In The Name of Allah Most Gracious Most Merciful

DEPARTMENT OF HEALTH AND MEDICAL SCIENCES

DEPARTMENT OF SCIENCES CENTRE FOR FOUNDATION STUDIES

INTERNATIONAL ISLAMIC UNIVERSITY MALAYSIA

BIOLOGY 1

HMM/ SCM1414 Tutorial 4 (CELL DIVISION)

Semester 1, 2007/2008

Answer all questions on these question papers.

Name : ……………………………………………………

Matric. No : ……………………………………………………

Programme : ……………………………………………………

Group no : ……………………………………………………

For Examiner’s Use

Section Question Marks

A Objective

B

C

Total Marks

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This question paper consists of 12 printed pages

SECTION A

Circle the correct answer

1 Diagram 1 shows a particular phase in an onion cell mitotic

division.

Diagram 1

Determine the phase shown in Diagram 1.

A Prophase B Metaphase C Anaphase D Telophase

2 In which phase of the cell cycle, are the chromosomes duplicated?

A S phase B G1 phase

C G2 phase D M phase

3 Cdk, MPF and cyclin are the cell products which involve in the regulation of cell cycle. Which of the following condition initiates

mitosis to start?

A Gradual increase in cyclin concentration

B Gradual increase in MPF concentration C Sudden decrease in MPF concentration

D Sudden decrease in Cdk concentration

4 In which phases are the checkpoints of the cell cycle control system?

I G1 II G2 III M IV S

A I and II B I, II and III

C I, II and IV D I, II, III and IV

5 Which of the following statements are true regarding the

chromosome structure?

I Composed of nucleosomes II Contains DNA and histone

III Consists of 150 million nucleotides IV Consists of two sister chromatids joint by centromere

A I and II B I, II and IV

C I, II and III D II, III and IV

6 Which is the longest phase of the cell cycle?

A Interphase B Mitosis

C Cytokinesis D G2 phase

7 Cytokinesis in plant cells occurs by the formation of

A cell wall B cell plate

C aster D spindle apparatus

8 If a cell of one organism has eight chromosomes, how many

chromosomes does the organism have in its gamete?

A Two B Four C Eight D Sixteen

9 In a plant cell, a centrosome functions in the formation of

A asters B centrioles

C kinetochores D spindle apparatus

10 Which of the following describe/s sister chromatids?

I Each has its own kinetochore

II They are formed during prophase III Moves to the opposite poles during telophase

IV Each has half the amount of the original chromosome’s genetic material

A I only B III only C III and IV D II, III and IV

SECTION B

Figure 1 shows the arrangement of two pairs of homologous

chromosomes in a particular stage during mitosis in a cell.

Figure 1

a) Name the mitotic stage shown in this figure. [1]

…………………………………………………………………………………………………….

b) i. Identify P. [1]

………………………………………………………………………………………….

ii. What is the role of P? [1]

…………………………………………………………………………………………..

iii. Name the protein subunits which make up P. [1]

…………………………………………………………………………………………..

P

c) In the box below, draw the chromosomes in a gamete produced by normal meiotic division of the chromosomes shown in

Figure 1. ( Assume that crossing over does not occur) [2]

d) In the box below, draw one of the pairs of homologous chromosomes as they would appear after crossing over has

occurred during meiosis. [2]

SECTION C

1 Describe the life cycle of one chromosome as it proceeds through the entire cell cycle. [15]

2 a) Describe the relative concentration of MPF, cyclins, and Cdks throughout the cell cycle. [10]

b) Define MPF and discuss briefly its role in the cell cycle. [5]

3 Do comparison between the chromosomal behaviour in meiosis

and mitosis. [15]

4 Compare and contrast the detailed meiotic stages in plant and animal cells. [15]