anidra and its management a review - gacollege.in goti.pdf · m.p.s.k.r. muthugala (2013) -...
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![Page 1: ANIDRA AND ITS MANAGEMENT A REVIEW - gacollege.in goti.pdf · M.P.S.K.R. Muthugala (2013) - Evaluation of Parasikayavanyadicapsule in the management of AnidraW.S.R. to insomnia](https://reader034.vdocuments.net/reader034/viewer/2022051718/5a7112947f8b9abb538c7e34/html5/thumbnails/1.jpg)
ANIDRA AND ITS MANAGEMENT – A REVIEW
INSTITUTE FOR POSTGRADUATE TEACHING AND RESEARCH IN AYURVEDAGUJARAT AYURVED UNIVERSITY
JAMNAGAR – 361 008
Scholar
Keval Goti
Guide
Kalpana Patel
Co-Guide
B.R.Patel
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PURPOSE
Ahara (diet), Nidra (sleep) and Brahmacharya (celibacy), are mentioned as three
Upastambhas (sub-supporting pillars) which play an important role in
maintaining the health. The inclusion of Nidra in three Upastambha signifies its
importance
It is stated that ;
happiness & sorrow,
growth & wasting,
strength & weakness,
virility & impotence and
knowledge & ignorance
as well as the existence of life and its cessation depend on the sleep.
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• A disease condition, where lack or less sleep (Nidra) seen is
known as Anidra which termed as Insomnia in Medical science.
• The modern medical science is still not having a definite treatment
for insomnia.
• Although hypnotics, sedative, anxiolytic, psychotropic are evolved
they have got their own limitations because of their hazardous
adverse effects.
• Therefore, such agents cannot be safe for a long period. Hence, it
becomes imperative to search out the drugs which are safe and
effective from natural systems of medicine like Ayurveda which
can help patients of insomnia.
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MATERIAL AND METHOD
In IPGT &RA, Jamnagar total 11 dissertation work has been
carried out on Anidra management till date, from which studies
carried out in the period 2001 to 2015 were analyzed and
presented in scientific manner.
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1. Comparative study on the effect of
Sneha Dhara and Jala Dhara in Anidra
(joshi chinmay- 2013)
1. Jatamansi Taila Dhara (Group A)
Drug: Jatamansi Taila.
Dose: 1 lit.
Duration: 45 minutes for 2 weeks
2. Jala Shirodhara (Group B)
Drug: Jala.( Luke warm water)
Dose: 1 lit.
Duration: 45 minutes for 2 weeks.
Jaladhara was performed about 45 minutes daily in the morning
for 2weeks
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Group-A
Jatamansi Taildhara
Group-B
Jaladhara
Total No. of patient 31 13 out of (15) 14 out of (16)
Complete Remission :
100% relief
0% 0%
Marked Improvement :
>75% relief
7.69% 0%
Moderate Improvement :
>50 % to 75 % relief
76.92% 85.71%
Mild Improvement : 25 %
to 50 % relief
15.38% 14.29%
Unchanged : <25 % or No
relief
0% 0%
Result of clinical study
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2. Anil kumar singh (2007) – A clinical study of Manasika
Bhavas in Anidra W.S.R to stress induced chronic insomnia
and its management with Mamsyadi Ghrita & Dashmoola
kwatha shirodhara–(kayachikitsa,m.D.Thesis)
1. Group-A.Mamsyadi Ghrita (MG)
Drug : Jatamamsi, Shankhapushpi, Ashwagandha, Tagar formulated as Ghrita.
Dose : 20 g twice a day orally
Anupana : Lukewarm water
Duration : 6 weeks
Follow up : one month
2. Group-B. Dashamula Kwatha –Shirodhara (SG)
• Drug : Dashamula Kwatha ,
Dose : 500 gm/day (2 liter kwatha form)
Duration : 21 Days
Follow up : one month.
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Group-A
Mamsyadi Ghrita Group
Group-B
Dashamula Kwatha
Dhara Group
Total No. of patient 30 15 8
Complete Remission :
100% relief
0% 0%
Marked Improvement :
76-99% relief
15% 25%
Moderate Improvement :
51 % to 75 % relief
46.67% 50%
Mild Improvement : 25 %
to 50 % relief
33.33% 25%
Unchanged : <25 % or No
relief
0% 0%
Result of clinical study
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3. Vansh bina (2008) – A clinical study on Manasika
Bhavas in Anidra W.S.R to stress induced insomnia
and its management with Tagaradi kwatha and
Mahishi Dugdha Shirodhara
(kayachikitsa,m.D.Thesis)
1.Group-A. Tagaradi Kwatha (TK)
Drug: Jatamamsi, Shankhapushpi, Ashwagandha, Tagar, Brahmi,
Draksha, Katuki, Parpatak, Dashamula, Musta,
Raktachandana, Amaltas formulated as Kwatha.
Dose: 40gm/day (Into two divided doses each of 20 gms)
Duration: 6 weeks
2. Group-B. Mahishi Dugdha Shirodhara (SG)
Drug: Mahishi Dugdha.
Dose: 1 liter Milk
Duration: 21 Days
Dugdhadhara was performed about 30 minutes daily in the morning
between 8:00 to 10:30 AM for 21 days with lukewarm Milk.
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Group-A
Tagaradi Kwatha
Group-B.
Mahishi Dugdha Shirodhara
Total No. of patient 31 17 10
Complete Remission :
100% relief
0% 0%
Marked Improvement :
>75% relief
0% 20%
Moderate Improvement :
>50 % to 75 % relief
23.53% 60%
Mild Improvement : 25 %
to 50 % relief
76.47% 20%
Unchanged : <25 % or No
relief
0% 0%
Result More effactive
Result of clinical study
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4. M.P.S.K.R. Muthugala (2013) - Evaluation of
Parasikayavanyadi capsule in the management of
Anidra W.S.R. to insomnia (kayachikitsa, M.D.
Thesis)
Parsikayavanyadi capsule
Parasikayavani-1/4 th part
Jatamansi -1 part
Shankhapushpi-7 Bhavanas of Svarasa
Kushmanda -7 Bhavanas of Svarasa
Grouping
Group P.V
(Parsikyavanadi Vati)
Group P.M
(along with allopathy
medicine)
Group P.C
(Placebo)
Dose 5 Capsules 5 Capsules 5 Capsules
Time At bed time At bed time At bed time
Anupana Luke warm water Luke warm water Luke warm water
Duration One month One month One month
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Parasikayavanyadi
capsule group P.V
Parasikayavanyadi
capsule group P.M:
Placebo
capsule
group P.C:
Total No. of patient 20 20 12
Complete Remission :
100% relief
0% 0% 0%
Marked Improvement :
>75% relief
0% 0% 8.33%
Moderate Improvement
: >50 % to 75 % relief
40% 55% 0%
Mild Improvement : 25
% to 50 % relief
50% 40% 0%
Unchanged : <25 % or
No relief
10% 5% 75%
Result of clinical study
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5. Nirmal Dhamini (2004) ‘Role of Manasika
Bhavas in Anidra and its management with
certain indigenous drugs and Shirodhara’.
1. Group A (Apamargadi Vati Group) :
Dose : 1 gm t.d.s.
Duration : 8 weeks
Anupana : With milk (buffalo)
2. Group B (Taila Dhara Group) :
Drug : Kshira Bala Taila
Duration : Shirodhara done for 30 min. daily in the morning for 2 weeks.
3.Group C (Combined Group)
In this group combined therapy has been given as mentioned in the groups above.
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Group A
(Apamargadi Vati
Group) :
• Group B
(Taila Dhara
Group) :
Group C
(Combined
Group)
Total No. of patient 20 20 12
Complete Remission :
100% relief
0% 0% 0%
Marked Improvement :
>75% relief
0% 62.50% 62.50%
Moderate Improvement :
>50 % to 75 % relief
85.70% 25% 37.50%
Mild Improvement : 25 % to
50 % relief
14.30% 12.50% 0%
Unchanged : <25 % or No
relief
0% 0% 0%
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6. A clinico comparative study of Madhukadi taila
Shiropichu and Pippalimoola Churna in the
management of Anidra w.S.R. To insomnia
Group A:
• Drug : Madhukadi Taila
• Form : Taila - Pichu
• Dose : 50 ml approximately
• Mode of administration : Local application(60minutes)
• Time : At morning
• Duration : 2 weeks
Group B:
• Drug : Pipplimoola
• Form : Churna
• Dose : 1 gm twice a day
• Mode of administration : Oral
• Time of administration : After food
• Anupana : Guda (Jaggery) 2 gm twice a day
• Duration : 4 weeks
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Group A Madhukadi
Taila Shiropichu
• Group B
Pipplimoola Churna
Total No. of patient 30 30
Complete Remission :
100% relief
0% 0%
Marked Improvement :
75% to 99%relief
20% 23.33%
Moderate Improvement
: 50 % to 75 % relief
53.33% 40%
Mild Improvement : 25
% to 50 % relief
20% 33.3%
Unchanged : 25 % or
No relief
6.67% 3.33%
result Highly significant insignificant
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7. Kalpesh panara (2013-2014) – A pharmaco
clinical evaluation of Beejapoorapatra (leave of
citrus medica linn.) W.S.R to insomnia.-
(Dravyaguna, ph.D thisis)
Group A:
• Drug :Powder of Beejapura
• Dose: 3g
• Anupana :Honey (5g)
• Route of administration :Oral
• Time of administration :Half an hour before bed time
• Duration of treatment :4 weeks
• Follow-up :2 weeks
Group B:
• Drug: leaves Powder of Jatamansi
• Dose: 3g
• Anupana :Honey (5g)
• Route of administration: Oral
• Time of administration: Half an hour before bed time
• Duration of treatment: 4 weeks
• Follow-up :2 weeks
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Group A
Powder of Beejapura
• Group B
Leaves Powder of
Jatamansi
Total No. of patient 33 33
Complete Remission :
100% relief
7% 13%
Marked Improvement :
76% to 99%relief
3% 9%
Moderate Improvement
: 51 % to 75 % relief
7% 19%
Mild Improvement : 26
% to 50 % relief
40% 59%
Unchanged : up to 25
% relief
43% 3.33%
result Highly significant
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8. Krutika joshi (2013-2014) – a pharmaco clinical
evaluation of Pippalimoola (root of piper longum)
W.S.R to insomnia.- (Dravyaguna, ph.D thesis)
Group A:
• Drug: Powder of Pipplimula
• Dose : 2g
• Anupana:Jaggery(5g)
• Route of administration :Oral
• Time : Half hour before bed time once at night
• Duration : 4 weeks
• Follow up: 2 weeks
Group B:
• Drug: Powder of Jatamansi rhizome
• Dose : 2g
• Anupana:Jaggery(5g)
• Route of administration :Oral
• Time : Half hour before bed time once at night
• Duration : 4 weeks
• Follow up: 2 weeks
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Group A
Powder of Pippalimula
• Group B
leaves Powder of
Jatamansi
Total No. of patient 28 28
Complete Remission :
100% relief
0% 0%
Marked Improvement :
76% to 99%relief
42.86% 3.57%
Moderate Improvement
: 501% to 75 % relief
57.14% 89.29%
Mild Improvement : 26
% to 50 % relief
0% 7.14%
Unchanged : up to25 %
relief
0% 0%
result Similar effect to
standard drug
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CONCLUSION
Therapies and formulation of the study which has givensignificant result were enlisted below.
Madhukadi Taila Dhara,
Mahishi Dugdhdhara,
Jatamansi powder,
Parsikyavanyadi capsule,
Mansyadi Ghrita,
Apamargadi Vati,
Jatamansi Tailadhara,
Dashmoola kwatha dhara
Madhukadi Taila Shiropichu
From the review work it can be concluded that internalmedication with Shirodhara is much effective in themanagement of Anidra.
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