6. animal tissues

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    Tissues are groups of specialized cells that work together for a

    particular function.

    There are four types of tissue.

    Epithelial(covering) Connective (support)

    Muscle(movement)

    Nervous(control)

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    Epithelial tissues cover body surfaces.

    Outer layer of skin and the lining of organs

    Also found in glandular tissue

    Play roles in absorption, filtration, secretion, and protection

    against foreign substances

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    Usually fit closely together in continuoussheets

    Exception: glandular epithelium

    Avascular(Have no blood supply of theirown)

    How do they get nutrients?

    If well nourished, epithelial cells

    regeneratethemselves easily.

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    Have one free (unattached) surface or

    edge called the apical surface

    Exposed to bodys exterior or to the

    cavity of an internal organ

    Lower surface of an epithelium rests

    on a basement membrane

    Structureless material secreted by

    both the epithelial cells and the

    connective tissue cells

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    Each epithelium is given 2 names

    First: indicates relative number of

    CELL LAYERS

    Simple(one layer of cells)

    Stratified(more than one cell

    layer)

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    Second: describes the SHAPE OFCELLS

    Squamous(cells flattened likescales)

    Cuboidal(cube-shaped)

    Columnar(shaped like columns)

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    Simple squamous (SS) tissue is composed of flat, scale-like cellsthat usually forms membranes

    It lines the walls of blood vessels, pulmonary alveoli (ss), and thelining of the heart, lung, and peritoneal cavities.

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    This tissue is composed of a single layer of cube-like cells. It lines the walls of kidney tubules, covers the surface of ovaries,and is common in glands and their ducts.

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    This tissue is composed of a single layer of tall cells. It often includes mucus-producing goblet cells.

    It often lines the digestive tract.

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    Although this tissue appears stratified,it is actually composed of a single layerof cells of different types.

    Although their nuclei are found at

    different levels, each cell adjoins thebasal membrane (BM).

    This tissue lines the larger respiratorypassageways.

    It is often ciliated (arrows).

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    Main functions: absorption and secretion Ciliated variety lines respiratory tract

    Mucus produced by goblet cellstrapsdust and other debris

    Cilia propel mucus upward and away from the lungs

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    The term stratifiedrefers to the layered arrangement of cells.

    The outer layers of cells appear flat, but the inner cells vary in shapefrom cuboidal to columnar.

    Stratified squamous epithelium serves as a barrier to the outsideenvironment in locations such as the skin, mouth, and esophagus.

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    Stratified cuboidal epithelium (SC) is found in the ducts of sweatglands and surrounds Graafian follicles of ovaries(shown below).

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    Shape of cells depends upon the amount of stretching It lines organs of the urinary system.

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    Some epithelial membranes are

    made up of cells with cilia, tiny

    projections that beat in unison to

    move mucus along the surface.

    Ciliated epithelia in the trachea,

    for example, sweep debris out of

    the respiratory tract.

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    A gland is defined as one or more cells responsible for secreting aparticular product

    Two major gland types

    Exocrine gland

    Secretions empty through ducts to the epithelial surface

    Include sweat and oil glands

    Endocrine gland

    Ductless since secretions diffuse into blood vessels

    All secretions are hormones

    Examples include pituitary, pancreas, ovaries, testes

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    Connective tissue differs from other tissues in that it contains large

    amounts of extracellular matrix.

    Extracellular matrix is nonliving material that surrounds living cellsIt is found everywhere and includes the most abundant and widely

    distributed tissue

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    Connective tissues function to

    bind other tissues together

    provide support

    provide nourishment

    store wastes repair damaged tissues

    These tissues are generally well vascularized

    Exceptions: tendons, ligaments, cartilage The exceptions are avascular

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    Two main elements:

    Ground substance

    Mostly water along with

    glycoproteins and large

    polysaccharide molecules

    May be liquid, gel-like, or rock-hard

    Fibers

    Collagen fibers (high strength)

    Elastic fibers (stretch and recoil) Reticular fibers (fine fibers, internal

    skeleton)

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    Bone

    Various types of cartilage

    Adipose tissue Dense and loose connective tissue

    Blood

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    Composed of

    Bone cells in lacunae (cavities)

    Hard matrix of calcium salts

    Large numbers of collagen fibers

    Used to protect and support the body

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    Most common type of cartilage

    Composed ofcollagen fibers hidden by a rubbery matrix with a

    glassy blue-white appearance

    Found in the larynx, attaches ribs to sternum, at the end of

    many bones

    Entire fetal skeleton before birth

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    Elastic

    Provides elasticity

    Supports the external ear

    Fibrocartilage

    Highly compressible Forms cushion-like discs between

    vertebrate

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    Dense connective tissue contains a large number of fibers with

    only a few cells. Fibers shown here are all running parallel to each other, and no

    cells are present.

    Tendons (muscle to bone) and ligaments (bone to bone) arecomposed of dense connective tissue.

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    Loose connective tissue has few fibers, a number of cell types,

    and a large amount of matrix. It functions to bind epithelia to underlying tissues.

    Includes areolar, adipose, & reticular connective

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    Most widely distributed connectivetissue

    Soft, pliable cobwebby tissue thatcushions and protects the bodys

    organs it wraps

    Holds internal organs together and intheir proper positions

    Under microscope: matrix appears asempty space, reservoir of water andsalts

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    When a body region is inflamed, the areolar tissue in the area soaks

    up the excess fluid like a sponge, and the area swells andbecomes puffy.

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    Adipose cells are bundled together by connective tissue.

    Each cell appears as a clear space, representing the site of thelarge drop of lipid (fat) before it dissolved during preparation ofthe microscope slide.

    The nuclei appear as small disks on the periphery of cells.

    Functions to insulate the body, protect organs, and fuel storage

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    Consists of a delicate network of interwoven reticular fibers Forms the stroma(internal framework) which can support free blood

    cells in lymphoid organs (lymph nodes, spleen, & bone marrow)

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    Consists of blood cells surrounded by nonliving, fluid matrix

    called blood plasma Fibersonly visible during blood clotting

    Functions as a transport medium for materials

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    Muscle is a contractile tissue.

    There are three types of muscle:

    Skeletal

    Cardiac Smooth

    Main function is to produce movement.

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    Under voluntarycontrol

    Contracts to pull on bones or skin Produces gross body movements or facial expressions

    Characteristics of skeletal muscle cells

    Striated (stripe-like pattern)

    Multinucleate (more than one nucleus)

    Long, cylindrical

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    Under involuntarycontrol

    Found only in the heart Function is to pump blood

    Characteristics of cardiac muscle cells

    Cells are attached to other cardiac muscle cells at

    intercalateddisks

    Striated

    One nucleus/cell

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    Under involuntarymuscle

    Found in walls of hollow organs such as stomach, uterus, andblood vessels

    Characteristics of smooth muscle cells

    No visible striations

    One nucleus/cell Spindle-shaped cells

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    Nervous tissue, which occurs throughout the body, receives and

    transmits stimuli. It converts a stimulus, whether chemical or physical in nature,

    into an electrical impulse that is conducted by neurons.

    Nervous tissue also consists of glia, which are the various types

    of supporting cells in the nervous system.

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    The surface of the cerebellum is

    highly fissured. Outer layer is the molecular layer,

    which contains some glial cells but

    consists mostly of neuronal processes

    (dendrites and axons).

    Darkly stained area is the granularlayer and is composed mostly of

    nerve cell bodies of tiny granule cells

    (a neuron type) along with some

    larger Golgi cells (another neuron

    type). Between the molecular and granular

    layers lies the Purkinje layer.

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    Immunohistochemistry is used to reveal BrdU (brown), athymidine analog that is incorporated in cells undergoing S phase. Cellsstained brown were caught in the act of DNA synthesis. These cells arefound in the hippocampus, one of the only brain regions where newneurons are formed.

    (One example)

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    Immunofluorescence labeling shows new neurons in the hippocampus.

    Green is BrdU (the marker that labels cells undergoing S phase), red is a

    NeuN (a neuron-specific marker), and blue is GFAP (a glial marker). Cells

    co-labeled green and red are new neurons.

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