Sakina Rubab

Doctor of Veterinary Medicine

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Picornaviridae

Aphthovirus

/Rhinovirus

7 serotypes (A, O,

C, Asia-I, SAT-1,

SAT-2, SAT-3), 60+

subtypes

Similar symptoms and

lesions produced by

different types

Immunity lost for 6

months

No cross immunity

In Pakistan: Asia-1

and O type (A,O,

Asia-I: 2012)

Most contagious agent

known in veterinary or

human medicine

OIE list A disease

cattle

buffaloes

yaks

sheep

goat

swine

camels

llamas

vicunas

Direct contact faeces, urine, saliva,

artificial insemination

Indirect contact utensils, water etc.

Occurs in winter season

Birds, Man, other animals

by shoes, by bedding of the

animals, skins, hides and even

different birds

Replication of virus in

i. Pharynx

ii. Epi. of Mouth

iii. Epi. of feet

iv. Teats

Through

Ingestion,

inhalation air

borne,

mechanical

Virus Animal Respiratory tract

Viremia

Blood

saliva semen faeces

milk

urine nasal discharge

Fever

Heavy stringy or drooling salivation

Vesicles and ulcers in mouth tongue

mostly affected

Vesicles on feet, interdigital spaces

Vesicles on teat and udder

Sequela :panting

Abortion

Erosion of epithelium of rumen pillars

Tiger heart

History (Vaccination)

Enzyme Linked Immuno Sorbant Assay

(best)

Polymerase Chain Reaction

Complement Fixation Test

Milk production decreased

Mastitis

Lameness

Weight loss: meat production decreased

Estrous cycle affected

Abortion

Isolation of sick animal

Soft leafy diet

Wash mouth with 1% potassium

permanganate solution

Ointment for mouth vesicles: boric acid

and glycerin or somo gel, Abbott or

bonjela, Macter International,apply thrice a

day

Wash feet with 2% copper sulphate

solution

Smear pyodine or tincture iodine

Antibiotic Tribex, Vetcon @1ml/30kg, I/M

Melonac ICI @ 1ml/35kg, I/M

Megapyrine, Star @5-10ml/ large animal0.5-2ml/small animal,

I/M Vitamin B complex, Zakfas @ 15-20ml

large5-12ml small I/V

Lugol’s iodine solution, Lugosol ,Life 1-5

drops in water, t.i.d for panting

Teragen spray, Star 200g as required on

hoof and udder lesions

Hot bread with butter : ruptures vesicles

Water from tanneries on vesicles :dries

them

Vaccinate animals twice a year

Large : Feb and Sep

Small : April and Oct

Dosage: large 5ml

small 2m S/C

Aftebin, Ghazi Bros, against A an O strains

only

Aftovaxpur , Saadat and Merial, against

A,O and Asia 1

Decivac, Leads ,against A, O and Asia 1

http://www.pakdairyinfo.com/FMD.htmhttp://www.pakistantoday.com.pk/2012/09/23/

business/foot-and-mouth-disease-a-threat-to-dairy-industry/

http://www.agrovoice.com.pk/dr-afzal-presents-strategic-management-for-the-control-of-fmd-in-pakistan/

D.C Blood, J.A Henderson,1974,Veterinary Medicine ,page 475-482.

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