what is nescent? inspired by the national center for ecological analysis and synthesis what is...
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What is NESCent?
Inspired by the National Center forEcological Analysis and Synthesis
What is NESCent?
Downtown Durham, North Carolina
National Evolutionary Synthesis Center
Consortium of 3 Research Triangle Universities
Director
Kathleen Smith DUKE
Associate Directors
Cliff Cunningham DUKE Research and Development
Greg Gibson NC State Education and Outreach
Joel Kingsolver UNC Science and Synthesis
Todd Vision UNC Science and Synthesis
The In-House Community
• 15 Post-Doctoral Fellows
• 5 Sabbatical Faculty
• 3 Triangle Faculty (on teaching leaves)
• Synthesis Working Groups (NCEAS-Style)
• 12 people, meet several times
• Assumption … the data is out there!
Meetings to Catalyze and Achieve Synthesis
• “Catalysis Meetings” 30 people around a central theme
• Lead to Grand Scale Research Collaborations
Meetings to Catalyze and Achieve Synthesis
What is Synthesis?
Who is Occupying Real Estate in the Informatics Universe
(and doing it well)
Jump-StartingEvolutionary Databases
Find “homes” for all data associated with submitted evolutionary papers
Gen
otyp
e Phenotype
Vertical Integration(lots of data on single species)
Horizontal Integration(smaller amounts of data for many individuals and species)
GenomicSequences
GenomicMaps
QuantitativeTrait loci
Gene Expression:Microarrays
Gene Expression:
In-situ Images
Mutation Phenotypes2D Images
Sequences FromMany
Individuals
Specimen Collection Data, GIS
Phylogenetic Relationships
QuantitativeMorphometric
Behavioral
Matrix-CodedMorphological
Behavioral
Specimen and Character
Images
GENBANK
Generic Model Systems
(GMOD)Assembling Tree of
LifeMorphBank
MorphoBankDigi-MorphTreeBase
(GBIF)
BarCode of Life DataBase (BOLD)
Population Genetic
Database
PEET Taxonomic Databases
CHRONOS
PaleoBiology Database Taxonomic Name
Databases
VegBank
FlyBase, TAIR
Find “homes” for all data associated with submitted evolutionary papers
Jump-StartingEvolutionary Databases
Each with Unique Challenges Inhibiting Data Population
Foster “Nascent” DataBases(Controlled Ontologies)
MorphBank/MorphBank
Proliferation/Confusion
MorphBank/MorphoBank Summit:Neutral Site, LSID’s, Inter-operability
Foster “Nascent” DataBases(Controlled Ontologies)
MorphBank/MorphBank
Proliferation/Confusion
Each with Unique Challenges Inhibiting Data Population
Foster “Nascent” DataBases(Controlled Ontologies)
PopulationGenetic
DataBase
CoordinatingData Submission
Data Submission Tools for Multiple Databases
Foster “Nascent” DataBases(Controlled Ontologies)
PopulationGenetic
DataBase
CoordinatingData Submission
Each with Unique Challenges Inhibiting Data Population
Foster “Nascent” DataBases(Controlled Ontologies)
Etho-Source
Ontology-WrittenNeed Programmer!
Wouldn’t it be great if all communities did this?
Foster “Nascent” DataBases(Controlled Ontologies)
Etho-Source
Ontology-WrittenNeed Programmer!
Find “homes” for all data associated with
submitted evolutionary papers
Establish an evolutionary data registry(building on the ecological data registry)
Jump-StartingEvolutionary Databases
Data Centers
Meta-Data Registry
LSID’s to follow data to final “home”
Wall of China Model-1
Facilitate Evolutionary Model Systems
(GMOD)
INTEGRATE TAXONOMIC AND
MODEL SYSTEMS ONTOLOGIES!
Wall of China Model-2
Targeted Sabbaticals and Working Groups
INTEGRATE TAXONOMIC AND
MODEL SYSTEMS ONTOLOGIES!
Wall of China Model-2
Quentin CronkTodd VisionLincoln Stein
Paula MabeeCTOL-Z-Fin
Software Integration
W. Maddison An “Economy” of Service Oriented Providers
Gen
otyp
e Phenotype
Vertical Integration(lots of data on single species)
Horizontal Integration(smaller amounts of data for many individuals and species)
GenomicSequences
GenomicMaps
QuantitativeTrait loci
Gene Expression:Microarrays
Gene Expression:
In-situ Images
Mutation Phenotypes2D Images
Sequences FromMany
Individuals
Specimen Collection Data, GIS
Phylogenetic Relationships
QuantitativeMorphometric
Behavioral
Matrix-CodedMorphological
Behavioral
Specimen and Character
Images
GENBANK
Generic Model Systems
(GMOD)Assembling Tree of
LifeMorphBank
MorphoBankDigi-MorphTreeBase
(GBIF)
BarCode of Life DataBase (BOLD)
Population Genetic
Database
PEET Taxonomic Databases
CHRONOS
PaleoBiology Database Taxonomic Name
Databases
VegBank
FlyBase, TAIR