salt reduction and pe classes for youth have long-term benefits

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PharmacoEconomics & Outcomes News 616 - 13 Nov 2010 Salt reduction and PE classes for youth have long-term benefits A simulation model investigating the lifetime costs and cardiovascular outcomes for a cohort of 15-year-old US adolescents shows that while screen-and-treat strategies for managing elevated BP among adolescents appear to be cost effective; broad-reaching, policy- based interventions, such as salt reduction or increasing physical education (PE) classes potentially deliver better "bang for the buck". Screen-and-treat strategies involved finding and treating adolescents considered to be at the highest risk. The most cost effective of these strategies involved pharmacologic or surgical treatment of adolescents with secondary hypertension or left ventricular hypertrophy, which cost approximately $18 000/QALY for boys and $47 000/QALY for girls. However, incremental cost- effectiveness analyses showed that strategies such as a population-wide salt reduction campaign, increased PE classes, and a structured exercise programme all dominated the screen-and-treat strategies. A salt reduction campaign was considered to be cost saving for boys and would cost $647/QALY for girls, while increasing physical activity among adolescents by increasing PE classes would cost approximately $11 000/QALY for boys and $35 000/QALY for girls. The researchers conclude that "Policy and environmental interventions that broadly affect BP level of all youths may be more effective and more cost- effective; it is thus of high priority to ensure the implementation of these strategies in parallel to any expansion of clinical services to screen and treat children and adolescents with elevated BP." Wang YC, et al. Effectiveness and Cost-Effectiveness of Blood Pressure Screening in Adolescentsin the United States. Journal of Pediatrics : 16 Sep 2010. Available from: URL: http://dx.doi.org/10.1016/j.jpeds.2010.07.058 803042903 1 PharmacoEconomics & Outcomes News 13 Nov 2010 No. 616 1173-5503/10/0616-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved

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Page 1: Salt reduction and PE classes for youth have long-term benefits

PharmacoEconomics & Outcomes News 616 - 13 Nov 2010

Salt reduction and PE classes foryouth have long-term benefits

A simulation model investigating the lifetime costsand cardiovascular outcomes for a cohort of 15-year-oldUS adolescents shows that while screen-and-treatstrategies for managing elevated BP among adolescentsappear to be cost effective; broad-reaching, policy-based interventions, such as salt reduction or increasingphysical education (PE) classes potentially deliver better"bang for the buck".

Screen-and-treat strategies involved finding andtreating adolescents considered to be at the highest risk.The most cost effective of these strategies involvedpharmacologic or surgical treatment of adolescents withsecondary hypertension or left ventricular hypertrophy,which cost approximately $18 000/QALY for boys and$47 000/QALY for girls. However, incremental cost-effectiveness analyses showed that strategies such as apopulation-wide salt reduction campaign, increased PEclasses, and a structured exercise programme alldominated the screen-and-treat strategies. A saltreduction campaign was considered to be cost savingfor boys and would cost $647/QALY for girls, whileincreasing physical activity among adolescents byincreasing PE classes would cost approximately$11 000/QALY for boys and $35 000/QALY for girls.

The researchers conclude that "Policy andenvironmental interventions that broadly affect BP levelof all youths may be more effective and more cost-effective; it is thus of high priority to ensure theimplementation of these strategies in parallel to anyexpansion of clinical services to screen and treatchildren and adolescents with elevated BP."Wang YC, et al. Effectiveness and Cost-Effectiveness of Blood Pressure Screeningin Adolescentsin the United States. Journal of Pediatrics : 16 Sep 2010. Availablefrom: URL: http://dx.doi.org/10.1016/j.jpeds.2010.07.058 803042903

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PharmacoEconomics & Outcomes News 13 Nov 2010 No. 6161173-5503/10/0616-0001/$14.95 © 2010 Adis Data Information BV. All rights reserved