6. animal tissues
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Tissues are groups of specialized cells that work together for a
particular function.
There are four types of tissue.
Epithelial(covering) Connective (support)
Muscle(movement)
Nervous(control)
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Epithelial tissues cover body surfaces.
Outer layer of skin and the lining of organs
Also found in glandular tissue
Play roles in absorption, filtration, secretion, and protection
against foreign substances
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Usually fit closely together in continuoussheets
Exception: glandular epithelium
Avascular(Have no blood supply of theirown)
How do they get nutrients?
If well nourished, epithelial cells
regeneratethemselves easily.
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Have one free (unattached) surface or
edge called the apical surface
Exposed to bodys exterior or to the
cavity of an internal organ
Lower surface of an epithelium rests
on a basement membrane
Structureless material secreted by
both the epithelial cells and the
connective tissue cells
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Each epithelium is given 2 names
First: indicates relative number of
CELL LAYERS
Simple(one layer of cells)
Stratified(more than one cell
layer)
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Second: describes the SHAPE OFCELLS
Squamous(cells flattened likescales)
Cuboidal(cube-shaped)
Columnar(shaped like columns)
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Simple squamous (SS) tissue is composed of flat, scale-like cellsthat usually forms membranes
It lines the walls of blood vessels, pulmonary alveoli (ss), and thelining of the heart, lung, and peritoneal cavities.
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This tissue is composed of a single layer of cube-like cells. It lines the walls of kidney tubules, covers the surface of ovaries,and is common in glands and their ducts.
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This tissue is composed of a single layer of tall cells. It often includes mucus-producing goblet cells.
It often lines the digestive tract.
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Although this tissue appears stratified,it is actually composed of a single layerof cells of different types.
Although their nuclei are found at
different levels, each cell adjoins thebasal membrane (BM).
This tissue lines the larger respiratorypassageways.
It is often ciliated (arrows).
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Main functions: absorption and secretion Ciliated variety lines respiratory tract
Mucus produced by goblet cellstrapsdust and other debris
Cilia propel mucus upward and away from the lungs
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The term stratifiedrefers to the layered arrangement of cells.
The outer layers of cells appear flat, but the inner cells vary in shapefrom cuboidal to columnar.
Stratified squamous epithelium serves as a barrier to the outsideenvironment in locations such as the skin, mouth, and esophagus.
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Stratified cuboidal epithelium (SC) is found in the ducts of sweatglands and surrounds Graafian follicles of ovaries(shown below).
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Shape of cells depends upon the amount of stretching It lines organs of the urinary system.
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Some epithelial membranes are
made up of cells with cilia, tiny
projections that beat in unison to
move mucus along the surface.
Ciliated epithelia in the trachea,
for example, sweep debris out of
the respiratory tract.
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A gland is defined as one or more cells responsible for secreting aparticular product
Two major gland types
Exocrine gland
Secretions empty through ducts to the epithelial surface
Include sweat and oil glands
Endocrine gland
Ductless since secretions diffuse into blood vessels
All secretions are hormones
Examples include pituitary, pancreas, ovaries, testes
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Connective tissue differs from other tissues in that it contains large
amounts of extracellular matrix.
Extracellular matrix is nonliving material that surrounds living cellsIt is found everywhere and includes the most abundant and widely
distributed tissue
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Connective tissues function to
bind other tissues together
provide support
provide nourishment
store wastes repair damaged tissues
These tissues are generally well vascularized
Exceptions: tendons, ligaments, cartilage The exceptions are avascular
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Two main elements:
Ground substance
Mostly water along with
glycoproteins and large
polysaccharide molecules
May be liquid, gel-like, or rock-hard
Fibers
Collagen fibers (high strength)
Elastic fibers (stretch and recoil) Reticular fibers (fine fibers, internal
skeleton)
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Bone
Various types of cartilage
Adipose tissue Dense and loose connective tissue
Blood
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Composed of
Bone cells in lacunae (cavities)
Hard matrix of calcium salts
Large numbers of collagen fibers
Used to protect and support the body
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Most common type of cartilage
Composed ofcollagen fibers hidden by a rubbery matrix with a
glassy blue-white appearance
Found in the larynx, attaches ribs to sternum, at the end of
many bones
Entire fetal skeleton before birth
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Elastic
Provides elasticity
Supports the external ear
Fibrocartilage
Highly compressible Forms cushion-like discs between
vertebrate
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Dense connective tissue contains a large number of fibers with
only a few cells. Fibers shown here are all running parallel to each other, and no
cells are present.
Tendons (muscle to bone) and ligaments (bone to bone) arecomposed of dense connective tissue.
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Loose connective tissue has few fibers, a number of cell types,
and a large amount of matrix. It functions to bind epithelia to underlying tissues.
Includes areolar, adipose, & reticular connective
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Most widely distributed connectivetissue
Soft, pliable cobwebby tissue thatcushions and protects the bodys
organs it wraps
Holds internal organs together and intheir proper positions
Under microscope: matrix appears asempty space, reservoir of water andsalts
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When a body region is inflamed, the areolar tissue in the area soaks
up the excess fluid like a sponge, and the area swells andbecomes puffy.
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Adipose cells are bundled together by connective tissue.
Each cell appears as a clear space, representing the site of thelarge drop of lipid (fat) before it dissolved during preparation ofthe microscope slide.
The nuclei appear as small disks on the periphery of cells.
Functions to insulate the body, protect organs, and fuel storage
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Consists of a delicate network of interwoven reticular fibers Forms the stroma(internal framework) which can support free blood
cells in lymphoid organs (lymph nodes, spleen, & bone marrow)
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Consists of blood cells surrounded by nonliving, fluid matrix
called blood plasma Fibersonly visible during blood clotting
Functions as a transport medium for materials
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Muscle is a contractile tissue.
There are three types of muscle:
Skeletal
Cardiac Smooth
Main function is to produce movement.
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Under voluntarycontrol
Contracts to pull on bones or skin Produces gross body movements or facial expressions
Characteristics of skeletal muscle cells
Striated (stripe-like pattern)
Multinucleate (more than one nucleus)
Long, cylindrical
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Under involuntarycontrol
Found only in the heart Function is to pump blood
Characteristics of cardiac muscle cells
Cells are attached to other cardiac muscle cells at
intercalateddisks
Striated
One nucleus/cell
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Under involuntarymuscle
Found in walls of hollow organs such as stomach, uterus, andblood vessels
Characteristics of smooth muscle cells
No visible striations
One nucleus/cell Spindle-shaped cells
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Nervous tissue, which occurs throughout the body, receives and
transmits stimuli. It converts a stimulus, whether chemical or physical in nature,
into an electrical impulse that is conducted by neurons.
Nervous tissue also consists of glia, which are the various types
of supporting cells in the nervous system.
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The surface of the cerebellum is
highly fissured. Outer layer is the molecular layer,
which contains some glial cells but
consists mostly of neuronal processes
(dendrites and axons).
Darkly stained area is the granularlayer and is composed mostly of
nerve cell bodies of tiny granule cells
(a neuron type) along with some
larger Golgi cells (another neuron
type). Between the molecular and granular
layers lies the Purkinje layer.
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Immunohistochemistry is used to reveal BrdU (brown), athymidine analog that is incorporated in cells undergoing S phase. Cellsstained brown were caught in the act of DNA synthesis. These cells arefound in the hippocampus, one of the only brain regions where newneurons are formed.
(One example)
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Immunofluorescence labeling shows new neurons in the hippocampus.
Green is BrdU (the marker that labels cells undergoing S phase), red is a
NeuN (a neuron-specific marker), and blue is GFAP (a glial marker). Cells
co-labeled green and red are new neurons.
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