global patterns of linkage disequilibrium at the cd4 locus

14
Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human Origins S. A. Tishkoff; E. Dietzsch; W. Speed; A. J. Pakstis; J. R. Kidd; K. Cheung; B. Bonné-Tamir; A. S. Santachiara-Benerecetti; P. Moral; M. Krings; S. Pääbo; E. Watson; N. Risch; T. Jenkins; K. K. Kidd Science, New Series, Vol. 271, No. 5254. (Mar. 8, 1996), pp. 1380-1387. Stable URL: http://links.jstor.org/sici?sici=0036-8075%2819960308%293%3A271%3A5254%3C1380%3AGPOLDA%3E2.0.CO%3B2-W Science is currently published by American Association for the Advancement of Science. Your use of the JSTOR archive indicates your acceptance of JSTOR's Terms and Conditions of Use, available at http://www.jstor.org/about/terms.html. JSTOR's Terms and Conditions of Use provides, in part, that unless you have obtained prior permission, you may not download an entire issue of a journal or multiple copies of articles, and you may use content in the JSTOR archive only for your personal, non-commercial use. Please contact the publisher regarding any further use of this work. Publisher contact information may be obtained at http://www.jstor.org/journals/aaas.html. Each copy of any part of a JSTOR transmission must contain the same copyright notice that appears on the screen or printed page of such transmission. The JSTOR Archive is a trusted digital repository providing for long-term preservation and access to leading academic journals and scholarly literature from around the world. The Archive is supported by libraries, scholarly societies, publishers, and foundations. It is an initiative of JSTOR, a not-for-profit organization with a mission to help the scholarly community take advantage of advances in technology. For more information regarding JSTOR, please contact [email protected]. http://www.jstor.org Tue Feb 19 07:50:40 2008

Upload: others

Post on 16-Oct-2021

4 views

Category:

Documents


0 download

TRANSCRIPT

Page 1: Global Patterns of Linkage Disequilibrium at the CD4 Locus

Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern HumanOrigins

S. A. Tishkoff; E. Dietzsch; W. Speed; A. J. Pakstis; J. R. Kidd; K. Cheung; B. Bonné-Tamir; A.S. Santachiara-Benerecetti; P. Moral; M. Krings; S. Pääbo; E. Watson; N. Risch; T. Jenkins; K. K.Kidd

Science, New Series, Vol. 271, No. 5254. (Mar. 8, 1996), pp. 1380-1387.

Stable URL:

http://links.jstor.org/sici?sici=0036-8075%2819960308%293%3A271%3A5254%3C1380%3AGPOLDA%3E2.0.CO%3B2-W

Science is currently published by American Association for the Advancement of Science.

Your use of the JSTOR archive indicates your acceptance of JSTOR's Terms and Conditions of Use, available athttp://www.jstor.org/about/terms.html. JSTOR's Terms and Conditions of Use provides, in part, that unless you have obtainedprior permission, you may not download an entire issue of a journal or multiple copies of articles, and you may use content inthe JSTOR archive only for your personal, non-commercial use.

Please contact the publisher regarding any further use of this work. Publisher contact information may be obtained athttp://www.jstor.org/journals/aaas.html.

Each copy of any part of a JSTOR transmission must contain the same copyright notice that appears on the screen or printedpage of such transmission.

The JSTOR Archive is a trusted digital repository providing for long-term preservation and access to leading academicjournals and scholarly literature from around the world. The Archive is supported by libraries, scholarly societies, publishers,and foundations. It is an initiative of JSTOR, a not-for-profit organization with a mission to help the scholarly community takeadvantage of advances in technology. For more information regarding JSTOR, please contact [email protected].

http://www.jstor.orgTue Feb 19 07:50:40 2008

Page 2: Global Patterns of Linkage Disequilibrium at the CD4 Locus
Page 3: Global Patterns of Linkage Disequilibrium at the CD4 Locus
Page 4: Global Patterns of Linkage Disequilibrium at the CD4 Locus
Page 5: Global Patterns of Linkage Disequilibrium at the CD4 Locus
Page 6: Global Patterns of Linkage Disequilibrium at the CD4 Locus
Page 7: Global Patterns of Linkage Disequilibrium at the CD4 Locus
Page 8: Global Patterns of Linkage Disequilibrium at the CD4 Locus
Page 9: Global Patterns of Linkage Disequilibrium at the CD4 Locus
Page 10: Global Patterns of Linkage Disequilibrium at the CD4 Locus

You have printed the following article:

Global Patterns of Linkage Disequilibrium at the CD4 Locus and Modern Human OriginsS. A. Tishkoff; E. Dietzsch; W. Speed; A. J. Pakstis; J. R. Kidd; K. Cheung; B. Bonné-Tamir; A.S. Santachiara-Benerecetti; P. Moral; M. Krings; S. Pääbo; E. Watson; N. Risch; T. Jenkins; K. K.KiddScience, New Series, Vol. 271, No. 5254. (Mar. 8, 1996), pp. 1380-1387.Stable URL:

http://links.jstor.org/sici?sici=0036-8075%2819960308%293%3A271%3A5254%3C1380%3AGPOLDA%3E2.0.CO%3B2-W

This article references the following linked citations. If you are trying to access articles from anoff-campus location, you may be required to first logon via your library web site to access JSTOR. Pleasevisit your library's website or contact a librarian to learn about options for remote access to JSTOR.

References and Notes

4 Age of the Earliest Known Hominids in Java, IndonesiaC. C. Swisher; G. H. Curtis; T. Jacob; A. G. Getty; A. Suprijo; WidiasmoroScience, New Series, Vol. 263, No. 5150. (Feb. 25, 1994), pp. 1118-1121.Stable URL:

http://links.jstor.org/sici?sici=0036-8075%2819940225%293%3A263%3A5150%3C1118%3AAOTEKH%3E2.0.CO%3B2-N

4 Genetic and Fossil Evidence for the Origin of Modern HumansC. B. Stringer; P. AndrewsScience, New Series, Vol. 239, No. 4845. (Mar. 11, 1988), pp. 1263-1268.Stable URL:

http://links.jstor.org/sici?sici=0036-8075%2819880311%293%3A239%3A4845%3C1263%3AGAFEFT%3E2.0.CO%3B2-5

6 African Populations and the Evolution of Human Mitochondrial DNALinda Vigilant; Mark Stoneking; Henry Harpending; Kristen Hawkes; Allan C. WilsonScience, New Series, Vol. 253, No. 5027. (Sep. 27, 1991), pp. 1503-1507.Stable URL:

http://links.jstor.org/sici?sici=0036-8075%2819910927%293%3A253%3A5027%3C1503%3AAPATEO%3E2.0.CO%3B2-2

http://www.jstor.org

LINKED CITATIONS- Page 1 of 5 -

NOTE: The reference numbering from the original has been maintained in this citation list.

Page 11: Global Patterns of Linkage Disequilibrium at the CD4 Locus

8 Geographic Origins of Human Mitochondrial DNA: Phylogenetic Evidence from ControlRegion SequencesDavid R. Maddison; Maryellen Ruvolovo; David L. SwoffordSystematic Biology, Vol. 41, No. 1. (Mar., 1992), pp. 111-124.Stable URL:

http://links.jstor.org/sici?sici=1063-5157%28199203%2941%3A1%3C111%3AGOOHMD%3E2.0.CO%3B2-D

8 Human Origins and Analysis of Mitochondrial DNA SequencesAlan R. Templeton; S. Blair Hedges; Sudhir Kumar; Koichiro Tamura; Mark StonekingScience, New Series, Vol. 255, No. 5045. (Feb. 7, 1992), pp. 737-739.Stable URL:

http://links.jstor.org/sici?sici=0036-8075%2819920207%293%3A255%3A5045%3C737%3AHOAAOM%3E2.0.CO%3B2-M

8 The "Eve" Hypotheses: A Genetic Critique and ReanalysisAlan R. TempletonAmerican Anthropologist, New Series, Vol. 95, No. 1. (Mar., 1993), pp. 51-72.Stable URL:

http://links.jstor.org/sici?sici=0002-7294%28199303%292%3A95%3A1%3C51%3AT%22HAGC%3E2.0.CO%3B2-1

9 Resolution of the African Hominoid Trichotomy by Use of a Mitochondrial Gene SequenceMaryellen Ruvolo; Todd R. Disotell; Marc W. Allard; Wesley M. Brown; Rodney L. HoneycuttProceedings of the National Academy of Sciences of the United States of America, Vol. 88, No. 4.(Feb. 15, 1991), pp. 1570-1574.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819910215%2988%3A4%3C1570%3AROTAHT%3E2.0.CO%3B2-2

9 Recent African Origin of Modern Humans Revealed by Complete Sequences of HominoidMitochondrial DNAsSatoshi Horai; Kenji Hayasaka; Rumi Kondo; Kazuo Tsugane; Naoyuki TakahataProceedings of the National Academy of Sciences of the United States of America, Vol. 92, No. 2.(Jan. 17, 1995), pp. 532-536.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819950117%2992%3A2%3C532%3ARAOOMH%3E2.0.CO%3B2-P

http://www.jstor.org

LINKED CITATIONS- Page 2 of 5 -

NOTE: The reference numbering from the original has been maintained in this citation list.

Page 12: Global Patterns of Linkage Disequilibrium at the CD4 Locus

10 Absence of Polymorphism at the ZFY Locus on the Human Y ChromosomeRobert L. Dorit; Hiroshi Akashi; Walter GilbertScience, New Series, Vol. 268, No. 5214. (May 26, 1995), pp. 1183-1185.Stable URL:

http://links.jstor.org/sici?sici=0036-8075%2819950526%293%3A268%3A5214%3C1183%3AAOPATZ%3E2.0.CO%3B2-D

15 Genetic Absolute Dating Based on Microsatellites and the Origin of Modern HumansD. B. Goldstein; A. Ruiz Linares; L. L. Cavalli-Sforza; M. W. FeldmanProceedings of the National Academy of Sciences of the United States of America, Vol. 92, No. 15.(Jul. 18, 1995), pp. 6723-6727.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819950718%2992%3A15%3C6723%3AGADBOM%3E2.0.CO%3B2-E

19 A Molecular Time Scale for Human EvolutionA. C. Wilson; V. M. SarichProceedings of the National Academy of Sciences of the United States of America, Vol. 63, No. 4.(Aug. 15, 1969), pp. 1088-1093.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819690815%2963%3A4%3C1088%3AAMTSFH%3E2.0.CO%3B2-F

28 Molecular Genetics of Speciation and Human OriginsFrancisco J. Ayala; Ananias Escalante; Colm O'hUigin; Jan KleinProceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 15.(Jul. 19, 1994), pp. 6787-6794.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819940719%2991%3A15%3C6787%3AMGOSAH%3E2.0.CO%3B2-A

29 Intensity of Natural Selection at the Major Histocompatibility Complex LociYoko Satta; Colm O'hUigin; Naoyuki Takahata; Jan KleinProceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 15.(Jul. 19, 1994), pp. 7184-7188.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819940719%2991%3A15%3C7184%3AIONSAT%3E2.0.CO%3B2-Z

http://www.jstor.org

LINKED CITATIONS- Page 3 of 5 -

NOTE: The reference numbering from the original has been maintained in this citation list.

Page 13: Global Patterns of Linkage Disequilibrium at the CD4 Locus

31 Branching Pattern in the Evolutionary Tree for Human Mitochondrial DNAAnna Di Rienzo; Allan C. WilsonProceedings of the National Academy of Sciences of the United States of America, Vol. 88, No. 5.(Mar. 1, 1991), pp. 1597-1601.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819910301%2988%3A5%3C1597%3ABPITET%3E2.0.CO%3B2-%23

32 Reconstruction of Human Evolution: Bringing Together Genetic, Archaeological, andLinguistic DataLuigi Luca Cavalli-Sforza; Alberto Piazza; Paolo Menozzi; Joanna MountainProceedings of the National Academy of Sciences of the United States of America, Vol. 85, No. 16.(Aug. 15, 1988), pp. 6002-6006.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819880815%2985%3A16%3C6002%3AROHEBT%3E2.0.CO%3B2-N

32 Drift, Admixture, and Selection in Human Evolution: A Study with DNA PolymorphismsAnne M. Bowcock; Judith R. Kidd; Joanna L. Mountain; Joan M. Herbert; Luciano Carotenuto;Kenneth K. Kidd; Luca Cavalli-SforzaProceedings of the National Academy of Sciences of the United States of America, Vol. 88, No. 3.(Feb. 1, 1991), pp. 839-843.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819910201%2988%3A3%3C839%3ADAASIH%3E2.0.CO%3B2-M

32 African Origin of Human-Specific Polymorphic Alu InsertionsMark A. Batzer; Mark Stoneking; Michelle Alegria-Hartman; Hernan Bazan; David H. Kass;Tamim H. Shaikh; Gabriel E. Novick; Panayiotis A. Ioannou; W. Douglas Scheer; Rene J. Herrera;Prescott L. DeiningerProceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 25.(Dec. 6, 1994), pp. 12288-12292.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819941206%2991%3A25%3C12288%3AAOOHPA%3E2.0.CO%3B2-M

35 Mutational Processes of Simple-Sequence Repeat Loci in Human PopulationsA. Di Rienzo; A. C. Peterson; J. C. Garza; A. M. Valdes; M. Slatkin; N. B. FreimerProceedings of the National Academy of Sciences of the United States of America, Vol. 91, No. 8.(Apr. 12, 1994), pp. 3166-3170.Stable URL:

http://links.jstor.org/sici?sici=0027-8424%2819940412%2991%3A8%3C3166%3AMPOSRL%3E2.0.CO%3B2-7

http://www.jstor.org

LINKED CITATIONS- Page 4 of 5 -

NOTE: The reference numbering from the original has been maintained in this citation list.

Page 14: Global Patterns of Linkage Disequilibrium at the CD4 Locus

36 The Genetic Structure of Ancient Human PopulationsHenry C. Harpending; Stephen T. Sherry; Alan R. Rogers; Mark StonekingCurrent Anthropology, Vol. 34, No. 4. (Aug. - Oct., 1993), pp. 483-496.Stable URL:

http://links.jstor.org/sici?sici=0011-3204%28199308%2F10%2934%3A4%3C483%3ATGSOAH%3E2.0.CO%3B2-3

http://www.jstor.org

LINKED CITATIONS- Page 5 of 5 -

NOTE: The reference numbering from the original has been maintained in this citation list.