the digital pathology archive: the umc utrecht initiative paul van diest, md, phd professor and head...

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The digital pathology The digital pathology archive: the UMC Utrecht archive: the UMC Utrecht initiative initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center Utrecht [email protected]

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Page 1: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

The digital pathology archive: the UMC The digital pathology archive: the UMC Utrecht initiativeUtrecht initiative

Paul van Diest, MD, PhDProfessor and HeadDepartment of PathologyUniversity Medical Center [email protected]

Page 2: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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The problem IThe problem I

•100.000 new slides per year• archive of 7.000.000 slides• total weight 60.000 kg• weight increase 100 kg per year

Page 3: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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The problem IIThe problem II

• slides often have to be retrieved:

• clinicopathological conferences• compare with new material• teaching• research

Page 4: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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The problem IIIThe problem III

• slide retrieval takes time (0.5 fte)• many circulating slides• slides may get lost/misplaced• slide quality deteriorates in time

• faded colors• loose cover glasses• broken

Page 5: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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The solution?The solution?

• technically feasible to digitize all slides

• store images on SAN

• view slides digitally

Page 6: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Advantages of the digital archiveAdvantages of the digital archive

• all slides are digitally available • instantaneously • simultaneously to multiple users

• no slide retrieval from the archive• no searching for circulating slides• constant image quality• no slides get lost/damaged

Page 7: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Advantages of the digital archiveAdvantages of the digital archive

• quicker preparation of CP conferences• CP can be held outside the pathology laboratory• close colleagues can be consulted quicker• remote colleagues (at home, at conferences,

on vacation) can be consulted quicker• external consultations can be done quicker• images can be made available in EPF (ZIS, Mirador)

Page 8: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Advantages of digital “microscopy” Advantages of digital “microscopy” teachingteaching

• all students view the same “best slide”• slide images can be integrated with

• annotations• questions• macroscopic images• sound clips• links• etc

Page 9: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Advantages of the digital archiveAdvantages of the digital archive

• more efficient CP conferences• higher speed, dynamics and flexibility of consultation• higher quality and more dynamic teaching

but……

Can it be done?

Page 10: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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The digital pathology archive: the UMC Utrecht The digital pathology archive: the UMC Utrecht solutionsolution

RVC

scanning

database

storage

120 TB tape library 6 TB fast access hard disk array

order form scanner

macro imager

pathology users clinical users

DPS

mirador

HSM

acquisitionworkstation

Sun SAN

Page 11: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Digital slide demoDigital slide demo

Page 12: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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PALGA linkPALGA link

Page 13: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Pitfalls of the digital archive IPitfalls of the digital archive I

• huge storage management • 200 MB – 1 GB per slide (20x)• 80 TB per year

• backup• back archive• speed of image retrieval• logistics of scanning 500 slides per day• no delay in having slides scanned• flexible scanning slots • image compression

Page 14: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Pitfalls of the digital archive IIPitfalls of the digital archive II

• costs (vs. savings/quality improvement)

0

10

20

30

40

50

60

1 3 5 7 9 11 13 15

costs

Page 15: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Scanning logisticsScanning logistics

• scanners are loaded twice daily• at different moments• organize other work around this• 7 hours per run• bar code recognition in scanners• extra set of slide boxes • mark slides to be scanned (double slides)• do not write on slides• install alarm system when scanner crashes

Page 16: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Future perspectives IFuture perspectives I

• nationwide digital archive (EPF)• quicker revision• quicker consultation

lab A

lab Blab C

lab D

lab E

lab I

lab H

lab G lab F

lab A

lab Blab C

lab D

lab E

lab I

lab H

lab G lab F

centralstorage

or…

Page 17: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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Future perspectives IIFuture perspectives II

• digital diagnostics

• remote diagnostics

• diagnostic networks

Page 19: The digital pathology archive: the UMC Utrecht initiative Paul van Diest, MD, PhD Professor and Head Department of Pathology University Medical Center

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The digital pathology archive:The digital pathology archive:

desirable and feasible!desirable and feasible!