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 Thought Induced Gene

Expression

Brishav RajbahakAbhishesh Bajracharya

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Contents

IntroductionProcess

Scope

ResutsRe!erences

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Introduction

Gene reguation "ethod that enabesthought-specifc brainwaves tocontro the conversion o! genes intoproteins

 Tap into hu"an brain#aves$ trans!erthe" #ireessy to a gene net#ork andreguate the expression

o! a genedependingon the type o!thought

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%u"an thoughts can be used to turn on

genes in "ice via genetically modifedcells (implants)

A tiny$ ight&based "achine uses peope'sbrain #aves to generate a (icker o! ight$

#hich then turns on genes in the brains o!"ice

Martin Fussenegger$ a pro!essor o!biotechnoogy and bioengineering$ and his

tea" at the Department o Biosystems(B-BSS)! "# $urich in S#it)eranddeveoped this gene reguation techni*ue

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+E, ight$ to be i"panted in "ice- Expresses gene in"odi.ed ces #hen s#itched on-

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Process

In their study$ /ussenegger and hiscoeagues asked severa vounteers tomeditate or concentrate 0by paying aga"e o! 12inecra!t34 or contro their brain

activity #ith bioeedbac% $ 0a techni*ue#here peope sync their brain #aves usinga guided dispay4

 The brain#aves thus produced #ere

recorded and anay)ed by an & headsetand !ed #ireessy via buetooth to acontroer that "anages a feld generator

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 This .ed generator created an

electromagnetic feld #hich gave thei"pant an induction current

 The induction current turns on an 'D

lamp in the i"pant #hich e"its near-inrared light

A ight&sensitive "odue reacts to near&in!rared ight #hich shines on a modifed

light-sensitive bacterial protein #ithin the i"pants

 This turns on a tailor-made gene snippet that encodes a speci.c hu"anprotein5 S 0Secreted Akaine

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Resuts

 Test subjects #ho payed 2inecra!t on theco"puter$ i-e- #ho #ere concentrating$induced average S values in theboodstrea" o! the "ice

Subjects #ho #ere co"petey reaxed0"editation4 recorded very high Svalues in the boodstrea" o! "ice

/or bio&!eedback$ the test subjects #ere

abe to consciousy s#itch the +E, ight onor o6 via the visua !eedback- This in turn#as re(ected by the varying amounts oS in the boodstrea" o! the "ice-

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 The optogenetic i"pant$ seen through the skin o! "ice-

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Scopes

Coud be used by peope #ho su6er!ro" chronic headaches or epilepsy to instanty deiver drugs !ro" a braini"pant #hen they experiencecharacteristic brain #aves at the onseto! pain or a sei)ure-

Coud eventuay be used in the hu"an

brain to deliver precise *uantitieso drugs as needed- Eg- Pain"anage"ent 7 reease o! endorphins

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,ra#backs

.nding reiabe signas o! inessin a !u))y "ass o! brain#aves

i"pants get covered #ith .brotic

scar tissue ha"pering the reeaseo! any proteins !ro" the i"pant

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Re!erence

http588###-sciencedaiy-co"8reeases89:;

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