rome april 7-8-9 2016 viii s impar - fedra congressi · marco rossi - policlinico gemelli, rome...

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SIMPAR.EU PRESIDENTS Ma s simo All e gri University of Parma, Italy Inna Belfer McGill University Health Center, Montreal, Canada Giorgio Cruccu University La Sapienza, Rome, Italy ROME APRIL 7-8-9 2016 VIII SIMPAR VILLA PICCOLOMINI Meetings & Events Organizing Secretariat FEDRA congressi Viale dei SS. Pietro e Paolo, 21 00144 Rome, Italy Tel.+39.0652247328 Fax +39.065205625 [email protected] www.fedracongressi.com

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SIMPAR.EU

PRESIDENTS

Massimo AllegriUniversity of Parma, Italy

Inna BelferMcGill University Health Center,

Montreal, Canada

Giorgio CruccuUniversity La Sapienza, Rome, Italy

ROME APRIL 7-8-9 2016

VIII SIMPARVILLA PICCOLOMINI

Meetings & Events

Organizing SecretariatFEDRA congressi

Viale dei SS. Pietro e Paolo, 2100144 Rome, Italy

Tel.+39.0652247328Fax +39.065205625

[email protected]

SCIENTIFICCOMMITTEE

LOCAL SCIENTIFIC COMMITTEE

Marco Baciarello

Dario Bugada

Flaminia Coluzzi

Christian Compagnone

Arturo Cuomo

Andrea Fanelli

Maurizio Marchesini

Andrea Truini

University of Parma, Italy

Azienda Ospedaliero Universitaria di Parma, Italy

University La Sapienza, Rome, Italy

Azienda Ospedaliero Universitaria di Parma, Italy

Istituto Nazionale per lo Studio e la Cura dei Tumori di Napoli “Fondazione G. Pascale”, Italy

S. Orsola-Malpighi, Bologna, Italy

Azienda Ospedaliero Universitaria di Parma, Italy

University La Sapienza, Rome, Italy

Juan Francisco Asenjo

Inna Belfer

Juan Pablo Cata

Josè De Andrès

Manuela De Gregori

Luda Diatchenko

Christopher Gharibo

Vijaya Gottumukkala

Pablo M. Ingelmo

Troels Staehelin Jensen

Patricia Lavand’homme

Per-Arne Lönnqvist

Edward Mariano

Michael E. Schatman

McGill University Health Center, Montreal, Canada

McGill University Health Center, Montreal, Canada

The University of Texas-MD Anderson Cancer Center, Houston, TX, USA

Valencia School of Medicine-Valencia General UniversityHospital, Valencia, Spain

Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

McGill University Health Center, Montreal, Canada

NYU Langone Medical Center, New York

The University of Texas MD Anderson Cancer Center,Houston, USA McGill University Health Center, Montreal, Canada

Aarhus University Hospital, Denmark

St Luc Hospital UCL Medical School, Brussels, Belgium

Karolinska Institutet, Stockholm, Sweden

Stanford University School of Medicine; VA Palo Alto Health Care System, California, USA

U.S. Pain Foundation, USA

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Massimo Allegri

Francisco Asenjo

Marco Baciarello

Gabriele Baldini

Ralf Baron

Inna Belfer

Antonello Bonci

Dario Bugada

Juan Cata

Gianni Colini Baldeschi

Flaminia Coluzzi

Christian Compagnone

Giorgio Cruccu

Michele Curatolo

Alexandre F. DaSilva

José De Andrés

Manuela De Gregori

Mehul J Desai

Luda Diatchenko

James Eisenach

Andrea Fanelli

Catherine Ferland

Christopher Gharibo

Vijaya Gottomukkala

Salvatore Iannotta

Pablo M. Ingelmo

Troels S. Jensen

Leo Kapural

Henrik Kehlet

University of Parma, Italy

McGill University Health Center, Montreal, Canada

University of Parma, Italy

McGill University Health Center, Montreal, Canada

Universitaetsklinikum Schleswig-Holstein, Kiel, Germany

McGill University Health Center, Montreal, Canada

National Institute on Drug Abuse, Baltimore, USA

Azienda Ospedaliero Universitaria di Parma, Italy

The University of Texas - MD Anderson Cancer Center, Houston, TX, USA

S. Giovanni Addolorata Hospital, Rome, Italy

University La Sapienza, Rome, Italy

Azienda Ospedaliero Universitaria di Parma, Italy

University La Sapienza, Rome, Italy

University of Washington, Seattle, USA

University of Michigan Dental School, Michigan, USA

Valencia School of Medicine-Valencia General University Hospital, Valencia, Spain

Fondazione IRCCS Policlinico San Matteo, Pavia, Italy

International Spine, Pain & Performance Center Washington, DC

McGill University Health Center, Montreal, Canada

Wake Forest University, USA

S. Orsola-Malpighi, Bologna, Italy

Shriners Hospital for Children Montreal, Canada

NYU Langone Medical Center, New York, USA

The University of Texas MD Anderson Cancer Center, Houston, USA

CNR IMEM, Parma, Italy

McGill University Health Center, Montreal, Canada

Aarhus University Hospital, Denmark

Center for Clinical Research and Carolina's Pain Institute at Brookstown, Wake Forest Baptist Health,

Winston-Salem, North Carolina, USA

Copenhagen University, Denmark

Hans Kress

Patricia Lavand'homme

Bengt Linderoth

Giuseppe Lippi

Per-Arne Lönnqvist

Maurizio Marchesini

Edward Mariano

Stavros G. Memtsoudis

Bart Jan Morlion

Ferdinando Nicoletti

Stefano Palmisani

Ian Pemberton

Philip Peng

Alberto Prats

Richard Rauck

Miguel Reina

Michael E. Schatman

Mark Schumacher

Thomas R. Tölle

Andrea Truini

Jean Pierre Van Buyten

Ron Van Schaik

Jan Van Zundert

Kris Vissers

Marco Vitale

Suellen Walker

Mark Ware

Rikard Wicksell

Medical University / AKH, Vienna, Austria

St Luc Hospital UCL Medical School, Brussels, Belgium

Karolinska Institutet, Stockholm, Sweden

Azienda Ospedaliero-Universitaria di Parma, Italy

Karolinska Institutet, Stockholm, Sweden

Azienda Ospedaliero Universitaria di Parma, Italy

Stanford University School of Medicine-VA Palo Alto Health Care System, California, USA

Hospital for Special Surgery, Weill Cornell Medical College, New York, NY, USA

University Hospitals Leuven, Belgium

University La Sapienza, Rome, Italy

Guy and St. Thomas NHS Foundation Trust, London, UK

Photeomix, Ile-de-France, France

Toronto Western Hospital-University Health Network,University of Toronto, Ontario, Canada

Galino University of Barcelona, Spain

Carolinas Pain Institute, Wake Forest University, Winston-Salem, North Carolina, USA

Universidad San Pablo CEU, Madrid

U.S. Pain Foundation, USA

UCSF School of Medicine and medical Center San Francisco, USA

Technical University of Munich, Germany

University La Sapienza, Rome, Italy

AZ Nikolaas, Sint Niklaas, Belgium

Dept. Clinical Chemistry - Erasmus MC Rotterdam, Netherlands

Hospital Oost-Limburg, Genk, Belgium, Netherlands

Radboud University Nijmegen Medical Centre, Netherlands

University of Parma, Italy

GOSH/Institute of Child Health, UCL, London

McGill University Health Centre, Montreal, Canada

Karolinska University Hospital-Solna, Stockholm, Sweden

2016FACULTY

2016FACULTY

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WORKSHOP “FYD: FEED YOUR DESTINY, FIGHTING PAIN”

Presidents: MASSIMO ALLEGRI, MANUELA DE GREGORI, FABIO INTELLIGENTE, CAROLINA MUSCOLI

With the patronage

09:15 Transfer from Hotel Columbus to SIMPAR meeting

FIRST SESSION: Chairmen: MANUELA DE GREGORI, FABIO INTELLIGENTE10:00 - 10:20 Nutrition state of the art. TIZIANA STALLONE - ENPAB President10:20 - 10:40 Nutraceuticals: the state of the art VINCENZO MOLLACE University of Magna Grecia, Catanzaro10:40 - 11:00 Nutrition in patient under opioid therapy MARIANGELA RONDANELLI University of Pavia, Italy11:00 - 11:20 Microbiome and pain FRANCESCO FRANCESCHI Catholic University of Rome 11:20 - 11:40 Obesity on function and quality of life in chronic pain conditions LAURA ISABEL ARRANZ University of Barcelona, Spain11:40 - 12:00 Discussion

12:00 - 12:40 Break

SECOND SESSION: Chairmen: CAROLINA MUSCOLI, GLORIA SACCANI JOTTI12:40 - 13:00 Soy and pain INNA BELFER - McGill University, Canada13:20 - 13:40 Role of omega-3 fatty acids on inflammatory and degenerative diseases SILVIA LORENTE CEBRIAN University of Navarra - Spain13:40 - 14:00 Role of Curcumin in chronic pain MAURIZIO SALAMONE - Metagenics - Italy14:00 - 14:20 Young researcher speech. Nutritions and pain: Italian research LUIGI GIANCOTTI Hospital San Ra�aele La Pisana - Rome14:20 - 15:00 Final discussion

WORKSHOP “YOUNG AGAINST PAIN”

THANKS TO UNCONDITIONED GRANT OF GRUNENTHAL

Dedicated to young researcher who won YAP Grant

09:15 Transfer from Hotel Columbus to SIMPAR meeting

10:30 - 10:45 Authorities Welcome GUIDO FANELLI - University of Parma, Italy THILO STADLER - CEO Grunenthal Italy10:45 - 11:00 Yap: an innovative project MASSIMO ALLEGRI - University of Parma, Italy11:00 - 11:30 Research in Italy GIOVANNI LEONARDI - Italian Health Ministry11:30 - 12:30 Presentation of Yap projects

12:30 - 13:30 Break

14:00 - 15:00 Italian Scientists in the world: history of success MICHELE CURATOLO University of Washington, Seattle, USA.

THURSDAY, APRIL 07, 2016 • HALL TOFANO STUDY IN MULTIDISCIPLINARY PAIN RESEARCH

THURSDAY, APRIL 07, 2016 • HALL VALORI PANELLI STUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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WORKSHOP “OPIOIDS: HOW TO BE APPROPRIATE IN CHRONIC NON CANCER PAIN. A MASTER CLASS”

Presidents: MASSIMO ALLEGRI, THOMAS TÕLLE, ANDREA TRUINI, RENATO VELLUCCI

With the patronage

09:15 Transfer from Hotel Columbus to SIMPAR meeting

Chairmen: ANDREA TRUINI, RENATO VELLUCCI10:15 - 10:45 Opioids Pharmacology. How to choose the right drug. DIEGO FORNASARI - University of Milan - Italy10:45 - 11:15 Analgesics and bone metabolism: focus on opioids RENATO VELLUCCI - Hospital Careggi Florence, Italy11:15 - 11:45 Opioids and neuropathic pain GIORGIO CRUCCU University La Sapienza, Rome, Italy11:45 - 12:15 Addiction and opioids to take care chronic pain. When and how to predict the risk CLAUDIO LEONARDI - Hospital of Rome, Italy12:15 - 12:30 Discussion

12:30 - 13:00 Lunch

Chairmen: WILLIAM RAFFAELI, FLAMINIA COLUZZI13:00 - 13:30 Opioids and quality of life. May we really improve quality of life? BART MORLION - University Hospitals Leuven, Belgium13:30 - 14:00 Opioids and cognitive dysfunction. What do we exactly know? MASSIMO ALLEGRI - University of Parma, Italy14:00 - 14:30 Opioids in low back pain and ostheoarthritis. How to start, to continue and to prevent it becomes chronic THOMAS TÖLLE - Technical University of Munich, Germany14:30 - 15:00 Ethics and Opioids MICHAEL SCHATMAN - Research pain Foundation15:00 - 15:30 Opioids in the elderly. MICHAEL UBERALL - Institute of Neurological Sciences, Nuernberg, Germany15:30 - 15:50 Final Discussion

WORKSHOP “BILATERAL TOTAL KNEE ARTHROPLASTY: ANESTHESIOLOGISTS AND ORTHOPEDICS ALL TOGETHER TO FACE THIS NEW CHALLENGE”

Presidents: HENRIK KEHLET, PAOLO CHERUBINO, STAVROS G. MEMTSOUDIS, MASSIMO BERRUTOScientific Committee: ASTRID BEHR, F. D’ANGELO, ANDREA FANELLI, DARIO BUGADA

With the patronage

09:15 Transfer from Hotel Columbus to SIMPAR meeting

Chairmen: STAVROS MEMTSOUDIS, DARIO BUGADA10:15 - 10:40 The science behind ERAS in orthopedic surgery HENRIK KEHLET - Copenhagen University, Denmark10:40 - 11:05 The pathophysiology of BTKA and potential mechanisms of injury: Who is at risk? STAVROS MEMTSOUDIS - Hospital for Special Surgery, NY, USA 11:05 - 11:30 Anesthesia and analgesia for TKA: current evidence and new challeges for bilateral procedures ASTRID BEHR - Department of Medicine, Anesthesiology and Intensive Care, University of Padua,Padua, Italy

BTKA PRO/CONChairman: ANDREA FANELLI11:30 - 11:45 PRO - BENEFITS (USA perspective) LAZAROS POULTSIDES Hospital for Special Surgery, NY, USA 11:45 - 12:00 PRO - BENEFITS (EUROPE perspective) GIANLUCA CAPPELLERI - G Pini Hospital - Milan, Italy12:00 - 12:15 CON - RISK (USA perspective) STAVROS G. MEMTSOUDIS Hospital for Special Surgery, NY, USA12:15 - 12:30 CON - RISK (EUROPE perspective) MASSIMO BERRUTO - G Pini Hospital - Milan, Italy12:30 - 13:00 DISCUSSION

13:00 - 13:45 Lunch

14:00 - 15:30 Striking a compromise - Finding consensus in BTKA

THURSDAY, APRIL 07, 2016 • HALL BUAZZELLISTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

THURSDAY, APRIL 07, 2016 • HALL BIANCHISTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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THURSDAY, APRIL 07, 2016 • HALL RANDONESTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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WORKSHOP “PAIN IN PATIENTS WITH CANCER: EVIDENCE OF HOW DRUGS AND MINI-INTERVENTIONAL TECHNIQUES ARE USEFUL” This workshop is in Italian Language

Presidents: ARTURO CUOMO, MAURIZIO MARCHESINI

With the patronage

09:15 Transfer from Hotel Columbus to SIMPAR meeting

Chairman: ARTURO CUOMO10:15 - 10:45 NSAIDS: no devils, no angels ANDREA FANELLI Sant’Orsola Hospital, Bologna, Italy10:45 - 11:15 Opioids side e�ects in the good clinical practice: a “non problem” SILVIA NATOLI - University Tor Vergata - Rome11:15 - 11:45 Diagnosis and treatment of chemotherapy induced neuropathy FRANCO MARINANGELI - University of Aquila - Italy11:45 - 12:15 BtCP and clinical aspects: IOPS and IOPS MS studies ARTURO CUOMO - Istituto Nazionale per lo Studio e la Cura sui Tumori Hospital - Napoli, Italy12:15 - 12:30 ROOs drugs: when and which one? MASSIMO MAMMUCARI - ASL Rome, Italy12:30 - 12:45 Discussion

12:45 - 13:15 Lunch

Chairman: MAURIZIO MARCHESINI13:15 - 13:45 Evidence of mini-interventional techinques in cancer pain KRIS VISSER - Radboud University Nijmegen Medical Centre, Netherlands 13:45 - 14:15 Glia, astrocites and pain: from pathophysiology to clinical practice SABATINO MAIONE - University of Naples, Italy14:15 - 14:45 Continuous Intrathecal Therapy MARCO ROSSI - Policlinico Gemelli, Rome Italy14:45 - 15:15 Mini-interventional surgery for vertebral metastasis LUCA SERRA - Istituto Nazionale per lo Studio e la Cura sui Tumori Hospital - Napoli, Italy15:15 - 15:45 Radiofrequency and oncologic pain: new approaches? MAURIZIO MARCHESINI - Hospital of Parma15:45 – 16:00 Final discussion

THURSDAY, APRIL 07, 2016 • SERRA DE BERARDINISSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

16:00 - 18:30Chairmen: MASSIMO ALLEGRI, JAMES EISENACH PLENARY SESSION

16:00 - 16:30 Trigeminal Neuralgia GIORGIO CRUCCU

16:30 - 17:00 Telomerase activity and new biomarkers to detect pain and pain-related stress GIUSEPPE LIPPI 17:00 - 17:30 X chromosome and pain INNA BELFER 17:30 - 18:00 Opioids and chronic pain: to be or not to be? BART JAN MORLION 18:00 - 18:30 Young Agains Pain Awards

FRIDAY, APRIL 08, 2016 • HALL TOFANOSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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09:30 - 11:00Chairmen: GIORGIO CRUCCU, MANUELA DE GREGORIPAIN AND BASIC SCIENCE

09:30 - 9:50 Basic Science Translational Science Clinic - Locus coeruleus: how to see its activity and to objectivate pain JAMES EISENACH

09:50 - 10:10 Translational - QST and LEP and clinical practice GIORGIO CRUCCU

10:10 - 10:30 Clinical - Pharmacogenetics: how to determine drug response RON VAN SCHAIK

10:30 - 11:00 Discussion: how we can change our daily practice

11:30 - 13:00Chairmen: TROELS STAEHLIN JENSEN, ANDREA TRUININEUROPATHIC PAIN

11:30 - 11:50 Basic - Genetics and Neuropathic Pain LUDA DIATCHENKO

11:50 - 12:10 Translational - Diagnosis of neuropathic pain TROELS STAEHELIN JENSEN

12:10 - 12:30 Clinical - Topical treatment of neuropathic pain HANS G. KRESS

12:30 - 13:00 Discussion: how we can change our daily practice

11:00 - 11:30 Co�ee Break Session AM: Beyond the border: the basics of NSAIDs' action on pain transduction DARIO BUGADA In the Exhibition Area booth n.8

14:30 - 16:10Chairmen: MICHELE CURATOLO, MASSIMO ALLEGRI,MICHAEL E. SCHATMANA MULTIDISCIPLINARY WAY TO APPROACH CHRONIC PAIN

14:30 - 14:50 Basic - Optogenetics: a new tool to discriminate pain – focus on clinical implications ANTONELLO BONCI

14:50 - 15:10 Translational - ACT, behavioral flexibility and neuroscience: What is the role and influence of brain activity patterns, inflammatory cytokines and executive functions for behavior change in patients with chronic pain? RIKARD WICKSELL

15:10 - 15:30 From Neuroimaging to Neuromodulation: How Neurotechnologies are Providing New Insights In Vivo Into the Treatment of Migraine and other Chronic Pain Disorders. ALEXANDRE F. DASILVA

15:30 - 15:50 Discussion: how we can change our daily practice

15:50 - 16:10Co�ee break

16:10 - 18:00Chairmen: FLAMINIA COLUZZI, THOMAS TOELLEFIBROMYALGIA

16:10 - 16:30Basic Science Translational Science Clinic - Biomarkersof nociceptive processes for musculoskeletal painMICHELE CURATOLO

16:30 - 16:50Translational - Fibrodetect screening toolRALF BARON

16:50 - 17:10Clinical - Gabapentin and fibromyalgiaTHOMAS TOELLE

17:10 - 17:30Clinical - Paracetamol - still an option or a no-go?HANS G. KRESS

17:30 - 18:00Discussion: how we can change our daily practice

FRIDAY, APRIL 08, 2016 • HALL TOFANOSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

FRIDAY, APRIL 08, 2016 • HALL TOFANOSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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13:00 - 14:30 Lunch Session: Continuous wound infusion for postoperative pain - New insights and translational applicationsIn the exhibition area booth n.3

13:15 - 13:40 CWI for postoperative analgesia: evidence from the literature ANDREA FANELLI

13:40 - 14:10 Translational applications of CWI: e�ects of pain relief beyond analgesia DARIO BUGADA

09:30 - 11:00Chairmen: JOSÉ DE ANDRÉS, MARCO BACIARELLO, MARCO VITALETHE NERVE - AN HOLISTIC VIEW TO UNDERSTAND ITS FUNCTIONALITY, AND HOW TO HANDLE IT DURING TREATMENTS

09:30 - 9:50 Understanding the functionality of the nerve from a microscopic perspective. MIGUEL REINA

09:50 - 10:10 3D reconstruction of intraneural fascicular plexus ALBERTO PRATS

10:10 - 10:30 Influence of laboratory findings on clinical outcomes JOSÈ DE ANDRÈS

10:30 - 11:00 Discussion: how we can change our daily practice

FRIDAY, APRIL 08, 2016 • SERRA DE BERARDINISSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

FRIDAY APRIL 08, 2016 • SERRA DE BERARDINISSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

11:30 - 13:00Chairmen: PATRICIA LAVAND'HOMME, CHRISTIAN COMPAGNONEINFLAMMATION AND STEROIDS

11:30 - 11:50 Pain as immune suppressor VIJAYA GOTTUMUKKALA

11:50 - 12:10 Steroids: influence on hyperalgesia and neuropathic postoperative pain PATRICIA LAVAND'HOMME

12:10 - 12:30 High dose perioperative steroids: implications on rehabilitation and surgical outcome HENRIK KEHLET

12:30 - 13:00 Discussion: how we can change our daily practice

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11:00 - 11:30 Co�ee Break Session AM: Beyond the border: the basics of NSAIDs' action on pain transduction DARIO BUGADA In the Exhibition Area booth n.8

13:00 - 14:30 Lunch Session: Continuous wound infusion for postoperative pain - New insights and translational applicationsIn the exhibition area booth n.3

13:15 - 13:40 CWI for postoperative analgesia: evidence from the literature ANDREA FANELLI

13:40 - 14:10 Translational applications of CWI: e�ects of pain relief beyond analgesia DARIO BUGADA

14:30 - 16:00Chairmen: PATRICIA LAVAND'HOMME, DARIO BUGADAREGIONAL ANESTHESIA: HOW TO BLOCK THE NERVE

14:30 - 14:50 New perspective from nanotechonologies SALVATORE IANNOTTA

14:50 - 15:10 Periopertive Surgical Home and the Integral Role of Pain Medicine EDWARD MARIANO

15:10 - 15:30 Peripheral nerve blocks also in bilateral TKA STAVROS G. MEMTSOUDIS 15:30 - 16:00 Discussion: how we can change our daily practice

16:00 - 16:30Co�ee Break

16:30 - 18:00Chairmen: INNA BELFER, ANDREA FANELLICHRONIC POSTOPERATIVE PAIN

16:30 - 16:50 Genetics and chronic postoperative pain INNA BELFER

16:50 - 17:10 How to measure daily activity and chronic postoperative pain JAMES EISENACH

17:10 - 17:30 Do anticonvulsivants provide clinical benefit in acute pain and prevent chronification? CHRISTOPHER GHARIBO 17:30 - 18:00 Discussion: how we can change our daily practice

FRIDAY, APRIL 08, 2016 • SERRA DE BERARDINISSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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09:30 - 11:00Chairman: PABLO INGELMOPEDIATRICS

09:30 - 09:45 Interventional pain treatment e�cacy: what do you mean?  PABLO INGELMO 09:45 - 10:00 Using ACT to improve behavioral flexibility and functioning in children and adolescents with chronic debilitating pain. RIKARD WICKSELL

10:00 - 10:15 E�ects of pain exposure in early life: laboratory evaluation of mechanisms SUELLEN WALKER

10:15 - 10:30 New transdermal platform for analgesics and other drugs. PER-ARNE LÖNNQVIST

10:30 - 11:00 Discussion: How we can change our practice.

11:30 - 13:00Chairman: PER-ARNE LONNQVISTPEDIATRICS

11:30 - 11:45 Systemic and central regulation of catecholamines in the peri-operative period. CATHERINE FERLAND 11:45 - 12:00 E�ects of pain exposure in early life: clinical data from the EPICure preterm cohort. SUELLEN WALKER 12:00 - 12:15 Semi-objective measures in clinical pain assessment CATHERINE FERLAND 12:15 - 12:30 Should we use cannabinoids in children and adolescents? PABLO INGELMO 12:30 - 13:00 Discussion: How we can change our practice. PER-ARNE LÖNNQVIST

FRIDAY, APRIL 08, 2016 • HALL VALORI PANELLISTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

FRIDAY APRIL 08, 2016 • HALL VALORI PANELLISTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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11:00 - 11:30 Co�ee Break Session AM: Beyond the border: the basics of NSAIDs' action on pain transduction DARIO BUGADA In the Exhibition Area booth n.8

13:00 - 14:30 Lunch Session: Continuous wound infusion for postoperative pain - New insights and translational applicationsIn the exhibition area booth n.3

13:15 - 13:40 CWI for postoperative analgesia: evidence from the literature ANDREA FANELLI

13:40 - 14:10 Translational applications of CWI: e�ects of pain relief beyond analgesia DARIO BUGADA

14:30 - 16:10PRO-CON EPIDURAL STEROIDS - SORTING THROUGH THE STEROID CONTROVERSYResponsible of PRO-CON: MAURIZIO MARCHESINIRegistrations for the PRO-CON sessions are free and only open to the first 50 members

14:30 - 14:50 What is the best steroid to inject epidurally? Particulate steroid CHRISTOPHER GHARIBO

14:50 - 15:10 What is the best steroid to inject epidurally? Dexamethasone LEO KAPURAL 15:10 - 15:30 Transforaminal MAURIZIO MARCHESINI

15:30 - 15:50 Interlaminar JOSÈ DE ANDRÈS

15:50 - 16:10 Discussion: how we can change our daily practice

16:10 - 16:30Co�ee Break

16:30 - 18:00PRO-CON SESSION: RADIOFREQUENCY COOLED VS THERMALResponsible of PRO-CON: MARCO BACIARELLORegistrations for the PRO-CON sessions are free and only open to the first 50 members

16:30 - 16:50 Cooled LEO KAPURAL

16:50 - 17:10 Continuous STEFANO PALMISANI

17:10 - 17:30 Pulsed JAN VAN ZUNDERT

17:30 - 18:00 Discussion: how we can change our daily practice

FRIDAY, APRIL 08, 2016 • HALL VALORI PANELLISTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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14:30 - 16:30Nanotechnology and pain: new perspectives in chronic pain therapy

Round table: MASSIMO ALLEGRI, CHRISTIAN COMPAGNONEMANUELA DE GREGORI, CAROLINA MUSCOLI, DARIO BUGADA

14:30 - 16:30WIP and FIPP: Italian round table about opportunities of FIPP certification KRIS VISSER, PIERLUIGI MANCHIARO, MASSIMO BARBIERI, RICHARD RAUCK, JAN VAN ZUNDERT

FRIDAY APRIL 08, 2016 • HALL BIANCHISTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

09:30 - 11:00Chairmen: BENGT LINDEROTH, MARCO BACIARELLOINTERVENTIONAL PAIN MANAGEMENT

09:30 - 9:50 Basic - Refractory Chronic Pain Screening Tool (RCPST): a feasibility study to assess practicality and validity of identifying potential neurostimulation candidates. GIORGIO CRUCCU

09:50 - 10:10 Translational: physiological mechanisms of Novel Neuromodulation Techniques: How does new knowledge fit the Gate Control Concept? BENGT LINDEROTH

10:10 - 10:30 Translational: Stimulation of the dorsal root ganglion an evidence based alternative to spinal cord stimulation in the treatment of neuropathic conditions JEAN-PIERRE VAN BUYTEN

10:30 - 10:50 Clinical - High frequency LEO KAPURAL

10:50 - 11:00 Discussion: how we can change our daily practice

11:00 - 11:30Co�ee Break

11:30 - 12:50Chairmen: LUDA DIATCHENKO, MAURIZIO MARCHESINI, GIANNI COLINI BALDESCHIDISCOGENIC PAIN

11:30 - 11:50 Activomics as new biomarker for discogenic pain IAIN PEMBERTON

11:50 - 12:10 Clinical - Discogenic pain: which evidence based treatment RICHARD RAUCK

12:10 - 12:25 Clinical - Epiduroscopy: a diagnostic or operative procedure? STEFANO PALMISANI

12:25 - 12:40 Clinical - Evidence based approach in diagnosing and treating low back pain JAN VAN ZUNDERT

12:40 - 12:55 12-Month Outcomes of Trandiscal Biacuplasty Compared to Conventional Medical Management for the Treatment of Discogenic Low Back Pain DESAI MEHUL

12:55 - 14:30Lunch

SATURDAY, APRIL 09, 2016 • SERRA DE BERARDINISSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

SATURDAY, APRIL 09, 2016 • SERRA DE BERARDINISSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

24 25

14:30 - 16:00Chairmen: MASSIMO ALLEGRI, KRIS VISSERSLOW BACK PAIN

14:30 - 14:50 Basic - E�ect of minocycline on lumbar radicular neuropathic pain KRISS VISSERS

14:50 - 15:10 Clinical - Ultrasound in the diagnosis and treatment of chronic pain PHILIP PENG

15:10 - 15:30 Translational - Cannabinoids and low back pain MARK WARE

15:30 - 16:00 Discussion: how we can change our daily practice

SATURDAY, APRIL 09, 2016 • SERRA DE BERARDINISSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

26

09:30 - 11:00Chairmen: MANUELA DE GREGORI, ARTURO CUOMOONCOLOGICAL NEUROPATHIC PAIN

09:30 - 9:50 The anticancer antibiotic mithramycin-A inhibits TRPV1 expression in dorsal root ganglion neurons. MARK SCHUMACHER

09:50 - 10:10 OPRM1 and other "pain genes" as new biomarker to detect cancer recurrence MANUELA DE GREGORI

10:10 - 10:30 Mini-invasive treatment in cancer pain KRISS VISSERS 10:30 - 11:00 Discussion: how we can change our daily practice

11:00 - 11:30Co�ee Break

11:30 - 13:00Chairmen: VIJAYA GOTTUMUKKALA, DARIO BUGADACANCER ANESTHESIA - CURRENT STATUS AND FUTURE PHILOSOPHY

11:30 - 11:50 Inflammation-based scores: a new method for patient-targeted strategies and improved perioperative outcome in cancer patients. PATRICIA LAVAND'HOMME 11:50 - 12:10 Immunonutrition JUAN PABLO CATA 12:10 - 12:30 Fast Track Surgery in cancer Surgery GABRIELE BALDINI

12:30 - 13:00 Discussion: how we can change our daily practice

13:00 - 14:30 Lunch

14:30 - 16:00Chairman: TROELS STAEHELIN JENSENNEUROLOGY

14:30 - 14:50 New drugs for treating neuropathic pain. Evidence from animal studies FERDINANDO NICOLETTI

14:50 - 15:10 How diagnostic tests disclose a mechanism based approach to neuropathic pain ANDREA TRUINI

15:10 - 15:30 Evidence of central origin TROELS STAEHLIN JENSEN 15:30 - 16:00 Discussion: how we can change our daily practice

SATURDAY, APRIL 09, 2016 • HALL TOFANOSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

SATURDAY, APRIL 09, 2016 • HALL TOFANOSTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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09:30 - 11:00Chairmen: VIJAYA GOTTOMUKKALA, CHRISTIAN COMPAGNONEPRO-CON REGIONAL ANESTHESIA IN ABDOMINAL SURGERY WHICH BLOCK?Registrations for the PRO-CON sessions are free and only open to the first 50 members

09:30 - 9:50 TAP BLOCK GABRIELE BALDINI

09:50 - 10:10 General Anesthesia PATRICIA LAVAND'HOMME

10:10 - 10:30 Paravertebral block EDWARD MARIANO

10:30 - 11:00 Discussion: how we can change our daily practice

11:00 - 11:30 Co�ee Break

11:30 - 13:00PRO-CON: NEUROPATHIC PAIN: CENTRAL OR PERIPHERALRESPONSIBLE ANDREA TRUINIRegistrations for the PRO-CON sessions are free and only open to the first 50 members

11:30 - 11:50 Evidence for a peripheral origin ANDREA TRUINI

11:50 - 12:10 Evidence for a central origin TROELS STAEHELIN JENSEN

12:10 - 12:40 Discussion: how we can change our daily practice

13:00 - 14:30Lunch

14:30 - 15:30PRO-CON: OPIOIDS IN ACUTE PAINRegistrations for the PRO-CON sessions are free and only open to the first 50 members

14:30 - 14:50 PRO ANDREA FANELLI

14:50 - 15:10 CON JUAN PABLO CATA

15:10 - 15:30 Discussion: how we can change our daily practice

SATURDAY, APRIL 09, 2016 • HALL VALORI PANELLISTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

SATURDAY, APRIL 09, 2016 • HALL VALORI PANELLISTUDY IN MULTIDISCIPLINARY PAIN RESEARCH

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1 Perioperative Care/Acute Pain GORAVANCHI FARZIN USAUT MD Anderson Cancer Center, UT MD Anderson Cancer Center, Houston, United States E�ect of caudal nerve block on pain management of penile prosthesis surgery

2 Chronic Pain GHARAEI HELEN GHARAEI IRAN Milad hospital, Tehran, Iran Sphenopalatine Ganglion Block a Jack of all Trades Block

3 Chronic Pain GHARAEI HELEN GHARAEI IRAN Milad hospital, Tehran, Iran Radiofrequency Thermal Ablation in Painful Myeloma of the Clavicle

4 Chronic Pain GHARAEI HELEN GHARAEI IRAN Milad hospital, Tehran, Iran Transforaminal Epidural Block or Selective Nerve Root Block?

5 Chronic Pain ALLAM HEMAT EGYPT National Research Centre, Medical Research Centre of Excellence, Cairo, Egypt Evaluation of Serum beta-endorphin and Substance P variations in knee osteoarthritis patients exposed to LASER acupuncture

6 Chronic Pain ALLARD RENÉ GERMANY Grünenthal GmbH, Not applicable, Aachen, Germany An exploratory clinicaltrials.gov review for patient reported outcomes (PROs) in cancer pain

7 Chronic Pain TINNIRELLO ANDREA ITALY Azienda Ospedaliera, “M.Mellini”, Chiari, Italy Genicular nerves ablation in severe knee pain management: a comparison between pulsed and continuos radiofrequency, preliminary results.

8 Chronic Pain PIRACCINI EMANUELE ITALY Anesthesia and intensive care unit, Young against pain italian group (YAP), Morgagni Pierantoni hospital, Forli, ItalyThe use of lidocaine 5% patch and Palmitoilethanolamide for male pelvic pain : a case Report

9 Perioperative Care/Acute Pain KONKAYEV AIDOS KAZAKHSTAN Astana Medical University, Institution of Traumatology and Orthopedia, Astana, KazakhstanImprovement of postoperative analgesia in patients after knee surgery

10 Chronic Pain BAZZICHI LAURA ITALY Division of Rheumatology, Azienda Ospedaliero-Universitaria Pisana, Pisa, ItalyFibromyalgia and therapeutic use of decoction of Cannabis Flos

11 Pain and Basic Science SCOTTI VALERIA ITALY Fondazione IRCCS Policlinico San Matteo, Pavia, ItalyDoes research group enhance impact on scientific community or general public discussion: an alternative metric based evaluation?

12 Pain and Basic Science POVOROZNYUK VLADYSLAV UKRAINE D.F. Chebotarev Institute of gerontology NAMS Ukraine, Ukrainian scientific-medical centre for the problems of osteoporosis, Kyiv, UkraineNeuropathic pain component in patients with osteoporosis

13 Chronic Pain VALENTE ADRIANA ITALY Department of Anesthesiology, Critical Care and Pain Therapy, Parma, ItalyThe Multidisciplinary Approach in Chronic Pelvic Pain: a Case Report

14 Chronic Pain CARLOMAGNO MARIELLA ITALY Department of Neuroscience, Anesthesiology and Drug Administration Unit of Anesthesiology, Intensive Care and Antalgic Therapy. YAP-Young Against Pain, University of Naples Federico II, Napoli, ItalyScrambler therapy in the management of coccydynia: a case report

15 Perioperative Care/Acute Pain OPPERER MATHIAS AUSTRIA Department of Anesthesiology, Paracelsus Medical University, Salzburg, AustriaComparison of Ropivacaine 0.375% vs. 0.75% for cervical plexus block for carotid endarterectomy shows no di�erence in postoperative diaphragmatic function

16 Chronic Pain RICCIOTTI MARIA ADELAIDE ITALY Hospice Villa Speranza Gemelli Medical Center, YAP (Young Against Pain) Italian Group, Università Cattolica del Sacro Cuore, Rome, ItalyPrevalence and charateristic of pain in non-oncological patients in palliative care:preliminar data of a perspective observation study

17 Chronic Pain DESAI MEHUL USAInternational Spine, Pain & Performance Center, George Washington University Medical Center, Washington, United StatesA Prospective, Randomized, Multi-Center, Open-Label Clinical Trial Comparing Intradiscal Biacuplasty to Conventional Medical Management for Discogenic Lumbar Back Pain

18 Perioperative Care/Acute Pain LEE JUSTIN USA Mayo Clinic, Jacksonville, USAParavertebral Blocks and General Anesthetic: Comparison of the Incidence of Urinary Retention after Inguinal Hernia Repair

19 Perioperative Care/Acute Pain TORRANO VITO ITALY Azienda ospedaliera della Provincia di Lodi, LODI, “Serratus plane” continuous block for breast surgery: a case report with a novel technique

20 Chronic Pain DI PASQUALE RAFFAELLA ITALY Anesthesiology and Intensive Care Unit, Azienda Ospedaliera Bolognini, Seriate, Italy Mixed technique for pudendal verve block in vuvlvodynic patients

21 Pain and Basic Science FAKHRY MICHAEL USAVariations of technique in lumbar transforaminal epidural steroid injections by interventional pain medicine practices

22 Chronic Pain C. LEONE ITALYDepartment of Neurology and Psychiatry, University Sapienza, RomeWhich is the best evoked potential technique for assessing the nociceptive system?Preliminary results of a neurophysiological study in healthy humans

23 Chronic Pain A. PEPE ITALYDepartment of Neurology and Psychiatry, Sapienza University, RomeCentral sensitization as the mechanism underlying pain in jointhypermobility syndrome/Ehlers-Danlos syndrome, hypermobility type

FRIDAY, APRIL 8TH 2016 - 13:00 - 14:30POSTER SESSION

FRIDAY, APRIL 8TH 2016 - 13:00 - 14:30POSTER SESSION

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GENERAL INFORMATIONREGISTRATION

VILLA PICCOLOMINIVia Aurelia Antica 164 · 00165 Rome · Italy

Registration fee Medical Doctors € 600,00

Registration fee Nurse/Administrative Sta� € 300,00

Residents fee € 150,00

One Day Only - April 7th € 100,00

Rates are VAT included.Registration fee includes Scientific program, Proceedings, Welcome cocktail,

Congress Bags, Co�ee Breaks and Lunches.

Registration online: www.simpar.euCancellation Policy Fees for registration will be refunded in full if written noticecancellation is received by february 1st 2016

No refund will be given for cancellation received after february 1st 2016 or if you register but fail to attend.

Please send your written cancellation request to:[email protected]

CME AccreditationSIMPAR 2016 was accredited by EACCME and assigned 14 European CME Credits (ECMEC).

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