specifics of btk arterial disease in diabetic patients and … · direct revascularization...

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Marco Manzi, MD Interventional Radiology Unit Foot & Ankle Clinic Regional Center of Reference for the Treatment of Diabetic Foot Policlinico Abano, Abano Terme (PD) ITALY Specifics of BTK arterial disease in diabetic patients and implications for patient specific revascularisation strategies: Which is the right concept wound-related or total treatment?

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Page 1: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Marco Manzi, MD

Interventional Radiology UnitFoot & Ankle Clinic

Regional Center of Reference for theTreatment of Diabetic Foot

Policlinico Abano, Abano Terme (PD)ITALY

Specifics of BTK arterial

disease in diabetic patients and

implications for patient specific

revascularisation strategies:

Which is the right concept –

wound-related or total

treatment?

Page 2: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

•Abbott Vascular: Consultant

•Alvimedica: Consultant

•BARD: Consultant

•Boston SC: Consultant

•COOK: Consultant

•Medtronic-Invatec: Consultant

•Terumo: Consultant

DISCLOSURES:

Marco Manzi, MD

Page 3: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

1. Anatomical considerations

2. The angiosome as a target

3. Critics of the angiosome

concept

www.robertoferraresi.it

Anatomical Issues, Angiosomes and Wounds

Page 4: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound
Page 5: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Vascular abnormalities of ankle vessels distribution

Page 6: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

“Single” PER

artery

Anterior dominant

PER artery

Posterior dominant

PER artery

Distal distribution pattern:

3150 studied legs

Standard distribution:

“balanced circulation”

Anatomical

variations

2.4%

94.8%

1.9%

0.9%

5.2%

Page 7: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound
Page 8: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound
Page 9: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Vascular abnormalities of foot vessels distribution

Page 10: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Dominant dorsalis

pedis artery

Distal distribution pattern:

3150 studied legs

Standard distribution:

“balanced circulation”

Anatomical

variations

0.4%

79.1%

20.9%

Dominant lateral

plantar artery13.2%

Tarsal loop7.2%

Absence of the

pedal-plantar loop0.2%

Page 11: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Dominant dorsalis

pedis artery

Dominant lateral

plantar artery

Balanced

circulation

Page 12: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Every patient is different:

Follow patient’s anatomy

and not book pictures

Page 13: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

1. Anatomical considerations

2. The angiosome as a target

3. Critics of the angiosome

concept

www.robertoferraresi.it

Anatomical Issues, Angiosomes and Wounds

Page 14: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

2.

3.

1.

3 meta-analysis on the

angiosome guided

angioplasty

Page 15: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Direct revascularization

according to the

angiosome concept

seems to be better

compared with rev. in

terms of wound healing

and limb salvage

Page 16: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

1. Anatomical considerations

2. The angiosome as a target

3. Critics of the angiosome

concept

www.robertoferraresi.it

Anatomical Issues, Angiosomes and Wounds

Page 17: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

All of the studies

comparing direct and

indirect revascularization

are retrospective

It is possible that in the “indirect revascularization” groups there was a propensity to collect patients with the most technically challenging disease and the differences in the outcomes may simply reveal basal differences in the extension and type of obstructive disease

Page 18: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Try to do what is possible and don’t lose time on unrealistic targets!

www.robertoferraresi.it

All of the studies

comparing direct and

indirect revascularization

are retrospective

It is possible that in the “indirect revascularization” groups there was a propensity to collect patients with the most technically challenging disease and the differences in the outcomes may simply reveal basal differences in the extension and type of obstructive disease

Page 19: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

The value of an angiosome-oriented

revascularization is inversely related

to the function of collateral vessels

Page 20: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Troisi N, LINC 2016

The value of the PEDAL ARCH

Page 21: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Results: The wound(s) interfered with one angiosome in only 24.0% cases.

Conclusions: In CLI, the tissue lesion affects several angiosomesin the majority of the cases.

Page 22: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Open BTK vessels

Limbsalvage

0 56%1 better than 0

1 73%

2 80%2-3 better than 1

3 83%

PTA of tibial arteries had a better outcome than PTA of the peroneal artery alone

Page 23: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Extensive tissue damage cannot be

classified on the basis of an

angiosome-oriented scheme. In

these patients complete rev. better

than partial rev

Page 24: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Complex Lesion involving Bifurcations: Maintaining Good In-flow: focal

calficated lesion scaffolding

Page 25: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Angiosome Guided Sample

R.R.D.M., DyalisisCLI: non healing 2° toe amp; TUC 2c 1° and 3°

Page 26: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Revascularization Pattern Samples: Direct

Page 27: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Revascularization Pattern Samples: Direct

Page 28: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Revascularization Pattern Samples

Page 29: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

1. Try to do what is possible

and don’t lose time on

unrealistic targets!

2. Consider the rule of

collateral vessel

disease/function

3. Complete revascularization

is better than partial rev. in

Rutherford 6 pts (huge

wounds more than one

angiosome)

CONCLUSIONS

Thanks to R.Ferraresi

Page 30: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

THANKS FOR YOUR ATTENTION

Page 31: Specifics of BTK arterial disease in diabetic patients and … · Direct revascularization according to the angiosome concept seems to be better compared with rev. in terms of wound

Marco Manzi, MD

Interventional Radiology UnitFoot & Ankle Clinic

Regional Center of Reference for theTreatment of Diabetic Foot

Policlinico Abano, Abano Terme (PD)ITALY

Specifics of BTK arterial

disease in diabetic patients and

implications for patient specific

revascularisation strategies:

Which is the right concept –

wound-related or total

treatment?