synthesis and protection of aryl sulfates using the 2,2,2-trichloroethyl moiety
TRANSCRIPT
2004 Protection
ProtectionO 0345 Synthesis and Protection of Aryl Sulfates Using the 2,2,2-Trichloroethyl Moiety.
— The protecting group is introduced for the first time to phenolic hydroxyls. Depro-tection according to the methods shown in the scheme allows the preparation of sulfate monoesters.The methology is successfully applied to the construction of estrone sulfate derivatives (X) and (XI), which could not be prepared by previous methodologies. — (LIU, Y.; LIEN, I.--. F.; RUTTGAIZER, S.; DOVE, P.; TAYLOR, S. D.; Org. Lett. 6 (2004) 2, 209-212; Dep. Chem., Univ. Waterloo, Waterloo, Ont. N2L 3G1, Can.; Eng.) — Steudel
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2004 Protection