bnp 1350 shows antitumour activity in advanced non-small-cell lung cancer

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Inpharma 1391 - 14 Jun 2003 BNP 1350 * shows antitumour activity in patients with refractory or relapsed non-small-cell lung cancer (NSCLC), according to data presented at the 39th Annual Meeting of the American Society of Clinical Oncology, which was held recently in Chicago, US. This phase II study involved a total of 49 evaluable patients with refractory or relapsed advanced NSCLC who received BNP 1350. Among the evaluable refractory population, 4% had a partial response and 48% experienced disease stabilisation. Corresponding values among the evaluable relapsed patients were 4% and 35%, respectively. The median survival was 5.6 months in the refractory patient group and 11.7 months in the relapsed patient group. The most frequently observed side effect of BNP 1350 was reversible bone marrow suppression. * BioNumerik Pharmaceuticals; phase II BioNumerik Pharmaceuticals Inc, et al. CALGB Presents Clinical Results on BioNumerik PharmaceuticalsNovel Antitumor Agent at the 39th Annual Meeting Of The American Society of Clinical Oncology (ASCO). Media Release : 2 Jun 2003. Available from: URL: http:// www.bionumerik.com 809021660 1 Inpharma 14 Jun 2003 No. 1391 1173-8324/10/1391-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

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Inpharma 1391 - 14 Jun 2003

■ BNP 1350* shows antitumour activity in patientswith refractory or relapsed non-small-cell lung cancer(NSCLC), according to data presented at the 39thAnnual Meeting of the American Society of ClinicalOncology, which was held recently in Chicago, US.This phase II study involved a total of 49 evaluablepatients with refractory or relapsed advanced NSCLCwho received BNP 1350. Among the evaluablerefractory population, 4% had a partial response and48% experienced disease stabilisation. Correspondingvalues among the evaluable relapsed patients were 4%and 35%, respectively. The median survival was 5.6months in the refractory patient group and 11.7months in the relapsed patient group. The mostfrequently observed side effect of BNP 1350 wasreversible bone marrow suppression.* BioNumerik Pharmaceuticals; phase II

BioNumerik Pharmaceuticals Inc, et al. CALGB Presents Clinical Results onBioNumerik Pharmaceuticals′ Novel Antitumor Agent at the 39th AnnualMeeting Of The American Society of Clinical Oncology (ASCO). MediaRelease : 2 Jun 2003. Available from: URL: http://www.bionumerik.com 809021660

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Inpharma 14 Jun 2003 No. 13911173-8324/10/1391-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved