the nervous system presents: pain in association with tanya and stefan
TRANSCRIPT
Introduction
The nervous system is the system of cells, tissues, and organs that regulates the body's responses to internal and external stimuli.
It is composed of the brain, spinal cord and nerves.
Nerves are bundles of happiness neurons.
The Neuron Family
A neuron is a nerve cell. It is electrically excitable, and thus processes and transmits information by electrical and chemical signals. There are three types of neurons in the human body.
How Do They Work?
Information is conveyed through the nervous system as nerve impulses.
These impulses travel from neuron to neuron via a junction called a synapse Release chemicals called
neurotransmitters Neurotransmitter molecules cross the
synapse and stimulate the next neuron to fire an impulse of its own
Action Potential
The nerve impulses are also known as action potentials
The impulse is based on movement of positively charged Na+ and K+ ions through the cell membrane
Three states of the axon as the nerve impulse passes through it: Resting Potential Depolarization Repolarization
The Big Picture
Stimulus causes action potential at pain receptors
AP travels to dorsal horn in the spinal cord through
afferent neurons
Afferent Neurons
Dorsal Horn
Efferent Neurons
Directs nerve impulses to the brain as well as the
affected area via efferent neurons
Visual Components
Neurons Sensory Neurons Motor Neurons Interneurons Neuron Parts:
Cell Body (Soma) Axon
Schwann Cells Myelin Sheath
Axon Terminal Dendrites
Skin cells
Synapse Neurotransmitters Synaptic Vesicles Ion Channels Receptors Pumps
Spinal Cord Bundle of Axons Epidural Space
Stimulus
The Polysynaptic Reflex to Pain
Stimulus Nociceptors
Motor Neurons
DorsalHorn
SensoryNeurons
Brain
Relevant Muscles
Instant
Canada’s Next TOP Model
Will be modeled using agent based modeling
Animations used for ion channel transfer
Impulse will be propagated through ion movement
Level of detail: No mitochondria and neurotubules, when NT are in synaptic vesicles, they will not be
individually packed into the vesicle but represented as a single entity, then in the synaptic space divided into multiple objects
Computational Components
Time will be slowed down as impulses move too fast to be perceived
Axon will light up in the area the impulse travels through
Sensory Adaptation Shows a decrease in sensitivity during continued stimulation
Adjustable parameters for the stimulus Amount and Time stimulus is applied
Adjustable parameters for the addition of painkillers into the model
Possible graphs to support the model Action Potential
Interactions with brain will be kept to a minimum
Sources
Freudenrich, C. (2010). How Your Brain Works. Retrieved August 5, 2010, from How Stuff Works: http://health.howstuffworks.com/human-body/systems/nervous-system/brain2.htm
Jacques, E. (2009, July 21). How We Feel Pain. Retrieved August 5, 2010, from About.com: http://pain.about.com/od/whatischronicpain/a/feeling_pain.htm
Kapit, W., Macey, R. I., & Meisami, E. (2000). The Physiology Coloring Book. San Francisco, CA, US: Addison Wesley Longman, Inc.
Parker, S. (2009). The Concise Human Body Book. Toronto, ON, Canada: Dorling Kindersley.
Unknown. (n.d.). Nervous System. Retrieved August 5, 2010, from Web-Books: http://www.web-books.com/eLibrary/Medicine/Physiology/Nervous/Nervous.htm