of AP- ETALA3 and PISTILLATA (McGonigle et al.), 1812-1821

Pip autoinhibition and ternary complex formation with PU. 1 (Brass et al.), 2335-2347

regulation of Atfl by Spcl in S. pombe


Atfl by Styl in S. pombe (Wilkin- son et al.), 2289-2301

epithelial growth and differentiation by nude locus product Whn (Brissette et al.), 2212-2221

HSF1 by phosphorylation (Knauf et al.), 2782-2793

kidney development by BF-2 (Ha- tini et al.), 1467-1478

relationship of trachea Jess gene product to Drosophila single- minded protein (Isaac and An- drew), 103-117

relationship of trachealess gene product to human hypoxia-in- ducible factor- 1~ (Isaac and An- drew), 103-117

RNA Pol II general factors (Or- phanides et al.), 2657-2683 Re- view

role of ADD1/SREBP1 in adipocyte dif-

ferentiation (Kim and Spiegel- man), 1096-1107


EKLF in human 6-globin gene competition (Wijgerde et al.), 2894-2902

Rb interaction with C/EBPs in ad-

ipocyte terminal differentiation (Chen et al.), 2794-2804

UAF in RNA pol I preinitiation complex formation (Keys et al.), 887-903

use of HSF1 activation domain to readthrough transcriptional pausing (Brown et al.), 1479- 1490



functional TBP epitopes for Pol II activity (Bryant et al.), 2491- 2504

gene activation by GAL4-GAL11P interaction (Farrell et al.), 2359- 2367

identification of mammal ian SWI/ SNF complexes (Wang et al.), 2117-2130

in vitro, reconsti tution of initiator activity (Kaufmann et al.), 873- 886

in vivo function of yeast TAFn90 (Apone et al.), 2368-2380

independent regulation of neighboring genes (Merli et al.), 1260-1270


localization of TFIID and inhibit ion of activation {Segil et al.), 2389- 2400

masked expression of yeast copper transport gene by Ty2 (Knight et al.), 1917-1929


mediation of SREBP activity by CBP (Oliner et al.), 2903-2911

RNA Pol II general factors (Orphanides et al.), 2657-2683 Review

role of chromatin in activation and repres-

sion (Kingston et al.), 905-920 Review

CIF as cofactor for TFIID-dependent initiator function (Kaufmann et al.), 873-886

EKLF in human ~-globin gene competition {Wijgerde et al.), 2894- 2902

EVES motif in c-Myb regulation (Dash et al.), 1858-1869

NF-KB in recrui tment of RNA polymerase II to the HIV-1 promoter (Pazin et al.), 37-49

NURF in activation (Kingston et al.), 905-920 Review

p53 (Ko and Prives), 1054-1072 Re- view


S. cerevisiae NHP6A/B in stimulation (Paull et al.), 2769-2781

short-range repressors in Drosophila embryos (Gray and Levine), 700--710

silencers in inheritance of repression in yeast (Holmes and Broach), 1021-1032

SWI/SNF in activation (Kingston et al.}, 905-920 Review

TBP in rDNA expression in S. cerevisiae (Steffan et al.), 2551-2563

UAF in RNA pol I preinitiation complex formation (Keys et al.), 887-903


TAF-like function for SV40 large T antigen (Damania and Alwine), 1369-1381

targeting of retrotransposon Ty 1 to upstream regions of RNA pol II- transcribed genes (Devine and Boeke), 620--633

Transfer RNA, anticodon as signal sequence for import into mitochondria (Rusconi and Cech), 2870-2880

Transformation malignant, in Rb +/- mice {Nikitin

and Lee), 1870-1879 suppression by PKC-~ (Kieser et al.),

1455-1466 Transformer proteins, role in recruiting

SR proteins to the doublesex splicing enhancer (Lynch and Maniatis), 2089-2101

Transforming growth factor a, gene inactivation as compared to keratinocyte growth factor gene inactivation (Guo et al.), 165- 175

Transforming growth factor [~ family regulation of tumor cell plasticity by

TGF-[~ (Oft et al.), 2462-2477 role of MIS in mammalian sexual dif-

ferentiation (Mishina et al.), 2577-2587

sog prevention of Dpp autoactivation and suppression of neurogenesis (Biehs et al.), 2922-2934

Transgenesis, Tcl as potential vector (Vos et al.), 755-761

Transgenic flys for studying binding of TFIID to down-

stream basal promoter element {Burke and Kadonaga), 711-724

for studying the regulation of Rasl- mediated signaling by PP2A (Wassarman et al.), 272-278

Transgenic mice abnormal kidney development in ani-

mals expressing wild-type p53 (Godley et al.l, 836-850

de novo generation of prion infectivity (Telling et al.), 1736--1750

in study of tissue-specific inactivation of p53 tumor suppression (Bow- man et al.], 826-835

Translation down-regulation of LIN-14 mediated

by 3' UTR (Ha et al.), 3041- 3050

initiation, ribosome jumping in virus- infected and heat shocked cells {Yueh and Schneider), 1557- 1567

regulation of nanos mRNA (Daha- nukar and Wharton), 261 0-2620

repression of unlocalized nanos mRNA (Smibert et al.), 2600- 2609

Transmembrane proteins. See also Seven-transmembrane proteins

as encoded by Drosophila porcupine (Kadowaki et al.), 3116-3128

possible structure of the mouse patched gene product (Goodrich et al.), 301-312

Transport, nucleocytoplasmic, regulation of mRNA export during stress in yeast (Saavedra et al.), 1608-1620

Transposition of C. elegans Tcl in vitro (Vos et al.),

755-761 conjugating plasmids as preferred tar-

gets for Tn7 (Wolkow et al.), 2145-2157

integration of Ty5 into regions of silent chromatin {Zou et al.), 634- 645

severe reduction of P element excision in mus309 mutants (Beall and Rio), 921-933

targeting of Ty 1 to upstream regions of RNA pol III-transcribed genes (Devine and Boeke), 620-633

Transposon tagging, use in cloning Glossyl5 in maize (Moose and Sisco), 3018-3027

Transposons conjugating plasmids as preferred tar-

gets for Tn7 (Wolkow et al.), 2145-2157

in vitro transposition of Tcl in C. elegans (Vos et al.), 755-761

integration of Ty5 into regions of silent chromatin (Zou et al.), 634- 645

masked expression of yeast copper transport gene by Ty2 (Knight et al.), 1917-1929

targeting of Tyl to upstream regions of RNA pol III-transcribed genes (Devine and Boeke), 620--633

used to study dif resolvase site insertions in E. coli (Kuempel et al.), 1162-1171; Corrigendum, 1709

Traveling waves, in chemical and biolog-

ical systems (Sager}, 2237-2250 Review

TRD. See Rapid deletion, telomeric TRF4, role in mitotic chromosome con-

densation in S. cerevisiae (Castaflo et al.), 2564-2576

Trk family, role of TrkB and TrkC in promoting neuron survival (Min- ichello and Klein), 2849-2858

tRNA. See Transfer RNA Tst-1, effects of gene deletion in mice

{Bermingham et al.), 1751-1762 Tube, functional interactions with pelle

kinase and Toll receptor (Norris and Manley), 862-872

Tubulogenesis E-cadherin in Drosophila epithelial

cell rearrangement (Uemura et al.), 659-671

role of trachealess in Drosophila (Isaac and Andrew), 103-117

Tumor cells, regulation of plasticity by TGF-~ and Ha-Ras (Oft et al.), 2462-2477

Tumor formation. See Tumorigenesis Tumor necrosis factor receptor, role of

TANK in signaling pathway {Cheng and Baltimore), 963- 973

Tumorigenesis in ATM-def ic ient mice (Xu et al.),

2411-2422 cooperativity of p53 and SCID genes

(Nacht et al.), 2055-2066 down-modulation of apoptosis leading

to tumor progression (Naik et al.), 2105-2116

in MIS receptor-deficient mice (Mish- ina et al.), 2577-2587

role of ATM (Hawley and Friend), 2383-

2388 Review p21 in ras-tumor progression (Mis-

sero et al.), 3065-3075 p53 (Ko and Prives), 1054-1072 Re-

view Src-family kinases {Lowell and Soft-

ano), 1845-1857 Review tissue-specific inactivation of p53 tu-

mor suppression in mice (Bow- man et al.), 826--835

Tupl. See also SSN6/TUP1 interaction with histones H3 and H4

(Edmondson et al.), 1247-1259 Ty 1, targeting of integration to upstream

regions of RNA pol III-transcribed genes (Devine and Boeke), 620-633

Ty2, effect on expression of yeast copper transport gene (Knight et al.), 1917-1929

TyS, preferential integration into regions of silent chromatin (Zou et al.), 634-645

Tyrosine kinase receptors. See Receptor tyrosine kinases


U1 snRNA, role in 5' splice site selection (Hwang and Cohen), 338- 35O

U I snRNP interaction with

CPSF (Lutz et al.), 325-337 Mudl3p, yeast homolog of CBP20

(Colot et al.), 1699-1708 role of CBC in association with the

cap-proximal 5' splice site {Lewis et al.), 1683-1698

U2 snRNA CUS1 as suppressor of cold-sensitive

mutations {Wells et al.), 220-232 redundancy of interactions with U6 sn-

RNA {Field and Friesen), 489- 501

U2AF, function of the 35-kD subunit (Zuo and Maniatis), 1356-1368

U6 snRNA effects of U1 snRNA on 5' splice site

selection (Hwang and Cohen), 338-350

redundancy of interactions with U2 snRNA (Field and Friesen), 489- 501

U937 cells, vitamin D 3 and induced differentiation of (Liu et al.), 142- 153

UAF. See Upstream activation factor UBF. See Upstream binding factor Ubiquitin

APC-dependent degradation of Pdslp {Cohen-Fix et al.), 3081-3093

protection of E2F-1 from proteasome degradation pathway by Rb (Hofmann et al.), 2949-2959

regulation of cyclin E turnover by cdk2 (Clurman

et al.), 1979-1990 E2F degradation by Rb family pro-

teins and adenovirus transforming proteins (Hateboer et al.), 2960-2970

Ultraviolet cross-linking, for study of U2 snRNP proteins in spliceosome assembly (Gozani et al.), 233- 243

unc-86, coupling of cell lineage asymmetry with transcription (Baumeis- ter et al.), 1395-1410

Untranslated region, 3', role in down- regulation of LIN-14 (Ha et al.), 3041-3050

UP element, role in transcription and DNA binding by e~CTD in E. coli (Gaal et al.), 16-26

Upstream activation factor requirement for TBP in recruitment of

core factor (Steffan et al.), 2551- 2563

role in RNA pol I preinitiation complex formation (Keys et al.), 887-903

Upstream binding factor, comparison with UAF (Keys et al.), 887-903

Ureteric bud, defective differentiation accompanied by wild-type p53 transgene expression (Godley et al.), 836-850

USF, role of U1 snRNA in 5' splice site selection (Hwang and Cohen), 338-,350

UTR, 3'. See Untranslated region, 3'

V

V(D)J recombination. See Recombina- tion, V(D)J

v-raf, suppression of transformation by PKC-~ (Kieser et al.), 1455-1466

vab-7, role in C. elegans posterior patterning (Ahringer), 1120-1130

Vasa, role of interaction with Oskar in Drosophila pole plasm formation (Breitwieser et al.), 2179- 2188

Vein, role in Drosophila EGF pathway (Schnepp et al.), 2302-2313

Veins, regulation of araucan and caupolican during Drosophila wing patterning (Gomez-Skarmeta and Modolell), 2935-2945

vestigial tail, as a hypomorphic allele of Wnt-3a (Greco et al.), 313-324

Virus-host interactions, POD organization and adenovirus replication (Doucas et al.), 196-207

Vitamin D3 induction of p21 (Liu et al.), 142-153 response element, in p21 promoter

(Liu et al.), 142-15,3

W

WAF-1. See p21 Whn, regulation of epithelial growth and

differentiation (Brissette et al.), 2212-2221

Wing, role of Delta in Drosophila development (Doherty et al.), 421- 434

Winged helix proteins, regulation of kidney development by BF-2 (Ha- tini et al.), 1467-1478

Wingless involvement of ~-catenin in signaling

pathway (Miller and Moon), 2527-2539 Review

role of porcupine in processing (Kad- owaki et al.), 3116-3128

wingless family role of wingless in segmentation and

specification of Drosophila mesoderm (Azpiazu et al.), 3183- 3194

vestigial tail as a hypomorphic allele of Wnt-3a (Greco et al.), 313- 324

wingless activation by Cubitus interruptus (Alexandre et al.), 2003- 2013

Wings, regulation of araucan and caupolican during development in Drosophila (G6mez- Skarmeta and Modolell), 2935- 2945

Wnt proteins

LIN-17 as receptor for LIN-44 in C. elegans (Sawa et al.), 2189-2197

MyoD induction blocked by dominant-negative Wnt in Xenopus embryos (Hoppler et al.), 2805- 2817

signaling involvement of [3-catenin {Miller

and Moon), 2527-2539 Review role of [~-catenin and Xgsk-3 in Xe-

nopus (Yost et al.), 1443-1454 Wnt-3a, regulation of mouse axial devel-

opment (Greco et al.), 313-324 Wound healing, and keratinocyte growth

factor {Guo et al.), 165-175

X chromosome, DNA hypomethylation and gene silencing (Panning and Jaenisch), 1991-2002

Xenopus APC-dependent degradation of Pdslp

(Cohen-Fix et al.), 3081-3093 effect of dominant-negative Wnt on

embryogenesis (Hoppler et al.), 2805-2817

role of [3-catenin and Xgsk-3 (Yost et al.), 1443-1454

role of Sucl homolog Xe-p9 in cell-cycle control (Patra and Dunphy), 1503-151

Xer, determinants of selectivity in site- specific recombination (Blakely and Sherratt), 762-773

XerC-D system, restriction of dif site activity in E. coil (Cornet et al.), 1152-1161

Xeroderma pigmentosa, role of XPB and XPD in p53-dependent apoptosis (Wang et al.), 1219-1232

Xgsk-3, regulation of ~-catenin {Yost et al.), 1443-1454

Xist activation of expression in response to

DNA hypomethylation (Pan- ning and Jaenisch), 1991-2002

role of DNA methylation in regulating expression of imprinted genes (Tucker et al.), 1008-1020

XPB, role in p53-dependent apoptosis {Wang et al.), 1219-1232

XPD, role in p53-dependent apoptosis (Wang et al.), 1219-1232


Yeast, budding. See also Saccharomyces cerevisiae

activation of CUP1 in strains lacking SOD1 (Liu and Thiele), 592-603

ceramide-activated protein phosphatase (Nickels and Broach), 382-394


determinants of late origin activation (Friedman et al.), 1595-1607

DIG1 and DIG2 as two novel MAP kinase targets in S. cerevisiae (Cook et al.), 2831-2848

epigenetic effects on transcription caused by mutations in a nuclear actin-related protein (Jiang and Stillman), 604-619


glucose regulation of SNF1 complex interactions (Jiang and Carlson), 3105-3115

identification of Mudl3p as homolog of CBP20 (Colot et al.), 1699- 1708

in vivo function of yTAFn90 (Apone et al.), 2368-2380

preferential integration of Ty5 into regions of silent chromatin (Zou et al.), 634-645

redundancy of MSH3 and MSH6 in mismatch repair (Marsischky et al.), 407-420

regulation and specification of replica-

tion origins (Diffley), 2819- 2830 Review

regulation of mRNA export during stress (Saavedra et al.), 1608- 1620

single-stranded telomere end-binding protein properties of Est 1 (Virta- Pearlman et al.), 3094-3104

Spkl/Rad53 regulation by Mecl-dependent protein phosphorylation (Sun et al.), 395--406

targeting of retrotransposon Tyl to upstream regions of RNA pol II- transcribed genes (Devine and Boeke), 620-633

TBP role in rDNA transcription (Stef- fan et al.), 2551-2563

3'--* 5' exonuclease role in 5.8S RNA synthesis (Mitchell et al.), 502- 513

U2 snRNP proteins role in spliceosome assembly (Gozani et al.), 233-243

Yeast, fission. See also Schizosaccharo- myces pombe

regulation of Atfl by Spcl in response to stress

{Shiozaki and Russell), 2276-- 2288

Atfl by stress-activated kinase Styl (Wilkinson et al.), 2289- 2301

S-phase onset by ORC1 homolog orpl (Grallert and Nurse), 2644- 2654

role of dmfl/rnidlin positioning of division septum (Sohrmann et al.), 2707-2719

Rum l inhibition of Cdc2 kinase and interaction with Cdc18 (Jalle- palli and Kelly), 541-552

Z

ZEBRA protein, use to study the role of TFIIA-TFIID complex formation in gene activation (Chi and Carey), 2540-2550

Zebrafish dino and swirl role in dorsoventral pat-

terning (Hammerschmidt et al.), 2452-2461

pescadillo and dead eye role in embryonic development (Allende et al.), 3141-3155

PKA regulation of Hedgehog signaling in developing embryos (Ham- merschmidt et al.), 647-658

prospects for insertional mutagenesis (Schier et al.), 3077~3080 Mini- review

Zinc-finger proteins activation of patched by Cubitus in-


identification of KAP-1 as KRAB domain corepressor (Friedman et al.), 2067-2078

as short-range transcriptional repressors in Drosophila (Gray and Levine), 700-710

specificity of LIM-based interactions (Arber and Caroni), 289-300

Zn finger proteins. See Zinc finger proteins ZO-1, identification of Drosophila homolog

(Takahisa et al.), 1783--1795


Biology ofProteolysis ] A ril 23 - 27, 1997 ~,ii!!~!~ i

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Organized by: Charles S. Craik, University o f California, San Francisco

Susan Gottesman, National Cancer Institute Mark Hochstrasser, University o f Chicago

Yuri Lazebnik, Cold Spring Harbor Laboratory

Toplcs : and Session:~ Chairs : Indude ~.:

Spatial and Temporal Controls in Development

(Kathryn Anderson) Signal Transduction (Tom Maniatis)

Protein Quality Control and Chaperones

~ i c h . H a r t l )

!!i !!i!!i!!ili!!! ! i ! ! i : : . : i ! i i ! i i ! ! i : : : ! ! ! : ! ! i ! ! i!!!i!! ! ! !! i ! ! i : ! ! i ! i ! !! i ! : : : : : i ! ! !!! i ! i ! ! : ! : ! i i ! ! i ! !!! ! : : i i ! ! i ! ! i i::!:

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CSHL particularly encourages junior scientists to present their data at the meeeting. All oral and poster

presentations will bc selected on the basis of scientific merit,

Abstract Deadl ine: January 29, 1997

Cell & Molecular Biology ofAplysia & Related Invertebrates April 16 - 20 / January 22

Regulation of Liver Gene Expression in Health and Disease April 30 - May 4 / February 5

Tyrosine Phosphorylation & Cell Signaling

May 7 - 11 / February 12 Genome M a p p i n g & Sequencing

May 14- 18 / February 19 Retroviruses

May 20 - 25 / February 26 62nd Symposium: Pattern Formation During Development

May 28 - June 2 / March 5

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1 Bungtown Rd, Cold Spring Harbor, NY 11724-2213 EmaU: [email protected]

G Fax: 516-367-8845 Phone: 516-367-8346

http://www'cshl'~ Q Reader Service No. 655

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