rosai's collection of surgical pathology seminarsumbilicus .. . jhe mass was nillitender and...

* * * * * * * * * * * * * * * * * ·* * * * * * * * * * * * * * * * * * * CALIFORNIA TUMOR TISSUE REGISTRY

LOS ANGELES COUNTY - UNIVERSITY OF SOUTHERN CALIFORNIA

PROTOCOL

FOR

MONTHLY STUOY SLIDES

MARCH 1987

GENERAL PATHOLOGY

CASES SUBMITTED BY

VALLEY PRESBYTERIAN HOSPITAL , VAN NUYS, CALIFORNIA

* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *

CONTRIBUTOR: Dennis Kasimian, M. D. MARCH 1987 - CASE NO. 1 Van Nuys, California

TISSUE FROM: Hip ACCESSION NO. 25121

CLINICAL ABSTRACT:

History: A 28-year-old woman first noted a subcutaneous tumor on the left hip when she was two months pregnant. The twmor grew slowly over the ensuing months prior to her delivery, and. was removed shortly after.

Phystcal examination: A· mass -was present on the left buttock which was fluctuant, soft, and ·apparently well-defined.

SURGERY : (October 11 ., 1983)

The mass, which involved the gluteal ·muscles, was widel~ excised.

GROSS PATHOLOGY: ·

Submitted was a 14 x 12 x 8 em. · Multilobulated tumor weighing 925 grams. It was co~posed of soft, tan-white to yellow-tan nodules, separated by fine connective .t .issue septae. There were multiple foci of hemorrhage and cysts measuring 0.3 to 1.0 em. in diameter.


TISSUE FROM: Parotid gland ACCESSION NO. 25051

CLINICAL ABSTRACT:

History: A 77-year-old woman was admitted for a mass· of the left parotid area and neck. The mass had reportedly been present for more than 50 years, over which time it had very slowly enlarged.

Physical examination: A 15 x 10 em. non tender mass was pre'sent over the left anterior neck. Neurol-ogic examination of the face was normal

SURGERY: (August 15, 1983)

Superficial parotidectomy and modified neck dissection were performed.

GROSS PATHOLOGY:

The mass measured 14 x 9 x 6 em. The surface was purple-tan to yellow, with a well-formed capsule. The cut surface Wi!S. tan, rubbery, ·and showed cystic spaces up to 0.8 em. in diameter. Calcification was present in some areas.


TISSUE FROM: Superior mediastinum ACCESSION NO. 25057

CLINICAL ABSTRACT:

Histor~: A 69-year-old man was . evaluated for chest discomfort and shortness o breath of 4 weeks' duration. He had a 50 pack-year smoking history, and had lost 5. lb. ·over the ·past month. There was no history of pulmonary disease.

Physical examination: Non-contributory

Radiographs: Chest x-ray showed a mass in the anterior-superior mediastinum.

SURGERY: (August I, 1983)

The tumor was immediately substernal, and projected into the left pleural space. It was easily removed by sharp dissection.

GROSS PATHOLOGY:

The specimen was a 9 x 6.5 x 6 em. mass with a red-tan to gray-tan bosselated external surface. The cut surface had cysts up to 2.5 em. in diameter, and was predominantly soft and tan to white. The tumor was invested by a thin fibrous capsule.

CONTRIBUTOR: Dennis Kasimian, M. D. ~lARCH 1987 - CASE NO. 4 Van Nuys, California

TISSUE FROM: Breast ACCESSION NO. 24952

CLINICAL ABSTRACT:

History: An 82-year-old woman presented with a left· breast mass. Four years previously, she had. an intraductal papilloma removed from the same breast. Over a 6 month period she -developed a. firm, non-tender breast mass. There was no family history of breast cancer. . .

Physical examination: The left breast showed heated scar, beneath which was a mobile 6 x 8 ,em .. mass. The left axilla contained on_e pal pable lymph node. There· was no nipple discharge or mass in the opposite breast.

SURGERY: (May 9, 1983)

Simple mastectomy was performed ..

GROSS PATHOLOGY :

The tumor measured 8.5 x 7.5 x 6 em. and had a. bosselated .surface. The cut surface was firm, faintly .nodular; and pink-tan to yellow. Some areas appeared consistent with cartila9e or bone.

CONTRIBUTOR : Dennis Kasimian, M. D. MARCH 1987 - CASE NO . 5 Van Nuys, ·California

TISSUE FROM: Forearm ACCESSSION NO. 24088

CLINICAL ABSTRACT:

History: · A 17-Year-old man was admitted for a tumor of the left forearm which had be~o present for 2\ years. For the past· 18 months, the tumor had been stable in size.

SURGERY: (December, 1980)

The tumor, which was attached to the periosteum by a small pedicle, was removed.

GROSS PATHOLOGY:

Submitted was a 4.5 x 3.0 x 3.0 em. mass with a bosselated external surface and a homogeneous tan-white to yel low-white ~oft . cut surface.


TISSUE FROM: Retroperitoneum ACCESSION NO. 25487

CLINICAL ABSTRACT:

History: A 46-year-old man presented with subumbilical burning pain and fatigue of sereval months' 'duration. He had not l.ost weight, and was unaware of any masses.

Physical examination: An 11 x 13 em. solid nontender mass was present in the right abdomen. It clinically appeared to be attached to the iliac bone.

Radiographs: Abdominal CT scan showed a large right retroperitoneal mass involving the iliopsoas muscle. An intravenous pyelogram showed medial deviation of the right ureter.

SURGERY: (March 15; 1985)

The mass was excised. It appeared to be attached to a large retroperitoneal nerve.

GROSS PATHOLOGY:

Submitted was a rubbery, dark red to tan mass measuring 12 x 9.5 x ~.5 em. A 2.5 em. length of nerve was attached to the outside of the mass. ,The cut surface showed multiple cysts filled with tan mucoid material or blood.

CONTRIBUTOR: Dennis Kasimian, M. 0. MARCH 19~7 -.CASE NO. 7 Van Nuys, Cal ifor:nia

TISSUE FROM: Omentum ACCESSION NO. 25B5B

CLINICAL ABSTRACT: . ' History: ·'A 63-year-old man was_ admitted to- the hospital for abdominal

pain. Eighteen years before, he had a "grape-fruit-sized" mass removed· from the pelvis. He was well until several months.before admission, w~en he developed progressively mQre. severe abdominal .Pain. He had no nausea, vomiting, change in bowel habits , or blood in the stool. · ··

Ph sical examination: The abdomen 1~as slightly proniineht· witli fullness in the left _upper qua rant. The rectal- examination was .normal.

Radiographs: Ultrasound .and C'J' scan showed a 15 em. ·mass· in the left abdomen extending from ~ear the kidney to the pelvic brim.

. . SURGERY: (October 24, 1984)

A large mass was resected from the omentum, and several . implants were removed from the small boweJ.

GROSS PATHOLOGY: .. The omentum contained a pink-tan mass measuring 17 x 13 x 9 em .. Th!'!

cut surface wa~ · tan- brown wi.th light ye 11 ow matt l ing .. · Near . the. outer surface were cystic structures containing stra~1 colored fluid .and measuring up to 3 em. in diameter.

CONTRIBUTOR: Dennis Kasimian, M. D. ~~RCH 19B7 - CASE NO. 8 Van Nuys , .California

TISSUE FORM: Lower neck ACCESSION NO. 25390

CLINICAL ABSTRACT:

History: A 54-year-old woman presented with an enlarging mass in the left lower neck of several months' duration. Thyroid scan showed a nonfunctioning mass which .displaced the le~t . lobe · Of the thyroid superiorly and posteriorly.

Physical examination: Blood pressure 132/90, pulse 76. A 4.6 em. mass was associated with the l¢ft lobe of the thyroid gland. There was no hyperreflexia.

SURGERY : (September 16 , '1983) .

A cystic mass extended form the superior. mediastinum to the larynx. The mass was removed, with a portion of the l eft lobe of the thyroid gland.

GROSS PATHOLOGY :

Submitted was a cystic lesion measuring 7. 5 x 7 x 3 em. It was filled with 100 ml. of straw-colored fluid, and had a thin, pink-tan wall with a unifo~ily smooth internal surface.

CONTRIBUTOR: Rae Josels.on, M. 0. MARCH 1987 - CASE NO. 9 & 10 Van Nuys, California

TISSUE FROM:· Retroperitoneum ACCESSION NO. 25848

CLINICAL ABSTRACT: ..

History: A 68-year-old woman compla.ined of abdominal · swelling; fati'gue, and urinary frequency for 3-4 months. There was no' history of .weight loss. She had a hysterectomy 'and tii 1 atera 1 sa 1 pi n!}9.-oophorectomy many ye_ar previously.

Physical examination: · A large pelv.ic mass was. present, extending to the umbilicus .. . Jhe mass was nillitender and smooth to palpation. The .remainder of the -physical' exam was unremarkable.

SURGERY: {November 6, 1986)

At surgery two separate masses were .di scover\!d. A mass was present i-n the right retroperitoneum, extending from the renal vein to the internal inguinal ring {case 9). A second mass extended from the right retroperitoneum to the lateral chest and abdominal 1vall . (case 10).

GROSS PATHOLOGY: .. :'

Submitted was a 16 x lJ. X 9 em. mass weighing 1 ,020, grams. The surfa'i:e was smooth, glistening, and pink-tan .. Sectioning showed a homogeneous, bulging, gelatinous tan.,yellow cut surface wit.h faint trabec\llations (case 9) .• Accompanying this was a 250 grams mass' measqri~g 14 x 10.5 x 4.5 em. This mass was glistl!ning, yellow-tan, and faintly lobulated {case J.O) • .

CONTRIBUTOR: John Glassco, M. 0. MARCH 1987 -CASE NO. 11 Van Nuys, California

TISSUE FROM: Ileum ACCESSION NO. 25898

CLINICAL ABSTRACT:.

History: A 34-year-old woman presented with se~ere intermittent right upper quadrant pain. This was accompanied by belching, constipation, and vomiting. The.re w.as no improvement with cimetidine, azulfidine, or antispasmodics. The patient had ~reviously had a hysterectomy and appendectomy.

Physical examination: Non-contributory

Radiographs: A small bowel series showed marked stenosis of the mid-ileum.

SURGERY: (January 19, 1987)

A fungatin9 tumor extended through the full thickness of the- ileal wall. Palpable mesenteric lymph nodes were present. 'The mass was resected.

GROSS PATHOLOGY:

Submitted was a portion of ileum 11.5 em. long and 7 em. in circumference . A 5.5 em. hard, mul tinodular white mass extended through the wall. The mucosa overlying the mass was pushed up, but showed no lesi.ons. The cut surface of the mass was glistening, white,_ and homogeneous.

CONTRIBUTOR: Dennis Kasimian, M. D • . ~~RCH 1987 - CASE NO. 12 Van Nuys, California

TISSUE FROM: · Pancreas ACCESSION NO. 25919

CLINICAL ABSTRACT:

History: A 75-year-old woman was admitted for .vaginal bleeding of 2 week's duration. The patient was diabetic and' ~~d hypertension. In the eight months before admission she had lost 80 pounds.

Physical examination: A hard, hard umbilical mass measuring 3.5 em. in diameter was present.

SURGERY: (June 7, 1986)

At laparotomy, the uterus was markedly enlarged and there were masses in the umbiljcus and posterior gastric wall. A separate mas.s, from which this case is taken, was present in the tail of the ,pancreas.

GROSS PATHOLOGY:

Sections of uterus, stomach, and abdominal wall showed a malignant mixed mullerian tumor, with metastasis .of the epithelial component. The separate specimen from the pancreas meas11red 6.5 x 5.3 x s·.o em. and weighed 188 grams·. This tumor had a lobulated surface with a thin fibrous capsule. The cut surface was pink-tan to yellow and showed multiple cysts measuring up to 0.4 em. in diameter. ·

STUDY GROUP CASES FOR

MARCH 1987

CASE NO. 1 - ACCESSION NO. 25121

LOS ANGELES: Myxoid liposarcoma - 8

OAKLAND: Round cell liposarcoma - 5; myxoid liposarcoma - 5

MARTINEZ: liposarcoma with rou~d cell and myxoid components - 11

FRESNO: Liposarcoma , mixed type (small cell and myxoliposarcoma) - 12; embryonal rhabdosarcoma - 1

SEATTLE: liposarcoma, myxoid and round cell - 6

INDIANA: Myxoid liposa~coma - 4

LONG BEACH: Myxoid liposarcoma with round cell component- 9

BAKERSFIELD: Liposarcoma - 8; mesenchymoma - 1

SAN FRANCISCO: Liposarcoma, myxoid - 4; liposarcoma, round cell - 4

SAN BERNARDINO (INLAND): Liposarcoma {NOS) - 7; myxoid liposarcoma- 2

FOLLOW-UP:

The tumor bed was re-excised in a second operation. The patient developed widespread metastasis, however, and died 18 months after her first surgery.

FILE DIAGNOSIS:

Myxoid liposarcoma, hip

REFERENCES:

Reszel, P. A., Soule, E. H., Coventry, M. 8.: Liposarcoma of Extremities and Limb Girdles: Study of 222 Cases. J. Bone Joint Surg. (Am.) 48:229-244, · 1966.

Kindblom, L., Angervall, L., Svendsen, P.: Liposarcoma- A Clinicopathologic, Radiographic and Prognostic Study. Acta. Pathol. Microbio1. Scand. (Suppl.) 253:1-71, 1975.

Evans, H. L.: Liposarcoma. A Study of 55 Cases with a Reassessment of It's Classification. Am. J. Surg. Pathol. 3:507-523 , 1979.

CASE NO. 2 - ACCESSION NO. 25051 MARCH 1987

LOS ANGELES: Pleomorphic adenoma (mixed tumor) - 12

OAKLAND: Pleomorphic adenoma - 9; carcinoma 1n pleomorphic adenoma - 1

MARTINEZ: Pleomorphic adenoma - 12

FRESNO: Pleomorphic adenoma - 12; pleomorphic with squamous cell carcinoma - 1

SEATTLE: Pleomorphic adenoma- 6.

INDIANA: Pleomorphic adenoma - 4

LONG BEACH: Mixed tumor, myoepithelial variant- 9

BAKERSFIELD: Mucoepidermoid carcinoma- 1; pleomorphic adenoma- 8

SAN FRANCISCO: Mixed tumor (pleomorphic adenoma) - 7; dermal analog tumor of salivary gland - 1

SAN BERNARDINO (INLAND): .Pleomorphic adenoma - 9

FOLLOW-UP:

The patient was discharged four days after surgery, and subsequently lost to follow-up.

FILE DIAGNOSIS:

Pleomorphic adenoma, parotid

REFERENCES:

Ryan, R. E. , DeSanto, L. W., Weiland, L. H., Devine, K . . D., Beahrs, 0. H.: Cellular Mixed Tumors of the Salivary Glands. Arch. Otolaryngal. 104:451-453, 1978.

Welsh, R. A., Meyer, A. T.: Mixed Tumors of Salivary Gland, Histogenesis. Arch. Pathol. 85:433-447, 1968.

Malett, K. J., Harrison, M. S.: The Recurrence of Salivary Gland Tumors. J. Laryngol. Otol. 85:43g-448, 1971 .


LOS ANGELES: Benign thymoma- 11; lymphangioendothelioma - 1

OAKLAND: Thymoma - 10

MARTINEZ: Thymoma - 12

FRESNO: Thymoma - 12; lymphangioma - 1

SEATTLE: Thymoma - 6

INDIANA: Thymoma - 4

LONG BEACH: Thymoma (cystic) - 9

BAKERSFIELD·: Thymoma - 8; follicular carcinoma , thyroid - 1

SAN FRANCISCO: Thymoma, spindle cell type - 8

SAN BERNARDINO (INLAND): Thymoma- 9

FOLLOW-UP:

There was no evidence of recurrence as of July 1984.

SPECICAL STAINS:

Immunoperoxidase stains for keratin were positive.

FILE DIAGNOSIS:

Benign thymoma, mediastinum

REFERENCES:

Gray, G. F., Gutowski, .W. T.: Thymoma. Am. J. Surg . Patho1. 3:235-249, 1979.

LeGo1ovan, D. P., Abell, M. R.: Thymomas. Cancer 39:2142-2157, 1977.

Levine, G. D., Rosai, J.: Thymic Hyperplasi!l and Neoplasia: A Review of Current Concepts. lium. Pathol. 9:495-515, 1978.

Levine, G. D., Rosai, J., Bearman, R. M., Poll iack, A.: The Fine Structure of Thymoma with Emphasis on It's Differential Diagnosis. A Study of Ten Cases. Am. J. Pathol. 81:49-66, 1975.


LOS ANGELES: Os teo sarcoma - 12 .

OAKLAND: Metaplastic carcinoma - 10

MARTINEZ: Metaplastic carcinoma - 12

MARCH 1987

FRESNO: Myositis ossificans - 9; osteogenic sarcoma - 4

SEATTLE: Osteogenic sarcoma - metaplastic breast carcinoma vs. primary sarcoma of breast - 6

INIDANA: Osteosarcoma of soft tissue - 4

LONG BEACH: Osteogenic sarcoma - 9

BAKERSFIELD: Extraskeletal osteogenic sarcoma - 9

SAN FRANCISCO: Extra osseous osteosarcoma - 3; reactive metaplastic bone - 5

SAN BERNARDINO (INLAND): Extraosseoijs osteosarcoma - 9

FOLLOW-UP:

In February 1984, the patient presented with lung and bone metastases. Lung biopsy showed metastatic sarcoma, and she received chemotherapy and radiotherapy.

SPECIAL STAINS:

Immunohistochemical stains showed strong positive reaction with vimentin but no staining with keratin.

FILE DIAGNOSIS:

Osteosarcoma, breast

REFERENCES:

Smith, B. H., Taylor, H. B.: Occurrence of ·Bone and Cartilage im Mammary Tumors. Am. J. Clin. Pathol. 51:610-618, 1969.

l.lombart-Bosh, A., Peydro, A.: Malignant Mixed Osteogenic· Tumors of . the Breast: An Ultrastructural Study of Two Cases. Virchows Arch. (Pathbl . Anat.) 366:1-14, 1975.

Kaufman MW, et al: Carcinoma of the Breast with Pseudosarcomatous Metaplasia. Cancer 53:1908-1917, 1984.

Mufarrij AA, Feiner HD: Breast Sarcoma with Giant cells and Osteoid. Am. J. Surg. Pathol. 11:225-230, 1987.

Going JJ, Lumsden AS, AndersoA- TJ: A classical Osteogenic Sarcoma of The Breast: Histology, Immunohistochemistry and Ultrastructure. Histopathol 10: 631-641, 1986.

,


LOS ANGELES: Periosteal fibroma - 12

OAKLAND: Fibromatosis - 9; paraosteal fibroma - 1

MARTINEZ: Nodular fasciitis - 12

MARCH 1987

FRESNO: Fibroma of tendon sheath origin - 12; myxoid tumor of nerve sheath - 1

SEATTLE: Benign nerve sheath tumor - 4; fibromatosis - 2

INDIANA: Periosteal desmoid - 3; periosteal fibroma - 1

LONG BEACH: Fibroma - 9

BAKERSFIELD: Periosteal desmoid - 8; non-ossi fying fibroma - 1

SAN FRANCISCO: Periosteal fibroma - 8

SAN BERNARDINO (INLAND}: Neurofibroma- 4; neurilemoma - 4; periosteal desmoid - 1

FOLLOW-UP:

No follow-up is available.

SPECIAL STAINS:

Tumor cell stained positively foRvimentin, but negatively for S-100 protein.

FILE DIAGNOSIS:

Periosteal fibroma, forearm

REFERENCES:

Spjut HJ, Dorfman HD, Fechner RE. Tumors of Bone and Cartilage. Armed Forced Institute of Pathology. Washington D. C. (1971), pp. 267-269.


LOS ANGELES: Schwannoma - 12

OAKLAND: Schwannoma - 8; malignant schwannoma - 2

MARTINEZ: Neurilemmoma - 12

FRESNO: Schwannoma - 13

SEATTLE: Schwannoma - 6'

INDIANA: Schwannoma - 2; neurofibroma - 2

LONG BEACH: Schwannoma - 9

BAKERSFIELD: Benign schwannoma - 9

SAN FRANCISCO: Schwannoma {neurolemmoma) - 8

SAN BERNARDINO {INLAND): Neurilemmoma- 9

FOLLOW-UP:

MARCH 1987

Following surgery, the patient had numbness of the anterior thigh. There was no evidence of recurrent tumor in August 1986.

SPECIAL STAINS:

Tumor cells were strongly positive for S-100 protein.

FILE. DIAGNOSIS:

Schwannoma, retroperitoneum

REFERENCES:

. Fisher, E. R., Vuzevski, V. 0.: Cytogenesis of Schwannoma (Neurilenmoma). Neurofibroma, Dermatofibroma, and Dermatofibrosarcoma as Revealed by Electron Microscopy. Am. J. Clin. Pathol. 49:141-154, 1968.

Harkin, J. C., Reed, R. J.: Tumors of the Peripheral Nervous System. Armed Forces Institute of Pathology: Washington D. C. , {1969), pp. 29-59.

CASE NO. 7 - ACCESSION ~0. 25858 MARCH 1987

LOS ANGELES: Hemangiopericytoma, potentially malignant - 12

OAKLAND: Hemangiopericytoma - 10

MARTINEZ: Hema.ngiopericytoma , malignant - 12

FRESNO: Malignant hemangioperi cytoma - 5; hemangiopericytoma • 8

. SEATTLE: Pericytoma, low-grade· malignant- 6

INDIANA: Hemangiopericytoma - 4

LONG BEACH: Hemangiopericytoma - 9

BAKERSFIELD: Hemangiopericytoma - 9

SAN FRANCISCO; Hemangiopericytoma, low grade malignancy- 8

SAN BERNARDINO (INLAND): Hemangiopericytoma · 9

FOLLOW-UP:

The patient did well until two years later, when a pelvic mass was found on routine rectal examination. A 10 em. tumor was removed , with multiple tumor implants, and a diagnosis of malignant hemangiopericytoma rendered.

FILE DIAGNOSIS:

Hemangiopericytoma, retroperitoneum

REFERENCES:

Angervall, L., Kindblom, L. G., Nielsen, J. M., Stener, B., Svendsen, P.: Hemangiopericytoma: A Cl in.icopathologic. Angiographic and Micrographic Study. Cancer 42:2412~2.427, 1978.

Enzinger, F. M. , Smith, B. H.: Hemangiopericytoma. An Analysis of 106 Cases. Hum. Pathol. 7:61-82, 1976.

Me Master, M. J., Soule, E. H., Ivins, J. C.: Hemangiopericytoma A Clinicopathologic Study and long-term Follow-up of 60 patients . Cancer 36: 2232-2244, 1975.


LOS ANGELES: Parathyroid cyst - 12

OAKLAND: Parathyroid cyst - 10

MARTINEZ: Parathyroid cyst - 12

FRESNO: Parathyroid cyst - 13

SEATTLE: Cystic parathyroid adenoma. - 6

INDIANA: Parathyroid cyst - 4

LONG BEACH: Parathyroid cyst - 9

BAKERSFIELD : Parathyroid cyst - 8; thyroid cyst - 1

SAN FRANCISCO: Benign parathyroid cyst - 8

SAN BERNARDINO (INLAND): Parathyroid cyst- 9

FOLLOW-UP :

As of October 1985 the patient was well .

FILE DIAGNOSIS:

Parathyroi d cyst, thyroid

REFERENCES:

MARCH 1987

Rogers, L. A., Fetter, B. F., Peete, W. P. J.: Parathyroid Cyst and Cystic Degeneration of Parathyroid Adenoma . Arch. Pathol. 88:476-479, 1969.

Wang, C-A, Vickery, A. L;, Maloof, F. : Large Parathyroid Cysts Mimicking Thyroid Nodules. Ann. Surg. 175:448-453, 1972.


LOS ANGELES: Well differentiated liposarcoma- 12

OAKLAND: Myxoid liposarcoma- 10

MARTINEZ: Liposarcoma, well differentiated - 12

MARCH 1987

FRESNO: Myxosarcoma - 3; well differentiated liposarcoma with focus of dedifferentiation - 1; lllYXOid liposarcoma - 9· ·

SEATTLE: liposarcoma, well differentiated - 6

INDIANA: Liposarcoma, sclerosing type - 2; liposarcoma, lllYXOid type - 2

LONG BEACH: Well differentiated liposarcoma - 8; myxoid liposarcoma - 1

BAKERSFIELD: Liposarcoma, low grade - 9

SAN FRANCISCO: Myxoid liposarcoma - 8

SAN BERNARDINO ~INLAND): Myxoid liposarcoma- 9

FOLLOW-UP:

Not available

FILE DIAGNOSIS:

Well differentiated liposarcoma, retroperitoneum

REFERENCES:

Lagace, R. , Jacob, s., Seemayer, T. A.: Myxoid Liposarcoma: An Electron microscopic Study: Biological and Histogenetic Considerations. Virchows. Arch. (Pathol. Anat.) 384:159-172, 1979.

Azumi N, Curtis J, Kempson Rl, Hendrickson MR: Atypical and Malignant Neoplasms showing 1 ipomatous differentiation. A StuCiy of 111 Cases. ·Am. J. Surg. Pathol ·11:161-183, 1987.

Wetzel, W., Alexander, R.: Myxoid Liposarcoma, Am. J. C1in. Pathol. 72: 521-528' 1978.


LOS ANGELES: Well differentiated liposarcoma - 12

OAKLAND: Well differentiated liposarcoma - 10

MARTINEZ: Liposarcoma, well differentiated - 12

MARCH 1987

FRESNO: Well differentiated liposarcoma - 4; myxoid liposarcoma - 9

SEATTLE: liposarcoma, well differentiated - 6

INDIANA: Liposarcoma, lipoma-like - 4

LONG BEACH: Well differentiated li.posarcoma - 8; lipomatous liposarcoma - 1

BAKERSFIELD: Liposarcoma, low grade - 9 ·

SAN FRANCISCO: Myxoid liposarcoma, differentiated - 8

SAN BERNARDINO (INLAND): Well differentiated liposarcoma - 9

FOLLOW-UP:

Not available

FILE DIAGNOSIS:

Well differentiated liposarcoma, retroperitoneum

REFERENCES:

Bolen, J. W., Thorning, D.: Benign Lipoblastoma and Myxoid Liposarcoma: A Comparative Light and Electron Microscopic Study. Am. J. Surg . Pathol. 4: 163-174, 1980.

' .

Evan.s, H. L., Soule, E .. H., Winkelmann, R. K.: Atypical Lipoma, Atypica Int'ramuscular Lipoma and Well Differentiated Retroperitoneal Liposarcoma: A Reappraisal of 30 Cases Formerly Classified as Well Differentiated liposarcoma. Cancer 43:574-584, 1979.

Shmookler, B. ~1., Enzinger, F. M.: Pleomorphic Lipoma: A Benign Tumor Simulating Liposarcoma. A Clinicopathologic Analysis of 48 Cases . Cancer 47: 126-133' 1981.


LOS ANGELES: Leiomyosarcoma - 12

OAKLAND: Smooth muscle tumor of uncertain malignant potential - 10

MARTINEZ: Leiomyosarcoma - 12

FRESNO: Leiomyosarcoma - 13

SEATTLE: Gut stromal tumor, malignant (leiomyosarcoma) - 6

INDIANA: Leiomyosarcoma - 4

LONG BEACH: Leiomyosarcoma - 9

BAKERSFIELD: Leiomyosarcoma, il eum - 9

SAN FRANCISCO: Leiomyosarcoma - 8

SAN BERNARDINO (INLAND): Leiomyosarocma - 9

FOLLOW-UP:

Not available

FILE OIGANOSIS:

Leiomyosarcoma, ileum

REFERENCES:

Ranchod, M., Kempson, R. L.: Smooth, Muscle Tumors of the Gastrointestinal Tract and Retroperltoneum. Cancer 39:255-262, 1977.

Kay, S., Still, W. J. S.: A Comparative Electron Microscopic Study of a Leiomyosarcoma and Bizarre Leiomyoma (Leiomyobl astoma) of the Stomach. Am. J. Clin. Pathol. 52:403-413, 1969.


LOS ANGELES:· Serous cystadenoma (microcystic adenoma) - 12

OAKLAND: Microcystic adenoma - 10

MARTINEZ: Microcystic adenoma (serous cystadenoma) - 12

FRESNO: Serous cystadenoma - 13

SEATTLE: Microcystic aaenoma - 6

INDIANA: Microcystic aqenoma - 4

LONG BEACH: Serous cystadenoma (microcystic adenoma) - 9

BAKERSFIELD: Pancreati c serous cystadenoma - .9

SAN FRANCISCO: Hicrocystic adenoma - 8

SAN BERNARDINO (INLAND): l~icrocystic cystadenoma - 9

FOLLOW-UP:

Not available

FILE DIAGNOSIS:

Serous cystadenoma (microcystic adenoma), pancreas

REFERENCES:

Campagne, J., Oertel, J. E.: Microscystic Adenomas of the Pancreas (Glycogen Rich Cystadenomas) : A Clinicopathologic Study of 34 Cases. Am •. J. Cl in. Pathol. 69:289-298, 1978.

Bogomletz, W. V., Adnet, J. J . , Wi dgren, S., Stavrou, M., Mclaughlin, J. E.~ Cystadenoma of the Pancreas: A Histological Histochemical and Ultrastructural Study of Seven ~ases. Histopathology 4:309-320, 1980.

Hodgkinson, D. J., Remine, W. H. , Weiland, L. H. :. Pancreatic Cystadenoma: A Clinicopathologic Study of 45 Cases. Arch. Surg. 113-:512-519, 1978.

Shorten SD, et al: Microcystic adenomas (Serous Cystadenomas) of The Pancre·as: Clinicopathologic, Immunohistochemical and electron Microscopic Study of 8 Cases. Am J. Surg. Pathol . 10:365-372, 1986.

rosai's collection of surgical pathology seminarsumbilicus .. . jhe mass was nillitender and...

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