siva arunasalam , m.d. high desert heart institute
DESCRIPTION
Siva Arunasalam , M.D. High Desert Heart Institute. ProArgi-9+ Active HDHI Study. 9 Healthy Subjects + Dan Austin Ages: 22-54 + d60an. ProArgi-9+ Active HDHI Study. Measure lactic acid levels during vigorous exercise Lactic acid accumulates when body goes into oxygen debt - PowerPoint PPT PresentationTRANSCRIPT
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Siva Arunasalam, M.D.High Desert Heart Institute
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ProArgi-9+ Active HDHI Study• 9 Healthy Subjects + Dan Austin• Ages: 22-54 + d60an
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ProArgi-9+ Active HDHI Study• Measure lactic acid levels during vigorous exercise• Lactic acid accumulates when body goes into oxygen
debt• More vigorous the exercise the longer the duration of
exercise, higher the lactic acid accumulation• Lactic Acid causes muscle fatigue• Lactic acid accumulation decreases muscle
performance
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ProArgi-9+ Active HDHI Study
Hypothesis:
If L-Arginine increases muscle blood flow, then there will be less lactic acid accumulation.
Thus increasing endurance & muscle recovery.
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ProArgi-9+ Active Formulation
• Blocks oxidation of LDL cholesterol• Multiple studies performed with 100-200mg. with benefits
including helping maintain BP already in normal range• Ingredients of PA9Active have more than 200mg. per
serving of Quercetin• Protection: Antioxidant against factors such as
oxidative stress, radiation, cell damage
Quercetin: Broad Spectrum Protection
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QuercetinMechanism of Action
• Free Radical scavenger (Antioxidant)• Promotes a healthy inflammation response,
especially in fat tissue• Regulates gene expression• Supports natural stress responses• Boosts immunity• Source of Quercetin: Grape skins, Red Onions,
Green Tea to Tomatoes --> Flavonoids
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• Study Design• Subjects exercised maximally with and
without ProArgi-9+ Active (Control)• Lactic acid was measured pre,
immediately, 15 min, and 30 min post exercise
• ProArgi-9+ Active was given 60 min before exercise in study
ProArgi-9+ Active HDHI Study
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ProArgi-9+ Active Results
Pre 0 mins 15 mins 30 mins0
20
40
60
80
100
120
control
Pro Active
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ProArgi-9+ Active ResultsSubject Control ProArgi-9+ Active
1 18 23
2 29 36
3 40 46
4 20 25
5 9 11
6 9 11
7 28 32
8 14 17
9 56 64
10 39 43
Endurance in min. 15% increase with ProArgi9+ Active
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ProArgi-9+ ActiveLow level exercise vs. High Intensity Exercise
control low pro active L control H pro active H
0102030405060708090
pre0 mins15min
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WE GET A D84% of patients Screened for Vitamin D3 were deficient:
• 18% < 10• 32% 10-20• 34% 21-29• N=1038
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WE GET A D• Average replacement instituted at HDHI 3500 units/day• Once target is attained( > 50 ng/dl )• Then maintenance dose: 2000-2500 units/day
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WE GET A D• BREAST HEALTH• COLON HEALTH• ANTIOXIDANT• BONE HEALTH• IMMUNE SYSTEM• CARDIOVASCULAR HEALTH