cheminform abstract: three stereoisomers of a novel and selective μ-opioid analgesic

1996 structure structure (organic substances) K 9000 02 - 035 Three Stereoisomers of a Novel and Selective μ-Opioid Analgesic. — The conﬁgurations at the stereocenters of the title compounds (III) inﬂuence both the hydrogen-bonding behavior of the hydroxy group and the packing. The conformations of the central N-C-C(OH)-C-N chains are relevant to the pharmacological activity. — (IANELLI, S.; NARDELLI, M.; FRAIRE, C.; GRANCINI, G.; NAPOLETANO, M.; SANTANGELO, F.; Acta Crystallogr., Sect. C: Cryst. Struct. Commun. 51 (1995) 8, 1675-1680; Dip. Chim. Gen. Inorg., Chim. Anal., Chim. Fis., Univ. Studi Parma, I- 43100 Parma, Italy; EN) 1

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Page 1: ChemInform Abstract: Three Stereoisomers of a Novel and Selective μ-Opioid Analgesic

1996 structure

structure (organic substances)K 9000

02 - 035Three Stereoisomers of a Novel and Selective µ-Opioid Analgesic.— The configurations at the stereocenters of the title compounds (III) influenceboth the hydrogen-bonding behavior of the hydroxy group and the packing.The conformations of the central N-C-C(OH)-C-N chains are relevant to thepharmacological activity. — (IANELLI, S.; NARDELLI, M.; FRAIRE, C.;GRANCINI, G.; NAPOLETANO, M.; SANTANGELO, F.; Acta Crystallogr.,Sect. C: Cryst. Struct. Commun. 51 (1995) 8, 1675-1680; Dip. Chim. Gen.Inorg., Chim. Anal., Chim. Fis., Univ. Studi Parma, I- 43100 Parma, Italy; EN)

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