cheminform abstract: diastereoselective synthesis of 1-aza-spiro[5.5]undecane skeleton
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2001 fused pyridine derivatives
fused pyridine derivativesR 0450
36 - 149Diastereoselective Synthesis of 1-Aza-spiro[5.5]undecane Skeleton.— The pipecolic acid derived sulfone (IV) is reported as intermediate for thesynthesis of various bicyclic enamines (VI). Cyclization of the furan derivative(VIc) via in situ generated N-acyliminium ions gives the spiro compound(VII) which possesses the backbone of histrinicotoxin alkaloids. — (DAVID,MARC; DHIMANE, HAMID; VANUCCI-BACQUE, CORINNE; LHOMMET,GERARD; Heterocycles 55 (2001) 5, 941-949; Lab. Chim. Heterocycl., CNRS,Univ. P. et M. Curie, F-75252 Paris, Fr.; EN)
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