h-tert cell line
Post on 24-Feb-2016
32 Views
Preview:
DESCRIPTION
TRANSCRIPT
h-TERT cell line
An hTERT cell line is one that has been immortalized by inserting the hTERT (human telomerase reverse transcriptase) gene into the cells' DNA. This gene immortalizes cells by maintaining telomere ends. This prevents the telomere shortening of a cell's DNA which would otherwise cause the cells to senesce.
Recurrent SETBP1 mutations in childhood Acute myeloid
Leukemia
Nature Genet-ics
Nature Genet-ics
Primer name Primer sequences(5'-3')SETBP1-forward CCACTTTCAACACAGTTAGGTG SETBP1-Reverse TCTCGTGGTAGAAGGTGTAACTC
Amino acid number 778~979
Nature Genet-ics
C2903 (ser869)
C2903T/C (ser869)Patient No.44
Tumor type Number of samples Number of mutated samples
Percent mu-tated samples
childhood AML 55 0 0
top related