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Treatment of Mitral Stenosis

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Page 1: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Treatment ofMitral Stenosis

Page 2: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Medical Valvotomy

Interventional Surgical

Treatment of Mitral Stenosis

Page 3: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Percutaneous MV Comissurotomy (PMC) Percutaneous MV Replacement ?

( new technique )

Interventional Valvotomy

Page 4: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Balloon commissurotomy Metallic commissurotomy

Percutaneous Mitral Valve Commissurotomy ( PMVC )

Page 5: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Antegrade ( Teansseptal ) Single balloon ( Inoue ) Double balloon

Retrograde ( Transatrial )

Balloon Commissurotomy

Page 6: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Most common procedure is Inoue balloon MVA become slightly more larger in double

balloon catheter than Inoue balloon Risk of perforation is greater in double

balloon procedure than Inoue balloon Suitable , when interatrial thrombosis is not

present

Antegrade PMVC

Page 7: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

When transseptal approach is contraindicated or impossible

Retrograde PMVC

Page 8: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Uses a device similar to the tubes dilator Efficacy similar to BMVC More demanding for operator than BMVC Advantage is that dilator is reusable

Metalic Commissurotomy

Page 9: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Symptomatic patients Asymptomatic patients

Indication of Valvotomy( most be individualized )

Page 10: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Sever MS ( MVA ≤ 1 cm2 ) Moderate MS ( MVA ≤ 1.5 cm2 )

Functional class II PA pressure > 60 mmHg Mean PCWP > 25 mmHg during exercise

Indication of Valvotomy in Symptomatic Patients , if:

Page 11: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Women with sever MS who wish to become pregnant

Who experience recurrent thromboembolie events

Who have sever pulmonary hypertension Atrial fibrillation ( persistent or recurrent )

Indication of Valvotomy in Asymptomatic Patients

Page 12: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Patients who indicated for valvotomy + good MV scoring (≤ 8 )

Indication of PMVC

Page 13: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Mobility ( 1-4 ) Subvalvular thickening ( 1-4 ) Leaflet thickening ( 1-4 ) Calcification ( 1-4 )

Mitral Valve Scoring

Page 14: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

LA thrombosis Floating in LA Attached to interatrial septum

Severe scoliosis IVC obstruction Major abnormalities of interatrial septum

Contraindication of PMVC

Page 15: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Percutaneous Local anesthesia Good hemodynamic result Good long-term outcome

Advantages of BMVC

Page 16: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

No direct visualization of valve Only feasible with flexible & non calcified

valves Contraindicated if MR> 2+ or LA clot is

present

Disadvantages of BMVC

Page 17: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Patient’s height Body surface area Diameter of Mitral annulus

Balloon Size

Page 18: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Cerebral emboli (1%) Cardiac Perforation (1%) Development of severe MR ( 2% need to

surgery ) Residual small ASD (5%)

Complication of PMVC

Page 19: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Valvotomy Closed MV commissurotomy ( CMVC) Open MV commissurotomy ( OMVC )

MV replacement Metallic Biologic

Surgical treatment of MS

Page 20: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Advantages : Off pump Inexpensive Relatively simple Good hemodynamic result Good long-term outcome

Closed MV commissurotoimy

Page 21: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Disadvantages : No direct visualization of valve Only feasible with flexible / non calcified valves Contraindicated if MR>2+ Need to general anesthesia

Closed MV commissurotoimy

Page 22: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Advantages : Risk of dislodging thrombi from the atrium or

calcium from valve s low Visualization of valve allows direct valvotomy Concurrent annuloplasty for MR is feasible

Open MV commissurotoimy

Page 23: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Disadvantages : Surgical procedure with general anesthesia Best results with flexible / non calcified valve

Open MV commissurotoimy

Page 24: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Combined MS + moderate to severe MR Extensive commissural calcification Severe fibrosis Subvalvular fusion Previous valvotomy Whose valves are not suitable for valvotomy :

MVA < 1.5 cm2 + Fc III-IV MVA < 1 cm2 + Fc II + PAP>70 mmHg

Indications of MVR

Page 25: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Bioprosthetic Mechanical :

Caged ball ( starr – Edwards) Tilting disc:

Monoleaflet ( Bjork – shiley ) Bioleaflet ( St. jude )

Prosthetic Mitral valve

Page 26: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

durability

Advantage of mechanical valve

Page 27: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Thromboembolism Valvular thrombus Valvular failure Valvular infection Pregnancy ( none of the 3 available anticoagulants have

been effective )

Disadvantage of mechanical valve

Page 28: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Double-crowned valved stent:1. Ventricular stent ( fixation of device to the

Mitral annulus )2. Atrial stent ( holds in place the homograft

sutured on the prosthesis ) The grocre between the two crowns is

placed at the level of the Mitral annulus Self-expandable artificial heart valve

Off pump MVR ( new technique)

Page 29: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Lt. posterolateral thoracotomy in 4th intercostal space

The atrium was punctured with a needle and a guide wire was inserted into it before a short 9-F sheath was introduced

Ivus was inserted in order to measure the diameter and Mitral valve area

Position of annulus was confirmed as well under the guidance of fluoroscopy

An incision of 1 cm was made on left atrium, centralled by the purse strings

Approach to off pump MVR

Page 30: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Mild peravalvular regurgitation due to mismatch between native annulus + valve size

LVOT obstruction due to protrusion of valved stents into the LV + push anterior of the MV towards the LVOT ( similar to SAM)

Complication of off pump MVR

Page 31: Treatment of Mitral Stenosis.  Medical  Valvotomy  Interventional  Surgical Treatment of Mitral Stenosis

Patients with : MR who no candidate for open heart surgery Severe CHF Hepatic failure Renal failure Restenosis of MV after PMC

Indication of off pump MVR