the wassermann test in general practice

1
546 physical treatment is more fully recognised than in this country, the number of cases of marked scoliosis is comparatively rare and severe cases still rarer. It is impossible to judge as yet whether this is the triumph and vindication of preventive treatment or not, but the presumption is that we, in this country, lag behind. This is not due to lack of effort, but the discussion showed that much of this effort is mis- directed. At the conclusion of the discussion it was proposed, from the chair, that the Council of the Society of Massage and Medical Gymnastics be approached to form a committee to discuss the whole subject with representative medical men. This conference will be charged to estimate what is good and what is bad in our present management of these cases ; what physical treatment can accomplish as a curative, palliative, or preventive agency; how z’ much of the training of the medical gymnast is faulty, both from the view of excess and omission; and what can be done to secure better cooperation between medical men and the gymnasts to whom they depute their treatment. It is to be hoped that represen- tatives of the Ling Association may also be invited to join in this conference, which, if successful, should prove of high value. _____ KING EDWARD VII. SANATORIUM, MIDHURST. THIS sanatorium was founded by H.M. King Edward VII. in 1903, with funds provided by the late Sir Ernest Cassel, part of which were reserved for endowment. It was built expressly for educated persons of limited means who are suffering from pulmonary tuberculosis in an early stage. The Council, we are informed, believe that there are many individuals in the above class who do not avail themselves of the benefits of the institution, because their medical advisers are not aware of the unique advantages which it presents ; and it is felt to be very desirable to enlist the cooperation of such prac- titioners, whose knowledge of their patients will enable them to select the person3 socially as well as physically suitable for admission. The advantages of site, environ- ment, building, and equipment of the sanatorium, which is placed in one of the loveliest parts of Sussex, are probably well known to our readers. The medical attendance and nursing organisation is thorough and efficient for an establishment of 104 beds. It consists of a medical superintendent, two assistant medical officers, a pathologist, and a visiting dental surgeon, while the institution is supervised by a consulting staff of London physicians, who visit it with regularity. Our readers should also note that a report of the condition of each patient on admission and on discharge is sent to the medical man concerned in the case, who also receives the annual report of the work of the institution. The inclusive charge for maintenance and treatment is at present 4t guineas weekly. Applica- tion for admission should be made to the Medical Superintendent, King Edward VII. Sanatorium, Mid- hurst, Sussex, who will forward all particulars. THE WASSERMANN TEST IN GENERAL PRACTICE. To what extent are modern laboratory tests made use of in general practice ? Much depends on the scientific keenness of the practitioner. We imagine that in almost every case of suspected phthisis a specimen of sputum is subjected to a bacteriological examination, either by the practitioner himself or in some laboratory. But with that exception it is questionable if full use is made of laboratory facilities. The statistical returns made by public laboratories up and down the country do not, for instance, suggest that the general practitioner sends many specimens to be examined either for the gonococcus or the spironema of syphilis. It may be, of course, that, with centralisation of treatment in the free venereal clinics, the general practitioner is seeing less and less of these diseases, and therefore does not need labora- tory aid for their diagnosis. But he must come across many cases of obscure disease in which an examination of the blood by the Wassermann test would be of assistance in helping him to a diagnosis. While it cannot be too often emphasised that a positive result from the Wassermann test does not necessarilv mean that the immediate affection from which a, patient is suffering must be syphilitic-the result of the test must be weighed carefully along with all the clinical symptoms and the details of the patient’s history-nevertheless the result of the Wassermann test may be the determining factor in leading the practitioner to a correct conclusion. These remarks are suggested by an interesting article in the January number of the Edinburgh Medical Journal by Dr. Arthur Mills, of Dundee, on the Wassermann Test in General Practice. Dr. Mills points out a fact that is daily becoming more and more appreciated by all hospital surgeons-viz., that a child may be suffering from hereditary syphilis without exhibiting any of the classical stigmata of that disease. He further shows that inherited syphilis may manifest itself in a variety of conditions which have not been hitherto recognised as depending upon hereditary infection, but which yield rapidly to antiluetic treatment. From his experience in general practice, where he seems wisely to have lost no opportunity of having the blood of his patients subjected to the Wassermann test whenever he deemed it necessary, he has gathered a valuable collection of suggestive facts. His observations indicate that all family physicians would be well advised to make fre- quent use of the serological examination. Its result may prove as valuable an aid to them as it has to him, and enable them to decide upon a correct line of treatment in cases where, but for the laboratory test, the precise diagnosis would have been uncertain. The perusal of Dr. Mills’s article will repay all practitioners, and be of profit to more than one specialist. HOLES IN THE MACULA. THE condition known as " hole in the macula is one of the rarer results of a blow on the eye. Occasion- ally it is found in the course of disease ; F. A. Williamson-Noble,1 making a pathological examination of an eye excised for absolute glaucoma secondary to- thrombosis of the central vein, has found this con- dition. A cyst had been formed at the macula between retina and choroid and the retinal layers overlying this. cyst had completely atrophied. The condition was, attributed to a toxic influence acting on the macular choroidal capillaries and causing oedema. Then, according to Williamson-Noble, the fluid diffuses into the potential space between the rods and cones and the pigment epithelium, preventing the access of nutrient materials from the chorio-capillaris, so that the superjacent retina degenerates and forms a hole. Can traumatic cases be similarly explained ? Accord- ing to Menteith Ogilvie, who made a collection of these cases in 1900,2 the injury is the result of " contrecoup,’ the waves of force initiated by the blow on the front of the eye meeting at the posterior pole. Williamson- Noble suggests that the effect of this may be to- cause oedema, with cyst formation and the appear- ance of a hole just as in non-traumatic cases. A unique case is reported from China by T. M. Li, of Pekin, 3 in which not one but both eyes were similarly affected. The patient was a soldier of 22 and received the injury when playing football, being struck fairly in the face by the ball and made unconscious for about ten minutes. Typical holes in each macula were found, with poor vision and relative central scotomata. The condition subsequently improved. The ophthalmo- scopic picture of these cases is very striking and is well represented in the papers already quoted by Ogilvie and Li. Its distinguishing feature is a round or oval area at the macula, cherry-red in colour, as. in cases of simple retinal oedema, but, unlike these, sharply defined and on a deeper level than the adjoining fundus. 1 British Journal of Ophthalmology, February, 1922. 2 Trans. Oph. Society, vol. xx. 3 American Journal of Ophthalmology, January, 1922.

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546

physical treatment is more fully recognised than inthis country, the number of cases of marked scoliosisis comparatively rare and severe cases still rarer.

It is impossible to judge as yet whether this is thetriumph and vindication of preventive treatment ornot, but the presumption is that we, in this country,lag behind. This is not due to lack of effort, but thediscussion showed that much of this effort is mis-directed. At the conclusion of the discussion it wasproposed, from the chair, that the Council of theSociety of Massage and Medical Gymnastics beapproached to form a committee to discuss the wholesubject with representative medical men. Thisconference will be charged to estimate what is goodand what is bad in our present management of thesecases ; what physical treatment can accomplish as acurative, palliative, or preventive agency; how

z’

much of the training of the medical gymnast is faulty,both from the view of excess and omission; andwhat can be done to secure better cooperation betweenmedical men and the gymnasts to whom they deputetheir treatment. It is to be hoped that represen-tatives of the Ling Association may also be invited tojoin in this conference, which, if successful, shouldprove of high value. _____

KING EDWARD VII. SANATORIUM, MIDHURST.THIS sanatorium was founded by H.M. King

Edward VII. in 1903, with funds provided by the lateSir Ernest Cassel, part of which were reserved forendowment. It was built expressly for educatedpersons of limited means who are suffering frompulmonary tuberculosis in an early stage. TheCouncil, we are informed, believe that there are manyindividuals in the above class who do not availthemselves of the benefits of the institution, becausetheir medical advisers are not aware of the uniqueadvantages which it presents ; and it is felt to bevery desirable to enlist the cooperation of such prac-titioners, whose knowledge of their patients will enablethem to select the person3 socially as well as physicallysuitable for admission. The advantages of site, environ-ment, building, and equipment of the sanatorium,which is placed in one of the loveliest parts of Sussex,are probably well known to our readers. The medicalattendance and nursing organisation is thorough andefficient for an establishment of 104 beds. It consistsof a medical superintendent, two assistant medicalofficers, a pathologist, and a visiting dental surgeon,while the institution is supervised by a consultingstaff of London physicians, who visit it with regularity.Our readers should also note that a report of thecondition of each patient on admission and on dischargeis sent to the medical man concerned in the case, whoalso receives the annual report of the work of theinstitution. The inclusive charge for maintenance andtreatment is at present 4t guineas weekly. Applica-tion for admission should be made to the MedicalSuperintendent, King Edward VII. Sanatorium, Mid-hurst, Sussex, who will forward all particulars.

THE WASSERMANN TEST IN GENERALPRACTICE.

To what extent are modern laboratory tests madeuse of in general practice ? Much depends on thescientific keenness of the practitioner. We imaginethat in almost every case of suspected phthisis a

specimen of sputum is subjected to a bacteriologicalexamination, either by the practitioner himself or insome laboratory. But with that exception it isquestionable if full use is made of laboratory facilities.The statistical returns made by public laboratoriesup and down the country do not, for instance, suggestthat the general practitioner sends many specimensto be examined either for the gonococcus or thespironema of syphilis. It may be, of course, that,with centralisation of treatment in the free venerealclinics, the general practitioner is seeing less and lessof these diseases, and therefore does not need labora-tory aid for their diagnosis. But he must comeacross many cases of obscure disease in which an

examination of the blood by the Wassermann testwould be of assistance in helping him to a diagnosis.While it cannot be too often emphasised that a positiveresult from the Wassermann test does not necessarilvmean that the immediate affection from which a,patient is suffering must be syphilitic-the result ofthe test must be weighed carefully along with all theclinical symptoms and the details of the patient’shistory-nevertheless the result of the Wassermanntest may be the determining factor in leading thepractitioner to a correct conclusion.

These remarks are suggested by an interestingarticle in the January number of the EdinburghMedical Journal by Dr. Arthur Mills, of Dundee, onthe Wassermann Test in General Practice. Dr. Millspoints out a fact that is daily becoming more and moreappreciated by all hospital surgeons-viz., that a

child may be suffering from hereditary syphiliswithout exhibiting any of the classical stigmata ofthat disease. He further shows that inheritedsyphilis may manifest itself in a variety of conditionswhich have not been hitherto recognised as dependingupon hereditary infection, but which yield rapidly toantiluetic treatment. From his experience in generalpractice, where he seems wisely to have lost no

opportunity of having the blood of his patientssubjected to the Wassermann test whenever he deemedit necessary, he has gathered a valuable collection ofsuggestive facts. His observations indicate that allfamily physicians would be well advised to make fre-quent use of the serological examination. Its resultmay prove as valuable an aid to them as it has tohim, and enable them to decide upon a correct line oftreatment in cases where, but for the laboratory test,the precise diagnosis would have been uncertain. Theperusal of Dr. Mills’s article will repay all practitioners,and be of profit to more than one specialist.

HOLES IN THE MACULA.’ THE condition known as " hole in the macula isone of the rarer results of a blow on the eye. Occasion-ally it is found in the course of disease ; F. A.Williamson-Noble,1 making a pathological examinationof an eye excised for absolute glaucoma secondary to-thrombosis of the central vein, has found this con-dition. A cyst had been formed at the macula betweenretina and choroid and the retinal layers overlying this.cyst had completely atrophied. The condition was,attributed to a toxic influence acting on the macularchoroidal capillaries and causing oedema. Then,according to Williamson-Noble, the fluid diffuses intothe potential space between the rods and cones andthe pigment epithelium, preventing the access ofnutrient materials from the chorio-capillaris, so thatthe superjacent retina degenerates and forms a hole.Can traumatic cases be similarly explained ? Accord-ing to Menteith Ogilvie, who made a collection of thesecases in 1900,2 the injury is the result of " contrecoup,’the waves of force initiated by the blow on the frontof the eye meeting at the posterior pole. Williamson-Noble suggests that the effect of this may be to-cause oedema, with cyst formation and the appear-ance of a hole just as in non-traumatic cases. Aunique case is reported from China by T. M. Li, ofPekin, 3 in which not one but both eyes were similarlyaffected. The patient was a soldier of 22 and receivedthe injury when playing football, being struck fairlyin the face by the ball and made unconscious for aboutten minutes. Typical holes in each macula were found,with poor vision and relative central scotomata. Thecondition subsequently improved. The ophthalmo-scopic picture of these cases is very striking and iswell represented in the papers already quoted byOgilvie and Li. Its distinguishing feature is a roundor oval area at the macula, cherry-red in colour, as.in cases of simple retinal oedema, but, unlike these,sharply defined and on a deeper level than the adjoiningfundus.

1 British Journal of Ophthalmology, February, 1922.2 Trans. Oph. Society, vol. xx.

3 American Journal of Ophthalmology, January, 1922.