m. k. müller kantonsspital frauenfeld das... · treatment of secondary peritonitis e.g. after...

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Left open Abdomen & 2nd look on demand? M. K. Müller Kantonsspital Frauenfeld Der chirurgische Bauch- eine interdisziplinäre Herausforderung 9. Nov. 2018

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Page 1: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Left open Abdomen & 2nd look on demand?

M. K. Müller

Kantonsspital Frauenfeld

Der chirurgische Bauch-eine interdisziplinäre Herausforderung 9. Nov. 2018

Page 2: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 3: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 4: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Sekundäre Peritonitis nach:

Page 5: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Outline

Left open abdomenClosed

scheduled 2nd look

Closed2nd look on demand

Verschluss nichtmöglich

DefinitiverVerschluss nicht

gewollt

DefinitiverVerschluss mit

Kriterien

Page 6: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Wieso, weshalb, warum?

• Heterogenes Patientengut– Alter

– Geschlecht

– Begleiterkrankungen

– Exogene Noxen (Nikotin, Medikamente)

• Heterogene Ursache der Peritonitis

• Individuelle Entscheidung

Page 7: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Left open abdomen

Left open abdomen

Verschluss nichtmöglich

• ‘Damage control’

• Kontamination

• Lange Operationszeit

• Kompartment

Page 8: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 9: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

‘Right operation on the right patient

at the right time’

‘Life before Abdominal wall’

Page 10: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Left open abdomen

Left open abdomen

Verschluss nichtmöglich

• ‘Damage control’

• Kontamination

• Lange Operationszeit

• Kompartment

Page 11: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Case male 34 years

• 192 kg, 180 cm, BMI 59.3 kg/m2

• art. Hypertension

• OSAS, Nicotine 15py

Page 12: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Case 2 male 35 years

Lap. Gastric Bypass (100 min), 07.10.2014

a 250 cm, b 100 cm, circular stapler 25 mm

postoperative ICU 24h

until 4. pod good recovery

Page 13: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Case 2 male 35 years

4. pod

Tachycardia, Dyspnoe, CRP 178 mg/l

CT scan

Page 14: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 15: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 16: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 17: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Case 2 male 35 years

12.10.2015

• Resection of incarcerated small bowel, anastomosis 120 cm proximally to ileoceacal valve

• Revision of Entero-Enterostomy

• Revision of Gastro-Enterostomy and Omental patch

• Decompression of remnant stomach

Page 18: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 19: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 20: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Further course

• Operative lavage14.10. / 16.10. / 20.10. / 21.10. / 23.10. / 28.10. / 29.10. / 31.10. / 02.11. / 06.11.

• Revision of Entero-Enterostomy18.10. / 19.10. / 25.10. / 26.10. / 27.10.

• Rectus muscle flap04.11.

Page 21: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Further course

• Lavage, Vicryl Mesh, Vac08.11.

• Lavage and Vac10.11. / 14.11. / 17.11.

• Skin graft24.11.

• Tracheostomy, Antibiotics , TPN, Hemodialysis, ICU 12.10. until 17.12.

Page 22: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 23: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Further course

• Hospital stay 07.10.2014 until 05.01.2015Neurorehabilitation until 09.05.2015

• Outpatient visit 25.02.129 kg, - 57 kg

• Outpatient visit 15.04.120 kg, - 66 kg

• Outpatient visit 16.07.wheelchair and walking sticks

Page 24: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Treatment of secondary peritonitise.g. after bariatric surgery

• Irrigate & drain the abdominal cavity

• Seal the leaks with an endoscopic stent or clips or sutures or all of the above

• Scheduled looks in the OR

• Get ahead of septicaemia

• Don’t bother about the abdominal wall

Page 25: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Open abdomen

Pros

• No compartment

• Better drainage of contamination

Cons

• Fluid loss

• Temperature control

• Abdominal wall retraction

Page 26: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Left open

Page 27: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Technische Möglichkeiten

• Abdominaler Vac

• Sucutaner Vac

• Retraktionssysteme (z.B: Abra System)

• Ventrofil

• Bogota Bag

• Meshes

• etc.

Page 28: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 29: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Left open

Page 30: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 31: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 32: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 33: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 34: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

The highest weighted fascial closure rate was found in series describing NPWT with continuous mesh or suture mediated fascial traction was 73.1 %.

Weighted rates of fistula varied from 5.7 % after NPWT with fascial traction and 17.2 % after mesh inlay .

Although the best results in terms of achieving delayed fascial closure and risk of enteroatmospheric fistula were shown for NPWT with continuous fascial traction, the overall quality of the available evidence was poor, and uniform recommendations cannot be made.

Page 35: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Outline

Left open abdomenClosed

scheduled 2nd look

Closed2nd look on demand

Verschluss nichtmöglich

DefinitiverVerschluss nicht

gewollt

DefinitiverVerschluss mit

Kriterien

Page 36: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Outline

Closedscheduled 2nd look

DefinitiverVerschluss nicht

gewollt

Page 37: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Temporary Closure, 2nd look

Indication

• Contamination

• Critical ischemia

Risk

• Overtreatment

• Damage to the abdominal wall

Page 38: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 39: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Outline

Left open abdomenClosed

scheduled 2nd look

Closed2nd look on demand

Verschluss nichtmöglich

DefinitiverVerschluss nicht

gewollt

DefinitiverVerschluss mit

Kriterien

Page 40: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Outline

Closed2nd look on demand

DefinitiverVerschluss mit

Kriterien

Kriterien für die Relaparotomie

Page 41: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Second look on demand

Comparison of On-Demand vs Planned Relaparotomy Strategy in Patients With Severe Peritonitis

A Randomized Trial

Multicenter n=5, Netherlands, 2001-2005

116 on demand vs. 116 planned

10 Endpoint: 12 mth mortality

O van Ruler , JAMA 2007

Page 42: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Inclusion criteria

• Secondary peritonitis requiring emergency laparotomy

– Perforation or infection of visceral organ

– Ischemia due to strangulation

– Postoperative peritoneal infection

• APACHE II Score >10

Page 43: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Randomization

Planned

• Every 36-48h

• The sequence was terminated, when macroscopically clean

On-demand

• Clinical deterioration or lack of improvement with a likely intraabdominal cause

• Multidisciplinary team

Page 44: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Criteria for relaparotomy

On-demand

• Clinical deterioration or lack of improvement with a likely intraabdominal cause

• Multidisciplinary team

>4 points increase in the MOD-Score

MOD-Score unchanged for 48 hours

Abdominal CompartmentBleedingHemodynamic instabilityBurst AbdomenAnastomotic leakAbscess

Page 45: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Multi Organ Dysfunction Score

Marshall JC, Crit Care Med 1995

Page 46: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 47: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 48: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 49: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with
Page 50: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

Key points

• Heterogeneous cohort of patients

• In open abdomen:

– life before abdominal wall

– NPWT current standard

• 2nd look on demand in selected cases

– Reduction in relaparotomies

– Less health care utilization

• Multidisciplinary approach

Page 51: M. K. Müller Kantonsspital Frauenfeld das... · Treatment of secondary peritonitis e.g. after bariatric surgery • Irrigate & drain the abdominal cavity • Seal the leaks with

MKM 08.11.2018

Danke für die Aufmerksamkeit