thrombolytics have much broader indications than ... · aha/asa guideline 2015 american heart...

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ESC Heart & Brain Workshop Thrombolytics have much broader indications than mechanical thrombectomy in stroke Supported by Bayer, Bristol-Myers Squibb and Pfizer Alliance, Boehringer Ingelheim, Daiichi Sankyo Europe GmbH and Medtronic in the form of educational grants. The scientific programme has not been influenced in any way by its sponsors. Marta Rubiera, MD PhD Stroke Neurologist Hospital Vall d’Hebron

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Page 1: Thrombolytics have much broader indications than ... · AHA/ASA Guideline 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the

ESC Heart & Brain Workshop

Thrombolytics have much broader

indications than mechanical thrombectomy

in stroke

Supported by Bayer, Bristol-Myers Squibb and Pfizer Alliance, Boehringer Ingelheim, Daiichi Sankyo Europe GmbH and Medtronic in the form of educational grants. The scientific programme has not been influenced in any way by its sponsors.

Marta Rubiera, MD PhDStroke Neurologist

Hospital Vall d’Hebron

Page 2: Thrombolytics have much broader indications than ... · AHA/ASA Guideline 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the

Declaration of Interest

Nothing to declare

Page 3: Thrombolytics have much broader indications than ... · AHA/ASA Guideline 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the

Of course!!!

Page 4: Thrombolytics have much broader indications than ... · AHA/ASA Guideline 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the
Page 5: Thrombolytics have much broader indications than ... · AHA/ASA Guideline 2015 American Heart Association/American Stroke Association Focused Update of the 2013 Guidelines for the

Cardioembolic

Atherothrombotic

Lacunar

Infrequent

Cryptogenic

25-30 %

25 %

15-20%

5-10 %

20 %

Stroke subtypes

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Large vessel occlusion in acute stroke

PROACT : 43.8% M1-M2 occ

≈30-40%

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<6hours Code Stroke Catalunya 2016-2017

N 2778

Sex (male) 1436 (51,7%)

Age (mean +/- SD) 72,1 +/- 15,3

Pre-stroke mRS (median (IQR))

0 (0-2)

RACE (median (IQR)) 4 (2-6)

NIHSS (median (IQR)) 9 (4-18)

OTDT (mean +/- SD) 117 +/- 80

ASPECTS (median (IQR)) 10 (8-10)

Treatment (All, ischemic):EVTIVT

444 (16%, 25,2%)763 (27,5%, 43,3%)

M. Requena, MD. Poster presentation. ISC 2018

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Hypodensity >1/3 MCA territory

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ESO: ASPECTS <7 no tPA(<3h ??)

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alone

In conclusion…

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Stroke

Ischemic Stroke

Code Stroke

Reperfusioncandidates

IAReperfusioncandidates