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SCIENCE NEW SERIES SUBSCRIPTION, $6.00 VOL. 100, No. 2600 FRIDAY, OCTOBER 27, 1944 SINGLE COPIES, .15 Serving America's Laboratories 3 CONVENIENTLY- LOCATED . . DISTRIBUTION STOCKS 2NEW YORK, No Y. a ~ ~~ . PITTSBURGH, PA. Consult Catalog 90 "Modern Laboratory Appliances" for your requirements Manufactured and Distributed by FISHER SCIENTIFIC CO. ElMER AND AMEND Pittsburgh, Pa. - St. Louis, Mo. New York, N. Y. Headquarters for Laboratory Supplies Science: published weekly by The Science Press, Lancaster, Pa. Entered as second-class matter July 18, 1923, at the Post Office at Lancaster, Pa., under the Act of March 3, 1879. ST. LOUIS, MOO

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Page 1: SCIENCE · 2005. 7. 19. · SCIENCE-ADVERTISEMENTS Determination ofcomparative melting points in the Merck Research Laboratories. MERCKhas THE--RIGHT COMBINATION for Laboratory Chemicals

SCIENCENEW SERIES SUBSCRIPTION, $6.00VOL. 100, No. 2600 FRIDAY, OCTOBER 27, 1944 SINGLE COPIES, .15

Serving America's Laboratories

3 CONVENIENTLY-LOCATED . .DISTRIBUTIONSTOCKS

2NEWYORK, No Y.a ~ ~ ~ .

PITTSBURGH, PA.

Consult Catalog 90"Modern Laboratory Appliances"

for your requirements

Manufactured and Distributed by

FISHER SCIENTIFIC CO. ElMER AND AMENDPittsburgh, Pa. - St. Louis, Mo. New York, N. Y.

Headquarters for Laboratory SuppliesScience: published weekly by The Science Press, Lancaster, Pa.

Entered as second-class matter July 18, 1923, at the Post Office at Lancaster, Pa., under the Act of March 3, 1879.

ST. LOUIS, MOO

Page 2: SCIENCE · 2005. 7. 19. · SCIENCE-ADVERTISEMENTS Determination ofcomparative melting points in the Merck Research Laboratories. MERCKhas THE--RIGHT COMBINATION for Laboratory Chemicals

2 SCIENCE-ADVERTISEMENTS

GEOLOGYVolcanoes of

The Three Sisters Region,Oregon Cascades

By HOWEL WILLIAMSUniversity of' California Publications

Bulletin of the Department ofGeological Sciences

Volume 27, No. 3, pp. 37-84,plates 4-12, 4 figures in text, 1 map

Price, 75 cents

UNIVERSITY OF CALIFORNIAPRESS

Berkeley 4 Los Angeles 24

Please address all communications to the Universityof California Press, Berkeley 4, California.

New (3d) Edition Just Ready

A TEXTBOOK OF HISTOLOGYTHE FUNCTIONAL SIGNIFICANCE

OF CELLS ANDINTERCELLULAR SUBSTANCES

By E. V. COWDRYProfessor of Anatomy, The School of Medicine;

Washington University, St. Louis, Mo.

Thoroughly revised. Large octavo, 426 pages,illustrated with 317 engravings, 13 in colors.

Cloth, $7.00.

In the preparation of the third edition of thiswork, the author has simplified his text by theomission of certain details so as to give increased

emphasis to what he believes to be the fundamen-

tals. The object has not been simply to expeditethe teaching of histology, but rather to permit a

closer focussing of attention on the correlation ofform and function by stressing the dynamics of thebody in action.

LEA & FEBIGERWASHINGTON SQUARE, PHILADE HA 6, PA.

Hold the temperature of thatWATER BATH or JACKET

with a

MILLER THERMOSTATIC ATTACHMENTCarl D. Miller, 827 Salem St., North Andover, Mass.

OPPORTUNITIES AVAILABLE

(a) Two assistant professors of gross anatomy, oneof whom should have special training in neuro-anat-omy; also an assistant professor of microscopic anat-omy; university medical school. (b) Associate pro-fessor and, also, assistant professor in bacteriologyand parasitology; teaching and research experiencerequired; East. (c) Instructor in bacteriology; manor woman with Ph.D. degree with good fundamentaltraining in bacteriology, chemistry required; South.(d) Instructor In biology; freshman course; stateuniversity. (e) Medical writer; man or woman withscientific background; if not trained must be capableof being trained; large pharmaceutical company;East. S10-1, Medical Bureau (Burneice Larson,Director) Palmolive Building, Chicago, Illinois.

Assistant Librarian, B.S. in library science or in-dustrial research library experience. Chemicaltraining desirable. Reference Librarian with ad-vanced degree in chemistry, literature and abstract-ing experience. Postwar opportunities excellent.Applicants must meet regulations of W.M.C. BoxMCG, C/o SCIENCE, Lancaster, Penna.

CHEMIST, Ph.D. 1933, desires academic or indus-trial position. Extensive experience in biochemicalresearch; hormones, viruses, snake venom; proteins,steroids. Solid background in organic and physicalchemistry. Some teaching experience. 32 publi-cations. Age 37, draft II-A. Address inquiriesto: Box "MW," c/o SCIENCE, Lancaster, Pa.

OPPORTUNITYTo develop your Microscope by adding additional Objectiveswhich I offer for Sale as follows:NEW VOIGTLANDER Objectives: 1/12 Homog. Imm.

No. 3AJ, No. 1 and EuryskopObjective 60 mm

OCULARS 2 and 3 alsoNEW ZEISS Objectives AB, 5, 7 and 1.8 mmZEISS OCULARS 2, 3 and 5

Make offer by writing Box 500, c/o SCIENCE. Lancaster, Pa.

Special Mats No. 740-Kfor the Assay of Pemidllla

Write for Literature eteo ,

Samples and Que stlen

Schleicher & Sekwell Co.Plant and Lab: South Lee. Mass.Head Office: 116-118 West 1h St.

New York 11. N. Y.

WANTED at once 45 holders single filmto fit plate back for Zeiss contax camera.Write: M R 3400, University of California,P. 0: Box 5190, Metropolitan Station, LosAngeles 55, California.

IA

l

I

VOL. 100, No. 2600

Page 3: SCIENCE · 2005. 7. 19. · SCIENCE-ADVERTISEMENTS Determination ofcomparative melting points in the Merck Research Laboratories. MERCKhas THE--RIGHT COMBINATION for Laboratory Chemicals

SCIENCE-ADVERTISEMENTS

Determination of comparative melting points inthe Merck Research Laboratories.

MERCK has

THE --RIGHT

COMBINATION

for Laboratory Chemicals

Fine chemicals for the professions and industrysince 1818.

One of the unique "Merck Cross Tables" in theMerck Analytical Laboratories.

A corner of the Merck Packaging Laboratory. Stock points strategically located from coast tocoast.

n-MERCK & CO., Inc. Am4nu/a in6kma- RAHiWAY. N. J.Science, 10-27-44

i Please send me the following charts: Name ..........................................................

i Q Sensitivity of Qualitative Reactions Company.Position .j Periodic Chart of the Elements Str..t.I.

dSensitivity Chart City ................... State .

Lmuu Ad-----uu....--.w----~n.a~r~~mniw---A_ __*-----Ad_uumuinui,ruiu , - .** I

3OcToBim 27, 1944

Page 4: SCIENCE · 2005. 7. 19. · SCIENCE-ADVERTISEMENTS Determination ofcomparative melting points in the Merck Research Laboratories. MERCKhas THE--RIGHT COMBINATION for Laboratory Chemicals

4 SCIENCE-ADVERTISEMENTS VOL. 100, No. 2600

ADAMS SAFETY-HEAD CENTRIFUGEImproved Model As Supplied to U. S. Army and Navy

5000* R.P.M. on D.C.This centrifuge offers important advantages over the conventional units. The tubes aresuspended at a fixed 520 angle-thus faster sedimentation is achieved by the shorter dis-tance particles are required to travel . . . creating mass, and reaching the bottom morequickly. The tubes remain in the angular position and no stirring up of sediment results.

CT-1001 ADAMS SENIOR SAFETY-HEAD CENTRIFUGE for SIX 15ml. TUBES.Exclusive of tubes or shields Each $49.50CT-1000 Same as above, but complete with six round bottom brass shields withrubber cushions and three each graduated and ungraduated taper bottom 15 ml.glass tubes.Without protective cap or underguard ................................Each $52.50CT-1055 UNDERGUARD......................... Each $ 3.50CT-1050 PROTECTIVE CAP ..Each $ 2.50Above centrifuges have universal motors for 110-volt A.C. or D.C. current. Ad-ditional charge of $2.00 is made for 220 volt universal motors.

* With underguard No. CT-1055 with six 15 ml. tubesloaded. 4200 R.P.M. on A.C. with same load.

MICRO and SEMI-MICRO tubes (5 ml. to 0.5ml.) can be accommodated by purchasing extrashields. No adapters are required.

CLAY-ADAMS CON!fmeRe m~~~~~~IC

JUST OUT-Write f or our newcatalog on your letter-head, please, giving usyour institutional affil-iation and department.

.........................................................................................

SCIENCE-ADVERTISEMENTS VOL. 100, No. 26004

Page 5: SCIENCE · 2005. 7. 19. · SCIENCE-ADVERTISEMENTS Determination ofcomparative melting points in the Merck Research Laboratories. MERCKhas THE--RIGHT COMBINATION for Laboratory Chemicals

OCOBI 27 194 SCE C-A V TIE NT 5

EASIER VITAMIN ORDERING__

_.E

____Has___

i_____

AN IMPROVED SUPPLY PICTURE prevails on most of thevitamins of our manufacture.

FOR INSTANCE, RIBOFLAVIN is off allocation entirely.

ASCORBIC ACID-Vitamin C-Users of 30 kilos or less per monthcan now get immediate delivery at any time without allocation.

FOR LATEST COMPLETE INFORMATION and prices, keepin touch with our Vitamin Division. And whenever you order vita-mins-B1, B2, B6, C or E-specify 'Roche' and rest assured ofgetting the finest science can produce, in the most desirable forms,at the lowest prices consistent with uncompromising quality.

HOFFMANN-LA ROCHE, INC. * VITAMIN DIVISION * NUTLEY 10, NEW JERSEY

OcToBzR 27, 1944 SQENCE-ADVERTISEXENTS 5

Page 6: SCIENCE · 2005. 7. 19. · SCIENCE-ADVERTISEMENTS Determination ofcomparative melting points in the Merck Research Laboratories. MERCKhas THE--RIGHT COMBINATION for Laboratory Chemicals

From wintudr

Lethal exsanguination of two condemned criminals was the method employed by vonHaller to determine human blood volume in the 18th century. Interest in the diagnosisand treatment of shock since then has led to a relatively simple technique, involvingintravenous injection of a measured amount of blue dye, following which a small speci-men of the blood plasma is compared spectroscopically with a standard to determinethe dilution of the dye. However, application of this method proved hazardous becausethe dye frequently caused serious reactions when injected. War required speedy solutionofthis problem, and the task was given to the Warner Institute for Therapeutic Research.

Warner scientists developed and carried out a new synthesis which yielded thedye in a state of exceptional purity. Methods of standardization, ampuling and steriliz-ation were developed to make it safe for injection. A compact kit was also devised fordetermination of plasma volume (or degree of shock) under field conditions.

The Warner Institute for Therapeutic Research makes available to investigatorsthroughout the country the facilities of a large research organization with departmentsspecializing in all of the basic branches of the medical sciences.

Inquiries should be addressed to:

lWilliam R. Warner & Co., Inc.113 West 18th Street, New York 11, N. Y.

Makers of Pharmaceuticals, Ampuls, Sulfonamides and Special Therapeutic Agents.

Page 7: SCIENCE · 2005. 7. 19. · SCIENCE-ADVERTISEMENTS Determination ofcomparative melting points in the Merck Research Laboratories. MERCKhas THE--RIGHT COMBINATION for Laboratory Chemicals

CRYSTALLINE BIOTIN

oa /te$4wl , al eea(* Standardized solutions of crystalline biotin for microbiological assay

procedures are available in following quantities:1 ml. ampuls-25 micrograms 1.00 each . . . . 7.50 dozen

Since crystalline biotin is now more readily available, the special SMACObiotin concentrates will be discontinued when present supplies are exhausted.

For further information, write

GENERAL BIOCHEMICALS, INC. * CHAGRIN FALLS, OHIODIVISION WYETH INCORPORATED

__~~~~~~~~~~~

'fr

Page 8: SCIENCE · 2005. 7. 19. · SCIENCE-ADVERTISEMENTS Determination ofcomparative melting points in the Merck Research Laboratories. MERCKhas THE--RIGHT COMBINATION for Laboratory Chemicals

8 SCIENCE-ADVERTISEMENTS VOL. 100, No. 2600~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~

ENLIST YOUR

War Sonds' The Qualities That Make a Better MicroscopeMM- -l--- T~n Yi l o-ft DfU- - 1 or rA)iLiUt mi UrrUcLrnU PCToday B&L Microscopes ... in

American laboratories and in battle areas throughout theworld . . . are being subjected to the most rigorous tests

microscopes have ever undergone. Out of this experience,

combined with this company's war production experience

... against a background of nearly a century of optical de-velopment work . . . will come the finer microscopes you

will someday buy.A microscope, that will do the work you want it to

under any conditions, is more than an assembly of lensesand mechanical parts. It's a product of many things . . .

from the manufacture of the optical glass to the grindingof the lenses and the final precision assembly . . . but most

of all it's a product of experience.

in 18/4 iiauscn a LomD proiuuceu its urst iiiii-rubtupcb. . .followed in 1878 by the first mass produced precisionmicroscopes, two outstanding developments which were

to make more and better microscopes available to all.From that day to this Bausch & Lomb Microscopes have al-ways represented . . . and will continue to represent . . . thelatest and the best in microscope design and performance.

BAUSCH LO*MB

OPTICAL CO., ROCHESTER, N.Y.

EST. 1853

MAKERS OF OPTICAL GLASS AND A COMPLETE LINE OF OPTICAL INSTRUMENTS FOR MILITARY

USE, EDUCATION, RESEARCH, INDUSTRY AND EYESIGHT CORRECTION AND CONSERVATION

SCIENCE-ADVERTISEMENTS VOL. 100, No. 26008

Page 9: SCIENCE · 2005. 7. 19. · SCIENCE-ADVERTISEMENTS Determination ofcomparative melting points in the Merck Research Laboratories. MERCKhas THE--RIGHT COMBINATION for Laboratory Chemicals

SCIENCE

VOL. 100 FRIDAY, OCTOBER 27, 1944 No. 2600

The Fifth Cleveland Meeting of the American Asso-ciation for the Advancement of Science and Asso-ciated Societies: Edited by DL F. R. MOULTON ...... 365

SomeGeneralImpressions...............................

Registration............................................................................................................General Sessions ............................... 366The Presidential Address ........ ....................... 366Annual Association-Sigma Xi Address ............................... 367Annual Association-Phi Beta Kappa Address .................. 367National Geographic Society-Smithsonian Institution

Lecture..................................................................................................................

Symposia.............................................................................................SectionandSociety Programs ........................... ................ 369

Expenses of the Meeting ..............................x

Minutesof the Council Meeting .................. ................ 377TheAcademy Conference ......... ......................... 378

Obituary:Recent Deaths .................................. 379

Scientific Events:The United Nations Standards Coordinating Com-mittee; The National Industrial Chemical Confer-ence and the Chemical Exposition; Memnorial Meet-ing in Honor of Marie Sklodowska Curie ........................ 379

Scientific Notes and News .......... ......................... 380Discussion:Fundamental Biological Research in Wartime:LIEUTENANT WILLIAM TRAGER. Comments on Com-paratwve Studies in Human Biology: PROFESSORM. F. ASHLEY MONTAGU. The Correct Names ofParasites in Human Malaria: DR. ENRIQUE BEL-

T-iN. The Generic Name of the Sand Fly: FRAN-CISHEMMING ........................................... 383

Scientific Books:Spectroscopy: DR. WILLIAM F. MEGGERS ........... ............ 385

Special Articles:Experimental and Clinical Observations on In-creased Mechanical Fragility of Erythrocytes: DR.SHU CHU SHEN, DR. W. B. CASTLE and ELEANORM. FLEMING. Progressive Ascending Paralysis inDogs Due to Deficiency of a Vitamnin B ComplexFactor Found in Yeast: SUSAN GowER SMITH.The Inactivation of Antibiotics: DR. C. J. CAVAL-

LITO and DR.JOHNHAYSBAILEY .......................................... 387Scientific Apparatus and Laboratory Methods:Enhanced Production of Penicillin in Fluid MediumContaining Cellophane: DR. GREGORY SHWARTZ-

MAN ........................................... 390Science News ........................................... 10

SCIENCE: A Weekly Journal devoted to the Advance-ment of Science. Editorial communications should be sentto the editors of SCIENCE, Lancaster, Pa. Published everyFriday by

THE SCIENCE PRESSLancaster, Pennsylvania

Annual Subscription, $6.00 Single Copies, 15 Cts.SCIENCE is the official organ of the American Associa-

tion for the Advancement of Science. Information regard-ing membership In the Association may be secured fromthe office of the permanent secretary in the SmithsonianInstitution Building, Washington 25, D. C.

THE FIFTH CLEVELAND MEETING OF THE AMERICANASSOCIATION FOR THE ADVANCEMENT OF SCIENCE

AND ASSOCIATED SOCIETIESEdited by Dr. F. R. MOULTON

PERMANENT SECRETARY

FROM September 11 to 16, 1944, the one hundredand eleventh meeting of the American Associationfor the Advancement of Science was held in Cleve-land, Ohio. Four meetings of the association hadpreviously been held in Cleveland, the first in 1853and later ones in 1888, 1913 and 1931. A meetingscheduled for Cleveland in 1852 was canceled becauseof an epidemic of yellow fever that prevailed fromthe Ohio River southward. This was the only timein 96 years that a meeting of the association was

interfered with by disease, but during that intervalthere were seven years in which the association heldno meetings because of war. Five of those yearswere 1861 to 1865, inclusive, when those who tt-gether had won their political freedom became fora time bitter enemies; and the remaining two were the

years 1942 and 1943, when nearly all the world wasat war.Only 43 papers were presented at the Cleveland

meeting in 1853, and 215 in 1888. In 1913 the num-ber had increased to 813, and in 1931 to 1,830. Atthe recent meeting the number of addresses andpapers had declined to fewer than 1,000 because ofthe many distractions due to the war. The member-ship of the association in 1853, 1888, 1913 and 1931was 940, 1,764, 8,333 and 19,059, respectively. Thisyear at a corresponding date was 25,000, in roundnumbers.

SOME GENERAL IMPRESSIONSFirst on the list of general impressions of the Cleve-

land meeting is that it was much better than any one