the use of p-values and bayes factors in genome- wide association studies professor jon wakefield

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The Use of The Use of p p -values and -values and Bayes Factors in Genome- Bayes Factors in Genome- Wide Association Studies Wide Association Studies Professor Jon Wakefield Professor Jon Wakefield

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Page 1: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

The Use of The Use of pp-values and Bayes -values and Bayes Factors in Genome-Wide Factors in Genome-Wide

Association StudiesAssociation Studies

Professor Jon WakefieldProfessor Jon Wakefield

Page 2: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

The Use of The Use of pp-values and Bayes -values and Bayes Factors in Genome-Wide Factors in Genome-Wide

Association StudiesAssociation Studies

Professor Jon WakefieldProfessor Jon Wakefield“Bayesian God”

Page 3: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – career progression– career progression

Chair ISBA (read paper)

IISSBBA!A!Modeling

Page 4: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – distinguished (easily) – distinguished (easily)

• Hair

• Glasses

• Accent

Page 5: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – distinguished (easily) – distinguished (easily)

• Hair

• Glasses

• Accent

Page 6: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – distinguished (easily) – distinguished (easily)

• Hair

• Glasses

• Accent

Page 7: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – influential figures– influential figures

• Patrick Heagerty (hair, hat)

• Uncertaindirection?

• Finallyinto gear!

Page 8: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – influential figures– influential figures

• Patrick Heagerty (hair, hat)

• Uncertaindirection?

• Finallyinto gear!

Page 9: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – influential figures– influential figures

• Dr D Balding

• Now headsimperial group

• “Laser-like”

Page 10: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – influential figures– influential figures

• Dr E (Balding)

• Now headsimperial group

• Likes “Lasers”

Page 11: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – influential figures– influential figures

• Lead his field

• A ‘colorful’ character

Page 12: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – influential figures– influential figures

• Lead his field

• A ‘colorful’ character

Page 13: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – a family man– a family man

Looks more like…

Him in miniature!

?

Page 14: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – a family man– a family man

Looks more like…

Him in miniature!

?

Page 15: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – a statistical rock star!– a statistical rock star!

• Performed several unusual acts in Kensington

Page 16: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

Jon Wakefield Jon Wakefield – a statistical rock star!– a statistical rock star!

• Performed several unusual acts in Kensington!

Page 17: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

The Use of The Use of pp-values and Bayes -values and Bayes Factors in Genome-Wide Factors in Genome-Wide

Association StudiesAssociation Studies

Professor Jon WakefieldProfessor Jon Wakefield

Page 18: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield

professor jon professor jon WakefieldWakefield