Evidence based medicine inmetastatic colorectal cancerworkshop17-18 October 2014 - Dubai, UAE

PRELIMINARY PROGRAMME

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Dear participant,

A warm welcome to all attending the “Evidence based medicine inmetastatic colorectal cancer workshop”.

I would like to inform you that as of 28 April 2014 the name of ourFoundation changed to EXCEMED – Excellence in MedicalEducation. The name change will not impact your registration statusin this or any other Foundation event.

This transition marks an exciting point in the evolution of theFoundation. We are proud to have provided world-class education tothousands of healthcare professionals over the past four decades -as a result, the Foundation has become synonymous with deliveryexcellence and high-impact CME.

As we further develop our scientific and geographical presence it isimportant to us that our name accurately reflects the independentnature of the education we provide; EXCEMED symbolises ourenduring mission to support the best possible outcomes for patientsthrough the medical education we offer. We take pride in ourcomplete dedication to the provision of CME - it is our sole focus andour passion.

I wish you an inspiring and successful learning experience in Dubai.

Yours Sincerely

Rachel ClarkCEO, EXCEMED

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AimClinical practice guidelines are an important tool in applying evidence-based medicine to patient care, especially in a complex and rapidlyevolving field such as oncology. Indeed, several lines of evidencedemonstrate that the use of guidelines in the practice of clinicaloncology can help in treatment decisions and ultimately lead tosignificant improvement in patient outcomes. However, even in thepresence of evidence-based recommendations, adherence to practiceguidelines varies widely across countries, due to cultural andorganizational differences. The aim of this live educational workshopis to review the current standards of care for metastatic colorectalcancer (mCRC) and to provide medical oncologists with insight intoemerging targets and new treatment options for mCRC patients. Inparallel, the applicability of international guidelines for mCRCpatients’ treatment across countries will be discussed, highlightingcritical issues that lead to differences in recommendations betweencountries.

Learning objectivesAfter attending this live educational workshop, learners will be able to:

• Describe relevant molecular pathways in mCRC

• Analyse current evidence-based recommendations for mCRCpatients treatment

• Evaluate notable variations in clinical practice guidelines for mCRCacross countries

Target audienceMedical oncologists coming from Eurasia as well as North-West andSouthern Africa who are experienced in managing metastaticcolorectal cancer patients and who want to gain insight into thebiology of the disease and new treatment options.

AccreditationAn application will be made to the EACCME® for CME accreditation ofthis EXCEMED programme “Evidence based medicine in metastaticcolorectal cancer workshop” to be held on 17-18 October 2014 inDubai, UAE.

EXCEMED adheres to the principles of the Good CME Practice group(gCMEp).

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Register to EXCEMED website:www.oncology.excemed.org

follow us onEXCEMED_Onco

http://twitter.com/EXCEMED_Onco

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Scientific organisersFortunato CiardielloDivision of Medical Oncology Department of Experimental and Clinical Medicine and Surgery F. Magrassi and A. Lanzara Second University of Naples Naples, Italy

Mohammed Ali JaloudiOncology ChairmanDepartment of OncologyTawam HospitalDubai, UAE

Scientific secretariatEXCEMED - Excellence in Medical EducationSalita di San Nicola da Tolentino, 1/b - 00187 Rome, Italy

Programme Manager: Simona PantaleoniT +39 06 420413 569 - F +39 06 420413 677E-mail: info@excemed.org

Specialist Medical Advisor: Cristina Raimondi

EXCEMED is a Swiss Foundation with headquarters in 14, Rue du Rhône, 1204 Geneva, Switzerland

Organising secretariatMeridiano Congress InternationalVia Sapri, 6 - 00185 Rome, ItalyCongress Coordinator: David H. SlangenT +39 06 88 595 250 - F +39 06 88595 234E-mail: d.slangen@meridiano.it

We value your opinion!We are continually trying to develop and improve oureducational initiative to provide you with cutting-edge learningactivities.

Before and after this workshop you will be receive onlinesurveys to help us tailor future educational initiatives evenbetter.

We thank you for participating!

Faculty membersDirk ArnoldKTB Klinik für TumorbiologieFreiburg, Germany

Andrés CervantesDepartment of Hematology and Medical Oncology University Hospital Valencia Valencia, Spain

Fortunato CiardielloDivision of Medical Oncology Department of Experimental and Clinical Medicine and Surgery F. Magrassi and A. Lanzara Second University of Naples Naples, Italy

Mohammed Ali JaloudiOncology ChairmanDepartment of OncologyTawam HospitalDubai, UAE

Heinz-Josef LenzClinical Research DepartmentGastrointestinal Cancers Program atUSC Norris Comprehensive Cancer CenterMedicine and Preventive Medicine Department Keck School of MedicineUniversity of Southern California Los Angeles, CA, USA

Nicola NormannoResearch DepartmentCell Biology and Biotherapy UnitINT Fondazione G. PascaleNaples, Italy

Graeme PostonDepartment of Hepatobiliary SurgeryNorth Western Hepatobiliary CentreAintree University Hospitals Foundation TrustLiverpool, UK

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Practice sessions moderatorsShouki BazarbashiDepartment of Medicine Alfaisal UniversityDepartment of Medical OncologyKing Faisal Specialist Hospital and Research Centre Riyadh, Arabia Saudita

Yasser Abdel KaderCairo UniversityCairo, Egypt

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Scientificprogramme

Scientific programme

Friday, 17 October 2014

08.50 EXCEMED opening

09.00 Scientific organisers introduce the workshopF. Ciardiello (Italy) - M.A. Jaloudi (UAE)

Chair: F. Ciardiello (Italy)

09.10 KN1: Precision medicine in mCRC: where are we now? M.A. Jaloudi (UAE)

09.40 L1: Relevant molecular pathways and the search forpredictive biomarkers for treatment of mCRCN. Normanno (Italy)

10.20 Question time

15.40 Coffee break

Chair: M.A. Jaloudi (UAE)

11.00 L2: Treatment options for first-line treatment of mCRC F. Ciardiello (Italy)

11.20 L3: Options after first-line treatment: second-linetreatment and beyond for mCRC D. Arnold (Germany)

12.00 IRT: Selecting an optimal treatment strategy for mCRCacross multiple lines of therapies All faculty members

13.00 Lunch

Session I

Session II

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Legend

L : Lecture; KN : Keynote lecture; : Question time; WG : Working Group;IRT : Interactive round table

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Chair: F. Ciardiello (Italy)

15.00 L4: Multimodality treatment for liver metastases fromcolorectal cancer and how to integrate targetedtherapies in the surgical management G. Poston, (UK)

15.40 WG1: Clinical case discussionS. Bazarbashi (Saudi Arabia)Y.A. Kader (Egypt)

17.10 Report from working groupsS. Bazarbashi (Saudi Arabia)Y.A. Kader (Egypt)

17.30 End of the first day

Session III

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Saturday, 18 October 2014

Chair: M.A. Jaloudi (UAE)

09.00 Highlights and summary from the first day

09.15 WG2: Clinical case discussionS. Bazarbashi (Saudi Arabia)Y.A. Kader (Egypt)

10.45 Report from working groupsS. Bazarbashi (Saudi Arabia)Y.A. Kader (Egypt)

11.05 Coffee break

Chair: F. Ciardiello (Italy)

11.25 L5: Critical review of international guidelines for mCRCA. Cervantes (Spain)

11.45 L6: Critical issues in the treatment of mCRC - Europe, United States and Middle East: a directcomparison F. Ciardiello (Italy) - M.A. Jaloudi (UAE) - A. Cervantes (Spain) - H. Lenz (USA)

12.30 KN2: Optimizing the treatment of mCRC: futuredirections H. Lenz (USA)

13.00 Closing remarks

13.10 End of the workshop

Session IV

Session V

Call for clinical cases

EXCEMED, together with the Scientific Organiser, are inviting submissionsof clinical case studies from participants to be presented and analysedduring the live educational workshop in Dubai.

Authors are requested to send the clinical case in PowerPoint format bye-mail to simona.pantaleoni@excemed.org by 1 October 2014.

EXCEMED’s medical team will review submissions and select thesuccessful clinical cases.

Format and structure

Clinical cases must be written in English and cover a maximum of sevenPowerPoint slides. The potential presentation must be exclusivelydedicated to the selected clinical case and last up to ten minutes.

Please use size 14 Calibri font type, according the following structure:

1. Clinical History:• Patient medical history• History of present illness• Diagnosis

2. Definition of treatment strategy (1)

3. Definition of treatment strategy (2)

4. Clinical course

5. Clinical questions and discussion points

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General information

VenueThis live educational workshop will be held at:Radisson Blu Hotel Dubai Deira CreekBaniyas Road - P.O. Box 476Dubai, UAE

LanguageThe official language of this live educational workshopwill be English.

Registration fee The registration fee is . . . . . . . . . . . . . . . . . . . . . . . . A 340,00.

This fee includes:• Scientific sessions• Coffee breaks and luncheons• Dinner on 17 October 2014• Educational materials• Certificate of attendance

Registration fee without dinner is . . . . . . . . . . . . . . A 260,00.

For more information on accommodation and registration pleasecontact:

David H. Slangen c/o Meridiano Congress InternationalE-mail: d.slangen@meridiano.it

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Take a look at the oncology sectionof the EXCEMED website

EXCEMED has made a strong commitment to medical education inoncology and is developing live events such as workshops, expertmeetings and preceptorships, online activities, and otherprogrammes that will focus on key issues in oncology and themultidisciplinary approaches to patient management.

Visit the oncology section:

www.oncology.excemed.organd register to access free e-learning activities and receive updateson new events and resources.

All EXCEMED programmes are organized solely to promote the exchange anddissemination of scientific and medical information. No forms of promotionalactivities are permitted. This programme is made possible thanks to an educationalgrant received from Merck Serono.

EXCEMED - Excellence in Medical EducationHeadquarters14, Rue du Rhône - 1204 Geneva, SwitzerlandRepresentative OfficeSalita di San Nicola da Tolentino 1/b - 00187 Rome, ItalyT +39 06 420413 1 - F +39 06 420413 677

Copyright © EXCEMED, 2014. All rights reserved.

Improving the patient's life through medical educationwww.excemed.org