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Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller, Hua Jane Lou, Lara Perryman, Thomas R. Cox, Nevena Zivanovic, Antonio Palmeri, Agata Wesolowska-Andersen, Manuela Helmer-Citterich, Jesper Ferkinghoff-Borg, Hiroaki Itamochi, Bernd Bodenmiller, Janine T. Erler, Benjamin E. Turk, Rune Linding Cell Volume 163, Issue 1, Pages 202-217 (September 2015) DOI: 10.1016/j.cell.2015.08.056 Copyright © 2015 The Authors Terms and Conditions

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Page 1: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling 

Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller, Hua Jane Lou, Lara Perryman, Thomas R. Cox, Nevena Zivanovic, Antonio Palmeri, Agata Wesolowska-Andersen, Manuela Helmer-Citterich, Jesper Ferkinghoff-Borg, Hiroaki

Itamochi, Bernd Bodenmiller, Janine T. Erler, Benjamin E. Turk, Rune Linding 

Cell Volume 163, Issue 1, Pages 202-217 (September 2015)

DOI: 10.1016/j.cell.2015.08.056

Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 2: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure 1

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 3: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure 2

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 4: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure 3

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 5: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure 4

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 6: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure 5

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 7: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure 6

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 8: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure 7

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 9: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure S1

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 10: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure S2

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 11: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure S3

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 12: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure S4

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 13: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Figure S5

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions
Page 14: Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling Pau Creixell, Erwin M. Schoof, Craig D. Simpson, James Longden, Chad J. Miller,

Cell 2015 163, 202-217DOI: (10.1016/j.cell.2015.08.056) Copyright © 2015 The Authors Terms and Conditions

http://www.elsevier.com/termsandconditions

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