i. educational and professional history · i. educational and professional history a. list of...

CARVER COLLEGE OF MEDICINE CURRICULUM VITAE

Gail A Bishop

May 2014 I. EDUCATIONAL AND PROFESSIONAL HISTORY

A. List of institutions attended (earliest to most recent)

1977 BA (Biology) St Olaf College

1979 MS (Oncology) University of Wisconsin, Madison

1983 PhD (Cellular and Molecular Biology)

University of Michigan, Ann Arbor

Post Graduate

1983 - 1986 Post Doctoral (Immunology)

The University of North Carolina, Chapel Hill

Mentor: Haughton, Geoffrey

1986 - 1988 Post Doctoral (Immunology)

The University of North Carolina, Chapel Hill

Mentor: Frelinger, Jeffrey

B. Employment History

1988 - 1989 Research Assistant Professor

The University of North Carolina, Chapel Hill, Chapel Hill, NC

1989 - 1994 Assistant Professor

Department of Microbiology, The University of Iowa College of Medicine, Iowa City, IA

1990 - Present Faculty, Medical Scientist Training Program

The University of Iowa, Iowa City, IA

1990 - Present Research Health Science Specialist

Iowa City VAMC, Iowa City, IA

1990 - 1994 Assistant Professor, Division of Rheumatology

Department of Internal Medicine, The University of Iowa College of Medicine, Iowa City, IA

1993 - Present Faculty, Interdisciplinary Graduate Program in Immunology


1993 - Present Faculty, Interdisciplinary Graduate Program in Molecular & Cellular Biology


1994 - 1998 Associate Professor, Division of Rheumatology


1994 - 1998 Associate Professor

Deptartment of Microbiology, The University of Iowa College of Medicine, Iowa City, IA

Gail A Bishop - January 2014

College of Medicine CV format 04/00

1998 - 2013 Director, Interdisciplinary Graduate Program in Immunology


1998 - Present Professor


1998 - Present Professor

Department of Microbiology, The University of Iowa College of Medicine, Iowa City, IA

1999 - 2004 Director, Cellular Activation Group

The University of Iowa Cancer Center, Iowa City, IA

2001 - Present College of Medicine Distinguished Professor of Microbiology


2004 - Present Holden Chair of Cancer Biology


2004 - Present Associate Director for Basic Science Research

Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA

2004 - Present Co-Director, Cancer Immunology & Immunotherapy Group

Holden Comprehensive Cancer Center, The University of Iowa, Iowa City, IA

C. Honors, Awards, Recognitions, Outstanding Achievements

1973 Milwaukee Jaycees Scholarship Award

1973 Milwaukee Transport Company Scholarship Award

1975 - 1976 Winter Research Laboratory Undergraduate Fellowship

1978 - 1979 NIH Predoctoral Trainee

University of Wisconsin

1979 - 1982 NIH Predoctoral Trainee

The University of Michigan

1982 - 1983 Horace H. Rackham Predoctoral Fellowship

The University of Michigan

1983 - 1984 Lineberger Cancer Research Center Postdoctoral Fellowship

The University of North Carolina at Chapel Hill

1984 - 1986 Damon Runyon-Walter Winchel Cancer Fund Postdoctoral Fellowship

1987 - 1990 National Arthritis Foundation Investigator Award

1994 - 1997 Carver Foundation Fellowship

The University of Iowa

1997 Leadership Award

Autumn Immunology Conference



2001 College of Medicine Distinguished Professor of Microbiology

2003 Donald D. Dorfman Research Award for best cancer-related scientific paper

Holden Cancer Center

2003 Graduate College Outstanding Mentor Award

2004 Holden Chair in Cancer Biology

2006 Invited speaker

University of Iowa Graduate College Commencement

2007 Carver Research Program of Excellence Award

2009 “Iowa Women of Innovation” award for Academic Innovation and Leadership

Iowa Technology Association

2013

2014

Appointed as Senior Research Career Scientist

Veteran's Administration

Murphy Distinguished Lectureship, U. of Oklahoma College of Medicine

II. TEACHING

A. Teaching assignments

Classroom, Seminar, Teaching Laboratory

1989 - 1996 Advanced Topics in Immunology

Fall 1989 (25%), 1996 (40%)

1990 - 1995 Research Microbiology (100%)

Fall 1990-Spring 1994, Fall 1994-Spring 1995

1990 - 1993 General Microbiology

Fall 1990 (20%), 1991 (20%), 1992 (20%), 1993 (20%)

1991 - 2000 Problems in Microbiology (100%)

Spring 1991, 1992, 1993, Fall 1993-Summer 1994, Spring 1997, Fall 1999-Spring 2000

1991 Cell Biology (10%)

1991 - 2003 Honors Microbiology (100%)

Fall 1991-Spring 1992, Fall 1994-Spring 1995, Spring 1998, Fall 2002-Spring 2003

1992 - 1994 Laboratory Methods in Cellular Immunology (40%)

Spring 1992, Spring 1994

1994 Molecular Biology Research (100%)

1994 Research in Immunology (100%)

1994 - 2002 Immunology I

Fall 1994 (22%), 1996 (20%), 1997 (33%), 1998 (50%), 1999 (50%), 2000



(50%), 2001 (50%), 2002 (50%)

1995 - 2009 Immunology Case Report Discussions for MS1 students

1995-1996 (6 hrs), 1996-1997 (6 hrs), 1997-1998 (6 hrs), 1998-1999 (6 hrs), 1999-2000 (6 hrs), 2000-2001 (6 hrs), 2002-2003 (6 hrs), 2003-2004 (6 hrs), 2004-2005 (6 hrs), 2005-2006 (6 hrs), 2008-2009 (2 hrs)

2002 Molecular Biology Student Seminar

Spring 2002 (50%), Fall 2002 (1 session)

2002 - 2008 Graduate Immunology I

Fall 2002 (60%), 2004 (60%), 2005 (70%), 2006 (65%), 2007 (65%), 2008 (65%)

2004 Graduate Immunology II (20%)

2004 Principles in Molecular and Cell Biology

4 hours

2009 Advanced Problem Solving in Pharmacological Sciences (20%)

2010 - 2014 Graduate Immunology (65%; Course Director)

Spring 2010, 2011, 2012, 2013, 2014

2013 - 2014

Writing a Scientific Proposal (100%; Course Director)

Fall 2013, 2014 (13 hours)

B. Student Supervision

Graduate Students

1990 - 1995 Jonathan Harton - Graduate - Microbiology - Degree Objective: PhD

1990 - 1994 *Steven Louie - Graduate - Microbiology - Degree Objective: MS

1993 - 1995 *Dan Harms - Graduate - Microbiology - Degree Objective: MS

1994 - 2001 Mekhine Baccam - Graduate - Microbiology - Degree Objective: PhD

1995 - 2000 Ian Catlett - Graduate - Microbiology - Degree Objective: PhD

1995 - 1999 Yina Hsing - Graduate - Immunology - Degree Objective: PhD

1996 - 2001 Lisa Busch - Graduate - Molecular Biology - Degree Objective: PhD

1998 - 2001 Kevin Brown - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD

1999 - 2003 Sokol Haxhinasto - Graduate - Immunology - Degree Objective: PhD

2000 - 2006 Carissa Moore - Graduate - Immunology - Degree Objective: PhD

2001 - 2006 Rebecca Benson - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD

2004 - 2009 Zachary Kraus - Graduate - Immunology - Degree Objective: PhD

2005 - 2009 Anna Peters - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD



2006 - 2010 John Graham - Graduate - Immunology - Degree Objective: PhD

2007 - 2012 Kelly Arcipowski - Graduate - Molecular & Cellular Biology - Degree Objective: PhD

2008 – 2014 Claire Buchta - Graduate - Immunology - Degree Objective: PhD

2009 - Present Wai-Wai Lin - Graduate - Immunology - Degree Objective: PhD

2012 - Present Alicia Wallis - Graduate - Immunology - Degree Objective: PhD

2012 - Present Nurbek Mambetsariev - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD

Lab Rotation

1990 Heeyun Kim - Graduate - Microbiology - Degree Objective: PhD

1993 - 1994 Loren Erickson - Graduate - Immunology - Degree Objective: PhD

1993 Julie Olson - Graduate - Microbiology - Degree Objective: PhD

1993 Rashmi Ukhade - Graduate - Microbiology - Degree Objective: PhD

1994 Kazuko Takahashi - Graduate - Immunology - Degree Objective: PhD

1994 Kim Richardson - Graduate - Molecular Biology - Degree Objective: PhD

1995 Lichao Zhou - Graduate - Immunology - Degree Objective: PhD

1995 Susan Haney - Graduate/Medical - MSTP - Degree Objective: MD/PhD

1996 - 1997 Yiyun Li - Graduate - Immunology - Degree Objective: PhD

1996 David Kolwyck - Graduate - Microbiology - Degree Objective: PhD

1996 Karl Swanson - Graduate - Molecular Biology - Degree Objective: PhD

1998 Tracy Jo Pasieka - Graduate - Microbiology - Degree Objective: PhD

1999 - 2000 Timothy Doyle - Graduate - Microbiology - Degree Objective: PhD

1999 Brandon Porter - Graduate/Medical - MSTP - Degree Objective: MD/PhD

1999 Gail Mayfield - Graduate - Microbiology - Degree Objective: PhD

1999 Joy Crowther - Graduate - Immunology - Degree Objective: PhD

1999 Julie Negri - Graduate - Molecular Biology - Degree Objective: PhD

2000 Ajai Dandekar - Graduate/Medical - MSTP - Degree Objective: MD/PhD

2000 Xiyou Zhou - Graduate - Biosciences - Degree Objective: PhD

2001 Andy Chung - Graduate - Molecular Biology - Degree Objective: PhD

2001 Tara Hermann - Graduate - Immunology - Degree Objective: PhD

2002 - 2003 Christine Hsiao - Graduate - Molecular Biology - Degree Objective: PhD

2002 - 2003 Colleen Cowan - Graduate - Biosciences - Degree Objective: PhD

2002 Hana Itani - Graduate - Molecular Biology - Degree Objective: PhD

2003 - 2004 Noah Butler - Graduate - Immunology - Degree Objective: PhD

2003 Anna Peters - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD



2003 Brenda Boll - Graduate - Biosciences - Degree Objective: PhD

2003 Matthew Olson - Graduate - Microbiology - Degree Objective: PhD

2004 Jennifer Schmidt - Graduate - Biosciences - Degree Objective: PhD

2005 - 2006 Jessica Tanner - Graduate - Immunology - Degree Objective: PhD

2005 Emily Isaak - Graduate/Medical - MSTP

2005 Jennifer Sowa - Graduate - Biosciences - Degree Objective: PhD

2005 Nhat-Long Pham - Graduate/Medical - MSTP

2005 Ping Lu - Graduate - Immunology - Degree Objective: PhD

2005 Ross Fulton - Graduate - Microbiology - Degree Objective: PhD

2006 - 2007 Martina Maric - Graduate - Microbiology - Degree Objective: PhD

2007 - 2008 Mayumi Fukuda - Graduate - Microbiology - Degree Objective: PhD

2007 Kerton Victory - Graduate - Biosciences - Degree Objective: PhD

2007 Lindsey Brown - Graduate - Immunology - Degree Objective: PhD

2008 Daniel Fox - Graduate/Medical - MSTP - Degree Objective: MD/PhD

2009 - 2010 Catherine He - Graduate - Immunology - Degree Objective: PhD

2009 - 2010 Mark Schultz - Graduate - Molecular & Cellular Biology - Degree Objective: PhD

2009

2010

Emily Hemann - Graduate - Immunology - Degree Objective: PhD

Leigh Richardson – Graduate/Medical – MSTP - Degree Objective: MD/PhD

2010 - 2011 Farrah Steinke - Graduate - Immunology - Degree Objective: PhD

2010 - 2011 William Krangel - Graduate - Biosciences - Degree Objective: PhD

2010 Bao Vu - Graduate - Microbiology - Degree Objective: PhD

2010 Ernest Chivera - Graduate - Molecular & Cellular Biology - Degree Objective: PhD

2010 Kayla Weiss - Graduate - Immunology - Degree Objective: PhD

2011 - 2012 Breanna Scorza - Graduate - Immunology - Degree Objective: PhD

2011 Aldo Vacaflores - Graduate - Immunology - Degree Objective: PhD

2011 Jeffrey Recchia-Rife - Graduate - Molecular & Cellular Biology - Degree Objective: PhD

2012 - 2013 Alicia Wallis - Graduate - Biosciences - Degree Objective: PhD

2012 - 2013 Nurbeck Mambetsariev - Graduate/Medical - MSTP - Degree Objective: MD/PhD

2012 Allison Songstad - Graduate - Molecular & Cellular Biology - Degree Objective: PhD

2012 Brett Gross - Graduate - Immunology - Degree Objective: PhD

2012

2014

Farah Itani - Graduate - Immunology - Degree Objective: PhD

Tina Arkee - Graduate/Medical – MSTP - Degree Objective: MD/PhD



Master's Thesis Committee

1990 - 1994 *Steven Louie - Graduate - Microbiology - Degree Objective: MS

1993 - 1995 *Dan Harms - Graduate - Microbiology - Degree Objective: MS

2000 Yiyun Li - Graduate - Immunology - Degree Objective: MS

2009 Nikaela Yarbrough - Graduate - Microbiology - Degree Objective: MS

Postdoctoral Research Supervision

1995 - 2002 Bruce Hostager - Postdoctoral

1995 - 1996 Jonathan Harton - Postdoctoral

1997 - 2000 Sangita Jaluakar - Postdoctoral

2000 - 2005 Ping Xie - Postdoctoral

2000 - 2002 So-youn Woo - Postdoctoral

2003 - 2010 Melissa Munroe - Postdoctoral

2004 - 2010 Anthony Vanden Bush - Postdoctoral

2004 - 2006 Riad Rahhal - Postdoctoral

2006 - 2012 Jayakumar Poovassery - Postdoctoral

2006 - 2012 Joanne Hildebrand - Postdoctoral

2009 - 2012 Dima Decker - Postdoctoral

2010 - Present Zuoan Yi - Postdoctoral

2010 - 2012 Evelena Ontiveros - Postdoctoral

Summer Research Scholars

1990 Jeffrey Hwang - High School - SSTP

1995 Monica Embers - Undergraduate - Hughes Undergraduate

1996 Jennifer Villasenor - Undergraduate - Microbiology Summer Undergraduate

1997 Jason Downing - Undergraduate - Microbiology Summer Undergraduate

1998 Jennifer Louten - Undergraduate - Microbiology Summer Undergraduate

2000 - 2001 Christopher Bucach - Medical - Medical Student Summer Research Training Program - Degree Objective: MD

2002 Carissa Thomas - Undergraduate - Hughes Summer Undergraduate

2002 Robin Lehmann - Medical - Medical Student Summer Research Training Program - Degree Objective: MD

2003 Julia Meade - Undergraduate - Wellesley College research program

2003 Kyeorda Kemp - Undergraduate - NSF REU in Microbiology

2005 Paige Wiecinski - Undergraduate - NSF REU in Microbiology

2006 Ruben Medina - Undergraduate - NSF REU in Microbiology

2008 Jennifer Claudio - Undergraduate - McNair



2009 Jennifer Claudio - Undergraduate - SROP

2009 Siva Kasinathan - IDGP Summer

2013

2014

David Tregaskis - IDGP Summer

Daniel Frey – IDGP Summer

Supervised Research

2007 - 2010 Ahmad Halawi - Fellow - Internal Medicine

Joined lab for research portion of combined Heme-Onc/Allergy & Immunology fellowship

Thesis Committee

1990 *Jonathan Harton - Graduate - Microbiology - Degree Objective: PhD

1990 Debra Martin - Graduate - Biochemistry - Degree Objective: PhD

1991 James Mobley - Graduate - Microbiology - Degree Objective: PhD

1991 Karen Snapp - Graduate - Microbiology - Degree Objective: PhD

1992 Teresa Foy - Graduate - Microbiology - Degree Objective: PhD

1994 *Mekhine Baccam - Graduate - Microbiology - Degree Objective: PhD

1994 James Greer - Graduate - Microbiology - Degree Objective: PhD

1995 *Ian Catlett - Graduate - Microbiology - Degree Objective: PhD

1995 *Yina Hsing - Graduate - Immunology - Degree Objective: PhD

1995 Dana Mordue - Graduate - Microbiology - Degree Objective: PhD

1995 David Motto - Graduate - Physiology - Degree Objective: PhD

1995 Kelly Smith - Graduate - Microbiology - Degree Objective: PhD

1995 Naixi Chen - Graduate - Microbiology - Degree Objective: PhD

1996 *Lisa Busch - Graduate - Molecular Biology - Degree Objective: PhD

1996 Janet Vigna - Graduate - Microbiology - Degree Objective: PhD

1996 Karen Duus - Graduate - Microbiology - Degree Objective: PhD

1997 Kevin Latinis - Graduate - Immunology - Degree Objective: PhD

1997 Loren Erickson - Graduate - Immunology - Degree Objective: PhD

1997 Michael Musci - Graduate - Immunology - Degree Objective: PhD

1998 *Kevin Brown - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD

1999 *Sokol Haxhinasto - Graduate - Immunology - Degree Objective: PhD

1999 Shawn Rigby - Graduate - Microbiology - Degree Objective: PhD

2000 *Carissa Moore - Graduate - Immunology - Degree Objective: PhD

2000 Kazuko Takahashi - Graduate - Immunology - Degree Objective: PhD

2001 *Rebecca Benson - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD



2002 Chenguang Fan - Graduate - Molecular Biology - Degree Objective: PhD

2002 Demetrius Gravis - Graduate - Immunology - Degree Objective: PhD

2002 Kira Gantt - Graduate - Immunology - Degree Objective: PhD

Served as Mentor of Record

2004 *Zachary Kraus - Graduate - Immunology - Degree Objective: PhD

2004 Ajai Dandekar - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD

2004 Janet Hume - Graduate/Medical - Microbiology/MSTP - Degree Objective: MD/PhD

2004

2004

2005

Nilda Rodriguez - Graduate - Microbiology - Degree Objective: PhD

Sarah Ingersoll - Graduate - Immunology - Degree Objective: PhD


Carla-Maria Alexander - Graduate - Immunology - Degree Objective: PhD

2005 *Anna Peters - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD

2006 *John Graham - Graduate - Immunology - Degree Objective: PhD

2006 Cassy Cozine - Graduate - Immunology - Degree Objective: PhD

2007 Jennifer Barr - Graduate - Anatomy & Cell Biology - Degree Objective: PhD

2007 *Kelly Arcipowski - Graduate - Molecular & Cellular Biology - Degree Objective: PhD

2007 Noah Butler - Graduate - Immunology - Degree Objective: PhD

2007

2007

2007

Rebecca Van Oosten - Graduate - Immunology - Degree Objective: PhD


Gregory Esparza - Graduate - Immunology - Degree Objective: PhD

Rebekah Bartelt - Graduate - Microbiology - Degree Objective: PhD

2008 *Claire Buchta - Graduate - Immunology - Degree Objective: PhD

2008 Nicole Chapman - Graduate - Immunology - Degree Objective: PhD

Serving as Mentor of Record

2008 Daniel Sprague - Graduate/Medical - Microbiology/MSTP - Degree Objective: MD/PhD

2008 Eric Ring - Graduate - Bassoon Performance - Degree Objective: DMA

2008

2009

2009

Sean Connelly - Graduate - Immunology - Degree Objective: PhD

Deceased 12/2008; served as Mentor of Record

Siao-Yi Wang - Graduate - Immunology - Degree Objective: PhD


Kathryn Trandem - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD



2009 - Present Timothy Rosean - Graduate - Immunology - Degree Objective: PhD

2009 - Present *Wai-Wai Lin - Graduate - Immunology - Degree Objective: PhD

2010 - Present Farrah Steinke - Graduate - Immunology - Degree Objective: PhD


2010 - Present Lauren Workman - Graduate - Molecular & Cellular Biology - Degree Objective: PhD

2010 - Present Mahmood Bilal - Graduate - Immunology - Degree Objective: PhD

2012 - Present *Alicia Wallis - Graduate - Immunology - Degree Objective: PhD

2012 - Present *Nurbek Mambetsariev - Graduate/Medical - Immunology/MSTP - Degree Objective: MD/PhD

2013 – Present

2014 - Present

Brett Gross - Graduate - Immunology - Degree Objective: PhD


Michael Zhang – Microbiology/MSTP – Degree Objective: MD/PhD

Undergraduate Students

1991 - 1993 Aarthi Shenoy - Undergraduate - Microbiology

1991 Deeann Horton - Undergraduate - Microbiology

1991 Julie Meye - Undergraduate - Microbiology

1993 - 1994 Amy Van Hagen - Undergraduate - Microbiology

1993 - 1994 Kyle Huff - Undergraduate - Microbiology

1994 - 1995 David Dao - Undergraduate - Microbiology

1994 - 1995 Joanna Figge - Undergraduate - Microbiology

1994 Aarthi Shenoy - Undergraduate - Microbiology

1997 - 1998 Alison Wisse - Undergraduate - Microbiology

1998 Joshua Field - Undergraduate - Microbiology

1999 - 2000 Debbie Duster - Undergraduate - Microbiology

2000 - 2001 Russell Edelheit - Undergraduate - Microbiology

2001 - 2003 Jacob Simmons - Undergraduate - Microbiology

2002 - 2003 Aaron Kithcart - Undergraduate - Microbiology

2003 - 2005 Komal Shah - Undergraduate - Microbiology

2010 - 2011 Stephanie Segura - Undergraduate - IBA

2012 Robert Le Beau - Undergraduate - Microbiology

2013-2014

2014

Brett Hanson - Undergraduate – Microbiology

Taylor Dornbusch - Undergraduate – Microbiology

C. Other Teaching Contributions



Institutional Conferences, Grand Rounds, Journal Clubs, Etc.

1989 - Present Immunology Seminar

1989 - 1992 MHC Journal Club

1990 - Present Rheumatology Journal Club

1991 - 1992 B Cell Journal Club

1992 - 2013 General Immunology Journal Club

Run by Dr. Bishop

Teaching Committees

1990 - 1995 Department of Microbiology, Admissions Committee

1993 - Present Department of Microbiology, Graduate Studies Committee

1993 - Present Immunology Graduate Program, Executive Committee

1993 - Present Immunology Graduate Program, Seminar Series Committee

1993 - 1996 Departmental representative, MSTP Advisory Committee

1993 - 1994 Immunology Graduate Program, Curriculum Committee

1994 - Present Department of Microbiology, Executive Committee

1994 - 2000 Molecular Biology Graduate Program, Graduate Advisory Committee

1994 - 1998 Immunology Graduate Program, Graduate Studies Committee

1995 - 2001 Department of Microbiology, Curriculum Committee

1996 - 1999 Molecular Biology Comprehensive Exam Committee

1996 - 1997 COM Basic Sciences Committee on Teaching Portfolios

1997 - 1999 MSTP Executive Committee

1997 Chair, Interdisciplinary Biosciences Recruitment (ORB) Graduate Advisory Committee Chair

2001 - Present Biosciences Program Executive Committee

2001 - Present Department of Microbiology, Admissions Committee

2001 - Present MSTP Graduate Advisory Committee

2006 - 2011 Molecular Biology Graduate Program, Graduate Advisory Committee

Other Teaching Contributions

1990 - 1993 Prepared handout covering entire Immunology section of General Microbiology.

1992 Prepared course syllabus for Advanced Immunology

1994 - Present Prepare handouts for Graduate Immunology I and II (updated each year).

1994 Prepared course syllabus for Immunology I

1996 - 2000 Prepared case report for Immunology Case Analysis for M1 students.




1997 Instructional material for graduate students on how to prepare for a Comprehensive Exam (prepared for Microbiology and Immunology graduate programs.

1997 Prepared sample teaching portfolio for Basic Sciences Teaching Portfolio committee.




2001 Prepared document on writing a Comprehensive Exam proposal for graduate students.

2007 Prepared materials on T-B cell collaboration of American Assoc. of Immunologists Introductory Immunology Course.

2009 Developed PowerPoint presentation on How to Give a Scientific Talk.

2013 Developed new graduate course, Writing a Scientific Proposal, at the request of the Immunology graduate students

III. SCHOLARSHIP/PROFESSIONAL PRODUCTIVITY

A. Publications or creative works (earliest to most recent)

Peer-reviewed papers

1. Bishop GA, Dove WF. Semisyngeneic hybrid resistance to murine teratocarcinoma cells, Immunogenetics. 1980;10(4):383-93. PMID:22457930

2. Bishop GA, Schwartz SA. Enhancement of human natural killer cells by interferon requires RNA and protein synthesis, Clin Immunol Immunopathol. 1982 December;25(3):374-85. PMID:6186424

3. Bishop GA, Glorioso JC, Schwartz SA. Relationship between expression of herpes simplex virus glycoproteins and susceptibility of target cells to human natural killer activity, J Exp Med. 1983 May 1;157(5):1544-61. PMC:PMC2187020

4. Bishop GA, Glorioso JC, Schwartz SA. Role of interferon in human natural killer activity against target cells infected with HSV-1, J Immunol. 1983 October;131(4):1849-53. PMID:6194217

5. Bishop GA, Marlin SD, Schwartz SA, Glorioso JC. Human natural killer cell recognition of herpes simplex virus type 1 glycoproteins: specificity analysis with the use of monoclonal antibodies and antigenic variants, J Immunol. 1984 October;133(4):2206-14. PMID:6206157

6. Bishop GA, Haughton G. H-2 control of expression of an idiotype shared by normal B cells and a B-cell lymphoma, Immunogenetics. 1985;21(4):355-66. PMID:3922882



7. Bishop GA, Haughton G. Role of the LFA-1 molecule in B cell differentiation, Curr Top Microbiol Immunol. 1986;132:142-7. PMID:3539536

8. Bishop GA, Kümel G, Schwartz SA, Glorioso JC. Specificity of human natural killer cells in limiting dilution culture for determinants of herpes simplex virus type 1 glycoproteins, J Virol. 1986 January;57(1):294-300. PMC:PMC252726

9. Bishop GA, Haughton G. Induced differentiation of a transformed clone of Ly-1+ B cells by clonal T cells and antigen, Proc Natl Acad Sci U S A. 1986 October;83(19):7410-4. PMC:PMC386727

10. Bishop GA, McCurry L, Schwartz SA, Glorioso JC. Activation of human natural killer cells by herpes simplex virus type 1-infected cells, Intervirology. 1987;28(2):78-88. PMID:2832348

11. Bishop GA, Haughton G. Role of the interleukin 2 receptor in differentiation of a clone of Ly-1+ B cells, J Immunol. 1987 May 15;138(10):3308-13. PMID:3106480

12. Gorelick MH, Bishop GA, Haughton G, Pisetsky DS. Cyclosporine inhibition of CH series murine B-cell lymphomas, Cell Immunol. 1987 June;107(1):219-26. PMID:3495347

13. Bishop GA, McMillan MS, Haughton G, Frelinger JA. Signaling to a B-cell clone by Ek, but not Ak, does not reflect alteration of Ak genes, Immunogenetics. 1988;28(3):184-92. PMID:3137158

14. Badley JE, Bishop GA, St John T, Frelinger JA. A simple, rapid method for the purification of poly A+ RNA, Biotechniques. 1988 February;6(2):114-6. PMID:2908499

15. Jambou RC, Snouwaert JN, Bishop GA, Stebbins JR, Frelinger JA, Fowlkes DM. High-level expression of a bioengineered, cysteine-free hepatocyte-stimulating factor (interleukin 6)-like protein, Proc Natl Acad Sci U S A. 1988 December;85(24):9426-30. PMC:PMC282765

16. Bishop GA, Frelinger JA. Haplotype-specific differences in signaling by transfected class II molecules to a Ly-1+ B-cell clone, Proc Natl Acad Sci U S A. 1989 August;86(15):5933-7. PMC:PMC297745

17. Bishop GA, Pennell CA, Travis W, Haughton G, Frelinger JA. Antibodies specific for Ig idiotype, but not isotype, can substitute for antigen to induce IgM secretion by a B cell clone, Int Immunol. 1990;2(4):285-90. PMID:2278988



18. Harton JA, Litaker W, Frelinger JA, Bishop GA. Structure function analysis of the H-2 Abp gene, Immunogenetics. 1991;34(6):358-65. PMID:1748486

19. Bishop GA. Requirements of class II-mediated B cell differentiation for class II cross-linking and cyclic AMP, J Immunol. 1991 August 15;147(4):1107-14. PMID:1651356

20. Bishop GA, Hwang J. Use of a cellular ELISA for the detection of cell surface antigens, Biotechniques. 1992 March;12(3):326-30. PMID:1571137

21. Bishop GA. Signaling to a CD5+ B-cell clone through surface Ig and MHC class II molecules, Ann N Y Acad Sci. 1992 May 4;651:228-40. PMID:1376042

22. Parikh VS, Bishop GA, Liu KJ, Do BT, Ghosh MR, Kim BS, Tucker PW. Differential structure-function requirements of the transmembranal domain of the B cell antigen receptor, J Exp Med. 1992 October 1;176(4):1025-31. PMC:PMC2119374

23. Bishop GA, Waldschmidt TJ, Koretzky GA. The interaction of Ig and class II MHC mediated signaling in B cell lines and subsets of B cells from normal and autoimmune mice, J Cell Biochem. 1993;17:252.

24. Louie SW, Ramirez LM, Krieg AM, Maliszewski CR, Bishop GA. Endogenous secretion of IL-4 maintains growth and Thy-1 expression of a transformed B cell clone, J Immunol. 1993 January 15;150(2):399-406. PMID:8093458

25. Bishop GA, Ramirez LM, Koretzky GA. Growth inhibition of a B cell clone mediated by ligation of IL-4 receptors or membrane IgM, J Immunol. 1993 April 1;150(7):2565-74. PMID:8454843

26. Harton JA, Bishop GA. Length and sequence requirements of the cytoplasmic domain of the A beta molecule for class II-mediated B cell signaling, J Immunol. 1993 November 15;151(10):5282-9. PMID:8228224

27. Bishop GA, Ramirez LM, Waldschmidt TJ. Differential responses to Ig and class II-mediated signals in splenic B cell subsets from normal and autoimmune mice, Int Immunol. 1994 July;6(7):1049-59. PMID:7947456

28. Krieg AM, Yi AK, Matson S, Waldschmidt TJ, Bishop GA, Teasdale R, Koretzky GA, Klinman DM. CpG motifs in bacterial DNA trigger direct B-cell activation, Nature. 1995 April 6;374(6522):546-9. PMID:7700380



29. Bishop GA, Warren WD, Berton MT. Signaling via major histocompatibility complex class II molecules and antigen receptors enhances the B cell response to gp39/CD40 ligand, Eur J Immunol. 1995 May;25(5):1230-8. PMID:7539751

30. Louie SW, Ramirez LM, Harton JA, Bishop GA. Positive and negative regulation of Thy-1 expression on B lymphocytes by IL-4, Int Immunol. 1995 September;7(9):1497-503. PMID:7495757

31. Harton JA, Van Hagen AE, Bishop GA. The cytoplasmic and transmembrane domains of MHC class II beta chains deliver distinct signals required for MHC class II-mediated B cell activation, Immunity. 1995 September;3(3):349-58. PMID:7552999

32. Lambert LE, Berling JS, Thompson SD, Harton JA, Bishop GA, Choi E. Polymorphism in the beta chain of IAq versus IAp influences presentation of protein but not peptide antigens, Cell Immunol. 1995 October 15;165(2):202-10. PMID:7553884

33. Hostager BS, Hsing Y, Harms DE, Bishop GA. Different CD40-mediated signaling events require distinct CD40 structural features, J Immunol. 1996 August 1;157(3):1047-53. PMID:8757608

34. Li YY, Baccam M, Waters SB, Pessin JE, Bishop GA, Koretzky GA. CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells, J Immunol. 1996 August 15;157(4):1440-7. PMID:8759724

35. Olson JK, Bishop GA, Grose C. Varicella-zoster virus Fc receptor gE glycoprotein: serine/threonine and tyrosine phosphorylation of monomeric and dimeric forms, J Virol. 1997 January;71(1):110-9. PMC:PMC191030

36. Rokhlin OW, Bishop GA, Hostager BS, Waldschmidt TJ, Sidorenko SP, Pavloff N, Kiefer MC, Umansky SR, Glover RA, Cohen MB. Fas-mediated apoptosis in human prostatic carcinoma cell lines, Cancer Res. 1997 May 1;57(9):1758-68. PMID:9135020

37. Rokhlin OW, Hostager BS, Bishop GA, Sidorenko SP, Glover RA, Gudkov AV, Cohen MB. Dominant nature of the resistance to Fas- and tumor necrosis factor-alpha-mediated apoptosis in human prostatic carcinoma cell lines, Cancer Res. 1997 September 15;57(18):3941-3. PMID:9307276

38. Hsing Y, Hostager BS, Bishop GA. Characterization of CD40 signaling determinants regulating nuclear factor-kappa B activation in B lymphocytes, J Immunol. 1997 November 15;159(10):4898-906. PMID:9366415



39. Hsing Y, Bishop GA. Requirement for nuclear factor-kappaB activation by a distinct subset of CD40-mediated effector functions in B lymphocytes, J Immunol. 1999 March 1;162(5):2804-11. PMID:10072527

40. Busch LK, Bishop GA. The EBV transforming protein, latent membrane protein 1, mimics and cooperates with CD40 signaling in B lymphocytes, J Immunol. 1999 March 1;162(5):2555-61. PMID:10072495

41. Hostager BS, Bishop GA. Cutting edge: contrasting roles of TNF receptor-associated factor 2 (TRAF2) and TRAF3 in CD40-activated B lymphocyte differentiation, J Immunol. 1999 June 1;162(11):6307-11. PMID:10352240

42. Catlett IM, Bishop GA. Cutting edge: a novel mechanism for rescue of B cells from CD95/Fas-mediated apoptosis, J Immunol. 1999 September 1;163(5):2378-81. PMID:10452970

43. Baccam M, Bishop GA. Membrane-bound CD154, but not CD40-specific antibody, mediates NF-kappaB-independent IL-6 production in B cells, Eur J Immunol. 1999 December;29(12):3855-66. PMID:10601993

44. Jalukar SV, Hostager BS, Bishop GA. Characterization of the roles of TNF receptor-associated factor 6 in CD40-mediated B lymphocyte effector functions, J Immunol. 2000 January 15;164(2):623-30. PMID:10623803

45. Hostager BS, Catlett IM, Bishop GA. Recruitment of CD40 and tumor necrosis factor receptor-associated factors 2 and 3 to membrane microdomains during CD40 signaling, J Biol Chem. 2000 May 19;275(20):15392-8. PMID:10748139

46. Bishop GA, Hsing Y, Hostager BS, Jalukar SV, Ramirez LM, Tomai MA. Molecular mechanisms of B lymphocyte activation by the immune response modifier R-848, J Immunol. 2000 November 15;165(10):5552-7. PMID:11067909

47. Bishop GA, Ramirez LM, Baccam M, Busch LK, Pederson LK, Tomai MA. The immune response modifier resiquimod mimics CD40-induced B cell activation, Cell Immunol. 2001 February 25;208(1):9-17. PMID:11277614

48. Brown KD, Hostager BS, Bishop GA. Differential signaling and tumor necrosis factor receptor-associated factor (TRAF) degradation mediated by CD40 and the Epstein-Barr virus oncoprotein latent membrane protein 1 (LMP1), J Exp Med. 2001 April 16;193(8):943-54. PMC:PMC2193407

49. Catlett IM, Xie P, Hostager BS, Bishop GA. Signaling through MHC class II molecules blocks CD95-induced apoptosis, J Immunol. 2001 May 15;166(10):6019-24. PMID:11342618



50. Busch LK, Bishop GA. Multiple carboxyl-terminal regions of the EBV oncoprotein, latent membrane protein 1, cooperatively regulate signaling to B lymphocytes via TNF receptor-associated factor (TRAF)-dependent and TRAF-independent mechanisms, J Immunol. 2001 November 15;167(10):5805-13. PMID:11698454

51. Zhu N, Ramirez LM, Lee RL, Magnuson NS, Bishop GA, Gold MR. CD40 signaling in B cells regulates the expression of the Pim-1 kinase via the NF-kappa B pathway, J Immunol. 2002 January 15;168(2):744-54. PMID:11777968

52. Hostager BS, Bishop GA. Role of TNF receptor-associated factor 2 in the activation of IgM secretion by CD40 and CD120b, J Immunol. 2002 April 1;168(7):3318-22. PMID:11907088

53. Brown KD, Hostager BS, Bishop GA. Regulation of TRAF2 signaling by self-induced degradation, J Biol Chem. 2002 May 31;277(22):19433-8. PMID:11909853

54. Haxhinasto SA, Hostager BS, Bishop GA. Cutting edge: molecular mechanisms of synergy between CD40 and the B cell antigen receptor: role for TNF receptor-associated factor 2 in receptor interaction, J Immunol. 2002 August 1;169(3):1145-9. PMID:12133933

55. Baccam M, Woo SY, Vinson C, Bishop GA. CD40-mediated transcriptional regulation of the IL-6 gene in B lymphocytes: involvement of NF-kappa B, AP-1, and C/EBP, J Immunol. 2003 March 15;170(6):3099-108. PMID:12626566

56. Haxhinasto SA, Bishop GA. A novel interaction between protein kinase D and TNF receptor-associated factor molecules regulates B cell receptor-CD40 synergy, J Immunol. 2003 November 1;171(9):4655-62. PMID:14568940

57. Hostager BS, Haxhinasto SA, Rowland SL, Bishop GA. Tumor necrosis factor receptor-associated factor 2 (TRAF2)-deficient B lymphocytes reveal novel roles for TRAF2 in CD40 signaling, J Biol Chem. 2003 November 14;278(46):45382-90. PMID:12958312

58. Haxhinasto SA, Bishop GA. Synergistic B cell activation by CD40 and the B cell antigen receptor: role of B lymphocyte antigen receptor-mediated kinase activation and tumor necrosis factor receptor-associated factor regulation, J Biol Chem. 2004 January 23;279(4):2575-82. PMID:14604983

59. Barabanova YA, Kang HK, Myoung J, Kang B, Bishop GA, Kim BS. Role of the major histocompatibility complex class II transmembrane region in antigen presentation and intracellular trafficking, Immunology. 2004 February;111(2):165-72. PMC:PMC1782412

60. Xie P, Hostager BS, Bishop GA. Requirement for TRAF3 in signaling by LMP1 but not CD40 in B lymphocytes, J Exp Med. 2004 March 1;199(5):661-71. PMC:PMC2213302



61. Stunz LL, Busch LK, Munroe ME, Sigmund CD, Tygrett LT, Waldschmidt TJ, Bishop GA. Expression of the cytoplasmic tail of LMP1 in mice induces hyperactivation of B lymphocytes and disordered lymphoid architecture, Immunity. 2004 August;21(2):255-66. PMID:15308105

62. Xie P, Bishop GA. Roles of TNF receptor-associated factor 3 in signaling to B lymphocytes by carboxyl-terminal activating regions 1 and 2 of the EBV-encoded oncoprotein latent membrane protein 1, J Immunol. 2004 November 1;173(9):5546-55. PMID:15494504

63. Munroe ME, Bishop GA. Role of tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) in distinct and overlapping CD40 and TNF receptor 2/CD120b-mediated B lymphocyte activation, J Biol Chem. 2004 December 17;279(51):53222-31. PMID:15485859

64. Mukundan L, Bishop GA, Head KZ, Zhang L, Wahl LM, Suttles J. TNF receptor-associated factor 6 is an essential mediator of CD40-activated proinflammatory pathways in monocytes and macrophages, J Immunol. 2005 January 15;174(2):1081-90. PMID:15634933

65. Moore CR, Bishop GA. Differential regulation of CD40-mediated TNF receptor-associated factor degradation in B lymphocytes, J Immunol. 2005 September 15;175(6):3780-9. PMID:16148124

66. Wu S, Xie P, Welsh K, Li C, Ni CZ, Zhu X, Reed JC, Satterthwait AC, Bishop GA, Ely KR. LMP1 protein from the Epstein-Barr virus is a structural CD40 decoy in B lymphocytes for binding to TRAF3, J Biol Chem. 2005 September 30;280(39):33620-6. PMID:16009714

67. Andrade RM, Wessendarp M, Portillo JA, Yang JQ, Gomez FJ, Durbin JE, Bishop GA, Subauste CS. TNF receptor-associated factor 6-dependent CD40 signaling primes macrophages to acquire antimicrobial activity in response to TNF-alpha, J Immunol. 2005 November 1;175(9):6014-21. PMID:16237096

68. Bishop GA, Hostager BS. CD40 Molecule Page, AfCS Signaling Gateway, Nature Onlin. 2006:A000031.

69. Xie P, Hostager BS, Munroe ME, Moore CR, Bishop GA. Cooperation between TNF receptor-associated factors 1 and 2 in CD40 signaling, J Immunol. 2006 May 1;176(9):5388-400. PMID:16622006

70. Benson RJ, Hostager BS, Bishop GA. Rapid CD40-mediated rescue from CD95-induced apoptosis requires TNFR-associated factor-6 and PI3K, Eur J Immunol. 2006 September;36(9):2535-43. PMID:16897814



71. Bishop GA, Moore CR, Xie P, Stunz LL, Kraus ZJ. TRAF proteins in CD40 signaling, Adv Exp Med Biol. 2007;597:131-51. PMID:17633023

72. Munroe ME, Bishop GA. A costimulatory function for T cell CD40, J Immunol. 2007 January 15;178(2):671-82. PMID:17202327

73. Munroe ME, Arbiser JL, Bishop GA. Honokiol, a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis, J Immunol. 2007 July 15;179(2):753-63. PMID:17617564

74. Xie P, Stunz LL, Larison KD, Yang B, Bishop GA. Tumor necrosis factor receptor-associated factor 3 is a critical regulator of B cell homeostasis in secondary lymphoid organs, Immunity. 2007 August;27(2):253-67. PMC:PMC2084086

75. Rahhal R, Vanden Bush TJ, McLendon MK, Apicella MA, Bishop GA. Differential effects of Francisella tularensis lipopolysaccharide on B lymphocytes, J Leukoc Biol. 2007 October;82(4):813-20. PMID:17634278

76. Rowland SL, Tremblay MM, Ellison JM, Stunz LL, Bishop GA, Hostager BS. A novel mechanism for TNFR-associated factor 6-dependent CD40 signaling, J Immunol. 2007 October 1;179(7):4645-53. PMID:17878362

77. Vanden Bush TJ, Bishop GA. TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation, Eur J Immunol. 2008 February;38(2):400-9. PMC:PMC2951126

78. Xue H, Jing X, Bollenbacher-Reilley J, Zhao DM, Haring JS, Yang B, Liu C, Bishop GA, Harty JT, Leonard WJ. Targeting the GA binding protein beta1L isoform does not perturb lymphocyte development and function, Mol Cell Biol. 2008 July;28(13):4300-9. PMC:PMC2447136

79. Peters AL, Plenge RM, Graham RR, Altshuler DM, Moser KL, Gaffney PM, Bishop GA. A novel polymorphism of the human CD40 receptor with enhanced function, Blood. 2008 September 1;112(5):1863-71. PMC:PMC2518891

80. Kraus ZJ, Haring JS, Bishop GA. TNF receptor-associated factor 5 is required for optimal T cell expansion and survival in response to infection, J Immunol. 2008 December 1;181(11):7800-9. PMC:PMC2636746

81. Poovassery JS, Vanden Bush TJ, Bishop GA. Antigen receptor signals rescue B cells from TLR tolerance, J Immunol. 2009 September 1;183(5):2974-83. PMC:PMC2789010



82. Graham JP, Moore CR, Bishop GA. Roles of the TRAF2/3 binding site in differential B cell signaling by CD40 and its viral oncogenic mimic, LMP1, J Immunol. 2009 September 1;183(5):2966-73. PMC:PMC2747101

83. Kraus ZJ, Nakano H, Bishop GA. TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40, Proc Natl Acad Sci U S A. 2009 October 6;106(40):17140-5. PMC:PMC2761366

84. Vanden Bush TJ, Buchta CM, Claudio J, Bishop GA. Cutting Edge: Importance of IL-6 and cooperation between innate and adaptive immune receptors in cellular vaccination with B lymphocytes, J Immunol. 2009 October 15;183(8):4833-7. PMID:19801508

85. Tseng W, Lu J, Bishop GA, Watson AD, Sage AP, Demer L, Tintut Y. Regulation of interleukin-6 expression in osteoblasts by oxidized phospholipids, J Lipid Res. 2010 May;51(5):1010-6. PMC:PMC2853427

86. Peters AL, Stunz LL, Meyerholz D, Mohan C, Bishop GA. Latent membrane protein 1, the EBV-encoded oncogenic mimic of CD40, accelerates autoimmunity in B6.Sle1 mice, J Immunol. 2010 October 1;185(7):4053-62. PMC:PMC3048355

87. Munroe ME, Businga TR, Kline JN, Bishop GA. Anti-inflammatory effects of the neurotransmitter agonist Honokiol in a mouse model of allergic asthma, J Immunol. 2010 November 1;185(9):5586-97. PMC:PMC3197781

88. Hildebrand JM, Luo Z, Manske MK, Price-Troska T, Ziesmer SC, Lin W, Hostager BS, Slager SL, Witzig TE, Ansell SM, Cerhan JR, Bishop GA, Novak AJ. A BAFF-R mutation associated with non-Hodgkin lymphoma alters TRAF recruitment and reveals new insights into BAFF-R signaling, J Exp Med. 2010 November 22;207(12):2569-79. PMC:PMC2989778

89. Peters AL, Bishop GA. Differential TRAF3 utilization by a variant human CD40 receptor with enhanced signaling, J Immunol. 2010 December 1;185(11):6555-62. PMC:PMC3040440

90. Xie P, Kraus ZJ, Stunz LL, Liu Y, Bishop GA. TNF receptor-associated factor 3 is required for T cell-mediated immunity and TCR/CD28 signaling, J Immunol. 2011 January 1;186(1):143-55. PMC:PMC3044490

91. Arcipowski KM, Stunz LL, Graham JP, Kraus ZJ, Vanden Bush TJ, Bishop GA. Molecular mechanisms of TNFR-associated factor 6 (TRAF6) utilization by the oncogenic viral mimic of CD40, latent membrane protein 1 (LMP1), J Biol Chem. 2011 March 25;286(12):9948-55. PMC:PMC3060549

92. Vanden Bush TJ, Bishop GA. CDK-mediated regulation of cell functions via c-Jun phosphorylation and AP-1 activation, PLoS One. 2011 April 29;6(4):e19468. PMC:PMC3084876



93. Xie P, Poovassery J, Stunz LL, Smith SM, Schultz ML, Carlin LE, Bishop GA. Enhanced Toll-like receptor (TLR) responses of TNFR-associated factor 3 (TRAF3)-deficient B lymphocytes, J Leukoc Biol. 2011 December;90(6):1149-57. PMC:PMC3236554

94. Arcipowski KM, Bishop GA. Roles of the kinase TAK1 in TRAF6-dependent signaling by CD40 and its oncogenic viral mimic, LMP1, PLoS One. 2012;7(7):e42478. PMC:PMC3408473

95. Poovassery JS, Bishop GA. Type I IFN receptor and the B cell antigen receptor regulate TLR7 responses via distinct molecular mechanisms, J Immunol. 2012 August 15;189(4):1757-64. PMID:22786773

96. Arcipowski KM, Bishop GA. TRAF Binding Is Required for a Distinct Subset of In Vivo B Cell Functions of the Oncoprotein LMP1, J Immunol. 2012 December 1;189(11):5165-70. PMC:PMC3504128

97. Arcipowski KM, Stunz LL, Bishop GA. TRAF6 is a critical regulator of LMP1 functions in vivo, Int Immunol. 26:149-158, 2013. PMID:24170780

98. Yi Z, Stunz LL, Bishop GA. TNF receptor associated factor 3 plays a key role in development and function of invariant natural killer T cells, J Exp Med. 2013 June 3;210(6):1079-86. PMC:PMC3674694

99. Han SS, Tompkins VS, Son DJ, Kamberos NL, Stunz LL, Halwani A, Bishop GA, Janz S. Piperlongumine inhibits LMP1/MYC-dependent mouse B-lymphoma cells, Biochem Biophys Res Commun. 2013 July 12;436(4):660-5. PMC:PMC3749779

100. Jellusova J, Miletic AV, Cato MH, Lin WW, Hu Y, Bishop GA, Shlomchik MJ, Rickert RC. Context-Specific BAFF-R Signaling by the NF-κB and PI3K Pathways, Cell Rep. 2013 November 27;5(4):1022-35. PMID:24239354

101. Lin WW, Hildebrand JM, Bishop GA. A Complex Relationship between TRAF3 and Non-Canonical NF-κB2 Activation in B Lymphocytes, Front Immunol. 2013 December 20;4:477. PMC3868921

102. Jenkinson SR, Williams JA, Jeon H, Zhang J, Nitta T, Ohigashi I, Kruhlak M, Zuklys S, Sharrow S, Adams A, Granger L, Choi Y, Siebenlist U, Bishop GA, Hollander GA, Takahama Y, Hodes RJ. TRAF3 enforces the requirement for T cell cross-talk in thymic medullary epithelial development, Proc Natl Acad Sci USA. 2013 December 24;110(52):21107-12. PMC 3876204

103. Buchta CM, Bishop GA. TRAF5 Negatively Regulates TLR Signaling in B Lymphocytes, J Immunol. 2014 January 1;192(1):145-50. PMC:PMC3872259



104. Ontiveros, E.P., Halwani, A., Stunz, L.L., Kamberos, N., Olivier, A.K., Janz, S., and Bishop, G.A. A new model of LMP1-MYC interaction in B cell lymphoma. Leukemia and Lymphoma Early Online 1-7, 2014.

105. Yi, Z., Stunz, LL, and Bishop, GA. CD40-mediated maintenance of immune homeostasis in the adipose tissue microenvironment. Diabetes, in press, 2014.

106. Yi, Z., Lin, W., Stunz, LL, and Bishop, GA. TRAF3 restrains the lineage determination of thymic regulatory T cells by modulating IL-2 receptor signaling. Nature Immunology, in press, 2014.

107. Yi, Z., Stunz, LL, Lin, W and. TRAF3 regulates homeostasis of CD8+ central memory T cells. PLoS One, in press, 2014. Chapters

1. Arnold LW, Lutz PM, Pennell CA, Bishop GA, Corley RB, Haughton G, LoCascio NJ. B cell tumors as models of B lymphocyte differentiation. In: J.C. Cambier, editors. B Cell Differentiation. CRC Reviews. 1986. p. 110-27

2. Bishop GA, Frelinger JA. The class II molecule as a signal transmitter to the B cell. In: C.S. David, editors. Proceedings of the International Symposium on H-2 Antigens: Genes, Molecules, Function. Plenum Press, New York. 1988. p. 517-22

3. Bishop GA, Frelinger JA. Relationship between class II structure and B cell signaling. In: C. David, editors. Transgenic Mice and Mutants in MHC Research. Springer-Verlag, NY. 1990. p. 36-40

4. Bishop GA. MHC Class II. In: I.M. Roitt, P.J. Delves, editors. Encyclopedia of Immunology. Academic Press, London. 1998. p. 1040-5

5. Bishop GA, Hostager BS. TNF-R Family Signaling Complexes, Chapter 56. In: R. Bradshaw, E. Dennis, editors. Handbook of Cell Signaling. Elsevier Science. 2003.

6. Bishop GA, Moore CR, Xie P, Stunz LL, Kraus ZJ. TRAF proteins in CD40 signaling. In: H. Wu, editors. TRAFs. Landes Bioscience, TX. 2007.

7. Bishop GA, Hostager BS. Assembly of signaling complexes for TNF receptor family molecules, Chapter 50. Handbook of Cell Signaling. Academic Press, Inc.. 2009.

8. Hildebrand J, Xie P, Bishop GA. Chapter 5. Signal transduction by receptors for BAFF and APRIL. In: M. Cancro, editors. The BAFF/BLyS Family. Humana Press, NJ. 2010. p. 93-114



9. Decker DA, Hostager BS, Bishop GA. CD40 signaling. In: S. Choi, editors. Encyclopedia of Signaling Molecules. Spring Press. 2011.

Reviews

1. Bishop GA, Arnold LW, Haughton G. Antigen-specific B cell tumors of mice, Crit Rev Immunol. 1986;6(2):105-21. PMID:3524998

2. Bishop GA, Haughton G. Use of the CH lymphomas as models of murine B cell differentiation, Immunol Res. 1986;5(4):263-70. PMID:3110331

3. Haughton G, Arnold LW, Bishop GA, Mercolino TJ. The CH series of murine B cell lymphomas: neoplastic analogues of Ly-1+ normal B cells, Immunol Rev. 1986 October;93:35-51. PMID:3491037

4. Bishop GA, Hostager BS. Molecular mechanisms of CD40 signaling, Arch Immunol Ther Exp (Warsz). 2001;49(2):129-37. PMID:11348017

5. Bishop GA, Hostager BS. Signaling by CD40 and its mimics in B cell activation, Immunol Res. 2001;24(2):97-109. PMID:11594459

6. Bishop GA, Hostager BS. B lymphocyte activation by contact-mediated interactions with T lymphocytes, Curr Opin Immunol. 2001 June;13(3):278-85. PMID:11406358

7. Bishop GA, Hostager BS, Brown KD. Mechanisms of TNF receptor-associated factor (TRAF) regulation in B lymphocytes, J Leukoc Biol. 2002 July;72(1):19-23. PMID:12101258

8. Bishop GA, Busch LK. Molecular mechanisms of B-lymphocyte transformation by Epstein-Barr virus, Microbes Infect. 2002 July;4(8):853-7. PMID:12270732

9. Bishop GA, Haxhinasto SA, Stunz LL, Hostager BS. Antigen-specific B-lymphocyte activation, Crit Rev Immunol. 2003;23(3):149-97. PMID:14584878

10. Bishop GA, Hostager BS. The CD40-CD154 interaction in B cell-T cell liaisons, Cytokine Growth Factor Rev. 2003;14(3-4):297-309. PMID:12787567

11. Bishop GA. The multifaceted roles of TRAFs in the regulation of B-cell function, Nat Rev Immunol. 2004 October;4(10):775-86. PMID:15459669

12. Bishop GA. CD40 and its viral mimic LMP1, Modern Aspects of Immunobiology. 2005;16:6.



13. Bishop GA. Immunology at the University of Iowa, Immunol Res. 2007;39(1-3):1-3. PMID:17917050

14. Bishop GA, Xie P. Multiple roles of TRAF3 signaling in lymphocyte function, Immunol Res. 2007;39(1-3):22-32. PMID:17917053

15. Xie P, Kraus ZJ, Stunz LL, Bishop GA. Roles of TRAF molecules in B lymphocyte function, Cytokine Growth Factor Rev. 2008 July;19(3-4):199-207. PMC:PMC2495079

16. Peters AL, Stunz LL, Bishop GA. CD40 and autoimmunity: the dark side of a great activator, Semin Immunol. 2009 October;21(5):293-300. PMC:PMC2753170

17. Graham JP, Arcipowski KM, Bishop GA. Differential B-lymphocyte regulation by CD40 and its viral mimic, latent membrane protein 1, Immunol Rev. 2010 September;237(1):226-48. PMID:20727039

18. Hildebrand JM, Yi Z, Buchta CM, Poovassery J, Stunz LL, Bishop GA. Roles of tumor necrosis factor receptor associated factor 3 (TRAF3) and TRAF5 in immune cell functions, Immunol Rev. 2011 November;244(1):55-74. PMC:PMC3202299

19. Bishop GA. The power of monoclonal antibodies as agents of discovery: CD40 Revealed as a B lymphocyte costimulator, J Immunol. 2012 May 1;188(9):4127-9. PMID:22517864

20. Arcipowski KM, Bishop GA. TRAF6 as a critical regulator of B lymphocyte functions, Curr Top Immunol. 2013;14:45-52.

21. Bishop GA. The many faces of TRAF molecules in immune regulation, J Immunol. 2013 October 1;191(7):3483-5. PMID:24058190

22. Hostager BS, Bishop GA. CD40-Mediated Activation of the NF-κB2 Pathway, Front Immunol. 2013 November 15;4:376. PMC:PMC3828524

23. Stunz LL, Bishop GA. LMP1 and the B lymphocyte – a complex relationship. CRC Crit Rev Immunol 34 (3):177-198, 2014.

24. Yi Z, Lin, WW, Stunz LL, Bishop GA. Roles for TRAF3 in lymphocyte functions, Cytokine & Growth Factor Reviews. 2014:in press.



25. Buchta, CM, Bishop, GA. Toll-like receptor signaling to B lymphocytes: Functions and mechanisms. Immunol. Res., 2014, in press.

26. Yi, Z. and Bishop, GA. Regulatory role of CD40 in obesity-induced insulin resistance. Adipocyte, 2014, in press.

Abstracts

1. Bishop GA, Schwartz SA. Effects of 2'-deoxycoformycin and 2'-deoxyadenosine on human lymphocyte activation, American Association of Immunologists, Atlanta, GA. 1981;Fed Proc 40:4826.

2. Bishop GA, Schwartz SA. Metabolic requirements for interferon-enhanced human natural cytotoxicity, American Association of Immunologists, New Orleans, LA. 1982;Fed Proc 41:3120.

3. Bishop GA, Schwartz SA, Glorioso JC. Characteristics of human natural killer activity against target cells infected with Herpes simplex virus type 1, 6th Annual Herpesvirus Symposium, Cold Spring Harbor Laboratory, Cold Spring, NY. 1982 August.

4. Bishop GA, Glorioso JC, Schwartz SA. Association of Herpes-specific glycoproteins with susceptibility to natural killer cells, American Association of Immunologists. 1983;Fed Proc 42:437.

5. Bishop GA, Glorioso JC, Schwartz SA. Recognition by natural killer cells of viral glycoproteins on target cells infected with HSV-1, Annual Meeting of the American Society for Virology. 1983 July.

6. Bishop GA, Marlin SD, Schwartz SA, Glorioso JC. Analysis of the specificity of natural killer cells for HSV-1 infected targets, American Association of Immunologists, St Louis, MO. 1984;Fed Proc 43:1906.

7. Bishop GA, Kumel G, Schwartz SA, Glorioso JC. Clonal specificity of human natural killer cells for determinants of HSV-1 glycoproteins, 10th International Herpesvirus Symposium, Ann Arbor, MI. 1985 August.

Invited Speaker

8. Bishop GA, Haughton G. Induced differentiation of a B cell clone: role of surface immunoglobulin, class II antigen and IL-2 receptor, American Association of Immunologists, St Louis, MO. 1986;Fed Proc 45:714.

Invited Speaker

9. Bishop GA, Haughton G. Induced differentiation of a B cell clone by T cells and antigen, Midwinter Conference of Immunologists, Asilomar, CA. 1986 January.



10. Bishop GA, Haughton G. Requirements for antigen-specific, MHC-restricted differentiation of an Ly-1+ B cell clone, 6th International Congress of Immunology, Toronto, Canada. 1986 July.

11. Bishop GA, Frelinger JA. B cell signaling through class II MHC molecules is not chain-specific, Midwinter Conference of Immunologists, Asilomar, CA. 1987 January.

12. Bishop GA, Frelinger JA. The class II molecule as a signal transmitter to the B cell, International Symposium on H-2 Antigens: Genes, Molecules, Function, Bar Harbor, ME. 1987 June.

13. Bishop GA, Frelinger JA. Haplotype-specific differences in signaling by class II molecules, Midwinter Conference of Immunologists, Asilomar, CA. 1989 January.

14. Bishop GA, Frelinger JA. Sequence-specific differences in signaling efficiency by class II molecules, International Conference on Transgenic Mice and Mutants in MHC Research, Bar Harbor, ME. 1989 June.

15. Bishop GA, Frelinger JA. Differences between MHC haplotypes in B cell signaling by class II molecules, 7th International Congress of Immunologists, Berlin. 1989 August.

16. Bishop GA, Frelinger JA. Haplotype-specific differences in signaling by transfected class II molecules to a B cell clone, 18th Annual Autumn Immunology Conference. 1989 November.

17. Bishop GA, Pennell CA, Travis W, Haughton G, Frelinger JA. Antigen, anti-isotype, and anti-idiotype antibodies in B cell signaling, Midwinter Conference of Immunologists, Asilomar, CA. 1990 January.

18. Harton JA, Litaker RW, Bishop GA. Structure-function analysis of H-2 I-AP molecules, 19th Annual Autumn Immunology Conference, Chicago. 1990 November.

19. Bishop GA. Ig and class II-mediated signaling in CD5 B cells, New York Academy of Sciences Conference, "CD5 B Cells in Development and Disease," Miami, FL. 1991 June.

Invited Speaker

20. Louie SL, Ramirez LM, Bishop GA. IL-4 is an autocrine growth factor for a B cell clone, Midwinter Conference of Immunologists, Asilomar, CA. 1992 January.

21. Bishop GA, Harton JA. Effects of structural alterations of the MHC class II beta chain on class II-mediated B cell activation, 8th International H-2/HLA Workshop, Jekyl Island, GA. 1992 April.



Invited Speaker

22. Bishop GA, Waldschmidt T. Class II-mediated B cell subset activation, Fogarty International Center Conference, NIH, "Antibodies in Natural Immunity and Autoimmune Diseases". 1992 September.

23. Harton JA, Bishop GA. Effects of truncation of the MHC class II αβ molecule on class II-mediated signaling, Autumn Immunology Conference, Chicago, IL. 1992 November.

24. Harton JA, Bishop GA. Effects of truncation of class II β chains on signal transduction to B cells, American Association of Immunologists, Anaheim, CA. 1993;Fed Proc 52:4942.

25. Bishop GA, Waldschmidt TJ, Koretzky GA. The interaction of Ig and class II-mediated signaling in B cell lines and subsets of B cells from normal and autoimmune mice, Keystone Symposium on Molecular Basis of B Cell Differentiation, Taos, NM. 1993 February.

26. Harton JA, Bishop GA. An analysis of specific residues in the cytoplasmic tail of Aβ required for class II-mediated signaling, Autumn Immunology Conference, Chicago, IL. 1993 November.

27. Louie SW, Bishop GA. IL-4 mediated transcriptional control of B cell Thy-1 expression, Autumn Immunology Conference, Chicago, IL. 1993 November.

28. Baccam M, Ramirez LM, Koretzky GA, Bishop GA. Molecular characterization of negative IgM-mediated signaling in the B cell clone, CHB3, Autumn Immunology Conference, Chicago, IL. 1993 November.

29. Harton JA, Bishop GA. Regulation of class II-mediated B cell signaling, 5th International Conference on Lymphocyte Activation, Newport Beach, CA. 1994 February.

30. Harton JA, Bishop GA. Length and sequence requirements of the cytoplasmic domain of the A beta molecule for class II-mediated B cell signaling, 9th International H-2/HLA Workshop, Garda, Italy. 1994 May.

Invited Speaker

31. Van Hagen A, Harton JA, Bishop GA. A PCR-based technique used to generate a saturation library of point mutants in a defined region of an MHC gene, Autumn Immunology Conference, Chicago, IL. 1994 October.

32. Harton JA, Bishop GA. Evidence for the role of glycine (227) and proline (228) in the cytoplasmic tail of Ab in class II-mediated B cell signaling, Autumn Immunology Conference, Chicago, IL. 1994 October.



33. Harms DE, Harton JA, Ramirez LM, Krieg AM, Bishop GA. Regulation of expression of B7-1 and B7-2 in murine B lymphocytes, Autumn Immunology Conference, Chicago, IL. 1994 October.

34. Weiner G, Belani R, Woolridge JE, Bishop GA, Koretzky GA. Anti-idiotype antibody induces activation signals and upregulates B7-2 expression on a murine B-cell lymphoma, American Society for Hematology, Nashville, TN. 1994 December.

35. Krieg AM, Yi A, Waldschmidt TJ, Bishop GA. Immune stimulation by a CpG motif: mechanisms and potential applications, 2nd International Conference on Antisense Nucleic Acids, Garmisch-Partenkirchen, Germany. 1995 February.

36. Baccam M, Harms D, Hostager B, Harton J, Bishop GA. Characterization of CD40 signaling in B and T cell lines, 9th International Congress of Immunology, San Francisco, CA. 1995 July.

37. Harton JA, Van Hagen AE, Bishop GA. The cytoplasmic and transmembrane domains of MHC class II β chains deliver distinct signals required for class II-mediated B cell activation, 9th International Congress of Immunology, San Francisco, CA. 1995 July.

38. Harton JA, Huff KA, Embers M, Catlett IM, Baccam M, Bishop GA. Analysis of the roles of protein tyrosine kinases and cAMP-dependent kinase in class II-mediated B cell signaling, Autumn Immunology Conference, Chicago, IL. 1995 November.

39. Baccam M, Hostager BS, Harton JA, Bishop GA. Role of the cytoplasmic domain of CD40 in membrane Ig-mediated enhancement of CD40 signaling, Autumn Immunology Conference, Chicago, IL. 1995 November.

40. Hostager BS, Baccam M, Harton JA, Bishop GA. Structure-function analysis of the cytoplasmic domain of CD40, Autumn Immunology Conference, Chicago, IL. 1995 November.

41. Bishop GA, Hostager BS, Hsing Y, Harms DE. Distinct CD40 structural requirements regulate CD40-mediated signals, American Association of Immunologists, New Orleans, LA. 1996 June.

Selected for Oral Presentation

42. Rokhlin O, Bishop GA, Hostager B, Sidorenko S, Cohen M. Expression of Fas and CD40 in human prostatic carcinoma cell lines, American Association of Immunologists, New Orleans, LA. 1996 June.

43. Hsing Y, Hostager BS, Bishop GA. CD40 structural and molecular requirements for activation of NF-κB, Autumn Immunology Conference, Chicago, IL. 1996 November.



44. Baccam M, Hostager BS, Bishop GA. Enhancement of CD40 signaling by the B cell antigen receptor, Autumn Immunology Conference, Chicago, IL. 1996 November.

45. Hostager BS, Baccam M, Bishop GA. Structural features of CD40 involved in delivery of proximal and distal signals, Autumn Immunology Conference, Chicago, IL. 1996 November.

46. Olson JK, Bishop GA, Grose C. VZV FcR contains a YXXL motif important for tyrosine phosphorylation and endocytosis, Autumn Immunology Conference, Chicago, IL. 1996 November.

47. Hostager BS, Baccam M, Bishop GA. Structural features of CD40 involved in delivery of proximal and distal signals, Midwinter Conference of Immunologists, Pacific Grove, CA. 1997 January.

48. Hsing Y, Hostager BS, Bishop GA. Molecular characterization of CD40 cytoplasmic signaling determinants regulating NF-κB activation in B cells, American Association of Immunologists, San Francisco, CA. 1997 February.

49. Hsing Y, Hostager BS, Bishop GA. Characterization of CD40 signaling events regulating NF-κB in B cells, Autumn Immunology Conference, Chicago, IL. 1997 November.

50. Hostager BS, Bishop GA. Examining the role of TRAF3 in CD40 signaling, Autumn Immunology Conference, Chicago, IL. 1997 November.

51. Catlett I, Bishop GA. Interactions between Fas, MHC class II and CD40 signaling pathways, Autumn Immunology Conference, Chicago, IL. 1997 November.

52. Baccam M, Hostager BS, Bishop GA. Mechanisms involved in the interactions between the CD40 and BCR-mediated signaling pathways, Autumn Immunology Conference, Chicago, IL. 1997 November.

53. Busch LK, Bishop GA. The EBV transforming protein, LMP1 mimics CD40 signalingn, Autumn Immunology Conference, Chicago, IL. 1997 November.

54. Catlett IM, Bishop GA. Crosstalk between Fas, CD40, Class II MHC, and the BCR, Midwinter Conference of Immunologists, Pacific Grove, CA. 1998 January.

55. Hostager BS, Bishop GA. Role of TRAF3 in CD40 signaling, Midwinter Conference of Immunologists, Pacific Grove, CA. 1998 January.



56. Hsing Y, Bishop GA. Characterization of NF-κB-dependent and independent signaling functions of CD40 in B lymphocytes, American Association of Immunologists, San Francisco, CA. 1998 April.

57. Brown K, Bishop GA. Comparison of the cytoplasmic domains of CD40 and the EBV transforming protein LMP1 in B cell signaling, Autumn Immunology Conference, Chicago, IL. 1998 November.

58. Hostager BS, Bishop GA. How CD40-mediated antibody secretion is regulated by TRAF's 2 and 3, Autumn Immunology Conference, Chicago, IL. 1998 November.

59. Busch LK, Bishop GA. LMP1 mimics and enhances CD40 signaling, Autumn Immunology Conference, Chicago, IL. 1998 November.

60. Hsing Y, Bishop GA. NF-κB activation is required for a distinct subset of CD40-mediated B cell functions, Autumn Immunology Conference, Chicago, IL. 1998 November.

61. Baccam M, Bishop GA. Regulation of IL-6 production in B cells by CD40-mediated signaling, Autumn Immunology Conference, Chicago, IL. 1998 November.

62. Jalukar S, Hostager BS, Bishop GA. Role of TRAF6 in CD40 signaling to B lymphocytes, Autumn Immunology Conference, Chicago, IL. 1998 November.

63. Catlett IM, Bishop GA. The B cell antigen receptor blocks Fas-mediated apoptosis by preventing caspase activation, Autumn Immunology Conference, Chicago, IL. 1998 November.

64. Hostager BS, Bishop GA. Contrasting roles of TRAFs 2 and 3 in CD40-stimulated antibody secretion, AAI Annual Meeting, Washington, DC. 1999 April.

65. Hsing Y, Bishop GA. Distinct subsets of CD40-mediated B cell effector functions require NF-κB activation, AAI Annual Meeting, Washington, DC. 1999 April.

66. Catlett IM, Bishop GA. Early rescue of B cells from Fas-induced apoptosis, AAI Annual Meeting, Washington, DC. 1999 April.

67. Baccam M, Bishop GA. NF-κB activation is not sufficient, and binding of TRAFs 2 and 3 is not required for CD40-mediated IL-6 production in B cells, AAI Annual Meeting, Washington, DC. 1999 April.



68. Jalukar S, Hostager BS, Bishop GA. Role of TRAF6 in CD40-mediated B cell activation, AAI Annual Meeting, Washington, DC. 1999 April.

69. Catlett IM, Bishop GA. B cell receptor-mediated rescue of B cells from Fas-induced apoptosis, Autumn Immunology Conference, Chicago, IL. 1999 November.

70. Brown KD, Bishop GA. Contrasting signaling by the EBV oncogenic protein LMP1 and CD40: Implications for B cell activation, Autumn Immunology Conference, Chicago, IL. 1999 November.

71. Baccam M, Bishop GA. Membrane-bound CD154, but not CD40-specific antibody, mediates NF-kappaB-independent IL-6 production in B cells, Autumn Immunology Conference, Chicago, IL. 1999 November.

72. Hostager BS, Catlett IM, Bishop GA. Recruitment of CD40, TRAF2, and TRAF3 to membrane microdomains during CD40 signaling, Autumn Immunology Conference, Chicago, IL. 1999 November.

73. Busch LK, Bishop GA. Structure-function analysis of the LMP1 carboxyl terminus, Autumn Immunology Conference, Chicago, IL. 1999 November.

74. Hostager BS, Bishop GA. TRAF rafting in CD40 signaling, 8th International Congress on TNF and Related Molecules, Trondheim, Norway. 2000 March.

75. Brown KD, Hostager BS, Bishop GA. Differential signaling and TRAF degradation mediated by CD40 and the EBV oncoprotein LMP1, American Association of Immunologists, Seattle, WA. 2000 May.


76. Bishop GA, Hostager BS, Brown KD. TRAFs and rafts in signaling by CD40 and LMP1, 8th International Congress on TNF and Related Molecules, Trondheim, Norway. 2000 May.

Presented as an Invited Plenary Session Talk

77. Edelheit R, Hostager BS, Ramirez LM, Bishop GA. Characterization of CD40 signals required for induction of IgE, Autumn Immunology Conference, Chicago, IL. 2000 November.

78. Brown KD, Hostager BS, Bishop GA. Differential signaling and TRAF degradation mediated by CD40 and the EBV oncoprotein LMP1, Autumn Immunology Conference, Chicago, IL. 2000 November.

79. Haxhinasto S, Bishop GA. Molecular mechanisms of interaction between the BCR and CD40, Autumn Immunology Conference, Chicago, IL. 2000 November.



80. Busch LK, Bishop GA. Structure-function analysis of the LMP1 carboxyl terminus, Autumn Immunology Conference, Chicago, IL. 2000 November.

81. Zhu M, Ramirez LM, Lee R, Pelech S, Bishop GA, Gold M. CD40 signaling in B cells regulates the expression of pim-1 via the NF-κB pathway, American Association of Immunologists, Orlando, FL. 2001 April.


82. Hostager BS, Bishop GA. Modulation of CD40-mediated B cell activation by TNFR2 through TRAF2, American Association of Immunologists, Orlando, FL. 2001 April.


83. Busch LK, Bishop GA. Structure-function analysis of signaling to B cells by the oncogenic protein, LMP1, Keystone Conference on B Lymphocytes. 2001 April.

84. Bishop GA. Mechanisms of TRAF regulation in B lymphocyte signaling by CD40 and LMP1, Cytokine Odyssey, Maui, HI. 2001 November.

Presented as an Invited Plenary Session Talk

85. Moore C, Brown KD, Bishop GA. Regulation of CD40-mediated TRAF degradation in B cells, Autumn Immunology Conference, Chicago, IL. 2001 November.

86. Haxhinasto S, Bishop GA. Roles of threonine 234 and PKCμ in cooperation between BCR and CD40-mediated signaling, Autumn Immunology Conference, Chicago, IL. 2001 November.

87. Xie P, Hostager BS, Bishop GA. Use of TraF3-/- B cell lines to study the roles of TRAF3 in signaling by CD40 and LMP1, Autumn Immunology Conference, Chicago, IL. 2001 November.

88. Bishop GA. Molecular characterization of signaling differences between CD40 and LMP1, TNF Superfamily Conference, San Diego, CA. 2002 October.

Presented as Plenary Session Talk

89. Haxhinasto S, Hostager BS, Xie P, Bishop GA. Molecular mechanisms of synergy between CD40 and the BCR: Role for TRAFs 2 and 3 in receptor interaction, TNF Superfamily Conference, San Diego, CA. 2002 October.

90. Hostager BS, Rowland S, Bishop GA. Roles of TRAF2 in B cell signaling: Development and use of TRAF-deficient B cell lines, TNF Superfamily Conference, San Diego, CA. 2002 October.


91. Stunz L, Busch L, Waldschmidt T, Tygrett L, Bishop GA. B cell signaling by CD40 and its viral mimic LMP1: The LMP1 cytoplasmic tail causes an altered phenotype in transgenic mice, Autumn Immunology Conference, Chicago, IL. 2002 November.



92. Moore CR, Bishop GA. Examining the regulation of TRAF degradation in B lymphocytes, Autumn Immunology Conference, Chicago, IL. 2002 November.

93. Benson RJ, Catlett IM, Hostager BS, Bishop GA. Inhibition of CD95-mediated apoptosis by B cell activation signals, Autumn Immunology Conference, Chicago, IL. 2002 November.

94. Haxhinasto S, Hostager BS, Xie P, Bishop GA. Molecular mechanisms of synergy between CD40 and the BCR: Role for TRAFs 2 and 3 in receptor interaction, Autumn Immunology Conference, Chicago, IL. 2002 November.

95. Munroe ME, Hostager BS, Bishop GA. Role and molecular mechanisms of signaling to B lymphocytes by TNFR2, Autumn Immunology Conference, Chicago, IL. 2002 November.

96. Rowland S, Hostager BS, Haxhinasto S, Bishop GA. Roles of TRAF2 in B cell signaling: Development and use of TRAF-deficient B cell lines, Autumn Immunology Conference, Chicago, IL. 2002 November.

97. Xie P, Hostager BS, Bishop GA. The immune receptor CD40 and its viral mimic, the EBV-encoded oncoprotein LMP1, exhibit differential dependence on TRAF3 for signaling, Autumn Immunology Conference, Chicago, IL. 2002 November.

98. Stunz LL, Busch LK, Waldschmidt T, Tygrett L, Bishop GA. B cell signaling by CD-40 and its viral mimic LMP1: the LMP1 cytoplasmic tail causes an altered phenotype in transgenic mice, American Association of Immunologists, Denver, CO. 2003 May.


99. Xie P, Hostager BS, Bishop GA. Contrasting negative and positive roles for TRAF3 in signaling by CD40 vs. its oncogenic mimic LMP1, American Association of Immunologists, Denver, CO. 2003 May.

100. Moore CR, Bishop GA. Receptor-induced TRAF degradation in B lymphocyte signal regulation, American Association of Immunologists, Denver, CO. 2003 May.

101. Oxley K, Bishop GA. A comparison of signaling by TNFR superfamily molecules in B lymphocytes versus normal and malignant prostate cells, Autumn Immunology Conference, Chicago, IL. 2003 November.

102. Moore CR, Bishop GA. CD40-induced TRAF degradation depends upon both binding affinity and binding position, Autumn Immunology Conference, Chicago, IL. 2003 November.

103. Benson R, Bishop GA. Characterization of CD40-mediated rescue of B lymphocytes from CD95-mediated apoptosis, Autumn Immunology Conference, Chicago, IL. 2003 November.



104. Stunz LL, Busch LK, Waldschmidt T, Tygrett L, Bishop GA. Elevated IL-6 and autoantibody production in mice transgenically expressing the LMP1 cytoplasmic domain, Autumn Immunology Conference, Chicago, IL. 2003 November.

105. Larison KD, Simmons JA, Moore CR, Bishop GA. Role of TRAF3 in signaling to B lymphocytes via receptors for BAFF, Autumn Immunology Conference, Chicago, IL. 2003 November.

106. Munroe ME, Bishop GA. Signaling to B lymphocytes by CD40 and TNFR2, Autumn Immunology Conference, Chicago, IL. 2003 November.

107. Munroe ME, Bishop GA. A comparison of signaling mechanisms of CD40 and TNFR2 in B lymphocytes: Distinct and overlapping pathways, American Association of Immunologists, Washington, DC. 2004 April.

108. Benson R, Bishop GA. PI3-kinase is required for CD40-mediated protection of B cells from CD95-mediated apoptosis, American Association of Immunologists, Washington, DC. 2004 April.

109. Moore CM, Bishop GA. Receptor-induced TRAF degradation in B lymphocytes, American Association of Immunologists, Washington, DC. 2004 April.


110. Oxley K, Bishop GA. Membrane recruitment of TNFR family members in normal and malignant prostate cells, Conference on Genitourinary Malignancies, Iowa City, IA. 2004 June.

111. Munroe ME, Bishop GA. CD40 and TNFR2 activate NF-kB in distinct, TRAF2-dependent ways, International Congress of Immunology, Montreal, Canada. 2004 July.

112. Kraus Z, Bishop GA. A mutant TRAF2 lacking the C-terminal domain forms spontaneous aggregates in TRAF2-deficient B cells, Autumn Immunology Conference, Chicago, IL. 2004 November.

113. Benson R, Hostager BS, Bishop GA. CD40 rescue from CD95 apoptosis requires TRAF6 and PI3-kinase, Autumn Immunology Conference, Chicago, IL. 2004 November.

114. Stunz L, Bishop GA. Effects of co-expression of CD40 and LMP1 in vivo, Autumn Immunology Conference, Chicago, IL. 2004 November.

115. VandenBush A, Bishop GA. Interactions between innate and adaptive immune receptors in B cells, Autumn Immunology Conference, Chicago, IL. 2004 November.



116. Moore CR, Bishop GA. Receptor-induced TRAF degradation in B lymphocytes, Autumn Immunology Conference, Chicago, IL. 2004 November.

117. Xie P, Bishop GA. Roles of TRAF3 in signaling to B lymphocytes by CTAR1 and 2 of the EBV-encoded oncoprotein LMP1, Autumn Immunology Conference, Chicago, IL. 2004 November.

118. Munroe ME, Bishop GA. Signaling to T lymphocytes by CD40, Autumn Immunology Conference, Chicago, IL. 2004 November.

119. Xie P, Bishop GA. Exploration of signaling by TNFR superfamily members in B cells deficient in multiple TRAFs, American Association of Immunologists, San Diego, CA. 2005 April.


120. Stunz L, Bishop GA. In vivo interactions between CD40 and LMP1, American Association of Immunologists, San Diego, CA. 2005 April.

121. Munroe ME, Bishop GA. Anti-inflammatory effects of honokiol on CD40 and LMP1-mediated signaling, Autumn Immunology Conference, Chicago, IL. 2005 November.

122. VandenBush A, Bishop GA. Cooperation between CD40 and TLR signaling in B cells, Autumn Immunology Conference, Chicago, IL. 2005 November.

123. Kraus ZJ, Bishop GA. Function of TRAF molecules in the signal transduction of CD27 in B lymphocytes, Autumn Immunology Conference, Chicago, IL. 2005 November.

124. Benson RJ, Hostager BS, Bishop GA. Rapid CD40 and TLR9 rescue from CD95 apoptosis, Autumn Immunology Conference, Chicago, IL. 2005 November.

125. Moore CR, Bishop GA. Role of TRAFs in CD40-mediated isotype switching, Autumn Immunology Conference, Chicago, IL. 2005 November.

126. Moore CR, Bishop GA. Molecular mechanisms regulating TRAF degradation mediated by members of the TNFR superfamily, Keystone Meeting on B Lymphocytes, Keystone, CO. 2006 February.

127. Kraus ZJ, Bishop GA. Roles played by members of the TRAF family of adapter proteins in signaling by CD40 and CD27, Keystone Meeting on B Lymphocytes, Keystone, CO. 2006 February.



128. Xie P, Stunz LL, Larison KD, Yang B, Bishop GA. B cell-specific TRAF3-deficient mice exhibit expanded B cell compartments in secondary lymphoid organs, American Association of Immunologists, Boston, MA. 2006 May.


129. Stunz L, Bishop GA. Mechanisms of B cell autoimmunity in LMP1 transgenic mice, American Association of Immunologists, Boston, MA. 2006 May.


130. Peters A, Gaffney P, Bishop GA. A polymorphism in human CD40 correlates with autoimmunity and enhances B cell activation, Autumn Immunology Conference, Chicago, IL. 2006 November.

131. Kraus ZJ, Haring J, Harty JT, Bishop GA. A role for TRAF5 in CD8+ T cell responses, Autumn Immunology Conference, Chicago, IL. 2006 November.

132. Munroe ME, Bishop GA. Abrogation of inflammation by honokiol: GABA(A)-mediated alteration of CD40 and LMP1 signaling in B cells, Autumn Immunology Conference, Chicago, IL. 2006 November.

133. VandenBush A, Bishop GA. Cooperation between TLRs and CD40: Synergy in human and mouse B cell IL-6 production via regulation of c-Jun N-terminal kinase (JNK) and the phosphatase PP2A, Autumn Immunology Conference, Chicago, IL. 2006 November.

134. Rahhal R, VandenBush A, McLendon M, Apicella MA, Bishop GA. Differential effects of virulent F. tularensis LPS on human peripheral B lymphocytes, Society for Leukocyte Biology, San Antonio, TX. 2006 November.

135. Peters AL, Gaffney PM, Bishop GA. A polymorphism in human CD40 correlates with autoimmunity and enhances B cell activation, American Academy of Allergy, Asthma, & Immunology Annual Meeting, San Diego, CA. 2007 February.


136. Xie P, Stunz LL, Larison KD, Yang B, Bishop GA. A role for TRAF3 in B cell homeostasis, American Association of Immunologists, Miami, FL. 2007 May.

137. Peters A, Gaffney P, Bishop GA. A novel polymorphism in human CD40 enhances B cell activation, Autumn Immunology Conference, Chicago, IL. 2007 November.

138. Munroe ME, Businga TR, Kline JN, Bishop GA. Effects of the anti-inflammatory, natural plant product Honokiol, in a mouse model of asthma, Autumn Immunology Conference, Chicago, IL. 2007 November.

139. VandenBush TJ, Bishop GA. Molecular mechanisms of synergy between CD40 and TLR7, Autumn Immunology Conference, Chicago, IL. 2007 November.



140. Graham J, Moore CR, Bishop GA. Role of the nature of the TRAF binding site in signaling differences between CD40 and its oncogenic viral mimic, LMP1, Autumn Immunology Conference, Chicago, IL. 2007 November.

141. Hildebrand J, Larison K, Mayne C, Hayes C, Bishop GA. TRAF interactions with the BAFF receptor of the mutant A/WySnJ mouse, Autumn Immunology Conference, Chicago, IL. 2007 November.

142. Kraus ZJ, Haring J, Harty JT, Bishop GA. TRAF5 requirement for CD8+ T cell responses to an intracellular pathogen, Autumn Immunology Conference, Chicago, IL. 2007 November.

143. Peters A, Gaffney P, Bishop GA. A novel polymorphism in human CD40 enhances B cell activation, American Association of Immunologists, San Diego, CA. 2008 April.

144. Kraus ZJ, Haring J, Harty JT, Bishop GA. Defects in CD8+ T cell expansion, memory, and response to infection in mice lacking TRAF5, American Association of Immunologists, San Diego, CA. 2008 April.

Selected for Oral Presentation and Travel Award

145. Hildebrand J, Larison KD, Maynes C, Hayes C, Bishop GA. Mature B cell deficiency in the A/WySnJ mouse is associated with altered BAFFR-TRAF interactions, American Association of Immunologists, San Diego, CA. 2008 April.


146. Xie P, Brown LC, Stunz LL, Bishop GA. TRAF3 inhibits signaling by TLRs in B lymphocytes, American Association of Immunologists, San Diego, CA. 2008 April.


147. Poovassery J, VandenBush T, Bishop GA. Antigen receptor signals rescue B cells from TLR tolerance, Autumn Immunology Conference, Chicago, IL. 2008 November.

148. Peters A, Bishop GA. LMP1 accelerates autoimmunity in B6.Sle1 mice, Autumn Immunology Conference, Chicago, IL. 2008 November.

149. Hildebrand J, Mayne C, Hayes C, Bishop GA. Mature B cell deficiency in the A/WySnJ mouse is associated with altered TRAF interactions with BAFFR, Autumn Immunology Conference, Chicago, IL. 2008 November.

150. Arcipowski K, Stunz L, Hostager B, Bishop GA. Molecular mechanisms of TRAF6 activation by CD40 and its oncogenic viral mimic, LMP1, Autumn Immunology Conference, Chicago, IL. 2008 November.



151. VandenBush T, Bishop GA. Optimizing B lymphocyte stimulation for use as cellular vaccines, Autumn Immunology Conference, Chicago, IL. 2008 November.

152. Munroe M, Bishop GA. Potential anti-inflammatory role for E. Angustifolia in a mouse model of inflammatory arthritis, Autumn Immunology Conference, Chicago, IL. 2008 November.

153. Graham J, Bishop GA. The TRAF2/3 binding site in LMP1 and CD40 signaling, Autumn Immunology Conference, Chicago, IL. 2008 November.

154. Kraus Z, Bishop GA. TRAF5 is a positive regulator of LMP1 signaling in vivo, Autumn Immunology Conference, Chicago, IL. 2008 November.

155. Poovassery J, VandenBush TJ, Bishop GA. TLR7 tolerance in B cells: prevention and rescue by antigen receptor signals, American Association of Immunologists, Seattle, WA. 2009 March.

156. Munroe ME, Bishop GA. Abrogation of established inflammatory arthritis by the GABA-A agonist Honokiol, American Association of Immunologists, Seattle, WA. 2009 May.


157. Stunz LL, Bishop GA. Interactions between LMP1 and CD40 signals, American Association of Immunologists, Seattle, WA. 2009 May.

158. Graham J, Moore C, Bishop GA. The role of the TRAF2/3 binding site in LMP1 and CD40 signaling, American Association of Immunologists, Seattle, WA. 2009 May.


159. Munroe ME, Bishop GA. Abrogation of established inflammatory arthritis by the GABA-A agonist Honokiol, Autumn Immunology Conference, Chicago, IL. 2009 November.

160. Decker DA, Bishop GA. Characterization of the role of indirect TRAF6 association in CD40 signaling, Autumn Immunology Conference, Chicago, IL. 2009 November.

161. Arcipowski K, Stunz L, Bishop GA. Molecular mechanisms of TRAF6 utilization by the oncogenic viral mimic of CD40, LMP1, Autumn Immunology Conference, Chicago, IL. 2009 November.

162. Buchta CM, Vanden Bush TJ, Bishop GA. Optimizing the source of APC in cellular vaccines, Autumn Immunology Conference, Chicago, IL. 2009 November.

163. Peters A, Bishop GA. Role of TRAF3 in enhanced signaling by a polymorphism of human CD40, hCD40P227A, Autumn Immunology Conference, Chicago, IL. 2009 November.



164. Graham JP, Bishop GA. The role of TRAF degradation in CD40 versus LMP1 signaling, Autumn Immunology Conference, Chicago, IL. 2009 November.

165. Hildebrand J, Bishop GA. TRAF6, a new member of the proximal signaling complex recruited by BAFFR and TACI in B lymphocytes, Autumn Immunology Conference, Chicago, IL. 2009 November.

166. Decker DA, Bishop GA. Characterization of the role of indirect TRAF6 association in CD40 signaling, American Association of Immunologists, Baltimore, MD. 2010 May.


167. Graham JP, Bishop GA. Role of receptor-mediated TRAF degradation in lymphocyte activation, American Association of Immunologists, Baltimore, MD. 2010 May.


168. Hildebrand J, Bishop GA. TRAF6, a new member of the proximal signaling complex recruited by BAFFR and TACI in B lymphocytes, American Association of Immunologists, Baltimore, MD. 2010 May.


169. Munroe M, Cherascu B, Field E, James J, Bishop GA. Inhibition of inflammation in PBMCs from RA patients by the GABA-A ligand Honokiol, Autumn Immunology Conference, Chicago, IL. 2010 November.

170. Arcipowski K, Stunz L, Graham J, Kraus Z, Vanden Bush T, Bishop GA. Molecular mechanisms of TRAF6 utilization by the oncogenic viral mimic of CD40, LMP1, Autumn Immunology Conference, Chicago, IL. 2010 November.

171. Arcipowski K, Stunz L, Graham J, Kraus Z, Vanden Bush T, Bishop GA. Molecular mechanisms of TRAF6 utilization by the oncogenic viral mimic of CD40, LMP1, 6th Biennial All-Iowa Virology Symposium. 2010 November.


172. Vanden Bush T, Bishop GA. Regulation of cytokine production by CDK4 in antigen presenting cells, Autumn Immunology Conference, Chicago, IL. 2010 November.

173. Buchta C, Stunz L, Vanden Bush T, Bishop GA. Role of TRAF5 in TLR signaling, Autumn Immunology Conference, Chicago, IL. 2010 November.

174. Lin W, Bishop GA. TRAF3 and TRAF6 interaction in the cytoplasm of resting or activated B cells, Autumn Immunology Conference, Chicago, IL. 2010 November.

175. Ontiveros E, Halwani A, Stunz L, Janz S, Bishop GA. A new mouse model of cooperation between MYC and LMP1 in B cell lymphoma development, Keystone Symposium on Normal and Abnormal B Cells, Whistler, Alberta, Canada. 2011 April.



176. Arcipowski K, Bishop GA. The roles of TRAF6 and TAK1 in LMP1-mediated B cell functions, Keystone Symposium on Normal and Abnormal B Cells, Whistler, Alberta, Canada. 2011 April.

177. Decker DA, Bishop GA. Characterization of the indirect role of TRAF6 in CD40 signaling, 13th International TNF Conference, Awaji, Japan. 2011 May.

178. Arcipowski K, Stunz LL, Poovassery J, Bishop GA. Multiple functions for TRAFs in immune regulation, 13th International TNF Conference, Awaji, Japan. 2011 May.

Invited Plenary Session Talk. Ms. Arcipowski was allowed by the organizers to present the invited talk for Dr. Bishop, who as Vice-President elect of the AAI, was required to attend the AAI meeting, held at the same time.

179. Yi Z, Stunz LL, Bishop GA. Roles of TRAF3 in TCR signaling, American Association of Immunologists, San Francisco, CA. 2011 May.


180. Poovassery J, Bishop GA. Type I IFN-mediated reversal of TLR tolerance in antigen presenting cells, American Association of Immunologists, San Francisco, CA. 2011 May.

181. Lin W, Halwani A, Bishop GA. Effects of a multiple myeloma-associated TRAF3 mutation on B cell signaling pathways, Autumn Immunology Conference, Chicago, IL. 2011 November.

182. Vanden Bush T, Bishop GA. Exploiting pre-existing humoral responses to enhance immune responses to new antigens, Autumn Immunology Conference, Chicago, IL. 2011 November.

183. Yi Z, Stunz LL, Bishop GA. Intrinsic effects of TRAF3 on iNKT cell development and function, Autumn Immunology Conference, Chicago, IL. 2011 November.

184. Buchta C, Bishop GA. Roles of TRAF5 in TLR signaling, Autumn Immunology Conference, Chicago, IL. 2011 November.

Selected for AAI Abstract Award, inaugurated at this meeting

185. Buchta CM, Bishop GA. Roles of TRAF5 in TLR signaling, American Association of Immunologists, Boston, MA. 2012 May.


186. Lin W, Hildebrand JM, Bishop GA. The complex relationship between TRAF3 and B cell function, American Association of Immunologists, Boston, MA. 2012 May.


187. Lin W, Hildebrand JM, Bishop GA. The complex relationship between TRAF3 and B cell functions, Autumn Immunology Conference, Chicago, IL. 2012 November.



188. Buchta CM, Bishop GA. TRAF5 negatively regulates TLR signaling, Autumn Immunology Conference, Chicago, IL. 2012 November.

189. Munroe M, Anderson J, Gross T, Stunz L, Bishop GA, James J. EBV CD40 functional mimic LMP1 drives cellular molecular mimicry in the presence of EBNA-1 in a novel murine model of lupus-like disease, American Association of Immunologists, Honolulu, HI. 2013 May.


190. Stunz L, LeBeau R, Bishop GA. LMP1 signaling in vivo downregulates DUSP1 and exacerbates inflammatory responses, American Association of Immunologists, Honolulu, HI. 2013 May.

191. Lin W, Stunz L, LeBeau R, Mambetsariev N, Bishop GA. The role of TRAF3 in B cell-specific regulation of survival and malignancy, American Association of Immunologists, Honolulu, HI. 2013 May.


192. Yi Z, Lin W, Stunz L, Bishop GA. TRAF3 restrains regulatory T cell development by modulating the IL-2 signaling pathway, American Association of Immunologists, Honolulu, HI. 2013 May.

193. Buchta CM, Bishop GA. TRAF5 negatively regulates TLR signaling, American Association of Immunologists, Honolulu, HI. 2013 May.


194. Wallis AM, Yi Z, Bishop GA. TRAF3 regulates CSK to enhance TCR signaling, Autumn Immunology Conference, Chicago, IL. 2013 November.

195. Mambetsariev N, Stunz LL, Lin WW, Bishop GA. TRAF3- a novel regulator of CREB transcription factor in B cells, Autumn Immunology Conference, Chicago, IL. 2013 November.

196. Buchta CM, Bishop GA. TRAF5 negatively regulates TLR signaling via inhibition of TAB function in B cells, Autumn Immunology Conference, Chicago, IL. 2013 November.

B. Areas of Research Interest

B cell malignancies.

B cell signaling and transformation by Epstein-Barr virus.

Immune cell signaling by TNFR superfamily receptors and TRAF molecules.

Interactions between innate and adaptive immunity.

Novel cellular vaccine technology employing B lymphocytes.

Role of CD40 in diet-induced obesity and insulin resistance.



C. Grants

Grant Completed

Regulation of Lymphocyte Receptor Signaling by TRAF Interactions

US Department of Health & Human Services, National Institutes of Health

R01 AI049993

$2,335,380.00 Direct, $1,107,911.00 Indirect

September 1, 2001 - June 30, 2012

Percent effort: 15

Bishop, Gail A (Principal)

Modulation of Acute Lung Injury


R01 HL077431

$981,170.00 Direct, $466,055.00 Indirect

September 15, 2004 - June 30, 2009

Percent effort: 5

Hunninghake, Gary (Principal)

Molecular Mechanisms of Lymphocyte Activation in Immunity, Autoimmunity and Malignancy

Roy J. Carver Charitable Trust

$400,000.00 Direct, $0.00 Indirect

May 1, 2007 - April 30, 2012

Percent effort: 0


Characterization of Echinacea as an Immunomodulator in Autoimmune Inflammatory Diesase


430-28-14

$538,012.00 Direct, $251,281.00 Indirect

June 1, 2007 - May 31, 2011

Percent effort: 2.5



Diane Birt (Principal)

Anti-Inflammatory Actions of the Natural Plant Product, Honokiol


R21 AT003998

$275,000.00 Direct, $137,500.00 Indirect

August 1, 2008 - January 31, 2011

Percent effort: 10


Carver Research Program of Excellence (RPOE)

Roy J. Carver Charitable Trust

$600,000.00 Direct, $0.00 Indirect

May 1, 2009 - March 31, 2012

Percent effort: 0


Improving Vaccine Immunogenicity by Exploiting Pre-Existing Humoral Responses


WU-10-99

$528,572.00 Direct, $264,286.00 Indirect

September 12, 2009 - August 31, 2012

Percent effort: 5


Understanding the Mechanism of Action of the Therapeutic CD40-Specific Antagonistic mAb PG102

PanGenetics B.V.

$39,350.00 Direct, $19,675.00 Indirect

September 16, 2009 - September 15, 2010

Percent effort: 2.5


Funded



Interactions between innate and adaptive immune receptors on B lymphocytes

US Department of Veterans Affairs

VA Merit Review 383

April 1, 1990 - September 30, 2016


The Roles of TRAF3 in Lymphocyte Signaling


R01 AI028847

$3,500,602.00 Direct, $1,639,617.00 Indirect

September 1, 1990 – June 30, 2015

Percent effort: 15


Mechanisms of Alteration of B Lymphocyte Function by LMP1


R01 CA099997

$2,260,583.00 Direct, $1,096,127.00 Indirect

March 7, 2003 - February 28, 2015

Percent effort: 20


Senior Research Scientist Career Award

US Department of Veterans Affairs

October 1, 2003 - September 30, 2020


Currently Under Review

TRAF3 promotes TCR-CD28 signaling


R21 AI114698

$275,000.00 Direct, $140,250.00 Indirect

October 1, 2014 – September 30, 2016



Percent effort: 7


PPG Funded

Cancer Center Support Grant (CCSG)


P30 CA086862

$23,821,886.00 Direct, $11,497,243.00 Indirect

July 14, 2000 - March 31, 2016

Percent effort: 10

Weiner, George J (Principal)

Lymphoma Specialized Program of Research Excellence (SPORE)


P50 CA097274

$29,484,215.00 Direct, $4,816,157.00 Indirect

September 11, 2002 - June 30, 2017

Percent effort: 5

No Principal Investigator

Training Grant Funded

Predoctoral Training Program in Immunology


T32 AI007485

$3,096,944.00 Direct, $203,463.00 Indirect

August 1, 1995 - July 31, 2015

Percent effort: 0


D. Presentations



Invited Lectures/Guest Speaker

2000 Annual Meeting, American Academy of Allergy, Asthma, and Immunology, San Diego, CA. Structure and function of the MHC

2007 Annual Meeting, American Association of Immunologists, Miami, FL. Paddling your own canoe - negotiating a rewarding path as an independent scientist

2007 Lecture for Introductory Immunology Course, American Association of Immunologists, Philadelphia, PA. Made for each other: T-B cell collaboration in the immune response

2009 Annual Meeting, American Association of Immunologists, Seattle, WA. Helping your grant rise to the top of the study section

2011 Annual Meeting, American Association of Immunologists, San Francisco, CA. Making your voice heard on Capitol Hill

Conference Presentations/Seminars

1982 6th Annual Herpesvirus Symposium, Cold Spring Harbor Laboratory, Cold Spring, NY. Characteristics of human natural killer activity against target cells infected with Herpes simplex virus type 1

1983 University of North Carolina, Chapel Hill, NC. Characterization of Human Natural Killer Activity Against Herpes Simplex-Infected Targets

1983 Annual Meeting, American Society for Virology. Recognition by natural killer cells of viral glycoproteins on target cells infected with HSV-1

1984 American Association of Immunologists, St. Louis, MO. Analysis of the specificity of natural killer cells for HSV-1 infected targets

1985 10th International Herpesvirus Symposium, Ann Arbor, MI. Clonal specificity of human natural killer cells for determinants of HSV-1 glycoproteins

1986 American Association of Immunologists, St. Louis, MO. Induced differentiation of a B cell clone: role of surface immunoglobulin, class II antigen and IL-2 receptor

1988 Indiana University, Indianapolis, IN. The Class II Molecule as a Signal Transducer to the B Cell

1988 SUNY, Stony Brook, NY. The Class II Molecule as a Signal Transducer to the B Cell

1988 University of California, Davis, CA. The Class II Molecule as a Signal Transducer to the B Cell

1988 University of Utah, Salt Lake City, UT. The Class II Molecule as a Signal Transducer to the B Cell

1988 Glaxo, Inc., Research Triangle Park, NC. The Class II Molecule as a Signal Transducer to the B Cell

1988 University of Iowa, Iowa City, IA. The Class II Molecule as a Signal Transducer to the B Cell

1988 University of Colorado, Denver, CO. The Class II Molecule as a Signal Transducer to the B Cell



1988 Mayo Clinic, Rochester, MN. The Class II Molecule as a Signal Transducer to the B Cell

1988 University of Minnesota, Minneapolis, MN. The Class II Molecule as a Signal Transducer to the B Cell

1989 Uniformed Services University of the Health Sciences, Bethesda, MD. The Class II Molecule as a Signal Transducer to the B Cell

1989 Department of Internal Medicine, University of Iowa, Iowa City, IA. The Class II Molecule as a Signal Transducer to the B Cell

1989 18th Annual Autumn Immunology Conference. Haplotype-specific differences in signaling by transfected class II molecules to a B cell clone

1990 Oxford University, Oxford, UK. Class II and Ig Molecules in B Cell Signaling

1991 CD5 B Cells in Development and Disease, New York Academy of Sciences Conference, Miami, FL. Ig and class II-mediated signaling in CD5 B cells

1992 8th International H-2/HLA Workshop, Jekyl Island, GA. Effects of structural alterations of the MHC class II beta chain on class II-mediated B cell activation

1993 Program in Molecular Biology, University of Iowa, Iowa City, IA. Molecular Characterization of Ig and MHC Class II Molecules as B Cell Signal Receptors

1994 University of North Carolina, Chapel Hill, NC. Molecular Mechanisms in Ig and Class II-Mediated B Cell Signaling

1994 9th International H-2/HLA Workshop, Garda, Italy. Length and sequence requirements of the cytoplasmic domain of the Aβ molecule for class II-mediated B cell signaling

1994 Immunology Program, University of Iowa, Iowa City, IA. Regulation of B Cell Activation by mIg, MHC Class II, and CD40 Signals

1994 University of Virginia, Charlottesville, VA. A Structure-Function Analysis of Class II as a B Cell Signal Receptor

1995 Microbiology, University of Iowa, Iowa City, IA. Molecular Mechanisms of B Cell Signaling by MHC Class II and CD40

1996 University of Michigan, Ann Arbor, MI. Signaling to B Cells via MHC Class II and CD40

1996 Infectious Diseases Research Seminars, University of Iowa, Iowa City, IA. Signaling to B Cells via MHC Class II and CD40

1996 American Association of Immunologists, New Orleans, LA. Distinct CD40 structural requirements regulate CD40-mediated signals

1996 Autumn Immunology Conference, Chicago, IL. Regulation of CD40 Signaling Pathways

1997 3M Pharmaceuticals, St Paul, MN. Molecular Characterization of CD40 Signaling to B Cells

1997 National Jewish Hospital & University of Colorado Health Sciences Center, Denver, CO. CD40 Signaling: Using Structural Clues to Solve Functional Mysteries

1997 University of Indiana Medical School, Indianapolis, IN. Signaling to B Cells by



CD40 and LMP1

1998 Iowa State University, Ames, IA. Roles of NF-κB and TRAFs in CD40 Signaling to B Cells

1999 Biochemistry Research Workshop, University of Iowa, Iowa City, IA. TRAFs and Rafts in CD40 Signaling

1999 3M Pharmaceuticals, St Paul, MN. Molecular Mechanisms of R848 Signaling to B Cells

2000 University of Toronto, Toronto, Canada. Signaling by CD40 and the Oncogenic Protein LMP1 - Roles of TRAFs and Rafts

2000 University of Alabama, Birmingham, AL. Molecular mechanisms of CD40 signaling

2000 Ohio State University and Children's Hospital Research Center, Columbus, OH. TRAFs and rafts in CD40 and LMP1 signaling

2000 8th International Congress on TNF and Related Molecules, Trondheim, Norway. Roles of TRAFs and rafts in B Cell Signaling by CD40 and the Oncoprotein LMP1

2000 Trudeau Institute, Saranac Lake, NY. TRAFs and rafts in CD40 and LMP1 signaling

2000 UNC-Lineberger Cancer Center 25th Annual Postdoctoral-Faculty Research Conference, Chapel Hill, NC. TRAFs and rafts in signaling to B lymphocytes by CD40 and its oncogenic mimic, LMP1

2001 Penn State University, State College, PA. B cell signaling by CD40 and the oncoprotein LMP1: Roles of TRAFs and rafts

2001 Oklahoma Medical Research Foundation, Oklahoma City, OK. Differential TRAF regulation and signaling to B cells by CD40 and the oncogenic protein LMP1

2001 MD Anderson Cancer Center, Houston, TX. TRAFs and rafts in differential signaling to B cells by CD40 and the EBV oncoprotein, LMP1

2001 Cytokine Odyssey 2001, Maui, Hawaii. TRAFs and rafts in B lymphocyte signaling

2001 First Annual Buffalo Conference on Immunology, SUNY-Buffalo, NY. TRAFs and rafts in B lymphocyte signaling

2002 University of Michigan, Ann Arbor, MI. The many faces of TRAFs in B cell signaling

2002 Duke University, Durham, NC. Regulation of TRAFs in signaling to B cells by CD40 and LMP1

2002 University of Miami, Coral Gables, FL. Regulation of TRAFs in signaling to B cells by CD40 and its oncogenic mimic, LMP1

2002 University of Illinois, Chicago, IL. Regulation of TRAFs in B lymphocyte signaling

2002 Roswell Park Cancer Institute, Buffalo, NY. Roles of TRAF molecules in signaling by CD40 and its oncogenic mimic, LMP1

2002 TNF Superfamily Conference, San Diego, CA. Molecular characterization of



signaling differences between CD40 and LMP1

2002 University of Pennsylvania, Philadelphia, PA. New insights into the roles of TRAF molecules in B lymphocyte signaling

2003 Cleveland Clinic, Cleveland, OH. The roles played by TRAF molecules in signaling by CD40 and its oncogenic mimic, LMP1

2003 Mt Sinai Medical Center, New York, NY. Multiple roles for TRAFs in signaling to B lymphocytes by TNFR family molecules

2004 Midwinter Conference of Immunologists, Asilomar, Pacific Grove, CA. New insights into TRAF functions in lymphocyte activation

2004 Gordon Research Conference on Immunochemistry & Immunobiology, Santa Barbara, CA. TRAF regulation by B lymphocytes

2004 Rutgers University School of Medicine, New Brunswick, NJ. New insights into TRAF functions in B lymphocytes

2004 Albany Medical College, Albany, NY. New insights into TRAF functions in B lymphocytes

2004 NIH, Bethesda, MD. New approaches to understanding lymphocyte TRAF functions

2004 University of Louisville, Louisville, KY. New insights into TRAF functions in B lymphocytes

2004 Stanford University, Stanford, CA. New insights into TRAF functions in B lymphocytes

2005 University of Alabama, Birmingham, AL. TRAFs wear many hats in B lymphocyte activation

2005 University of California-San Diego, La Jolla, CA. Signaling to B cells by CD40 and its evil twin, LMP1

2005 University of Minnesota, Minneapolis, MN. Signaling to B cells by CD40 and its evil twin, LMP1

2005 Summer Conference on Signal Transduction in the Immune System, FASEB, Snowmass, CO. TRAF function in lymphocyte signaling

2005 University of California, San Francisco, CA. CD40 and its evil twin in B lymphocyte activation

2006 University of South Florida, Tampa, FL. Uncovering the secret life of TRAF3: Roles in regulating B cell activation

2006 University of Wisconsin, Madison, WI. Multiple roles of TRAFs in lymphocyte activation

2006 National Institutes of Health, Bethesda, MD. Multiple roles for TRAF3 in lymphocyte activation

2007 TNFR Superfamily Conference, Asilomar, Pacific Grove, CA. Understanding the many faces of TRAF3

2008 University of Massachusetts, Worcester, MA. The multiple personalities of TRAF molecules

2008 Case Western Reserve University, Cleveland, OH. The many roles of TRAF3 in lymphocyte function



2008 Conference on Immunology, Cancer, & Infectious Disease, NIH, Bethesda, MD. Multiple roles played by TRAF3 in lymphocyte activation and regulation

2008 University of Toronto, Toronto, Canada. Multiple roles for TRAF3 and TRAF5 in lymphocyte activation

2008 New York University, New York, NY. Multiple roles for TRAF3 and TRAF5 in lymphocyte activation

2009 5th Leukocyte Signal Transduction Conference, Aegean Conferences, Crete. The many roles of TRAFs in lymphocyte function

2009 Indiana University, Indianapolis, IN. Multiple roles for TRAF3 and TRAF5 in lymphocyte activation

2009 The Burnham Institute for Medical Research, La Jolla, CA. Multiple roles for TRAF3 and TRAF5 in lymphocyte activation

2009 Department of Microbiology & Immunology, University of North Carolina, Chapel Hill, NC. TRAFs and TLRs in lymphocyte activation and vaccination

2009 Graduate Program in Immunology, University of Iowa, Iowa City, IA. TRAFs and TLRs in lymphocyte activation and vaccination

2009 Department of Pharmacology, University of Iowa, Iowa City, IA. The Many Faces of TRAFs

2010 University of North Carolina Cancer Center, Chapel Hill, NC. The many faces of TRAF molecules in immune function and regulation

2010 Vanderbilt University, Nashville, TN. TRAFs and TLRs in lymphocyte activation and vaccination

2010 Immunology Retreat, NIH, Cambridge, MD. Multiple personalities for TRAF3 in lymphocyte regulation

2011 La Jolla Institute for Allergy & Immunology, La Jolla, CA. Multiple personalities for TRAFs in immune regulation

2011 Annual European Congress of Rheumatology, London, UK. Mouse models for the role of EBV in autoimmunity

2011 6th International Leukocyte Signal Transduction Workshop, Crete, Greece. Multiple roles for TRAF molecules in immune cell regulation

2011 University of Wisconsin, Madison, WI. Roles of distinct TRAF usage in normal vs. abnormal receptor function

2011 40th Autumn Immunology Conference, Chicago, IL. The multifaceted roles of TRAF molecules in immune cell regulation.

2012 Case Western Reserve University, Cleveland, OH. Multiple personalities for TRAFs in immune regulation

2012 Blood Research Institute, Milwaukee, WI. Multiple personalities for TRAFs in immune regulation

2012 MD Anderson Cancer Center, Houston, TX. Roles of TRAFs in the regulation of B cell function and malignancy

2012 National Jewish Hospital & University of Colorado Integrated Immunology Program, Denver, CO. Multiple personalities for TRAF3 in B vs. T lymphocytes



2012 New York Immunology Conference, Lake George, NY. Multiple personalities for TRAF molecules in immune regulation

2013 University of Missouri, Columbia, MO. Multifaceted roles for TRAFs in immune regulation

2013

2013

2013

2013

2014

American Association of Immunologists, Honolulu, HI. The many faces of TRAF molecules in immune regulation

14th International TNF Conference, Quebec City, Quebec. The Multifaceted roles of TRAF molecules in immune regulation.

University of Connecticut Health Science Ctr., Farmington, CT. New roles for TRAF3 and CD40 in T lymphocytes.

Plenary speaker, UC-Irvine Immunology Fair. Multifaceted roles of TRAF molecules in immune regulation.

U. of Oklahoma School of Medicine, Oklahoma City, OK. New roles for TRAF3 and CD40 in T lymphocytes. Murphy Distinguished Lecture.

IV. SERVICE

A. Memberships, Services, and Committees Memberships in Professional Organizations

1984 - Present American Association of Immunologists

1986 - Present American Association for the Advancement of Science

1986 - Present American Society for Microbiology

2001 - Present American Association for Cancer Research, Member

2002 - Present American Society for Biochemistry & Molecular Biology, Member

2006 - Present Society for Leukocyte Biology, Member

Offices Held in Professional Organizations

2011 - 2012 American Association of Immunologists, Vice President

2012 - 2013 American Association of Immunologists, President

2013 - 2014 American Association of Immunologists, Past President

Editorships

1994 - 1998 The Journal of Immunology, Associate Editor

1998 - 2002 The Journal of Immunology, Section Editor

2006 - Present The Journal for Leukocyte Biology, Editorial Board Member

Review Panels

1989 - Present American Journal of Pathology, Ad Hoc Reviewer



1989 - Present American Journal of Physiology, Ad Hoc Reviewer

1989 - Present Biotechniques, Ad Hoc Reviewer

1989 - Present Cancer Research, Ad Hoc Reviewer

1989 - Present Cellular Immunology, Ad Hoc Reviewer

1989 - Present Clinical and Experimental Immunology, Ad Hoc Reviewer

1989 - Present European Journal of Immunology, Ad Hoc Reviewer

1989 - Present Immunity, Ad Hoc Reviewer

1989 - Present Immunology Letters, Ad Hoc Reviewer

1989 - Present International Immunology, Ad Hoc Reviewer

1989 - Present Journal of Biological Chemistry, Ad Hoc Reviewer

1989 - Present Journal of Experimental Medicine, Ad Hoc Reviewer

1989 - Present Journal of Virology, Ad Hoc Reviewer

1989 - Present Nature Immunology, Ad Hoc Reviewer

1989 - Present PNAS, Reviewer, Ad Hoc Reviewer

1989 - Present Transplantation, Ad Hoc Reviewer

1989 - Present U.S. VA Research Grants, Ad Hoc Reviewer

1989 - Present Virology, Ad Hoc Reviewer

1992 NIH Study Section on International and Cooperative Projects (ICP), Ad Hoc Reviewer

1993 - Present Research grants of the Swiss Medical Research Foundation, Ad Hoc Reviewer

1993 National Science Foundation Grants, Cell Biology section, Ad Hoc Reviewer

1994 - 1997 Immunology/Microbiology Study Section, American Heart Association, Member

1996 - 1998 Panel on Signal Transduction and Regulation (Cell Biology), NSF, Member

1996 NIH Study Section on International and Cooperative Projects (ICP), Ad Hoc Member

1997 NIH Experimental Immunology Study Section, Ad Hoc Member

1997 NIH Experimental Immunology Study Section, Ad Hoc Member

1998 - 2002 NIH Experimental Immunology Study Section, Member

2001 - Present Research Grants, Israel Academy of Sciences & Humanities, Ad Hoc Reviewer

2003 NIAID Study Section on Pre-and Postdoctoral Training Grants in Immunology & Infectious Disease, Ad Hoc Member

2003 NIH ALY Study Section, Ad Hoc Member

2004 Special Emphasis Panel, NIH, Member

2005 - 2007 NIH U19 Review Panel, Oklahoma Medical Research Foundation, Chair




2006 Immunology Grant Review Panel (6-member international panel), Singapore Government, Member

2007 - Present NIH Tolerance, Tumors, & Transplantation Study Section, Member

2007 Special Emphasis Panel, NIH, Committee Chair

2008 - 2010 NIH Tolerance, Tumors, & Transplantation Study Section, Chair

2009 - Present NIH U19 Review Panel, Oklahoma Medical Research Foundation, Chair

2009 - Present Self/Non-self, Editorial Review Board Member


2011 Special Emphasis Panel, NIH, Chair





2013

2013

2014

2014

2014

Veterans Administration Review Panel for RCS Awards, Member

Special Emphasis Panel, NIH, Member

Veterans Administration Review Panel for RCS Awards, Member

NIAID AITC (T32 and K awards) study section, ad hoc member

NCI special panel to formulate “provocative questions” in cancer.

Departmental, Collegiate, University and National Committees

1990 - Present Flow Cytometry Advisory Committee, College of Medicine, Member

1990 College of Medicine Research Committee, Reviewer, Ad Hoc Reviewer

1991 - 1993 College of Medicine Research Committee, Member

1991 - 1993 Immunology Group Executive Committee, Member

1992 - 1998 Comprehensive Cancer Center Scientific Advisory Committee, Member

1992 - 1993 College of Medicine Executive Committee, Member

1993 - 1994 College of Medicine Executive Committee, Secretary

1994 - 1995 College of Medicine Executive Committee, Vice-Chair

1995 Planning Council, Iowa HHMI Research Program Grant, Member

1996 - 1998 Research Advisory Committee, Biological Sciences, Office of the VP for Research, Committee Member

1997 College of Medicine Self-Study Committee, Member

1998 COM Research Retreat, Focus Committee on Faculty Grant Support, Member

1999 - Present Cancer Center Executive Committee, Member

1999 - 2002 Finance Committee, American Association of Immunologists, Member

2002 - 2007 Public Affairs Committee, American Association of Immunologists, Member



2004 VPR Search Committee, Committee Member

2005 - 2008 FASEB Science Policy Committee, AAI Representative

2006 - Present External Research Advisory Committee, U. of South Dakota, Member

2006 - Present FASEB Ad Hoc Subcommittee on NIH Peer Review, Chair

2006 - 2009 Council Delegate (Medical Sciences), AAAS, Member

2007 - 2009 Postdoctoral Fellow Advisory Committee (Graduate College), Committee Member

2009 - Present MRCE Steering Committee, Member

2009 - 2010 Graduate College Task Force on Graduate Education, Member

2011 External Advisory Committee, U. of Michigan Life Sciences Institute, Member

Service Positions

1989 18th Annual Autumn Immunology Conference, Workshop Chair: Signaling Events in Lymphocyte Activation

1990 19th Annual Autumn Immunology Conference, Workshop Chair: Genetic Regulation of the Immune Response

1991 20th Annual Autumn Immunology Conference, Workshop Chair: Immunogenetics and Molecular Immunology

1993 - 1997 Governing Board of Autumn Immunology Conference, Member

1993 22nd Annual Autumn Immunology Conference, Workshop Chair: Lymphocyte Activation and Development

1994 Autumn Immunology Conference, Workshop Coordinator

1995 Autumn Immunology Conference, Secretary

1996 25th Annual Autumn Immunology Conference, Plenary Session Chair: Roles of TNF-R Family Molecules in the Immune System

1996 Autumn Immunology Conference, Chair

1999 - 2002 Cellular Activation in Cancer Program, Holden Cancer Ctr., Director

1999 American Association of Immunologists Annual Meeting, Symposium Chair: B Lymphocyte Activation

2001 - Present Signal Transduction - Receptors, Mediators and Genes, Advisory Board

2001 American Association of Immunologists Annual Meeting, Symposium Chair: Signal Transduction and Lymphocyte Activation

2002 - Present Program in Immunology & Immunotherapy of Cancer, Holden Cancer Center, Co-Director

2002 TNF Superfamily Conference, Workshop Chair: selected oral presentations from posters, Molecular characterization of signaling differences between CD40 and LMP1

2003 American Association of Immunologists Annual Meeting, Symposium Chair: Lymphocyte Activation

2004 - Present Basic Science Research, Holden Cancer Center, Associate Director



2004 American Association of Immunologists Annual Meeting, Symposium Chair: Regulation of Signaling Pathways in Immune Cells

2007 - 2011 Governing Council of the American Association of Immunologists, Member

2008 37th Annual Autumn Immunology Conference, Workshop Chair: B Cell Activation

2008 American Association of Immunologists Annual Meeting, Symposium Chair: Regulation of B cell responses

2009 38th Annual Autumn Immunology Conference, Workshop Chair: B Cell Activation and Signaling

2009 NIAID Board of Scientific Counselors, Ad Hoc Member

2010 - Present Scientific Advisory Board, Blood Center of Wisconsin, Member

2010 39th Annual Autumn Immunology Conference, Workshop Chair: B Cell Activation and Signaling

2010 American Association of Immunologists Annual Meeting, Symposium Chair: B cell activation and regulation

2011 6th International Leukocyte Signaling Workshop, Plenary Session Chair: Intracellular signaling and regulation

2012 American Association of Immunologists Annual Meeting, Symposium Chair: Innate Immune Receptor Signaling

2013 American Association of Immunologists, President's Symposium

B. Clinical assignments since last promotion (if applicable)

i. educational and professional history · i. educational and professional history a. list of...

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