cyberinfrastructure for pharmaceutical r&d
TRANSCRIPT
Cyber Infrastructure for R&DDOI July 2004
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Cyberinfrastructure for
Pharmaceutical R&D
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Encounter at NSF, Spring 2003
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Cyberinfrastructure for
Pharmaceutical R&D
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Cyberinfrastructure for the
National R&D Community
Sangtae Kim, PhDPurdue University (on leave)
National Science Foundation (2004-06)
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Outline
• The Past (or how NSF changed the world …)
• The Present (from compute-centric to cyberinfrastructure)
• The Future (the network of things …)
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1980s
Arpanet - NSFNET merge to form the“Inter-Net”
NSFNETTCP/IP
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1990s
Arpanet - NSFNET merge to form the“Inter-Net”
“NSFNET” NCSA taps the www with the release ofMOSAIC, APACHE
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2004
Arpanet - NSFNET merge to form the“Inter-Net”
“TeraGrid” (ETF)goes live, fall 2004
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Network of Computers “the Grid”
Cambridge
NewcastleEdinburgh
Oxford
Glasgow
Manchester
CardiffSouthampton
London
Belfast
DL
RAL
UK
Amsterdam
BT provision
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NCSA Scientific Computing Environment - 32 TF
TeraGrid - MercuryIBM Itanium2 Linux Cluster
CopperIBM Power4 SMP Cluster
TungstenDell IA-32 Linux Cluster16.4 TF Peak + 1.2TF w/140 TB storage 2 TF10.6 TF, 230 TB storage
PlatinumIBM Pentium III
Linux Cluster1 TF
UniTree Archive ADIC Tape Library
TitanIBM Itanium Linux
Cluster1 TF
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Extensible Terascale Facility (ETF)
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Observations on the Present
• A golden age of computing, but …
• Scalability no longer a free ride on Moore’s Law• Contrast this with recent past: 32 CPU-hrs in 1997, takes 2 hrs in 2003
• Shift from compute-centric to balance with data• Emerging awareness of the importance of middleware
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Timeline: Past, Present and Future
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Pharmaceutical Informatics Architecture
Database Tier
Middle Ware (Business Rules)
Application (client) Tier
MS Office / Windows cell phone/PDAs web browsers
J2EEC #
Databases
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NSF Middleware Initiative
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Cyberinfrastructure: SensorNetsThe Network of Things
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Observations for the Future
• The pace of change will accelerate• (incredible - in light of changes over the past decade, but true)
• “IT Does Not Matter”• but middleware does … and architecture does – watch the response to
Wal-Mart initiated RFID technology disruption (dispersion of the pack)
• Look for a new network paradigm: wireless, RFID …• Pending revolution in manufacturing and supply chain