the present evolution of liver transplantation in europe
DESCRIPTION
The Present Evolution of Liver Transplantation in Europe. EUROPEAN LIVER TRANSPLANT REGISTRY. 28 countries - 153 institutions 113,627 transplantations - 102,442 patients From May 1968 to December 2012. www.eltr.org. The Present Evolution of Liver Transplantation. - PowerPoint PPT PresentationTRANSCRIPT
12/2013
The Present Evolution of Liver Transplantation in EuropeEUROPEAN LIVER TRANSPLANT REGISTRY
28 countries - 155 institutions118,441 transplantations - 106,849 patients
From May 1968 to December 2013
www.eltr.org
12/2013
The Present Evolution of Liver Transplantation
1. General evolution of LT in Europe
2. Donor data
3. Recipient data
4. Indications and results
5. Evolution of techniques
6. Mortality and retransplantation
12/2013
The Present Evolution of Liver Transplantation
1. General evolution of LT in Europe
2. Donor data
3. Recipient data
4. Indications and results
5. Evolution of techniques
6. Mortality and retransplantation
12/2013
EUROPEAN LIVER TRANSPLANT REGISTRY28 countries - 155 institutions
118,441 transplantations - 106,849 patientsFrom May 1968 to December 2013
781
2441
4963
1526
1002
21279
15923
16487
557
829
14354
11
2447
1127
2272
2033
500178
20318
2748
1901
4214
1672
42
229
47
162
12/2013
Evolution of 118,364 Liver Transplantations in Europe
* The decrease is owed to the fact that some centers had a delay in the updating of their data to the current development of a new data reporting system,
*
12/2013Evolution of the number of Liver
Transplantations reported to the ELTR
200
300
400
500
600
700
800
900
1000
1100
1200
FRANCE : 19191 GERMANY : 14827GREAT BRITAIN : 14832 SPAIN : 19948ITALY : 13459
(No LT)
12/2013
Evolution of the number of Liver Transplantations by Center
0
20
40
60
80
100
120
FRANCE : 17098 GERMANY : 13237GREAT BRITAIN : 13470 SPAIN : 16692ITALY : 12963
(No LT / Center)
12/2013
The Present Evolution of Liver Transplantation
1. General evolution of LT in Europe
2. Donor data
3. Recipient data
4. Indications and results
5. Evolution of techniques
6. Mortality and retransplantation
12/2013Evolution of Donor Age05/1968 – 12/2013
12/2013
Gender and Age distribution of Liver Donors
01/1988 - 12/2013
12/2013
Graft Survival according to Donor Age in Europe
01/1988 - 12/2013
12/2013
Graft Survival according to Donor Agein Elective Liver Transplantation
01/1988 – 12/2013
12/2013
Graft Survival according to Donor Agein Urgent Liver Transplantation
01/1988 - 12/2013
12/2013
The Present Evolution of Liver Transplantation
1. General evolution of LT in Europe
2. Donor data
3. Recipient data
4. Indications and results
5. Evolution of techniques
6. Mortality and retransplantation
12/2013Age and Sex of Recipients
05/1968 – 12/2013
12/2013Evolution of Recipient Age05/1968 – 12/2013
12/2013
Patient Survival according to Recipient Age
01/1988 - 12/2013
p Log Rank = 0.0001
12/2013
Patient Survival according to Adult Recipient Age
01/1988 - 12/2013
12/2013
Proportion of Pediatric Transplantation by Country 01/1988 - 12/2013
12/2013Primary Indication of Liver
Transplantation in Pediatric Patients05/1968 - 12/2013
12/2013Survival according to Children Recipient Age
01/1988 - 12/2013
Patient Graft
12/2013
Survival of Children < 2 yrs according to the Main Indication in Europe
01/1988 - 12/2013
12/2013
Survival of Children >= 2 yrs according to the Main Indication in Europe
01/1988 - 12/2013
12/2013
Graft Survival according to Adult Recipient Age01/1988 - 12/2013
12/2013
Primary Indications of Liver Transplantion in Elderly Patients (>= 60 Years)
01/1988 - 12/2013
12/2013
Survival of Elderly Recipients (>= 60 Years) according to the Main Indication in Europe
01/1988 - 12/2013
12/2013
The Present Evolution of Liver Transplantation
1. General evolution of LT in Europe
2. Donor data
3. Recipient data
4. Indications and results
5. Evolution of techniques
6. Mortality and retransplantation
12/2013
* Others : Budd Chiari : 869 Benign liver tumors or Polycystic diseases : 1334Parasitic diseases : 84 Other liver diseases : 2047
Primary Diseases leading to Liver Transplantion in Europe
01/1988 - 12/2013
12/2013
Primary Indications of Liver Transplantion in Europe
01/1988 - 12/2013
12/2013
Evolution of Primary Diseases leading to Liver Transplantation in Europe
05/1968 - 12/2013
12/2013
Primary Diseases leading to Liver Transplantion by Country
01/1988 - 12/2013
12/2013
Primary Diseases leading to Liver Transplantation in Adult Recipients
01/1988 - 12/2013
12/2013
Patient and Graft Survival following Liver Transplantation
05/1968 – 12/2013
12/2013
Patient Survival according to the Year of Liver Transplantation
05/1968 – 12/2013
12/2013
Patient Survival according to the Indication01/1988 - 12/2013
12/2013
Patient Survival according to the 1st Indication
01/1988 – 12/2013
12/2013
Graft Survival according to the Urgency of Liver Transplantation
in Europe01/1988 - 12/2013
12/2013Graft Survival according to ABO
Compatibility in Elective Liver Transplantation01/1988 - 12/2013
12/2013
Graft Survival according to ABO Compatibility in Urgent LT
01/1988 - 12/2013
12/2013Liver Transplantation in Europe
Indications of Cirrhosis01/1988 - 12/2013
12/2013
Evolution of Indications for Cirrhosisin Europe
12/2013
Survival of Patients with Cirrhosisas the First Indication (1)
01/1988 - 12/2013
12/2013
Survival of Patients with Cirrhosisas the First Indication (2)
01/1988 - 12/2013
12/2013
Primary Indications of Liver TransplantationFor Virus related Cirrhosis in Europe
01/1988 - 12/2013
12/2013
Survival of Patients with Virus related Cirrhosis as the First Indication
01/1988 - 12/2013
12/2013
Survival of Patients with Virus related Cirrhosis as the First Indication
01/1988 - 12/2013
12/2013
Survival of Patients with Virus related Cirrhosis as the First Indication
01/1988 - 12/2013
12/2013Liver Transplantation in Europe
Indications in Hepato-Biliary Cancers01/1988 - 12/2013
Others: Hepatoblastoma: 261Epithelioid hemangioendothelioma: 186Angiosarcoma: 20
12/2013
Evolution of Indications for Hepato-BiliaryCancers in Europe
05/1968 - 12/2013
12/2013
Survival of Patients with Liver Canceras the First Indication
01/1988 - 12/2013
12/2013
Survival of Patients with HCC with and without underlying Cirrhosis
01/1988 - 12/2013
12/2013Primary Indications of Liver Transplantation
In Patients with Acute Hepatic Failure01/1988 - 12/2013
12/2013
Survival of Patients with Acute Hepatic Failure as the First Indication
01/1988 - 12/2013
12/2013
Primary Indications of Liver Transplantationin Patients with Cholestatic Diseases
01/1988 - 12/2013
12/2013
Survival of Patients with Cholestatic Diseases as the First Indication
01/1988 - 12/2013
12/2013
Primary Indications of Liver Transplantationin Patients with Metabolic Diseases
01/1988 - 12/2013
12/2013
Survival of Patients with Metabolic Diseases as the First Indication
01/1988 - 12/2013
12/2013
Indications of Liver Transplantation for Other liver diseases in Europe
05/1968 - 12/2013
12/2013
Survival of Patients with Other Liver Diseases as the First Indication
01/1988 - 12/2013
12/2013
The Present Evolution of Liver Transplantation
1. General evolution of LT in Europe
2. Donor data
3. Recipient data
4. Indications and results
5. Evolution of techniques
6. Mortality and retransplantation
12/2013
Recipient age Full size Reduced Split liver DominoLiving Donor
0 to 2 969 755 1534 5 12662 to 15 2747 899 1522 4 86615 to 45 25559 232 1061 98 136245 to 60 46603 137 1460 404 2006≥60 19621 49 627 360 724Total 95499 2072 6204 871 6224
Type of Liver Graft according to Recipient Age 01/1988 - 12/2013
12/2013
Graft Survival in Liver Transplantation only vs Liver Combined to other Organ Transplantation
01/1988 - 12/2013
12/2013
Graft Survival according to the Site of Transplantation in Elective LT
01/1988 - 12/2013
12/2013Type of Liver Graft in Europe
according to the Date of Transplantation
12/2013
Graft Survival according to the Type of Graft
01/1988 - 12/2013
12/2013Alternatives to the Use of the Full
SizeCadaveric Liver Grafts in Europe
12/2013
Graft Survival according to the Type of Graft 01/1988 - 12/2013
12/2013
Graft Survival according to the Type of Graft in Elective LT
01/1988 - 12/2013
12/2013
Graft Survival according to the Type of Graft in Urgent LT
01/1988 - 12/2013
12/2013
Graft Survival according to the Cold Ischemic Time in UW Elective LT
01/1988 - 12/2013
12/2013
Graft Survival according to the Cold Ischemic Time in UW Urgent LT
01/1988 - 12/2013
12/2013
Auxiliary vs Non Auxiliary Graft Survival in Elective Liver Transplantation
01/1988 - 12/2013
12/2013
Auxiliary vs Non Auxiliary Graft Survival in Urgent Liver Transplantation
01/1988 - 12/2013
12/2013The Present Evolution of Liver
Transplantation
1. General evolution of LT in Europe
2. Donor data
3. Recipient data
4. Indications and results
5. Evolution of techniques
6. Mortality and retransplantation
12/2013
Liver Transplantation in EuropeMortality and Retransplantation
01/1988 - 12/2013
12/2013
Mortality and RetransplantationAccording to Recipient Age
01/1988 - 12/2013
12/2013
Mortality and RetransplantationAccording to the 1st Indication
01/1988 - 12/2013
12/2013
Graft Survival according to the Number of Liver Transplantations in Europe
01/1988 - 12/2013
12/2013
Graft Survival according to the number of the LT in Elective Cases
01/1988 - 12/2013
12/2013
Graft Survival according to the number of the LT in Urgent Cases
01/1988 - 12/2013
12/2013
Patient Survival according to the number of Liver Transplantations
01/1988 - 12/2013
12/2013
Patient Survival according to the number of LTs in Elective cases for the 1st LT
01/1988 - 12/2013
12/2013
Patient Survival according to the number of LTs in Urgent cases for the 1st LT
01/1988 – 12/2013
12/2013
Mortality following the 1st LT 01/1988 - 12/2013
12/2013
Causes of Retransplant following the 1st LT01/1988 - 12/2013
12/2013
ELTR Coordination Committee
René Adam, MD, PhD.Custodian
Vincent Karam, PhD.Data Manager
Valérie Delvart, MA.Biostatistician
Anne-Marie LammerantSecretary
European Liver Transplant RegistryHôpital Paul BrousseCentre Hépatobiliaire12 Avenue Paul Vaillant Couturier94804 Villejuif, France
Tel. +33 1 45 59 38 28www,eltr.org
12/2013
the support of:
The ELTR continue to evolve thanks to the participation of the 153 centers and to:
the colaboration with: