TRIGGERFISHGlaucoma Monitoring System

BME 181 Brittany M. Alphonse Biomedical Engineering

Table of Contents

Glaucoma Current Glaucoma

Monitoring Systems

Triggerfish Glaucoma Monitoring System

Triggerfish System Components

Benefits

Glaucoma

Progressive and Irreversible Disease leads to blindness

Deterioration of Optic Nerve fluid accumulates in eye high levels of liquid inside eye Diameter of cornea changes

Asymptomatic Contributor of disease:

frequent changes in pressure over the span of a day

high peaks in levels during night 4% of population is affected

40+ years of age

Current Glaucoma Monitoring Systems Measures static intraocular pressure Single Snapshots in Time

taken during the day when pressure is lowest

Monitoring in Overnight Sleep Labs cumbersome expensive

Frequent Punctual Measurements affects intraocular pressure checks pressure peaks

Triggerfish System

Created by SENSIMED First of its Kind on the

market constant reading

device Safety Approval in

Europe last year Expected U.S. Food

and Drug Administration Approval in late 2011

Non-Invasive Continuous Monitoring System

Measures Intraocular Pressure up to 24 hours

Does Not Interfere with Normal Vision

Constant Reading for Fraction of Price

Triggerfish System Components

Disposable Contact Lens soft hydrophilic silicone sensor and

microprocessor on outer edge

MEMS Sensor strain gauge monitors

diameter change in cornea

Telemetry Microprocessor Processes level changes transmits to receiver

Sensor and Processor

Components Continued

Circular Antenna taped around the eye

Sends Energy to Sensor

Receives Measurement Information

Connected to Portable Recorder thin flexible data cable

Antenna

Components Continued

Battery Powered Stores Measured

Information Wirelessly Uploads

Information Worn Around Neck

Ophthalmologist Receives Information

Visualize Intraocular Pressure Profile

Recorder/ Receiver Software

Benefits of Triggerfish System Improved Understanding of Pressure

Change pressure during day versus night

More Efficient Personalized Drug Delivery and Treatment Adapt Treatment

dependent on changing conditions Sensor is Placed Outside of Vision Field Early Diagnosis and Treatment

References for Pictures

http://www.sensimed.ch/S-Trig-benefits.htm

http://www.technologyreview.com/business/24931/page1/

http://www.sensimed.ch/S-Trig-solution.htm