the biomedical informatics research network carl kesselman birn principal investigator professor of...

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The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences Institute Fellow Viterbi School of Engineering

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Page 1: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

The Biomedical Informatics Research Network

Carl KesselmanBIRN Principal Investigator

Professor of Industrial and Systems Engineering

Information Sciences Institute Fellow

Viterbi School of EngineeringUniversity of Southern California

Page 2: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

Biomedical Informatics Research Network

• Infrastructure and services to support collaborative biomedical research

• Established by NCRR in 2001• Restructured in 2008

Page 3: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

BIRN History• 3 Distributed Test beds

(Neuroscience/Neuroimaging Drivers)– Mouse, High Resolution Imaging and Animal Models of Human Diseases (Toga, UCLA)

– Morph, Brain Structure in AD, Mild Cognitive Impairment, Depression (Rosen, MGH)

– Function, Activation Differences in Schizophrenia (Potkin, UCI)

• BIRN IT Coordinating Center (Ellisman, UCSD)• Distributed hardware with defined, evolving

software on identical machines• Centralized/BIRN-wide services• BIRN “Portal”

Page 4: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

BIRN Executive CommitteeBIRN Executive Committee

Steering CommitteeSteering CommitteeNew and Existing

Users/CollaboratorsNew and Existing

Users/CollaboratorsCommunity

OutreachCommunity

Outreach

Working GroupsWorking Groups

BIRN CC Functions

InfrastructureCommunication

Personnel

BIRN CC Functions

InfrastructureCommunication

Personnel

Data ManagementData Management Information IntegrationInformation Integration

Knowledge EngineeringKnowledge Engineering OperationsOperations

SecuritySecurity

BIRN Administrative Structure

Page 5: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

BIRN Approach

• Integrated Activity supported through 2 Cooperative Agreements (2008)• Coordinating Center – Kesselman, USC/ISI• Collaborative Tools Service Network – Rosen, MGH

• Customized solutions for collaborating groups

• Capabilities – defined in terms of user needs– Tools, Services, Expertise

• Layered architecture allows BIRN capabilities to be incorporated into the existing technology of the end user.

Page 6: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

Engagement Model

• Contact with members of domain science collaborative group

• Define a Use Case• Identify a driving need with well-defined goals

• Technical staff to construct and maintain the network

• Buy-in from the community• Work with BIRN to develop a solution• Integrate existing tools and services with BIRN• Result is a customized, evolving infrastructure system

Page 7: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

BIRN Approach• Use-case driven requirements, bottom up design

• Well defined roadmaps, features, functions• Follow capabilities approach from TeraGrid– Promote reuse across communities

• Move to software and services model– BIRN not defined by the “rack”

• Outreach to new communities– More than the testbeds

Page 8: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

Technical Approach

• Bottom up, not top down• Focus on user requirements, what they want to do

• Create solutions, factor out common requirements– Capability model includes software and process

– Avoid “Big Design up Front” (BDUF)

Page 9: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

Form of the Meeting

• Part One– detailed talks on five ongoing BIRN collaborations

– chosen to show how collaborative work could be of use your institute

• Part Two– quick summaries of new and emerging capabilities

• Questions welcome– At the end of each presentation, we can field a few questions.

Page 10: The Biomedical Informatics Research Network Carl Kesselman BIRN Principal Investigator Professor of Industrial and Systems Engineering Information Sciences

Interested to follow up?

• Contact us:– Carl Kesselman: [email protected]– Joe Ames: [email protected]– Karl Helmer: [email protected]

• BIRN Website: www.birncommunity.org