system workfl ow urinary tract infection (uti) cartridge
TRANSCRIPT
Working time 60 seconds
Working time 20 seconds
Working time 30 seconds
Transfer patient sample to Unyvero Sample Tube
Scanning and inserting the Unyvero Cartridge in the A50
(Max. 2 cartridges simultaneously)
Results displayed in Cockpit – PDF export
30 minutes lysis in Lysator
Assembling Unyvero Cartridge with Sample and Master Mix Tube
Panel Overview
System Workfl owUnyvero L4 Lysator Unyvero C8 Cockpit Unyvero A50 AnalyzerUnyvero L4 Lysator Unyvero C8 Cockpit Unyvero A50 Analyzer
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Curetis GmbH | Max-Eyth-Str. 42 | 71088 Holzgerlingen | GermanyTel.: +49 (0)7031 49195 10 | Email: [email protected] |
Unyvero is designed to expand with your growing needs
00299 Rev 8.0 © Curetis GmbH
Caution – Investigational Device. Limited by Federal US Law to investigational Use. Not available for Sale in the United States.
www.curetis.com
Blood Culture – BCU
Hospitalized Pneumonia – HPN
Implant & Tissue Infection – ITI
Intra-Abdominal Infection – IAI
Urinary Tract Infection – UTI
Urinary Tract Infection (UTI) Cartridge
Staphylococcus aureusCoagulase negative staphylococciStaphylococcus saprophyticusStreptococcus agalactiaeEnterococcus spp.Enterococcus faecalisEnterococcus faeciumCorynebacterium urealyticum
Gram-positive bacteria
EnterobacteriaceaeCitrobacter freundii / koseriKlebsiella aerogenes (E. aerogenes)Enterobacter cloacae complexEscherichia coliKlebsiella oxytocaKlebsiella pneumoniaeKlebsiella variicolaProteus spp.Providencia spp.
Enterobacteriales
Candida spp.Candida albicansCandida auris Candida glabrata
Fungi
GeneResistance
Acinetobacter baumannii complexPseudomonas aeruginosa
Non-fermenting bacteria
Detection of prokaryotic genetic sequence
Universal Bacteria
Bacteroides spp. / Prevotella spp.
Anaerobic bacteria
mecA
vanAvanB
ctx-M
impkpcndmoxa-23oxa-24/40oxa-48vim
mcr-1
qnrBqnrS
sul1
3rd generation Cephalosporins
Glycopeptides
Fluoroquinolones
Sulfonamide
Carbapenem
Polypeptides / polymyxins
Oxacillin
Urine (mid-stream, suprapubic, fresh catheter) and tissue.
Sample Types
*88 Pathogens, 15 Resistance Genes
4 to 5 hour analysis process
103*
Staphylococcus aureusCoagulase negative staphylococciStreptococcus spp. Streptococcus agalactiaeStreptococcus pneumoniaeStreptococcus pyogenes / dysgalactiaeEnterococcus spp.Enterococcus faecalisListeria monocytogenes
Gram-positive bacteria
Staphylococcus aureusCoagulase negative staphylococci Streptococcus spp. Streptococcus agalactiaeStreptococcus pneumoniaeStreptococcus pyogenes /dysgalactiaeGranulicatella adiacensAbiotrophia defectivaEnterococcus spp. Enterococcus faecalis
Gram-positive bacteria
Coagulase negative staphylococciEnterococcus faecalisEnterococcus spp.Streptococcus spp.Staphylococcus aureus
Gram-positive bacteria
Staphylococcus aureusStreptococcus pneumoniae
Gram-positive bacteria
Citrobacter freundii / koseriEscherichia coliEnterobacter cloacae complexKlebsiella aerogenes (E. aerogenes)Klebsiella oxytocaKlebsiella pneumoniaeKlebsiella variicolaProteus spp. Serratia marcescens
Enterobacteriales
Corynebacterium spp.
Citrobacter freundii / koseriEscherichia coliEnterobacter cloacae complex Klebsiella aerogenes (E. aerogenes)Klebsiella pneumoniaeKlebsiella oxytocaKlebsiella variicolaProteus spp.
Detection of prokaryotic genetic sequence
Citrobacter freundiiEscherichia coliEnterobacter cloacae complexKlebsiella aerogenes (E. aerogenes)Proteus spp.Klebsiella pneumoniaeKlebsiella oxytocaKlebsiella variicolaSerratia marcescensMorganella morganii
Corynebacteriaceae
Enterobacteriales
Universal Bacteria
Enterobacteriales
Aspergillus spp.Candida spp.Candida albicansCandida dubliniensisCandida glabrataI. orientalis (C. krusei)Candida parapsilosisCandida tropicalis
Candida spp.Candida albicansCandida glabrataI.orientalis (C.krusei)Candida tropicalis
Candida spp.Candida albicansCandida glabrataCandida tropicalisIssatchenkia orientalis (Candida krusei)
Fungi Fungi
Fungi
GeneResistance
aac(6´)/aph(2´´) aacA4
ermA
mecA mecC
vanA vanB
ctx-M
imp kpc ndm oxa-23 oxa-24/40 oxa-48 oxa-58 vim
3rd generation Cephalosporins
Carbapenem
Macrolide/ Lincosamide
Oxacillin
Glycopeptides
Aminoglycoside
Gene
Gene
Resistance
Resistance
GeneResistance
Acinetobacter baumannii complexPseudomonas aeruginosaStenotrophomonas maltophilia
Acinetobacter baumannii complexPseudomonas aeruginosa
Moraxella catarrhalisPseudomonas aeruginosaAcinetobacter baumannii complexStenotrophomonas maltophiliaLegionella pneumophilaNon-fermenting bacteria
Non-fermenting bacteria
Non-fermenting bacteria
Detection of prokaryotic genetic sequence
Universal Bacteria
Haemophilus influenzaeNeisseria meningitidis
Corynebacterium spp.
Acinetobacter baumannii complexPseudomonas aeruginosa
Detection of prokaryotic genetic sequence
Escherichia coliKlebsiella aerogenes (E. aerogenes) Enterobacter cloacae complex Klebsiella pneumoniae Klebsiella oxytocaKlebsiella variicola Proteus spp.Other Gram-negative
bacteria
Corynebacteriaceae
Non-fermentingbacteria
Universal Bacteria
Enterobacteriales
Mycobacterium spp.
Mycobacteriaceae
Cutibacterium acnes (P. acnes)
Cutibacterium acnes (P. acnes)
Finegoldia magna
Bacteroides fragilis group
Aeromonas spp.
Bacteroides fragilis group
Bacteroides spp. / Prevotella spp.
Clostridioides difficile (C. difficile)
Clostridium perfringens
Finegoldia magna
Cutibacterium acnes (P. acnes)
Pneumocystis jirovecii
Haemophilus influenzae
Mycoplasma pneumoniae
Chlamydia (Chlamydophila)pneumoniae
Anaerobic bacteriaAnaerobic bacteria
Anaerobic/facultativeanaerobic bacteria
Others/Fungi
Blood Culture (BCU) Cartridge Hospitalized Pneumonia (HPN) Cartridge Implant & Tissue Infection (ITI) Cartridge Intra-Abdominal Infection (IAI) Cartridge
ermB
mecA mecCtem shv
ctx-M
imp kpc ndm oxa-23 oxa-24/40 oxa-48 oxa-58 vimsul1gyrA83 gyrA87
Oxacillin
Penicillin
Carbapenem
Sulfonamide
Fluoroquinolone
3rd generation Cephalosporins
Macrolide/Lincosamide
Oxacillin
Aminoglycoside
Carbapenem
Glycopeptides
3rd generation Cephalosporins
Macrolide/Lincosamide
ermA ermC
aac(6´)/aph(2´´) aacA4
mecA mecC
vanA vanB
ctx-M
imp kpc ndm oxa-23 oxa-24/40 oxa-48 oxa-58 vim
MarkerToxin
Shiga Toxin stx1/2
Toxin B tcdB
mecA mecC vanA vanB aacA4
ctx-M
fosA3
mcr-1
nimA nimB qnrA qnrB qnrS tetA imp kpc ndm oxa-23 oxa-24/40 oxa-48 oxa-58 vim
Glycopeptides
Aminoglycoside
Tetracycline
Carbapenem
FosfomycinPolypeptides/polymyxins
Nitroimidazole
Fluoroquinolone
3rd generation Cephalosporins
Oxacillin
Ascites and peritoneal fluid, pancreatic juice, bile, tissue, puncture fluid,swabs, catheter/drainage tips, and samples from positive blood culturebottles that have been inoculated with ascites/puncture fluid.
Sonication fluids, swabs, tissue, pus, aspirate/exudate, bone fragments, etc.Sputum, bronchoalveolar lavage, tracheal aspiratesPositively flagged blood cultures
Sample Types Sample Types Sample Types Sample Types
*105 Pathogens, 3 Toxins, 22 Resistance Genes*85 Pathogens, 17 Resistance Genes*86 Pathogens, 17 Resistance Genes *29 Pathogens, 19 Resistance Genes
103* 102* 130*48*