ifba’s biocontainment engineering network istanbul. july, 2011 k. ugwu co-chair ifba...
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IFBA’s Biocontainment Engineering Network
Istanbul. July, 2011K. UgwuCo-chair
IFBA Biocontainment Engineering Working Group
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• International non-profit NGO• Working around the world since 2001 to address biological threats and advance biosafety/biosecurity • Advocacy and operational Role
Promoting Biosafety through World-wide Collaboration
International Federation of
Biosafety Associations
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IFBA Members & Observers
• Member associations (Biosafety Associations)• Observer organizations (Multilateral organizations, governments, NGOs, Academia)
• Griffin Foundation, US BEP, ICLS, GPP, CDC, Redi Centre, Sandia...
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IFBA – Building Biocontainment Capacity
Promoting Biosafety through World-wide Collaboration
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Network of Biocontainment Expertise
Biosafety professionals, scientists, lab technicians, academics, architects, engineers, managers, policy makers, …….
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Understanding Local Context
• Capacity building in resource-limited countries must be practical, sustainable and based on the needs of the country
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IFBA Biosafety Engineering Network
• Identify practical solutions to containment facilities
• Advocacy to include these approaches in international guidelines and best practices
• Mentor those new to the field• Build global capacity• ERG/IFBA/Germfree Sustainable Engineering award
• Build consensus on controversial issues
• Find simple safe and workable solutions for resource establishments Sustainable, practical and local solutions...
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Local, Practical, Sustainable
• Cost pressures• Local unavailability of highly
technical equipmentand replacement parts
• Unreliable utilities and fluctuating power supply
• Unfamiliarity of constructing and operating a highly complex BSL3 facility
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What are we trying to achieve…
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How do we get there?
No “one size fits all” for BSL3 facilities
• apply different approaches and solutions • need careful planning and programming before you start the design process• based on the risk assessment
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Why Risk Assessment is Important
Don’t build this…..
Big money….
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Why Risk Assessment is Important
When all you need is this …..
Pocket change….
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Why Risk Assessment is Important
Do not want to “overdesign” laboratory
• BSL3 containment space is very expensive to build, operate and maintain
• Working at BSL3 is less efficient (protective clothing, entry/exit procedures, medical surveillance)
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Why Risk Assessment is Important
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Risk Assessment/Lab Programming
• Complete your risk assessment with architects and engineers during Lab Programming
• Answers to these questions will drive the design
• what pathogens• what diagnostic tests• what SOPs• how many samples ....
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Building a Biocontainment Lab
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Programming the Lab
• Meet with architects and engineers to identify the scientific program requirements for the lab • Conduct risk assessment together• Design a laboratory that meets both the scientific needs and containment requirements• Define architectural and mechanical concepts for the facility
The most important step in the entire process!!Lead to a successful certification…
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Programming the Lab
• Zoning approach to containment and security
•Architectural/ mechanical is are not over-designed at BSL2 and support spaces
• Balance between electronic and operational solutions
•Using visual signage vs electonic door interlocks
• Simple architectural solutions•Epoxy-based paint on gympsum board for interior BSL3 walls•Monolithic sheet-vinyl flooring in BSL3 lab areas utilities
• Simple mechanical solutions•Using flow-offset to achieve inward directional airflow•Limiting number of Class IIB2 BSCs
Conceptual design decisions for successful certification!!
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International Certification
• No international accredited certification program for biocontainment facilities
• Several national authorities have accredited “certifiers” • Singapore, Canada
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International Certification
• No detailed set of international certification criteria to follow
Detailed certification criteria
General certification criteria
??
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International Certification
• New set of criteria under development in US
• International applicability?
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International Certifiers?
• IFBA Biosafety Professionals Recognition program
• Exploring options for recognizing engineers/architects who design, build, commission and operate biocontainment facilities
• What about certifiers?