arterial blood gases tutorial question

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    ABG TUTORIALSEMIRA ABDI

    M. Clin.Pharm (UKM), Bpharm (AAU)

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    1. The primary parameter for determining whether a

    patient has acidemia or alkalemia include

    A. Arterial PH

    B. Venous bicarbonate concentrationC. Arterial carbondioxide concentration

    D. A & B

    E. C& D

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    Arterial PH

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    2. The primary parameter for determining whether

    a patient has respiratory acidosis or alkalosis

    include

    A. Plasma haemoglobin.

    B. Percentage of oxygen saturation.

    C. Arterial carbondioxide concentration.

    D. A & B

    E. A & C

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    C. Arterial carbondioxide concentration.

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    3. In compensating for respiratory alkalosis, the

    body excretes more:

    A. ammonium ions.

    B. bicarbonate ions.C. dihydrogen phosphate ions.

    D. carbonic acid.

    E. hydrogen ions.

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    B. bicarbonate ions.

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    4. Given the following arterial blood gas values:

    PH :7.56

    PCO2 :31 mmHg

    HCO3 : 27 mEq/L

    PaO2: 56 mmHg

    What is (are) the most likely acid base state(s) in the patient?

    A. Acute respiratory alkalosis.

    B. Chronic respiratory alkalosis.

    C. Respiratory alkalosis and metabolic alkalosis.

    D. Respiratory acidosis and metabolic acidosis.

    E. Respiratory alkalosis and metabolic acidosis.

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    c. Respiratory alkalosis and metabolic alkalosis.

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    5. A 37-year-old man presents to hospital with

    shallow and slow breathing due to heroin

    overdose. His arterial blood gas results were as

    follows.

    Arterial blood gases (ABG):

    pH: 7.30

    PaCO2: 55 mm/Hg

    HCO3-: 27 mEq/L

    What kind of acid base disorder is he having?

    Is there adequate compensation?

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    Acute Respiratory Acidosis

    use winters formula to assess whether there is

    adequate compensation or not?

    PCO2= 1.5 (HCO3) 8 2

    = 1.5 (27) + 8 2

    = 48.5 2= (46.5- 50.5)

    There is no adequate compensation since the actual

    measure CO2 is 55.

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    6. A 77-year-old man presents with anxiety of

    psychosomatic origin. He has a very rapid

    breathing and slurred speech. His ABG results

    are as follows.

    Arterial blood gases (ABG):

    pH: 7.57

    PaCO2: 23 mmHg

    HCO3-: 21 mEq/L

    what kind of acid base problem is this patient having?

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    Acute Respiratory Alkalosis

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    7. A 70 year old man with history of CHF presents

    with increased shortness of breath and leg

    swelling.

    Arterial blood gases (ABG):

    pH : 7.24

    PCO2 : 60 mmHg

    PO2:52

    HCO3: 27

    What is the acid base disorder?

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    RESPIRATORYACIDOSISWITHINADEQUATE

    COMPENSATION(METABOLICALKALOSIS)

    The pH is low, (less than 7.35) therefore by

    definition, patient is acidemic.

    PCO2 and HCO3- are abnormal in the same

    direction, therefore less likely a mixed acid base

    disorder but not yet ruled out.

    PCO2 is high and represents acidosis and is

    consistent with the pH(Respiratory Acidosis).

    The high normal HCO3- must be the compensatory

    response.

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    8. A 23-year-old woman with gastroenteritis

    experiences nausea and vomiting. Arterial blood

    gas analysis is done 1 hour after the onset of

    symptoms. Which of the following sets of blood

    gases is most likely.

    A. pH 7.30; PCO2 50; HCO3 - 24

    B. pH 7.28; PCO2 40; HCO3 - 18

    C. pH 7.56; PCO2 40; HCO3 - 35

    D. pH 7.51; PCO2 45; HCO3 - 35

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    Choice D is the best answer.

    Vomiting causes loss of stomach acid leading to

    metabolic alkalosis. The rise in pH will inhibit the

    peripheral chemoreceptor for pH located in the

    carotid bodies leading to hypoventilation (increased

    PCO2), which is compensatory.

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    9. Point x indicates the acid base status of a healthy

    person at sea level. Point y indicates Data from a

    patients ABG analysis. Urine PH is 4.5. what is the

    most likely cause of the condition indicated by pointy?

    A. Adaptation to high altitude

    B. COPD

    C. Diabetic ketoacidosisD. Infusion of sodium lactate

    E. Severe prolonged vomiting

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    Answer is c. pH was sl igh t ly below 7.4

    (compensat ion is usual ly not complete and

    does not overshoot) AND the stem stated that

    ur ine pH was acidic. With respiratory alkalosis,

    the kidneys are excret ing bicarbonate and pH is

    no rmal ly alkal ine.

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    THANK YOU