masterclass of sarcoma and rare cancers

M A S T E R C L A S SOF SARCOMA

AND RARE CANCERS

Congress & Event Planning2-4 Kastriotou Str. | Athens - Greece P.O.11476

Τ +30 210 7294559 E [email protected]

ORGANIZED BYHellenic Group of Sarcoma and Rare Cancers

UNDER THE AUSPICES OF

NOVEMBER 13-14, 2020WEB SCIENTIFIC EVENT

MASTERCLASS OF SARCOMA AND RARE CANCERS MASTERCLASS OF SARCOMA AND RARE CANCERSNOVEMBER 13-14, 2020 WEB SCIENTIFIC EVENT NOVEMBER 13-14, 2020 WEB SCIENTIFIC EVENT

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WELCOME LETTERDear Collegues,

The Hellenic Group of Sarcoma and Rare Cancers (HGSRC) organizes, on November 13-14, 2020, the 3rd Masterclass of

Sarcoma and Rare Cancers. The event aims to induce an interest in the challenging field of sarcomas amongst the medical

community, by combining background knowledge and contemporary developments in the diagnosis and management of

these rare diseases. The Masterclass is addressed to pathologists, oncologists, radiation oncologists, radiologists, sur-

geons as well as any other scientific groups with special interest on sarcomas.

The sessions held during the Masterclass will include a thorough presentation of the clinical, morphological and molecular

characteristics of different sarcoma subtypes, with emphasis on the latest diagnostic and therapeutic advances in each

area. A prestigious faculty from all over Europe representing various disciplines involved in the management of sarcomas

ensures the highest quality of the scientific and didactic sessions.

The success of this effort relies upon comprehensive work, but also on everyone’s dedication and active support.

Within the grounds of the Masterclass of Sarcomas and Rare Cancers, we want to welcome you and warmly thank you for

your participation.

The Organizing Committee,

A. Stergioula

MD, Radiation OncologistDepartment of Radiation Oncology “Iaso”Department of Tomotherapy “Iatropolis”

Department of Stereotactic Radiosurgery - Cyberknife “Iatropolis”, Athens, Greece

A. Kyriazoglou

MD, PhD, Medical Oncologist, National & Kapodistrian University of Athens,

2nd Propaedeutic Department of Medicine,‘‘Attikon’’ University Hospital,

Athens, Greece

D.J. Papachristou

MD, PhD, HistopathologistProfessor Unit of Bone and Soft Tissue Studies,

Univ. of Patras School of Medicine, Patras GreeceAdj. Professor Department of PathologyUniv. of Pittsburgh, Pittsburgh, PA, USA

Scientific Coordinator, Dept. of Pathology‘‘Olympion’’ General Clinic, Patras, Greece


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ORGANIZING COMMITTEEA. Kyriazoglou

D.J. Papachristou

A. Stergioula

SCIENTIFIC COMMITTEEI. Agrogiannis

I. Athanasiadis

I. Boukovinas

A. Constantinidou

E. de Bree

A. Digklia

J. Duran Moreno

V. Georgoulias

S. Kokkali

V. Kontogeorgakos

N. Memos

I. Papanastasiou

V. Ramfidis

E. Skarpidi


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FRIDAY 13/11/202010.00 O P E N I N G S P E E C H A. Kyriazoglou, D.J. Papachristou, A. Stergioula T h e O r g a n i z i n g C o m m i t t e e

10.00-11.30 Gist Chairing: A. Koumarianou, E. de Bree, D. Voros

10.00-10.30 Current treatment options for advanced, inoperable, Μ. Karamouzis metastatic GIST 10.30-11.00 Mechanisms of Resistance of recurrent and metastatic GIST J. Duran-Moreno 11.00-11.30 Surgical approach of GIST N. Memos

11.30-11.40 B R E A K

11.40-13.40 Rare and Pediatric Sarcomas Chairing: A. Kyriazoglou, I. Papanastasiou

11.40-12.10 Challenges in pediatric sarcoma imaging M. Vlychou 12.10-12.40 Lung sarcomas: a study of the Hellenic Group V. Ramfidis 12.40-13.10 A case series of BCOR sarcomas from the Hellenic Group A. Kyriazoglou 13.10-13.40 NTRK rearranged mesenchymal tumors: pathologic approach* E. Skarpidi *Satellite lecture by Roche Diagnostics

13.40-13.50 B R E A K

13.50-15.50 New Modalities in the Diagnostics of Sarcomas Chairing: G. Nasioulas, P. Korkolopoulou

13.50-14.20 The emerging role of molecular pathology in sarcomas P. Costeas 14.20-14.50 The dark matter of the genomes: the non coding RNAs in sarcomas C. Stathopoulos 14.50-15.20 NTRK in sarcomas. Diagnostic strategy C. Valverde 15.20-15.50 NGS in sarcomas E. Papadopoulou

15.50-16.00 B R E A K

16.00-18.30 Soft Tissue Sarcomas I Chairing: D.J. Papachristou, A. Psyrri

16.00-16.30 Radiomics in soft tissue sarcomas A. Karantanas 16.30-17.00 Changes in WHO classification of STS E. Skarpidi 17.00-17.30 Management of Oligometastatic disease in the lung A. Costantinidou 17.30-18.00 Advanced soft tissue sarcomas: Beyond olaratumab R. Jones 18.00-18.30 Latest advances to address the risk of localized ESTS and RPS A. Gronchi

18.30 C L O S I N G R E M A R K S


SATURDAY 14/11/202010.00-11.30 Leiomyosarcomas Chairing: A. Stergioula, K. Diamantopoulou

10.00-10.30 RT in uLMS A. Kougioumtzopoulou 10.30-11.00 Extra - uterine leiomyosarcomas, pathology risk I. Agrogiannis 11.00-11.30 Current treatment options in LMS and future perspectives S. Kokkali

11.30-11.40 B R E A K

11.40-13.40 Bone Sarcomas Chairing: T. Makatsoris, T. Kormas, G. Koukoulis

11.40-12.10 Changes in WHO classification of bone tumors A. HG Cleven 12.10-12.40 Imaging of bone sarcomas M. Tzalonikou 12.40-13.10 Osteosarcoma surgical approach P. Megas 13.10-13.40 Pelvic sarcomas V. Kontogeorgakos

13.40-13.50 B R E A K

13.50-16.20 Soft Tissue Sarcomas II Chairing: H. Kalofonos, V. Georgoulias, I. Athanasiadis

13.50-14.20 WHO classification changes and clinical utility J.Y. Blay 14.20-14.50 Mesenchymal stem cells: key drivers to sarcoma development, D.J. Papachristou diagnosis and therapy 14.50-15.20 Treatment of retroperitoneal sarcoma after STRASS results S. Bonvalot 15.20-15.50 Liposarcomas: Treatment options in advanced setting A. Digklia 15.50-16.20 Cryoablation in desmoid tumors J.E. Kurtz

16.20-16.30 B R E A K

16.30-17.50 Sarcoma Cases: State-of-the-art Approach Chairing: I. Agrogiannis, S. Kokkali

16.30-16.50 Case 1 D. Tzanis 16.50-17.10 Case 2 C. Vallilas 17.10-17.30 Case 3 I. Athanasiadis 17.30-17.50 Case 4 S. Stavrianos

17.50-18.00 B R E A K

18.00-19.00 Policy of Sarcomas and Rare Diseases Chairing: D.J. Papachristou, A. Stergioula, A. Kyriazoglou

18.10-18.30 Learning from networks in rare diseases - introducing the Scottish Sarcoma Network experience J. Nixon 18.30-19.00 Policy of sarcoma management I. Boukovinas

19.00 C O N C L U S I O N S

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FACULTYI. Agrogiannis MD, PhD, Associate Professor of Pathology, 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens, Greece

I. Athanasiadis Medical Oncologist, Director of Oncology Clinic ‘‘Mitera’’ (Ygeia Group), Athens, Greece, Associate Professor of Oncology, Northwestern University, Chicago, U.S.A.

J.Y. Blay President UNICANCER, General Director, Centre Léon Bérard & University of Lyon, France

S. Bonvalot Chair Sarcoma Service, Department of Surgery, Institut Curie, Paris, France

I. Boukovinas MD, PhD, PharmaD, Medical Oncologist, Head of Oncology Unit, ‘‘Bioclinic’’ Thessaloniki, Greece

Α. HG Cleven MD, PhD, Pathologist, Department of Pathology, Leiden University Medical Center, The Netherlands

A. Constantinidou MD, MRCP, MSc, PhD, Medical Oncologist, Medical School University of Cyprus & BoC Oncology Centre, Nicosia, Cyprus

P. Costeas PhD, Executive Director, Karaiskakio Foundation, The Center for the Study of Haematological and Other Malignacies, Nicosia Cyprus

E. de Bree Professor of General Surgery & Surgical Oncology, Medical School of Crete, Department of Surgical Oncology, University Hospital, Heraklion, Crete, Greece

K. Diamantopoulou MD, Head of Pathology Department, ‘‘KAT’’ Hospital, Athens, Greece

A. Digklia MD, MSc, Consultant Oncologist, Department of Oncology, University Hospital of Lausanne (CHUV), Switzerland

J. Duran - Moreno MD, MSc, Medical Oncologist, Oncology Unit, 4th Department of Internal Medicine, Medical School, National and Kapodistrian University of Athens, Greece

V. Georgoulias Emeritus Professor of Medical Oncology, School of Medicine, University of Crete, Heraklion, Crete, Greece

A. Gronchi MD, Chair Sarcoma Service, Department of Surgery, IRCCS National Cancer Institute (INT), Milan, Italy

R. Jones Royal Marsden Hospital and Institute of Cancer Research, London, UK

H. Kalofonos Medical Oncologist, Emeritus Professor, University of Patras, Greece

M. Karamouzis MD, PhD, Medical Oncologist, Associate Professor, National and Kapodistrian University of Athens, Greece

A. Karantanas Professor of Radiology, University of Crete, Chairman Department of Radiology, School of Medicine, Chairman Department of Medical Imaging, Heraklionn University Hospital, Head - Advanced Hybrid Imaging Systems, ICS - FORTH, Heraklion, Crete, Greece

S. Kokkali MD, MSc, Consultant Medical Oncologist, 1st Department of Medical Oncology, ‘‘Saint Savvas’’ Anticancer Hospital, Athens, Greece

V. Kontogeorgakos Assistant Professor of Orthopaedics Surgery, Medical School, University of Athens, Greece

P. Korkolopoulou Professor, 1st Department of Pathology, National & Kapodistrian University of Athens, Medical School, Athens, Greece

T. Kormas MD, Clinical Director, Head of Orthopaedic Surgery & Bone Tumors Division, ‘‘Saint Savvas’’ Hospital, Athens, Greece

A. Kougioumtzopoulou MD, MSc, Radiation Oncologist, General Radiotherapy Unit, 2nd Department of Radiology, ‘‘Attikon’’ University Hospital, Athens, Greece

G. Koukoulis Professor of Pathology, University of Thessaly, Larissa, Greece

A. Koumarianou MD, PhD in Tumor Immunotherapies, Imperial College, Consultant in Medical Oncology, Hematology Oncology Unit, 4th Department of Internal Medicine, ‘‘Attikon’’ University Hospital, National & Kapodistrian University of Athens, Medical School, Athens, Greece


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A. Kyriazoglou MD, PhD, Medical Oncologist, National & Kapodistrian University of Athens, 2nd Propaedeutic Department of Medicine, ‘‘Attikon’’ University Hospital, Athens, Greece

J.E. Kurtz Department of Medical Oncology, ICANS Strasbourg Cancer Institute, Strasbourg, France

T. Makatsoris Associate Professor of Medical Oncology, University of Patras Medical School, Division of Oncology, University Hospital of Patras, Greece

P. Megas Professor of Orthopaedic, University of Patras, Medical School, Director of Orthopaedic Clinic in Patras University Hospital, Patras, Greece

N. Memos MD, PhD, MSc, Surgical Oncologist, Sarcoma and Rare Tumours Unit, ‘‘Aretaieio’’ University Hospital, Athens Medical School, Athens, Greece

G. Nasioulas PhD, Chief Scientific Officer, Genekor Medical S.A., Athens, Greece

J. Nixon Consultant Clinical Oncologist & Visiting Professor Strathclyde University, Sarcoma/Head and Neck, National Clinical Lead for Sarcomas in Scotland, NCRI UK Chair for Epidemiology and Survivorship H&N cancers, Beatson West of Scotland Cancer Center, Glasgow, UK

D.J. Papachristou MD, PhD, Consultant Histopathologist, Professor at University of Patras, School of Medicine, Scientific Coordinator, Unit of Bone and Soft Tissue Studies, Department of Anatomy-Histology-Embryology, Adj. Professor, Department of Pathology, University of Pittsburgh, PA, USA, Scientific Coordinator, Department of Pathology ‘‘Olympion’’ General Clinic, Patras, Greece

E. Papadopoulou PhD, Group Leader of Molecular Oncology, Genekor Medical S.A., Athens, Greece

I. Papanastasiou MD, PhD, Orthopedic Oncologist, General Oncological Hospital Kifissias ‘‘Agioi Anargyroi’’, Athens, Greece

A. Psyrri Associate Professor of Pathology - Oncology, Head of Oncology Department, ‘‘Attikon’’ University Hospital, Athens, Greece

V. Ramfidis MD, MSc, Medical Oncologist, 251 General Air Force Hospital, ‘‘Sotiria’’ General Hospital University of Athens, Greece

E. Skarpidi MD, DABP, FCAP, Scientific Director, Micromedia Labs, Athens, Greece

C. Stathopoulos Professor and Head, Department of Biochemistry, School of Medicine, University of Patras, Greece

S. Stavrianos MD, FEBOPRAS, Head & Neck, Plastic and Reconstructive Surgeon, Head Microvascular & Sarcomas Unit, Plastic Surgery Department, The Greek Anticancer Institute, Athens, Greece

A. Stergioula MD, Radiation Oncologist, Department of Radiation Oncology “Iaso”, Department of TomoTherapy “Iatropolis”, Department of Stereotactic Radiosurgery - CyberKnife “Iatropolis”, Athens, Greece

M. Tzalonikou MD, Consultant Radiologist, ‘‘Vioiatriki’’ Medical Group, Athens, Greece

D. Tzanis MD, PhD, Department of Surgery, Institut ‘‘Curie’’, Paris, France

C. Vallilas MD, Internist, ‘‘Evgenideio’’ Hospital and Phd Candidate, Biochemistry Laboratory of Medical School, University of Athens, Greece

C. Valverde MD, Medical Oncology Service, Vall d’Hebron University Hospital, Barcelona, Spain

M. Vlychou Professor of Radiology, School of Medicine, University of Thessaly, Director of the Department of Radiology, University Hospital of Larissa, Greece

D. Voros Emeritus Professor of Surgery, University of Athens, Chief of Surgery, 3rd Department of ‘‘Henry Dunant’’ Hospital Athens, Greece


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INFOOrganizer

Hellenic Group of Sarcoma and Rare Cancers

Under the Auspices of

DateNovember 13-14, 2020

WEB SCIENTIFIC EVENT

Official languageThe official language of the Meeting is English.

Τhere will be a live streaming connection through a special platform.You can watch the Conference online through the link www.nowcongress.gr and ask written questions throughout the presentations.

Certificate of AttendanceThe certificate of attendance will be given to the participants at the end of the event.Based on the latest circular of the National Drug Organization the Event is required to use an attendance tracking system. By the end of the event a certificate will be sent to those who have attended at least 60% of the total hours of the scientific Program. The number of credits of Continuing Medical Education (CME-CPD) to be administered to the participants will be calculated on the basis of monitoring time.

The event will be awardedBy Hellenic Medical Association (Ph. M.A.) with 16 CME - CPD credits.

The Secretariat

Congress & Event Planning2-4 Kastriotou Str. | Athens - Greece P.O.11476 Τ +30 210 7294559 E [email protected]


SpONSORS

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Congress & Event Planning2-4 Kastriotou Str. | Athens - Greece P.O.11476 Τ +30 210 7294559 E [email protected] www.eventema.gr

masterclass of sarcoma and rare cancers

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