UCC1: New Course Transmittal FormDepartment Name and Number

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Prefix Level Course Number Lab Code

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Course Description (50 words or less)

Prerequisites Co-requisites

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Name

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Rev. 10/10

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Effective Term and Year Rotating Topic yes no

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yes no If yes, total repeatable credit allowed

Variable Credit yes no If yes, minimum and maximum credits per semester

Professional

Full Course Title

Microbiology and Cell Science

M C B 5 2 0 3Microbiology of Human Pathogens

MICRO HUMAN PATHOGENS

Fall 2013 ■

3 3 ■

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Survey of advanced topics and current scientific literature related to human host-pathogen interactionsand microbial pathogenesis, focusing on emerging bacterial and viral pathogens as agents of humandisease, biosecurity, molecular identification methods, spread of multi-drug resistance among bacterialpathogens, drug discovery and alternative treatment research.

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Currently our department does not offer a 3 credit, 5000 graduate level microbial pathogenesis course with a comprehensive "nuts and bolts" focus on mechanisms and emergingconcepts in virulence of bacterial and viral pathogenesis. This course is targeted towards 1st year MS students who have not previously taken an undergraduate pathogens course,and/or towards undergraduates wanting to take a graduate-level microbiology course. This course would be co-taught with our current MCB4203 (Bacterial and Viral Pathogens)course, with the graduate component requiring in-depth extra assigned readings and related testing, as well as the preparation of an online (recorded) lecture presentation in anassigned specific topic. Although this proposed cross-listed course may overlap in some course content with GMS6121 (Infectious Diseases; syllabus attached) that is offered bythe IDP program, course redundancy should not be a concern given the following key differences between GMS6121 and the MCB5203 proposed here. These differences include:(1) GMS6121 is a 6000-level, 4 credit course, while MCB5203 is a 3 credit, 5000 level course; (2) as a 6000-level, 4 credit course, GMS6121 is more comprehensive (in-depth),covering pathogenesis of bacteria, viruses, fungi, and parasites, while MCB5203 (3-credits) will focus on bacterial and viral pathogens only (3) GMS6121 primary target audience isPhD students, while MCB5203 primary target audience is undergraduate or MS students; (4) MCB5203 is structured so that it can be offered as an online course (with proctoredexams at distance sites) as well as an on-campus "hybrid" course. This flexibility will allow it to be an elective in the curriculum for a proposed online non-thesis MS degree that iscurrently in review for approval. Correspondence with the instructors of GMS6121 has confirmed that they do not envision overlap to be a problem (please see attachment).Because MCB4203 is already an approved undergraduate course in our department, a UCC1 form for MCB4203 was not included in this application.

kcrice@ufl.eduKelly C. Rice352-392-1192Elaine Turner(352) 392-1963

returner@ufl.edu

MCB 5203: MICROBIOLOGY OF HUMAN PATHOGENS Fall 2013 Period 1 (7:25 am – 8:15 am), M W F. Location: MCCC 0100 Instructor: Dr. Kelly Rice Office: Room 1147, Microbiology and Cell Science Bldg. Ph: 352-392-1192, email: kcrice@ufl.edu Office hours: Monday and Friday 10:00 am – 11:00 am Course Description: Survey of advanced topics and current scientific literature related to human host-pathogen interactions and microbial pathogenesis, focusing on emerging bacterial and viral pathogens as agents of human disease, biosecurity, molecular identification methods, spread of multi-drug resistance among bacterial pathogens, drug discovery and alternative treatment research.. Course Objectives: At the completion of this course, students should be able to: 1. Recognize the complex nature of microbial virulence, especially with respect to the multi-faceted interplay between the host immune system and pathogen 2. Describe (using specific examples) the strategies used by bacterial and viral pathogens that are required for host manifestation of disease (attachment and entry into host tissues, evasion of host immune defenses, multiplication in vivo, dissemination and transmission) 3. Identify strategies of treatment and prevention of host infection (ie. vaccines, antibiotics, antivirals, protective role of normal microbiota) and the ensuing response of the pathogen 4. Analyze hypothetical medical case studies using the knowledge gained from objectives 1-3 above. 5. Relate objectives 1-3 above to contemporary research literature in the field of microbial pathogenesis 6. Research, design and create a comprehensive recorded lecture outlining the history, pathogenesis, current treatment strategies, and unanswered questions of a historic, emerging or re-emerging pathogen. Required Textbooks: 1. Wilson et al. Principles of Bacterial Pathogenesis, A Molecular Approach (3rd Edition), ISBN 978-1-55581-418-2 2. Jawetz et al. Medical Microbiology, 25th Edition, ISBN 978-0-07-162496-1 Bibliography of Assigned Readings and Presentations (available online or through UF libraries): 1. Gibson, G. (2011), "Probiotics and prebiotics", in Finlay, B. (ed.), Microbiota: Agents for Health and Disease, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://hstalks.com/bio) 2. Thurlow, L. R., Joshi, G. S. and Richardson, A. R. (2012), Virulence strategies of the dominant USA300 lineage of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). FEMS Immunology & Medical Microbiology, 65: 5–22. doi: 10.1111/j.1574-695X.2012.00937.x 3. Daniel J. Hassett, Mark D. Sutton, Michael J. Schurr, Andrew B. Herr, Charles C. Caldwell, Joseph O. Matu. (2009), Pseudomonas aeruginosa hypoxic or anaerobic biofilm infections within cystic fibrosis airways, Trends in Microbiology, 17: 130-138, doi: 10.1016/j.tim.2008.12.003. 4. Rasko, D.A. and Sperandio. (2010). Anti-virulence strategies to combat bacteria-mediated disease. Nature Reviews in Drug Discovery. 9: 117-128. doi:10.1038/nrd3013.

5. Osterhaus, A.D. (2011), "Antivirals versus vaccines", in De Clercq, E. (ed.), Antivirals: Latest Developments and Future Progress, The Biomedical & Life Sciences Collection, Henry Stewart Talks Ltd, London (online at http://hstalks.com/bio) Overview of Course Format:

MCB5203 is co-taught with the undergraduate course MCB4203 (Bacterial and Viral Pathogens). In addition to the lecture material and exams that are shared with MCB4203, students enrolled in MCB5203 are required to complete the following: (1) 10% of each proctored exam I-IV will be drawn from a pool of questions specifically associated with an additional series of five assigned readings/presentations (see Bibliography above); (2) complete five hypothetical medical case study exercises; and (3) Research and prepare a recorded online lecture (see below for more details).

Course syllabus, lecture notes, and other tools will be available through the Sakai Learning Support System homepage [http://lss.at.ufl.edu/]. You will need to enter your Gatorlink username and password to access the system. If you do not have an active GatorLink ID, cannot remember your GatorLink login information, or if your ID does not work, please refer to the GatorLink website [http://gatorlink.ufl.edu] or to the UF Computing Help Desk (The Hub, 392-HELP) for assistance.

ATTENDANCE POLICY: All course lectures (3 per week) are recorded and posted on the Sakai course website, therefore attendance to in-class lectures is not mandatory. Weekly review sessions, special guest lectures, and proctored exams will always be held on Fridays during period 1 (MCCC 0100). Additional questions regarding lecture material should be addressed during weekly review sessions, during office hours, or in-person/by Skype by appointment. You are highly encouraged to participate in chat room discussions (via Sakai course website) that will be scheduled periodically throughout the semester (usually before each exam). The course instructor will not answer emails related to course content or study questions the night before a scheduled exam, so please make sure to take advantage of all the options mentioned above.

There will be five assigned readings and presentations to be completed throughout the semester (listed in the Bibliography above); online chat discussions moderated by the course instructor will be scheduled throughout the semester to review and discuss these assigned readings/presentations. Students are also highly encouraged to work together and discuss these readings (in person or online through Sakai chat room and/or discussion board). 10% of each proctored exam I-IV will be drawn from a pool of questions specifically associated with the content of these assigned readings/presentations.

There will be five “case-study” open-book quizzes (administered through Sakai) assigned throughout the semester, related to that specific week’s lecture material. Students are welcome to study together and in fact collaboration is encouraged on these case studies. However, each student is responsible for submitting his/her own quiz by the posted due date. Late submission or resubmission of case study quizzes will not be accepted!!

Each student enrolled in MCB5203 will be responsible for choosing a historic, emerging, or re-emerging pathogen (bacterial or viral) of interest, and researching and preparing a recorded online lecture (to be submitted through Sakai course website) outlining the history, pathogenesis (both host and pathogen aspects), current treatment strategies (if any), and unanswered questions in the field of study. A pool of 10 multiple-choice questions will also be submitted with each recorded lecture, and the instructor will choose questions from these pools that will

represent 15% of exam IV. This presentation will be due towards the end of the semester (to be announced), and students in enrolled in both MCB5203 and MCB4203 will be expected to watch these lectures prior to exam IV.

Overview of Proctored Exam Testing:

All proctored exams will be administered through Sakai and students will take them during period 1 on Fridays in MCCC 0100 (please refer to attached course schedule for specific dates and material to be covered in each exam). You MUST be present in the classroom to be able to take the exam.

Exams will begin promptly at 7:25 AM and end at 8:20 AM. Doors to the exam room will close at 7:45 AM and students will not be admitted after this time. Students may not leave and re-enter the room once the exam has started.

Each student is responsible for bringing a fully-charged and functional laptop computer (wireless internet and Sakai capable) with them to each scheduled exam. As there are an extremely limited number of electric outlets available in the classroom, it is the students’ responsibility to be prepared accordingly.

No materials (incl. cell phones, books, notes, etc.) except your laptop are allowed during the exam and should not be readily accessible.

When you have completed your exam (submitted through Sakai), you MUST IMMEDIATELY see a proctor to show them your picture ID (Gator1 card, driver’s liscense, passport, etc) and sign-out of the exam (printed first and last name, UFID #, and time of exit from the exam room) prior to exiting the room.

MAKE-UP EXAMS: If a student has a legitimate reason for missing an exam, the exam can be made-up at an alternative time as arranged with the course instructor. Documentation supporting the inability to write the exam at the scheduled time may be requested by the course instructor. Excused absences follow the criteria of the UF Graduate Catalogue (e.g., illness, serious family emergency, military obligations, religious holidays), and should be communicated to the instructor prior to the missed exam when possible.

GRADES - The grading scheme for this course is as follows:

EXAMS (4) - 150 points each (600 points total) Medical case studies (5) – 40 point each (200 points total) Recorded (online) oral presentation and multiple-choice question pool– 200 points TOTAL POINTS = 1000 Final letter grades will be assigned based on the number of points earned, as follows: A = 930-1000 points C+ = 770-799.9 points A- = 890 – 929.9 points C = 730-769.9 points B+ = 870 – 889.9 points C- = 700-729.9 points B = 840 – 869.9 points D+ = 650-699.9 points B- = 800-839.9 points D = 600-649.9 points E = 0-599.9 points For information on current UF policies for assigning grade points, see

https://catalog.ufl.edu/ugrad/current/regulations/info/grades.aspx Academic Honesty, Software Use, Campus Helping Resources, Services for Students with Disabilities Academic Honesty: In 1995 the UF student body enacted an honor code and voluntarily committed itself to the highest standards of honesty and integrity. When students enroll at the university, they commit themselves to the standard drafted and enacted by students. The Honor Pledge: We, the members of the University of Florida community, pledge to hold ourselves and our peers to the highest standards of honesty and integrity. On all work submitted for credit by students at the university, the following pledge is either required or implied: "On my honor, I have neither given nor received unauthorized aid in doing this assignment." Students should report any condition that facilitates dishonesty to the instructor, department chair, college dean, Student Honor Council, or Student Conduct and Conflict Resolution in the Dean of Students Office. (Source: 2012-2013 Undergraduate Catalog) It is assumed all work will be completed independently unless the assignment is defined as a group project, in writing by the instructor. This policy will be vigorously upheld at all times in this course. Software Use: All faculty, staff and students of the university are required and expected to obey the laws and legal agreements governing software use. Failure to do so can lead to monetary damages and/or criminal penalties for the individual violator. Because such violations are also against university policies and rules, disciplinary action will be taken as appropriate. Campus Helping Resources: Students experiencing crises or personal problems that interfere with their general well-being are encouraged to utilize the university’s counseling resources. The Counseling & Wellness Center provides confidential counseling services at no cost for currently enrolled students. Resources are available on campus for students having personal problems or lacking clear career or academic goals, which interfere with their academic performance. � University Counseling & Wellness Center, 3190 Radio Road, 352-392-1575, www.counseling.ufl.edu/cwc/ Counseling Services Groups and Workshops Outreach and Consultation Self-Help Library Training Programs Community Provider Database � Career Resource Center, First Floor JWRU, 392-1601, www.crc.ufl.edu/ Services for Students with Disabilities The Disability Resource Center coordinates the needed accommodations of students with disabilities. This includes registering disabilities, recommending academic accommodations within the classroom, accessing special adaptive computer equipment, providing interpretation services and mediating faculty-student disability related issues. 0001 Reid Hall, 352-392-8565, www.dso.ufl.edu/drc

SCHEDULE OF WEEKLY LECTURE TOPICS:

WK DATE TOPIC(S)

TEXTBOOK CHAPTERS

1 Introduction to Bacterial Pathogenesis, Koch’s Postulates

Wilson Chapters 1 & 6

2 First Lines of Host Defense (Skin and Mucosa, Normal Flora)

Wilson Chapters 2 & 5

3 Innate and Adaptive Host Immunity

Wilson Chapters 3-4

4 Pathogen Evolution, Measuring Infectivity and Virulence

Wilson Chapters 7-8

EXAM 1 FRIDAY _________

Lecture & Readings Weeks 1-4

5 Identification of Bacterial Virulence Factors (bacterial and host approaches)

Wilson Chapters 9-10

6 Bacterial Evasion of Host Defenses, Toxins, Virulence Regulation

Wilson Chapters 11-12

7 Antibiotic development, Emergence and Transmission of Resistance

Wilson Chapters 15,16

8 Vaccines, Non-antibiotic based treatment strategies

Wilson Chapter 17, TBA Assigned Readings

EXAM 2 FRIDAY________

Lecture & Readings Weeks 5-8

9 Introduction to Viruses, Pathogenesis and Control of Viral Diseases

Jawetz Chapters 29-30

10 Herpes, Pox, and Hepatitis Viruses Jawetz Chapters 33-35

11 Influenza, Vector-Borne Viruses, and MMR

Jawetz Chapters 38-40

EXAM 3 FRIDAY ______ Lecture & Readings Weeks 9-11

12 Human Cancer Viruses, HIV

Jawetz Chapters 43-44

13 Opportunistic Bacterial Infections

Wilson Chapters 18-19

14 Historic and Emerging Infectious Diseases

Graduate Student Presentations

15 Biosecurity, Diagnostic Medical Microbiology Wilson Chapter 20 and Jawetz Chapter 47

EXAM 4 Friday _____ Lecture & Readings Weeks 12-15

MCB 4203: BACTERIAL AND VIRAL PATHOGENS Fall 2013 Period 1 (7:25 am – 8:15 am), M W F. Location: MCCC 0100 Instructor: Dr. Kelly Rice Office: Room 1147, Microbiology and Cell Science Bldg. Ph: 352-392-1192, email: kcrice@ufl.edu Office hours: Monday and Friday 10:00 am – 11:00 am Course Description (from catalogue): Host-parasite relationships in the diseases of humans and animals, including the characteristics of bacterial and viral pathogens and the basic techniques of isolation and identification Course Objectives: At the completion of this course, students should be able to: 1. Recognize the complex nature of microbial virulence, especially with respect to the multi-faceted interplay between the host immune system and pathogen 2. Describe (using specific examples from select bacterial and viral pathogens) the strategies used by bacterial and viral pathogens that are required for host manifestation of disease (attachment and entry into host tissues, evasion of host immune defenses, multiplication in vivo, dissemination and transmission) 3. Identify strategies of treatment and prevention of host infection (ie. vaccines, antibiotics, antivirals, protective role of normal microbiota) and (where applicable) the ensuing response of the pathogen 4. Analyze hypothetical medical case studies using the knowledge gained from objectives 1-3 above. Required Textbooks: 1. Wilson et al. Principles of Bacterial Pathogenesis, A Molecular Approach (3rd Edition), ISBN 978-1-55581-418-2 2. Jawetz et al. Medical Microbiology, 25th Edition, ISBN 978-0-07-162496-1 Overview of Course Format:

This course is co-taught with MCB5203 (Microbiology of Human Pathogens). Course syllabus, lecture notes, and other tools will be available through the Sakai Learning

Support System homepage [http://lss.at.ufl.edu/]. You will need to enter your Gatorlink username and password to access the system. If you do not have an active GatorLink ID, cannot remember your GatorLink login information, or if your ID does not work, please refer to the GatorLink website [http://gatorlink.ufl.edu] or to the UF Computing Help Desk (The Hub, 392-HELP) for assistance.

ATTENDANCE POLICY: All course lectures (3 per week) are recorded and posted on the Sakai course website, therefore attendance to in-class lectures is not mandatory. Weekly review sessions, special guest lectures, and proctored exams will always be held on Fridays during period 1 (MCCC 0100). Additional questions regarding lecture material should be addressed during weekly review sessions, during office hours, or in-person/by Skype by appointment. You are highly encouraged to participate in chat room discussions (via Sakai course website) that will be scheduled periodically throughout the semester (usually before each exam). The course

instructor will not answer emails related to course content or study questions the night before a scheduled exam, so please make sure to take advantage of all the options mentioned above.

There will be four “case-study” open-book quizzes (administered through Sakai) assigned throughout the semester, related to that specific week’s lecture material. Students are welcome to study together and in fact collaboration is encouraged on these case studies. However, each student is responsible for submitting his/her own quiz by the posted due date. Late submission or resubmission of case study quizzes will not be accepted!!

Overview of Proctored Exam Testing:

All proctored exams will be administered through Sakai and students will take them during period 1 on Fridays in MCCC 0100 (please refer to attached course schedule for specific dates and material to be covered in each exam). You MUST be present in the classroom to be able to take the exam.

Exams will begin promptly at 7:25 AM and end at 8:20 AM. Doors to the exam room will close at 7:45 AM and students will not be admitted after this time. Students may not leave and re-enter the room once the exam has started.

Each student is responsible for bringing a fully-charged and functional laptop computer (wireless internet and Sakai capable) with them to each scheduled exam. As there are an extremely limited number of electric outlets available in the classroom, it is the students’ responsibility to be prepared accordingly.

No materials (incl. cell phones, books, notes, etc.) except your laptop are allowed during the exam and should not be readily accessible.

When you have completed your exam (submitted through Sakai), you MUST IMMEDIATELY see a proctor to show them your picture ID (Gator1 card, driver’s liscense, passport, etc) and sign-out of the exam (printed first and last name, UFID #, and time of exit from the exam room) prior to exiting the room.

MAKE-UP EXAMS: If a student has a legitimate reason for missing an exam, the exam can be made-up at an alternative time as arranged with the course instructor. Documentation supporting the inability to write the exam at the scheduled time may be requested by the course instructor. Excused absences follow the criteria of the UF Undergraduate Catalogue (e.g., illness, serious family emergency, military obligations, religious holidays), and should be communicated to the instructor prior to the missed exam when possible.

GRADES - The grading scheme for this course is as follows:

Case-study “open-book” quizzes (4) - 50 points each (200 points total) EXAMS (4) - 200 points each (800 points total) TOTAL POINTS = 1000 Final letter grades will be assigned based on the number of points earned, as follows: A = 930-1000 points C+ = 770-799.9 points A- = 890 – 929.9 points C = 730-769.9 points B+ = 870 – 889.9 points C- = 700-729.9 points B = 840 – 869.9 points D+ = 650-699.9 points

B- = 800-839.9 points D = 600-649.9 points E = 0-599.9 points For information on current UF policies for assigning grade points, see https://catalog.ufl.edu/ugrad/current/regulations/info/grades.aspx Academic Honesty, Software Use, Campus Helping Resources, Services for Students with Disabilities Academic Honesty: In 1995 the UF student body enacted an honor code and voluntarily committed itself to the highest standards of honesty and integrity. When students enroll at the university, they commit themselves to the standard drafted and enacted by students. The Honor Pledge: We, the members of the University of Florida community, pledge to hold ourselves and our peers to the highest standards of honesty and integrity. On all work submitted for credit by students at the university, the following pledge is either required or implied: "On my honor, I have neither given nor received unauthorized aid in doing this assignment." Students should report any condition that facilitates dishonesty to the instructor, department chair, college dean, Student Honor Council, or Student Conduct and Conflict Resolution in the Dean of Students Office. (Source: 2012-2013 Undergraduate Catalog) It is assumed all work will be completed independently unless the assignment is defined as a group project, in writing by the instructor. This policy will be vigorously upheld at all times in this course. Software Use: All faculty, staff and students of the university are required and expected to obey the laws and legal agreements governing software use. Failure to do so can lead to monetary damages and/or criminal penalties for the individual violator. Because such violations are also against university policies and rules, disciplinary action will be taken as appropriate. Campus Helping Resources: Students experiencing crises or personal problems that interfere with their general well-being are encouraged to utilize the university’s counseling resources. The Counseling & Wellness Center provides confidential counseling services at no cost for currently enrolled students. Resources are available on campus for students having personal problems or lacking clear career or academic goals, which interfere with their academic performance. � University Counseling & Wellness Center, 3190 Radio Road, 352-392-1575, www.counseling.ufl.edu/cwc/ Counseling Services Groups and Workshops Outreach and Consultation Self-Help Library Training Programs Community Provider Database � Career Resource Center, First Floor JWRU, 392-1601, www.crc.ufl.edu/ Services for Students with Disabilities

The Disability Resource Center coordinates the needed accommodations of students with disabilities. This includes registering disabilities, recommending academic accommodations within the classroom, accessing special adaptive computer equipment, providing interpretation services and mediating faculty-student disability related issues. 0001 Reid Hall, 352-392-8565, www.dso.ufl.edu/drc

SCHEDULE OF WEEKLY LECTURE TOPICS:

WK DATE TOPIC(S)

TEXTBOOK CHAPTERS

1 Introduction to Bacterial Pathogenesis, Koch’s Postulates

Wilson Chapters 1 & 6

2 First Lines of Host Defense (Skin and Mucosa, Normal Flora)

Wilson Chapters 2 & 5

3 Innate and Adaptive Host Immunity Wilson Chapters 3-4

4 Pathogen Evolution, Measuring Infectivity and Virulence

Wilson Chapters 7-8

EXAM 1 FRIDAY _________

Lecture & Readings Weeks 1-4

5 Identification of Bacterial Virulence Factors (bacterial and host approaches)

Wilson Chapters 9-10

6 Bacterial Evasion of Host Defenses, Toxins

Wilson Chapters 11-12

7 Antibiotic development, Emergence and Transmission of Resistance

Wilson Chapters 15,16

8 Vaccines, Non-antibiotic based treatment strategies

Wilson Chapter 17, TBA Assigned Readings

EXAM 2 FRIDAY________

Lecture & Readings Weeks 5-8

9 Introduction to Viruses, Pathogenesis and Control of Viral Diseases

Jawetz Chapters 29-30

10 Herpes, Pox, and Hepatitis Viruses Jawetz Chapters 33-35

11 Influenza, Vector-Borne Viruses, and MMR

Jawetz Chapters 38-40

EXAM 3 FRIDAY ______ Lecture & Readings Weeks 9-11

12 Human Cancer Viruses, HIV

Jawetz Chapters 43-44

13 Opportunistic Bacterial Infections

Wilson Chapters 18 and 19

14 Historic and Emerging Infectious Diseases

MCB5203 Graduate Student Presentations

15 Biosecurity, Diagnostic Medical Microbiology Wilson Chapter 20 and Jawetz Chapter 47

EXAM 4 Friday _____ Lecture & Readings Weeks 12-

15

UCC: Syllabus Checklist

Rev. 10/10

All UCC1 forms and each UCC2 form that proposes a change in the course description or credit hours must include this checklist in addition to a complete syllabus. Check the box if the attached syllabus includes the indicated information.

Instructor contact information (and TA if applicable)

Course objectives and/or goals

Policy related to class attendance

Policy related to make-up exams or other work

Statement related to accommodations for students with disabilities

Information on current UF grading policies for assigning grade points

Syllabus MUST contain the following information:

It is recommended that syllabi contain the following information:

1. Critical dates for exams and other work

2. Class demeanor expected by the professor (e.g., tardiness, cell phone usage)

4. Contact information for university counseling and mental health services

The University’s complete Syllabus Policy can be found at:

3. UF’s honesty policy

http://www.aa.ufl.edu/policy/SyllabiPolicy.pdf

A topical outline (at least tentative) of subjects to be covered

Required and recommended textbooks

Methods by which students will be evaluated and their grades determined

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Re: question about GMS6121

https://mail.ufl.edu/...KQAAAADmffAADFo4UtxxSDTLJi8nOhIz7gAABYMempAAAJ&a=Print&pspid=_1357331777697_596136364[1/4/2013 3:37:04 PM]

Re: question about GMS6121Giron,Jorge ASent:Friday, January 04, 2013 3:24 PMTo: Grieshaber,ScottCc: Rice,Kelly C; Grieshaber,Scott; Giron,Jorge A

Hi KellyI agree with Scott. Let us know if we can be of help.ThanksJorge

Sent from my iPhone

On Jan 4, 2013, at 1:50 PM, "Grieshaber,Scott" <SGRIESHABER@dental.ufl.edu> wrote:

Hi Kelly,

Although the outline and content follow similar outlines I think the niche the two courses fill aredistinct. The primary focus for Jorge and My course is for the Immuno-micro concentration IDPstudents and there are no current plans to expand it to fill a larger niche. So as far as I amconcerned there is no real overlap. If I can be of any help in any way let me know.

Scott

Scott Grieshaber Ph.D.Assistant ProfessorUniversity of FloridaDepartment of Oral BiologySchool of DentistryPO BOX 100424 Room DG-561600 SW Archer RoadGainesville FL 32610(352) 273-8856sgriesha@ufl.edu

On Jan 4, 2013, at 1:28 PM, "Rice,Kelly C" <kcrice@ufl.edu> wrote:

Hi Drs. Giron and Grieshaber, I have been working on developing a cross-listed 5000-level version of our department's MCB4203"Bacterial and Viral Pathogens" course (proposed syllabus is attached). The primary target audience forthis potential 5000-level course (MCB5203) would be undergraduates wishing to take a graduate levelcourse (as an elective) and/or first year non-thesis MS students. It would be a 3-credit course thatwould be offered either as a "hybrid" (online/in-person lecture) course on-campus or as an online coursefor distance students. Although the two courses seem to be distinct in terms of target students, coursedelivery method, and course content/scope (MCB5203 only focuses on bacterial and viral pathogens), Iwas hoping to get your feedback on this and whether you think there is concern for potential overlapbetween MCB5203 and GMS6121? If you could let me know your thoughts on this in the next few daysthat would be great. If overlap is a concern, perhaps we could meet in the near future to discuss in moredetail. Thanks and I look forward to hearing from you, Kelly Kelly C. Rice, PhD.

Re: question about GMS6121

https://mail.ufl.edu/...KQAAAADmffAADFo4UtxxSDTLJi8nOhIz7gAABYMempAAAJ&a=Print&pspid=_1357331777697_596136364[1/4/2013 3:37:04 PM]

Assistant ProfessorDept. of Microbiology and Cell Science, IFASUniversity of FloridaRm. 1147, Bldg. 981 Museum Rd.PO BOX 110700Gainesville, FL 32611-0700352-392-1192 (office)352-392-7797 (lab)kcrice@ufl.edu<MCB 5203 syllabus.pdf>

GMS 6121 – Infectious Diseases (4 credits)

SPRING 2012 Lectures Mon/Wed/Fri 9:35-10:25 in ARB Room R2-265 Discussions Thursdays 9:35 – 11:30 am in ARB R2-133

Director: Jorge A Girón, Ph.D. Co-Director: Scott Grieshaber, Ph. D. Phone: 273 8892; email: jagiron@ufl.edu Phone:846 0265; email: grieshaber@dental.ufl.edu Office: EPI Building Rm 472 Office: Department of Oral Biology Course Overview The goal of this course is to enable students with microbiology and molecular genetics background to further their understanding of the principles and mechanisms of microbial pathogenesis. Main molecular and cellular aspects of pathogenicity and host cell interaction of medically most important bacterial pathogens, viruses, fungi, and parasites will be reviewed. This 4-credit graduate level course is required as a core course for PhD students in the Immunology & Microbiology concentration of the biomedical sciences PhD program and is taught concurrently with the course GMS 6140, Principles of Immunology. Students in other UF graduate programs are welcome to take the course with consent of the course directors. The instructors are trained molecular microbiologists with particular interests in pathogenesis and their labs employ molecular genetics principles and techniques in their research.

Lectures will take place Mondays, Wednesdays and Fridays from 9:35 to 10:25 am in room ARB R-2-265 and the discussions of Special Topics in Infectious Diseases will run Thursdays 9:25-11:30, in room ARB R2-133. In these latter 2-hour-sessions, the students will present and discuss research articles previously selected by the instructors. Attendance and participation of the students in the discussion of papers is required and will be evaluated by the instructors.

Prerequisites General Microbiology, Biochemistry, and Cell Biology

Evaluation Students will take 4 exams and the grade will be 80% of the final grade. The remaining 20% will come from the evaluations of the discussion sessions. General Course Materials are available in the ModuleCore using your Gatorlink username and password Bibliography - Bacterial Pathogenesis – A Molecular Approach. 2nd Ed. A.A. Salyers & D. D. Whitt. ASM Press. - Schaechter’s Mechanisms of Microbial Diseases. 4th Ed. Edited by NC Englebert, V. Dirita, and TS Dermody. Publisher Lippincott William & Wilkins. - Cellular Microbiology. Eds. P. Cossart, P. Boquet, S. Normark, & R. Rappuoli. 2nd . Ed. ASM Press. Other suggested reading assignments are or will be posted in the moduleCore.